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The Journal of Immunology

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Table of Contents

January 1, 2016; Volume 196,Issue 1

IN THIS ISSUE

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    In This Issue

    Instigating ILC2 See article p. 45

    γδ T Cells Guide B Cell Homeostasis See article p. 217

    Culture System Supercharges T Cells See article p. 256

    Calprotectin Chelates in Corneas See article p. 336

    TB or Not TB Presented See article p. 357

    J Immunol January 1, 2016, 196 (1) 1-2; DOI: https://doi.org/10.4049/jimmunol.1590026

PILLARS OF IMMUNOLOGY

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    CCR7: Unifying Disparate Journeys to the Lymph Node
    Gwendalyn J. Randolph
    J Immunol January 1, 2016, 196 (1) 3-4; DOI: https://doi.org/10.4049/jimmunol.1502372
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    Pillars Article: CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs. Cell. 1999. 99: 23–33
    Reinhold Förster, Andreas Schubel, Dagmar Breitfeld, Elisabeth Kremmer, Ingrid Renner-Müller, Eckhard Wolf and Martin Lipp
    J Immunol January 1, 2016, 196 (1) 5-15;

BRIEF REVIEWS

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    Hepatocytes as Immunological Agents
    Ian N. Crispe
    J Immunol January 1, 2016, 196 (1) 17-21; DOI: https://doi.org/10.4049/jimmunol.1501668
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    Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation
    Andrew P. Fontenot, Michael T. Falta, John W. Kappler, Shaodong Dai and Amy S. McKee
    J Immunol January 1, 2016, 196 (1) 22-27; DOI: https://doi.org/10.4049/jimmunol.1502011

CUTTING EDGE

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    Cutting Edge: DNA in the Lung Microenvironment during Influenza Virus Infection Tempers Inflammation by Engaging the DNA Sensor AIM2
    Stefan A. Schattgen, Guangping Gao, Evelyn A. Kurt-Jones and Katherine A. Fitzgerald
    J Immunol January 1, 2016, 196 (1) 29-33; DOI: https://doi.org/10.4049/jimmunol.1501048
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    Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage
    Oscar Medina-Contreras, Akihito Harusato, Hikaru Nishio, Kyle L. Flannigan, Vu Ngo, Giovanna Leoni, Philipp-Alexander Neumann, Duke Geem, Loukia N. Lili, Ravisankar A. Ramadas, Benoit Chassaing, Andrew T. Gewirtz, Jacob E. Kohlmeier, Charles A. Parkos, Jennifer E. Towne, Asma Nusrat and Timothy L. Denning
    J Immunol January 1, 2016, 196 (1) 34-38; DOI: https://doi.org/10.4049/jimmunol.1501312
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    Cutting Edge: Nonobese Diabetic Mice Deficient in Chromogranin A Are Protected from Autoimmune Diabetes
    Rocky L. Baker, Brenda Bradley, Timothy A. Wiles, Robin S. Lindsay, Gene Barbour, Thomas Delong, Rachel S. Friedman and Kathryn Haskins
    J Immunol January 1, 2016, 196 (1) 39-43; DOI: https://doi.org/10.4049/jimmunol.1501190

ALLERGY AND OTHER HYPERSENSITIVITIES

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    Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production
    Maryam Salimi, Luzheng Xue, Helen Jolin, Clare Hardman, David J. Cousins, Andrew N. J. McKenzie and Graham S. Ogg
    J Immunol January 1, 2016, 196 (1) 45-54; DOI: https://doi.org/10.4049/jimmunol.1501102
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    Bidirectional Counterregulation of Human Lung Mast Cell and Airway Smooth Muscle β2 Adrenoceptors
    Rebecca J. Lewis, Latifa Chachi, Chris Newby, Yassine Amrani and Peter Bradding
    J Immunol January 1, 2016, 196 (1) 55-63; DOI: https://doi.org/10.4049/jimmunol.1402232

ANTIGEN RECOGNITION AND RESPONSES

  • Open Access
    The Tumor Antigen NY-ESO-1 Mediates Direct Recognition of Melanoma Cells by CD4+ T Cells after Intercellular Antigen Transfer

