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The Journal of Immunology

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Table of Contents

June 1, 2015; Volume 194,Issue 11

IN THIS ISSUE

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    In This Issue

    IFN Blocks IL-2 Locus Remodeling See article p. 5120

    IL-11 Exacerbates MS Inflammation See article p. 5139

    Evading Immunity with Adenosine See article p. 5312

    All About Autophagy See articles p. 5407 and 5465

    Seeing C4b See article p. 5488

    J Immunol June 1, 2015, 194 (11) 5037-5038; DOI: https://doi.org/10.4049/jimmunol.1590009

LETTERS TO THE EDITOR

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    Comment on “Radiation Exposure Induces Inflammasome Pathway Activation in Immune Cells”
    Yoshiyuki Inoue and Masafumi Takahashi
    J Immunol June 1, 2015, 194 (11) 5039; DOI: https://doi.org/10.4049/jimmunol.1500381
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    Response to Comment on “Radiation Exposure Induces Inflammasome Pathway Activation in Immune Cells”
    James A. Lederer
    J Immunol June 1, 2015, 194 (11) 5039; DOI: https://doi.org/10.4049/jimmunol.1500789

PILLARS OF IMMUNOLOGY

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    Kill or Be Killed
    Edward M. Behrens and Randy Q. Cron
    J Immunol June 1, 2015, 194 (11) 5041-5043; DOI: https://doi.org/10.4049/jimmunol.1500774
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    Pillars Article: Perforin Gene Defects in Familial Hemophagocytic Lymphohistiocytosis. Science. 1999. 286: 1957–1959
    Susan E. Stepp, Rémi Dufourcq-Lagelouse, Françoise Le Deist, Sadhna Bhawan, Stéphanie Certain, Porunelloor A. Mathew, Jan-Inge Henter, Michael Bennett, Alain Fischer, Geneviève de Saint Basile and Vinay Kumar
    J Immunol June 1, 2015, 194 (11) 5044-5046;

BRIEF REVIEWS

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    Prospects for Therapeutic Targeting of MicroRNAs in Human Immunological Diseases
    Marisa E. Luck, Stefan A. Muljo and Colm B. Collins
    J Immunol June 1, 2015, 194 (11) 5047-5052; DOI: https://doi.org/10.4049/jimmunol.1403146
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    The Biology and Disease Relevance of CD300a, an Inhibitory Receptor for Phosphatidylserine and Phosphatidylethanolamine
    Olatz Zenarruzabeitia, Joana Vitallé, Cristina Eguizabal, Venkateswara R. Simhadri and Francisco Borrego
    J Immunol June 1, 2015, 194 (11) 5053-5060; DOI: https://doi.org/10.4049/jimmunol.1500304

ALLERGY AND OTHER HYPERSENSITIVITIES

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    Platelet-Driven Leukotriene C4–Mediated Airway Inflammation in Mice Is Aspirin-Sensitive and Depends on T Prostanoid Receptors
    Tao Liu, Denise Garofalo, Chunli Feng, Juying Lai, Howard Katz, Tanya M. Laidlaw and Joshua A. Boyce
    J Immunol June 1, 2015, 194 (11) 5061-5068; DOI: https://doi.org/10.4049/jimmunol.1402959
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    Involvement of CD300a Phosphatidylserine Immunoreceptor in Aluminum Salt Adjuvant–Induced Th2 Responses
    Haruka Miki, Chigusa Nakahashi-Oda, Takayuki Sumida and Akira Shibuya
    J Immunol June 1, 2015, 194 (11) 5069-5076; DOI: https://doi.org/10.4049/jimmunol.1402915

