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The Journal of Immunology

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Table of Contents

January 1, 2013; Volume 190,Issue 1

IN THIS ISSUE

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    In This Issue
    J Immunol January 1, 2013, 190 (1) 1-2; DOI: https://doi.org/10.4049/jimmunol.1290078

PILLARS OF IMMUNOLOGY

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    MyD88: A Critical Adaptor Protein in Innate Immunity Signal Transduction
    Neil Warner and Gabriel Núñez
    J Immunol January 1, 2013, 190 (1) 3-4; DOI: https://doi.org/10.4049/jimmunol.1203103
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    Pillars Article: MyD88: An Adapter That Recruits IRAK to the IL-1 Receptor Complex. Immunity. 1997. 7: 837–847
    Holger Wesche, William J. Henzel, Wendy Shillinglaw, Shyun Li and Zhaodan Cao
    J Immunol January 1, 2013, 190 (1) 5-15;
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    Pillars Article: IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling. Science. 1997. 278: 1612–1615
    Marta Muzio, Jian Ni, Ping Feng and Vishva M. Dixit
    J Immunol January 1, 2013, 190 (1) 16-19;

CUTTING EDGE

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    Cutting Edge: Ly9 (CD229), a SLAM Family Receptor, Negatively Regulates the Development of Thymic Innate Memory-like CD8+ T and Invariant NKT Cells
    Jordi Sintes, Marta Cuenca, Xavier Romero, Ricardo Bastos, Cox Terhorst, Ana Angulo and Pablo Engel
    J Immunol January 1, 2013, 190 (1) 21-26; DOI: https://doi.org/10.4049/jimmunol.1202435

ANTIGEN RECOGNITION AND RESPONSES

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    Rho-Family GTPase Cdc42 Controls Migration of Langerhans Cells In Vivo
    Nancy Luckashenak, Anna Wähe, Katharina Breit, Cord Brakebusch and Thomas Brocker
    J Immunol January 1, 2013, 190 (1) 27-35; DOI: https://doi.org/10.4049/jimmunol.1201082
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    Increasing Viral Dose Causes a Reversal in CD8+ T Cell Immunodominance during Primary Influenza Infection due to Differences in Antigen Presentation, T Cell Avidity, and Precursor Numbers
    Fabio Luciani, Megan T. Sanders, Sara Oveissi, Ken C. Pang and Weisan Chen
    J Immunol January 1, 2013, 190 (1) 36-47; DOI: https://doi.org/10.4049/jimmunol.1200089

AUTOIMMUNITY

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    An HLA-DRB1–Coded Signal Transduction Ligand Facilitates Inflammatory Arthritis: A New Mechanism of Autoimmunity
    Joseph Holoshitz, Ying Liu, Jiaqi Fu, Jeena Joseph, Song Ling, Alessandro Colletta, Prannda Sharma, Dana Begun, Steven Goldstein and Russell Taichman
    J Immunol January 1, 2013, 190 (1) 48-57; DOI: https://doi.org/10.4049/jimmunol.1202150
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    Early Growth Response Gene-2 Controls IL-17 Expression and Th17 Differentiation by Negatively Regulating Batf
    Tizong Miao, Meera Raymond, Punamdip Bhullar, Emma Ghaffari, Alistair L. J. Symonds, Ute C. Meier, Gavin Giovannoni, Suling Li and Ping Wang
    J Immunol January 1, 2013, 190 (1) 58-65; DOI: https://doi.org/10.4049/jimmunol.1200868

CLINICAL AND HUMAN IMMUNOLOGY

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    Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells
    Andrew N. Harman, Chris R. Bye, Najla Nasr, Kerrie J. Sandgren, Min Kim, Sarah K. Mercier, Rachel A. Botting, Sharon R. Lewin, Anthony L. Cunningham and Paul U. Cameron
    J Immunol January 1, 2013, 190 (1) 66-79; DOI: https://doi.org/10.4049/jimmunol.1200779
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    Association between Magnitude of the Virus-Specific Plasmablast Response and Disease Severity in Dengue Patients
    Tatiana M. Garcia-Bates, Marli T. Cordeiro, Eduardo J. M. Nascimento, Amanda P. Smith, Klécia M. Soares de Melo, Sean P. McBurney, Jared D. Evans, Ernesto T. A. Marques Jr. and Simon M. Barratt-Boyes
    J Immunol January 1, 2013, 190 (1) 80-87; DOI: https://doi.org/10.4049/jimmunol.1103350

