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The Journal of Immunology

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Table of Contents

June 1, 2014; Volume 192,Issue 11

IN THIS ISSUE

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    In This Issue

    KIR-bing High Infant Birth Weight See article p. 5069

    B-1 Cells Become B-ALL See article p. 5171

    Chemokine Calls B Cells See article p. 5273

    BET-ting Basophils See article p. 5314

    Antagonizing IL-27 See article p. 5382

    Nucleic Acids Aid Protease Activity See article p. 5390

    IFN-γ Purges Pox See article p. 5415

    J Immunol June 1, 2014, 192 (11) 4939-4940; DOI: https://doi.org/10.4049/jimmunol.1490018

LETTERS TO THE EDITOR

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    Comment on “Flagellin Induces Antibody Responses through a TLR5- and Inflammasome-Independent Pathway”
    Janardan P. Pandey
    J Immunol June 1, 2014, 192 (11) 4941; DOI: https://doi.org/10.4049/jimmunol.1400524
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    Response to Comment on “Flagellin Induces Antibody Responses through a TLR5- and Inflammasome-Independent Pathway”
    Americo H. Lopez-Yglesias, Chun-Chi Lu and Kelly D. Smith
    J Immunol June 1, 2014, 192 (11) 4941-4942; DOI: https://doi.org/10.4049/jimmunol.1400685

PILLARS OF IMMUNOLOGY

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    Clonal Origins of the Hematopoietic System: The Single Most Elegant Experiment
    Irving L. Weissman
    J Immunol June 1, 2014, 192 (11) 4943-4944; DOI: https://doi.org/10.4049/jimmunol.1400902
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    Pillars Article: Cytological Demonstration of the Clonal Nature of Spleen Colonies Derived from Transplanted Mouse Marrow Cells. Nature. 1963. 197:452-454
    A. J. Becker, E. A. McCulloch and J. E. Till
    J Immunol June 1, 2014, 192 (11) 4945-4947;

BRIEF REVIEWS

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    Regulatory T Cells: New Keys for Further Unlocking the Enigma of Fetal Tolerance and Pregnancy Complications
    Tony T. Jiang, Vandana Chaturvedi, James M. Ertelt, Jeremy M. Kinder, Dayna R. Clark, Amy M. Valent, Lijun Xin and Sing Sing Way
    J Immunol June 1, 2014, 192 (11) 4949-4956; DOI: https://doi.org/10.4049/jimmunol.1400498

ANTIGEN RECOGNITION AND RESPONSES

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    Endoplasmic Reticulum Targeting Alters Regulation of Expression and Antigen Presentation of Proinsulin
    Hsiang-Ting Hsu, Linda Janßen, Myriam Lawand, Jessica Kim, Alicia Perez-Arroyo, Slobodan Culina, Abdel Gdoura, Anne Burgevin, Delphine Cumenal, Yousra Fourneau, Anna Moser, Roland Kratzer, F. Susan Wong, Sebastian Springer and Peter van Endert
    J Immunol June 1, 2014, 192 (11) 4957-4966; DOI: https://doi.org/10.4049/jimmunol.1300631
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    Distinct Assembly Profiles of HLA-B Molecules
    Syed Monem Rizvi, Nasir Salam, Jie Geng, Ying Qi, Jay H. Bream, Priya Duggal, Shehnaz K. Hussain, Jeremy Martinson, Steven M. Wolinsky, Mary Carrington and Malini Raghavan
    J Immunol June 1, 2014, 192 (11) 4967-4976; DOI: https://doi.org/10.4049/jimmunol.1301670
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    TLR3 Activation Augments Matrix Metalloproteinase Production through Reactive Nitrogen Species Generation in Human Lung Fibroblasts
    Tomohiro Ichikawa, Hisatoshi Sugiura, Akira Koarai, Yoshiaki Minakata, Takashi Kikuchi, Yukiko Morishita, Asako Oka, Kuninobu Kanai, Hiroki Kawabata, Masataka Hiramatsu, Keiichiro Akamatsu, Tsunahiko Hirano, Masanori Nakanishi, Kazuto Matsunaga, Nobuyuki Yamamoto and Masakazu Ichinose
    J Immunol June 1, 2014, 192 (11) 4977-4988; DOI: https://doi.org/10.4049/jimmunol.1302919
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    NADPH Oxidase Modifies Patterns of MHC Class II–Restricted Epitopic Repertoires through Redox Control of Antigen Processing
    Euan R. O. Allan, Pankaj Tailor, Dale R. Balce, Payman Pirzadeh, Neil T. McKenna, Bernard Renaux, Amy L. Warren, Frank R. Jirik and Robin M. Yates
    J Immunol June 1, 2014, 192 (11) 4989-5001; DOI: https://doi.org/10.4049/jimmunol.1302896
  • Open Access
    Steady-State Antigen Scavenging, Cross-Presentation, and CD8+ T Cell Priming: A New Role for Lymphatic Endothelial Cells

