The Journal of Immunology: 194 (3)

February 1, 2015; Volume 194,Issue 3

IN THIS ISSUE

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In This Issue
Driving CARs over the Threshold See article p. 911
Finding Friends for AIRE See article p. 921
Thymocyte Peer Pressure See article p. 1057
One More Reason To Take Your Vitamins See article p. 1090
The Skin-ny on Secondary Lymphoid Organs in Transplantation See article p. 1364

J Immunol February 1, 2015, 194 (3) 845-846; DOI: https://doi.org/10.4049/jimmunol.1490056

PILLARS OF IMMUNOLOGY

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Laying Bare the Nude Mouse Gene
Graham Anderson and Nicholas I. McCarthy

J Immunol February 1, 2015, 194 (3) 847-848; DOI: https://doi.org/10.4049/jimmunol.1403061
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Pillars Article: New Member of the Winged-Helix Protein Family Disrupted In Mouse And Rat Nude Mutations. Nature. 1994. 372: 103-107
Michael Nehls, Dietmar Pfeifer, Michael Schorpp, Hans Hedrich and Thomas Boehm

J Immunol February 1, 2015, 194 (3) 849-853;

BRIEF REVIEWS

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The Acute Respiratory Distress Syndrome: From Mechanism to Translation
SeungHye Han and Rama K. Mallampalli

J Immunol February 1, 2015, 194 (3) 855-860; DOI: https://doi.org/10.4049/jimmunol.1402513

CUTTING EDGE

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Cutting Edge: Maresin-1 Engages Regulatory T Cells To Limit Type 2 Innate Lymphoid Cell Activation and Promote Resolution of Lung Inflammation
Nandini Krishnamoorthy, Patrick R. Burkett, Jesmond Dalli, Raja-Elie E. Abdulnour, Romain Colas, Sesquile Ramon, Richard P. Phipps, Nicos A. Petasis, Vijay K. Kuchroo, Charles N. Serhan and Bruce D. Levy

J Immunol February 1, 2015, 194 (3) 863-867; DOI: https://doi.org/10.4049/jimmunol.1402534
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Cutting Edge: Critical Role for C5aRs in the Development of Septic Lymphopenia in Mice
Jamison J. Grailer, Fatemeh Fattahi, Rachel S. Dick, Firas S. Zetoune and Peter A. Ward

J Immunol February 1, 2015, 194 (3) 868-872; DOI: https://doi.org/10.4049/jimmunol.1401193
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Cutting Edge: AIM2 and Endosomal TLRs Differentially Regulate Arthritis and Autoantibody Production in DNase II–Deficient Mice
Rebecca Baum, Shruti Sharma, Susan Carpenter, Quan-Zhen Li, Patricia Busto, Katherine A. Fitzgerald, Ann Marshak-Rothstein and Ellen M. Gravallese

J Immunol February 1, 2015, 194 (3) 873-877; DOI: https://doi.org/10.4049/jimmunol.1402573
Open Access
Cutting Edge: Epigenetic Regulation of Foxp3 Defines a Stable Population of CD4⁺ Regulatory T Cells in Tumors from Mice and Humans
Author Choice Article

Jeremy D. Waight, Shinji Takai, Bo Marelli, Guozhong Qin, Kenneth W. Hance, Dong Zhang, Robert Tighe, Yan Lan, Kin-Ming Lo, Helen Sabzevari, Robert Hofmeister and Nicholas S. Wilson

J Immunol February 1, 2015, 194 (3) 878-882; DOI: https://doi.org/10.4049/jimmunol.1402725
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Cutting Edge: Progesterone Directly Upregulates Vitamin D Receptor Gene Expression for Efficient Regulation of T Cells by Calcitriol
Shankar Thangamani, Myughoo Kim, Youngmin Son, Xinxin Huang, Heejoo Kim, Jee H. Lee, Jungyoon Cho, Benjamin Ulrich, Hal E. Broxmeyer and Chang H. Kim

J Immunol February 1, 2015, 194 (3) 883-886; DOI: https://doi.org/10.4049/jimmunol.1401923

ALLERGY AND OTHER HYPERSENSITIVITIES

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IL-10 and Regulatory T Cells Cooperate in Allergen-Specific Immunotherapy To Ameliorate Allergic Asthma
Livia Böhm, Joachim Maxeiner, Helen Meyer-Martin, Sebastian Reuter, Susetta Finotto, Matthias Klein, Hansjörg Schild, Edgar Schmitt, Tobias Bopp and Christian Taube

