The Journal of Immunology: 188 (12)

June 15, 2012; Volume 188,Issue 12

IN THIS ISSUE

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In This Issue
J Immunol June 15, 2012, 188 (12) 5807-5808; DOI: https://doi.org/10.4049/jimmunol.1290026

LETTERS TO THE EDITOR

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Comment on “CD4⁺CD8⁺ T Cells Represent a Significant Portion of the Anti-HIV T Cell Response to Acute HIV Infection”
Lena Al-Harthi

J Immunol June 15, 2012, 188 (12) 5809; DOI: https://doi.org/10.4049/jimmunol.1290028
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Response to Comment on “CD4⁺CD8⁺ T Cells Represent a Significant Portion of the Anti-HIV T Cell Response to Acute HIV Infection”
Marc A. Frahm, Georgia D. Tomaras and Guido Ferrari

J Immunol June 15, 2012, 188 (12) 5809-5810; DOI: https://doi.org/10.4049/jimmunol.1290029

BRIEF REVIEWS

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Hidden Memories: Frontline Memory T Cells and Early Pathogen Interception
David Masopust and Louis J. Picker

J Immunol June 15, 2012, 188 (12) 5811-5817; DOI: https://doi.org/10.4049/jimmunol.1102695

CUTTING EDGE

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Cutting Edge: Evidence for a Dynamically Driven T Cell Signaling Mechanism
William F. Hawse, Matthew M. Champion, Michelle V. Joyce, Lance M. Hellman, Moushumi Hossain, Veronica Ryan, Brian G. Pierce, Zhiping Weng and Brian M. Baker

J Immunol June 15, 2012, 188 (12) 5819-5823; DOI: https://doi.org/10.4049/jimmunol.1200952
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Cutting Edge: LPS-Induced Emergency Myelopoiesis Depends on TLR4-Expressing Nonhematopoietic Cells
Steffen Boettcher, Patrick Ziegler, Michael A. Schmid, Hitoshi Takizawa, Nico van Rooijen, Manfred Kopf, Mathias Heikenwalder and Markus G. Manz

J Immunol June 15, 2012, 188 (12) 5824-5828; DOI: https://doi.org/10.4049/jimmunol.1103253
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Cutting Edge: Slamf8 Is a Negative Regulator of Nox2 Activity in Macrophages
Guoxing Wang, Ana C. Abadía-Molina, Scott B. Berger, Xavier Romero, Michael S. O’Keeffe, Domingo I. Rojas-Barros, Marta Aleman, Gongxian Liao, Elena Maganto-García, Manuel Fresno, Ninghai Wang, Cynthia Detre and Cox Terhorst

J Immunol June 15, 2012, 188 (12) 5829-5832; DOI: https://doi.org/10.4049/jimmunol.1102620
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Cutting Edge: Divergent Cell-Specific Functions of MyD88 for Inflammatory Responses and Organ Injury in Septic Peritonitis
Petra Gais, Daniel Reim, Gabriela Jusek, Tanja Rossmann-Bloeck, Heike Weighardt, Klaus Pfeffer, Felicitas Altmayr, Klaus-Peter Janssen and Bernhard Holzmann

J Immunol June 15, 2012, 188 (12) 5833-5837; DOI: https://doi.org/10.4049/jimmunol.1200038

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Amino-Terminal Extended Peptide Single-Chain Trimers Are Potent Synthetic Agonists for Memory Human CD8⁺ T Cells
Beatriz M. Carreno, Michelle Becker-Hapak, Megan Chan, Wen-Rong Lie, Xiaoli Wang, Ted H. Hansen and Gerald P. Linette

J Immunol June 15, 2012, 188 (12) 5839-5849; DOI: https://doi.org/10.4049/jimmunol.1103647
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NK Cell Tolerance to TLR Agonists Mediated by Regulatory T Cells after Polymicrobial Sepsis
Fernando Souza-Fonseca-Guimaraes, Marianna Parlato, Catherine Fitting, Jean-Marc Cavaillon and Minou Adib-Conquy