    Author Choice Article

    Sachiko Hirosue, Efthymia Vokali, Vidya R. Raghavan, Marcela Rincon-Restrepo, Amanda W. Lund, Patricia Corthésy-Henrioud, Francesca Capotosti, Cornelia Halin Winter, Stéphanie Hugues and Melody A. Swartz
    J Immunol June 1, 2014, 192 (11) 5002-5011; DOI: https://doi.org/10.4049/jimmunol.1302492

AUTOIMMUNITY

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    Ezh2 Regulates Transcriptional and Posttranslational Expression of T-bet and Promotes Th1 Cell Responses Mediating Aplastic Anemia in Mice
    Qing Tong, Shan He, Fang Xie, Kazuhiro Mochizuki, Yongnian Liu, Izumi Mochizuki, Lijun Meng, Hongxing Sun, Yanyun Zhang, Yajun Guo, Elizabeth Hexner and Yi Zhang
    J Immunol June 1, 2014, 192 (11) 5012-5022; DOI: https://doi.org/10.4049/jimmunol.1302943
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    Transient Systemic Inflammation Does Not Alter the Induction of Tolerance to Gastric Autoantigens by Migratory Dendritic Cells
    Dorothée Bourges, Ellen M. Ross, Stacey Allen, Simon Read, Fiona J. Houghton, Sammy Bedoui, Louis Boon, Paul A. Gleeson and Ian R. van Driel
    J Immunol June 1, 2014, 192 (11) 5023-5030; DOI: https://doi.org/10.4049/jimmunol.1303429
  • Open Access
    Therapeutic Effect of IVIG on Inflammatory Arthritis in Mice Is Dependent on the Fc Portion and Independent of Sialylation or Basophils

    Author Choice Article

    Ian K. Campbell, Sylvia Miescher, Donald R. Branch, Patrick J. Mott, Alan H. Lazarus, Dongji Han, Eugene Maraskovsky, Adrian W. Zuercher, Anton Neschadim, Danila Leontyev, Brent S. McKenzie and Fabian Käsermann
    J Immunol June 1, 2014, 192 (11) 5031-5038; DOI: https://doi.org/10.4049/jimmunol.1301611

