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The Journal of Immunology

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Table of Contents

April 15, 2014; Volume 192,Issue 8

IN THIS ISSUE

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    In This Issue

    Remodeling with ORMDL3 See article p. 3475

    Reprogramming B Cells See article p. 3626

    Seq-ing Diversity in HIV Antibodies See article p. 3637

    Stressing about Viruses See article p. 3753

    Shedding Light on Cervical HIV See article p. 3947

    J Immunol April 15, 2014, 192 (8) 3453-3454; DOI: https://doi.org/10.4049/jimmunol.1490010

BRIEF REVIEWS

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    The Drosophila Imd Signaling Pathway
    Henna Myllymäki, Susanna Valanne and Mika Rämet
    J Immunol April 15, 2014, 192 (8) 3455-3462; DOI: https://doi.org/10.4049/jimmunol.1303309

CUTTING EDGE

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    Cutting Edge: A Double-Mutant Knockin of the CD28 YMNM and PYAP Motifs Reveals a Critical Role for the YMNM Motif in Regulation of T Cell Proliferation and Bcl-xL Expression
    Jonathan S. Boomer, Christine M. Deppong, Dulari D. Shah, Traci L. Bricker and Jonathan M. Green
    J Immunol April 15, 2014, 192 (8) 3465-3469; DOI: https://doi.org/10.4049/jimmunol.1301240
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    Cutting Edge: Flt3 Ligand Mediates STAT3-Independent Expansion but STAT3-Dependent Activation of Myeloid-Derived Suppressor Cells
    Brian R. Rosborough, Lisa R. Mathews, Benjamin M. Matta, Quan Liu, Dàlia Raïch-Regué, Angus W. Thomson and Hēth R. Turnquist
    J Immunol April 15, 2014, 192 (8) 3470-3473; DOI: https://doi.org/10.4049/jimmunol.1300058

ALLERGY AND OTHER HYPERSENSITIVITIES

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    ORMDL3 Transgenic Mice Have Increased Airway Remodeling and Airway Responsiveness Characteristic of Asthma
    Marina Miller, Peter Rosenthal, Andrew Beppu, James L. Mueller, Hal M. Hoffman, Arvin B. Tam, Taylor A. Doherty, Matthew D. McGeough, Carla A. Pena, Maho Suzukawa, Maho Niwa and David H. Broide
    J Immunol April 15, 2014, 192 (8) 3475-3487; DOI: https://doi.org/10.4049/jimmunol.1303047
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    Signal-Transducing Adaptor Protein-2 Controls the IgE-Mediated, Mast Cell–Mediated Anaphylactic Responses
    Yuichi Sekine, Keigo Nishida, Satoru Yamasaki, Ryuta Muromoto, Shigeyuki Kon, Jun-ichi Kashiwakura, Kodai Saitoh, Sumihito Togi, Akihiko Yoshimura, Kenji Oritani and Tadashi Matsuda
    J Immunol April 15, 2014, 192 (8) 3488-3495; DOI: https://doi.org/10.4049/jimmunol.1300886

ANTIGEN RECOGNITION AND RESPONSES

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    Sequence-Specific Alterations of Epitope Production by HIV Protease Inhibitors
    Georgio Kourjian, Yang Xu, Ijah Mondesire-Crump, Mariko Shimada, Pauline Gourdain and Sylvie Le Gall
    J Immunol April 15, 2014, 192 (8) 3496-3506; DOI: https://doi.org/10.4049/jimmunol.1302805
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    Differential Kinetics of Antigen Dependency of CD4+ and CD8+ T Cells
    Hannah Rabenstein, Anne C. Behrendt, Joachim W. Ellwart, Ronald Naumann, Marion Horsch, Johannes Beckers and Reinhard Obst
    J Immunol April 15, 2014, 192 (8) 3507-3517; DOI: https://doi.org/10.4049/jimmunol.1302725

