The Journal of Immunology: 196 (4)

February 15, 2016; Volume 196,Issue 4

IN THIS ISSUE

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In This Issue
FRETting about Naive T Cells and Calcium See article p. 1471
IRFs Influence DC Differentiation See article p. 1666
Cytokines Skew CD8⁺ T Cells during Mycobacterium tuberculosis See article p. 1822
Lipid-Loving γδ T Cells See article p. 1933
Regulating Raft Recruitment See article p. 1955

J Immunol February 15, 2016, 196 (4) 1433-1434; DOI: https://doi.org/10.4049/jimmunol.1590030

BRIEF REVIEWS

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The Emerging Importance of IgG Fab Glycosylation in Immunity
Fleur S. van de Bovenkamp, Lise Hafkenscheid, Theo Rispens and Yoann Rombouts

J Immunol February 15, 2016, 196 (4) 1435-1441; DOI: https://doi.org/10.4049/jimmunol.1502136

CUTTING EDGE

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Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell–Mediated Central Nervous System Autoimmune Disease
Ryan C. Winger, Christopher T. Harp, Ming-Yi Chiang, David P. Sullivan, Richard L. Watson, Evan W. Weber, Joseph R. Podojil, Stephen D. Miller and William A. Muller

J Immunol February 15, 2016, 196 (4) 1443-1448; DOI: https://doi.org/10.4049/jimmunol.1501634
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Cutting Edge: Eomesodermin Is Sufficient To Direct Type 1 Innate Lymphocyte Development into the Conventional NK Lineage
Olga Pikovskaya, Julie Chaix, Nyanza J. Rothman, Amélie Collins, Yen-Hua Chen, Anna M. Scipioni, Eric Vivier and Steven L. Reiner

J Immunol February 15, 2016, 196 (4) 1449-1454; DOI: https://doi.org/10.4049/jimmunol.1502396
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Cutting Edge: MicroRNA-223 Regulates Myeloid Dendritic Cell–Driven Th17 Responses in Experimental Autoimmune Encephalomyelitis
Igal Ifergan, Siqi Chen, Bin Zhang and Stephen D. Miller

J Immunol February 15, 2016, 196 (4) 1455-1459; DOI: https://doi.org/10.4049/jimmunol.1501965

ALLERGY AND OTHER HYPERSENSITIVITIES

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Fluvastatin Suppresses Mast Cell and Basophil IgE Responses: Genotype-Dependent Effects
Elizabeth Motunrayo Kolawole, Jamie Josephine Avila McLeod, Victor Ndaw, Daniel Abebayehu, Brian O. Barnstein, Travis Faber, Andrew J. Spence, Marcela Taruselli, Anuya Paranjape, Tamara T. Haque, Amina A. Qayum, Qasim A. Kazmi, Dayanjan S. Wijesinghe, Jamie L. Sturgill, Charles E. Chalfant, David B. Straus, Carole A. Oskeritzian and John J. Ryan

J Immunol February 15, 2016, 196 (4) 1461-1470; DOI: https://doi.org/10.4049/jimmunol.1501932

ANTIGEN RECOGNITION AND RESPONSES

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Real-Time Analysis of Calcium Signals during the Early Phase of T Cell Activation Using a Genetically Encoded Calcium Biosensor
Marie Le Borgne, Saravanan Raju, Bernd H. Zinselmeyer, Viet T. Le, JiaJia Li, Yingxiao Wang, Mark J. Miller and Andrey S. Shaw

J Immunol February 15, 2016, 196 (4) 1471-1479; DOI: https://doi.org/10.4049/jimmunol.1502414
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The Length Distribution of Class I–Restricted T Cell Epitopes Is Determined by Both Peptide Supply and MHC Allele–Specific Binding Preference
Thomas Trolle, Curtis P. McMurtrey, John Sidney, Wilfried Bardet, Sean C. Osborn, Thomas Kaever, Alessandro Sette, William H. Hildebrand, Morten Nielsen and Bjoern Peters

J Immunol February 15, 2016, 196 (4) 1480-1487; DOI: https://doi.org/10.4049/jimmunol.1501721

AUTOIMMUNITY

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C1q Modulates the Response to TLR7 Stimulation by Pristane-Primed Macrophages: Implications for Pristane-Induced Lupus
Francesco Carlucci, Attia Ishaque, Guang Sheng Ling, Marta Szajna, Ann Sandison, Philippe Donatien, H. Terence Cook and Marina Botto