CLINICAL AND HUMAN IMMUNOLOGY

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    Recognition of Distinct Cross-Reactive Virus-Specific CD8+ T Cells Reveals a Unique TCR Signature in a Clinical Setting
    Thi H. O. Nguyen, Louise C. Rowntree, Daniel G. Pellicci, Nicola L. Bird, Andreas Handel, Lars Kjer-Nielsen, Katherine Kedzierska, Tom C. Kotsimbos and Nicole A. Mifsud
    J Immunol June 1, 2014, 192 (11) 5039-5049; DOI: https://doi.org/10.4049/jimmunol.1303147
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    Human Lymphoid Development in the Absence of Common γ-Chain Receptor Signaling
    Lisa A. Kohn, Christopher S. Seet, Jessica Scholes, Felicia Codrea, Rebecca Chan, Sania Zaidi-Merchant, Yuhua Zhu, Satiro De Oliveira, Neena Kapoor, Ami Shah, Hisham Abdel-Azim, Donald B. Kohn and Gay M. Crooks
    J Immunol June 1, 2014, 192 (11) 5050-5058; DOI: https://doi.org/10.4049/jimmunol.1303496
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    Role of Leukotriene A4 Hydrolase Aminopeptidase in the Pathogenesis of Emphysema
    Mikell Paige, Kan Wang, Marie Burdick, Sunhye Park, Josiah Cha, Erin Jeffery, Nicholas Sherman and Y. Michael Shim
    J Immunol June 1, 2014, 192 (11) 5059-5068; DOI: https://doi.org/10.4049/jimmunol.1400452
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    Maternal KIR in Combination with Paternal HLA-C2 Regulate Human Birth Weight
    Susan E. Hiby, Richard Apps, Olympe Chazara, Lydia E. Farrell, Per Magnus, Lill Trogstad, Håkon K. Gjessing, Mary Carrington and Ashley Moffett
    J Immunol June 1, 2014, 192 (11) 5069-5073; DOI: https://doi.org/10.4049/jimmunol.1400577
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    Impact of Asymptomatic Herpes Simplex Virus Type 2 Infection on Mucosal Homing and Immune Cell Subsets in the Blood and Female Genital Tract
    Brett Shannon, Tae Joon Yi, Jamie Thomas-Pavanel, Lisungu Chieza, Praseedha Janakiram, Megan Saunders, Wangari Tharao, Sanja Huibner, Robert Remis, Anu Rebbapragada and Rupert Kaul
    J Immunol June 1, 2014, 192 (11) 5074-5082; DOI: https://doi.org/10.4049/jimmunol.1302916

IMMUNE REGULATION

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    M-CSF Inhibits Anti–HIV-1 Activity of IL-32, but They Enhance M2-like Phenotypes of Macrophages
    Abu Osman, Farzana Bhuyan, Michihiro Hashimoto, Hesham Nasser, Takaaki Maekawa and Shinya Suzu
    J Immunol June 1, 2014, 192 (11) 5083-5089; DOI: https://doi.org/10.4049/jimmunol.1302732
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    Soluble HLA-I/Peptide Monomers Mediate Antigen-Specific CD8 T Cell Activation through Passive Peptide Exchange with Cell-Bound HLA-I Molecules
    Mathilde Allard, Romain Oger, Houssem Benlalam, Laetitia Florenceau, Klara Echasserieau, Karine Bernardeau, Nathalie Labarrière, François Lang and Nadine Gervois
    J Immunol June 1, 2014, 192 (11) 5090-5097; DOI: https://doi.org/10.4049/jimmunol.1303226
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    All-trans Retinoic Acid Induces Arginase-1 and Inducible Nitric Oxide Synthase–Producing Dendritic Cells with T Cell Inhibitory Function
    Sumantha Bhatt, Jie Qin, Carole Bennett, Shiguang Qian, John J. Fung, Thomas A. Hamilton and Lina Lu
    J Immunol June 1, 2014, 192 (11) 5098-5108; DOI: https://doi.org/10.4049/jimmunol.1303073
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    An Increase in Tolerogenic Dendritic Cell and Natural Regulatory T Cell Numbers during Experimental Autoimmune Encephalomyelitis in Rras−/− Mice Results in Attenuated Disease
    Avijit Ray, Sreemanti Basu, Nichole M. Miller, Andrew M. Chan and Bonnie N. Dittel
    J Immunol June 1, 2014, 192 (11) 5109-5117; DOI: https://doi.org/10.4049/jimmunol.1302254
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    Ikaros Imposes a Barrier to CD8+ T Cell Differentiation by Restricting Autocrine IL-2 Production
    Shaun O’Brien, Rajan M. Thomas, Gerald B. Wertheim, Fuqin Zhang, Hao Shen and Andrew D. Wells
    J Immunol June 1, 2014, 192 (11) 5118-5129; DOI: https://doi.org/10.4049/jimmunol.1301992
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    Calpain-1 Contributes to IgE-Mediated Mast Cell Activation
    Zhengli Wu, Xiaochun Chen, Fang Liu, Wei Chen, Ping Wu, Adam J. Wieschhaus, Athar H. Chishti, Paul A. Roche, Wei-Min Chen and Tong-Jun Lin
    J Immunol June 1, 2014, 192 (11) 5130-5139; DOI: https://doi.org/10.4049/jimmunol.1301677
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    The Number of Responding CD4 T Cells and the Dose of Antigen Conjointly Determine the Th1/Th2 Phenotype by Modulating B7/CD28 Interactions
    Christopher D. Rudulier, K. Kai McKinstry, Ghassan A. Al-Yassin, David R. Kroeger and Peter A. Bretscher
    J Immunol June 1, 2014, 192 (11) 5140-5150; DOI: https://doi.org/10.4049/jimmunol.1301691

