About the Cover
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On the cover: Focal adhesion formation on peritoneal macrophages treated with PGE2 for 18 h. Vinculin (red) accumulates in focal adhesion plaques, and anchors filamentous actin stress fibers (green) to the cytoplasmic membrane. M. D. Díaz-Muoz, I. C. Osma-García, M. A. Íñiguez, and M. Fresno. 2013. Cyclooxygenase-2 deficiency in macrophages leads to defective p110γ PI3K signaling and impairs cell adhesion and migration. J. Immunol. 191: 395–406.