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Table of Contents

January 15, 2014; Volume 192,Issue 2

IN THIS ISSUE

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    In This Issue

    Age and Infection Influence Immunity See article p. 603

    Insulin AKTs on Tregs See article p. 623

    Cooperative Costimulation in Thymus See article p. 630

    Tumor Ags Cross-Dress pDCs See article p. 824

    J Immunol January 15, 2014, 192 (2) 549-550; DOI: https://doi.org/10.4049/jimmunol.1390071

CUTTING EDGE

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    Cutting Edge: DNAX Accessory Molecule 1–Deficient CD8+ T Cells Display Immunological Synapse Defects That Impair Antitumor Immunity
    Kelly M. Ramsbottom, Edwin D. Hawkins, Raz Shimoni, Mairi McGrath, Christopher J. Chan, Sarah M. Russell, Mark J. Smyth and Jane Oliaro
    J Immunol January 15, 2014, 192 (2) 553-557; DOI: https://doi.org/10.4049/jimmunol.1302197

AUTOIMMUNITY

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    GM-CSF Modulates Autoantibody Production and Skin Blistering in Experimental Epidermolysis Bullosa Acquisita
    Unni Krishna S. R. L. Samavedam, Hiroaki Iwata, Susen Müller, Franziska S. Schulze, Andreas Recke, Enno Schmidt, Detlef Zillikens and Ralf J. Ludwig
    J Immunol January 15, 2014, 192 (2) 559-571; DOI: https://doi.org/10.4049/jimmunol.1301556
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    Effector-Memory T Cells Develop in Islets and Report Islet Pathology in Type 1 Diabetes
    Jonathan Chee, Hyun-Ja Ko, Ania Skowera, Gaurang Jhala, Tara Catterall, Kate L. Graham, Robyn M. Sutherland, Helen E. Thomas, Andrew M. Lew, Mark Peakman, Thomas W. H. Kay and Balasubramanian Krishnamurthy
    J Immunol January 15, 2014, 192 (2) 572-580; DOI: https://doi.org/10.4049/jimmunol.1302100
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    Lack of Galactosylation Enhances the Pathogenic Activity of IgG1 but Not IgG2a Anti-Erythrocyte Autoantibodies
    Kiyoaki Ito, Jun-ichi Furukawa, Kazunori Yamada, Ngoc Lan Tran, Yasuro Shinohara and Shozo Izui
    J Immunol January 15, 2014, 192 (2) 581-588; DOI: https://doi.org/10.4049/jimmunol.1302488

CLINICAL AND HUMAN IMMUNOLOGY

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    IL-32 Promotes Angiogenesis
    Claudia A. Nold-Petry, Ina Rudloff, Yvonne Baumer, Menotti Ruvo, Daniela Marasco, Paolo Botti, Laszlo Farkas, Steven X. Cho, Jarod A. Zepp, Tania Azam, Hannah Dinkel, Brent E. Palmer, William A. Boisvert, Carlyne D. Cool, Laima Taraseviciene-Stewart, Bas Heinhuis, Leo A. B. Joosten, Charles A. Dinarello, Norbert F. Voelkel and Marcel F. Nold
    J Immunol January 15, 2014, 192 (2) 589-602; DOI: https://doi.org/10.4049/jimmunol.1202802
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    Effects of Aging, Cytomegalovirus Infection, and EBV Infection on Human B Cell Repertoires
    Chen Wang, Yi Liu, Lan T. Xu, Katherine J. L. Jackson, Krishna M. Roskin, Tho D. Pham, Jonathan Laserson, Eleanor L. Marshall, Katie Seo, Ji-Yeun Lee, David Furman, Daphne Koller, Cornelia L. Dekker, Mark M. Davis, Andrew Z. Fire and Scott D. Boyd
    J Immunol January 15, 2014, 192 (2) 603-611; DOI: https://doi.org/10.4049/jimmunol.1301384

