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The Journal of Immunology

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Table of Contents

August 15, 2014; Volume 193,Issue 4

IN THIS ISSUE

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    In This Issue

    IL-17 Signaling in Two ACTs See articles p. 1590

    Deriving Distinct DCs See article p. 1622

    Prioritizing Proteomic Profiling See article p. 1812

    Platelets Modulate Monocytes in Dengue Disease See article p. 1864

    A Superantigen Wedge between TCR and MHC See article p. 1998

    J Immunol August 15, 2014, 193 (4) 1517-1518; DOI: https://doi.org/10.4049/jimmunol.1490028

TRANSLATING IMMUNOLOGY

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    Translational Medicine in Action: Anti-CD20 Therapy in Lymphoma
    Sean H. Lim and Ronald Levy
    J Immunol August 15, 2014, 193 (4) 1519-1524; DOI: https://doi.org/10.4049/jimmunol.1490027

BRIEF REVIEWS

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    Too Much of a Good Thing? Tim-3 and TCR Signaling in T Cell Exhaustion
    Robert L. Ferris, Binfeng Lu and Lawrence P. Kane
    J Immunol August 15, 2014, 193 (4) 1525-1530; DOI: https://doi.org/10.4049/jimmunol.1400557
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    Dendritic Cells and B Cells: Unexpected Partners in Th2 Development
    Beatriz León, André Ballesteros-Tato and Frances E. Lund
    J Immunol August 15, 2014, 193 (4) 1531-1537; DOI: https://doi.org/10.4049/jimmunol.1400149

CUTTING EDGE

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    Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo
    Apostolos Polykratis, Nicole Hermance, Matija Zelic, Justine Roderick, Chun Kim, Trieu-My Van, Thomas H. Lee, Francis K. M. Chan, Manolis Pasparakis and Michelle A. Kelliher
    J Immunol August 15, 2014, 193 (4) 1539-1543; DOI: https://doi.org/10.4049/jimmunol.1400590
  • Open Access
    Cutting Edge: An Antibody Recognizing Ancestral Endogenous Virus Glycoproteins Mediates Antibody-Dependent Cellular Cytotoxicity on HIV-1–Infected Cells

    Author Choice Article

    Henri-Alexandre Michaud, Devi SenGupta, Miguel de Mulder, Steven G. Deeks, Jeffrey N. Martin, James J. Kobie, Jonah B. Sacha and Douglas F. Nixon
    J Immunol August 15, 2014, 193 (4) 1544-1548; DOI: https://doi.org/10.4049/jimmunol.1302108

ALLERGY AND OTHER HYPERSENSITIVITIES

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    IL-33 and Thymic Stromal Lymphopoietin Mediate Immune Pathology in Response to Chronic Airborne Allergen Exposure
    Koji Iijima, Takao Kobayashi, Kenichiro Hara, Gail M. Kephart, Steven F. Ziegler, Andrew N. McKenzie and Hirohito Kita
    J Immunol August 15, 2014, 193 (4) 1549-1559; DOI: https://doi.org/10.4049/jimmunol.1302984

ANTIGEN RECOGNITION AND RESPONSES

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    Targeted Delivery of Mycobacterial Antigens to Human Dendritic Cells via Siglec-7 Induces Robust T Cell Activation
    Norihito Kawasaki, Cory D. Rillahan, Tan-Yun Cheng, Ildiko Van Rhijn, Matthew S. Macauley, D. Branch Moody and James C. Paulson
    J Immunol August 15, 2014, 193 (4) 1560-1566; DOI: https://doi.org/10.4049/jimmunol.1303278
  • Open Access
    Clonotypic Composition of the CD4+ T Cell Response to a Vectored Retroviral Antigen Is Determined by Its Speed

    Author Choice Article

    Georgina Thorborn, Mickaël J. Ploquin, Urszula Eksmond, Rebecca Pike, Wibke Bayer, Ulf Dittmer, Kim J. Hasenkrug, Marion Pepper and George Kassiotis
    J Immunol August 15, 2014, 193 (4) 1567-1577; DOI: https://doi.org/10.4049/jimmunol.1400667
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    Cowpox Virus Protein CPXV012 Eludes CTLs by Blocking ATP Binding to TAP
    Rutger D. Luteijn, Hanneke Hoelen, Elisabeth Kruse, Wouter F. van Leeuwen, Jennine Grootens, Daniëlle Horst, Martijn Koorengevel, Jan W. Drijfhout, Elisabeth Kremmer, Klaus Früh, Jacques J. Neefjes, Antoinette Killian, Robert Jan Lebbink, Maaike E. Ressing and Emmanuel J. H. J. Wiertz
    J Immunol August 15, 2014, 193 (4) 1578-1589; DOI: https://doi.org/10.4049/jimmunol.1400964