IMMUNE SYSTEM DEVELOPMENT

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    Overlapping and Asymmetric Functions of TCR Signaling during Thymic Selection of CD4 and CD8 Lineages
    Charles Sinclair and Benedict Seddon
    J Immunol June 1, 2014, 192 (11) 5151-5159; DOI: https://doi.org/10.4049/jimmunol.1303085
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    CD4+ T Cells from Human Neonates and Infants Are Poised Spontaneously To Run a Nonclassical IL-4 Program
    Katrin Hebel, Soenke Weinert, Benno Kuropka, Julienne Knolle, Bernhard Kosak, Gerhard Jorch, Christoph Arens, Eberhard Krause, Ruediger C. Braun-Dullaeus and Monika C. Brunner-Weinzierl
    J Immunol June 1, 2014, 192 (11) 5160-5170; DOI: https://doi.org/10.4049/jimmunol.1302539
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    Murine B-1 B Cell Progenitors Initiate B-Acute Lymphoblastic Leukemia with Features of High-Risk Disease
    Encarnacion Montecino-Rodriguez, Katy Li, Michael Fice and Kenneth Dorshkind
    J Immunol June 1, 2014, 192 (11) 5171-5178; DOI: https://doi.org/10.4049/jimmunol.1303170

IMMUNOGENETICS

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    Through an ITIM-Independent Mechanism the FcγRIIB Blocks B Cell Activation by Disrupting the Colocalized Microclustering of the B Cell Receptor and CD19
    Liling Xu, Gen Li, Jing Wang, Yilin Fan, Zhengpeng Wan, Shaosen Zhang, Samina Shaheen, Jing Li, Li Wang, Cai Yue, Yan Zhao, Fei Wang, Joseph Brzostowski, Ying-Hua Chen, Wenjie Zheng and Wanli Liu
    J Immunol June 1, 2014, 192 (11) 5179-5191; DOI: https://doi.org/10.4049/jimmunol.1400101

IMMUNOTHERAPY AND VACCINES

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    IFN-γ–Producing CD4+ T Cells Promote Generation of Protective Germinal Center–Derived IgM+ B Cell Memory against Salmonella Typhi
    Christian Perez-Shibayama, Cristina Gil-Cruz, Rodolfo Pastelin-Palacios, Luisa Cervantes-Barragan, Emiliano Hisaki, Qian Chai, Lucas Onder, Elke Scandella, Tommy Regen, Ari Waisman, Armando Isibasi, Constantino Lopez-Macias and Burkhard Ludewig
    J Immunol June 1, 2014, 192 (11) 5192-5200; DOI: https://doi.org/10.4049/jimmunol.1302526
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    Increased Immunoaccessibility of MOMP Epitopes in a Vaccine Formulated with Amphipols May Account for the Very Robust Protection Elicited against a Vaginal Challenge with Chlamydia muridarum
    Delia F. Tifrea, Sukumar Pal, Jean-Luc Popot, Melanie J. Cocco and Luis M. de la Maza
    J Immunol June 1, 2014, 192 (11) 5201-5213; DOI: https://doi.org/10.4049/jimmunol.1303392
  • Open Access
    Longitudinal Requirement for CD4+ T Cell Help for Adenovirus Vector–Elicited CD8+ T Cell Responses