IMMUNE REGULATION

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    Aged Mice Are Unable To Mount an Effective Myeloid Response to Sepsis
    Dina C. Nacionales, Lori F. Gentile, Erin Vanzant, M. Cecilia Lopez, Angela Cuenca, Alex G. Cuenca, Ricardo Ungaro, Yi Li, Tezcan Ozrazgat Baslanti, Azra Bihorac, Frederick A. Moore, Henry V. Baker, Christiaan Leeuwenburgh, Lyle L. Moldawer and Philip A. Efron
    J Immunol January 15, 2014, 192 (2) 612-622; DOI: https://doi.org/10.4049/jimmunol.1302109
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    Insulin Inhibits IL-10–Mediated Regulatory T Cell Function: Implications for Obesity
    Jonathan M. Han, Scott J. Patterson, Madeleine Speck, Jan A. Ehses and Megan K. Levings
    J Immunol January 15, 2014, 192 (2) 623-629; DOI: https://doi.org/10.4049/jimmunol.1302181

IMMUNE SYSTEM DEVELOPMENT

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    Thymic Medullary Epithelium and Thymocyte Self-Tolerance Require Cooperation between CD28–CD80/86 and CD40–CD40L Costimulatory Pathways
    Joy A. Williams, Jingjing Zhang, Hyein Jeon, Takeshi Nitta, Izumi Ohigashi, David Klug, Michael J. Kruhlak, Baishakhi Choudhury, Susan O. Sharrow, Larry Granger, Anthony Adams, Michael A. Eckhaus, S. Rhiannon Jenkinson, Ellen R. Richie, Ronald E. Gress, Yousuke Takahama and Richard J. Hodes
    J Immunol January 15, 2014, 192 (2) 630-640; DOI: https://doi.org/10.4049/jimmunol.1302550

IMMUNOTHERAPY AND VACCINES

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    HLA Micropolymorphisms Strongly Affect Peptide–MHC Multimer–Based Monitoring of Antigen-Specific CD8+ T Cell Responses
    Marit M. van Buuren, Feline E. Dijkgraaf, Carsten Linnemann, Mireille Toebes, Cynthia X. L. Chang, Juk Yee Mok, Melanie Nguyen, Wim J. E. van Esch, Pia Kvistborg, Gijsbert M. Grotenbreg and Ton N. M. Schumacher
    J Immunol January 15, 2014, 192 (2) 641-648; DOI: https://doi.org/10.4049/jimmunol.1301770
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    KLRG1 Impairs CD4+ T Cell Responses via p16ink4a and p27kip1 Pathways: Role in Hepatitis B Vaccine Failure in Individuals with Hepatitis C Virus Infection
    Lei Shi, Jia M. Wang, Jun P. Ren, Yong Q. Cheng, Ruo S. Ying, Xiao Y. Wu, Shu M. Lin, Jeddidiah W. D. Griffin, Guang Y. Li, Jonathan P. Moorman and Zhi Q. Yao
    J Immunol January 15, 2014, 192 (2) 649-657; DOI: https://doi.org/10.4049/jimmunol.1302069
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    Novel Mechanisms Underlying the Immediate and Transient Global Tolerization of Splenic Dendritic Cells after Vaccination with a Self-Antigen
    Adam M. Farkas and Olivera J. Finn
    J Immunol January 15, 2014, 192 (2) 658-665; DOI: https://doi.org/10.4049/jimmunol.1301904

