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The Journal of Immunology

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Table of Contents

July 1, 2013; Volume 191,Issue 1

EDITORIAL

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    Working To Fill the Boss’s Shoes
    Pamela J. Fink
    J Immunol July 1, 2013, 191 (1) 1-2; DOI: https://doi.org/10.4049/jimmunol.1390035

IN THIS ISSUE

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    In This Issue
    J Immunol July 1, 2013, 191 (1) 3-4; DOI: https://doi.org/10.4049/jimmunol.1390034

PILLARS OF IMMUNOLOGY

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    Genome Engineering with Cre-loxP
    Nancy Maizels
    J Immunol July 1, 2013, 191 (1) 5-6; DOI: https://doi.org/10.4049/jimmunol.1301241
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    Pillars Article: Independent Control of Immunoglobulin Switch Recombination at Individual Switch Regions Evidenced through Cre-loxP-Mediated Gene Targeting. Cell. 1993. 73: 1155-1164
    Hua Gu, Yong-Rui Zou and Klaus Rajewsky
    J Immunol July 1, 2013, 191 (1) 7-16;

BRIEF REVIEWS

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    Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells
    Srinivas Nagaraj, Je-In Youn and Dmitry I. Gabrilovich
    J Immunol July 1, 2013, 191 (1) 17-23; DOI: https://doi.org/10.4049/jimmunol.1300654

CUTTING EDGE

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    Cutting Edge: Inhaled Antigen Upregulates Retinaldehyde Dehydrogenase in Lung CD103+ but Not Plasmacytoid Dendritic Cells To Induce Foxp3 De Novo in CD4+ T Cells and Promote Airway Tolerance
    Anupriya Khare, Nandini Krishnamoorthy, Timothy B. Oriss, Mingjian Fei, Prabir Ray and Anuradha Ray
    J Immunol July 1, 2013, 191 (1) 25-29; DOI: https://doi.org/10.4049/jimmunol.1300193
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    Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human Vδ3 T Cells
    Bozgana A. Mangan, Margaret R. Dunne, Vincent P. O’Reilly, Pádraic J. Dunne, Mark A. Exley, Donal O’Shea, Emmanuel Scotet, Andrew E. Hogan and Derek G. Doherty
    J Immunol July 1, 2013, 191 (1) 30-34; DOI: https://doi.org/10.4049/jimmunol.1300121

ANTIGEN RECOGNITION AND RESPONSES

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    Naturally Occurring ERAP1 Haplotypes Encode Functionally Distinct Alleles with Fine Substrate Specificity
    Emma Reeves, Christopher J. Edwards, Tim Elliott and Edward James
    J Immunol July 1, 2013, 191 (1) 35-43; DOI: https://doi.org/10.4049/jimmunol.1300598
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    Independent Expansion of Epitope-Specific Plasma Cell Responses upon HIV-1 Envelope Glycoprotein Immunization
    Mattias N. E. Forsell, Martina Soldemo, Pia Dosenovic, Richard T. Wyatt, Mikael C. I. Karlsson and Gunilla B. Karlsson Hedestam
    J Immunol July 1, 2013, 191 (1) 44-51; DOI: https://doi.org/10.4049/jimmunol.1203087
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    Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses
    Damien Zanker, Jason Waithman, Jonathan W. Yewdell and Weisan Chen
    J Immunol July 1, 2013, 191 (1) 52-59; DOI: https://doi.org/10.4049/jimmunol.1300802
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    Human Plasmacytoid Dendritic Cells Efficiently Capture HIV-1 Envelope Glycoproteins via CD4 for Antigen Presentation
    Kerrie J. Sandgren, Anna Smed-Sörensen, Mattias N. Forsell, Martina Soldemo, William C. Adams, Frank Liang, Leif Perbeck, Richard A. Koup, Richard T. Wyatt, Gunilla B. Karlsson Hedestam and Karin Loré
    J Immunol July 1, 2013, 191 (1) 60-69; DOI: https://doi.org/10.4049/jimmunol.1202489

