Skip to main content

Main menu

  • Home
  • Articles
    • Current Issue
    • Next in The JI
    • Archive
    • Brief Reviews
    • Pillars of Immunology
    • Translating Immunology
    • Most Read
    • Top Downloads
    • Annual Meeting Abstracts
  • COVID-19/SARS/MERS Articles
  • Info
    • About the Journal
    • For Authors
    • Journal Policies
    • Influence Statement
    • For Advertisers
  • Editors
  • Submit
    • Submit a Manuscript
    • Instructions for Authors
    • Journal Policies
  • Subscribe
    • Journal Subscriptions
    • Email Alerts
    • RSS Feeds
    • ImmunoCasts
  • More
    • Most Read
    • Most Cited
    • ImmunoCasts
    • AAI Disclaimer
    • Feedback
    • Help
    • Accessibility Statement
  • Other Publications
    • American Association of Immunologists
    • ImmunoHorizons

User menu

  • Subscribe
  • Log in

Search

  • Advanced search
The Journal of Immunology
  • Other Publications
    • American Association of Immunologists
    • ImmunoHorizons
  • Subscribe
  • Log in
The Journal of Immunology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Next in The JI
    • Archive
    • Brief Reviews
    • Pillars of Immunology
    • Translating Immunology
    • Most Read
    • Top Downloads
    • Annual Meeting Abstracts
  • COVID-19/SARS/MERS Articles
  • Info
    • About the Journal
    • For Authors
    • Journal Policies
    • Influence Statement
    • For Advertisers
  • Editors
  • Submit
    • Submit a Manuscript
    • Instructions for Authors
    • Journal Policies
  • Subscribe
    • Journal Subscriptions
    • Email Alerts
    • RSS Feeds
    • ImmunoCasts
  • More
    • Most Read
    • Most Cited
    • ImmunoCasts
    • AAI Disclaimer
    • Feedback
    • Help
    • Accessibility Statement
  • Follow The Journal of Immunology on Twitter
  • Follow The Journal of Immunology on RSS

Table of Contents

December 15, 2017; Volume 199,Issue 12

IN THIS ISSUE

  • You have accessRestricted access
    In This Issue

    CD28 Drives TFR Differentiation and Function See article p. 3972

    Sinking Teeth into Periodontitis See article p. 4023

    Protective IL-22 Binding Protein See article p. 4078

    Capturing Plasmablasts To Study Vaccine Responses See article p. 4180

    J Immunol December 15, 2017, 199 (12) 3927-3928; DOI: https://doi.org/10.4049/jimmunol.1790022

CUTTING EDGE

  • You have accessRestricted access
    Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes
    Joshua D. Wheaton, Chen-Hao Yeh and Maria Ciofani
    J Immunol December 15, 2017, 199 (12) 3931-3936; DOI: https://doi.org/10.4049/jimmunol.1701134
  • You have accessRestricted access
    Cutting Edge: Processing of Oxidized Peptides in Macrophages Regulates T Cell Activation and Development of Autoimmune Arthritis
    Min Yang, Claus Haase, Johan Viljanen, Bingze Xu, Changrong Ge, Jan Kihlberg and Rikard Holmdahl
    J Immunol December 15, 2017, 199 (12) 3937-3942; DOI: https://doi.org/10.4049/jimmunol.1700774

ALLERGY AND OTHER HYPERSENSITIVITIES

  • You have accessRestricted access
    Lung-Infiltrating Foxp3+ Regulatory T Cells Are Quantitatively and Qualitatively Different during Eosinophilic and Neutrophilic Allergic Airway Inflammation but Essential To Control the Inflammation
    Eunjung Jang, Quang Tam Nguyen, Sohee Kim, Dongkyun Kim, Thi Hong Nga Le, Karen Keslar, Nina Dvorina, Mark A. Aronica and Booki Min
    J Immunol December 15, 2017, 199 (12) 3943-3951; DOI: https://doi.org/10.4049/jimmunol.1700211
  • You have accessRestricted access
    Endogenous Calcitriol Synthesis Controls the Humoral IgE Response in Mice
    Juliane Lindner, Sebastian Rausch, Sandra Treptow, Kerstin Geldmeyer-Hilt, Tina Krause, René St-Arnaud, Alice Arabian, Andreas Radbruch, Susanne Hartmann, Margitta Worm and Guido Heine
    J Immunol December 15, 2017, 199 (12) 3952-3958; DOI: https://doi.org/10.4049/jimmunol.1602080

