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Table of Contents

April 15, 2016; Volume 196,Issue 8

IN THIS ISSUE

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    In This Issue

    Th17 Turmoil in Metabolic Dysfunction See article p. 3287

    Foiling Phagocytosis To Ameliorate Inflammation See article p. 3331

    Giving ADIN a TRIM See article p. 3452

    Rac-ing Up Isoform Dynamics See article p. 3479

    J Immunol April 15, 2016, 196 (8) 3215-3216; DOI: https://doi.org/10.4049/jimmunol.1690004

BRIEF REVIEWS

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    Environmental Immunology: Lessons Learned from Exposure to a Select Panel of Immunotoxicants
    Joanna M. Kreitinger, Celine A. Beamer and David M. Shepherd
    J Immunol April 15, 2016, 196 (8) 3217-3225; DOI: https://doi.org/10.4049/jimmunol.1502149

CUTTING EDGE

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    Cutting Edge: CLEC5A Mediates Macrophage Function and Chronic Obstructive Pulmonary Disease Pathologies
    Brian W. Wortham, Bryan L. Eppert, Jennifer L. Flury, Sara Morgado Garcia, Walter R. Donica, Andrew Osterburg, Barbara Joyce-Shaikh, Daniel J. Cua and Michael T. Borchers
    J Immunol April 15, 2016, 196 (8) 3227-3231; DOI: https://doi.org/10.4049/jimmunol.1500978

ALLERGY AND OTHER HYPERSENSITIVITIES

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    Control of the Physical and Antimicrobial Skin Barrier by an IL-31–IL-1 Signaling Network
    Kai H. Hänel, Carolina M. Pfaff, Christian Cornelissen, Philipp M. Amann, Yvonne Marquardt, Katharina Czaja, Arianna Kim, Bernhard Lüscher and Jens M. Baron
    J Immunol April 15, 2016, 196 (8) 3233-3244; DOI: https://doi.org/10.4049/jimmunol.1402943
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    α-NAC–Specific Autoreactive CD8+ T Cells in Atopic Dermatitis Are of an Effector Memory Type and Secrete IL-4 and IFN-γ
    Lennart M. Roesner, Annice Heratizadeh, Susanne Wieschowski, Irene Mittermann, Rudolf Valenta, Britta Eiz-Vesper, Christian Hennig, Gesine Hansen, Christine S. Falk and Thomas Werfel
    J Immunol April 15, 2016, 196 (8) 3245-3252; DOI: https://doi.org/10.4049/jimmunol.1500351

AUTOIMMUNITY

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    Dendritic Cells Guide Islet Autoimmunity through a Restricted and Uniquely Processed Peptidome Presented by High-Risk HLA-DR
    Menno van Lummel, Peter A. van Veelen, Arnoud H. de Ru, George M. C. Janssen, Jos Pool, Sandra Laban, Antoinette M. Joosten, Tatjana Nikolic, Jan W. Drijfhout, M. Luisa Mearin, Henk J. Aanstoot, Mark Peakman and Bart O. Roep
    J Immunol April 15, 2016, 196 (8) 3253-3263; DOI: https://doi.org/10.4049/jimmunol.1501282
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    Platelet-Derived Growth Factor Receptor Activation Promotes the Prodestructive Invadosome-Forming Phenotype of Synoviocytes from Patients with Rheumatoid Arthritis
    Martine Charbonneau, Roxane R. Lavoie, Annie Lauzier, Kelly Harper, Patrick P. McDonald and Claire M. Dubois
    J Immunol April 15, 2016, 196 (8) 3264-3275; DOI: https://doi.org/10.4049/jimmunol.1500502

CLINICAL AND HUMAN IMMUNOLOGY

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    HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
    Victor Y. Du, Anju Bansal, Jonathan Carlson, Jesus F. Salazar-Gonzalez, Maria G. Salazar, Kristin Ladell, Stephanie Gras, Tracy M. Josephs, Sonya L. Heath, David A. Price, Jamie Rossjohn, Eric Hunter and Paul A. Goepfert
    J Immunol April 15, 2016, 196 (8) 3276-3286; DOI: https://doi.org/10.4049/jimmunol.1502411
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    ATP-Induced Inflammation Drives Tissue-Resident Th17 Cells in Metabolically Unhealthy Obesity
    Julieta B. Pandolfi, Ariel A. Ferraro, Inés Sananez, Maria C. Gancedo, Plácida Baz, Luis A. Billordo, Leonardo Fainboim and Lourdes Arruvito
    J Immunol April 15, 2016, 196 (8) 3287-3296; DOI: https://doi.org/10.4049/jimmunol.1502506