AUTOIMMUNITY

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    The Differential Regulation of Human ACT1 Isoforms by Hsp90 in IL-17 Signaling
    Ling Wu, Chenhui Wang, Bertrand Boisson, Saurav Misra, Patricia Rayman, James H. Finke, Anne Puel, Jean-Laurent Casanova and Xiaoxia Li
    J Immunol August 15, 2014, 193 (4) 1590-1599; DOI: https://doi.org/10.4049/jimmunol.1400715
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    Recombinant Human IgA1 and IgA2 Autoantibodies to Type VII Collagen Induce Subepidermal Blistering Ex Vivo
    Andreas Recke, Luisa M. Trog, Hendri H. Pas, Artem Vorobyev, Aida Abadpour, Marcel F. Jonkman, Ger van Zandbergen, Claudia Kauderer, Detlef Zillikens, Gestur Vidarsson and Ralf J. Ludwig
    J Immunol August 15, 2014, 193 (4) 1600-1608; DOI: https://doi.org/10.4049/jimmunol.1400160
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    Activation of Rheumatoid Factor–Specific B Cells Is Antigen Dependent and Occurs Preferentially Outside of Germinal Centers in the Lupus-Prone NZM2410 Mouse Model
    Allison Sang, Haitao Niu, Jaime Cullen, Seung Chul Choi, Ying Yi Zheng, Haowei Wang, Mark J. Shlomchik and Laurence Morel
    J Immunol August 15, 2014, 193 (4) 1609-1621; DOI: https://doi.org/10.4049/jimmunol.1303000

CLINICAL AND HUMAN IMMUNOLOGY

  • Open Access
    Human XCR1+ Dendritic Cells Derived In Vitro from CD34+ Progenitors Closely Resemble Blood Dendritic Cells, Including Their Adjuvant Responsiveness, Contrary to Monocyte-Derived Dendritic Cells

    Author Choice Article

    Sreekumar Balan, Vincent Ollion, Nicholas Colletti, Rabie Chelbi, Frédéric Montanana-Sanchis, Hong Liu, Thien-Phong Vu Manh, Cindy Sanchez, Juliette Savoret, Ivan Perrot, Anne-Claire Doffin, Even Fossum, Didier Bechlian, Christian Chabannon, Bjarne Bogen, Carine Asselin-Paturel, Michael Shaw, Timothy Soos, Christophe Caux, Jenny Valladeau-Guilemond and Marc Dalod
    J Immunol August 15, 2014, 193 (4) 1622-1635; DOI: https://doi.org/10.4049/jimmunol.1401243

