The Journal of Immunology: 193 (6)

September 15, 2014; Volume 193,Issue 6

IN THIS ISSUE

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In This Issue
A Stable Relationship with IL-17 See article p. 2631
AMIS Analysis See article p. 2902
Global Variation in Innate Immunity See article p. 3003
No Neutrophils Shall Pass See article p. 3023
Neutrophils Aid Mid-Term Pregnancy See article p. 3070
FcRs Fight SIV See articles p. 3113 and 3126

J Immunol September 15, 2014, 193 (6) 2613-2614; DOI: https://doi.org/10.4049/jimmunol.1490032

BRIEF REVIEWS

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Ontogeny and Functions of Central Nervous System Macrophages
Atsuko Katsumoto, Haiyan Lu, Aline S. Miranda and Richard M. Ransohoff

J Immunol September 15, 2014, 193 (6) 2615-2621; DOI: https://doi.org/10.4049/jimmunol.1400716
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Aging of the T Cell Compartment in Mice and Humans: From No Naive Expectations to Foggy Memories
Janko Nikolich-Žugich

J Immunol September 15, 2014, 193 (6) 2622-2629; DOI: https://doi.org/10.4049/jimmunol.1401174

ALLERGY AND OTHER HYPERSENSITIVITIES

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Th17 Cells Demonstrate Stable Cytokine Production in a Proallergic Environment
Nicole L. Glosson-Byers, Sarita Sehra, Gretta L. Stritesky, Qing Yu, Olufolakemi Awe, Duy Pham, Heather A. Bruns and Mark H. Kaplan

J Immunol September 15, 2014, 193 (6) 2631-2640; DOI: https://doi.org/10.4049/jimmunol.1401202

ANTIGEN RECOGNITION AND RESPONSES

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The MHC Class II Cofactor HLA-DM Interacts with Ig in B Cells
Henriette Macmillan, Michael J. Strohman, Sashi Ayyangar, Wei Jiang, Narendiran Rajasekaran, Armin Spura, Ann J. Hessell, Anne-Marie Madec and Elizabeth D. Mellins

J Immunol September 15, 2014, 193 (6) 2641-2650; DOI: https://doi.org/10.4049/jimmunol.1400075
Open Access
Selective Phosphorylation of the Dlg1AB Variant Is Critical for TCR-Induced p38 Activation and Induction of Proinflammatory Cytokines in CD8⁺ T Cells
Author Choice Article

Jillian Crocetti, Oscar Silva, Lisa A. Humphries, Michelle D. Tibbs and M. Carrie Miceli

J Immunol September 15, 2014, 193 (6) 2651-2660; DOI: https://doi.org/10.4049/jimmunol.1401196

AUTOIMMUNITY

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The Fli-1 Transcription Factor Regulates the Expression of CCL5/RANTES
Mara L. Lennard Richard, Shuzo Sato, Eiji Suzuki, Sarah Williams, Tamara K. Nowling and Xian K. Zhang

J Immunol September 15, 2014, 193 (6) 2661-2668; DOI: https://doi.org/10.4049/jimmunol.1302779
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CD1d^hiCD5⁺ B Cells Expanded by GM-CSF In Vivo Suppress Experimental Autoimmune Myasthenia Gravis
Jian Rong Sheng, Songhua Quan and Betty Soliven

J Immunol September 15, 2014, 193 (6) 2669-2677; DOI: https://doi.org/10.4049/jimmunol.1303397
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Thymic Epithelium Determines a Spontaneous Chronic Neuritis in Icam1^tm1JcgrNOD Mice
Gerd Meyer zu Horste, Anne K. Mausberg, Steffen Cordes, Houda El-Haddad, Hans-Joachim Partke, Verena I. Leussink, Michael Roden, Stephan Martin, Lawrence Steinman, Hans-Peter Hartung and Bernd C. Kieseier