    Author Choice Article

    Nicholas M. Provine, Rafael A. Larocca, Pablo Penaloza-MacMaster, Erica N. Borducchi, Anna McNally, Lily R. Parenteau, David R. Kaufman and Dan H. Barouch
    J Immunol June 1, 2014, 192 (11) 5214-5225; DOI: https://doi.org/10.4049/jimmunol.1302806

INFECTIOUS DISEASE AND HOST RESPONSE

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    Cigarette Smoke Exposure Exacerbates Lung Inflammation and Compromises Immunity to Bacterial Infection
    Amit A. Lugade, Paul N. Bogner, Thomas H. Thatcher, Patricia J. Sime, Richard P. Phipps and Yasmin Thanavala
    J Immunol June 1, 2014, 192 (11) 5226-5235; DOI: https://doi.org/10.4049/jimmunol.1302584
  • Open Access
    Kinetics of B Cell Responses to Plasmodium falciparum Erythrocyte Membrane Protein 1 in Ghanaian Women Naturally Exposed to Malaria Parasites

    Author Choice Article

    Paulina Ampomah, Liz Stevenson, Michael F. Ofori, Lea Barfod and Lars Hviid
    J Immunol June 1, 2014, 192 (11) 5236-5244; DOI: https://doi.org/10.4049/jimmunol.1400325
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    Structural and Functional Correlates of Enhanced Antiviral Immunity Generated by Heteroclitic CD8 T Cell Epitopes
    Jonathan A. Trujillo, Stephanie Gras, Kelly-Anne Twist, Nathan P. Croft, Rudragouda Channappanavar, Jamie Rossjohn, Anthony W. Purcell and Stanley Perlman
    J Immunol June 1, 2014, 192 (11) 5245-5256; DOI: https://doi.org/10.4049/jimmunol.1400111

INNATE IMMUNITY AND INFLAMMATION

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    Leukocyte HMGB1 Is Required for Vessel Remodeling in Regenerating Muscles
    Lara Campana, Francesco Santarella, Antonio Esposito, Norma Maugeri, Elena Rigamonti, Antonella Monno, Tamara Canu, Alessandro Del Maschio, Marco E. Bianchi, Angelo A. Manfredi and Patrizia Rovere-Querini
    J Immunol June 1, 2014, 192 (11) 5257-5264; DOI: https://doi.org/10.4049/jimmunol.1300938
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    B Cells Are Not Essential for Lactobacillus-Mediated Protection against Lethal Pneumovirus Infection
    Caroline M. Percopo, Kimberly D. Dyer, Katia E. Garcia-Crespo, Stanislaw J. Gabryszewski, Arthur L. Shaffer III, Joseph B. Domachowske and Helene F. Rosenberg
    J Immunol June 1, 2014, 192 (11) 5265-5272; DOI: https://doi.org/10.4049/jimmunol.1400087
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    MIF Promotes B Cell Chemotaxis through the Receptors CXCR4 and CD74 and ZAP-70 Signaling
    Christina Klasen, Kim Ohl, Marieke Sternkopf, Idit Shachar, Corinna Schmitz, Nicole Heussen, Elias Hobeika, Ella Levit-Zerdoun, Klaus Tenbrock, Michael Reth, Jürgen Bernhagen and Omar El Bounkari
    J Immunol June 1, 2014, 192 (11) 5273-5284; DOI: https://doi.org/10.4049/jimmunol.1302209
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    Recombinant Human Hyaluronidase PH20 Does Not Stimulate an Acute Inflammatory Response and Inhibits Lipopolysaccharide-Induced Neutrophil Recruitment in the Air Pouch Model of Inflammation
    Zhongdong Huang, Chunmei Zhao, Yanling Chen, Jessica A. Cowell, Ge Wei, Anne Kultti, Lei Huang, Curtis B. Thompson, Sanna Rosengren, Gregory I. Frost and H. Michael Shepard
    J Immunol June 1, 2014, 192 (11) 5285-5295; DOI: https://doi.org/10.4049/jimmunol.1303060
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    Endothelial PINK1 Mediates the Protective Effects of NLRP3 Deficiency during Lethal Oxidant Injury
    Yi Zhang, Maor Sauler, Amanda S. Shinn, Huan Gong, Maria Haslip, Peiying Shan, Praveen Mannam and Patty J. Lee
    J Immunol June 1, 2014, 192 (11) 5296-5304; DOI: https://doi.org/10.4049/jimmunol.1400653
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    Cross-Desensitization of CCR1, but Not CCR2, following Activation of the Formyl Peptide Receptor FPR1
    Filip Bednar, Changcheng Song, Giuseppe Bardi, William Cornwell and Thomas J. Rogers
    J Immunol June 1, 2014, 192 (11) 5305-5313; DOI: https://doi.org/10.4049/jimmunol.1302983
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    NADPH Oxidase–Independent Formation of Extracellular DNA Traps by Basophils
    Mahbubul Morshed, Ruslan Hlushchuk, Dagmar Simon, Andrew F. Walls, Kazushige Obata-Ninomiya, Hajime Karasuyama, Valentin Djonov, Alexander Eggel, Thomas Kaufmann, Hans-Uwe Simon and Shida Yousefi
    J Immunol June 1, 2014, 192 (11) 5314-5323; DOI: https://doi.org/10.4049/jimmunol.1303418
  • Open Access
    Double Blockade of CD14 and Complement C5 Abolishes the Cytokine Storm and Improves Morbidity and Survival in Polymicrobial Sepsis in Mice