AUTOIMMUNITY

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    Regulation of Experimental Autoimmune Encephalomyelitis by TPL-2 Kinase
    Srividya Sriskantharajah, Eva Gückel, Niki Tsakiri, Katrin Kierdorf, Christine Brender, Abduelhakem Ben-Addi, Marc Veldhoen, Philip N. Tsichlis, Brigitta Stockinger, Anne O’Garra, Marco Prinz, George Kollias and Steven C. Ley
    J Immunol April 15, 2014, 192 (8) 3518-3529; DOI: https://doi.org/10.4049/jimmunol.1300172

IMMUNE REGULATION

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    Sulforaphane Protects from T Cell–Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells
    Julia Geisel, Jürgen Brück, Ivana Glocova, Katja Dengler, Tobias Sinnberg, Oliver Rothfuss, Michael Walter, Klaus Schulze-Osthoff, Martin Röcken and Kamran Ghoreschi
    J Immunol April 15, 2014, 192 (8) 3530-3539; DOI: https://doi.org/10.4049/jimmunol.1300556
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    Urokinase Plasminogen Activator Is a Central Regulator of Macrophage Three-Dimensional Invasion, Matrix Degradation, and Adhesion
    Andrew J. Fleetwood, Adrian Achuthan, Heidi Schultz, Anneline Nansen, Kasper Almholt, Pernille Usher and John A. Hamilton
    J Immunol April 15, 2014, 192 (8) 3540-3547; DOI: https://doi.org/10.4049/jimmunol.1302864
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    Eosinophils Regulate Peripheral B Cell Numbers in Both Mice and Humans
    Tina W. Wong, Alfred D. Doyle, James J. Lee and Diane F. Jelinek
    J Immunol April 15, 2014, 192 (8) 3548-3558; DOI: https://doi.org/10.4049/jimmunol.1302241
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    Dendritic Cell Motility and T Cell Activation Requires Regulation of Rho-Cofilin Signaling by the Rho-GTPase Activating Protein Myosin IXb
    Yan Xu, Stefanie Pektor, Sandra Balkow, Sandra A. Hemkemeyer, Zhijun Liu, Kay Grobe, Peter J. Hanley, Limei Shen, Matthias Bros, Talkea Schmidt, Martin Bähler and Stephan Grabbe
    J Immunol April 15, 2014, 192 (8) 3559-3568; DOI: https://doi.org/10.4049/jimmunol.1300695
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    Axl Receptor Blockade Ameliorates Pulmonary Pathology Resulting from Primary Viral Infection and Viral Exacerbation of Asthma
    Takehiko Shibata, David M. Habiel, Ana L. Coelho, Steven L. Kunkel, Nicholas W. Lukacs and Cory M. Hogaboam
    J Immunol April 15, 2014, 192 (8) 3569-3581; DOI: https://doi.org/10.4049/jimmunol.1302766
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    Impaired B Cell Receptor Signaling Is Responsible for Reduced TACI Expression and Function in X-Linked Immunodeficient Mice
    Kadriye Uslu, Adam S. Coleman, Windy R. Allman, Nora Katsenelson, Richard J. Bram, Kishore R. Alugupalli and Mustafa Akkoyunlu
    J Immunol April 15, 2014, 192 (8) 3582-3595; DOI: https://doi.org/10.4049/jimmunol.1203468
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    IFN-λ Exerts Opposing Effects on T Cell Responses Depending on the Chronicity of the Virus Infection
    Ichiro Misumi and Jason K. Whitmire
    J Immunol April 15, 2014, 192 (8) 3596-3606; DOI: https://doi.org/10.4049/jimmunol.1301705
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    B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation
    Lisa G. Barnett, Helen M. A. Simkins, Burton E. Barnett, Lisa L. Korn, Andy L. Johnson, E. John Wherry, Gregory F. Wu and Terri M. Laufer
    J Immunol April 15, 2014, 192 (8) 3607-3617; DOI: https://doi.org/10.4049/jimmunol.1301284
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    Polymicrobial Sepsis Alters Antigen-Dependent and -Independent Memory CD8 T Cell Functions
    Sean Duong, Stephanie A. Condotta, Deepa Rai, Matthew D. Martin, Thomas S. Griffith and Vladimir P. Badovinac
    J Immunol April 15, 2014, 192 (8) 3618-3625; DOI: https://doi.org/10.4049/jimmunol.1303460
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    Metabolic Reprogramming Is Required for Antibody Production That Is Suppressed in Anergic but Exaggerated in Chronically BAFF-Exposed B Cells
    Alfredo Caro-Maldonado, Ruoning Wang, Amanda G. Nichols, Masayuki Kuraoka, Sandra Milasta, Lillian D. Sun, Amanda L. Gavin, E. Dale Abel, Garnett Kelsoe, Douglas R. Green and Jeffrey C. Rathmell
    J Immunol April 15, 2014, 192 (8) 3626-3636; DOI: https://doi.org/10.4049/jimmunol.1302062