IMMUNE REGULATION

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    TIM-3 Regulates Innate Immune Cells To Induce Fetomaternal Tolerance
    Lola Chabtini, Bechara Mfarrej, Marwan Mounayar, Bing Zhu, Ibrahim Batal, Pranal J. Dakle, Brian D. Smith, Olaf Boenisch, Nader Najafian, Hisaya Akiba, Hideo Yagita and Indira Guleria
    J Immunol January 1, 2013, 190 (1) 88-96; DOI: https://doi.org/10.4049/jimmunol.1202176
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    Apoptotic Programs Are Determined during Lineage Commitment of CD4+ T Effectors: Selective Regulation of T Effector-Memory Apoptosis by Inducible Nitric Oxide Synthase
    Divya Purushothaman, Nimi Marcel, Megha Garg, Rasika Venkataraman and Apurva Sarin
    J Immunol January 1, 2013, 190 (1) 97-105; DOI: https://doi.org/10.4049/jimmunol.1103694
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    Quorum Sensing Contributes to Activated IgM-Secreting B Cell Homeostasis
    Caroline Montaudouin, Marie Anson, Yi Hao, Susanne V. Duncker, Tahia Fernandez, Emmanuelle Gaudin, Michael Ehrenstein, William G. Kerr, Jean-Hervé Colle, Pierre Bruhns, Marc Daëron and António A. Freitas
    J Immunol January 1, 2013, 190 (1) 106-114; DOI: https://doi.org/10.4049/jimmunol.1200907
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    CD11b/CD18 (Mac-1) Is a Novel Surface Receptor for Extracellular Double-Stranded RNA To Mediate Cellular Inflammatory Responses
    Hui Zhou, Jieying Liao, Jim Aloor, Hui Nie, Belinda C. Wilson, Michael B. Fessler, Hui-Ming Gao and Jau-Shyong Hong
    J Immunol January 1, 2013, 190 (1) 115-125; DOI: https://doi.org/10.4049/jimmunol.1202136
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    Immunodeficiency and Autoimmunity in H2-O–Deficient Mice
    Yapeng Gu, Peter E. Jensen and Xinjian Chen
    J Immunol January 1, 2013, 190 (1) 126-137; DOI: https://doi.org/10.4049/jimmunol.1200993
  • Open Access
    Blocking A2B Adenosine Receptor Alleviates Pathogenesis of Experimental Autoimmune Encephalomyelitis via Inhibition of IL-6 Production and Th17 Differentiation

    Author Choice Article

    Wei Wei, Changsheng Du, Jie Lv, Guixian Zhao, Zhenxin Li, Zhiying Wu, György Haskó and Xin Xie
    J Immunol January 1, 2013, 190 (1) 138-146; DOI: https://doi.org/10.4049/jimmunol.1103721
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    A Phospholipase C-γ1–Independent, RasGRP1-ERK–Dependent Pathway Drives Lymphoproliferative Disease in Linker for Activation of T Cells–Y136F Mutant Mice
    Robert L. Kortum, Alexandre K. Rouquette-Jazdanian, Michihiko Miyaji, Robert K. Merrill, Evan Markegard, John M. Pinski, Amelia Wesselink, Nandan N. Nath, Clayton P. Alexander, Wenmei Li, Noemi Kedei, Jeroen P. Roose, Peter M. Blumberg, Lawrence E. Samelson and Connie L. Sommers
    J Immunol January 1, 2013, 190 (1) 147-158; DOI: https://doi.org/10.4049/jimmunol.1201458
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    Nuclear Translocation of MEK1 Triggers a Complex T Cell Response through the Corepressor Silencing Mediator of Retinoid and Thyroid Hormone Receptor
    Lei Guo, Chaoyu Chen, Qiaoling Liang, Mohammad Zunayet Karim, Magdalena M. Gorska and Rafeul Alam
    J Immunol January 1, 2013, 190 (1) 159-167; DOI: https://doi.org/10.4049/jimmunol.1201657
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    Cleavage of Anti-Apoptotic Bcl-2 Family Members after TCR Stimulation Contributes to the Decision between T Cell Activation and Apoptosis
    Alan D. Guerrero, Robert L. Welschhans, Min Chen and Jin Wang
    J Immunol January 1, 2013, 190 (1) 168-173; DOI: https://doi.org/10.4049/jimmunol.1201610
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    SLAT Regulates CD8+ T Cell Clonal Expansion in a Cdc42- and NFAT1-Dependent Manner
    Sonia Feau, Stephen P. Schoenberger, Amnon Altman and Stéphane Bécart
    J Immunol January 1, 2013, 190 (1) 174-183; DOI: https://doi.org/10.4049/jimmunol.1201685
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    Isolation of Human CD4/CD8 Double-Positive, Graft-Versus-Host Disease–Protective, Minor Histocompatibility Antigen–Specific Regulatory T Cells and of a Novel HLA-DR7–Restricted HY-Specific CD4 Clone
    Assia Eljaafari, Ozel Yuruker, Christophe Ferrand, Annie Farre, Caroline Addey, Marie-Laure Tartelin, Xavier Thomas, Pierre Tiberghien, Elizabeth Simpson, Dominique Rigal and Diane Scott
    J Immunol January 1, 2013, 190 (1) 184-194; DOI: https://doi.org/10.4049/jimmunol.1201163