J Immunol February 1, 2015, 194 (3) 887-897; DOI: https://doi.org/10.4049/jimmunol.1401612

ANTIGEN RECOGNITION AND RESPONSES

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Fixed Expression of Single Influenza Virus–Specific TCR Chains Demonstrates the Capacity for TCR α– and β–Chain Diversity in the Face of Peptide–MHC Class I Specificity
E. Bridie Clemens, Peter C. Doherty, Nicole L. La Gruta and Stephen J. Turner

J Immunol February 1, 2015, 194 (3) 898-910; DOI: https://doi.org/10.4049/jimmunol.1401792
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Target Antigen Density Governs the Efficacy of Anti–CD20-CD28-CD3 ζ Chimeric Antigen Receptor–Modified Effector CD8⁺ T Cells
Keisuke Watanabe, Seitaro Terakura, Anton C. Martens, Tom van Meerten, Susumu Uchiyama, Misa Imai, Reona Sakemura, Tatsunori Goto, Ryo Hanajiri, Nobuhiko Imahashi, Kazuyuki Shimada, Akihiro Tomita, Hitoshi Kiyoi, Tetsuya Nishida, Tomoki Naoe and Makoto Murata

J Immunol February 1, 2015, 194 (3) 911-920; DOI: https://doi.org/10.4049/jimmunol.1402346

AUTOIMMUNITY

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Homeodomain-Interacting Protein Kinase 2, a Novel Autoimmune Regulator Interaction Partner, Modulates Promiscuous Gene Expression in Medullary Thymic Epithelial Cells
Kristin Rattay, Janine Claude, Esmail Rezavandy, Sonja Matt, Thomas G. Hofmann, Bruno Kyewski and Jens Derbinski

J Immunol February 1, 2015, 194 (3) 921-928; DOI: https://doi.org/10.4049/jimmunol.1402694

CLINICAL AND HUMAN IMMUNOLOGY

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The V Gene Repertoires of Classical and Atypical Memory B Cells in Malaria-Susceptible West African Children
Severin Zinöcker, Christine E. Schindler, Jeff Skinner, Tobias Rogosch, Michael Waisberg, Jean-Nicolas Schickel, Eric Meffre, Kassoum Kayentao, Aïssata Ongoïba, Boubacar Traoré and Susan K. Pierce

J Immunol February 1, 2015, 194 (3) 929-939; DOI: https://doi.org/10.4049/jimmunol.1402168
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Differential Expression of the Transcription Factor ARID3a in Lupus Patient Hematopoietic Progenitor Cells
Michelle L. Ratliff, Julie M. Ward, Joan T. Merrill, Judith A. James and Carol F. Webb

J Immunol February 1, 2015, 194 (3) 940-949; DOI: https://doi.org/10.4049/jimmunol.1401941
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Combination Therapy with Anti–CTLA-4 and Anti–PD-1 Leads to Distinct Immunologic Changes In Vivo
Rituparna Das, Rakesh Verma, Mario Sznol, Chandra Sekhar Boddupalli, Scott N. Gettinger, Harriet Kluger, Margaret Callahan, Jedd D. Wolchok, Ruth Halaban, Madhav V. Dhodapkar and Kavita M. Dhodapkar

J Immunol February 1, 2015, 194 (3) 950-959; DOI: https://doi.org/10.4049/jimmunol.1401686
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CD26-Mediated Induction of EGR2 and IL-10 as Potential Regulatory Mechanism for CD26 Costimulatory Pathway
Ryo Hatano, Kei Ohnuma, Haruna Otsuka, Eriko Komiya, Izumi Taki, Satoshi Iwata, Nam H. Dang, Ko Okumura and Chikao Morimoto

J Immunol February 1, 2015, 194 (3) 960-972; DOI: https://doi.org/10.4049/jimmunol.1402143
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Sterile DJ_H Rearrangements Reveal that Distance Between Gene Segments on the Human Ig H Chain Locus Influences Their Ability To Rearrange
Tina Østergaard Hansen, Anders Blaabjerg Lange and Torben Barington