IMMUNOGENETICS

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    Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization
    Christopher Sundling, Zhenhai Zhang, Ganesh E. Phad, Zizhang Sheng, Yimeng Wang, John R. Mascola, Yuxing Li, Richard T. Wyatt, Lawrence Shapiro and Gunilla B. Karlsson Hedestam
    J Immunol April 15, 2014, 192 (8) 3637-3644; DOI: https://doi.org/10.4049/jimmunol.1303334
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    Iddm30 Controls Pancreatic Expression of Ccl11 (Eotaxin) and the Th1/Th2 Balance within the Insulitic Lesions
    Gary Y. C. Chao, Robert H. Wallis, Leili Marandi, Terri Ning, Janice Sarmiento, Andrew D. Paterson and Philippe Poussier
    J Immunol April 15, 2014, 192 (8) 3645-3653; DOI: https://doi.org/10.4049/jimmunol.1302383

IMMUNOTHERAPY AND VACCINES

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    Differential Role of Th1 and Th2 Cytokines in Autotoxicity Driven by CD19-Specific Second-Generation Chimeric Antigen Receptor T Cells in a Mouse Model
    Eleanor J. Cheadle, Victoria Sheard, Dominic G. Rothwell, John S. Bridgeman, Garry Ashton, Vivien Hanson, A. Wasat Mansoor, Robert E. Hawkins and David E. Gilham
    J Immunol April 15, 2014, 192 (8) 3654-3665; DOI: https://doi.org/10.4049/jimmunol.1302148
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    Incorporation of CpG into a Liposomal Vaccine Formulation Increases the Maturation of Antigen-Loaded Dendritic Cells and Monocytes To Improve Local and Systemic Immunity
    Melanie R. Neeland, Martin J. Elhay, Jackie Nathanielsz, Els N. T. Meeusen and Michael J. de Veer
    J Immunol April 15, 2014, 192 (8) 3666-3675; DOI: https://doi.org/10.4049/jimmunol.1303014