AUTOIMMUNITY

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    B Cell Antigen Presentation Is Sufficient To Drive Neuroinflammation in an Animal Model of Multiple Sclerosis
    Chelsea R. Parker Harp, Angela S. Archambault, Julia Sim, Stephen T. Ferris, Robert J. Mikesell, Pandelakis A. Koni, Michiko Shimoda, Christopher Linington, John H. Russell and Gregory F. Wu
    J Immunol June 1, 2015, 194 (11) 5077-5084; DOI: https://doi.org/10.4049/jimmunol.1402236
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    Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy
    Javad Rasouli, Bogoljub Ciric, Jaime Imitola, Patricia Gonnella, Daniel Hwang, Kedar Mahajan, Elisabeth R. Mari, Farinaz Safavi, Thomas P. Leist, Guang-Xian Zhang and Abdolmohamad Rostami
    J Immunol June 1, 2015, 194 (11) 5085-5093; DOI: https://doi.org/10.4049/jimmunol.1403243
  • Open Access
    Dual Inhibition of TNFR1 and IFNAR1 in Imiquimod-Induced Psoriasiform Skin Inflammation in Mice

    Author Choice Article

    Lynda Grine, Lien Dejager, Claude Libert and Roosmarijn E. Vandenbroucke
    J Immunol June 1, 2015, 194 (11) 5094-5102; DOI: https://doi.org/10.4049/jimmunol.1403015
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    A Humanized Monoclonal Antibody against Heat Shock Protein 60 Suppresses Murine Arthritis and Colitis and Skews the Cytokine Balance toward an Anti-Inflammatory Response
    Rina Ulmansky, Dorit Landstein, Eli Moallem, Virginie Loeb, Avi Levin, Ronit Meyuhas, Galia Katzavian, Shira Yair and Yaakov Naparstek
    J Immunol June 1, 2015, 194 (11) 5103-5109; DOI: https://doi.org/10.4049/jimmunol.1500023
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    IL-37 Alleviates Rheumatoid Arthritis by Suppressing IL-17 and IL-17–Triggering Cytokine Production and Limiting Th17 Cell Proliferation
    Liang Ye, Bo Jiang, Jun Deng, Jing Du, Wen Xiong, Youfei Guan, Zhongyang Wen, Kunzhao Huang and Zhong Huang
    J Immunol June 1, 2015, 194 (11) 5110-5119; DOI: https://doi.org/10.4049/jimmunol.1401810
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    IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling
    Dennis C. Otero, Nancy J. Fares-Frederickson, Menghong Xiao, Darren P. Baker and Michael David
    J Immunol June 1, 2015, 194 (11) 5120-5128; DOI: https://doi.org/10.4049/jimmunol.1403181
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    Anti–Factor H Autoantibodies in C3 Glomerulopathies and in Atypical Hemolytic Uremic Syndrome: One Target, Two Diseases
    Caroline Blanc, Shambhuprasad Kotresh Togarsimalemath, Sophie Chauvet, Moglie Le Quintrec, Bruno Moulin, Matthias Buchler, T. Sakari Jokiranta, Lubka T. Roumenina, Véronique Fremeaux-Bacchi and Marie-Agnès Dragon-Durey
    J Immunol June 1, 2015, 194 (11) 5129-5138; DOI: https://doi.org/10.4049/jimmunol.1402770

CLINICAL AND HUMAN IMMUNOLOGY

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    IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis
    Xin Zhang, Yazhong Tao, Manisha Chopra, Irena Dujmovic-Basuroski, Jianping Jin, Yunan Tang, Jelena Drulovic and Silva Markovic-Plese
    J Immunol June 1, 2015, 194 (11) 5139-5149; DOI: https://doi.org/10.4049/jimmunol.1401680
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    CD14++CD16+ Monocytes Are Enriched by Glucocorticoid Treatment and Are Functionally Attenuated in Driving Effector T Cell Responses
    Baoying Liu, Ashwin Dhanda, Sima Hirani, Emily L. Williams, H. Nida Sen, Fernando Martinez Estrada, Diamond Ling, Ian Thompson, Megan Casady, Zhiyu Li, Han Si, William Tucker, Lai Wei, Shayma Jawad, Amol Sura, Jennifer Dailey, Susan Hannes, Ping Chen, Jason L. Chien, Siamon Gordon, Richard W. J. Lee and Robert B. Nussenblatt
    J Immunol June 1, 2015, 194 (11) 5150-5160; DOI: https://doi.org/10.4049/jimmunol.1402409
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    Upregulation of the N-Formyl Peptide Receptors in Scleroderma Fibroblasts Fosters the Switch to Myofibroblasts
    Francesca Wanda Rossi, Filomena Napolitano, Ada Pesapane, Massimo Mascolo, Stefania Staibano, Marco Matucci-Cerinic, Serena Guiducci, Pia Ragno, Gaetano di Spigna, Loredana Postiglione, Gianni Marone, Nunzia Montuori and Amato de Paulis
    J Immunol June 1, 2015, 194 (11) 5161-5173; DOI: https://doi.org/10.4049/jimmunol.1402819