J Immunol February 1, 2015, 194 (3) 973-982; DOI: https://doi.org/10.4049/jimmunol.1401443

IMMUNE REGULATION

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Immune Complexes Suppress IFN-γ–Induced Responses in Monocytes by Activating Discrete Members of the SRC Kinase Family
Gunther H. Boekhoudt, Anna G. McGrath, Jennifer F. A. Swisher and Gerald M. Feldman

J Immunol February 1, 2015, 194 (3) 983-989; DOI: https://doi.org/10.4049/jimmunol.1401649
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Modulating DNA Methylation in Activated CD8⁺ T Cells Inhibits Regulatory T Cell–Induced Binding of Foxp3 to the CD8⁺ T Cell IL-2 Promoter
Michelle M. Miller, Nnenna Akaronu, Elizabeth M. Thompson, Sylvia F. Hood and Jonathan E. Fogle

J Immunol February 1, 2015, 194 (3) 990-998; DOI: https://doi.org/10.4049/jimmunol.1401762
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Effector T Cells Boost Regulatory T Cell Expansion by IL-2, TNF, OX40, and Plasmacytoid Dendritic Cells Depending on the Immune Context
Audrey Baeyens, David Saadoun, Fabienne Billiard, Angéline Rouers, Sylvie Grégoire, Bruno Zaragoza, Yenkel Grinberg-Bleyer, Gilles Marodon, Eliane Piaggio and Benoît L. Salomon

J Immunol February 1, 2015, 194 (3) 999-1010; DOI: https://doi.org/10.4049/jimmunol.1400504
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Intestinal Helminths Regulate Lethal Acute Graft-versus-Host Disease and Preserve the Graft-versus-Tumor Effect in Mice
Yue Li, Hung-Lin Chen, Nadine Bannick, Michael Henry, Adrian N. Holm, Ahmed Metwali, Joseph F. Urban Jr., Paul B. Rothman, George J. Weiner, Bruce R. Blazar, David E. Elliott and M. Nedim Ince

J Immunol February 1, 2015, 194 (3) 1011-1020; DOI: https://doi.org/10.4049/jimmunol.1303099
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Chronic Morphine-Induced MicroRNA-124 Promotes Microglial Immunosuppression by Modulating P65 and TRAF6
Shuwei Qiu, Yimin Feng, Gene LeSage, Ying Zhang, Charles Stuart, Lei He, Yi Li, Yi Caudle, Ying Peng and Deling Yin

J Immunol February 1, 2015, 194 (3) 1021-1030; DOI: https://doi.org/10.4049/jimmunol.1400106
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Survival of Human Circulating Antigen-Induced Plasma Cells Is Supported by Plasma Cell–Niche Cytokines and T Follicular Helper Lymphocytes
Ana Ramos-Amaya, Beatriz Rodríguez-Bayona, Rubén López-Blanco, Eloisa Andújar, Mónica Pérez-Alegre, Antonio Campos-Caro and José A. Brieva

J Immunol February 1, 2015, 194 (3) 1031-1038; DOI: https://doi.org/10.4049/jimmunol.1402231
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Temporal Expression of Growth Factors Triggered by Epiregulin Regulates Inflammation Development
Masaya Harada, Daisuke Kamimura, Yasunobu Arima, Hitoshi Kohsaka, Yuji Nakatsuji, Makoto Nishida, Toru Atsumi, Jie Meng, Hidenori Bando, Rajeev Singh, Lavannya Sabharwal, Jing-Jing Jiang, Noriko Kumai, Nobuyuki Miyasaka, Saburo Sakoda, Keiko Yamauchi-Takihara, Hideki Ogura, Toshio Hirano and Masaaki Murakami

J Immunol February 1, 2015, 194 (3) 1039-1046; DOI: https://doi.org/10.4049/jimmunol.1400562
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CD40L Induces Functional Tunneling Nanotube Networks Exclusively in Dendritic Cells Programmed by Mediators of Type 1 Immunity
Colleen R. Zaccard, Simon C. Watkins, Pawel Kalinski, Ronald J. Fecek, Aarika L. Yates, Russell D. Salter, Velpandi Ayyavoo, Charles R. Rinaldo and Robbie B. Mailliard

J Immunol February 1, 2015, 194 (3) 1047-1056; DOI: https://doi.org/10.4049/jimmunol.1401832