AUTOIMMUNITY

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    Dendritic Cell–Dependent In Vivo Generation of Autoregulatory T Cells by Antidiabetogenic MHC Class II
    Sue Tsai, Pau Serra, Xavier Clemente-Casares, Robyn M. Slattery and Pere Santamaria
    J Immunol July 1, 2013, 191 (1) 70-82; DOI: https://doi.org/10.4049/jimmunol.1300168
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    Ectopic Expression of Epidermal Antigens Renders the Lung a Target Organ in Paraneoplastic Pemphigus
    Tsuyoshi Hata, Shuhei Nishimoto, Keisuke Nagao, Hayato Takahashi, Kazue Yoshida, Manabu Ohyama, Taketo Yamada, Koichiro Asano and Masayuki Amagai
    J Immunol July 1, 2013, 191 (1) 83-90; DOI: https://doi.org/10.4049/jimmunol.1203536
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    IFN-γ–Producing Effector CD8 T Lymphocytes Cause Immune Glomerular Injury by Recognizing Antigen Presented as Immune Complex on Target Tissue
    Ken Tsumiyama, Akira Hashiramoto, Mai Takimoto, Sachiyo Tsuji-Kawahara, Masaaki Miyazawa and Shunichi Shiozawa
    J Immunol July 1, 2013, 191 (1) 91-96; DOI: https://doi.org/10.4049/jimmunol.1203217
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    Intrinsic Molecular Factors Cause Aberrant Expansion of the Splenic Marginal Zone B Cell Population in Nonobese Diabetic Mice
    Jessica Stolp, Eliana Mariño, Marcel Batten, Frederic Sierro, Selwyn L. Cox, Shane T. Grey and Pablo A. Silveira
    J Immunol July 1, 2013, 191 (1) 97-109; DOI: https://doi.org/10.4049/jimmunol.1203252
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    Ro60 Requires Y3 RNA for Cell Surface Exposure and Inflammation Associated with Cardiac Manifestations of Neonatal Lupus
    Joanne H. Reed, Soyeong Sim, Sandra L. Wolin, Robert M. Clancy and Jill P. Buyon
    J Immunol July 1, 2013, 191 (1) 110-116; DOI: https://doi.org/10.4049/jimmunol.1202849
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    The Disease-Ameliorating Function of Autoregulatory CD8 T Cells Is Mediated by Targeting of Encephalitogenic CD4 T Cells in Experimental Autoimmune Encephalomyelitis
    Sterling B. Ortega, Venkatesh P. Kashi, Andrew F. Tyler, Khrishen Cunnusamy, Jason P. Mendoza and Nitin J. Karandikar
    J Immunol July 1, 2013, 191 (1) 117-126; DOI: https://doi.org/10.4049/jimmunol.1300452

CLINICAL AND HUMAN IMMUNOLOGY

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    Antibody-Secreting Cells with a Phenotype of Ki-67low, CD138high, CD31high, and CD38high Secrete Nonspecific IgM during Primary Hepatitis A Virus Infection
    Seokchan Hong, Hyun Woong Lee, Dong-Yeop Chang, Sooseong You, Jihye Kim, Jun Yong Park, Sang Hoon Ahn, Dongeun Yong, Kwang-Hyub Han, Ook Joon Yoo and Eui-Cheol Shin
    J Immunol July 1, 2013, 191 (1) 127-134; DOI: https://doi.org/10.4049/jimmunol.1203540
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    Autologous Tax-Specific CTL Therapy in a Primary Adult T Cell Leukemia/Lymphoma Cell–Bearing NOD/Shi-scid, IL-2Rγnull Mouse Model
    Ayako Masaki, Takashi Ishida, Susumu Suzuki, Asahi Ito, Fumiko Mori, Fumihiko Sato, Tomoko Narita, Tomiko Yamada, Masaki Ri, Shigeru Kusumoto, Hirokazu Komatsu, Yuetsu Tanaka, Akio Niimi, Hiroshi Inagaki, Shinsuke Iida and Ryuzo Ueda
    J Immunol July 1, 2013, 191 (1) 135-144; DOI: https://doi.org/10.4049/jimmunol.1202692
  • Open Access
    Fetal–Maternal Alignment of Regulatory T Cells Correlates with IL-10 and Bcl-2 Upregulation in Pregnancy

    Author Choice Article

    Brigitte Santner-Nanan, Kathrin Straubinger, Peter Hsu, Grant Parnell, Ben Tang, Bei Xu, Angela Makris, Annemarie Hennessy, Michael J. Peek, Dirk H. Busch, Clarissa Prazeres da Costa and Ralph Nanan
    J Immunol July 1, 2013, 191 (1) 145-153; DOI: https://doi.org/10.4049/jimmunol.1203165