J Immunol February 15, 2016, 196 (4) 1488-1494; DOI: https://doi.org/10.4049/jimmunol.1401009
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Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes
Ilian A. Radichev, Lilia V. Maneva-Radicheva, Christina Amatya, Maryam Salehi, Camille Parker, Jacob Ellefson, Paul Burn and Alexei Y. Savinov

J Immunol February 15, 2016, 196 (4) 1495-1506; DOI: https://doi.org/10.4049/jimmunol.1403251
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Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus
Simanta Pathak, Kirthi Raman Kumar, Hasna Kanta, Ferdicia Carr-Johnson, Jie Han, Anna Bashmakov, Lionel Faure, Huihua Ding, Kamala Vanarsa, Shaheen Khan, Quan-Zhen Li, Kent Chapman, Edward K. Wakeland and Chandra Mohan

J Immunol February 15, 2016, 196 (4) 1507-1516; DOI: https://doi.org/10.4049/jimmunol.1500291
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γδ T Cells Protect the Liver and Lungs of Mice from Autoimmunity Induced by Scurfy Lymphocytes
Hideyuki Ujiie and Ethan M. Shevach

J Immunol February 15, 2016, 196 (4) 1517-1528; DOI: https://doi.org/10.4049/jimmunol.1501774
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CTL-Promoting Effects of IL-21 Counteract Murine Lupus in the Parent→F1 Graft-versus-Host Disease Model
Vinh Nguyen, Horea Rus, Ching Chen and Violeta Rus

J Immunol February 15, 2016, 196 (4) 1529-1540; DOI: https://doi.org/10.4049/jimmunol.1501824
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Autoreactive CD19⁺CD20⁻ Plasma Cells Contribute to Disease Severity of Experimental Autoimmune Encephalomyelitis
Ding Chen, Sara J. Ireland, Laurie S. Davis, Xiangmei Kong, Ann M. Stowe, Yue Wang, Wendy I. White, Ronald Herbst and Nancy L. Monson

J Immunol February 15, 2016, 196 (4) 1541-1549; DOI: https://doi.org/10.4049/jimmunol.1501376
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Gut Microbiota Regulates K/BxN Autoimmune Arthritis through Follicular Helper T but Not Th17 Cells
Katharine E. Block, Zhong Zheng, Alexander L. Dent, Barbara L. Kee and Haochu Huang

J Immunol February 15, 2016, 196 (4) 1550-1557; DOI: https://doi.org/10.4049/jimmunol.1501904

CLINICAL AND HUMAN IMMUNOLOGY

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Pivotal Role for CD16⁺ Monocytes in Immune Surveillance of the Central Nervous System
Anne Waschbisch, Sina Schröder, Dana Schraudner, Laura Sammet, Babette Weksler, Arthur Melms, Sabine Pfeifenbring, Christine Stadelmann, Stefan Schwab and Ralf A. Linker

J Immunol February 15, 2016, 196 (4) 1558-1567; DOI: https://doi.org/10.4049/jimmunol.1501960
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Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8⁺ Memory Stem Cells in Acquired Aplastic Anemia
Kohei Hosokawa, Pawel Muranski, Xingmin Feng, Danielle M. Townsley, Baoying Liu, Jared Knickelbein, Keyvan Keyvanfar, Bogdan Dumitriu, Sawa Ito, Sachiko Kajigaya, James G. Taylor VI, Mariana J. Kaplan, Robert B. Nussenblatt, A. John Barrett, John O’Shea and Neal S. Young

J Immunol February 15, 2016, 196 (4) 1568-1578; DOI: https://doi.org/10.4049/jimmunol.1501739
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S1PR4 Signaling Attenuates ILT 7 Internalization To Limit IFN-α Production by Human Plasmacytoid Dendritic Cells
Christina Dillmann, Christian Ringel, Julia Ringleb, Javier Mora, Catherine Olesch, Annika F. Fink, Edward Roberts, Bernhard Brüne and Andreas Weigert

J Immunol February 15, 2016, 196 (4) 1579-1590; DOI: https://doi.org/10.4049/jimmunol.1403168