IMMUNE REGULATION

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    High Mitochondrial Respiration and Glycolytic Capacity Represent a Metabolic Phenotype of Human Tolerogenic Dendritic Cells
    Frano Malinarich, Kaibo Duan, Raudhah Abdull Hamid, Au Bijin, Wu Xue Lin, Michael Poidinger, Anna-Marie Fairhurst and John E. Connolly
    J Immunol June 1, 2015, 194 (11) 5174-5186; DOI: https://doi.org/10.4049/jimmunol.1303316
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    T Follicular Helper, but Not Th1, Cell Differentiation in the Absence of Conventional Dendritic Cells
    Madelene W. Dahlgren, Tobias Gustafsson-Hedberg, Megan Livingston, Helena Cucak, Samuel Alsén, Ulf Yrlid and Bengt Johansson-Lindbom
    J Immunol June 1, 2015, 194 (11) 5187-5199; DOI: https://doi.org/10.4049/jimmunol.1401938
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    Collecting Lymphatic Vessel Permeability Facilitates Adipose Tissue Inflammation and Distribution of Antigen to Lymph Node–Homing Adipose Tissue Dendritic Cells
    Emma L. Kuan, Stoyan Ivanov, Eric A. Bridenbaugh, Gabriel Victora, Wei Wang, Ed W. Childs, Andrew M. Platt, Claudia V. Jakubzick, Robert J. Mason, Anatoliy A. Gashev, Michel Nussenzweig, Melody A. Swartz, Michael L. Dustin, David C. Zawieja and Gwendalyn J. Randolph
    J Immunol June 1, 2015, 194 (11) 5200-5210; DOI: https://doi.org/10.4049/jimmunol.1500221
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    Critical Role of Mast Cells and Peroxisome Proliferator–Activated Receptor γ in the Induction of Myeloid-Derived Suppressor Cells by Marijuana Cannabidiol In Vivo
    Venkatesh L. Hegde, Udai P. Singh, Prakash S. Nagarkatti and Mitzi Nagarkatti
    J Immunol June 1, 2015, 194 (11) 5211-5222; DOI: https://doi.org/10.4049/jimmunol.1401844
  • Open Access
    The Free Radical Scavenger NecroX-7 Attenuates Acute Graft-versus-Host Disease via Reciprocal Regulation of Th1/Regulatory T Cells and Inhibition of HMGB1 Release