J Immunol September 15, 2014, 193 (6) 2678-2690; DOI: https://doi.org/10.4049/jimmunol.1400367
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Idiotype-Specific Th Cells Support Oligoclonal Expansion of Anti-dsDNA B Cells in Mice with Lupus
Kristin Aas-Hanssen, Ane Funderud, Keith M. Thompson, Bjarne Bogen and Ludvig A. Munthe

J Immunol September 15, 2014, 193 (6) 2691-2698; DOI: https://doi.org/10.4049/jimmunol.1400640

CLINICAL AND HUMAN IMMUNOLOGY

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Hypomethylation at the Regulatory T Cell–Specific Demethylated Region in CD25^hi T Cells Is Decoupled from FOXP3 Expression at the Inflamed Site in Childhood Arthritis
Author Choice Article

David Bending, Anne M. Pesenacker, Simona Ursu, Qiong Wu, Hannah Lom, Balathas Thirugnanabalan and Lucy R. Wedderburn

J Immunol September 15, 2014, 193 (6) 2699-2708; DOI: https://doi.org/10.4049/jimmunol.1400599

IMMUNE REGULATION

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Helminth-Conditioned Dendritic Cells Prime CD4⁺ T Cells to IL-4 Production In Vivo
Lisa M. Connor, Shiau-Choot Tang, Mali Camberis, Graham Le Gros and Franca Ronchese

J Immunol September 15, 2014, 193 (6) 2709-2717; DOI: https://doi.org/10.4049/jimmunol.1400374
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The Late Endosomal Transporter CD222 Directs the Spatial Distribution and Activity of Lck
Karin Pfisterer, Florian Forster, Wolfgang Paster, Verena Supper, Anna Ohradanova-Repic, Paul Eckerstorfer, Alexander Zwirzitz, Clemens Donner, Cyril Boulegue, Herbert B. Schiller, Gabriela Ondrovičová, Oreste Acuto, Hannes Stockinger and Vladimir Leksa

J Immunol September 15, 2014, 193 (6) 2718-2732; DOI: https://doi.org/10.4049/jimmunol.1303349
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IFNαR Signaling in Effector but Not Regulatory T Cells Is Required for Immune Dysregulation during Type I IFN–Dependent Inflammatory Disease
Shivani Srivastava, Lisa K. Koch and Daniel J. Campbell

J Immunol September 15, 2014, 193 (6) 2733-2742; DOI: https://doi.org/10.4049/jimmunol.1401039
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Hepatocyte Growth Factor Limits Autoimmune Neuroinflammation via Glucocorticoid-Induced Leucine Zipper Expression in Dendritic Cells
Mahdia Benkhoucha, Nicolas Molnarfi, Isabelle Dunand-Sauthier, Doron Merkler, Gregory Schneiter, Stefano Bruscoli, Carlo Riccardi, Yasuhiko Tabata, Hiroshi Funakoshi, Toshikazu Nakamura, Walter Reith, Marie-Laure Santiago-Raber and Patrice H. Lalive

J Immunol September 15, 2014, 193 (6) 2743-2752; DOI: https://doi.org/10.4049/jimmunol.1302338
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The Role of Metalloproteinase ADAM17 in Regulating ICOS Ligand–Mediated Humoral Immune Responses
Joanna Marczynska, Aleksandra Ozga, Agnieszka Wlodarczyk, Monika Majchrzak-Gorecka, Paulina Kulig, Magdalena Banas, Dominika Michalczyk-Wetula, Pawel Majewski, Andreas Hutloff, Jeanette Schwarz, Athena Chalaris, Jürgen Scheller, Stefan Rose-John and Joanna Cichy

J Immunol September 15, 2014, 193 (6) 2753-2763; DOI: https://doi.org/10.4049/jimmunol.1302893
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A Truncated Human NKG2D Splice Isoform Negatively Regulates NKG2D-Mediated Function
Mobin A. Karimi, Oscar A. Aguilar, Baixiang Zou, Michael H. Bachmann, James R. Carlyle, Cynthia L. Baldwin and Taku Kambayashi