IMMUNE SYSTEM DEVELOPMENT

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Stable Interactions and Sustained TCR Signaling Characterize Thymocyte–Thymocyte Interactions that Support Negative Selection
Heather J. Melichar, Jenny O. Ross, Kayleigh T. Taylor and Ellen A. Robey

J Immunol February 1, 2015, 194 (3) 1057-1061; DOI: https://doi.org/10.4049/jimmunol.1400169

IMMUNOGENETICS

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The Human IL-23 Receptor rs11209026 A Allele Promotes the Expression of a Soluble IL-23R–Encoding mRNA Species
Raymond Y. Yu, Jonathan Brazaitis and Grant Gallagher

J Immunol February 1, 2015, 194 (3) 1062-1068; DOI: https://doi.org/10.4049/jimmunol.1401850

IMMUNOTHERAPY AND VACCINES

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Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via Murine or Human XCR1
Evelyn Hartung, Martina Becker, Annabell Bachem, Nele Reeg, Anika Jäkel, Andreas Hutloff, Harald Weber, Christoph Weise, Claudia Giesecke, Volker Henn, Stephanie Gurka, Konstantinos Anastassiadis, Hans W. Mages and Richard A. Kroczek

J Immunol February 1, 2015, 194 (3) 1069-1079; DOI: https://doi.org/10.4049/jimmunol.1401903
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CD8 T Cell Tolerance to a Tumor-Associated Self-Antigen Is Reversed by CD4 T Cells Engineered To Express the Same T Cell Receptor
Author Choice Article

Sara Ghorashian, Pedro Veliça, Ignatius Chua, Anne-Marie McNicol, Ben Carpenter, Angelika Holler, Emma Nicholson, Maryam Ahmadi, Mathias Zech, Shao-An Xue, Wolfgang Uckert, Emma Morris, Ronjon Chakraverty and Hans J. Stauss

J Immunol February 1, 2015, 194 (3) 1080-1089; DOI: https://doi.org/10.4049/jimmunol.1401703

INFECTIOUS DISEASE AND HOST RESPONSE

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The α-Tocopherol Form of Vitamin E Reverses Age-Associated Susceptibility to Streptococcus pneumoniae Lung Infection by Modulating Pulmonary Neutrophil Recruitment
Elsa N. Bou Ghanem, Stacie Clark, Xiaogang Du, Dayong Wu, Andrew Camilli, John M. Leong and Simin N. Meydani

J Immunol February 1, 2015, 194 (3) 1090-1099; DOI: https://doi.org/10.4049/jimmunol.1402401
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A Major Role for Myeloid-Derived Suppressor Cells and a Minor Role for Regulatory T Cells in Immunosuppression during Staphylococcus aureus Infection
Christina Tebartz, Sarah Anita Horst, Tim Sparwasser, Jochen Huehn, Andreas Beineke, Georg Peters and Eva Medina

J Immunol February 1, 2015, 194 (3) 1100-1111; DOI: https://doi.org/10.4049/jimmunol.1400196
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Atg7 Enhances Host Defense against Infection via Downregulation of Superoxide but Upregulation of Nitric Oxide
Xuefeng Li, Yan Ye, Xikun Zhou, Canhua Huang and Min Wu

J Immunol February 1, 2015, 194 (3) 1112-1121; DOI: https://doi.org/10.4049/jimmunol.1401958
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IRAK4 as a Molecular Target in the Amelioration of Innate Immunity–Related Endotoxic Shock and Acute Liver Injury by Chlorogenic Acid
Sun Hong Park, Seung-Il Baek, Jieun Yun, Seungmin Lee, Da Young Yoon, Jae-Kyung Jung, Sang-Hun Jung, Bang Yeon Hwang, Jin Tae Hong, Sang-Bae Han and Youngsoo Kim

J Immunol February 1, 2015, 194 (3) 1122-1130; DOI: https://doi.org/10.4049/jimmunol.1402101
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Diverse Roles for T-bet in the Effector Responses Required for Resistance to Infection
Gretchen Harms Pritchard, Aisling O’Hara Hall, David A. Christian, Sagie Wagage, Qun Fang, Gaia Muallem, Beena John, Arielle Glatman Zaretsky, William G. Dunn, Jacqueline Perrigoue, Steven L. Reiner and Christopher A. Hunter