J Immunol June 15, 2012, 188 (12) 5850-5858; DOI: https://doi.org/10.4049/jimmunol.1103616
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An In Vivo IL-7 Requirement for Peripheral Foxp3⁺ Regulatory T Cell Homeostasis
Grace Y. Kim, Davinna L. Ligons, Changwan Hong, Megan A. Luckey, Hilary R. Keller, Xuguang Tai, Philip J. Lucas, Ronald E. Gress and Jung-Hyun Park

J Immunol June 15, 2012, 188 (12) 5859-5866; DOI: https://doi.org/10.4049/jimmunol.1102328
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Decoy Receptor 3 Suppresses TLR2-Mediated B Cell Activation by Targeting NF-κB
Zi-Ming Huang, Jhi-Kai Kang, Chih-Yu Chen, Tz-Hau Tseng, Chien-Wen Chang, Yung-Chi Chang, Shyh-Kuan Tai, Shie-Liang Hsieh and Chuen-Miin Leu

J Immunol June 15, 2012, 188 (12) 5867-5876; DOI: https://doi.org/10.4049/jimmunol.1102516
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Kv1.3 Deletion Biases T Cells toward an Immunoregulatory Phenotype and Renders Mice Resistant to Autoimmune Encephalomyelitis
Anne R. Gocke, Lori A. Lebson, Inna V. Grishkan, Lina Hu, Hai M. Nguyen, Katharine A. Whartenby, K. George Chandy and Peter A. Calabresi

J Immunol June 15, 2012, 188 (12) 5877-5886; DOI: https://doi.org/10.4049/jimmunol.1103095
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Protein Kinase C-θ Promotes Th17 Differentiation via Upregulation of Stat3
Myung-Ja Kwon, Jian Ma, Yan Ding, Ruiqing Wang and Zuoming Sun

J Immunol June 15, 2012, 188 (12) 5887-5897; DOI: https://doi.org/10.4049/jimmunol.1102941
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Innate IFNs and Plasmacytoid Dendritic Cells Constrain Th2 Cytokine Responses to Rhinovirus: A Regulatory Mechanism with Relevance to Asthma
Antonia L. Pritchard, Melanie L. Carroll, Julie G. Burel, Olivia J. White, Simon Phipps and John W. Upham

J Immunol June 15, 2012, 188 (12) 5898-5905; DOI: https://doi.org/10.4049/jimmunol.1103507
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CIKS/Act1-Mediated Signaling by IL-17 Cytokines in Context: Implications for How a CIKS Gene Variant May Predispose to Psoriasis
Søren Ulrik Sønder, Andrea Paun, Hye-Lin Ha, Peter F. Johnson and Ulrich Siebenlist

J Immunol June 15, 2012, 188 (12) 5906-5914; DOI: https://doi.org/10.4049/jimmunol.1103233
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IL-15–Dependent Upregulation of GITR on CD8 Memory Phenotype T Cells in the Bone Marrow Relative to Spleen and Lymph Node Suggests the Bone Marrow as a Site of Superior Bioavailability of IL-15
Laura M. Snell, Gloria H. Y. Lin and Tania H. Watts

J Immunol June 15, 2012, 188 (12) 5915-5923; DOI: https://doi.org/10.4049/jimmunol.1103270
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Aminopeptidase Substrate Preference Affects HIV Epitope Presentation and Predicts Immune Escape Patterns in HIV-Infected Individuals
Shao Chong Zhang, Eric Martin, Mariko Shimada, Sasha Blue Godfrey, Jennifer Fricke, Shirley Locastro, Nicole Y. Lai, Paul Liebesny, Jonathan M. Carlson, Chanson J. Brumme, Oluwatobi Awele Ogbechie, Huabiao Chen, Bruce D. Walker, Zabrina L. Brumme, Daniel G. Kavanagh and Sylvie Le Gall

J Immunol June 15, 2012, 188 (12) 5924-5934; DOI: https://doi.org/10.4049/jimmunol.1200219
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Pten Loss in CD4 T Cells Enhances Their Helper Function but Does Not Lead to Autoimmunity or Lymphoma
Dalya R. Soond, Fabien Garçon, Daniel T. Patton, Julia Rolf, Martin Turner, Cheryl Scudamore, Oliver A. Garden and Klaus Okkenhaug

