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The Journal of Immunology

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Table of Contents

October 15, 2013; Volume 191,Issue 8

IN THIS ISSUE

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    In This Issue

    Teaching an Old Peptidase New Tricks See article p. 4020

    The Price of Internalizing Inhibition See article p. 4130

    mAbs To Manage Metastasis See article p. 4165

    Complementing Infection See article p. 4235

    Breaking the Epithelial Barrier See article p. 4246

    Tcf7 Regulates ILC Subsets See article p. 4383

    J Immunol October 15, 2013, 191 (8) 3971-3972; DOI: https://doi.org/10.4049/jimmunol.1390051

BRIEF REVIEWS

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    TGF-β: Guardian of T Cell Function
    Soyoung A. Oh and Ming O. Li
    J Immunol October 15, 2013, 191 (8) 3973-3979; DOI: https://doi.org/10.4049/jimmunol.1301843

CUTTING EDGE

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    Cutting Edge: NK Cell Licensing Modulates Adhesion to Target Cells
    L. Michael Thomas, Mary E. Peterson and Eric O. Long
    J Immunol October 15, 2013, 191 (8) 3981-3985; DOI: https://doi.org/10.4049/jimmunol.1301159
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    Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein
    Manira Rayamajhi, Daniel E. Zak, Joseph Chavarria-Smith, Russell E. Vance and Edward A. Miao
    J Immunol October 15, 2013, 191 (8) 3986-3989; DOI: https://doi.org/10.4049/jimmunol.1301549
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    Cutting Edge: CD4 T Cells Reactive to an Islet Amyloid Polypeptide Peptide Accumulate in the Pancreas and Contribute to Disease Pathogenesis in Nonobese Diabetic Mice
    Rocky L. Baker, Thomas Delong, Gene Barbour, Brenda Bradley, Maki Nakayama and Kathryn Haskins
    J Immunol October 15, 2013, 191 (8) 3990-3994; DOI: https://doi.org/10.4049/jimmunol.1301480
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    Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome
    Teresa Fernandes-Alnemri, Seokwon Kang, Connor Anderson, Junji Sagara, Katherine A. Fitzgerald and Emad S. Alnemri
    J Immunol October 15, 2013, 191 (8) 3995-3999; DOI: https://doi.org/10.4049/jimmunol.1301681

ALLERGY AND OTHER HYPERSENSITIVITIES

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    Disruption of the Complement Anaphylatoxin Receptor C5L2 Exacerbates Inflammation in Allergic Contact Dermatitis
    Ruobing Wang, Bao Lu, Craig Gerard and Norma P. Gerard
    J Immunol October 15, 2013, 191 (8) 4001-4009; DOI: https://doi.org/10.4049/jimmunol.1301626

ANTIGEN RECOGNITION AND RESPONSES

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    Defining CD8+ T Cell Determinants during Human Viral Infection in Populations of Asian Ethnicity
    Laura Rivino, Anthony T. Tan, Adeline Chia, Emmanuelle A. P. Kumaran, Gijsbert M. Grotenbreg, Paul A. MacAry and Antonio Bertoletti
    J Immunol October 15, 2013, 191 (8) 4010-4019; DOI: https://doi.org/10.4049/jimmunol.1301507
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    New Role of Signal Peptide Peptidase To Liberate C-Terminal Peptides for MHC Class I Presentation
    Cláudia C. Oliveira, Bianca Querido, Marjolein Sluijter, Anne F. de Groot, Reno van der Zee, Martijn J. W. E. Rabelink, Rob C. Hoeben, Ferry Ossendorp, Sjoerd H. van der Burg and Thorbald van Hall
    J Immunol October 15, 2013, 191 (8) 4020-4028; DOI: https://doi.org/10.4049/jimmunol.1301496