IMMUNE REGULATION

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    LIGHT (TNFSF14/CD258) Is a Decisive Factor for Recovery from Experimental Autoimmune Encephalomyelitis
    Paula Maña, David Liñares, Diego G. Silva, Susan Fordham, Stefanie Scheu, Klaus Pfeffer, Maria Staykova and Edward M. Bertram
    J Immunol July 1, 2013, 191 (1) 154-163; DOI: https://doi.org/10.4049/jimmunol.1203016
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    Nitric Oxide–Induced Regulatory T Cells Inhibit Th17 but Not Th1 Cell Differentiation and Function
    Wanda Niedbala, Anne-Gaelle Besnard, Hui R. Jiang, Jose C. Alves-Filho, Sandra Y. Fukada, Daniela Nascimento, Akio Mitani, Peter Pushparaj, Mohammed H. Alqahtani and Foo Y. Liew
    J Immunol July 1, 2013, 191 (1) 164-170; DOI: https://doi.org/10.4049/jimmunol.1202580
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    Endogenous Galectin-1 Exerts Tonic Inhibition on Experimental Arthritis
    Asif J. Iqbal, Dianne Cooper, Alexander Vugler, Beatrice R. Gittens, Adrian Moore and Mauro Perretti
    J Immunol July 1, 2013, 191 (1) 171-177; DOI: https://doi.org/10.4049/jimmunol.1203291
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    An Essential Role for C5aR Signaling in the Optimal Induction of a Malaria-Specific CD4+ T Cell Response by a Whole-Killed Blood-Stage Vaccine
    Taiping Liu, Guilian Xu, Bo Guo, Yong Fu, Yuan Qiu, Yan Ding, Hong Zheng, Xiaolan Fu, Yuzhang Wu and Wenyue Xu
    J Immunol July 1, 2013, 191 (1) 178-186; DOI: https://doi.org/10.4049/jimmunol.1201190
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    FoxO1 Controls Effector-to-Memory Transition and Maintenance of Functional CD8 T Cell Memory
    Melba Marie Tejera, Eui Ho Kim, Jeremy A. Sullivan, Erin H. Plisch and M. Suresh
    J Immunol July 1, 2013, 191 (1) 187-199; DOI: https://doi.org/10.4049/jimmunol.1300331
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    Phosphatidylinositol 3-Kinase–Independent Signaling Pathways Contribute to ICOS-Mediated T Cell Costimulation in Acute Graft-Versus-Host Disease in Mice
    Jun Li, Jessica Heinrichs, Julien Leconte, Kelley Haarberg, Kenrick Semple, Chen Liu, Mathieu Gigoux, Mara Kornete, Ciriaco A. Piccirillo, Woong-Kyung Suh and Xue-Zhong Yu
    J Immunol July 1, 2013, 191 (1) 200-207; DOI: https://doi.org/10.4049/jimmunol.1203485

IMMUNOTHERAPY AND VACCINES

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    Amino Acid Copolymers That Alleviate Experimental Autoimmune Encephalomyelitis In Vivo Interact with Heparan Sulfates and Glycoprotein 96 in APCs
    Paul-Albert Koenig, Eric Spooner, Norio Kawamoto, Jack L. Strominger and Hidde L. Ploegh
    J Immunol July 1, 2013, 191 (1) 208-216; DOI: https://doi.org/10.4049/jimmunol.1300345
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    Peptide Vaccines and Peptidomimetics of EGFR (HER-1) Ligand Binding Domain Inhibit Cancer Cell Growth In Vitro and In Vivo
    Kevin Chu Foy, Ruthie M. Wygle, Megan J. Miller, Jay P. Overholser, Tanios Bekaii-Saab and Pravin T. P. Kaumaya
    J Immunol July 1, 2013, 191 (1) 217-227; DOI: https://doi.org/10.4049/jimmunol.1300231