    Author Choice Article

    Jean Francois Fonteneau, Fabienne Brilot, Christian Münz and Monique Gannagé
    J Immunol January 1, 2016, 196 (1) 64-71; DOI: https://doi.org/10.4049/jimmunol.1402664

AUTOIMMUNITY

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    Acid Sphingomyelinase–Derived Ceramide Regulates ICAM-1 Function during T Cell Transmigration across Brain Endothelial Cells
    Melissa A. Lopes Pinheiro, Jeffrey Kroon, Mark Hoogenboezem, Dirk Geerts, Bert van het Hof, Susanne M. A. van der Pol, Jaap D. van Buul and Helga E. de Vries
    J Immunol January 1, 2016, 196 (1) 72-79; DOI: https://doi.org/10.4049/jimmunol.1500702
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    Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus
    Yiming Yin, Seung-Chul Choi, Zhiwei Xu, Leilani Zeumer, Nathalie Kanda, Byron P. Croker and Laurence Morel
    J Immunol January 1, 2016, 196 (1) 80-90; DOI: https://doi.org/10.4049/jimmunol.1501537

CLINICAL AND HUMAN IMMUNOLOGY

  • Open Access
    The Expression of BAFF Is Controlled by IRF Transcription Factors

    Author Choice Article

    Maria Sjöstrand, Alina Johansson, Lara Aqrawi, Tomas Olsson, Marie Wahren-Herlenius and Alexander Espinosa
    J Immunol January 1, 2016, 196 (1) 91-96; DOI: https://doi.org/10.4049/jimmunol.1501061
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    Progression from Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis Is Marked by a Higher Frequency of Th17 Cells in the Liver and an Increased Th17/Resting Regulatory T Cell Ratio in Peripheral Blood and in the Liver
    Monika Rau, Anne-Kristin Schilling, Jan Meertens, Ilona Hering, Johannes Weiss, Christian Jurowich, Theodor Kudlich, Heike M. Hermanns, Heike Bantel, Niklas Beyersdorf and Andreas Geier
    J Immunol January 1, 2016, 196 (1) 97-105; DOI: https://doi.org/10.4049/jimmunol.1501175
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    The Immune-Metabolic Basis of Effector Memory CD4+ T Cell Function under Hypoxic Conditions
    Sarah Dimeloe, Matthias Mehling, Corina Frick, Jordan Loeliger, Glenn R. Bantug, Ursula Sauder, Marco Fischer, Réka Belle, Leyla Develioglu, Savaş Tay, Anja Langenkamp and Christoph Hess
    J Immunol January 1, 2016, 196 (1) 106-114; DOI: https://doi.org/10.4049/jimmunol.1501766
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    Monocyte Stabilin-1 Suppresses the Activation of Th1 Lymphocytes
    Senthil Palani, Kati Elima, Eeva Ekholm, Sirpa Jalkanen and Marko Salmi
    J Immunol January 1, 2016, 196 (1) 115-123; DOI: https://doi.org/10.4049/jimmunol.1500257