J Immunol September 15, 2014, 193 (6) 2764-2771; DOI: https://doi.org/10.4049/jimmunol.1400920
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6-Methoxyflavone Inhibits NFAT Translocation into the Nucleus and Suppresses T Cell Activation
Jae-Seon So, Gi-Cheon Kim, Minkyung Song, Choong-Gu Lee, Eunbee Park, Ho Jin Kim, Young Sup Kim, Chang-Duk Jun and Sin-Hyeog Im

J Immunol September 15, 2014, 193 (6) 2772-2783; DOI: https://doi.org/10.4049/jimmunol.1400285
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Differences in the Transduction of Canonical Wnt Signals Demarcate Effector and Memory CD8 T Cells with Distinct Recall Proliferation Capacity
Caroline Boudousquié, Maxime Danilo, Laurène Pousse, Beena Jeevan-Raj, Georgi S. Angelov, Vijaykumar Chennupati, Dietmar Zehn and Werner Held

J Immunol September 15, 2014, 193 (6) 2784-2791; DOI: https://doi.org/10.4049/jimmunol.1400465
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Dopamine Inhibits the Effector Functions of Activated NK Cells via the Upregulation of the D5 Receptor
Joanna Mikulak, Luisa Bozzo, Alessandra Roberto, Elena Pontarini, Paolo Tentorio, Kelly Hudspeth, Enrico Lugli and Domenico Mavilio

J Immunol September 15, 2014, 193 (6) 2792-2800; DOI: https://doi.org/10.4049/jimmunol.1401114
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Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis
Bo Tao, Wei Jin, Jiaqi Xu, Zuyu Liang, Junlin Yao, Yun Zhang, Kai Wang, Hongqiang Cheng, Xue Zhang and Yuehai Ke

J Immunol September 15, 2014, 193 (6) 2801-2811; DOI: https://doi.org/10.4049/jimmunol.1303463
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Antigen Signal Strength during Priming Determines Effector CD4 T Cell Function and Antigen Sensitivity during Influenza Virus Challenge
Mika Nagaoka, Yasuko Hatta, Yoshihiro Kawaoka and Laurent P. Malherbe

J Immunol September 15, 2014, 193 (6) 2812-2820; DOI: https://doi.org/10.4049/jimmunol.1401358
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Mechanistic Target of Rapamycin Inhibition Extends Cellular Lifespan in Dendritic Cells by Preserving Mitochondrial Function
Eyal Amiel, Bart Everts, Daniel Fritz, Saritha Beauchamp, Burong Ge, Erika L. Pearce and Edward J. Pearce

J Immunol September 15, 2014, 193 (6) 2821-2830; DOI: https://doi.org/10.4049/jimmunol.1302498
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Innate Immune Cell CD45 Regulates Lymphopenia-Induced T Cell Proliferation
Amy E. Saunders, Yaein A. Shim and Pauline Johnson

J Immunol September 15, 2014, 193 (6) 2831-2842; DOI: https://doi.org/10.4049/jimmunol.1302681
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Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β₈
Justin P. Edwards, Angela M. Thornton and Ethan M. Shevach

J Immunol September 15, 2014, 193 (6) 2843-2849; DOI: https://doi.org/10.4049/jimmunol.1401102
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A Novel Role for Histone Deacetylase 6 in the Regulation of the Tolerogenic STAT3/IL-10 Pathway in APCs
Fengdong Cheng, Maritza Lienlaf, Hong-Wei Wang, Patricio Perez-Villarroel, Calvin Lee, Karrune Woan, Jennifer Rock-Klotz, Eva Sahakian, David Woods, Javier Pinilla-Ibarz, Jay Kalin, Jianguo Tao, Wayne Hancock, Alan Kozikowski, Edward Seto, Alejandro Villagra and Eduardo M. Sotomayor

J Immunol September 15, 2014, 193 (6) 2850-2862; DOI: https://doi.org/10.4049/jimmunol.1302778

IMMUNE SYSTEM DEVELOPMENT

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CD11a Is Essential for Normal Development of Hematopoietic Intermediates
Tina O. Bose, Sara L. Colpitts, Quynh-Mai Pham, Lynn Puddington and Leo Lefrançois