IMMUNE REGULATION

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IL-4 Inhibits the Biogenesis of an Epigenetically Suppressive PIWI-Interacting RNA To Upregulate CD1a Molecules on Monocytes/Dendritic Cells
Xue Zhang, Xin He, Chao Liu, Jun Liu, Qifei Hu, Ting Pan, Xiaobing Duan, Bingfeng Liu, Yiwen Zhang, Jingliang Chen, Xingru Ma, Xu Zhang, Haihua Luo and Hui Zhang

J Immunol February 15, 2016, 196 (4) 1591-1603; DOI: https://doi.org/10.4049/jimmunol.1500805
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The Neonatal CD8⁺ T Cell Repertoire Rapidly Diversifies during Persistent Viral Infection
Vanessa Venturi, Kito Nzingha, Timothy G. Amos, Wisler C. Charles, Iryna Dekhtiarenko, Luka Cicin-Sain, Miles P. Davenport and Brian D. Rudd

J Immunol February 15, 2016, 196 (4) 1604-1616; DOI: https://doi.org/10.4049/jimmunol.1501867
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Hepatic Stellate Cells Directly Inhibit B Cells via Programmed Death–Ligand 1
Yan Li, Lina Lu, Shiguang Qian, John J. Fung and Feng Lin

J Immunol February 15, 2016, 196 (4) 1617-1625; DOI: https://doi.org/10.4049/jimmunol.1501737
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Allergy-Protective Arabinogalactan Modulates Human Dendritic Cells via C-Type Lectins and Inhibition of NF-κB
Marcus Peters, Patrick M. Guidato, Karin Peters, Dominik A. Megger, Barbara Sitek, Birgit Classen, Esther M. Heise and Albrecht Bufe

J Immunol February 15, 2016, 196 (4) 1626-1635; DOI: https://doi.org/10.4049/jimmunol.1502178
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CD46 Activation Regulates miR-150–Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4⁺ T Cells
Ben C. King, Jonathan L. S. Esguerra, Ewelina Golec, Lena Eliasson, Claudia Kemper and Anna M. Blom

J Immunol February 15, 2016, 196 (4) 1636-1645; DOI: https://doi.org/10.4049/jimmunol.1500516
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Ecdysone Titer Determined by 3DE-3β-Reductase Enhances the Immune Response in the Silkworm
Wei Sun, Yi-Hong Shen, Liang-Xiao Zhou and Ze Zhang

J Immunol February 15, 2016, 196 (4) 1646-1654; DOI: https://doi.org/10.4049/jimmunol.1500158

IMMUNE SYSTEM DEVELOPMENT

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Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in Mice
Karin von Wnuck Lipinski, Katherine Sattler, Susann Peters, Sarah Weske, Petra Keul, Hannes Klump, Gerd Heusch, Joachim R. Göthert and Bodo Levkau

J Immunol February 15, 2016, 196 (4) 1655-1665; DOI: https://doi.org/10.4049/jimmunol.1500897
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IRF4 and IRF8 Act in CD11c⁺ Cells To Regulate Terminal Differentiation of Lung Tissue Dendritic Cells
Sandra Bajaña, Sean Turner, Jinny Paul, Erola Ainsua-Enrich and Susan Kovats

J Immunol February 15, 2016, 196 (4) 1666-1677; DOI: https://doi.org/10.4049/jimmunol.1501870
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Kras Is Critical for B Cell Lymphopoiesis
Yuhong Chen, Yongwei Zheng, Xiaona You, Mei Yu, Guoping Fu, Xinlin Su, Fen Zhou, Wen Zhu, Zhihong Wu, Jing Zhang, Renren Wen and Demin Wang

J Immunol February 15, 2016, 196 (4) 1678-1685; DOI: https://doi.org/10.4049/jimmunol.1502112

IMMUNOGENETICS

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Essential Roles of TIM-1 and TIM-4 Homologs in Adaptive Humoral Immunity in a Zebrafish Model
Xiao-gang Xu, Jing-fang Hu, Jun-xia Ma, Li Nie, Tong Shao, Li-xin Xiang and Jian-zhong Shao

J Immunol February 15, 2016, 196 (4) 1686-1699; DOI: https://doi.org/10.4049/jimmunol.1501736