IMMUNE REGULATION

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    Lymph Node Stromal Cells Negatively Regulate Antigen-Specific CD4+ T Cell Responses
    Jun Abe, Shigeyuki Shichino, Satoshi Ueha, Shin-ichi Hashimoto, Michio Tomura, Yutaka Inagaki, Jens V. Stein and Kouji Matsushima
    J Immunol August 15, 2014, 193 (4) 1636-1644; DOI: https://doi.org/10.4049/jimmunol.1302946
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    γδT Cells Drive Myeloid-Derived Suppressor Cell–Mediated CD8+ T Cell Exhaustion in Hepatitis B Virus–Induced Immunotolerance
    Xiaohui Kong, Rui Sun, Yongyan Chen, Haiming Wei and Zhigang Tian
    J Immunol August 15, 2014, 193 (4) 1645-1653; DOI: https://doi.org/10.4049/jimmunol.1303432
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    The NKG2D Ligand ULBP2 Is Specifically Regulated through an Invariant Chain–Dependent Endosomal Pathway
    Franziska Uhlenbrock, Michael Hagemann-Jensen, Stephanie Kehlet, Lars Andresen, Silvia Pastorekova and Søren Skov
    J Immunol August 15, 2014, 193 (4) 1654-1665; DOI: https://doi.org/10.4049/jimmunol.1303275
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    Regulation of Intestinal IgA Responses by Dietary Palmitic Acid and Its Metabolism
    Jun Kunisawa, Eri Hashimoto, Asuka Inoue, Risa Nagasawa, Yuji Suzuki, Izumi Ishikawa, Shiori Shikata, Makoto Arita, Junken Aoki and Hiroshi Kiyono
    J Immunol August 15, 2014, 193 (4) 1666-1671; DOI: https://doi.org/10.4049/jimmunol.1302944
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    Deltex1 Promotes Protein Kinase Cθ Degradation and Sustains Casitas B-Lineage Lymphoma Expression
    Tzu-Sheng Hsu, Huey-Wen Hsiao, Pei-Jung Wu, Wen-Hsien Liu and Ming-Zong Lai
    J Immunol August 15, 2014, 193 (4) 1672-1680; DOI: https://doi.org/10.4049/jimmunol.1301416
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    Marginal Zone B Cells Transport IgG3-Immune Complexes to Splenic Follicles
    Lu Zhang, Zhoujie Ding, Hui Xu and Birgitta Heyman
    J Immunol August 15, 2014, 193 (4) 1681-1689; DOI: https://doi.org/10.4049/jimmunol.1400331
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    Repression of Arginase-2 Expression in Dendritic Cells by MicroRNA-155 Is Critical for Promoting T Cell Proliferation
    Isabelle Dunand-Sauthier, Magali Irla, Stéphanie Carnesecchi, Queralt Seguín-Estévez, Charles E. Vejnar, Evgeny M. Zdobnov, Marie-Laure Santiago-Raber and Walter Reith
    J Immunol August 15, 2014, 193 (4) 1690-1700; DOI: https://doi.org/10.4049/jimmunol.1301913
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    Distinct Fcγ Receptors Mediate the Effect of Serum Amyloid P on Neutrophil Adhesion and Fibrocyte Differentiation
    Nehemiah Cox, Darrell Pilling and Richard H. Gomer
    J Immunol August 15, 2014, 193 (4) 1701-1708; DOI: https://doi.org/10.4049/jimmunol.1400281
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    Increased Antitumor Effects Using IL-2 with Anti–TGF-β Reveals Competition between Mouse NK and CD8 T Cells
    Maite Alvarez, Myriam N. Bouchlaka, Gail D. Sckisel, Can M. Sungur, Mingyi Chen and William J. Murphy
    J Immunol August 15, 2014, 193 (4) 1709-1716; DOI: https://doi.org/10.4049/jimmunol.1400034
  • Open Access
    Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses

    Author Choice Article

    Emine Sahin, Stefan Haubenwallner, Mario Kuttke, Isabella Kollmann, Angela Halfmann, Alexander B. Dohnal, Li Chen, Paul Cheng, Bastian Hoesel, Elisa Einwallner, Julia Brunner, Julia B. Kral, Waltraud C. Schrottmaier, Kathrin Thell, Victoria Saferding, Stephan Blüml and Gernot Schabbauer
    J Immunol August 15, 2014, 193 (4) 1717-1727; DOI: https://doi.org/10.4049/jimmunol.1302167
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    Lnk/Sh2b3 Controls the Production and Function of Dendritic Cells and Regulates the Induction of IFN-γ–Producing T Cells
    Taizo Mori, Yukiko Iwasaki, Yoichi Seki, Masanori Iseki, Hiroko Katayama, Kazuhiko Yamamoto, Kiyoshi Takatsu and Satoshi Takaki
    J Immunol August 15, 2014, 193 (4) 1728-1736; DOI: https://doi.org/10.4049/jimmunol.1303243
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    Leukocyte β7 Integrin Targeted by Krüppel-like Factors
    Melanie Alles, Gleb Turchinovich, Pumin Zhang, Wolfgang Schuh, Fabien Agenès and Jörg Kirberg
    J Immunol August 15, 2014, 193 (4) 1737-1746; DOI: https://doi.org/10.4049/jimmunol.1302613