ANTIGEN RECOGNITION AND RESPONSES

  • You have accessRestricted access
    Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen
    Yasuhiro Mouri, Yoshihiro Ueda, Tomoyoshi Yamano, Minoru Matsumoto, Koichi Tsuneyama, Tatsuo Kinashi and Mitsuru Matsumoto
    J Immunol December 15, 2017, 199 (12) 3959-3971; DOI: https://doi.org/10.4049/jimmunol.1700892

AUTOIMMUNITY

  • You have accessRestricted access
    B Cells Drive Autoimmunity in Mice with CD28-Deficient Regulatory T Cells
    Ruan Zhang, Peter T. Sage, Kelsey Finn, Alexandria Huynh, Bruce R. Blazar, Francesco Marangoni, Thorsten R. Mempel, Arlene H. Sharpe and Laurence A. Turka
    J Immunol December 15, 2017, 199 (12) 3972-3980; DOI: https://doi.org/10.4049/jimmunol.1700409
  • You have accessRestricted access
    Broad Susceptibility of Nucleolar Proteins and Autoantigens to Complement C1 Protease Degradation
    Yitian Cai, Seng Yin Kelly Wee, Junjie Chen, Boon Heng Dennis Teo, Yee Leng Carol Ng, Khai Pang Leong and Jinhua Lu
    J Immunol December 15, 2017, 199 (12) 3981-3990; DOI: https://doi.org/10.4049/jimmunol.1700728
  • You have accessRestricted access
    The Type 1 Diabetes–Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice
    Robert L. Whitener, Lisa Gallo Knight, Jianwei Li, Sarah Knapp, Shuyao Zhang, Mani Annamalai, Vadim M. Pliner, Dongtao Fu, Ilian Radichev, Christina Amatya, Alexei Savinov, Arif Yurdagul Jr., Shuai Yuan, John Glawe, Christopher G. Kevil, Jing Chen, Scott E. Stimpson and Clayton E. Mathews
    J Immunol December 15, 2017, 199 (12) 3991-4000; DOI: https://doi.org/10.4049/jimmunol.1602037
  • You have accessRestricted access
    Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers
    Stephanie L. Schell, Chetna Soni, Melinda J. Fasnacht, Phillip P. Domeier, Timothy K. Cooper and Ziaur S. M. Rahman
    J Immunol December 15, 2017, 199 (12) 4001-4015; DOI: https://doi.org/10.4049/jimmunol.1700611
  • You have accessRestricted access
    SATB1 Conditional Knockout Results in Sjögren’s Syndrome in Mice
    Yuriko Tanaka, Takehiko Sotome, Akiko Inoue, Takanori Mukozu, Taku Kuwabara, Tetuo Mikami, Terumi Kowhi-Shigematsu and Motonari Kondo
    J Immunol December 15, 2017, 199 (12) 4016-4022; DOI: https://doi.org/10.4049/jimmunol.1700550

CLINICAL AND HUMAN IMMUNOLOGY

  • You have accessRestricted access
    Gingival Tissue Inflammation Promotes Increased Matrix Metalloproteinase-12 Production by CD200Rlow Monocyte-Derived Cells in Periodontitis
    Sofia Björnfot Holmström, Reuben Clark, Stephanie Zwicker, Daniela Bureik, Egle Kvedaraite, Eric Bernasconi, Anh Thu Nguyen Hoang, Gunnar Johannsen, Benjamin J. Marsland, Elisabeth A. Boström and Mattias Svensson
    J Immunol December 15, 2017, 199 (12) 4023-4035; DOI: https://doi.org/10.4049/jimmunol.1700672
  • You have accessRestricted access
    Disruption of Thrombocyte and T Lymphocyte Development by a Mutation in ARPC1B
    Raz Somech, Atar Lev, Yu Nee Lee, Amos J. Simon, Ortal Barel, Ginette Schiby, Camila Avivi, Iris Barshack, Michele Rhodes, Jiejing Yin, Minshi Wang, Yibin Yang, Jennifer Rhodes, Nufar Marcus, Ben-Zion Garty, Jerry Stein, Ninette Amariglio, Gideon Rechavi, David L. Wiest and Yong Zhang
    J Immunol December 15, 2017, 199 (12) 4036-4045; DOI: https://doi.org/10.4049/jimmunol.1700460
  • You have accessRestricted access
    Proinflammatory T Cell Status Associated with Early Life Adversity
    Martha M. C. Elwenspoek, Xenia Hengesch, Fleur A. D. Leenen, Anna Schritz, Krystel Sias, Violetta K. Schaan, Sophie B. Mériaux, Stephanie Schmitz, Fanny Bonnemberger, Hartmut Schächinger, Claus Vögele, Jonathan D. Turner and Claude P. Muller
    J Immunol December 15, 2017, 199 (12) 4046-4055; DOI: https://doi.org/10.4049/jimmunol.1701082