INFECTIOUS DISEASE AND HOST RESPONSE

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    Distinct Requirements for Activation of NKT and NK Cells during Viral Infection
    Aaron J. Tyznik, Shilpi Verma, Qiao Wang, Mitchell Kronenberg and Chris A. Benedict
    J Immunol April 15, 2014, 192 (8) 3676-3685; DOI: https://doi.org/10.4049/jimmunol.1300837
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    MAPK Phosphotase 5 Deficiency Contributes to Protection against Blood-Stage Plasmodium yoelii 17XL Infection in Mice
    Qianqian Cheng, Qingfeng Zhang, Xindong Xu, Lan Yin, Lin Sun, Xin Lin, Chen Dong and Weiqing Pan
    J Immunol April 15, 2014, 192 (8) 3686-3696; DOI: https://doi.org/10.4049/jimmunol.1301863
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    Staphylococcus aureus Infection of Mice Expands a Population of Memory γδ T Cells That Are Protective against Subsequent Infection
    Alison G. Murphy, Kate M. O’Keeffe, Stephen J. Lalor, Belinda M. Maher, Kingston H. G. Mills and Rachel M. McLoughlin
    J Immunol April 15, 2014, 192 (8) 3697-3708; DOI: https://doi.org/10.4049/jimmunol.1303420
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    Tissue Requirements for Establishing Long-Term CD4+ T Cell–Mediated Immunity following Leishmania donovani Infection
    Patrick T. Bunn, Amanda C. Stanley, Fabian de Labastida Rivera, Alexander Mulherin, Meru Sheel, Clare E. Alexander, Rebecca J. Faleiro, Fiona H. Amante, Marcela Montes De Oca, Shannon E. Best, Kylie R. James, Paul M. Kaye, Ashraful Haque and Christian R. Engwerda
    J Immunol April 15, 2014, 192 (8) 3709-3718; DOI: https://doi.org/10.4049/jimmunol.1300768
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    BAFF and BAFF Receptor Levels Correlate with B Cell Subset Activation and Redistribution in Controlled Human Malaria Infection
    Anja Scholzen, Anne C. Teirlinck, Else M. Bijker, Meta Roestenberg, Cornelus C. Hermsen, Stephen L. Hoffman and Robert W. Sauerwein
    J Immunol April 15, 2014, 192 (8) 3719-3729; DOI: https://doi.org/10.4049/jimmunol.1302960
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    Functional Characterization of Ocular-Derived Human Alphaherpesvirus Cross-Reactive CD4 T Cells
    Werner J. D. Ouwendijk, Annemieke Geluk, Saskia L. Smits, Sarah Getu, Albert D. M. E. Osterhaus and Georges M. G. M. Verjans
    J Immunol April 15, 2014, 192 (8) 3730-3739; DOI: https://doi.org/10.4049/jimmunol.1302307
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    Humoral Immunity and CD4+ Th1 Cells Are Both Necessary for a Fully Protective Immune Response upon Secondary Infection with Brucella melitensis
    Marie-Alice Vitry, Delphine Hanot Mambres, Carl De Trez, Shizuo Akira, Bernhard Ryffel, Jean-Jacques Letesson and Eric Muraille
    J Immunol April 15, 2014, 192 (8) 3740-3752; DOI: https://doi.org/10.4049/jimmunol.1302561
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    NF90 Exerts Antiviral Activity through Regulation of PKR Phosphorylation and Stress Granules in Infected Cells
    Xi Wen, Xiaofeng Huang, Bobo Wing-Yee Mok, Yixin Chen, Min Zheng, Siu-Ying Lau, Pui Wang, Wenjun Song, Dong-Yan Jin, Kwok-Yung Yuen and Honglin Chen
    J Immunol April 15, 2014, 192 (8) 3753-3764; DOI: https://doi.org/10.4049/jimmunol.1302813