IMMUNE REGULATION

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    Costimulation Endows Immunotherapeutic CD8 T Cells with IL-36 Responsiveness during Aerobic Glycolysis
    Naomi Tsurutani, Payal Mittal, Marie-Clare St. Rose, Soo Mun Ngoi, Julia Svedova, Antoine Menoret, Forrest B. Treadway, Reinhard Laubenbacher, Jenny E. Suárez-Ramírez, Linda S. Cauley, Adam J. Adler and Anthony T. Vella
    J Immunol January 1, 2016, 196 (1) 124-134; DOI: https://doi.org/10.4049/jimmunol.1501217
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    Conserved IL-2Rγc Signaling Mediates Lymphopoiesis in Zebrafish
    Robert Sertori, Clifford Liongue, Faiza Basheer, Kanako L. Lewis, Parisa Rasighaemi, Dennis de Coninck, David Traver and Alister C. Ward
    J Immunol January 1, 2016, 196 (1) 135-143; DOI: https://doi.org/10.4049/jimmunol.1403060
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    Helios Controls a Limited Subset of Regulatory T Cell Functions
    Mathew Sebastian, Maria Lopez-Ocasio, Amina Metidji, Sadiye Amcaoglu Rieder, Ethan M. Shevach and Angela M. Thornton
    J Immunol January 1, 2016, 196 (1) 144-155; DOI: https://doi.org/10.4049/jimmunol.1501704
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    Impaired SNX9 Expression in Immune Cells during Chronic Inflammation: Prognostic and Diagnostic Implications
    Eliran Ish-Shalom, Yaron Meirow, Moshe Sade-Feldman, Julia Kanterman, Lynn Wang, Olga Mizrahi, Yair Klieger and Michal Baniyash
    J Immunol January 1, 2016, 196 (1) 156-167; DOI: https://doi.org/10.4049/jimmunol.1402877
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    Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 Expression
    Joëlle Perez, Boris Dansou, Roxane Hervé, Charlène Levi, Houda Tamouza, Sophie Vandermeersch, Emmanuelle Demey-Thomas, Jean-Philippe Haymann, Lara Zafrani, David Klatzmann, Marie-Christophe Boissier, Emmanuel Letavernier and Laurent Baud
    J Immunol January 1, 2016, 196 (1) 168-181; DOI: https://doi.org/10.4049/jimmunol.1500749
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    Alcohol Consumption Modulates Host Defense in Rhesus Macaques by Altering Gene Expression in Circulating Leukocytes
    Tasha Barr, Thomas Girke, Suhas Sureshchandra, Christina Nguyen, Kathleen Grant and Ilhem Messaoudi
    J Immunol January 1, 2016, 196 (1) 182-195; DOI: https://doi.org/10.4049/jimmunol.1501527
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    IgG-Immune Complexes Promote B Cell Memory by Inducing BAFF
    SunAh Kang, Amanda B. Keener, Shannon Z. Jones, Robert J. Benschop, Alfredo Caro-Maldonado, Jeffrey C. Rathmell, Stephen H. Clarke, Glenn K. Matsushima, Jason K. Whitmire and Barbara J. Vilen
    J Immunol January 1, 2016, 196 (1) 196-206; DOI: https://doi.org/10.4049/jimmunol.1402527
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    GIMAP1 Is Essential for the Survival of Naive and Activated B Cells In Vivo
    Louise M. C. Webb, Preeta Datta, Sarah E. Bell, Daisuke Kitamura, Martin Turner and Geoffrey W. Butcher
    J Immunol January 1, 2016, 196 (1) 207-216; DOI: https://doi.org/10.4049/jimmunol.1501582

IMMUNE SYSTEM DEVELOPMENT

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    γδ T Cells Shape Preimmune Peripheral B Cell Populations
    Yafei Huang, Andrew Getahun, Ryan A. Heiser, Thiago O. Detanico, Katja Aviszus, Greg A. Kirchenbaum, Tamara L. Casper, Chunjian Huang, M. Kemal Aydintug, Simon R. Carding, Koichi Ikuta, Hua Huang, Lawrence J. Wysocki, John C. Cambier, Rebecca L. O’Brien and Willi K. Born
    J Immunol January 1, 2016, 196 (1) 217-231; DOI: https://doi.org/10.4049/jimmunol.1501064
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    Lunatic, Manic, and Radical Fringe Each Promote T and B Cell Development
    Yinghui Song, Vivek Kumar, Hua-Xing Wei, Ju Qiu and Pamela Stanley
    J Immunol January 1, 2016, 196 (1) 232-243; DOI: https://doi.org/10.4049/jimmunol.1402421
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    The DNA Ligase IV Syndrome R278H Mutation Impairs B Lymphopoiesis via Error-Prone Nonhomologous End-Joining
    Jihye Park, Robert S. Welner, Mei-Yee Chan, Logan Troppito, Philipp B. Staber, Daniel G. Tenen and Catherine T. Yan
    J Immunol January 1, 2016, 196 (1) 244-255; DOI: https://doi.org/10.4049/jimmunol.1403099