    Author Choice Article

    Markus Huber-Lang, Andreas Barratt-Due, Søren E. Pischke, Øystein Sandanger, Per H. Nilsson, Miles A. Nunn, Stephanie Denk, Wilhelm Gaus, Terje Espevik and Tom E. Mollnes
    J Immunol June 1, 2014, 192 (11) 5324-5331; DOI: https://doi.org/10.4049/jimmunol.1400341
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    A Polysaccharide Virulence Factor of a Human Fungal Pathogen Induces Neutrophil Apoptosis via NK Cells
    Pauline Robinet, Florence Baychelier, Thierry Fontaine, Capucine Picard, Patrice Debré, Vincent Vieillard, Jean-Paul Latgé and Carole Elbim
    J Immunol June 1, 2014, 192 (11) 5332-5342; DOI: https://doi.org/10.4049/jimmunol.1303180
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    Myeloid PTEN Deficiency Protects Livers from Ischemia Reperfusion Injury by Facilitating M2 Macrophage Differentiation
    Shi Yue, Jianhua Rao, Jianjun Zhu, Ronald W. Busuttil, Jerzy W. Kupiec-Weglinski, Ling Lu, Xuehao Wang and Yuan Zhai
    J Immunol June 1, 2014, 192 (11) 5343-5353; DOI: https://doi.org/10.4049/jimmunol.1400280
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    Acute-Phase Protein α1-Antitrypsin—A Novel Regulator of Angiopoietin-like Protein 4 Transcription and Secretion
    Eileen Frenzel, Sabine Wrenger, Stephan Immenschuh, Rembert Koczulla, Ravi Mahadeva, H. Joachim Deeg, Charles A. Dinarello, Tobias Welte, A. Mario Q. Marcondes and Sabina Janciauskiene
    J Immunol June 1, 2014, 192 (11) 5354-5362; DOI: https://doi.org/10.4049/jimmunol.1400378
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    Citrullination Alters Immunomodulatory Function of LL-37 Essential for Prevention of Endotoxin-Induced Sepsis
    Joanna Koziel, Danuta Bryzek, Aneta Sroka, Katarzyna Maresz, Izabela Glowczyk, Ewa Bielecka, Tomasz Kantyka, Krzysztof Pyrć, Pavel Svoboda, Jan Pohl and Jan Potempa
    J Immunol June 1, 2014, 192 (11) 5363-5372; DOI: https://doi.org/10.4049/jimmunol.1303062
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    TLR Costimulation Causes Oxidative Stress with Unbalance of Proinflammatory and Anti-Inflammatory Cytokine Production
    Rosa Lavieri, Patrizia Piccioli, Sonia Carta, Laura Delfino, Patrizia Castellani and Anna Rubartelli
    J Immunol June 1, 2014, 192 (11) 5373-5381; DOI: https://doi.org/10.4049/jimmunol.1303480