AUTOIMMUNITY

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    Ablation of Peroxiredoxin II Attenuates Experimental Colitis by Increasing FoxO1-Induced Foxp3+ Regulatory T Cells
    Hee Yeon Won, Eun Jung Jang, Kihyun Lee, Sera Oh, Hyo Kyung Kim, Hyun Ae Woo, Sang Won Kang, Dae-Yeul Yu, Sue-Goo Rhee and Eun Sook Hwang
    J Immunol October 15, 2013, 191 (8) 4029-4037; DOI: https://doi.org/10.4049/jimmunol.1203247
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    Fatal Eosinophilic Myocarditis Develops in the Absence of IFN-γ and IL-17A
    Jobert G. Barin, G. Christian Baldeviano, Monica V. Talor, Lei Wu, SuFey Ong, DeLisa Fairweather, Djahida Bedja, Natalie R. Stickel, Jillian A. Fontes, Ashley B. Cardamone, Dongfeng Zheng, Kathleen L. Gabrielson, Noel R. Rose and Daniela Čiháková
    J Immunol October 15, 2013, 191 (8) 4038-4047; DOI: https://doi.org/10.4049/jimmunol.1301282

IMMUNE REGULATION

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    Ezrin Tunes the Magnitude of Humoral Immunity
    Debasis Pore, Neetha Parameswaran, Ken Matsui, Matthew B. Stone, Ichiko Saotome, Andrea I. McClatchey, Sarah L. Veatch and Neetu Gupta
    J Immunol October 15, 2013, 191 (8) 4048-4058; DOI: https://doi.org/10.4049/jimmunol.1301315
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    Activated Platelets Enhance IL-10 Secretion and Reduce TNF-α Secretion by Monocytes
    Sif Gudbrandsdottir, Hans C. Hasselbalch and Claus H. Nielsen
    J Immunol October 15, 2013, 191 (8) 4059-4067; DOI: https://doi.org/10.4049/jimmunol.1201103
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    Heat Shock Transcription Factor 1 Is Activated as a Consequence of Lymphocyte Activation and Regulates a Major Proteostasis Network in T Cells Critical for Cell Division During Stress
    Siva K. Gandhapudi, Patience Murapa, Zachary D. Threlkeld, Martin Ward, Kevin D. Sarge, Charles Snow and Jerold G. Woodward
    J Immunol October 15, 2013, 191 (8) 4068-4079; DOI: https://doi.org/10.4049/jimmunol.1202831
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    LAT1 Is a Critical Transporter of Essential Amino Acids for Immune Reactions in Activated Human T Cells
    Keitaro Hayashi, Promsuk Jutabha, Hitoshi Endou, Hironori Sagara and Naohiko Anzai
    J Immunol October 15, 2013, 191 (8) 4080-4085; DOI: https://doi.org/10.4049/jimmunol.1300923
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    IL-21 Enhances the Activity of the TLR–MyD88–STAT3 Pathway but Not the Classical TLR–MyD88–NF-κB Pathway in Human B Cells To Boost Antibody Production
    Bi-Sheng Liu, Jeroen N. Stoop, Tom W. Huizinga and Rene E. M. Toes
    J Immunol October 15, 2013, 191 (8) 4086-4094; DOI: https://doi.org/10.4049/jimmunol.1300765
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    Cholera Toxin Directly Enhances IL-17A Production from Human CD4+ T Cells
    Hsing-Chuan Tsai and Reen Wu
    J Immunol October 15, 2013, 191 (8) 4095-4102; DOI: https://doi.org/10.4049/jimmunol.1301079
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    Both MC5r and A2Ar Are Required for Protective Regulatory Immunity in the Spleen of Post–Experimental Autoimmune Uveitis in Mice
    Darren J. Lee and Andrew W. Taylor
    J Immunol October 15, 2013, 191 (8) 4103-4111; DOI: https://doi.org/10.4049/jimmunol.1300182
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    Pneumococcal Components Induce Regulatory T Cells That Attenuate the Development of Allergic Airways Disease by Deviating and Suppressing the Immune Response to Allergen
    Alison N. Thorburn, Alexandra C. Brown, Prema M. Nair, Nina Chevalier, Paul S. Foster, Peter G. Gibson and Philip M. Hansbro
    J Immunol October 15, 2013, 191 (8) 4112-4120; DOI: https://doi.org/10.4049/jimmunol.1201232