    Author Choice Article

    Keon-Il Im, Nayoun Kim, Jung-Yeon Lim, Young-Sun Nam, Eun-Sol Lee, Eun-Jung Kim, Hyoung Jin Kim, Soon Ha Kim and Seok-Goo Cho
    J Immunol June 1, 2015, 194 (11) 5223-5232; DOI: https://doi.org/10.4049/jimmunol.1402609
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    The Tolerogenic Function of Annexins on Apoptotic Cells Is Mediated by the Annexin Core Domain
    Björn Linke, Lucie Abeler-Dörner, Veronika Jahndel, Alexandra Kurz, Andrea Mahr, Sandra Pfrang, Linda Linke, Peter H. Krammer and Heiko Weyd
    J Immunol June 1, 2015, 194 (11) 5233-5242; DOI: https://doi.org/10.4049/jimmunol.1401299
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    C-Reactive Protein Directly Suppresses Th1 Cell Differentiation and Alleviates Experimental Autoimmune Encephalomyelitis
    Lin Zhang, Shan-Hui Liu, Tyler T. Wright, Zhi-Yuan Shen, Hai-Yun Li, Wei Zhu, Lawrence A. Potempa, Shang-Rong Ji, Alexander J. Szalai and Yi Wu
    J Immunol June 1, 2015, 194 (11) 5243-5252; DOI: https://doi.org/10.4049/jimmunol.1402909
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    Leptin Receptor Signaling in T Cells Is Required for Th17 Differentiation
    Bernardo S. Reis, Kihyun Lee, Melania H. Fanok, Cristina Mascaraque, Manal Amoury, Lillian B. Cohn, Aneta Rogoz, Olof S. Dallner, Pedro M. Moraes-Vieira, Ana I. Domingos and Daniel Mucida
    J Immunol June 1, 2015, 194 (11) 5253-5260; DOI: https://doi.org/10.4049/jimmunol.1402996
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    Altered Connexin 43 Expression Underlies Age-Dependent Decrease of Regulatory T Cell Suppressor Function in Nonobese Diabetic Mice
    Michal Kuczma, Cong-Yi Wang, Leszek Ignatowicz, Robert Gourdie and Piotr Kraj
    J Immunol June 1, 2015, 194 (11) 5261-5271; DOI: https://doi.org/10.4049/jimmunol.1400887

IMMUNE SYSTEM DEVELOPMENT

  • Open Access
    Tumor-Associated and Disease-Associated Autoantibody Repertoires in Healthy Colostrum and Maternal and Newborn Cord Sera

    Author Choice Article

    Asaf Madi, Sharron Bransburg-Zabary, Ayala Maayan-Metzger, Gittit Dar, Eshel Ben-Jacob and Irun R. Cohen
    J Immunol June 1, 2015, 194 (11) 5272-5281; DOI: https://doi.org/10.4049/jimmunol.1402771

IMMUNOTHERAPY AND VACCINES

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    Allogeneic Mature Human Dendritic Cells Generate Superior Alloreactive Regulatory T Cells in the Presence of IL-15
    Nicolle H. R. Litjens, Karin Boer, Joke M. Zuijderwijk, Mariska Klepper, Annemiek M. A. Peeters, Errol P. Prens, Wenda Verschoor, Rens Kraaijeveld, Zeliha Ozgur, Mirjam C. van den Hout-van Vroonhoven, Wilfred F. J. van IJcken, Carla C. Baan and Michiel G. H. Betjes
    J Immunol June 1, 2015, 194 (11) 5282-5293; DOI: https://doi.org/10.4049/jimmunol.1402827
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    Mechanistic Assessment of PD-1H Coinhibitory Receptor–Induced T Cell Tolerance to Allogeneic Antigens
    Dallas B. Flies, Tomoe Higuchi and Lieping Chen
    J Immunol June 1, 2015, 194 (11) 5294-5304; DOI: https://doi.org/10.4049/jimmunol.1402648
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    B7H6-Specific Bispecific T Cell Engagers Lead to Tumor Elimination and Host Antitumor Immunity
    Ming-Ru Wu, Tong Zhang, Albert T. Gacerez, Tiffany A. Coupet, Leslie R. DeMars and Charles L. Sentman
    J Immunol June 1, 2015, 194 (11) 5305-5311; DOI: https://doi.org/10.4049/jimmunol.1402517