IMMUNOTHERAPY AND VACCINES

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    Priming of Qualitatively Superior Human Effector CD8+ T Cells Using TLR8 Ligand Combined with FLT3 Ligand
    Anna Lissina, Olivia Briceño, Georgia Afonso, Martin Larsen, Emma Gostick, David A. Price, Roberto Mallone and Victor Appay
    J Immunol January 1, 2016, 196 (1) 256-263; DOI: https://doi.org/10.4049/jimmunol.1501140
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    Activation of the Aryl Hydrocarbon Receptor by 10-Cl-BBQ Prevents Insulitis and Effector T Cell Development Independently of Foxp3+ Regulatory T Cells in Nonobese Diabetic Mice
    Allison K. Ehrlich, Jamie M. Pennington, Xisheng Wang, Diana Rohlman, Sumit Punj, Christiane V. Löhr, Matthew T. Newman, Siva K. Kolluri and Nancy I. Kerkvliet
    J Immunol January 1, 2016, 196 (1) 264-273; DOI: https://doi.org/10.4049/jimmunol.1501789
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    Selective CD28 Antagonist Blunts Memory Immune Responses and Promotes Long-Term Control of Skin Inflammation in Nonhuman Primates
    Nicolas Poirier, Melanie Chevalier, Caroline Mary, Jeremy Hervouet, David Minault, Paul Baker, Simon Ville, Stephanie Le Bas-Bernardet, Nahzli Dilek, Lyssia Belarif, Elisabeth Cassagnau, Linda Scobie, Gilles Blancho and Bernard Vanhove
    J Immunol January 1, 2016, 196 (1) 274-283; DOI: https://doi.org/10.4049/jimmunol.1501810
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    A CpG-Ficoll Nanoparticle Adjuvant for Anthrax Protective Antigen Enhances Immunogenicity and Provides Single-Immunization Protection against Inhaled Anthrax in Monkeys
    Melissa A. Kachura, Colin Hickle, Sariah A. Kell, Atul Sathe, Carlo Calacsan, Radwan Kiwan, Brian Hall, Robert Milley, Gary Ott, Robert L. Coffman, Holger Kanzler and John D. Campbell
    J Immunol January 1, 2016, 196 (1) 284-297; DOI: https://doi.org/10.4049/jimmunol.1501903
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    Nonclassical CD4+CD49b+ Regulatory T Cells as a Better Alternative to Conventional CD4+CD25+ T Cells To Dampen Arthritis Severity
    Rita Vicente, Julie Quentin, Anne-Laure Mausset-Bonnefont, Paul Chuchana, Delphine Martire, Maïlys Cren, Christian Jorgensen and Pascale Louis-Plence
    J Immunol January 1, 2016, 196 (1) 298-309; DOI: https://doi.org/10.4049/jimmunol.1501069
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    A cGAS-Independent STING/IRF7 Pathway Mediates the Immunogenicity of DNA Vaccines
    John J. Suschak, Shixia Wang, Katherine A. Fitzgerald and Shan Lu
    J Immunol January 1, 2016, 196 (1) 310-316; DOI: https://doi.org/10.4049/jimmunol.1501836