IMMUNOTHERAPY AND VACCINES

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    Human T Cells Engineered To Express a Programmed Death 1/28 Costimulatory Retargeting Molecule Display Enhanced Antitumor Activity
    Chen Ankri, Katerina Shamalov, Miryam Horovitz-Fried, Shmuel Mauer and Cyrille J. Cohen
    J Immunol October 15, 2013, 191 (8) 4121-4129; DOI: https://doi.org/10.4049/jimmunol.1203085
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    Immunotherapy Targeting Inhibitory Fcγ Receptor IIB (CD32b) in the Mouse Is Limited by Monoclonal Antibody Consumption and Receptor Internalization
    Emily L. Williams, Alison L. Tutt, Stephen A. Beers, Ruth R. French, Claude H. T. Chan, Kerry L. Cox, Ali Roghanian, Christine A. Penfold, Cherié L. Butts, Peter Boross, J. Sjef Verbeek, Mark S. Cragg and Martin J. Glennie
    J Immunol October 15, 2013, 191 (8) 4130-4140; DOI: https://doi.org/10.4049/jimmunol.1301430
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    Inhibition of Breast Cancer Metastasis by Resveratrol-Mediated Inactivation of Tumor-Evoked Regulatory B Cells
    Catalina Lee-Chang, Monica Bodogai, Alejandro Martin-Montalvo, Katarzyna Wejksza, Mitesh Sanghvi, Ruin Moaddel, Rafael de Cabo and Arya Biragyn
    J Immunol October 15, 2013, 191 (8) 4141-4151; DOI: https://doi.org/10.4049/jimmunol.1300606
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    Adenovirus-Based Vaccine against Listeria monocytogenes: Extending the Concept of Invariant Chain Linkage
    Søren Jensen, Maria Abildgaard Steffensen, Benjamin Anderschou Holbech Jensen, Dirk Schlüter, Jan Pravsgaard Christensen and Allan Randrup Thomsen
    J Immunol October 15, 2013, 191 (8) 4152-4164; DOI: https://doi.org/10.4049/jimmunol.1301290
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    Anti-Human CD73 Monoclonal Antibody Inhibits Metastasis Formation in Human Breast Cancer by Inducing Clustering and Internalization of CD73 Expressed on the Surface of Cancer Cells
    Mikkel G. Terp, Kristina A. Olesen, Eva C. Arnspang, Rikke R. Lund, B. Christoffer Lagerholm, Henrik J. Ditzel and Rikke Leth-Larsen
    J Immunol October 15, 2013, 191 (8) 4165-4173; DOI: https://doi.org/10.4049/jimmunol.1301274
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    Agonist Anti-Human CD27 Monoclonal Antibody Induces T Cell Activation and Tumor Immunity in Human CD27–Transgenic Mice
    Li-Zhen He, Naseem Prostak, Lawrence J. Thomas, Laura Vitale, Jeffrey Weidlick, Andrea Crocker, Catherine D. Pilsmaker, Sarah M. Round, Alison Tutt, Martin J. Glennie, Henry Marsh and Tibor Keler
    J Immunol October 15, 2013, 191 (8) 4174-4183; DOI: https://doi.org/10.4049/jimmunol.1300409
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    IL-12–Based Vaccination Therapy Reverses Liver-Induced Systemic Tolerance in a Mouse Model of Hepatitis B Virus Carrier
    Zhutian Zeng, Xiaohui Kong, Fenglei Li, Haiming Wei, Rui Sun and Zhigang Tian
    J Immunol October 15, 2013, 191 (8) 4184-4193; DOI: https://doi.org/10.4049/jimmunol.1203449