INNATE IMMUNITY AND INFLAMMATION

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    Resolvin D1 Stimulates Alveolar Fluid Clearance through Alveolar Epithelial Sodium Channel, Na,K-ATPase via ALX/cAMP/PI3K Pathway in Lipopolysaccharide-Induced Acute Lung Injury
    Qian Wang, Xia Zheng, Yang Cheng, Yi-Lan Zhang, Hai-Xu Wen, Zhen Tao, Hui Li, Yu Hao, Ye Gao, Liang-Min Yang, Fang Gao Smith, Chang-Jiang Huang and Sheng-Wei Jin
    J Immunol April 15, 2014, 192 (8) 3765-3777; DOI: https://doi.org/10.4049/jimmunol.1302421
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    Myeloid-Derived Suppressor Cells Contribute to Staphylococcus aureus Orthopedic Biofilm Infection
    Cortney E. Heim, Debbie Vidlak, Tyler D. Scherr, Jessica A. Kozel, Melissa Holzapfel, David E. Muirhead and Tammy Kielian
    J Immunol April 15, 2014, 192 (8) 3778-3792; DOI: https://doi.org/10.4049/jimmunol.1303408
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    IFN-γ or IFN-α Ameliorates Chronic Proliferative Dermatitis by Inducing Expression of Linear Ubiquitin Chain Assembly Complex
    Hironari Tamiya, Mika Terao, Tsuyoshi Takiuchi, Masaki Nakahara, Yoshiteru Sasaki, Ichiro Katayama, Hideki Yoshikawa and Kazuhiro Iwai
    J Immunol April 15, 2014, 192 (8) 3793-3804; DOI: https://doi.org/10.4049/jimmunol.1302308
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    CD56brightPerforinlow Noncytotoxic Human NK Cells Are Abundant in Both Healthy and Neoplastic Solid Tissues and Recirculate to Secondary Lymphoid Organs via Afferent Lymph
    Paolo Carrega, Irene Bonaccorsi, Emma Di Carlo, Barbara Morandi, Petra Paul, Valeria Rizzello, Giuseppe Cipollone, Giuseppe Navarra, Maria Cristina Mingari, Lorenzo Moretta and Guido Ferlazzo
    J Immunol April 15, 2014, 192 (8) 3805-3815; DOI: https://doi.org/10.4049/jimmunol.1301889
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    CCL3 Production by Microglial Cells Modulates Disease Severity in Murine Models of Retinal Degeneration
    Hideo Kohno, Tadao Maeda, Lindsay Perusek, Eric Pearlman and Akiko Maeda
    J Immunol April 15, 2014, 192 (8) 3816-3827; DOI: https://doi.org/10.4049/jimmunol.1301738
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    Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti–IL-17 Receptor Monoclonal Antibody
    Chris B. Russell, Hugh Rand, Jeannette Bigler, Keith Kerkof, Martin Timour, Edgar Bautista, James G. Krueger, David H. Salinger, Andrew A. Welcher and David A. Martin
    J Immunol April 15, 2014, 192 (8) 3828-3836; DOI: https://doi.org/10.4049/jimmunol.1301737
  • Open Access
    TNFR1/Phox Interaction and TNFR1 Mitochondrial Translocation Thwart Silica-Induced Pulmonary Fibrosis