J Immunol June 15, 2012, 188 (12) 5935-5943; DOI: https://doi.org/10.4049/jimmunol.1102116
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CD23⁺CD21^highCD1d^high B Cells in Inflamed Lymph Nodes Are a Locally Differentiated Population with Increased Antigen Capture and Activation Potential
Safiehkhatoon Moshkani, Igor I. Kuzin, Funmilola Adewale, Johan Jansson, Iñaki Sanz, Edward M. Schwarz and Andrea Bottaro

J Immunol June 15, 2012, 188 (12) 5944-5953; DOI: https://doi.org/10.4049/jimmunol.1103071
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Activated T Cell Exosomes Promote Tumor Invasion via Fas Signaling Pathway
Zhijian Cai, Fei Yang, Lei Yu, Zhou Yu, Lingling Jiang, Qingqing Wang, Yunshan Yang, Lie Wang, Xuetao Cao and Jianli Wang

J Immunol June 15, 2012, 188 (12) 5954-5961; DOI: https://doi.org/10.4049/jimmunol.1103466
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Immunological Disruption of Antiangiogenic Signals by Recruited Allospecific T Cells Leads to Corneal Allograft Rejection
Yaohong Tan, Fernando Cruz-Guilloty, Carlos A. Medina-Mendez, Nicholas J. Cutrufello, Rosa E. Martinez, Maitee Urbieta, David Wilson, Yiwen Li and Victor L. Perez

J Immunol June 15, 2012, 188 (12) 5962-5969; DOI: https://doi.org/10.4049/jimmunol.1103216
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Megakaryocyte Progenitors Are the Main APCs Inducing Th17 Response to Lupus Autoantigens and Foreign Antigens
Hee-Kap Kang, Ming-Yi Chiang, Diane Ecklund, Li Zhang, Rosalind Ramsey-Goldman and Syamal K. Datta

J Immunol June 15, 2012, 188 (12) 5970-5980; DOI: https://doi.org/10.4049/jimmunol.1200452
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Lipopolysaccharide-Activated Dendritic Cells: “Exhausted” or Alert and Waiting?
Kaveh Abdi, Nevil J. Singh and Polly Matzinger

J Immunol June 15, 2012, 188 (12) 5981-5989; DOI: https://doi.org/10.4049/jimmunol.1102868
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High DGK-α and Disabled MAPK Pathways Cause Dysfunction of Human Tumor-Infiltrating CD8⁺ T Cells That Is Reversible by Pharmacologic Intervention
Petra U. Prinz, Anna N. Mendler, Ilias Masouris, Leopold Durner, Ralph Oberneder and Elfriede Noessner

J Immunol June 15, 2012, 188 (12) 5990-6000; DOI: https://doi.org/10.4049/jimmunol.1103028
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A Switch in Pathogenic Mechanism in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis in IFN-γ–Inducible Lysosomal Thiol Reductase-Free Mice
Cheryl M. Bergman, Cecilia B. Marta, Maja Maric, Steven E. Pfeiffer, Peter Cresswell and Nancy H. Ruddle

J Immunol June 15, 2012, 188 (12) 6001-6009; DOI: https://doi.org/10.4049/jimmunol.1101898
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The Non-Ig Parts of the VpreB and λ5 Proteins of the Surrogate Light Chain Play Opposite Roles in the Surface Representation of the Precursor B Cell Receptor
Marko Knoll, Yuki Yanagisawa, Szandor Simmons, Niklas Engels, Jürgen Wienands, Fritz Melchers and Kazuo Ohnishi

J Immunol June 15, 2012, 188 (12) 6010-6017; DOI: https://doi.org/10.4049/jimmunol.1200071
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BLyS-Mediated Modulation of Naive B Cell Subsets Impacts HIV Env-Induced Antibody Responses
Pia Dosenovic, Martina Soldemo, Jean L. Scholz, Sijy O’Dell, Emilie K. Grasset, Nadège Pelletier, Mikael C. I. Karlsson, John R. Mascola, Richard T. Wyatt, Michael P. Cancro and Gunilla B. Karlsson Hedestam