INFECTIOUS DISEASE AND HOST RESPONSE

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    The Roles of IRF-3 and IRF-7 in Innate Antiviral Immunity against Dengue Virus
    Hui-Wen Chen, Kevin King, Jui Tu, Marisa Sanchez, Andrew D. Luster and Sujan Shresta
    J Immunol October 15, 2013, 191 (8) 4194-4201; DOI: https://doi.org/10.4049/jimmunol.1300799
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    Regulation of the Development of the Hepatic B Cell Compartment during Schistosoma mansoni Infection
    Keke C. Fairfax, Bart Everts, Amber M. Smith and Edward J. Pearce
    J Immunol October 15, 2013, 191 (8) 4202-4210; DOI: https://doi.org/10.4049/jimmunol.1301357
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    CD8+ Memory T Cells Appear Exhausted within Hours of Acute Virus Infection
    Martin P. Hosking, Claudia T. Flynn, Jason Botten and J. Lindsay Whitton
    J Immunol October 15, 2013, 191 (8) 4211-4222; DOI: https://doi.org/10.4049/jimmunol.1300920
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    Identifying the Initiating Events of Anti-Listeria Responses Using Mice with Conditional Loss of IFN-γ Receptor Subunit 1 (IFNGR1)
    Sang Hun Lee, Javier A. Carrero, Ravindra Uppaluri, J. Michael White, Jessica M. Archambault, Koon Siew Lai, Szeman Ruby Chan, Kathleen C. F. Sheehan, Emil R. Unanue and Robert D. Schreiber
    J Immunol October 15, 2013, 191 (8) 4223-4234; DOI: https://doi.org/10.4049/jimmunol.1300910
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    An Alternative Role of C1q in Bacterial Infections: Facilitating Streptococcus pneumoniae Adherence and Invasion of Host Cells
    Vaibhav Agarwal, Jonas Ahl, Kristian Riesbeck and Anna M. Blom
    J Immunol October 15, 2013, 191 (8) 4235-4245; DOI: https://doi.org/10.4049/jimmunol.1300279
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    HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium
    Aisha Nazli, Jessica K. Kafka, Victor H. Ferreira, Varun Anipindi, Kristen Mueller, Brendan J. Osborne, Sara Dizzell, Sarah Chauvin, M. Firoz Mian, Michel Ouellet, Michel J. Tremblay, Karen L. Mossman, Ali A. Ashkar, Colin Kovacs, Dawn M. E. Bowdish, Denis P. Snider, Rupert Kaul and Charu Kaushic
    J Immunol October 15, 2013, 191 (8) 4246-4258; DOI: https://doi.org/10.4049/jimmunol.1301482
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    Increased Susceptibility to Pulmonary Pseudomonas Infection in Splunc1 Knockout Mice
    Yanyan Liu, Marissa E. Di, Hong Wei Chu, Xinyu Liu, Ling Wang, Sally Wenzel and Y. Peter Di
    J Immunol October 15, 2013, 191 (8) 4259-4268; DOI: https://doi.org/10.4049/jimmunol.1202340
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    CD4+ T Cell Expression of MyD88 Is Essential for Normal Resolution of Chlamydia muridarum Genital Tract Infection
    Lauren C. Frazer, Jeanne E. Sullivan, Matthew A. Zurenski, Margaret Mintus, Tammy E. Tomasak, Daniel Prantner, Uma M. Nagarajan and Toni Darville
    J Immunol October 15, 2013, 191 (8) 4269-4279; DOI: https://doi.org/10.4049/jimmunol.1301547
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    RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Is Decreased during Simian Immunodeficiency Virus–Associated Central Nervous System Disease
    Daniele C. Cary, Janice E. Clements and Andrew J. Henderson
    J Immunol October 15, 2013, 191 (8) 4280-4287; DOI: https://doi.org/10.4049/jimmunol.1300797