J Immunol September 15, 2014, 193 (6) 2863-2872; DOI: https://doi.org/10.4049/jimmunol.1301820
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Zap70 Is Essential for Long-Term Survival of Naive CD8 T Cells
Ina Schim van der Loeff, Lih-Yun Hsu, Manoj Saini, Art Weiss and Benedict Seddon

J Immunol September 15, 2014, 193 (6) 2873-2880; DOI: https://doi.org/10.4049/jimmunol.1400858
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The Ataxia Telangiectasia Mutated and Cyclin D3 Proteins Cooperate To Help Enforce TCRβ and IgH Allelic Exclusion
Natalie C. Steinel, Megan R. Fisher, Katherine S. Yang-Iott and Craig H. Bassing

J Immunol September 15, 2014, 193 (6) 2881-2890; DOI: https://doi.org/10.4049/jimmunol.1302201

IMMUNOGENETICS

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The Proto-MHC of Placozoans, a Region Specialized in Cellular Stress and Ubiquitination/Proteasome Pathways
Jaanus Suurväli, Luc Jouneau, Dominique Thépot, Simona Grusea, Pierre Pontarotti, Louis Du Pasquier, Sirje Rüütel Boudinot and Pierre Boudinot

J Immunol September 15, 2014, 193 (6) 2891-2901; DOI: https://doi.org/10.4049/jimmunol.1401177

IMMUNOTHERAPY AND VACCINES

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Antibody-Mediated Immune Suppression of Erythrocyte Alloimmunization Can Occur Independently from Red Cell Clearance or Epitope Masking in a Murine Model
Honghui Yu, Sean R. Stowell, Lidice Bernardo, Jeanne E. Hendrickson, James C. Zimring, Alaa Amash, Makoto Uchikawa and Alan H. Lazarus

J Immunol September 15, 2014, 193 (6) 2902-2910; DOI: https://doi.org/10.4049/jimmunol.1302287
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Immune Subdominant Antigens as Vaccine Candidates against Mycobacterium tuberculosis
Mark T. Orr, Gregory C. Ireton, Elyse A. Beebe, Po-Wei D. Huang, Valerie A. Reese, David Argilla, Rhea N. Coler and Steven G. Reed

J Immunol September 15, 2014, 193 (6) 2911-2918; DOI: https://doi.org/10.4049/jimmunol.1401103

INFECTIOUS DISEASE AND HOST RESPONSE

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Systemic Inflammatory Response Elicited by Superantigen Destabilizes T Regulatory Cells, Rendering Them Ineffective during Toxic Shock Syndrome
Ashenafi Y. Tilahun, Vaidehi R. Chowdhary, Chella S. David and Govindarajan Rajagopalan

J Immunol September 15, 2014, 193 (6) 2919-2930; DOI: https://doi.org/10.4049/jimmunol.1400980
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Transcriptional Profile of Tuberculosis Antigen–Specific T Cells Reveals Novel Multifunctional Features
Cecilia Lindestam Arlehamn, Gregory Seumois, Anna Gerasimova, Charlie Huang, Zheng Fu, Xiaojing Yue, Alessandro Sette, Pandurangan Vijayanand and Bjoern Peters

J Immunol September 15, 2014, 193 (6) 2931-2940; DOI: https://doi.org/10.4049/jimmunol.1401151
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Chlamydia trachomatis Inhibits Inducible NO Synthase in Human Mesenchymal Stem Cells by Stimulating Polyamine Synthesis
Mohammad Abu-Lubad, Thomas F. Meyer and Munir A. Al-Zeer

J Immunol September 15, 2014, 193 (6) 2941-2951; DOI: https://doi.org/10.4049/jimmunol.1400377
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Activated CD8⁺ T Cells Induce Expansion of Vβ5⁺ Regulatory T Cells via TNFR2 Signaling
Jara J. Joedicke, Lara Myers, Aaron B. Carmody, Ronald J. Messer, Harald Wajant, Karl S. Lang, Philipp A. Lang, Tak W. Mak, Kim J. Hasenkrug and Ulf Dittmer