INFECTIOUS DISEASE AND HOST RESPONSE

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    Staphylococcus aureus Adenosine Inhibits sPLA2-IIA–Mediated Host Killing in the Airways
    Erwan Pernet, Jérémy Brunet, Laurent Guillemot, Michel Chignard, Lhousseine Touqui and Yongzheng Wu
    J Immunol June 1, 2015, 194 (11) 5312-5319; DOI: https://doi.org/10.4049/jimmunol.1402665
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    Viremic HIV Controllers Exhibit High Plasmacytoid Dendritic Cell–Reactive Opsonophagocytic IgG Antibody Responses against HIV-1 p24 Associated with Greater Antibody Isotype Diversification
    M. Christian Tjiam, James P. A. Taylor, Mazmah A. Morshidi, Lucy Sariputra, Sally Burrows, Jeffrey N. Martin, Steven G. Deeks, Dino B. A. Tan, Silvia Lee, Sonia Fernandez and Martyn A. French
    J Immunol June 1, 2015, 194 (11) 5320-5328; DOI: https://doi.org/10.4049/jimmunol.1402918
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    CD8+ TCR Bias and Immunodominance in HIV-1 Infection
    Henrik N. Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung’u, Søren Buus, David A. Price and Philip J. Goulder
    J Immunol June 1, 2015, 194 (11) 5329-5345; DOI: https://doi.org/10.4049/jimmunol.1400854
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    Early Effector Cells Survive the Contraction Phase in Malaria Infection and Generate Both Central and Effector Memory T Cells
    Michael M. Opata, Victor H. Carpio, Samad A. Ibitokou, Brian E. Dillon, Joshua M. Obiero and Robin Stephens
    J Immunol June 1, 2015, 194 (11) 5346-5354; DOI: https://doi.org/10.4049/jimmunol.1403216
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    MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during Mycobacterial Infection
    Jin Kyung Kim, Jae-Min Yuk, Soo Yeon Kim, Tae Sung Kim, Hyo Sun Jin, Chul-Su Yang and Eun-Kyeong Jo
    J Immunol June 1, 2015, 194 (11) 5355-5365; DOI: https://doi.org/10.4049/jimmunol.1402557

INNATE IMMUNITY AND INFLAMMATION

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    C-Type Lectin Receptor MCL Facilitates Mincle Expression and Signaling through Complex Formation
    Yasunobu Miyake, Masatsugu Oh-hora and Sho Yamasaki
    J Immunol June 1, 2015, 194 (11) 5366-5374; DOI: https://doi.org/10.4049/jimmunol.1402429
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    HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1
    Hao Wang, Ling Bei, Chirag A. Shah, Liping Hu and Elizabeth A. Eklund
    J Immunol June 1, 2015, 194 (11) 5375-5387; DOI: https://doi.org/10.4049/jimmunol.1401909
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    Hypercapnia Inhibits Autophagy and Bacterial Killing in Human Macrophages by Increasing Expression of Bcl-2 and Bcl-xL
    S. Marina Casalino-Matsuda, Aisha Nair, Greg J. Beitel, Khalilah L. Gates and Peter H. S. Sporn
    J Immunol June 1, 2015, 194 (11) 5388-5396; DOI: https://doi.org/10.4049/jimmunol.1500150
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    The Thrombin-Derived Host Defense Peptide GKY25 Inhibits Endotoxin-Induced Responses through Interactions with Lipopolysaccharide and Macrophages/Monocytes
    Finja C. Hansen, Martina Kalle-Brune, Mariena J. A. van der Plas, Ann-Charlotte Strömdahl, Martin Malmsten, Matthias Mörgelin and Artur Schmidtchen
    J Immunol June 1, 2015, 194 (11) 5397-5406; DOI: https://doi.org/10.4049/jimmunol.1403009
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    Critical Role for IL-18 in Spontaneous Lung Inflammation Caused by Autophagy Deficiency
    Elmoataz Abdel Fattah, Abhisek Bhattacharya, Alan Herron, Zeenat Safdar and N. Tony Eissa
    J Immunol June 1, 2015, 194 (11) 5407-5416; DOI: https://doi.org/10.4049/jimmunol.1402277
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    The Processed Amino-Terminal Fragment of Human TLR7 Acts as a Chaperone To Direct Human TLR7 into Endosomes