IMMUNE REGULATION

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    STAT3 Impairs STAT5 Activation in the Development of IL-9–Secreting T Cells
    Matthew R. Olson, Felipe Fortino Verdan, Matthew M. Hufford, Alexander L. Dent and Mark H. Kaplan
    J Immunol April 15, 2016, 196 (8) 3297-3304; DOI: https://doi.org/10.4049/jimmunol.1501801
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    Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis
    Dipica Haribhai, Jennifer Ziegelbauer, Shuang Jia, Kyle Upchurch, Ke Yan, Erica G. Schmitt, Nita H. Salzman, Pippa Simpson, Martin J. Hessner, Talal A. Chatila and Calvin B. Williams
    J Immunol April 15, 2016, 196 (8) 3305-3317; DOI: https://doi.org/10.4049/jimmunol.1501956
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    Age-Associated Resident Memory CD8 T Cells in the Central Nervous System Are Primed To Potentiate Inflammation after Ischemic Brain Injury
    Rodney M. Ritzel, Joshua Crapser, Anita R. Patel, Rajkumer Verma, Jeremy M. Grenier, Anjali Chauhan, Evan R. Jellison and Louise D. McCullough
    J Immunol April 15, 2016, 196 (8) 3318-3330; DOI: https://doi.org/10.4049/jimmunol.1502021
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    CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor– and Complement Receptor 3–Dependent Mechanisms
    Alaa Amash, Lin Wang, Yawen Wang, Varsha Bhakta, Gregory D. Fairn, Ming Hou, Jun Peng, William P. Sheffield and Alan H. Lazarus
    J Immunol April 15, 2016, 196 (8) 3331-3340; DOI: https://doi.org/10.4049/jimmunol.1502198
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    ACKR4 on Stromal Cells Scavenges CCL19 To Enable CCR7-Dependent Trafficking of APCs from Inflamed Skin to Lymph Nodes
    Steven A. Bryce, Ruairi A. M. Wilson, Eleanor M. Tiplady, Darren L. Asquith, Shannon K. Bromley, Andrew D. Luster, Gerard J. Graham and Robert J. B. Nibbs
    J Immunol April 15, 2016, 196 (8) 3341-3353; DOI: https://doi.org/10.4049/jimmunol.1501542

IMMUNOTHERAPY AND VACCINES

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    Modification of Antigen Impacts on Memory Quality after Adenovirus Vaccination
    Julia M. Colston, Beatrice Bolinger, Matthew G. Cottingham, Sarah Gilbert and Paul Klenerman
    J Immunol April 15, 2016, 196 (8) 3354-3363; DOI: https://doi.org/10.4049/jimmunol.1502687
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    Combinatorial Synthetic Peptide Vaccine Strategy Protects against Hypervirulent CovR/S Mutant Streptococci
    Manisha Pandey, Rasmus Mortensen, Ainslie Calcutt, Jessica Powell, Michael R. Batzloff, Jes Dietrich and Michael F. Good
    J Immunol April 15, 2016, 196 (8) 3364-3374; DOI: https://doi.org/10.4049/jimmunol.1501994

INNATE IMMUNITY AND INFLAMMATION

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    MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells
    Luke M. Healy, Gabrielle Perron, So-Yoon Won, Mackenzie A. Michell-Robinson, Ayman Rezk, Samuel K. Ludwin, Craig S. Moore, Jeffery A. Hall, Amit Bar-Or and Jack P. Antel
    J Immunol April 15, 2016, 196 (8) 3375-3384; DOI: https://doi.org/10.4049/jimmunol.1502562
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    Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers
    Catalina Lee-Chang, Monica Bodogai, Kanako Moritoh, Xin Chen, Robert Wersto, Ranjan Sen, Howard A. Young, Michael Croft, Luigi Ferrucci and Arya Biragyn
    J Immunol April 15, 2016, 196 (8) 3385-3397; DOI: https://doi.org/10.4049/jimmunol.1502034
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    KIR3DL1 and HLA-B Density and Binding Calibrate NK Education and Response to HIV
    Jeanette E. Boudreau, Tiernan J. Mulrooney, Jean-Benoît Le Luduec, Edward Barker and Katharine C. Hsu
    J Immunol April 15, 2016, 196 (8) 3398-3410; DOI: https://doi.org/10.4049/jimmunol.1502469
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    IL-1β and Inflammasome Activity Link Inflammation to Abnormal Fetal Airway Development
    Ashley N. Stouch, Alyssa M. McCoy, Rachel M. Greer, Omar Lakhdari, Fiona E. Yull, Timothy S. Blackwell, Hal M. Hoffman and Lawrence S. Prince
    J Immunol April 15, 2016, 196 (8) 3411-3420; DOI: https://doi.org/10.4049/jimmunol.1500906
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    MicroRNA-487b Is a Negative Regulator of Macrophage Activation by Targeting IL-33 Production
    Yang Xiang, Fiona Eyers, Cristan Herbert, Hock L. Tay, Paul S. Foster and Ming Yang
    J Immunol April 15, 2016, 196 (8) 3421-3428; DOI: https://doi.org/10.4049/jimmunol.1502081
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    Resolvin D1 Polarizes Primary Human Macrophages toward a Proresolution Phenotype through GPR32
    Mattia Schmid, Claudio Gemperle, Nicole Rimann and Martin Hersberger
    J Immunol April 15, 2016, 196 (8) 3429-3437; DOI: https://doi.org/10.4049/jimmunol.1501701