INFECTIOUS DISEASE AND HOST RESPONSE

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    Migration of CD8+ T Cells into the Central Nervous System Gives Rise to Highly Potent Anti-HIV CD4dimCD8bright T Cells in a Wnt Signaling–Dependent Manner
    Maureen H. Richards, Srinivas D. Narasipura, Melanie S. Seaton, Victoria Lutgen and Lena Al-Harthi
    J Immunol January 1, 2016, 196 (1) 317-327; DOI: https://doi.org/10.4049/jimmunol.1501394
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    Serum Lipoproteins Are Critical for Pulmonary Innate Defense against Staphylococcus aureus Quorum Sensing
    Brett C. Manifold-Wheeler, Bradley O. Elmore, Kathleen D. Triplett, Moriah J. Castleman, Michael Otto and Pamela R. Hall
    J Immunol January 1, 2016, 196 (1) 328-335; DOI: https://doi.org/10.4049/jimmunol.1501835
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    Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection
    Heather L. Clark, Anupam Jhingran, Yan Sun, Chairut Vareechon, Steven de Jesus Carrion, Eric P. Skaar, Walter J. Chazin, José Antonio Calera, Tobias M. Hohl and Eric Pearlman
    J Immunol January 1, 2016, 196 (1) 336-344; DOI: https://doi.org/10.4049/jimmunol.1502037
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    The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion
    Kevin W. Tosh, Lara Mittereder, Sandra Bonne-Annee, Sara Hieny, Thomas B. Nutman, Steven M. Singer, Alan Sher and Dragana Jankovic
    J Immunol January 1, 2016, 196 (1) 345-356; DOI: https://doi.org/10.4049/jimmunol.1501558
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    Suboptimal Antigen Presentation Contributes to Virulence of Mycobacterium tuberculosis In Vivo
    Patricia S. Grace and Joel D. Ernst
    J Immunol January 1, 2016, 196 (1) 357-364; DOI: https://doi.org/10.4049/jimmunol.1501494
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    Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection
    Darin L. Wiesner, Kyle D. Smith, Dmitri I. Kotov, Judith N. Nielsen, Paul R. Bohjanen and Kirsten Nielsen
    J Immunol January 1, 2016, 196 (1) 365-374; DOI: https://doi.org/10.4049/jimmunol.1501871
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    IL-21 Is Important for Induction of KLRG1+ Effector CD8 T Cells during Acute Intracellular Infection
    Magali M. Moretto and Imtiaz A. Khan
    J Immunol January 1, 2016, 196 (1) 375-384; DOI: https://doi.org/10.4049/jimmunol.1501258
  • Open Access
    The Group B Streptococcus–Secreted Protein CIP Interacts with C4, Preventing C3b Deposition via the Lectin and Classical Complement Pathways

    Author Choice Article

    Giampiero Pietrocola, Simonetta Rindi, Roberto Rosini, Scilla Buccato, Pietro Speziale and Immaculada Margarit
    J Immunol January 1, 2016, 196 (1) 385-394; DOI: https://doi.org/10.4049/jimmunol.1501954

INNATE IMMUNITY AND INFLAMMATION

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    S100A8 Production in CXCR2-Expressing CD11b+Gr-1high Cells Aggravates Hepatitis in Mice Fed a High-Fat and High-Cholesterol Diet
    Kaori Mukai, Takuya Miyagi, Kumiko Nishio, Yoshinobu Yokoyama, Teppei Yoshioka, Yoshinobu Saito, Satoshi Tanaka, Minoru Shigekawa, Takatoshi Nawa, Hayato Hikita, Ryotaro Sakamori, Harumasa Yoshihara, Yasuharu Imai, Naoki Hiramatsu, Tomohide Tatsumi and Tetsuo Takehara
    J Immunol January 1, 2016, 196 (1) 395-406; DOI: https://doi.org/10.4049/jimmunol.1402709
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    The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages
    Kenta Moriwaki, Nivea Farias Luz, Sakthi Balaji, Maria Jose De Rosa, Carey L. O’Donnell, Peter J. Gough, John Bertin, Raymond M. Welsh and Francis Ka-Ming Chan
    J Immunol January 1, 2016, 196 (1) 407-415; DOI: https://doi.org/10.4049/jimmunol.1501662
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    Type I IFN Contributes to the Phenotype of Unc93b1D34A/D34A Mice by Regulating TLR7 Expression in B Cells and Dendritic Cells
    Ryutaro Fukui, Atsuo Kanno and Kensuke Miyake
    J Immunol January 1, 2016, 196 (1) 416-427; DOI: https://doi.org/10.4049/jimmunol.1500071
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    TRPV4 Mechanosensitive Ion Channel Regulates Lipopolysaccharide-Stimulated Macrophage Phagocytosis
    Rachel G. Scheraga, Susamma Abraham, Kathryn A. Niese, Brian D. Southern, Lisa M. Grove, R. Duncan Hite, Christine McDonald, Thomas A. Hamilton and Mitchell A. Olman
    J Immunol January 1, 2016, 196 (1) 428-436; DOI: https://doi.org/10.4049/jimmunol.1501688
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    Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance
    Alexander M. Skeldon, Alexandre Morizot, Todd Douglas, Nicola Santoro, Romy Kursawe, Julia Kozlitina, Sonia Caprio, Wajahat Z. Mehal and Maya Saleh
    J Immunol January 1, 2016, 196 (1) 437-447; DOI: https://doi.org/10.4049/jimmunol.1501529