IMMUNE REGULATION

  • You have accessRestricted access
    Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation
    Charles W. Tran, Samuel D. Saibil, Thierry Le Bihan, Sara R. Hamilton, Karl S. Lang, Han You, Amy E. Lin, Kristine M. Garza, Alisha R. Elford, Kelly Tai, Michael E. Parsons, Kip Wigmore, Mitchell G. Vainberg, Josef M. Penninger, James R. Woodgett, Tak W. Mak and Pamela S. Ohashi
    J Immunol December 15, 2017, 199 (12) 4056-4065; DOI: https://doi.org/10.4049/jimmunol.1600396
  • You have accessRestricted access
    Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis
    Xiaotong Cui, Takashi Mino, Masanori Yoshinaga, Yoshinari Nakatsuka, Fabian Hia, Daichi Yamasoba, Tohru Tsujimura, Keizo Tomonaga, Yutaka Suzuki, Takuya Uehata and Osamu Takeuchi
    J Immunol December 15, 2017, 199 (12) 4066-4077; DOI: https://doi.org/10.4049/jimmunol.1701211
  • You have accessRestricted access
    A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury
    Dörte Kleinschmidt, Anastasios D. Giannou, Heather M. McGee, Jan Kempski, Babett Steglich, Francis Jessica Huber, Thomas Michael Ernst, Ahmad Mustafa Shiri, Claudia Wegscheid, Elena Tasika, Peter Hübener, Philipp Huber, Tanja Bedke, Niklas Steffens, Theodora Agalioti, Tobias Fuchs, Jill Noll, Hannelore Lotter, Gisa Tiegs, Ansgar W. Lohse, Jonathan H. Axelrod, Eithan Galun, Richard A. Flavell, Nicola Gagliani and Samuel Huber
    J Immunol December 15, 2017, 199 (12) 4078-4090; DOI: https://doi.org/10.4049/jimmunol.1700587
  • Open Access
    TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1

    Author Choice Article

    Nina Chi Sabins, Olesya Chornoguz, Karen Leander, Fred Kaplan, Richard Carter, Michelle Kinder, Kurtis Bachman, Raluca Verona, Shixue Shen, Vipul Bhargava and Sandra Santulli-Marotto
    J Immunol December 15, 2017, 199 (12) 4091-4102; DOI: https://doi.org/10.4049/jimmunol.1701030

IMMUNOTHERAPY AND VACCINES

  • Open Access
    IgG1 Is Required for Optimal Protection after Immunization with the Purified Porin OmpD from Salmonella Typhimurium

    Author Choice Article

    Yang Zhang, Coral Dominguez-Medina, Nicola J. Cumley, Jennifer N. Heath, Sarah J. Essex, Saeeda Bobat, Anna Schager, Margaret Goodall, Sven Kracker, Christopher D. Buckley, Robin C. May, Robert A. Kingsley, Calman A. MacLennan, Constantino López-Macías, Adam F. Cunningham and Kai-Michael Toellner
    J Immunol December 15, 2017, 199 (12) 4103-4109; DOI: https://doi.org/10.4049/jimmunol.1700952
  • Open Access
    CD27-Mediated Regulatory T Cell Depletion and Effector T Cell Costimulation Both Contribute to Antitumor Efficacy

    Author Choice Article

    Anna Wasiuk, James Testa, Jeff Weidlick, Crystal Sisson, Laura Vitale, Jenifer Widger, Andrea Crocker, Lawrence J. Thomas, Joel Goldstein, Henry C. Marsh, Tibor Keler and Li-Zhen He
    J Immunol December 15, 2017, 199 (12) 4110-4123; DOI: https://doi.org/10.4049/jimmunol.1700606