J Immunol September 15, 2014, 193 (6) 2952-2960; DOI: https://doi.org/10.4049/jimmunol.1400649
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The Immunotherapeutic Role of Regulatory T Cells in Leishmania (Viannia) panamensis Infection
Allison Ehrlich, Tiago Moreno Castilho, Karen Goldsmith-Pestana, Wook-Jin Chae, Alfred L. M. Bothwell, Tim Sparwasser and Diane McMahon-Pratt

J Immunol September 15, 2014, 193 (6) 2961-2970; DOI: https://doi.org/10.4049/jimmunol.1400728
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Pregnancy and Malaria Exposure Are Associated with Changes in the B Cell Pool and in Plasma Eotaxin Levels
Pilar Requena, Joseph J. Campo, Alexandra J. Umbers, Maria Ome, Regina Wangnapi, Diana Barrios, Leanne J. Robinson, Paula Samol, Anna Rosanas-Urgell, Itziar Ubillos, Alfredo Mayor, Marta López, Elisa de Lazzari, Myriam Arévalo-Herrera, Carmen Fernández-Becerra, Hernando del Portillo, Chetan E. Chitnis, Peter M. Siba, Azucena Bardají, Ivo Mueller, Stephen Rogerson, Clara Menéndez and Carlota Dobaño

J Immunol September 15, 2014, 193 (6) 2971-2983; DOI: https://doi.org/10.4049/jimmunol.1401037
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MyD88 Signaling Inhibits Protective Immunity to the Gastrointestinal Helminth Parasite Heligmosomoides polygyrus
Author Choice Article

Lisa A. Reynolds, Yvonne Harcus, Katherine A. Smith, Lauren M. Webb, James P. Hewitson, Ewan A. Ross, Sheila Brown, Satoshi Uematsu, Shizuo Akira, David Gray, Mohini Gray, Andrew S. MacDonald, Adam F. Cunningham and Rick M. Maizels

J Immunol September 15, 2014, 193 (6) 2984-2993; DOI: https://doi.org/10.4049/jimmunol.1401056

INNATE IMMUNITY AND INFLAMMATION

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The Natural Product Phyllanthusmin C Enhances IFN-γ Production by Human NK Cells through Upregulation of TLR-Mediated NF-κB Signaling
Youcai Deng, Jianhong Chu, Yulin Ren, Zhijin Fan, Xiaotian Ji, Bethany Mundy-Bosse, Shunzong Yuan, Tiffany Hughes, Jianying Zhang, Baljash Cheema, Andrew T. Camardo, Yong Xia, Lai-Chu Wu, Li-Shu Wang, Xiaoming He, A. Douglas Kinghorn, Xiaohui Li, Michael A Caligiuri and Jianhua Yu

J Immunol September 15, 2014, 193 (6) 2994-3002; DOI: https://doi.org/10.4049/jimmunol.1302600
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Single-Cell Analysis of Innate Cytokine Responses to Pattern Recognition Receptor Stimulation in Children across Four Continents
Kinga K. Smolen, Bing Cai, Laura Gelinas, Edgardo S. Fortuno III, Martin Larsen, David P. Speert, Mustapha Chamekh, Philip J. Cooper, Monika Esser, Arnaud Marchant and Tobias R. Kollmann

J Immunol September 15, 2014, 193 (6) 3003-3012; DOI: https://doi.org/10.4049/jimmunol.1400895
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Heme Oxygenase-1 Dysregulates Macrophage Polarization and the Immune Response to Helicobacter pylori
Alain P. Gobert, Thomas Verriere, Mohammad Asim, Daniel P. Barry, M. Blanca Piazuelo, Thibaut de Sablet, Alberto G. Delgado, Luis E. Bravo, Pelayo Correa, Richard M. Peek Jr., Rupesh Chaturvedi and Keith T. Wilson