INFECTIOUS DISEASE AND HOST RESPONSE

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    Enhanced T Cell Function in a Mouse Model of Human Glycosylation
    George Buchlis, Pamela Odorizzi, Paula C. Soto, Oliver M. T. Pearce, Daniel J. Hui, Martha S. Jordan, Ajit Varki, E. John Wherry and Katherine A. High
    J Immunol July 1, 2013, 191 (1) 228-237; DOI: https://doi.org/10.4049/jimmunol.1202905
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    Scavenger Receptor A Modulates the Immune Response to Pulmonary Cryptococcus neoformans Infection
    Yafeng Qiu, Jeremy K. Dayrit, Michael J. Davis, Jacob F. Carolan, John J. Osterholzer, Jeffrey L. Curtis and Michal A. Olszewski
    J Immunol July 1, 2013, 191 (1) 238-248; DOI: https://doi.org/10.4049/jimmunol.1203435
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    Cryptococcus gattii Is Killed by Dendritic Cells, but Evades Adaptive Immunity by Failing To Induce Dendritic Cell Maturation
    Shaunna M. Huston, Shu Shun Li, Danuta Stack, Martina Timm-McCann, Gareth J. Jones, Anowara Islam, Byron M. Berenger, Richard F. Xiang, Pina Colarusso and Christopher H. Mody
    J Immunol July 1, 2013, 191 (1) 249-261; DOI: https://doi.org/10.4049/jimmunol.1202707
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    Leishmania-Infected MHC Class IIhigh Dendritic Cells Polarize CD4+ T Cells toward a Nonprotective T-bet+ IFN-γ+ IL-10+ Phenotype
    Mariana Resende, Diana Moreira, Jorge Augusto, Joana Cunha, Bruno Neves, Maria Teresa Cruz, Jérôme Estaquier, Anabela Cordeiro-da-Silva and Ricardo Silvestre
    J Immunol July 1, 2013, 191 (1) 262-273; DOI: https://doi.org/10.4049/jimmunol.1203518
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    Dormant Mycobacterium tuberculosis Fails To Block Phagosome Maturation and Shows Unexpected Capacity To Stimulate Specific Human T Lymphocytes
    Sabrina Mariotti, Manuela Pardini, Maria Cristina Gagliardi, Raffaela Teloni, Federico Giannoni, Maurizio Fraziano, Francesco Lozupone, Stefania Meschini and Roberto Nisini
    J Immunol July 1, 2013, 191 (1) 274-282; DOI: https://doi.org/10.4049/jimmunol.1202900
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    The IL-33/ST2 Pathway Controls Coxsackievirus B5–Induced Experimental Pancreatitis
    Renata Sesti-Costa, Grace K. Silva, José L. Proença-Módena, Daniela Carlos, Maria L. Silva, José C. Alves-Filho, Eurico Arruda, Foo Y. Liew and João S. Silva
    J Immunol July 1, 2013, 191 (1) 283-292; DOI: https://doi.org/10.4049/jimmunol.1202806
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    MicroRNA-146a Feedback Suppresses T Cell Immune Function by Targeting Stat1 in Patients with Chronic Hepatitis B
    Saifeng Wang, Xiaojun Zhang, Ying Ju, Bao Zhao, Xiaoli Yan, Jun Hu, Lei Shi, Lebing Yang, Zhibo Ma, Lizhao Chen, Yali Liu, Zhongping Duan, Xinyue Chen and Songdong Meng
    J Immunol July 1, 2013, 191 (1) 293-301; DOI: https://doi.org/10.4049/jimmunol.1202100
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    Influenza A Virus Infection Impairs Mycobacteria-Specific T Cell Responses and Mycobacterial Clearance in the Lung during Pulmonary Coinfection
    Manuela Flórido, Michael A. Grima, Caitlin M. Gillis, Yingju Xia, Stephen J. Turner, James A. Triccas, John Stambas and Warwick J. Britton
    J Immunol July 1, 2013, 191 (1) 302-311; DOI: https://doi.org/10.4049/jimmunol.1202824
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    Regulatory CD8+ T Cells Associated with Erosion of Immune Surveillance in Persistent Virus Infection Suppress In Vitro and Have a Reversible Proliferative Defect
    Zhuting Hu, Weijun Zhang and Edward J. Usherwood
    J Immunol July 1, 2013, 191 (1) 312-322; DOI: https://doi.org/10.4049/jimmunol.1201773