IMMUNE SYSTEM DEVELOPMENT

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    Adipocyte IL-15 Regulates Local and Systemic NK Cell Development
    Yae-Huei Liou, Szu-Wen Wang, Chin-Ling Chang, Po-Lin Huang, Mau-Sheng Hou, Yein-Gei Lai, Gilbert Aaron Lee, Si-Tse Jiang, Ching-Yen Tsai and Nan-Shih Liao
    J Immunol August 15, 2014, 193 (4) 1747-1758; DOI: https://doi.org/10.4049/jimmunol.1400868
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    Mammalian Target of Rapamycin Complex 1 Orchestrates Invariant NKT Cell Differentiation and Effector Function
    Lianjun Zhang, Benjamin O. Tschumi, Stéphanie Corgnac, Markus A. Rüegg, Michael N. Hall, Jean-Pierre Mach, Pedro Romero and Alena Donda
    J Immunol August 15, 2014, 193 (4) 1759-1765; DOI: https://doi.org/10.4049/jimmunol.1400769
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    A Reporter Mouse Reveals Lineage-Specific and Heterogeneous Expression of IRF8 during Lymphoid and Myeloid Cell Differentiation
    Hongsheng Wang, Ming Yan, Jiafang Sun, Shweta Jain, Ryusuke Yoshimi, Sanaz Momben Abolfath, Keiko Ozato, William G. Coleman Jr., Ashley P. Ng, Donald Metcalf, Ladina DiRago, Stephen L. Nutt and Herbert C. Morse III
    J Immunol August 15, 2014, 193 (4) 1766-1777; DOI: https://doi.org/10.4049/jimmunol.1301939
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    The Ability To Rearrange Dual TCRs Enhances Positive Selection, Leading to Increased Allo- and Autoreactive T Cell Repertoires
    Peggy P. Ni, Benjamin Solomon, Chyi-Song Hsieh, Paul M. Allen and Gerald P. Morris
    J Immunol August 15, 2014, 193 (4) 1778-1786; DOI: https://doi.org/10.4049/jimmunol.1400532

IMMUNOTHERAPY AND VACCINES

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    Antigen Targeting to CD11b+ Dendritic Cells in Association with TLR4/TRIF Signaling Promotes Strong CD8+ T Cell Responses
    Gilles Dadaglio, Catherine Fayolle, Xiaoming Zhang, Bernard Ryffel, Marine Oberkampf, Tristan Felix, Sandra Hervas-Stubbs, Radim Osicka, Peter Sebo, Daniel Ladant and Claude Leclerc
    J Immunol August 15, 2014, 193 (4) 1787-1798; DOI: https://doi.org/10.4049/jimmunol.1302974
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    Aerosol Vaccination with AERAS-402 Elicits Robust Cellular Immune Responses in the Lungs of Rhesus Macaques but Fails To Protect against High-Dose Mycobacterium tuberculosis Challenge
    Patricia A. Darrah, Diane L. Bolton, Andrew A. Lackner, Deepak Kaushal, Pyone Pyone Aye, Smriti Mehra, James L. Blanchard, Peter J. Didier, Chad J. Roy, Srinivas S. Rao, David A. Hokey, Charles A. Scanga, Donata R. Sizemore, Jerald C. Sadoff, Mario Roederer and Robert A. Seder
    J Immunol August 15, 2014, 193 (4) 1799-1811; DOI: https://doi.org/10.4049/jimmunol.1400676
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    T Cell Antigen Discovery Using Soluble Vaccinia Proteome Reveals Recognition of Antigens with Both Virion and Nonvirion Association
    D. Huw Davies, Sookhee Chun, Gary Hermanson, Jo Anne Tucker, Aarti Jain, Rie Nakajima, Jozelyn Pablo, Philip L. Felgner and Xiaowu Liang
    J Immunol August 15, 2014, 193 (4) 1812-1827; DOI: https://doi.org/10.4049/jimmunol.1400663
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    Fcγ Receptor Dependency of Agonistic CD40 Antibody in Lymphoma Therapy Can Be Overcome through Antibody Multimerization
    Ann L. White, Lang Dou, H. T. Claude Chan, Vikki L. Field, C. Ian Mockridge, Kane Moss, Emily L. Williams, Steven G. Booth, Ruth R. French, Elizabeth A. Potter, Cherié Butts, Aymen Al-Shamkhani, Mark S. Cragg, J. Sjef Verbeek, Peter W. M. Johnson, Martin J. Glennie and Stephen A. Beers
    J Immunol August 15, 2014, 193 (4) 1828-1835; DOI: https://doi.org/10.4049/jimmunol.1303204
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    The Effect of Adjuvanting Cancer Vaccines with Herpes Simplex Virus Glycoprotein D on Melanoma-Driven CD8+ T Cell Exhaustion
    Ying Zhang and Hildegund C. J. Ertl
    J Immunol August 15, 2014, 193 (4) 1836-1846; DOI: https://doi.org/10.4049/jimmunol.1302029
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    IL-2 Induction of Blimp-1 Is a Key In Vivo Signal for CD8+ Short-Lived Effector T Cell Differentiation
    Salix Boulet, Jean-François Daudelin and Nathalie Labrecque
    J Immunol August 15, 2014, 193 (4) 1847-1854; DOI: https://doi.org/10.4049/jimmunol.1302365