J Immunol September 15, 2014, 193 (6) 3013-3022; DOI: https://doi.org/10.4049/jimmunol.1401075
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Prevention of Neutrophil Extravasation by α2-Adrenoceptor–Mediated Endothelial Stabilization
Ada María Herrera-García, María Jesús Domínguez-Luis, María Arce-Franco, Estefanía Armas-González, Diego Álvarez de La Rosa, José David Machado, Martina K. Pec, Manuel Feria, Olga Barreiro, Francisco Sánchez-Madrid and Federico Díaz-González

J Immunol September 15, 2014, 193 (6) 3023-3035; DOI: https://doi.org/10.4049/jimmunol.1400255
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IFN-γ Primes Macrophage Activation by Increasing Phosphatase and Tensin Homolog via Downregulation of miR-3473b
Cong Wu, Yiquan Xue, Pin Wang, Li Lin, Qiuyan Liu, Nan Li, Junfang Xu and Xuetao Cao

J Immunol September 15, 2014, 193 (6) 3036-3044; DOI: https://doi.org/10.4049/jimmunol.1302379
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Concomitant TLR/RLH Signaling of Radioresistant and Radiosensitive Cells Is Essential for Protection against Vesicular Stomatitis Virus Infection
Julia Spanier, Stefan Lienenklaus, Jennifer Paijo, Annett Kessler, Katharina Borst, Sabrina Heindorf, Darren P. Baker, Andrea Kröger, Siegfried Weiss, Claudia N. Detje, Peter Staeheli and Ulrich Kalinke

J Immunol September 15, 2014, 193 (6) 3045-3054; DOI: https://doi.org/10.4049/jimmunol.1400959
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Peptidoglycan Recognition Protein 3 and Nod2 Synergistically Protect Mice from Dextran Sodium Sulfate–Induced Colitis
Xuefang Jing, Fareeha Zulfiqar, Shin Yong Park, Gabriel Núñez, Roman Dziarski and Dipika Gupta

J Immunol September 15, 2014, 193 (6) 3055-3069; DOI: https://doi.org/10.4049/jimmunol.1301548
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Identification of a Novel Neutrophil Population: Proangiogenic Granulocytes in Second-Trimester Human Decidua
Hagai Amsalem, Melissa Kwan, Aleah Hazan, Jianhong Zhang, Rebecca L. Jones, Wendy Whittle, John C. P. Kingdom, B. Anne Croy, Stephen J. Lye and Caroline E. Dunk

J Immunol September 15, 2014, 193 (6) 3070-3079; DOI: https://doi.org/10.4049/jimmunol.1303117
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SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome
Chong-Shan Shi, Hai-Yan Qi, Cedric Boularan, Ning-Na Huang, Mones Abu-Asab, James H. Shelhamer and John H. Kehrl

J Immunol September 15, 2014, 193 (6) 3080-3089; DOI: https://doi.org/10.4049/jimmunol.1303196

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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The N-Terminal Domain of NLRC5 Confers Transcriptional Activity for MHC Class I and II Gene Expression
Andreas Neerincx, Kristin Jakobshagen, Olaf Utermöhlen, Hildegard Büning, Viktor Steimle and Thomas A. Kufer

J Immunol September 15, 2014, 193 (6) 3090-3100; DOI: https://doi.org/10.4049/jimmunol.1401065
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Trafficking of LAG-3 to the Surface on Activated T Cells via Its Cytoplasmic Domain and Protein Kinase C Signaling
Joonbeom Bae, Suk Jun Lee, Chung-Gyu Park, Young Sik Lee and Taehoon Chun

J Immunol September 15, 2014, 193 (6) 3101-3112; DOI: https://doi.org/10.4049/jimmunol.1401025

MUCOSAL IMMUNOLOGY

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Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Local Antibody Production and Concentration on the Path of Virus Entry
Qingsheng Li, Ming Zeng, Lijie Duan, James E. Voss, Anthony J. Smith, Stefan Pambuccian, Liang Shang, Stephen Wietgrefe, Peter J. Southern, Cavan S. Reilly, Pamela J. Skinner, Mary L. Zupancic, John V. Carlis, Michael Piatak Jr., Diane Waterman, R. Keith Reeves, Katherine Masek-Hammerman, Cynthia A. Derdeyn, Michael D. Alpert, David T. Evans, Heinz Kohler, Sybille Müller, James Robinson, Jeffrey D. Lifson, Dennis R. Burton, R. Paul Johnson and Ashley T. Haase