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    A Soluble Form of IL-27Rα Is a Natural IL-27 Antagonist
    Céline Dietrich, Sophie Candon, Frank M. Ruemmele and Odile Devergne
    J Immunol June 1, 2014, 192 (11) 5382-5389; DOI: https://doi.org/10.4049/jimmunol.1303435
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    Leukocyte Protease Binding to Nucleic Acids Promotes Nuclear Localization and Cleavage of Nucleic Acid Binding Proteins
    Marshall P. Thomas, Jennifer Whangbo, Geoffrey McCrossan, Aaron J. Deutsch, Kimberly Martinod, Michael Walch and Judy Lieberman
    J Immunol June 1, 2014, 192 (11) 5390-5397; DOI: https://doi.org/10.4049/jimmunol.1303296
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    Adjustable Locks and Flexible Keys: Plasticity of Epitope–Paratope Interactions in Germline Antibodies
    Tarique Khan and Dinakar M. Salunke
    J Immunol June 1, 2014, 192 (11) 5398-5405; DOI: https://doi.org/10.4049/jimmunol.1302143
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    The Ligand-Binding Domain of Siglec-G Is Crucial for Its Selective Inhibitory Function on B1 Cells
    Stefan Hutzler, Lamia Özgör, Yuko Naito-Matsui, Kathrin Kläsener, Thomas H. Winkler, Michael Reth and Lars Nitschke
    J Immunol June 1, 2014, 192 (11) 5406-5414; DOI: https://doi.org/10.4049/jimmunol.1302875

MUCOSAL IMMUNOLOGY

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    CD8 T Cells Use IFN-γ To Protect against the Lethal Effects of a Respiratory Poxvirus Infection
    John Goulding, Georges Abboud, Vikas Tahiliani, Pritesh Desai, Tarun E. Hutchinson and Shahram Salek-Ardakani
    J Immunol June 1, 2014, 192 (11) 5415-5425; DOI: https://doi.org/10.4049/jimmunol.1400256

TRANSPLANTATION

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    Cross-Dressing by Donor Dendritic Cells after Allogeneic Bone Marrow Transplantation Contributes to Formation of the Immunological Synapse and Maximizes Responses to Indirectly Presented Antigen
    Kate A. Markey, Motoko Koyama, Kate H. Gartlan, Lucie Leveque, Rachel D. Kuns, Katie E. Lineburg, Bianca E. Teal, Kelli P. A. MacDonald and Geoffrey R. Hill
    J Immunol June 1, 2014, 192 (11) 5426-5433; DOI: https://doi.org/10.4049/jimmunol.1302490

TUMOR IMMUNOLOGY

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    Multiple Roles of Perforin in Hampering ERBB-2 (Her-2/neu) Carcinogenesis in Transgenic Male Mice
    Marco Macagno, Silvio Bandini, Lorenzo Stramucci, Elena Quaglino, Laura Conti, Elisa Balmas, Mark J. Smyth, Pier-Luigi Lollini, Piero Musiani, Guido Forni, Manuela Iezzi and Federica Cavallo
    J Immunol June 1, 2014, 192 (11) 5434-5441; DOI: https://doi.org/10.4049/jimmunol.1301248
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The Journal of Immunology: 192 (11)
The Journal of Immunology
Vol. 192, Issue 11
1 Jun 2014
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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