INNATE IMMUNITY AND INFLAMMATION

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    Synergistic Expression of the CXCL10 Gene in Response to IL-1β and IFN-γ Involves NF-κB, Phosphorylation of STAT1 at Tyr701, and Acetylation of Histones H3 and H4
    Susan J. Burke, Matthew R. Goff, Danhong Lu, David Proud, Michael D. Karlstad and J. Jason Collier
    J Immunol July 1, 2013, 191 (1) 323-336; DOI: https://doi.org/10.4049/jimmunol.1300344
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    The Bacterial Quorum-Sensing Signal Molecule N-3-Oxo-Dodecanoyl-l-Homoserine Lactone Reciprocally Modulates Pro- and Anti-Inflammatory Cytokines in Activated Macrophages
    Yifat Glucksam-Galnoy, Roy Sananes, Nava Silberstein, Pnina Krief, Vladimir V. Kravchenko, Michael M. Meijler and Tsaffrir Zor
    J Immunol July 1, 2013, 191 (1) 337-344; DOI: https://doi.org/10.4049/jimmunol.1300368
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    β-Defensins Activate Human Mast Cells via Mas-Related Gene X2
    Hariharan Subramanian, Kshitij Gupta, Donguk Lee, Arzu K. Bayir, Harry Ahn and Hydar Ali
    J Immunol July 1, 2013, 191 (1) 345-352; DOI: https://doi.org/10.4049/jimmunol.1300023
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    Staphylococcus aureus Formyl Peptide Receptor–like 1 Inhibitor (FLIPr) and Its Homologue FLIPr-like Are Potent FcγR Antagonists That Inhibit IgG-Mediated Effector Functions
    Annette M. Stemerding, Jörg Köhl, Manoj K. Pandey, Annemarie Kuipers, Jeanette H. Leusen, Peter Boross, Maaike Nederend, Gestur Vidarsson, Annemarie Y. L. Weersink, Jan G. J. van de Winkel, Kok P. M. van Kessel and Jos A. G. van Strijp
    J Immunol July 1, 2013, 191 (1) 353-362; DOI: https://doi.org/10.4049/jimmunol.1203243
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    Both NK Cell–Intrinsic and –Extrinsic STAT1 Signaling Are Required for NK Cell Response against Vaccinia Virus
    Carl Fortin, Xiaopei Huang and Yiping Yang
    J Immunol July 1, 2013, 191 (1) 363-368; DOI: https://doi.org/10.4049/jimmunol.1202714
  • Open Access
    CD166/ALCAM Mediates Proinflammatory Effects of S100B in Delayed Type Hypersensitivity

    Author Choice Article

    Rüdiger von Bauer, Dimitrios Oikonomou, Alba Sulaj, Sawsan Mohammed, Agnes Hotz-Wagenblatt, Hermann-Josef Gröne, Bernd Arnold, Christine Falk, Dorit Luethje, Axel Erhardt, David M. Stern, Angelika Bierhaus and Peter P. Nawroth
    J Immunol July 1, 2013, 191 (1) 369-377; DOI: https://doi.org/10.4049/jimmunol.1201864
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    Low Levels of Insulin-like Growth Factor-1 Contribute to Alveolar Macrophage Dysfunction in Cystic Fibrosis
    Jamie L. Bessich, Amanda B. Nymon, Lisa A. Moulton, Dana Dorman and Alix Ashare
    J Immunol July 1, 2013, 191 (1) 378-385; DOI: https://doi.org/10.4049/jimmunol.1300221
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    MAPK Kinase 3 Potentiates Chlamydia HSP60-Induced Inflammatory Response through Distinct Activation of NF-κB
    Yanhua Kang, Fang Wang, Zhe Lu, Hangjie Ying, Hang Zhang, Wen Ding, Cuili Wang and Liyun Shi
    J Immunol July 1, 2013, 191 (1) 386-394; DOI: https://doi.org/10.4049/jimmunol.1300481
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    Cyclooxygenase-2 Deficiency in Macrophages Leads to Defective p110γ PI3K Signaling and Impairs Cell Adhesion and Migration
    Manuel D. Díaz-Muñoz, Inés C. Osma-García, Miguel A. Íñiguez and Manuel Fresno
    J Immunol July 1, 2013, 191 (1) 395-406; DOI: https://doi.org/10.4049/jimmunol.1202002
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    Myeloid Hypoxia-Inducible Factor-1α Is Essential for Skeletal Muscle Regeneration in Mice
    Nina Scheerer, Nathalie Dehne, Christian Stockmann, Sandra Swoboda, Hideo A. Baba, Agnes Neugebauer, Randall S. Johnson and Joachim Fandrey
    J Immunol July 1, 2013, 191 (1) 407-414; DOI: https://doi.org/10.4049/jimmunol.1103779
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    Differential Involvement of Th1 and Th17 in Pathogenic Autoimmune Processes Triggered by Different TLR Ligands
    Guangpu Shi, Barbara P. Vistica, Lindsey F. Nugent, Cuiyan Tan, Eric F. Wawrousek, Dennis M. Klinman and Igal Gery
    J Immunol July 1, 2013, 191 (1) 415-423; DOI: https://doi.org/10.4049/jimmunol.1201732
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    GILZ Overexpression Inhibits Endothelial Cell Adhesive Function through Regulation of NF-κB and MAPK Activity
    Qiang Cheng, Huapeng Fan, Devi Ngo, Elaine Beaulieu, Patrick Leung, Camden Y. Lo, Rosemary Burgess, Yvonne G. van der Zwan, Stefan J. White, Levon M. Khachigian, Michael J. Hickey and Eric F. Morand
    J Immunol July 1, 2013, 191 (1) 424-433; DOI: https://doi.org/10.4049/jimmunol.1202662
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    Optimal Germinal Center B Cell Activation and T-Dependent Antibody Responses Require Expression of the Mouse Complement Receptor Cr1
    Luke R. Donius, Jennifer M. Handy, Janis J. Weis and John H. Weis
    J Immunol July 1, 2013, 191 (1) 434-447; DOI: https://doi.org/10.4049/jimmunol.1203176