    Author Choice Article

    Fabrizio Fazzi, Joel Njah, Michelangelo Di Giuseppe, Daniel E. Winnica, Kristina Go, Ernest Sala, Claudette M. St Croix, Simon C. Watkins, Vladimir A. Tyurin, Donald G. Phinney, Cheryl L. Fattman, George D. Leikauf, Valerian E. Kagan and Luis A. Ortiz
    J Immunol April 15, 2014, 192 (8) 3837-3846; DOI: https://doi.org/10.4049/jimmunol.1103516
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    Hepatic Stellate Cells Orchestrate Clearance of Necrotic Cells in a Hypoxia-Inducible Factor-1α–Dependent Manner by Modulating Macrophage Phenotype in Mice
    Akie Mochizuki, Aaron Pace, Cheryl E. Rockwell, Katherine J. Roth, Aaron Chow, Kate M. O’Brien, Ryan Albee, Kara Kelly, Keara Towery, James P. Luyendyk and Bryan L. Copple
    J Immunol April 15, 2014, 192 (8) 3847-3857; DOI: https://doi.org/10.4049/jimmunol.1303195
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    CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile
    Elena Sierra-Filardi, Concha Nieto, Ángeles Domínguez-Soto, Rubén Barroso, Paloma Sánchez-Mateos, Amaya Puig-Kroger, María López-Bravo, Jorge Joven, Carlos Ardavín, José L. Rodríguez-Fernández, Carmen Sánchez-Torres, Mario Mellado and Ángel L. Corbí
    J Immunol April 15, 2014, 192 (8) 3858-3867; DOI: https://doi.org/10.4049/jimmunol.1302821
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    NKp46+CD3+ Cells: A Novel Nonconventional T Cell Subset in Cattle Exhibiting Both NK Cell and T Cell Features
    Timothy K. Connelley, Cassandra Longhi, Alison Burrells, Kathryn Degnan, Jayne Hope, Alasdair J. Allan, John A. Hammond, Anne K. Storset and W. Ivan Morrison
    J Immunol April 15, 2014, 192 (8) 3868-3880; DOI: https://doi.org/10.4049/jimmunol.1302464
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    Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function
    Mohammed G. Ghonime, Obada R. Shamaa, Srabani Das, Ramadan A. Eldomany, Teresa Fernandes-Alnemri, Emad S. Alnemri, Mikhail A. Gavrilin and Mark D. Wewers
    J Immunol April 15, 2014, 192 (8) 3881-3888; DOI: https://doi.org/10.4049/jimmunol.1301974
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    Functional NK Cell Repertoires Are Maintained through IL-2Rα and Fas Ligand
    Martin Felices, Todd R. Lenvik, Dave E. M. Ankarlo, Bree Foley, Julie Curtsinger, Xianghua Luo, Bruce R. Blazar, Stephen K. Anderson and Jeffrey S. Miller
    J Immunol April 15, 2014, 192 (8) 3889-3897; DOI: https://doi.org/10.4049/jimmunol.1302601
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    Involvement of the 4-1BB/4-1BBL Pathway in Control of Monocyte Numbers by Invariant NKT Cells
    Suzanne L. Cole, Kambez H. Benam, Andrew J. McMichael and Ling-Pei Ho
    J Immunol April 15, 2014, 192 (8) 3898-3907; DOI: https://doi.org/10.4049/jimmunol.1302385

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Chemokine Cooperativity Is Caused by Competitive Glycosaminoglycan Binding
    Folkert Verkaar, Jody van Offenbeek, Miranda M. C. van der Lee, Lambertus H. C. J. van Lith, Anne O. Watts, Angelique L. W. M. M. Rops, David C. Aguilar, Joshua J. Ziarek, Johan van der Vlag, Tracy M. Handel, Brian F. Volkman, Amanda E. I. Proudfoot, Henry F. Vischer, Guido J. R. Zaman and Martine J. Smit
    J Immunol April 15, 2014, 192 (8) 3908-3914; DOI: https://doi.org/10.4049/jimmunol.1302159
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    Gene Expression in the Gitr Locus Is Regulated by NF-κB and Foxp3 through an Enhancer
    Yukiko Tone, Yoko Kidani, Chihiro Ogawa, Kouhei Yamamoto, Masato Tsuda, Christian Peter, Herman Waldmann and Masahide Tone
    J Immunol April 15, 2014, 192 (8) 3915-3924; DOI: https://doi.org/10.4049/jimmunol.1302174
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    B Cell Differentiation Is Associated with Reprogramming the CCCTC Binding Factor–Dependent Chromatin Architecture of the Murine MHC Class II Locus
    Parimal Majumder, Christopher D. Scharer, Nancy M. Choi and Jeremy M. Boss
    J Immunol April 15, 2014, 192 (8) 3925-3935; DOI: https://doi.org/10.4049/jimmunol.1303205
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    Critical Roles for PU.1, GATA1, and GATA2 in the Expression of Human FcεRI on Mast Cells: PU.1 and GATA1 Transactivate FCER1A, and GATA2 Transactivates FCER1A and MS4A2
    Eisuke Inage, Kazumi Kasakura, Takuya Yashiro, Ryuyo Suzuki, Yosuke Baba, Nobuhiro Nakano, Mutsuko Hara, Atsushi Tanabe, Keisuke Oboki, Kenji Matsumoto, Hirohisa Saito, François Niyonsaba, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu and Chiharu Nishiyama
    J Immunol April 15, 2014, 192 (8) 3936-3946; DOI: https://doi.org/10.4049/jimmunol.1302366