J Immunol February 1, 2015, 194 (3) 1131-1140; DOI: https://doi.org/10.4049/jimmunol.1401617
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CD8⁺ T Cells Complement Antibodies in Protecting against Yellow Fever Virus
Maria R. Bassi, Michael Kongsgaard, Maria A. Steffensen, Christina Fenger, Michael Rasmussen, Karsten Skjødt, Bente Finsen, Anette Stryhn, Søren Buus, Jan P. Christensen and Allan R. Thomsen

J Immunol February 1, 2015, 194 (3) 1141-1153; DOI: https://doi.org/10.4049/jimmunol.1402605
Open Access
Antibody-Mediated Trapping of Helminth Larvae Requires CD11b and Fcγ Receptor I
Author Choice Article

Julia Esser-von Bieren, Beatrice Volpe, Manuel Kulagin, Duncan B. Sutherland, Romain Guiet, Arne Seitz, Benjamin J. Marsland, J. Sjef Verbeek and Nicola L. Harris

J Immunol February 1, 2015, 194 (3) 1154-1163; DOI: https://doi.org/10.4049/jimmunol.1401645
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Complement Component C5 Recruits Neutrophils in the Absence of C3 during Respiratory Infection with Modified Vaccinia Virus Ankara
Philip J. R. Price, Zoltán Bánki, Angelika Scheideler, Heribert Stoiber, Admar Verschoor, Gerd Sutter and Michael H. Lehmann

J Immunol February 1, 2015, 194 (3) 1164-1168; DOI: https://doi.org/10.4049/jimmunol.1301410

INNATE IMMUNITY AND INFLAMMATION

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TRIF-Dependent Innate Immune Activation Is Critical for Survival to Neonatal Gram-Negative Sepsis
Alex G. Cuenca, Dallas N. Joiner, Lori F. Gentile, Angela L. Cuenca, James L. Wynn, Kindra M. Kelly-Scumpia, Philip O. Scumpia, Kevin E. Behrns, Philip A. Efron, Dina Nacionales, Chao Lui, Shannon M. Wallet, Westley H. Reeves, Clayton E. Mathews and Lyle L. Moldawer

J Immunol February 1, 2015, 194 (3) 1169-1177; DOI: https://doi.org/10.4049/jimmunol.1302676
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Radiation Exposure Induces Inflammasome Pathway Activation in Immune Cells
Veit M. Stoecklein, Akinori Osuka, Shizu Ishikawa, Madeline R. Lederer, Lorenz Wanke-Jellinek and James A. Lederer

J Immunol February 1, 2015, 194 (3) 1178-1189; DOI: https://doi.org/10.4049/jimmunol.1303051
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TLR2 Modulates Antibodies Required for Intestinal Ischemia/Reperfusion-Induced Damage and Inflammation
Michael R. Pope and Sherry D. Fleming

J Immunol February 1, 2015, 194 (3) 1190-1198; DOI: https://doi.org/10.4049/jimmunol.1303124
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A Second Stimulus Required for Enhanced Antifungal Activity of Human Neutrophils in Blood Is Provided by Anaphylatoxin C5a
Kerstin Hünniger, Kristin Bieber, Ronny Martin, Teresa Lehnert, Marc Thilo Figge, Jürgen Löffler, Ren-Feng Guo, Niels C. Riedemann and Oliver Kurzai

J Immunol February 1, 2015, 194 (3) 1199-1210; DOI: https://doi.org/10.4049/jimmunol.1401845
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Neutrophil Priming Occurs in a Sequential Manner and Can Be Visualized in Living Animals by Monitoring IL-1β Promoter Activation
Yi Yao, Hironori Matsushima, Jennifer A. Ohtola, Shuo Geng, Ran Lu and Akira Takashima

J Immunol February 1, 2015, 194 (3) 1211-1224; DOI: https://doi.org/10.4049/jimmunol.1402018
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Zebrafish IRF1 Regulates IFN Antiviral Response through Binding to IFNϕ1 and IFNϕ3 Promoters Downstream of MyD88 Signaling
Hui Feng, Yi-Bing Zhang, Qi-Min Zhang, Zhi Li, Qi-Ya Zhang and Jian-Fang Gui

