Kim, C., C. C. Marchal, J. Penninger, and M. C. Dinauer, 2003. The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions. J. Immunol. 171: 4425–4430.
The labeling of the legend for Fig. 4A was incorrect. The correct labeling should read “□, Wild-type; ▪, Vav1−/−.”
The corrected figure legend is as follows:
FIGURE 4. Neutrophil migration in response to FMLP. A, Migration of BM neutrophils was assayed in a modified Boyden chamber using FMLP (10−7–10−5 μM). The numbers of cells migrating to the lower side of the filter in chambers containing buffer alone were also counted in samples assayed in parallel (27 ± 10 for wild-type neutrophils and 14 ± 11 for Vav1−/−; n = 8, p < 0.01 wild-type vs Vav1−/−), and have been subtracted from the data shown for FMLP-treated groups. □, Wild-type; ▪, Vav1−/−. Data are expressed as mean ± SEM. *, p < 0.02, wild-type vs Vav1−/− (paired t test). B, Peripheral blood neutrophil concentrations in wild-type or Vav1−/− mice 90 min following s.c. injection of 200 μl of sterile saline (□), 20 μM FMLP (▪), or 250 ng/ml IL-8 (hatched bars) (n = 5–9 mice in each group). Data are expressed as mean ± SEM. *, p < 0.01 (Mann-Whitney U test).
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