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Role of High Endothelial Venule–Expressed Heparan Sulfate in Chemokine Presentation and Lymphocyte Homing
    Koichiro Tsuboi, Jotaro Hirakawa, Emiko Seki, Yasuyuki Imai, Yu Yamaguchi, Minoru Fukuda and Hiroto Kawashima
    J Immunol July 1, 2013, 191 (1) 448-455; DOI: https://doi.org/10.4049/jimmunol.1203061
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    Structural Evaluation of a Mimicry-Recognizing Paratope: Plasticity in Antigen–Antibody Interactions Manifests in Molecular Mimicry
    Suman Tapryal, Vineet Gaur, Kanwal J. Kaur and Dinakar M. Salunke
    J Immunol July 1, 2013, 191 (1) 456-463; DOI: https://doi.org/10.4049/jimmunol.1203260
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    Inhibition of Histone Deacetylase Activity Suppresses IFN-γ Induction of Tripartite Motif 22 via CHIP-Mediated Proteasomal Degradation of IRF-1
    Bo Gao, Yaxin Wang, Wei Xu, Shangshan Li, Qiao Li and Sidong Xiong
    J Immunol July 1, 2013, 191 (1) 464-471; DOI: https://doi.org/10.4049/jimmunol.1203533
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    Complete TCR-α Gene Locus Control Region Activity in T Cells Derived In Vitro from Embryonic Stem Cells
    Armin Lahiji, Martina Kučerová-Levisohn, Jordana Lovett, Roxanne Holmes, Juan Carlos Zúñiga-Pflücker and Benjamin D. Ortiz
    J Immunol July 1, 2013, 191 (1) 472-479; DOI: https://doi.org/10.4049/jimmunol.1300521

TRANSPLANTATION

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    Unconventional RORγt+ T Cells Drive Hepatic Ischemia Reperfusion Injury
    Elke Eggenhofer, Jordi Rovira, Manije Sabet-Baktach, Anja Groell, Marcus N. Scherer, Marc-Hendrik Dahlke, Stefan A. Farkas, Martin Loss, Gudrun E. Koehl, Sven A. Lang, Michael Melter, Hans J. Schlitt, Edward K. Geissler and Alexander Kroemer
    J Immunol July 1, 2013, 191 (1) 480-487; DOI: https://doi.org/10.4049/jimmunol.1202975
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    Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells
    Tao Wu, James S. Young, Heather Johnston, Xiong Ni, Ruishu Deng, Jeremy Racine, Miao Wang, Audrey Wang, Ivan Todorov, Jianmin Wang and Defu Zeng
    J Immunol July 1, 2013, 191 (1) 488-499; DOI: https://doi.org/10.4049/jimmunol.1300657

TUMOR IMMUNOLOGY

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    Critical Role of Dendritic Cell–Derived IL-27 in Antitumor Immunity through Regulating the Recruitment and Activation of NK and NKT Cells
    Jun Wei, Siyuan Xia, Huayan Sun, Song Zhang, Jingya Wang, Huiyuan Zhao, Xiaoli Wu, Xi Chen, Jianlei Hao, Xinglong Zhou, Zhengmao Zhu, Xiang Gao, Jian-xin Gao, Puyue Wang, Zhenzhou Wu, Liqing Zhao and Zhinan Yin
    J Immunol July 1, 2013, 191 (1) 500-508; DOI: https://doi.org/10.4049/jimmunol.1300328
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This Issue

The Journal of Immunology: 191 (1)
The Journal of Immunology
Vol. 191, Issue 1
1 Jul 2013
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606