IMMUNOGENETICS

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    Reduced Surface Expression of TLR4 by a V254I Point Mutation Accounts for the Low Lipopolysaccharide Responder Phenotype of BALB/c B Cells
    Hiroki Tsukamoto, Kenji Fukudome, Shoko Takao, Naoko Tsuneyoshi, Shoichiro Ohta, Yoshinori Nagai, Hideyuki Ihara, Kensuke Miyake, Yoshitaka Ikeda and Masao Kimoto
    J Immunol January 1, 2013, 190 (1) 195-204; DOI: https://doi.org/10.4049/jimmunol.1201047

IMMUNOTHERAPY AND VACCINES

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    Impact of IgA Constant Domain on HIV-1 Neutralizing Function of Monoclonal Antibody F425A1g8
    Xiaocong Yu, Mark Duval, Christopher Lewis, Melissa A. Gawron, Rijian Wang, Marshall R. Posner and Lisa A. Cavacini
    J Immunol January 1, 2013, 190 (1) 205-210; DOI: https://doi.org/10.4049/jimmunol.1201469
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    In Vivo Blockade of the PD-1 Receptor Suppresses HIV-1 Viral Loads and Improves CD4+ T Cell Levels in Humanized Mice
    Brent E. Palmer, C. Preston Neff, Jonathan LeCureux, Angelica Ehler, Michelle DSouza, Leila Remling-Mulder, Alan J. Korman, Andrew P. Fontenot and Ramesh Akkina
    J Immunol January 1, 2013, 190 (1) 211-219; DOI: https://doi.org/10.4049/jimmunol.1201108
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    Toward Animal Cell Culture–Based Influenza Vaccine Design: Viral Hemagglutinin N-Glycosylation Markedly Impacts Immunogenicity
    Julia Hütter, Jana V. Rödig, Dirk Höper, Peter H. Seeberger, Udo Reichl, Erdmann Rapp and Bernd Lepenies
    J Immunol January 1, 2013, 190 (1) 220-230; DOI: https://doi.org/10.4049/jimmunol.1201060
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    Ofatumumab Is More Efficient than Rituximab in Lysing B Chronic Lymphocytic Leukemia Cells in Whole Blood and in Combination with Chemotherapy
    Luca Bologna, Elisa Gotti, Fabio Da Roit, Tamara Intermesoli, Alessandro Rambaldi, Martino Introna and Josée Golay
    J Immunol January 1, 2013, 190 (1) 231-239; DOI: https://doi.org/10.4049/jimmunol.1202645