J Immunol June 15, 2012, 188 (12) 6018-6026; DOI: https://doi.org/10.4049/jimmunol.1200466
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The Skin, a Novel Niche for Recirculating B Cells
Skye A. Geherin, Sarah R. Fintushel, Michael H. Lee, R. Paul Wilson, Reema T. Patel, Carsten Alt, Alan J. Young, John B. Hay and Gudrun F. Debes

J Immunol June 15, 2012, 188 (12) 6027-6035; DOI: https://doi.org/10.4049/jimmunol.1102639
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HIV-1 Capture and Antigen Presentation by Dendritic Cells: Enhanced Viral Capture Does Not Correlate with Better T Cell Activation
Maria T. Rodriguez-Plata, Alejandra Urrutia, Sylvain Cardinaud, Maria J. Buzón, Nuria Izquierdo-Useros, Julia G. Prado, Maria C. Puertas, Itziar Erkizia, Pierre-Grégoire Coulon, Samandhy Cedeño, Bonaventura Clotet, Arnaud Moris and Javier Martinez-Picado

J Immunol June 15, 2012, 188 (12) 6036-6045; DOI: https://doi.org/10.4049/jimmunol.1200267
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MAPK Regulation of IL-4/IL-13 Receptors Contributes to the Synergistic Increase in CCL11/Eotaxin-1 in Response to TGF-β1 and IL-13 in Human Airway Fibroblasts
Xiuxia Zhou, Haizhen Hu, Silvana Balzar, John B. Trudeau and Sally E. Wenzel

J Immunol June 15, 2012, 188 (12) 6046-6054; DOI: https://doi.org/10.4049/jimmunol.1102760
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Human CCR4⁺CCR6⁺Th17 Cells Suppress Autologous CD8⁺ T Cell Responses
Fei Zhao, Bastian Hoechst, Jaba Gamrekelashvili, Lars A. Ormandy, Torsten Voigtländer, Heiner Wedemeyer, Kris Ylaya, Xin Wei Wang, Stephen M. Hewitt, Michael P. Manns, Firouzeh Korangy and Tim F. Greten

J Immunol June 15, 2012, 188 (12) 6055-6062; DOI: https://doi.org/10.4049/jimmunol.1102918
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Differential Effects of Denileukin Diftitox IL-2 Immunotoxin on NK and Regulatory T Cells in Nonhuman Primates
Yohei Yamada, Akihiro Aoyama, Georges Tocco, Svjetlan Boskovic, Ognjenka Nadazdin, Alessandro Alessandrini, Joren C. Madsen, A. Benedict Cosimi, Gilles Benichou and Tatsuo Kawai

J Immunol June 15, 2012, 188 (12) 6063-6070; DOI: https://doi.org/10.4049/jimmunol.1200656
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Stromal Endothelial Cells Establish a Bidirectional Crosstalk with Chronic Lymphocytic Leukemia Cells through the TNF-Related Factors BAFF, APRIL, and CD40L
Montserrat Cols, Carolina M. Barra, Bing He, Irene Puga, Weifeng Xu, April Chiu, Wayne Tam, Daniel M. Knowles, Stacey R. Dillon, John P. Leonard, Richard R. Furman, Kang Chen and Andrea Cerutti

J Immunol June 15, 2012, 188 (12) 6071-6083; DOI: https://doi.org/10.4049/jimmunol.1102066
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IL-7 Functionally Segregates the Pro-B Cell Stage by Regulating Transcription of Recombination Mediators across Cell Cycle
Kristen Johnson, Julie Chaumeil, Mariann Micsinai, Joy M. H. Wang, Laura B. Ramsey, Gisele V. Baracho, Robert C. Rickert, Francesco Strino, Yuval Kluger, Michael A. Farrar and Jane A. Skok

J Immunol June 15, 2012, 188 (12) 6084-6092; DOI: https://doi.org/10.4049/jimmunol.1200368
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A p53 Axis Regulates B Cell Receptor-Triggered, Innate Immune System-Driven B Cell Clonal Expansion
Hyunjoo Lee, Shabirul Haque, Jennifer Nieto, Joshua Trott, John K. Inman, Steven McCormick, Nicholas Chiorazzi and Patricia K. A. Mongini