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Usp9X Is Required for Lymphocyte Activation and Homeostasis through Its Control of ZAP70 Ubiquitination and PKCβ Kinase Activity
    Edwina Naik and Vishva M. Dixit
    J Immunol April 15, 2016, 196 (8) 3438-3451; DOI: https://doi.org/10.4049/jimmunol.1403165
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    TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
    Stian Foss, Ruth E. Watkinson, Algirdas Grevys, Martin B. McAdam, Malin Bern, Lene Stokken Høydahl, Bjørn Dalhus, Terje E. Michaelsen, Inger Sandlie, Leo C. James and Jan Terje Andersen
    J Immunol April 15, 2016, 196 (8) 3452-3459; DOI: https://doi.org/10.4049/jimmunol.1502601

TUMOR IMMUNOLOGY

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    Propranolol Attenuates Surgical Stress–Induced Elevation of the Regulatory T Cell Response in Patients Undergoing Radical Mastectomy
    Lei Zhou, Yunli Li, Xiaoxiao Li, Gong Chen, Huiying Liang, Yuhui Wu, Jianbin Tong and Wen Ouyang
    J Immunol April 15, 2016, 196 (8) 3460-3469; DOI: https://doi.org/10.4049/jimmunol.1501677
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    Myeloid-Derived Suppressor Cell Survival and Function Are Regulated by the Transcription Factor Nrf2
    Daniel W. Beury, Kayla A. Carter, Cassandra Nelson, Pratima Sinha, Erica Hanson, Maeva Nyandjo, Phillip J. Fitzgerald, Amry Majeed, Neha Wali and Suzanne Ostrand-Rosenberg
    J Immunol April 15, 2016, 196 (8) 3470-3478; DOI: https://doi.org/10.4049/jimmunol.1501785

NOVEL IMMUNOLOGICAL METHODS

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    Optical Tools To Study the Isoform-Specific Roles of Small GTPases in Immune Cells
    Veronika Miskolci, Bin Wu, Yasmin Moshfegh, Dianne Cox and Louis Hodgson
    J Immunol April 15, 2016, 196 (8) 3479-3493; DOI: https://doi.org/10.4049/jimmunol.1501655

CORRECTIONS

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    Correction: Cutting Edge: TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity
    Jorge Galindo-Villegas, Ana Montalban-Arques, Sergio Liarte, Sofia de Oliveira, Carlos Pardo-Pastor, Fanny Rubio-Moscardo, José Meseguer, Miguel A. Valverde and Victoriano Mulero
    J Immunol April 15, 2016, 196 (8) 3494; DOI: https://doi.org/10.4049/jimmunol.1600243
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    Correction: SATB1 Plays a Critical Role in Establishment of Immune Tolerance
    Motonari Kondo, Yuriko Tanaka, Taku Kuwabara, Taku Naito, Terumi Kohwi-Shigematsu and Akiko Watanabe
    J Immunol April 15, 2016, 196 (8) 3495; DOI: https://doi.org/10.4049/jimmunol.1600293
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The Journal of Immunology: 196 (8)
The Journal of Immunology
Vol. 196, Issue 8
15 Apr 2016
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  • IN THIS ISSUE
  • BRIEF REVIEWS
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNOTHERAPY AND VACCINES
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • TUMOR IMMUNOLOGY
  • NOVEL IMMUNOLOGICAL METHODS
  • CORRECTIONS
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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