INFECTIOUS DISEASE AND HOST RESPONSE

  • Open Access
    A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

    Author Choice Article

    Anja Bengtsson, Louise Joergensen, Thomas S. Rask, Rebecca W. Olsen, Marianne A. Andersen, Louise Turner, Thor G. Theander, Lars Hviid, Matthew K. Higgins, Alister Craig, Alan Brown and Anja T. R. Jensen
    J Immunol January 1, 2013, 190 (1) 240-249; DOI: https://doi.org/10.4049/jimmunol.1202578
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    MARCO Is Required for TLR2- and Nod2-Mediated Responses to Streptococcus pneumoniae and Clearance of Pneumococcal Colonization in the Murine Nasopharynx
    Michael G. Dorrington, Aoife M. Roche, Sarah E. Chauvin, Zhongyuan Tu, Karen L. Mossman, Jeffrey N. Weiser and Dawn M. E. Bowdish
    J Immunol January 1, 2013, 190 (1) 250-258; DOI: https://doi.org/10.4049/jimmunol.1202113
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    A Pathogenic Role for CD4+ T Cells during Chikungunya Virus Infection in Mice
    Teck-Hui Teo, Fok-Moon Lum, Carla Claser, Valeria Lulla, Aleksei Lulla, Andres Merits, Laurent Rénia and Lisa F. P. Ng
    J Immunol January 1, 2013, 190 (1) 259-269; DOI: https://doi.org/10.4049/jimmunol.1202177
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    IFN-γ from CD4 T Cells Is Essential for Host Survival and Enhances CD8 T Cell Function during Mycobacterium tuberculosis Infection
    Angela M. Green, Robert DiFazio and JoAnne L. Flynn
    J Immunol January 1, 2013, 190 (1) 270-277; DOI: https://doi.org/10.4049/jimmunol.1200061
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    Lipoproteins Are Major Targets of the Polyclonal Human T Cell Response to Mycobacterium tuberculosis
    Chetan Seshadri, Marie T. Turner, David M. Lewinsohn, D. Branch Moody and Ildiko Van Rhijn
    J Immunol January 1, 2013, 190 (1) 278-284; DOI: https://doi.org/10.4049/jimmunol.1201667
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    Memory CD4+ T Cells Are Required for Optimal NK Cell Effector Functions against the Opportunistic Fungal Pathogen Pneumocystis murina
    Michelle N. Kelly, Mingquan Zheng, Sanbao Ruan, Jay Kolls, Alain D’Souza and Judd E. Shellito
    J Immunol January 1, 2013, 190 (1) 285-295; DOI: https://doi.org/10.4049/jimmunol.1200861
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    Multiple Redundant Effector Mechanisms of CD8+ T Cells Protect against Influenza Infection
    Hiromasa Hamada, Elizabeth Bassity, Amanda Flies, Tara M. Strutt, Maria de Luz Garcia-Hernandez, K. Kai McKinstry, Tie Zou, Susan L. Swain and Richard W. Dutton
    J Immunol January 1, 2013, 190 (1) 296-306; DOI: https://doi.org/10.4049/jimmunol.1200571
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    Complete Dependence on IRAK4 Kinase Activity in TLR2, but Not TLR4, Signaling Pathways Underlies Decreased Cytokine Production and Increased Susceptibility to Streptococcus pneumoniae Infection in IRAK4 Kinase–Inactive Mice
    Meghan E. Pennini, Darren J. Perkins, Andres M. Salazar, Michael Lipsky and Stefanie N. Vogel
    J Immunol January 1, 2013, 190 (1) 307-316; DOI: https://doi.org/10.4049/jimmunol.1201644
  • Open Access
    Antibody Binding to Cryptococcus neoformans Impairs Budding by Altering Capsular Mechanical Properties

    Author Choice Article

    Radames J. B. Cordero, Bruno Pontes, Susana Frases, Antonio S. Nakouzi, Leonardo Nimrichter, Marcio L. Rodrigues, Nathan B. Viana and Arturo Casadevall
    J Immunol January 1, 2013, 190 (1) 317-323; DOI: https://doi.org/10.4049/jimmunol.1202324