INFECTIOUS DISEASE AND HOST RESPONSE

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    Inhibition of the Classical Pathway of Complement by Meningococcal Capsular Polysaccharides
    Sarika Agarwal, Shreekant Vasudhev, Rosane B. DeOliveira and Sanjay Ram
    J Immunol August 15, 2014, 193 (4) 1855-1863; DOI: https://doi.org/10.4049/jimmunol.1303177
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    Platelet Activation and Apoptosis Modulate Monocyte Inflammatory Responses in Dengue
    Eugenio D. Hottz, Isabel M. Medeiros-de-Moraes, Adriana Vieira-de-Abreu, Edson F. de Assis, Rogério Vals-de-Souza, Hugo C. Castro-Faria-Neto, Andrew S. Weyrich, Guy A. Zimmerman, Fernando A. Bozza and Patrícia T. Bozza
    J Immunol August 15, 2014, 193 (4) 1864-1872; DOI: https://doi.org/10.4049/jimmunol.1400091
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    Antigen-Specific Naive CD8+ T Cells Produce a Single Pulse of IFN-γ In Vivo within Hours of Infection, but without Antiviral Effect
    Martin P. Hosking, Claudia T. Flynn and J. Lindsay Whitton
    J Immunol August 15, 2014, 193 (4) 1873-1885; DOI: https://doi.org/10.4049/jimmunol.1400348
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    Does β-Hexosaminidase Function Only as a Degranulation Indicator in Mast Cells? The Primary Role of β-Hexosaminidase in Mast Cell Granules
    Nobuyuki Fukuishi, Shinya Murakami, Akane Ohno, Naoya Yamanaka, Nobuaki Matsui, Kenji Fukutsuji, Sakuo Yamada, Kouji Itoh and Masaaki Akagi
    J Immunol August 15, 2014, 193 (4) 1886-1894; DOI: https://doi.org/10.4049/jimmunol.1302520
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    CCR5 Knockout Prevents Neuronal Injury and Behavioral Impairment Induced in a Transgenic Mouse Model by a CXCR4-Using HIV-1 Glycoprotein 120
    Ricky Maung, Melanie M. Hoefer, Ana B. Sanchez, Natalia E. Sejbuk, Kathryn E. Medders, Maya K. Desai, Irene C. Catalan, Cari C. Dowling, Cyrus M. de Rozieres, Gwenn A. Garden, Rossella Russo, Amanda J. Roberts, Roy Williams and Marcus Kaul
    J Immunol August 15, 2014, 193 (4) 1895-1910; DOI: https://doi.org/10.4049/jimmunol.1302915

