On the cover: H&E image of colonic tissue from Il10^−/−;NF-κB^EGFP mice treated with the PI3K inhibitor wortmannin. The image displays intact crypts composed of numerous goblet cells tightly aligned above the pink muscular layer. Sun, X., B. Liu, R. B. Sartor, and C. Jobin. 2013. Phosphatidylinositol 3-kinase-γ signaling promotes Campylobacter jejuni–induced colitis through neutrophil recruitment in mice. J. Immunol. 190: 357–365.