    Author Choice Article

    Madeleine M. Hipp, Dawn Shepherd, Sarah Booth, Dominic Waithe, Caetano Reis e Sousa and Vincenzo Cerundolo
    J Immunol June 1, 2015, 194 (11) 5417-5425; DOI: https://doi.org/10.4049/jimmunol.1402703
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    Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses
    Toshifumi Kimura, Shota Endo, Masanori Inui, Shin-Ichiroh Saitoh, Kensuke Miyake and Toshiyuki Takai
    J Immunol June 1, 2015, 194 (11) 5426-5436; DOI: https://doi.org/10.4049/jimmunol.1402006
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    miR-155 Deficiency Ameliorates Autoimmune Inflammation of Systemic Lupus Erythematosus by Targeting S1pr1 in Faslpr/lpr Mice
    Qian Xin, Jiangxia Li, Jie Dang, Xianli Bian, Shan Shan, Jupeng Yuan, Yanyan Qian, Zhaojian Liu, Guangyi Liu, Qianqian Yuan, Na Liu, Xiaochun Ma, Fei Gao, Yaoqin Gong and Qiji Liu
    J Immunol June 1, 2015, 194 (11) 5437-5445; DOI: https://doi.org/10.4049/jimmunol.1403028
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    A New Approach for the Treatment of Arthritis in Mice with a Novel Conjugate of an Anti-C5aR1 Antibody and C5 Small Interfering RNA
    Gaurav Mehta, Robert I. Scheinman, V. Michael Holers and Nirmal K. Banda
    J Immunol June 1, 2015, 194 (11) 5446-5454; DOI: https://doi.org/10.4049/jimmunol.1403012
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    Differential Activation of Inflammatory Pathways in Testicular Macrophages Provides a Rationale for Their Subdued Inflammatory Capacity
    Sudhanshu Bhushan, Svetlin Tchatalbachev, Yongning Lu, Suada Fröhlich, Monika Fijak, Vijith Vijayan, Trinad Chakraborty and Andreas Meinhardt
    J Immunol June 1, 2015, 194 (11) 5455-5464; DOI: https://doi.org/10.4049/jimmunol.1401132
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    The Lung Is Protected from Spontaneous Inflammation by Autophagy in Myeloid Cells
    Masashi Kanayama, You-Wen He and Mari L. Shinohara
    J Immunol June 1, 2015, 194 (11) 5465-5471; DOI: https://doi.org/10.4049/jimmunol.1403249
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    Prostaglandin E2 Inhibits NLRP3 Inflammasome Activation through EP4 Receptor and Intracellular Cyclic AMP in Human Macrophages
    Milena Sokolowska, Li-Yuan Chen, Yueqin Liu, Asuncion Martinez-Anton, Hai-Yan Qi, Carolea Logun, Sara Alsaaty, Yong Hwan Park, Daniel L. Kastner, Jae Jin Chae and James H. Shelhamer
    J Immunol June 1, 2015, 194 (11) 5472-5487; DOI: https://doi.org/10.4049/jimmunol.1401343

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Structural Basis for the Function of Complement Component C4 within the Classical and Lectin Pathways of Complement
    Sofia Mortensen, Rune T. Kidmose, Steen V. Petersen, Ágnes Szilágyi, Zoltan Prohászka and Gregers R. Andersen
    J Immunol June 1, 2015, 194 (11) 5488-5496; DOI: https://doi.org/10.4049/jimmunol.1500087
  • Open Access
    Fc Engineering of Human IgG1 for Altered Binding to the Neonatal Fc Receptor Affects Fc Effector Functions