INNATE IMMUNITY AND INFLAMMATION

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    TRIL Is Involved in Cytokine Production in the Brain following Escherichia coli Infection
    Paulina Wochal, Vijay A. K. Rathinam, Aisling Dunne, Thaddeus Carlson, Wen Kuang, Katherine J. Seidl, J. Perry Hall, Lih-Ling Lin, Mary Collins, Stefan A. Schattgen, Christopher R. MacKay, Caio T. Fagundes, Susan Carpenter, Katherine A. Fitzgerald and Luke A. J. O’Neill
    J Immunol August 15, 2014, 193 (4) 1911-1919; DOI: https://doi.org/10.4049/jimmunol.1302392
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    Enhancement of Adaptive Immunity by the Human Vaccine Adjuvant AS01 Depends on Activated Dendritic Cells
    Arnaud M. Didierlaurent, Catherine Collignon, Patricia Bourguignon, Sandrine Wouters, Kaat Fierens, Michel Fochesato, Najoua Dendouga, Christelle Langlet, Bernard Malissen, Bart N. Lambrecht, Nathalie Garçon, Marcelle Van Mechelen and Sandra Morel
    J Immunol August 15, 2014, 193 (4) 1920-1930; DOI: https://doi.org/10.4049/jimmunol.1400948
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    Differential Role for p120-Catenin in Regulation of TLR4 Signaling in Macrophages
    Zhiyong Yang, Dong Sun, Zhibo Yan, Albert B. Reynolds, John W. Christman, Richard D. Minshall, Asrar B. Malik, Yang Zhang and Guochang Hu
    J Immunol August 15, 2014, 193 (4) 1931-1941; DOI: https://doi.org/10.4049/jimmunol.1302863
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    Myeloid-Derived Suppressor Cells Are Involved in Lysosomal Acid Lipase Deficiency–Induced Endothelial Cell Dysfunctions
    Ting Zhao, Xinchun Ding, Hong Du and Cong Yan
    J Immunol August 15, 2014, 193 (4) 1942-1953; DOI: https://doi.org/10.4049/jimmunol.1301941
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    Immobilized Immune Complexes Induce Neutrophil Extracellular Trap Release by Human Neutrophil Granulocytes via FcγRIIIB and Mac-1
    Martina Behnen, Christoph Leschczyk, Sonja Möller, Tobit Batel, Matthias Klinger, Werner Solbach and Tamás Laskay
    J Immunol August 15, 2014, 193 (4) 1954-1965; DOI: https://doi.org/10.4049/jimmunol.1400478
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    Neutrophils Exhibit Differential Requirements for Homing Molecules in Their Lymphatic and Blood Trafficking into Draining Lymph Nodes
    Carolina V. Gorlino, Romina P. Ranocchia, María F. Harman, Iris A. García, María I. Crespo, Gabriel Morón, Belkys A. Maletto and María C. Pistoresi-Palencia
    J Immunol August 15, 2014, 193 (4) 1966-1974; DOI: https://doi.org/10.4049/jimmunol.1301791
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    Moderate Alcohol Induces Stress Proteins HSF1 and hsp70 and Inhibits Proinflammatory Cytokines Resulting in Endotoxin Tolerance
    Sujatha Muralidharan, Aditya Ambade, Melissa A. Fulham, Janhavee Deshpande, Donna Catalano and Pranoti Mandrekar
    J Immunol August 15, 2014, 193 (4) 1975-1987; DOI: https://doi.org/10.4049/jimmunol.1303468
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    Cell Cycle Control and HIV-1 Susceptibility Are Linked by CDK6-Dependent CDK2 Phosphorylation of SAMHD1 in Myeloid and Lymphoid Cells
    Eduardo Pauls, Alba Ruiz, Roger Badia, Marc Permanyer, Albert Gubern, Eva Riveira-Muñoz, Javier Torres-Torronteras, Mar Álvarez, Beatriz Mothe, Christian Brander, Manel Crespo, Luis Menéndez-Arias, Bonaventura Clotet, Oliver T. Keppler, Ramon Martí, Francesc Posas, Ester Ballana and José A. Esté
    J Immunol August 15, 2014, 193 (4) 1988-1997; DOI: https://doi.org/10.4049/jimmunol.1400873

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Structure of the Superantigen Staphylococcal Enterotoxin B in Complex with TCR and Peptide–MHC Demonstrates Absence of TCR–Peptide Contacts
    Karin E. J. Rödström, Karin Elbing and Karin Lindkvist-Petersson
    J Immunol August 15, 2014, 193 (4) 1998-2004; DOI: https://doi.org/10.4049/jimmunol.1401268

TRANSPLANTATION

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    MHC-Mismatched Chimerism Is Required for Induction of Transplantation Tolerance in Autoimmune Nonobese Diabetic Recipients
    Miao Wang, Jeremy Racine, Mingfeng Zhang, Tao Wu, Ruishu Deng, Heather Johnston, Christine Shen, Kathleen Siswanto and Defu Zeng
    J Immunol August 15, 2014, 193 (4) 2005-2015; DOI: https://doi.org/10.4049/jimmunol.1401137

TUMOR IMMUNOLOGY

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    NK Cells Are the Crucial Antitumor Mediators When STAT3-Mediated Immunosuppression Is Blocked in Hepatocellular Carcinoma
    Qiangjun Sui, Jian Zhang, Xiaoxia Sun, Cai Zhang, Qiuju Han and Zhigang Tian
    J Immunol August 15, 2014, 193 (4) 2016-2023; DOI: https://doi.org/10.4049/jimmunol.1302389
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    Therapy of Peritoneally Disseminated Colon Cancer by TAP-Deficient Embryonic Stem Cell–Derived Macrophages in Allogeneic Recipients
    Eriko Haga, Yuko Endo, Miwa Haruta, Chihiro Koba, Keiko Matsumura, Koutaro Takamatsu, Tokunori Ikeda, Yasuharu Nishimura and Satoru Senju
    J Immunol August 15, 2014, 193 (4) 2024-2033; DOI: https://doi.org/10.4049/jimmunol.1303473
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The Journal of Immunology: 193 (4)
The Journal of Immunology
Vol. 193, Issue 4
15 Aug 2014
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  • TRANSLATING IMMUNOLOGY
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606