J Immunol June 15, 2012, 188 (12) 6093-6108; DOI: https://doi.org/10.4049/jimmunol.1103037
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Type I IFN Induced by Adenovirus Serotypes 28 and 35 Has Multiple Effects on T Cell Immunogenicity
Matthew J. Johnson, Constantinos Petrovas, Takuya Yamamoto, Ross W. B. Lindsay, Karin Loré, Jason G. D. Gall, Emma Gostick, François Lefebvre, Mark J. Cameron, David A. Price, Elias Haddad, Rafick-Pierre Sekaly, Robert A. Seder and Richard A. Koup

J Immunol June 15, 2012, 188 (12) 6109-6118; DOI: https://doi.org/10.4049/jimmunol.1103717
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15 kDa Granulysin Causes Differentiation of Monocytes to Dendritic Cells but Lacks Cytotoxic Activity
Carol Clayberger, Michael W. Finn, Tianhong Wang, Reena Saini, Christine Wilson, Valarie A. Barr, Marianna Sabatino, Luciano Castiello, David Stroncek and Alan M. Krensky

J Immunol June 15, 2012, 188 (12) 6119-6126; DOI: https://doi.org/10.4049/jimmunol.1200570
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B Cell Receptor-ERK1/2 Signal Cancels PAX5-Dependent Repression of BLIMP1 through PAX5 Phosphorylation: A Mechanism of Antigen-Triggering Plasma Cell Differentiation
Takahiko Yasuda, Fumihiko Hayakawa, Shingo Kurahashi, Keiki Sugimoto, Yosuke Minami, Akihiro Tomita and Tomoki Naoe

J Immunol June 15, 2012, 188 (12) 6127-6134; DOI: https://doi.org/10.4049/jimmunol.1103039
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The Cytoskeletal Adaptor Protein IQGAP1 Regulates TCR-Mediated Signaling and Filamentous Actin Dynamics
Jacquelyn A. Gorman, Alexander Babich, Christopher J. Dick, Renee A. Schoon, Alexander Koenig, Timothy S. Gomez, Janis K. Burkhardt and Daniel D. Billadeau

J Immunol June 15, 2012, 188 (12) 6135-6144; DOI: https://doi.org/10.4049/jimmunol.1103487
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Development of Mature and Functional Human Myeloid Subsets in Hematopoietic Stem Cell-Engrafted NOD/SCID/IL2rγKO Mice
Satoshi Tanaka, Yoriko Saito, Jun Kunisawa, Yosuke Kurashima, Taichi Wake, Nahoko Suzuki, Leonard D. Shultz, Hiroshi Kiyono and Fumihiko Ishikawa

J Immunol June 15, 2012, 188 (12) 6145-6155; DOI: https://doi.org/10.4049/jimmunol.1103660
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Augmented IL-15Rα Expression by CD40 Activation Is Critical in Synergistic CD8 T Cell-Mediated Antitumor Activity of Anti-CD40 Antibody with IL-15 in TRAMP-C2 Tumors in Mice
Meili Zhang, Wei Ju, Zhengsheng Yao, Ping Yu, Bih-Rong Wei, R. Mark Simpson, Rebecca Waitz, Marcella Fassò, James P. Allison and Thomas A. Waldmann

J Immunol June 15, 2012, 188 (12) 6156-6164; DOI: https://doi.org/10.4049/jimmunol.1102604

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Dimerization of NKp46 Receptor Is Essential for NKp46-Mediated Lysis: Characterization of the Dimerization Site by Epitope Mapping
Michal Jaron-Mendelson, Rami Yossef, Michael Y. Appel, Alon Zilka, Uzi Hadad, Fabian Afergan, Benyamin Rosental, Stanislav Engel, Shlomo Nedvetzki, Alex Braiman and Angel Porgador