INNATE IMMUNITY AND INFLAMMATION

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    Gαi2 Is the Essential Gαi Protein in Immune Complex–Induced Lung Disease
    Kristina Wiege, Syed R. Ali, Britta Gewecke, Ana Novakovic, Franziska M. Konrad, Katja Pexa, Sandra Beer-Hammer, Jörg Reutershan, Roland P. Piekorz, Reinhold E. Schmidt, Bernd Nürnberg and J. Engelbert Gessner
    J Immunol January 1, 2013, 190 (1) 324-333; DOI: https://doi.org/10.4049/jimmunol.1201398
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    TLR Agonists Stimulate Nlrp3-Dependent IL-1β Production Independently of the Purinergic P2X7 Receptor in Dendritic Cells and In Vivo
    Yuan He, Luigi Franchi and Gabriel Núñez
    J Immunol January 1, 2013, 190 (1) 334-339; DOI: https://doi.org/10.4049/jimmunol.1202737
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    FcγRIIb on Myeloid Cells and Intrinsic Renal Cells Rather than B Cells Protects from Nephrotoxic Nephritis
    Phoebe E. H. Sharp, Javier Martin-Ramirez, Sara M. Mangsbo, Peter Boross, Charles D. Pusey, Ivo P. Touw, H. Terence Cook, J. Sjef Verbeek and Ruth M. Tarzi
    J Immunol January 1, 2013, 190 (1) 340-348; DOI: https://doi.org/10.4049/jimmunol.1202250
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    TLR9-Dependent IL-23/IL-17 Is Required for the Generation of Stachybotrys chartarum–Induced Hypersensitivity Pneumonitis
    Urvashi Bhan, Michael J. Newstead, Xianying Zeng, Amy Podsaid, Moloy Goswami, Megan N. Ballinger, Steven L. Kunkel and Theodore J. Standiford
    J Immunol January 1, 2013, 190 (1) 349-356; DOI: https://doi.org/10.4049/jimmunol.1202225
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    Phosphatidylinositol 3-Kinase-γ Signaling Promotes Campylobacter jejuni–Induced Colitis through Neutrophil Recruitment in Mice
    Xiaolun Sun, Bo Liu, Ryan Balfour Sartor and Christian Jobin
    J Immunol January 1, 2013, 190 (1) 357-365; DOI: https://doi.org/10.4049/jimmunol.1201825
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    Dermatophagoides pteronyssinus Major Allergen 1 Activates the Innate Immune Response of the Fruit Fly Drosophila melanogaster
    Christine Warmbold, Karin Uliczka, Fiorentina Rus, Roland Suck, Arnd Petersen, Neal Silverman, Artur J. Ulmer, Holger Heine and Thomas Roeder
    J Immunol January 1, 2013, 190 (1) 366-371; DOI: https://doi.org/10.4049/jimmunol.1201347
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    AMP-Activated Protein Kinase Restricts IFN-γ Signaling
    Gordon P. Meares, Hongwei Qin, Yudong Liu, Andrew T. Holdbrooks and Etty N. Benveniste
    J Immunol January 1, 2013, 190 (1) 372-380; DOI: https://doi.org/10.4049/jimmunol.1202390
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    Phosphoinositide 3-OH Kinase Regulates Integrin-Dependent Processes in Neutrophils by Signaling through Its Effector ARAP3
    Laure Gambardella, Karen E. Anderson, Zoltán Jakus, Miklós Kovács, Susann Voigt, Phillip T. Hawkins, Len Stephens, Attila Mócsai and Sonja Vermeren
    J Immunol January 1, 2013, 190 (1) 381-391; DOI: https://doi.org/10.4049/jimmunol.1201330
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    Central Role for Endothelial Human Deneddylase-1/SENP8 in Fine-Tuning the Vascular Inflammatory Response
    Stefan F. Ehrentraut, Douglas J. Kominsky, Louise E. Glover, Eric L. Campbell, Caleb J. Kelly, Brittelle E. Bowers, Amanda J. Bayless and Sean P. Colgan
    J Immunol January 1, 2013, 190 (1) 392-400; DOI: https://doi.org/10.4049/jimmunol.1202041
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    In Vivo Processing of CXCL5 (LIX) by Matrix Metalloproteinase (MMP)-2 and MMP-9 Promotes Early Neutrophil Recruitment in IL-1β–Induced Peritonitis
    Jian Song, Chuan Wu, Xueli Zhang and Lydia M. Sorokin
    J Immunol January 1, 2013, 190 (1) 401-410; DOI: https://doi.org/10.4049/jimmunol.1202286
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    CD47 Deficiency Does Not Impede Polymorphonuclear Neutrophil Transmigration but Attenuates Granulopoiesis at the Postacute Stage of Colitis
    Zhen Bian, YaLan Guo, Youqun Luo, Alexandra Tremblay, Xiugen Zhang, Sanam Dharma, Aarti Mishra and Yuan Liu
    J Immunol January 1, 2013, 190 (1) 411-417; DOI: https://doi.org/10.4049/jimmunol.1201963
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    TLR3, TRIF, and Caspase 8 Determine Double-Stranded RNA-Induced Epithelial Cell Death and Survival In Vivo
    Christopher S. McAllister, Omar Lakhdari, Guillaume Pineton de Chambrun, Mélanie G. Gareau, Alexis Broquet, Gin Hyug Lee, Steven Shenouda, Lars Eckmann and Martin F. Kagnoff
    J Immunol January 1, 2013, 190 (1) 418-427; DOI: https://doi.org/10.4049/jimmunol.1202756