J Immunol February 1, 2015, 194 (3) 1225-1238; DOI: https://doi.org/10.4049/jimmunol.1402415
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MiR-127 Modulates Macrophage Polarization and Promotes Lung Inflammation and Injury by Activating the JNK Pathway
Hangjie Ying, Yanhua Kang, Hang Zhang, Dongjiu Zhao, Jingyan Xia, Zhe Lu, Huanhuan Wang, Feng Xu and Liyun Shi

J Immunol February 1, 2015, 194 (3) 1239-1251; DOI: https://doi.org/10.4049/jimmunol.1402088
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Protective Role for Caspase-11 during Acute Experimental Murine Colitis
Author Choice Article

Katarzyna Oficjalska, Mathilde Raverdeau, Gabriella Aviello, Siobhan C. Wade, Ana Hickey, Katherine M. Sheehan, Sinead C. Corr, Elaine W. Kay, Luke A. O’Neill, Kingston H. G. Mills and Emma M. Creagh

J Immunol February 1, 2015, 194 (3) 1252-1260; DOI: https://doi.org/10.4049/jimmunol.1400501
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Apoptosis-Associated Speck-like Protein Containing a CARD Forms Specks but Does Not Activate Caspase-1 in the Absence of NLRP3 during Macrophage Swelling
Vincent Compan, Fátima Martín-Sánchez, Alberto Baroja-Mazo, Gloria López-Castejón, Ana I. Gomez, Alexei Verkhratsky, David Brough and Pablo Pelegrín

J Immunol February 1, 2015, 194 (3) 1261-1273; DOI: https://doi.org/10.4049/jimmunol.1301676
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Endogenous Intracellular Cathelicidin Enhances TLR9 Activation in Dendritic Cells and Macrophages
Yukinobu Nakagawa and Richard L. Gallo

J Immunol February 1, 2015, 194 (3) 1274-1284; DOI: https://doi.org/10.4049/jimmunol.1402388
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Complement Deficiency Promotes Cutaneous Wound Healing in Mice
Stavros Rafail, Ioannis Kourtzelis, Periklis G. Foukas, Maciej M. Markiewski, Robert A. DeAngelis, Mara Guariento, Daniel Ricklin, Elizabeth A. Grice and John D. Lambris

J Immunol February 1, 2015, 194 (3) 1285-1291; DOI: https://doi.org/10.4049/jimmunol.1402354
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The Endoplasmic Reticulum Adaptor Protein ERAdP Initiates NK Cell Activation via the Ubc13-Mediated NF-κB Pathway
Jun Chen, Lu Hao, Chong Li, Buqing Ye, Ying Du, Honglian Zhang, Bo Long, Pingping Zhu, Benyu Liu, Liuliu Yang, Peifeng Li, Yong Tian and Zusen Fan

J Immunol February 1, 2015, 194 (3) 1292-1303; DOI: https://doi.org/10.4049/jimmunol.1402593
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Distinct Cellular Sources of Hepoxilin A₃ and Leukotriene B₄ Are Used To Coordinate Bacterial-Induced Neutrophil Transepithelial Migration
Michael A. Pazos, Waheed Pirzai, Lael M. Yonker, Christophe Morisseau, Karsten Gronert and Bryan P. Hurley

J Immunol February 1, 2015, 194 (3) 1304-1315; DOI: https://doi.org/10.4049/jimmunol.1402489
Open Access
Knockdown of the Antiapoptotic Bcl-2 Family Member A1/Bfl-1 Protects Mice from Anaphylaxis
Author Choice Article

Eleonora Ottina, Katarina Lyberg, Maja Sochalska, Andreas Villunger and Gunnar P. Nilsson

J Immunol February 1, 2015, 194 (3) 1316-1322; DOI: https://doi.org/10.4049/jimmunol.1400637

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Phosphatidylinositol 4–Phosphate 5–Kinase α and Vav1 Mutual Cooperation in CD28-Mediated Actin Remodeling and Signaling Functions
Michela Muscolini, Cristina Camperio, Nicla Porciello, Silvana Caristi, Cristina Capuano, Antonella Viola, Ricciarda Galandrini and Loretta Tuosto

J Immunol February 1, 2015, 194 (3) 1323-1333; DOI: https://doi.org/10.4049/jimmunol.1401643

MUCOSAL IMMUNOLOGY

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IL-2Rβ–Dependent Signaling and CD103 Functionally Cooperate To Maintain Tolerance in the Gut Mucosa
Xiaomei Yuan, Michael J. Dee, Norman H. Altman and Thomas R. Malek