J Immunol June 15, 2012, 188 (12) 6165-6174; DOI: https://doi.org/10.4049/jimmunol.1102496
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Negative Feedback Regulation of Antigen Receptors through Calmodulin Inhibition of E2A
Jiyoti Verma-Gaur, Jannek Hauser and Thomas Grundström

J Immunol June 15, 2012, 188 (12) 6175-6183; DOI: https://doi.org/10.4049/jimmunol.1103105
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HLA-B27 Homodimers and Free H Chains Are Stronger Ligands for Leukocyte Ig-like Receptor B2 than Classical HLA Class I
Joanna Giles, Jackie Shaw, Christopher Piper, Isabel Wong-Baeza, Kirsty McHugh, Anna Ridley, Demin Li, Izabela Lenart, Antony N. Antoniou, Katilin DiGleria, Kimiko Kuroki, Katsumi Maenaka, Paul Bowness and Simon Kollnberger

J Immunol June 15, 2012, 188 (12) 6184-6193; DOI: https://doi.org/10.4049/jimmunol.1102711
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Signal-Transducing Adaptor Protein-2 Modulates Fas-Mediated T Cell Apoptosis by Interacting with Caspase-8
Yuichi Sekine, Chikako Yamamoto, Michinori Kakisaka, Ryuta Muromoto, Shigeyuki Kon, Dai Ashitomi, Natsuko Fujita, Akihiko Yoshimura, Kenji Oritani and Tadashi Matsuda

J Immunol June 15, 2012, 188 (12) 6194-6204; DOI: https://doi.org/10.4049/jimmunol.1103467

HOST DEFENSE

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Dynamic Roles of Type I and Type II IFNs in Early Infection with Mycobacterium tuberculosis
Ludovic Desvignes, Andrea J. Wolf and Joel D. Ernst

J Immunol June 15, 2012, 188 (12) 6205-6215; DOI: https://doi.org/10.4049/jimmunol.1200255
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Contact-Dependent Interference with Invariant NKT Cell Activation by Herpes Simplex Virus-Infected Cells
Lidija Bosnjak, Peter Sahlström, Dominic Paquin-Proulx, Edwin Leeansyah, Markus Moll and Johan K. Sandberg

J Immunol June 15, 2012, 188 (12) 6216-6224; DOI: https://doi.org/10.4049/jimmunol.1100218
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Passive Immunoprotection of Plasmodium falciparum-Infected Mice Designates the CyRPA as Candidate Malaria Vaccine Antigen
Anita M. Dreyer, Hugues Matile, Petros Papastogiannidis, Jolanda Kamber, Paola Favuzza, Till S. Voss, Sergio Wittlin and Gerd Pluschke

J Immunol June 15, 2012, 188 (12) 6225-6237; DOI: https://doi.org/10.4049/jimmunol.1103177
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Differential Regulation of the Let-7 Family of MicroRNAs in CD4⁺ T Cells Alters IL-10 Expression
Sanjay Swaminathan, Kazuo Suzuki, Nabila Seddiki, Warren Kaplan, Mark J. Cowley, Chantelle L. Hood, Jennifer L. Clancy, Daniel D. Murray, Catalina Méndez, Linda Gelgor, Ben Anderson, Norman Roth, David A. Cooper and Anthony D. Kelleher

J Immunol June 15, 2012, 188 (12) 6238-6246; DOI: https://doi.org/10.4049/jimmunol.1101196
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Herpes Simplex Virus Type 2 Infection of Human Epithelial Cells Induces CXCL9 Expression and CD4⁺ T Cell Migration via Activation of p38-CCAAT/Enhancer-Binding Protein-β Pathway
Wenjie Huang, Kai Hu, Sukun Luo, Mudan Zhang, Chang Li, Wei Jin, Yalan Liu, George E. Griffin, Robin J. Shattock and Qinxue Hu

J Immunol June 15, 2012, 188 (12) 6247-6257; DOI: https://doi.org/10.4049/jimmunol.1103706
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Loss of TNF Signaling Facilitates the Development of a Novel Ly-6C^low Macrophage Population Permissive for Leishmania major Infection
Phillip D. Fromm, Jessica Kling, Matthias Mack, Jonathon D. Sedgwick and Heinrich Körner