J Immunol September 15, 2014, 193 (6) 3113-3125; DOI: https://doi.org/10.4049/jimmunol.1400820
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Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Immune Complex–Inhibitory Fc Receptor Interactions That Reduce Target Cell Availability
Anthony J. Smith, Stephen W. Wietgrefe, Liang Shang, Cavan S. Reilly, Peter J. Southern, Katherine E. Perkey, Lijie Duan, Heinz Kohler, Sybille Müller, James Robinson, John V. Carlis, Qingsheng Li, R. Paul Johnson and Ashley T. Haase

J Immunol September 15, 2014, 193 (6) 3126-3133; DOI: https://doi.org/10.4049/jimmunol.1400822
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Cigarette Smoke Primes the Pulmonary Environment to IL-1α/CXCR-2–Dependent Nontypeable Haemophilus influenzae–Exacerbated Neutrophilia in Mice
Jake K. Nikota, Pamela Shen, Mathieu C. Morissette, Kimberly Fernandes, Abraham Roos, Derek K. Chu, Nicole G. Barra, Yoichiro Iwakura, Roland Kolbeck, Alison A. Humbles and Martin R. Stampfli

J Immunol September 15, 2014, 193 (6) 3134-3145; DOI: https://doi.org/10.4049/jimmunol.1302412

TUMOR IMMUNOLOGY

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Secretion and Immunogenicity of the Meningioma-Associated Antigen TXNDC16
Christian Harz, Nicole Ludwig, Sven Lang, Tamara V. Werner, Valentina Galata, Christina Backes, Katja Schmitt, Ruth Nickels, Elmar Krause, Martin Jung, Jens Rettig, Andreas Keller, Michael Menger, Richard Zimmermann and Eckart Meese

J Immunol September 15, 2014, 193 (6) 3146-3154; DOI: https://doi.org/10.4049/jimmunol.1303098
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Role of TGF-β Signaling in Generation of CD39⁺CD73⁺ Myeloid Cells in Tumors
Sergey V. Ryzhov, Michael W. Pickup, Anna Chytil, Agnieszka E. Gorska, Qinkun Zhang, Philip Owens, Igor Feoktistov, Harold L. Moses and Sergey V. Novitskiy

J Immunol September 15, 2014, 193 (6) 3155-3164; DOI: https://doi.org/10.4049/jimmunol.1400578
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The Expression of Sphingosine-1 Phosphate Receptor-1 in Chronic Lymphocytic Leukemia Cells Is Impaired by Tumor Microenvironmental Signals and Enhanced by Piceatannol and R406
Mercedes Borge, Federico Remes Lenicov, Paula R. Nannini, María M. de los Ríos Alicandú, Enrique Podaza, Ana Ceballos, Horacio Fernández Grecco, María Cabrejo, Raimundo F. Bezares, Pablo E. Morande, Pablo Oppezzo, Mirta Giordano and Romina Gamberale

J Immunol September 15, 2014, 193 (6) 3165-3174; DOI: https://doi.org/10.4049/jimmunol.1400547

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Table of Contents

IN THIS ISSUE

BRIEF REVIEWS

ALLERGY AND OTHER HYPERSENSITIVITIES

ANTIGEN RECOGNITION AND RESPONSES

AUTOIMMUNITY

CLINICAL AND HUMAN IMMUNOLOGY

IMMUNE REGULATION

IMMUNE SYSTEM DEVELOPMENT

IMMUNOGENETICS

IMMUNOTHERAPY AND VACCINES

INFECTIOUS DISEASE AND HOST RESPONSE

INNATE IMMUNITY AND INFLAMMATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

MUCOSAL IMMUNOLOGY

TUMOR IMMUNOLOGY

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