INFECTIOUS DISEASE AND HOST RESPONSE

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    Role for σ38 in Prolonged Survival of Escherichia coli in Drosophila melanogaster
    Akiko Shiratsuchi, Naoto Shimamoto, Mao Nitta, Tran Quoc Tuan, Afwa Firdausi, Mitsuko Gawasawa, Kaneyoshi Yamamoto, Akira Ishihama and Yoshinobu Nakanishi
    J Immunol January 15, 2014, 192 (2) 666-675; DOI: https://doi.org/10.4049/jimmunol.1300968
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    Role of IL-6 in Mycobacterium avium–Associated Immune Reconstitution Inflammatory Syndrome
    Daniel L. Barber, Bruno B. Andrade, Cortez McBerry, Irini Sereti and Alan Sher
    J Immunol January 15, 2014, 192 (2) 676-682; DOI: https://doi.org/10.4049/jimmunol.1301004
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    Regulatory T Cells Shape the Resident Memory T Cell Response to Virus Infection in the Tissues
    Jessica B. Graham, Andreia Da Costa and Jennifer M. Lund
    J Immunol January 15, 2014, 192 (2) 683-690; DOI: https://doi.org/10.4049/jimmunol.1202153
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    IL-27, a Cytokine, and IFN-λ1, a Type III IFN, Are Coordinated To Regulate Virus Replication through Type I IFN
    Yanhua Cao, Rui Zhang, Wei Zhang, Chengliang Zhu, Yi Yu, Yu Song, Qing Wang, Lan Bai, Yingle Liu, Kailang Wu and Jianguo Wu
    J Immunol January 15, 2014, 192 (2) 691-703; DOI: https://doi.org/10.4049/jimmunol.1300252
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    IL-17A Produced by Neutrophils Protects against Pneumonic Plague through Orchestrating IFN-γ–Activated Macrophage Programming
    Yujing Bi, Jiyuan Zhou, Hui Yang, Xiao Wang, Xuecan Zhang, Qiong Wang, Xiaohong Wu, Yanping Han, Yajun Song, Yafang Tan, Zongmin Du, Huiying Yang, Dongsheng Zhou, Yujun Cui, Lei Zhou, Yanfeng Yan, Pingping Zhang, Zhaobiao Guo, Xiaoyi Wang, Guangwei Liu and Ruifu Yang
    J Immunol January 15, 2014, 192 (2) 704-713; DOI: https://doi.org/10.4049/jimmunol.1301687

INNATE IMMUNITY AND INFLAMMATION

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    TNFR-Associated Factor 6 and TGF-β–Activated Kinase 1 Control Signals for a Senescence Response by an Endosomal NK Cell Receptor
    Sumati Rajagopalan, Elizabeth C. Lee, Matthew L. DuPrie and Eric O. Long
    J Immunol January 15, 2014, 192 (2) 714-721; DOI: https://doi.org/10.4049/jimmunol.1302384
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    Smooth Muscle Cells Relay Acute Pulmonary Inflammation via Distinct ADAM17/ErbB Axes
    Daniela Dreymueller, Christian Martin, Julian Schumacher, Esther Groth, Julia Katharina Boehm, Lucy Kathleen Reiss, Stefan Uhlig and Andreas Ludwig
    J Immunol January 15, 2014, 192 (2) 722-731; DOI: https://doi.org/10.4049/jimmunol.1302496
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    Killer Ig-like Receptor 2DL4 Does Not Mediate NK Cell IFN-γ Responses to Soluble HLA-G Preparations
    Michael E. L. Le Page, Jodie P. Goodridge, Elisabeth John, Frank T. Christiansen and Campbell S. Witt
    J Immunol January 15, 2014, 192 (2) 732-740; DOI: https://doi.org/10.4049/jimmunol.1301748
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    ADAM17-Mediated Shedding of FcγRIIIA on Human NK Cells: Identification of the Cleavage Site and Relationship with Activation
    Laurie Lajoie, Nicolas Congy-Jolivet, Armelle Bolzec, Valérie Gouilleux-Gruart, Elodie Sicard, Hsueh Cheng Sung, Frank Peiretti, Thierry Moreau, Henri Vié, Béatrice Clémenceau and Gilles Thibault
    J Immunol January 15, 2014, 192 (2) 741-751; DOI: https://doi.org/10.4049/jimmunol.1301024
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    Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s Act on Distinct Phospholipid Pools in Zymosan-Stimulated Mouse Peritoneal Macrophages
    Luis Gil-de-Gómez, Alma M. Astudillo, Carlos Guijas, Victoria Magrioti, George Kokotos, María A. Balboa and Jesús Balsinde
    J Immunol January 15, 2014, 192 (2) 752-762; DOI: https://doi.org/10.4049/jimmunol.1302267
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    Arsenic Trioxide and Other Arsenical Compounds Inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 Inflammasomes
    Nolan K. Maier, Devorah Crown, Jie Liu, Stephen H. Leppla and Mahtab Moayeri
    J Immunol January 15, 2014, 192 (2) 763-770; DOI: https://doi.org/10.4049/jimmunol.1301434