J Immunol June 15, 2012, 188 (12) 6258-6266; DOI: https://doi.org/10.4049/jimmunol.1100977

INFLAMMATION

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Transplanted Mesoangioblasts Require Macrophage IL-10 for Survival in a Mouse Model of Muscle Injury
Lidia Bosurgi, Gianfranca Corna, Michela Vezzoli, Thierry Touvier, Giulio Cossu, Angelo A. Manfredi, Silvia Brunelli and Patrizia Rovere-Querini

J Immunol June 15, 2012, 188 (12) 6267-6277; DOI: https://doi.org/10.4049/jimmunol.1102680
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The Transcription Factor Zeb2 Regulates Signaling in Mast Cells
Emilia Alina Barbu, Juan Zhang, Elsa H. Berenstein, Jacqueline R. Groves, Lauren M. Parks and Reuben P. Siraganian

J Immunol June 15, 2012, 188 (12) 6278-6286; DOI: https://doi.org/10.4049/jimmunol.1102660
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IL-17 and TNF-α Sustain Neutrophil Recruitment during Inflammation through Synergistic Effects on Endothelial Activation
Gabriel K. Griffin, Gail Newton, Margarite L. Tarrio, De-xiu Bu, Elena Maganto-Garcia, Veronica Azcutia, Pilar Alcaide, Nir Grabie, Francis W. Luscinskas, Kevin J. Croce and Andrew H. Lichtman

J Immunol June 15, 2012, 188 (12) 6287-6299; DOI: https://doi.org/10.4049/jimmunol.1200385
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Leukemia Inhibitory Factor Signaling Is Required for Lung Protection during Pneumonia
Lee J. Quinton, Joseph P. Mizgerd, Kristie L. Hilliard, Matthew R. Jones, Candice Y. Kwon and Eri Allen

J Immunol June 15, 2012, 188 (12) 6300-6308; DOI: https://doi.org/10.4049/jimmunol.1200256
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Complement-Dependent Injury and Protection in a Murine Model of Acute Dextran Sulfate Sodium-Induced Colitis
Jennifer Schepp-Berglind, Carl Atkinson, Michelle Elvington, Fei Qiao, Peter Mannon and Stephen Tomlinson

J Immunol June 15, 2012, 188 (12) 6309-6318; DOI: https://doi.org/10.4049/jimmunol.1200553
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Enhanced Anti-Serpin Antibody Activity Inhibits Autoimmune Inflammation in Type 1 Diabetes
Jan Czyzyk, Octavian Henegariu, Paula Preston-Hurlburt, Raman Baldzizhar, Christine Fedorchuk, Enric Esplugues, Kim Bottomly, Frans K. Gorus, Kevan Herold and Richard A. Flavell

J Immunol June 15, 2012, 188 (12) 6319-6327; DOI: https://doi.org/10.4049/jimmunol.1200467
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Monocytic Thrombomodulin Triggers LPS- and Gram-Negative Bacteria-Induced Inflammatory Response
Chih-Yuan Ma, Guey-Yueh Shi, Chung-Sheng Shi, Yuan-Chung Kao, Shu-Wha Lin and Hua-Lin Wu

J Immunol June 15, 2012, 188 (12) 6328-6337; DOI: https://doi.org/10.4049/jimmunol.1102266
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Magnesium Decreases Inflammatory Cytokine Production: A Novel Innate Immunomodulatory Mechanism
Jun Sugimoto, Andrea M. Romani, Alice M. Valentin-Torres, Angel A. Luciano, Christina M. Ramirez Kitchen, Nicholas Funderburg, Sam Mesiano and Helene B. Bernstein

J Immunol June 15, 2012, 188 (12) 6338-6346; DOI: https://doi.org/10.4049/jimmunol.1101765
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RGS16 Attenuates Pulmonary Th2/Th17 Inflammatory Responses
Sucharita P. Shankar, Mark S. Wilson, Jeffrey A. DiVietro, Margaret M. Mentink-Kane, Zhihui Xie, Thomas A. Wynn and Kirk M. Druey