IMMUNOTHERAPY AND VACCINES

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Vaccine Induction of Lymph Node–Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques
Diego A. Vargas-Inchaustegui, Andrew Demers, Julia M. Shaw, Guobin Kang, David Ball, Iskra Tuero, Thomas Musich, Venkatramanan Mohanram, Thorsten Demberg, Tatiana S. Karpova, Qingsheng Li and Marjorie Robert-Guroff

J Immunol February 15, 2016, 196 (4) 1700-1710; DOI: https://doi.org/10.4049/jimmunol.1502137
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Long-Peptide Cross-Presentation by Human Dendritic Cells Occurs in Vacuoles by Peptide Exchange on Nascent MHC Class I Molecules
Wenbin Ma, Yi Zhang, Nathalie Vigneron, Vincent Stroobant, Kris Thielemans, Pierre van der Bruggen and Benoît J. Van den Eynde

J Immunol February 15, 2016, 196 (4) 1711-1720; DOI: https://doi.org/10.4049/jimmunol.1501574
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A Recombinant G Protein Plus Cyclosporine A–Based Respiratory Syncytial Virus Vaccine Elicits Humoral and Regulatory T Cell Responses against Infection without Vaccine-Enhanced Disease
Chaofan Li, Xian Zhou, Yiwei Zhong, Changgui Li, Aihua Dong, Zhonghuai He, Shuren Zhang and Bin Wang

J Immunol February 15, 2016, 196 (4) 1721-1731; DOI: https://doi.org/10.4049/jimmunol.1502103
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A Novel Factor H–Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae
Jutamas Shaughnessy, Sunita Gulati, Sarika Agarwal, Magnus Unemo, Makoto Ohnishi, Xia-Hong Su, Brian G. Monks, Alberto Visintin, Guillermo Madico, Lisa A. Lewis, Douglas T. Golenbock, George W. Reed, Peter A. Rice and Sanjay Ram

J Immunol February 15, 2016, 196 (4) 1732-1740; DOI: https://doi.org/10.4049/jimmunol.1500292
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In Vivo Synthesis of Cyclic-di-GMP Using a Recombinant Adenovirus Preferentially Improves Adaptive Immune Responses against Extracellular Antigens
Fadel S. Alyaqoub, Yasser A. Aldhamen, Benjamin J. Koestler, Eric L. Bruger, Sergey S. Seregin, Cristiane Pereira-Hicks, Sarah Godbehere, Christopher M. Waters and Andrea Amalfitano

J Immunol February 15, 2016, 196 (4) 1741-1752; DOI: https://doi.org/10.4049/jimmunol.1501272

INFECTIOUS DISEASE AND HOST RESPONSE

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NK Cell–Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation
Alaa Kassim Ali, Jun Seok Oh, Eric Vivier, Meinrad Busslinger and Seung-Hwan Lee

J Immunol February 15, 2016, 196 (4) 1753-1767; DOI: https://doi.org/10.4049/jimmunol.1501593
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HIV-1 Env Glycoprotein Phenotype along with Immune Activation Determines CD4 T Cell Loss in HIV Patients
Anjali Joshi, Melina Sedano, Bethany Beauchamp, Erin B. Punke, Zuber D. Mulla, Armando Meza, Ogechika K. Alozie, Debabrata Mukherjee and Himanshu Garg

J Immunol February 15, 2016, 196 (4) 1768-1779; DOI: https://doi.org/10.4049/jimmunol.1501588
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Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity
Sukumar Kandasamy, Anastasia N. Vlasova, David Fischer, Anand Kumar, Kuldeep S. Chattha, Abdul Rauf, Lulu Shao, Stephanie N. Langel, Gireesh Rajashekara and Linda J. Saif

J Immunol February 15, 2016, 196 (4) 1780-1789; DOI: https://doi.org/10.4049/jimmunol.1501705
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TLR-Activated Gap Junction Channels Protect Mice against Bacterial Infection through Extracellular UDP Release
Juliang Qin, Guangxu Zhang, Xiaoyu Zhang, Binghe Tan, Zhangsheng Lv, Mingyao Liu, Hua Ren, Min Qian and Bing Du