J Immunol February 1, 2015, 194 (3) 1334-1346; DOI: https://doi.org/10.4049/jimmunol.1400955

TRANSPLANTATION

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IFN-γ Production by Memory Helper T Cells Is Required for CD40-Independent Alloantibody Responses
Victoria Gorbacheva, Ran Fan, Xi Wang, William M. Baldwin III, Robert L. Fairchild and Anna Valujskikh

J Immunol February 1, 2015, 194 (3) 1347-1356; DOI: https://doi.org/10.4049/jimmunol.1401573
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Anti–IL-12/23 p40 Antibody Attenuates Experimental Chronic Graft-versus-Host Disease via Suppression of IFN-γ/IL-17–Producing Cells
Sachiyo Okamoto, Hideaki Fujiwara, Hisakazu Nishimori, Ken-ichi Matsuoka, Nobuharu Fujii, Eisei Kondo, Takehiro Tanaka, Akihiko Yoshimura, Mitsune Tanimoto and Yoshinobu Maeda

J Immunol February 1, 2015, 194 (3) 1357-1363; DOI: https://doi.org/10.4049/jimmunol.1400973
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Both Rejection and Tolerance of Allografts Can Occur in the Absence of Secondary Lymphoid Tissues
Cavit D. Kant, Yoshinobu Akiyama, Katsunori Tanaka, Susan Shea, Yohei Yamada, Sarah E. Connolly, Jose Marino, Georges Tocco and Gilles Benichou

J Immunol February 1, 2015, 194 (3) 1364-1371; DOI: https://doi.org/10.4049/jimmunol.1401157

NOVEL IMMUNOLOGICAL METHODS

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TSLP Expression: Analysis with a ZsGreen TSLP Reporter Mouse
Cedric Dewas, Xi Chen, Tetsuya Honda, Ilkka Junttila, Jay Linton, Mark C. Udey, Stephen F. Porcella, Daniel E. Sturdevant, Lionel Feigenbaum, Lily Koo, Joy Williams and William E. Paul

J Immunol February 1, 2015, 194 (3) 1372-1380; DOI: https://doi.org/10.4049/jimmunol.1400519

LETTERS OF RETRACTION

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Retraction: Guanosine Inhibits CD40 Receptor Expression and Function Induced by Cytokines and β Amyloid in Mouse Microglia Cells
Iolanda D’Alimonte, Vincenzo Flati, Elena Toniato, Stefano Martinotti, Michel P. Rathbone, Shucui Jiang, Patrizia Di Iorio, Francesco Caciagli and Renata Ciccarelli

J Immunol February 1, 2015, 194 (3) 1381; DOI: https://doi.org/10.4049/jimmunol.1490054

CORRECTIONS

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Correction: Role of Neutrophils in IL-17–Dependent Immunity to Mucosal Candidiasis
Anna R. Huppler, Heather R. Conti, Nydiaris Hernández-Santos, Toni Darville, Partha S. Biswas and Sarah L. Gaffen

J Immunol February 1, 2015, 194 (3) 1382; DOI: https://doi.org/10.4049/jimmunol.1490053
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Correction: AID-Initiated DNA Lesions Are Differentially Processed in Distinct B Cell Populations
Zhangguo Chen, Sheila Ranganath, Sawanee S. Viboolsittiseri, Maxwell D. Eder, Xiaomi Chen, Mihret T. Elos, Shunzong Yuan, Erica Hansen and Jing H. Wang

J Immunol February 1, 2015, 194 (3) 1383; DOI: https://doi.org/10.4049/jimmunol.1490055

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Table of Contents

IN THIS ISSUE

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

ALLERGY AND OTHER HYPERSENSITIVITIES

ANTIGEN RECOGNITION AND RESPONSES

AUTOIMMUNITY

CLINICAL AND HUMAN IMMUNOLOGY

IMMUNE REGULATION

IMMUNE SYSTEM DEVELOPMENT

IMMUNOGENETICS

IMMUNOTHERAPY AND VACCINES

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

MUCOSAL IMMUNOLOGY

TRANSPLANTATION

NOVEL IMMUNOLOGICAL METHODS

LETTERS OF RETRACTION

CORRECTIONS

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