MUCOSAL IMMUNOLOGY

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    Presence of CD8+ T Cells in the Ectocervical Mucosa Correlates with Genital Viral Shedding in HIV-Infected Women despite a Low Prevalence of HIV RNA–Expressing Cells in the Tissue
    Anna Gibbs, Taha Hirbod, Qingsheng Li, Karin Bohman, Terry B. Ball, Francis A. Plummer, Rupert Kaul, Joshua Kimani, Kristina Broliden and Annelie Tjernlund
    J Immunol April 15, 2014, 192 (8) 3947-3957; DOI: https://doi.org/10.4049/jimmunol.1302826
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    Innate PI3K p110δ Regulates Th1/Th17 Development and Microbiota-Dependent Colitis
    Erin C. Steinbach, Taku Kobayashi, Steven M. Russo, Shehzad Z. Sheikh, Gregory R. Gipson, Samantha T. Kennedy, Jennifer K. Uno, Yoshiyuki Mishima, Luke B. Borst, Bo Liu, Hans Herfarth, Jenny P. Y. Ting, R. Balfour Sartor and Scott E. Plevy
    J Immunol April 15, 2014, 192 (8) 3958-3968; DOI: https://doi.org/10.4049/jimmunol.1301533
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    IL-13 Orchestrates Resolution of Chronic Intestinal Inflammation via Phosphorylation of Glycogen Synthase Kinase-3β
    Stefan Fichtner-Feigl, Rebecca Kesselring, Maria Martin, Florian Obermeier, Petra Ruemmele, Atsushi Kitani, Stefan M. Brunner, Michael Haimerl, Edward K. Geissler, Warren Strober and Hans J. Schlitt
    J Immunol April 15, 2014, 192 (8) 3969-3980; DOI: https://doi.org/10.4049/jimmunol.1301072

TUMOR IMMUNOLOGY

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    Histone Deacetylase Inhibitor Sensitizes Apoptosis-Resistant Melanomas to Cytotoxic Human T Lymphocytes through Regulation of TRAIL/DR5 Pathway
    Ali R. Jazirehi, Siavash K. Kurdistani and James S. Economou
    J Immunol April 15, 2014, 192 (8) 3981-3989; DOI: https://doi.org/10.4049/jimmunol.1302532

CORRECTIONS

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    Correction: Oral Combined Therapy With Probiotics and Alloantigen Induces B Cell–Dependent Long-Lasting Specific Tolerance
    Ana C. T. Mercadante, Suelen M. Perobelli, Ana P. G. Alves, Triciana Gonçalves-Silva, Wallace Mello, Ana C. Gomes-Santos, Anderson Miyoshi, Ana M. C. Faria and Adriana Bonomo
    J Immunol April 15, 2014, 192 (8) 3990; DOI: https://doi.org/10.4049/jimmunol.1490007
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    Correction: H2S Increases Survival During Sepsis: Protective Effect of CHOP Inhibition
    Marcella Ferlito, Qihong Wang, William B. Fulton, Paul M. Colombani, Luigi Marchionni, Karen Fox-Talbot, Nazareno Paolocci and Charles Steenbergen
    J Immunol April 15, 2014, 192 (8) 3991; DOI: https://doi.org/10.4049/jimmunol.1490009
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    Correction: Peripheral Tissue Homing Receptors Enable T Cell Entry into Lymph Nodes and Affect the Anatomical Distribution of Memory Cells
    C. Colin Brinkman, Sherin J. Rouhani, Nithya Srinivasan and Victor H. Engelhard
    J Immunol April 15, 2014, 192 (8) 3992-3995; DOI: https://doi.org/10.4049/jimmunol.1490008
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The Journal of Immunology: 192 (8)
The Journal of Immunology
Vol. 192, Issue 8
15 Apr 2014
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  • IN THIS ISSUE
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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