J Immunol February 15, 2016, 196 (4) 1790-1798; DOI: https://doi.org/10.4049/jimmunol.1501629
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Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection
Lin Zhang, William K. K. Wu, Richard L. Gallo, Evandro F. Fang, Wei Hu, Thomas K. W. Ling, Jing Shen, Ruby L. Y. Chan, Lan Lu, Xiao M. Luo, Ming X. Li, Kam M. Chan, Jun Yu, Vincent W. S. Wong, Siew C. Ng, Sunny H. Wong, Francis K. L. Chan, Joseph J. Y. Sung, Matthew T. V. Chan and Chi H. Cho

J Immunol February 15, 2016, 196 (4) 1799-1809; DOI: https://doi.org/10.4049/jimmunol.1500021
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Local GM-CSF–Dependent Differentiation and Activation of Pulmonary Dendritic Cells and Macrophages Protect against Progressive Cryptococcal Lung Infection in Mice
Gwo-Hsiao Chen, Seagal Teitz-Tennenbaum, Lori M. Neal, Benjamin J. Murdock, Antoni N. Malachowski, Anthony J. Dils, Michal A. Olszewski and John J. Osterholzer

J Immunol February 15, 2016, 196 (4) 1810-1821; DOI: https://doi.org/10.4049/jimmunol.1501512
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Multiple Inflammatory Cytokines Converge To Regulate CD8⁺ T Cell Expansion and Function during Tuberculosis
Matthew G. Booty, Cláudio Nunes-Alves, Stephen M. Carpenter, Pushpa Jayaraman and Samuel M. Behar

J Immunol February 15, 2016, 196 (4) 1822-1831; DOI: https://doi.org/10.4049/jimmunol.1502206
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Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages
Michihiro Hashimoto, Farzana Bhuyan, Masateru Hiyoshi, Osamu Noyori, Hesham Nasser, Mitsue Miyazaki, Tamio Saito, Yasumitsu Kondoh, Hiroyuki Osada, Shunsuke Kimura, Koji Hase, Hiroshi Ohno and Shinya Suzu

J Immunol February 15, 2016, 196 (4) 1832-1841; DOI: https://doi.org/10.4049/jimmunol.1500845
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Swift and Strong NK Cell Responses Protect 129 Mice against High-Dose Influenza Virus Infection
Kai Zhou, Jing Wang, An Li, Wenming Zhao, Dongfang Wang, Wei Zhang, Jinghua Yan, George Fu Gao, Wenjun Liu and Min Fang

J Immunol February 15, 2016, 196 (4) 1842-1854; DOI: https://doi.org/10.4049/jimmunol.1501486
Open Access
Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination
Author Choice Article

Brett S. Marro, Jonathan J. Grist and Thomas E. Lane

J Immunol February 15, 2016, 196 (4) 1855-1864; DOI: https://doi.org/10.4049/jimmunol.1501802
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Degranulating Neutrophils Promote Leukotriene B₄ Production by Infected Macrophages To Kill Leishmania amazonensis Parasites
Natália Tavares, Lilian Afonso, Martha Suarez, Mariana Ampuero, Deboraci Brito Prates, Théo Araújo-Santos, Manoel Barral-Netto, George A. DosReis, Valéria Matos Borges and Cláudia Brodskyn

J Immunol February 15, 2016, 196 (4) 1865-1873; DOI: https://doi.org/10.4049/jimmunol.1502224

INNATE IMMUNITY AND INFLAMMATION

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Depletion of CD8⁺ T Cells Exacerbates CD4⁺ T Cell–Induced Monocyte-to-Fibroblast Transition in Renal Fibrosis
Yanjun Dong, Min Yang, Jing Zhang, Xiaogang Peng, Jizhong Cheng, Taigeng Cui and Jie Du

J Immunol February 15, 2016, 196 (4) 1874-1881; DOI: https://doi.org/10.4049/jimmunol.1501232
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Pro- and Anti-Inflammatory Role of ChemR23 Signaling in Pollutant-Induced Inflammatory Lung Responses
Sharen Provoost, Katrien C. De Grove, Graeme L. Fraser, Vincent J. Lannoy, Kurt G. Tournoy, Guy G. Brusselle, Tania Maes and Guy F. Joos

J Immunol February 15, 2016, 196 (4) 1882-1890; DOI: https://doi.org/10.4049/jimmunol.1501113
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p52 Overexpression Increases Epithelial Apoptosis, Enhances Lung Injury, and Reduces Survival after Lipopolysaccharide Treatment
Jamie A. Saxon, Dong-Sheng Cheng, Wei Han, Vasiliy V. Polosukhin, Allyson G. McLoed, Bradley W. Richmond, Linda A. Gleaves, Harikrishna Tanjore, Taylor P. Sherrill, Whitney Barham, Fiona E. Yull and Timothy S. Blackwell