INNATE IMMUNITY AND INFLAMMATION

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    Maresin 1, a Proresolving Lipid Mediator Derived from Omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis
    Rodrigo Marcon, Allisson F. Bento, Rafael C. Dutra, Maira A. Bicca, Daniela F. P. Leite and João B. Calixto
    J Immunol October 15, 2013, 191 (8) 4288-4298; DOI: https://doi.org/10.4049/jimmunol.1202743
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    The p38-MSK1 Signaling Cascade Influences Cytokine Production through CREB and C/EBP Factors in Human Neutrophils
    Thomas Z. Mayer, François A. Simard, Alexandre Cloutier, Harsh Vardhan, Claire M. Dubois and Patrick P. McDonald
    J Immunol October 15, 2013, 191 (8) 4299-4307; DOI: https://doi.org/10.4049/jimmunol.1301117
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    Inflammatory Responses Induced by Lipopolysaccharide Are Amplified in Primary Human Monocytes but Suppressed in Macrophages by Complement Protein C5a
    Vernon Seow, Junxian Lim, Abishek Iyer, Jacky Y. Suen, Juliana K. Ariffin, Daniel M. Hohenhaus, Matthew J. Sweet and David P. Fairlie
    J Immunol October 15, 2013, 191 (8) 4308-4316; DOI: https://doi.org/10.4049/jimmunol.1301355
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    IL-33 Markedly Activates Murine Eosinophils by an NF-κB–Dependent Mechanism Differentially Dependent upon an IL-4–Driven Autoinflammatory Loop
    Carine Bouffi, Mark Rochman, Christopher B. Zust, Emily M. Stucke, Andrey Kartashov, Patricia C. Fulkerson, Artem Barski and Marc E. Rothenberg
    J Immunol October 15, 2013, 191 (8) 4317-4325; DOI: https://doi.org/10.4049/jimmunol.1301465
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    Conjugated Linoleic Acid Targets β2 Integrin Expression To Suppress Monocyte Adhesion
    Monica de Gaetano, Eugene Dempsey, Simone Marcone, William G. James and Orina Belton
    J Immunol October 15, 2013, 191 (8) 4326-4336; DOI: https://doi.org/10.4049/jimmunol.1300990
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    Inflammasome-Mediated Secretion of IL-1β in Human Monocytes through TLR2 Activation; Modulation by Dietary Fatty Acids
    Ryan G. Snodgrass, Shurong Huang, Il-Whan Choi, John C. Rutledge and Daniel H. Hwang
    J Immunol October 15, 2013, 191 (8) 4337-4347; DOI: https://doi.org/10.4049/jimmunol.1300298
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    IL-17 Promotes Neutrophil Entry into Tumor-Draining Lymph Nodes following Induction of Sterile Inflammation
    Craig M. Brackett, Jason B. Muhitch, Sharon S. Evans and Sandra O. Gollnick
    J Immunol October 15, 2013, 191 (8) 4348-4357; DOI: https://doi.org/10.4049/jimmunol.1103621
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    The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity
    Sangjun Park, Christine Juliana, Sujeong Hong, Pinaki Datta, Inhwa Hwang, Teresa Fernandes-Alnemri, Je-Wook Yu and Emad S. Alnemri
    J Immunol October 15, 2013, 191 (8) 4358-4366; DOI: https://doi.org/10.4049/jimmunol.1301170
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    The Complement Anaphylatoxin C5a Receptor Contributes to Obese Adipose Tissue Inflammation and Insulin Resistance
    Julia Phieler, Kyoung-Jin Chung, Antonios Chatzigeorgiou, Anne Klotzsche-von Ameln, Ruben Garcia-Martin, David Sprott, Maria Moisidou, Theodora Tzanavari, Barbara Ludwig, Elena Baraban, Monika Ehrhart-Bornstein, Stefan R. Bornstein, Hassan Mziaut, Michele Solimena, Katia P. Karalis, Matina Economopoulou, John D. Lambris and Triantafyllos Chavakis
    J Immunol October 15, 2013, 191 (8) 4367-4374; DOI: https://doi.org/10.4049/jimmunol.1300038
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    Annexin-A1 Regulates TLR-Mediated IFN-β Production through an Interaction with TANK-Binding Kinase 1
    Pradeep Bist, Shinla Shu, Huiyin Lee, Suruchi Arora, Sunitha Nair, Jyue Yuen Lim, Jivanaah Dayalan, Stephan Gasser, Subhra K. Biswas, Anna-Marie Fairhurst and Lina H. K. Lim
    J Immunol October 15, 2013, 191 (8) 4375-4382; DOI: https://doi.org/10.4049/jimmunol.1301504
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    TCF-1 Controls ILC2 and NKp46+RORγt+ Innate Lymphocyte Differentiation and Protection in Intestinal Inflammation
    Lisa A. Mielke, Joanna R. Groom, Lucille C. Rankin, Cyril Seillet, Frederick Masson, Tracy Putoczki and Gabrielle T. Belz
    J Immunol October 15, 2013, 191 (8) 4383-4391; DOI: https://doi.org/10.4049/jimmunol.1301228
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    Lithium Attenuates IFN-β Production and Antiviral Response via Inhibition of TANK-Binding Kinase 1 Kinase Activity
    Lijuan Wang, Lei Zhang, Xueying Zhao, Meng Zhang, Wei Zhao and Chengjiang Gao
    J Immunol October 15, 2013, 191 (8) 4392-4398; DOI: https://doi.org/10.4049/jimmunol.1203142