J Immunol June 15, 2012, 188 (12) 6347-6356; DOI: https://doi.org/10.4049/jimmunol.1103781
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L-Plastin Regulates Polarization and Migration in Chemokine-Stimulated Human T Lymphocytes
Michael Freeley, Francis O’Dowd, Toby Paul, Dmitry Kashanin, Anthony Davies, Dermot Kelleher and Aideen Long

J Immunol June 15, 2012, 188 (12) 6357-6370; DOI: https://doi.org/10.4049/jimmunol.1103242
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EVI1 Acts as an Inducible Negative-Feedback Regulator of NF-κB by Inhibiting p65 Acetylation
Xiangbin Xu, Chang-Hoon Woo, Rachel R. Steere, Byung Cheol Lee, Yuxian Huang, Jing Wu, Jinjiang Pang, Jae Hyang Lim, Haidong Xu, Wenhong Zhang, Anuhya S. Konduru, Chen Yan, Michael T. Cheeseman, Steve D. M. Brown and Jian-Dong Li

J Immunol June 15, 2012, 188 (12) 6371-6380; DOI: https://doi.org/10.4049/jimmunol.1103527
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Identification of TLT2 as an Engulfment Receptor for Apoptotic Cells
Andressa de Freitas, Sami Banerjee, Na Xie, Huachun Cui, Kasey I. Davis, Arnaud Friggeri, Mingui Fu, Edward Abraham and Gang Liu

J Immunol June 15, 2012, 188 (12) 6381-6388; DOI: https://doi.org/10.4049/jimmunol.1200020

CLINICAL IMMUNOLOGY

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Chimeric Antigen Receptor T Cells Shape Myeloid Cell Function within the Tumor Microenvironment through IFN-γ and GM-CSF
Paul Spear, Amorette Barber, Agnieszka Rynda-Apple and Charles L. Sentman

J Immunol June 15, 2012, 188 (12) 6389-6398; DOI: https://doi.org/10.4049/jimmunol.1103019
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CXCL17 Is a Mucosal Chemokine Elevated in Idiopathic Pulmonary Fibrosis That Exhibits Broad Antimicrobial Activity
Amanda M. Burkhardt, Kenneth P. Tai, Juan P. Flores-Guiterrez, Natalia Vilches-Cisneros, Karishma Kamdar, Oralia Barbosa-Quintana, Ricardo Valle-Rios, Peter A. Hevezi, Joaquin Zuñiga, Moises Selman, André J. Ouellette and Albert Zlotnik

J Immunol June 15, 2012, 188 (12) 6399-6406; DOI: https://doi.org/10.4049/jimmunol.1102903
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Adjuvant-like Effect of Vaccinia Virus 14K Protein: A Case Study with Malaria Vaccine Based on the Circumsporozoite Protein
Aneesh Vijayan, Carmen E. Gómez, Diego A. Espinosa, Alan G. Goodman, Lucas Sanchez-Sampedro, Carlos Oscar S. Sorzano, Fidel Zavala and Mariano Esteban

J Immunol June 15, 2012, 188 (12) 6407-6417; DOI: https://doi.org/10.4049/jimmunol.1102492
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Humoral and Cellular Capsid-Specific Immune Responses to Adeno-Associated Virus Type 1 in Randomized Healthy Donors
Philippe Veron, Christian Leborgne, Virginie Monteilhet, Sylvie Boutin, Samia Martin, Philippe Moullier and Carole Masurier

J Immunol June 15, 2012, 188 (12) 6418-6424; DOI: https://doi.org/10.4049/jimmunol.1200620

CORRECTIONS

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Correction: Protection of nonself surfaces from complement attack by factor h-binding peptides: implications for therapeutic medicine
You-Qiang Wu, Hongchang Qu, Georgia Sfyroera, Apostolia Tzekou, Brian K. Kay, Bo Nilsson, Kristina Nilsson Ekdahl, Daniel Ricklin and John D. Lambris

J Immunol June 15, 2012, 188 (12) 6425; DOI: https://doi.org/10.4049/jimmunol.1290027

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IN THIS ISSUE

LETTERS TO THE EDITOR

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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