J Immunol February 15, 2016, 196 (4) 1891-1899; DOI: https://doi.org/10.4049/jimmunol.1501555
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CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells
Monica Macal, Miguel A. Tam, Charles Hesser, Jeremy Di Domizio, Psylvia Leger, Michel Gilliet and Elina I. Zuniga

J Immunol February 15, 2016, 196 (4) 1900-1909; DOI: https://doi.org/10.4049/jimmunol.1501658
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Galectin-1 Couples Glycobiology to Inflammation in Osteoarthritis through the Activation of an NF-κB–Regulated Gene Network
Stefan Toegel, Daniela Weinmann, Sabine André, Sonja M. Walzer, Martin Bilban, Sebastian Schmidt, Catharina Chiari, Reinhard Windhager, Christoph Krall, Idriss M. Bennani-Baiti and Hans-Joachim Gabius

J Immunol February 15, 2016, 196 (4) 1910-1921; DOI: https://doi.org/10.4049/jimmunol.1501165
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Proresolving Actions of Synthetic and Natural Protease Inhibitors Are Mediated by Annexin A1
Juliana P. Vago, Luciana P. Tavares, Michelle A. Sugimoto, Graziele Letícia N. Lima, Izabela Galvão, Thais R. de Caux, Kátia M. Lima, Ana Luíza C. Ribeiro, Fernanda S. Carneiro, Fernanda Freire C. Nunes, Vanessa Pinho, Mauro Perretti, Mauro M. Teixeira and Lirlândia P. Sousa

J Immunol February 15, 2016, 196 (4) 1922-1932; DOI: https://doi.org/10.4049/jimmunol.1500886

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Molecular Analysis of Lipid-Reactive Vδ1 γδ T Cells Identified by CD1c Tetramers
Sobhan Roy, Dalam Ly, Caitlin D. Castro, Nan-Sheng Li, Andrew J. Hawk, John D. Altman, Stephen C. Meredith, Joseph A. Piccirilli, D. Branch Moody and Erin J. Adams

J Immunol February 15, 2016, 196 (4) 1933-1942; DOI: https://doi.org/10.4049/jimmunol.1502202
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Structural Illumination of Equine MHC Class I Molecules Highlights Unconventional Epitope Presentation Manner That Is Evolved in Equine Leukocyte Antigen Alleles
Shugang Yao, Jun Liu, Jianxun Qi, Rong Chen, Nianzhi Zhang, Yanjie Liu, Junya Wang, Yanan Wu, George Fu Gao and Chun Xia

J Immunol February 15, 2016, 196 (4) 1943-1954; DOI: https://doi.org/10.4049/jimmunol.1501352
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Phosphatidylinositol 4-Phosphate 5-Kinase β Controls Recruitment of Lipid Rafts into the Immunological Synapse
Marinos Kallikourdis, Anna Elisa Trovato, Giuliana Roselli, Michela Muscolini, Nicla Porciello, Loretta Tuosto and Antonella Viola

J Immunol February 15, 2016, 196 (4) 1955-1963; DOI: https://doi.org/10.4049/jimmunol.1501788

TUMOR IMMUNOLOGY

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Low-Intensity Focused Ultrasound Induces Reversal of Tumor-Induced T Cell Tolerance and Prevents Immune Escape
Sanmay Bandyopadhyay, Thomas J. Quinn, Lisa Scandiuzzi, Indranil Basu, Ari Partanen, Wolfgang A. Tomé, Fernando Macian and Chandan Guha

J Immunol February 15, 2016, 196 (4) 1964-1976; DOI: https://doi.org/10.4049/jimmunol.1500541

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Table of Contents

IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

ALLERGY AND OTHER HYPERSENSITIVITIES

ANTIGEN RECOGNITION AND RESPONSES

AUTOIMMUNITY

CLINICAL AND HUMAN IMMUNOLOGY

IMMUNE REGULATION

IMMUNE SYSTEM DEVELOPMENT

IMMUNOGENETICS

IMMUNOTHERAPY AND VACCINES

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

TUMOR IMMUNOLOGY

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