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    GATA-3 Regulates the Homeostasis and Activation of CD8+ T Cells
    Tzong-Shyuan Tai, Sung-Yun Pai and I-Cheng Ho
    J Immunol January 1, 2013, 190 (1) 428-437; DOI: https://doi.org/10.4049/jimmunol.1201361
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    YKL-40 Induces IL-8 Expression from Bronchial Epithelium via MAPK (JNK and ERK) and NF-κB Pathways, Causing Bronchial Smooth Muscle Proliferation and Migration
    Hao Tang, Yu Sun, Zhaoquan Shi, Hai Huang, Zheng Fang, Jiquan Chen, Qingyu Xiu and Bing Li
    J Immunol January 1, 2013, 190 (1) 438-446; DOI: https://doi.org/10.4049/jimmunol.1201827

TRANSPLANTATION

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    Unraveling Graft-versus-Host Disease and Graft-versus-Leukemia Responses Using TCR Vβ Spectratype Analysis in a Murine Bone Marrow Transplantation Model
    Stacey L. Fanning, Jenny Zilberberg, Johann Stein, Kristin Vazzana, Stephanie A. Berger, Robert Korngold and Thea M. Friedman
    J Immunol January 1, 2013, 190 (1) 447-457; DOI: https://doi.org/10.4049/jimmunol.1201641
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    Adenosine A2A Receptor Agonist–Mediated Increase in Donor-Derived Regulatory T Cells Suppresses Development of Graft-versus-Host Disease
    Kyu Lee Han, Stephenie V. M. Thomas, Sherry M. Koontz, Cattlena M. Changpriroa, Seung-Kwon Ha, Harry L. Malech and Elizabeth M. Kang
    J Immunol January 1, 2013, 190 (1) 458-468; DOI: https://doi.org/10.4049/jimmunol.1201325

TUMOR IMMUNOLOGY

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    Immune-Mediated Regression of Established B16F10 Melanoma by Intratumoral Injection of Attenuated Toxoplasma gondii Protects against Rechallenge
    Jason R. Baird, Katelyn T. Byrne, Patrick H. Lizotte, Seiko Toraya-Brown, Uciane K. Scarlett, Matthew P. Alexander, Mee Rie Sheen, Barbara A. Fox, David J. Bzik, Marcus Bosenberg, David W. Mullins, Mary Jo Turk and Steven Fiering
    J Immunol January 1, 2013, 190 (1) 469-478; DOI: https://doi.org/10.4049/jimmunol.1201209
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    Enzymatic Discovery of a HER-2/neu Epitope That Generates Cross-Reactive T Cells
    Andrea M. Henle, Courtney L. Erskine, Linda M. Benson, Raphael Clynes and Keith L. Knutson
    J Immunol January 1, 2013, 190 (1) 479-488; DOI: https://doi.org/10.4049/jimmunol.1201264
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    Effective Cooperation of Monoclonal Antibody and Peptide Vaccine for the Treatment of Mouse Melanoma
    Long V. Ly, Marjolein Sluijter, Sjoerd H. van der Burg, Martine J. Jager and Thorbald van Hall
    J Immunol January 1, 2013, 190 (1) 489-496; DOI: https://doi.org/10.4049/jimmunol.1200135
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The Journal of Immunology: 190 (1)
The Journal of Immunology
Vol. 190, Issue 1
1 Jan 2013
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  • IN THIS ISSUE
  • PILLARS OF IMMUNOLOGY
  • CUTTING EDGE
  • ANTIGEN RECOGNITION AND RESPONSES
  • AUTOIMMUNITY
  • CLINICAL AND HUMAN IMMUNOLOGY
  • IMMUNE REGULATION
  • IMMUNOGENETICS
  • IMMUNOTHERAPY AND VACCINES
  • INFECTIOUS DISEASE AND HOST RESPONSE
  • INNATE IMMUNITY AND INFLAMMATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • TRANSPLANTATION
  • TUMOR IMMUNOLOGY
  • Highlights
  • Most Cited
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606