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Role of the Igh Intronic Enhancer Eμ in Clonal Selection at the Pre–B to Immature B Cell Transition
    Cheng Peng and Laurel A. Eckhardt
    J Immunol October 15, 2013, 191 (8) 4399-4411; DOI: https://doi.org/10.4049/jimmunol.1301858

MUCOSAL IMMUNOLOGY

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    Important Role for FcγRIIB on B Lymphocytes for Mucosal Antigen-Induced Tolerance and Foxp3+ Regulatory T Cells
    Jia-Bin Sun, Zou Xiang, Kenneth G. C. Smith and Jan Holmgren
    J Immunol October 15, 2013, 191 (8) 4412-4422; DOI: https://doi.org/10.4049/jimmunol.1301324
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    Pre-existing Tolerance Shapes the Outcome of Mucosal Allergen Sensitization in a Murine Model of Asthma
    Timothy J. Chapman, Jason A. Emo, Sara A. Knowlden, Fariba Rezaee and Steve N. Georas
    J Immunol October 15, 2013, 191 (8) 4423-4430; DOI: https://doi.org/10.4049/jimmunol.1300042

TRANSPLANTATION

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    Role of Complement Activation in Obliterative Bronchiolitis Post–Lung Transplantation
    Hidemi Suzuki, Mark E. Lasbury, Lin Fan, Ragini Vittal, Elizabeth A. Mickler, Heather L. Benson, Rebecca Shilling, Qiang Wu, Daniel J. Weber, Sarah R. Wagner, Melissa Lasaro, Denise Devore, Yi Wang, George E. Sandusky, Kelsey Lipking, Pankita Pandya, John Reynolds, Robert Love, Thomas Wozniak, Hongmei Gu, Krista M. Brown and David S. Wilkes
    J Immunol October 15, 2013, 191 (8) 4431-4439; DOI: https://doi.org/10.4049/jimmunol.1202242
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    Double Deficiency for RORγt and T-bet Drives Th2-Mediated Allograft Rejection in Mice
    Manije Sabet-Baktach, Elke Eggenhofer, Jordi Rovira, Philipp Renner, Margareta Lantow, Stefan A. Farkas, Muriel Malaisé, Karoline Edtinger, Zhou Shaotang, Gudrun E. Koehl, Marc H. Dahlke, Hans J. Schlitt, Edward K. Geissler and Alexander Kroemer
    J Immunol October 15, 2013, 191 (8) 4440-4446; DOI: https://doi.org/10.4049/jimmunol.1301741
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    Interruption of Dendritic Cell–Mediated TIM-4 Signaling Induces Regulatory T Cells and Promotes Skin Allograft Survival
    Melissa Y. Yeung, Martina M. McGrath, Masafumi Nakayama, Tetsunosuke Shimizu, Olaf Boenisch, Ciara N. Magee, Rozita Abdoli, Hisaya Akiba, Takuya Ueno, Laurence A. Turka and Nader Najafian
    J Immunol October 15, 2013, 191 (8) 4447-4455; DOI: https://doi.org/10.4049/jimmunol.1300992

TUMOR IMMUNOLOGY

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    Identification of the Cellular Sentinels for Native Immunogenic Heat Shock Proteins In Vivo
    Michelle Nicole Messmer, Joshua Pasmowitz, Laura Elizabeth Kropp, Simon C. Watkins and Robert Julian Binder
    J Immunol October 15, 2013, 191 (8) 4456-4465; DOI: https://doi.org/10.4049/jimmunol.1300827
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The Journal of Immunology: 191 (8)
The Journal of Immunology
Vol. 191, Issue 8
15 Oct 2013
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  • IN THIS ISSUE
  • BRIEF REVIEWS
  • CUTTING EDGE
  • ALLERGY AND OTHER HYPERSENSITIVITIES
  • ANTIGEN RECOGNITION AND RESPONSES
  • AUTOIMMUNITY
  • IMMUNE REGULATION
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • MUCOSAL IMMUNOLOGY
  • TRANSPLANTATION
  • TUMOR IMMUNOLOGY
  • Highlights
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606