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Guanylate Binding Protein 1–Mediated Interaction of T Cell Antigen Receptor Signaling with the Cytoskeleton
    Florian Forster, Wolfgang Paster, Verena Supper, Philipp Schatzlmaier, Stefan Sunzenauer, Nicole Ostler, Anna Saliba, Paul Eckerstorfer, Nathalie Britzen-Laurent, Gerhard Schütz, Johannes A. Schmid, Gerhard J. Zlabinger, Elisabeth Naschberger, Michael Stürzl and Hannes Stockinger
    J Immunol January 15, 2014, 192 (2) 771-781; DOI: https://doi.org/10.4049/jimmunol.1300377
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    T Cell Ig and Mucin Domain–Containing Protein 3 Is Recruited to the Immune Synapse, Disrupts Stable Synapse Formation, and Associates with Receptor Phosphatases
    Kiera L. Clayton, Matthew S. Haaland, Matthew B. Douglas-Vail, Shariq Mujib, Glen M. Chew, Lishomwa C. Ndhlovu and Mario A. Ostrowski
    J Immunol January 15, 2014, 192 (2) 782-791; DOI: https://doi.org/10.4049/jimmunol.1302663
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    Polymorphisms and Interspecies Differences of the Activating and Inhibitory FcγRII of Macaca nemestrina Influence the Binding of Human IgG Subclasses
    Halina M. Trist, Peck Szee Tan, Bruce D. Wines, Paul A. Ramsland, Eva Orlowski, Janine Stubbs, Elizabeth E. Gardiner, Geoffrey A. Pietersz, Stephen J. Kent, Ivan Stratov, Dennis R. Burton and P. Mark Hogarth
    J Immunol January 15, 2014, 192 (2) 792-803; DOI: https://doi.org/10.4049/jimmunol.1301554

MUCOSAL IMMUNOLOGY

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    Oral Escherichia coli Colonization Factor Antigen I Fimbriae Ameliorate Arthritis via IL-35, Not IL-27
    Irina Kochetkova, Theresa Thornburg, Gayle Callis, Kathryn Holderness, Massimo Maddaloni and David W. Pascual
    J Immunol January 15, 2014, 192 (2) 804-816; DOI: https://doi.org/10.4049/jimmunol.1302018

TRANSPLANTATION

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    CCL-21 Conditioned Regulatory T Cells Induce Allotolerance through Enhanced Homing to Lymphoid Tissue
    Sunil K. Chauhan, Daniel R. Saban, Thomas H. Dohlman and Reza Dana
    J Immunol January 15, 2014, 192 (2) 817-823; DOI: https://doi.org/10.4049/jimmunol.1203469

TUMOR IMMUNOLOGY

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    Membrane Transfer from Tumor Cells Overcomes Deficient Phagocytic Ability of Plasmacytoid Dendritic Cells for the Acquisition and Presentation of Tumor Antigens
    Irene Bonaccorsi, Barbara Morandi, Olga Antsiferova, Gregorio Costa, Daniela Oliveri, Romana Conte, Gaetana Pezzino, Giovanna Vermiglio, Giuseppe Pio Anastasi, Giuseppe Navarra, Christian Münz, Emma Di Carlo, Maria Cristina Mingari and Guido Ferlazzo
    J Immunol January 15, 2014, 192 (2) 824-832; DOI: https://doi.org/10.4049/jimmunol.1301039
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The Journal of Immunology: 192 (2)
The Journal of Immunology
Vol. 192, Issue 2
15 Jan 2014
  • Table of Contents
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  • IN THIS ISSUE
  • CUTTING EDGE
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNE SYSTEM DEVELOPMENT
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • MUCOSAL IMMUNOLOGY
  • TRANSPLANTATION
  • TUMOR IMMUNOLOGY
  • Highlights
  • Most Cited
  • Most Read
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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