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Nck Binds to the T Cell Antigen Receptor Using Its SH3.1 and SH2 Domains in a Cooperative Manner, Promoting TCR Functioning
    Pussadee Paensuwan, Frederike A. Hartl, O. Sascha Yousefi, Jatuporn Ngoenkam, Piyamaporn Wipa, Esmeralda Beck-Garcia, Elaine P. Dopfer, Boonruang Khamsri, Donruedee Sanguansermsri, Susana Minguet, Wolfgang W. Schamel and Sutatip Pongcharoen
    J Immunol January 1, 2016, 196 (1) 448-458; DOI: https://doi.org/10.4049/jimmunol.1500958
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    Semaphorin 7A Promotes Chemokine-Driven Dendritic Cell Migration
    Anoek van Rijn, Leonie Paulis, Joost te Riet, Angela Vasaturo, Inge Reinieren-Beeren, Alie van der Schaaf, Arthur J. Kuipers, Luuk P. Schulte, Bart C. Jongbloets, R. Jeroen Pasterkamp, Carl G. Figdor, Annemiek B. van Spriel and Sonja I. Buschow
    J Immunol January 1, 2016, 196 (1) 459-468; DOI: https://doi.org/10.4049/jimmunol.1403096

TRANSPLANTATION

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    Host Foxp3+CD4+ Regulatory T Cells Act as a Negative Regulator of Dendritic Cells in the Peritransplantation Period
    Takayuki Inoue, Kazuhiro Ikegame, Katsuji Kaida, Masaya Okada, Satoshi Yoshihara, Hiroya Tamaki, Yoshihiro Fujimori, Toshihiro Soma and Hiroyasu Ogawa
    J Immunol January 1, 2016, 196 (1) 469-483; DOI: https://doi.org/10.4049/jimmunol.1402950

TUMOR IMMUNOLOGY

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    CD137 Agonist Therapy Can Reprogram Regulatory T Cells into Cytotoxic CD4+ T Cells with Antitumor Activity
    Ilseyar Akhmetzyanova, Gennadiy Zelinskyy, Elisabeth Littwitz-Salomon, Anna Malyshkina, Kirsten K. Dietze, Hendrik Streeck, Sven Brandau and Ulf Dittmer
    J Immunol January 1, 2016, 196 (1) 484-492; DOI: https://doi.org/10.4049/jimmunol.1403039

NOVEL IMMUNOLOGICAL METHODS

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    TCRVγ9 γδ T Cell Response to IL-33: A CD4 T Cell–Dependent Mechanism
    Caroline Duault, Don Marc Franchini, Julien Familliades, Corinne Cayrol, Stéphane Roga, Jean-Philippe Girard, Jean-Jacques Fournié and Mary Poupot
    J Immunol January 1, 2016, 196 (1) 493-502; DOI: https://doi.org/10.4049/jimmunol.1500260

CORRECTIONS

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    Correction: Multiple Cathepsins Promote Pro–IL-1β Synthesis and NLRP3-Mediated IL-1β Activation
    Gregory M. Orlowski, Jeff D. Colbert, Shruti Sharma, Matthew Bogyo, Stephanie A. Robertson and Kenneth L. Rock
    J Immunol January 1, 2016, 196 (1) 503; DOI: https://doi.org/10.4049/jimmunol.1502363
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This Issue

The Journal of Immunology: 196 (1)
The Journal of Immunology
Vol. 196, Issue 1
1 Jan 2016
  • Table of Contents
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  • IN THIS ISSUE
  • PILLARS OF IMMUNOLOGY
  • BRIEF REVIEWS
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
  • ANTIGEN RECOGNITION AND RESPONSES
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNE SYSTEM DEVELOPMENT
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • TRANSPLANTATION
  • TUMOR IMMUNOLOGY
  • NOVEL IMMUNOLOGICAL METHODS
  • CORRECTIONS
  • Highlights
  • Most Cited
  • Most Read
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606