On the cover: Confocal micrograph showing IL-1R type 1 immunostaining (red) in the spinal cord of a naive C57BL/6 mouse, in close proximity with blood vessel basement membranes (pan-laminin immunostaining, green). Firm adhesion of neutrophils to the inflamed spinal microvasculature is regulated by IL-1R type 1 during experimental autoimmune encephalomyelitis. Aubé, B., S. A. Lévesque, A. Paré, É. Chamma, H. Kébir, R. Gorina, M.-A. Lécuyer, J. I. Alvarez, Y. De Koninck, B. Engelhardt, A. Prat, D. Côté, and S. Lacroix. 2014. Neutrophils mediate blood–spinal cord barrier disruption in demyelinating neuroinflammatory diseases. J. Immunol. 193: 2438–2454.