    Author Choice Article

    Algirdas Grevys, Malin Bern, Stian Foss, Diane Bryant Bratlie, Anders Moen, Kristin Støen Gunnarsen, Audun Aase, Terje Einar Michaelsen, Inger Sandlie and Jan Terje Andersen
    J Immunol June 1, 2015, 194 (11) 5497-5508; DOI: https://doi.org/10.4049/jimmunol.1401218
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    CXCL12 Regulates through JAK1 and JAK2 Formation of Productive Immunological Synapses
    Graciela Cascio, Noa B. Martín-Cófreces, José Miguel Rodríguez-Frade, Pilar López-Cotarelo, Gabriel Criado, José L. Pablos, José Luis Rodríguez-Fernández, Francisco Sánchez-Madrid and Mario Mellado
    J Immunol June 1, 2015, 194 (11) 5509-5519; DOI: https://doi.org/10.4049/jimmunol.1402419

MUCOSAL IMMUNOLOGY

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    Mature Cystic Fibrosis Airway Neutrophils Suppress T Cell Function: Evidence for a Role of Arginase 1 but Not Programmed Death-Ligand 1
    Sarah A. Ingersoll, Julie Laval, Osric A. Forrest, Marcela Preininger, Milton R. Brown, Dalia Arafat, Greg Gibson, Vin Tangpricha and Rabindra Tirouvanziam
    J Immunol June 1, 2015, 194 (11) 5520-5528; DOI: https://doi.org/10.4049/jimmunol.1500312

TUMOR IMMUNOLOGY

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    Pulmonary Alveolar Macrophages Contribute to the Premetastatic Niche by Suppressing Antitumor T Cell Responses in the Lungs
    Sharad K. Sharma, Navin K. Chintala, Surya Kumari Vadrevu, Jalpa Patel, Magdalena Karbowniczek and Maciej M. Markiewski
    J Immunol June 1, 2015, 194 (11) 5529-5538; DOI: https://doi.org/10.4049/jimmunol.1403215
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    Proinflammatory Proteins S100A8/S100A9 Activate NK Cells via Interaction with RAGE
    Kenta Narumi, Reina Miyakawa, Ryosuke Ueda, Hisayoshi Hashimoto, Yuki Yamamoto, Teruhiko Yoshida and Kazunori Aoki
    J Immunol June 1, 2015, 194 (11) 5539-5548; DOI: https://doi.org/10.4049/jimmunol.1402301

NOVEL IMMUNOLOGICAL METHODS

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    A Haptotaxis Assay for Leukocytes Based on Surface-Bound Chemokine Gradients
    Ina Rink, Jan Rink, Dorothea Helmer, Daniel Sachs and Katja Schmitz
    J Immunol June 1, 2015, 194 (11) 5549-5558; DOI: https://doi.org/10.4049/jimmunol.1500148
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    Peripheral Blood–Derived Virus-Specific Memory Stem T Cells Mature to Functional Effector Memory Subsets with Self-Renewal Potency
    Michael Schmueck-Henneresse, Radwa Sharaf, Katrin Vogt, Benjamin J. D. Weist, Sybille Landwehr-Kenzel, Henrike Fuehrer, Anke Jurisch, Nina Babel, Cliona M. Rooney, Petra Reinke and Hans-Dieter Volk
    J Immunol June 1, 2015, 194 (11) 5559-5567; DOI: https://doi.org/10.4049/jimmunol.1402090

CORRECTIONS

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    Correction: Vector-Encoded Helicobacter Pylori Neutrophil-Activating Protein Promotes Maturation of Dendritic Cells with Th1 Polarization and Improved Migration
    Mohanraj Ramachandran, Chuan Jin, Di Yu, Fredrik Eriksson and Magnus Essand
    J Immunol June 1, 2015, 194 (11) 5568; DOI: https://doi.org/10.4049/jimmunol.1500649
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    Correction: The Acute Respiratory Distress Syndrome: From Mechanism to Translation
    SeungHye Han and Rama K. Mallampalli
    J Immunol June 1, 2015, 194 (11) 5569; DOI: https://doi.org/10.4049/jimmunol.1500741
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    Correction: In This Issue
    J Immunol June 1, 2015, 194 (11) 5570; DOI: https://doi.org/10.4049/jimmunol.1500787
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The Journal of Immunology: 194 (11)
The Journal of Immunology
Vol. 194, Issue 11
1 Jun 2015
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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