INNATE IMMUNITY AND INFLAMMATION

  • You have accessRestricted access
    Serum IgA Immune Complexes Promote Proinflammatory Cytokine Production by Human Macrophages, Monocytes, and Kupffer Cells through FcαRI–TLR Cross-Talk
    Ivo S. Hansen, Willianne Hoepel, Sebastiaan A. J. Zaat, Dominique L. P. Baeten and Jeroen den Dunnen
    J Immunol December 15, 2017, 199 (12) 4124-4131; DOI: https://doi.org/10.4049/jimmunol.1700883
  • You have accessRestricted access
    Copper Regulates Maturation and Expression of an MITF:Tryptase Axis in Mast Cells
    Jun Mei Hu Frisk, Lena Kjellén, Stephen G. Kaler, Gunnar Pejler and Helena Öhrvik
    J Immunol December 15, 2017, 199 (12) 4132-4141; DOI: https://doi.org/10.4049/jimmunol.1700786

MOLECULAR AND STRUCTURAL IMMUNOLOGY

  • You have accessRestricted access
    Ubc9 Binds to ADAP and Is Required for Rap1 Membrane Recruitment, Rac1 Activation, and Integrin-Mediated T Cell Adhesion
    Yiwei Xiong, Chengjin Ye, Naiqi Yang, Madanqi Li and Hebin Liu
    J Immunol December 15, 2017, 199 (12) 4142-4154; DOI: https://doi.org/10.4049/jimmunol.1700572

SYSTEMS IMMUNOLOGY

  • You have accessRestricted access
    Virtual Sorting Has a Distinctive Advantage in Identification of Anticorrelated Genes and Further Negative Regulators of Immune Cell Subpopulations
    Pingzhang Wang, Wenling Han and Dalong Ma
    J Immunol December 15, 2017, 199 (12) 4155-4164; DOI: https://doi.org/10.4049/jimmunol.1700946

NOVEL IMMUNOLOGICAL METHODS

  • Open Access
    Development of a Novel CD4+ TCR Transgenic Line That Reveals a Dominant Role for CD8+ Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria

    Author Choice Article

    Daniel Fernandez-Ruiz, Lei Shong Lau, Nazanin Ghazanfari, Claerwen M. Jones, Wei Yi Ng, Gayle M. Davey, Dorothee Berthold, Lauren Holz, Yu Kato, Matthias H. Enders, Ganchimeg Bayarsaikhan, Sanne H. Hendriks, Lianne I. M. Lansink, Jessica A. Engel, Megan S. F. Soon, Kylie R. James, Anton Cozijnsen, Vanessa Mollard, Alessandro D. Uboldi, Christopher J. Tonkin, Tania F. de Koning-Ward, Paul R. Gilson, Tsuneyasu Kaisho, Ashraful Haque, Brendan S. Crabb, Francis R. Carbone, Geoffrey I. McFadden and William R. Heath
    J Immunol December 15, 2017, 199 (12) 4165-4179; DOI: https://doi.org/10.4049/jimmunol.1700186
  • You have accessRestricted access
    Isolation and Characterization of Antigen-Specific Plasmablasts Using a Novel Flow Cytometry–Based Ig Capture Assay
    Christopher L. Pinder, Sven Kratochvil, Deniz Cizmeci, Luke Muir, Yanping Guo, Robin J. Shattock and Paul F. McKay
    J Immunol December 15, 2017, 199 (12) 4180-4188; DOI: https://doi.org/10.4049/jimmunol.1701253
Back to top
PreviousNext
PreviousNext

This Issue

The Journal of Immunology: 199 (12)
The Journal of Immunology
Vol. 199, Issue 12
15 Dec 2017
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Advertising (PDF)
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)

Issue highlights

  • In This Issue
Sign up for alerts

Jump to

  • IN THIS ISSUE
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
  • ANTIGEN RECOGNITION AND RESPONSES
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNOTHERAPY AND VACCINES
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • SYSTEMS IMMUNOLOGY
  • NOVEL IMMUNOLOGICAL METHODS
  • Highlights
  • Most Cited
  • Most Read
Loading
Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

Navigate

  • Home
  • Current Issue
  • Next in The JI
  • Archive
  • Brief Reviews
  • Pillars of Immunology
  • Translating Immunology

For Authors

  • Submit a Manuscript
  • Instructions for Authors
  • About the Journal
  • Journal Policies
  • Editors

General Information

  • Advertisers
  • Subscribers
  • Rights and Permissions
  • Accessibility Statement
  • FAR 889
  • Privacy Policy
  • Disclaimer

Journal Services

  • Email Alerts
  • RSS Feeds
  • ImmunoCasts
  • Twitter

Copyright © 2022 by The American Association of Immunologists, Inc.

Print ISSN 0022-1767        Online ISSN 1550-6606