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The Journal of Immunology

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Table of Contents

June 1, 2012; Volume 188,Issue 11

IN THIS ISSUE

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    In This Issue
    J Immunol June 1, 2012, 188 (11) 5201-5202; DOI: https://doi.org/10.4049/jimmunol.1290025

LETTERS TO THE EDITOR

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    Comment on “Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways”
    Pushpa Pandiyan and Michael Lenardo
    J Immunol June 1, 2012, 188 (11) 5203-5204; DOI: https://doi.org/10.4049/jimmunol.1290023
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    Response to Comment on “Cutting Edge: Regulatory T Cells Do Not Mediate Suppression via Programmed Cell Death Pathways”
    Andrea L. Szymczak-Workman, Greg M. Delgoffe, Douglas R. Green and Dario A. A. Vignali
    J Immunol June 1, 2012, 188 (11) 5204-5205; DOI: https://doi.org/10.4049/jimmunol.1290024
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    Comment on “Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire”
    Stephanie Ascough, Rebecca J. Ingram, Gökhan Metan, Bernard Maillere, Mehmet Doganay, Yusuf Ozkul, Louise U. Kim, Les Ballie, Steven Moore, Theresa B. Huwar, Shiranee Sriskandan and Daniel M. Altmann
    J Immunol June 1, 2012, 188 (11) 5205-5206; DOI: https://doi.org/10.4049/jimmunol.1290018
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    Response to Comment on “Frequency of Epitope-Specific Naive CD4+ T Cells Correlates with Immunodominance in the Human Memory Repertoire”
    William W. Kwok and Eddie A. James
    J Immunol June 1, 2012, 188 (11) 5206; DOI: https://doi.org/10.4049/jimmunol.1290019

PILLARS OF IMMUNOLOGY

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    How Discovery of Toll-Mediated Innate Immunity in Drosophila Impacted Our Understanding of TLR Signaling (and Vice Versa)
    Stefanie N. Vogel
    J Immunol June 1, 2012, 188 (11) 5207-5209; DOI: https://doi.org/10.4049/jimmunol.1201050
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    Pillars Article: The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults. Cell. 1996. 86: 973-983
    Bruno Lemaitre, Emmanuelle Nicolas, Lydia Michaut, Jean-Marc Reichhart and Jules A. Hoffmann
    J Immunol June 1, 2012, 188 (11) 5210-5220;

CUTTING EDGE

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    Cutting Edge: In the Absence of Regulatory T Cells, a Unique Th Cell Population Expands and Leads to a Loss of B Cell Anergy
    Steven M. Leonardo, Jessica L. De Santis, Laurent P. Malherbe and Stephen B. Gauld
    J Immunol June 1, 2012, 188 (11) 5223-5226; DOI: https://doi.org/10.4049/jimmunol.1103731

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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    IL-27 Production and STAT3-Dependent Upregulation of B7-H1 Mediate Immune Regulatory Functions of Liver Plasmacytoid Dendritic Cells
    Benjamin M. Matta, Giorgio Raimondi, Brian R. Rosborough, Tina L. Sumpter and Angus W. Thomson
    J Immunol June 1, 2012, 188 (11) 5227-5237; DOI: https://doi.org/10.4049/jimmunol.1103382
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    Structurally Identical Capsular Polysaccharide Expressed by Intact Group B Streptococcus versus Streptococcus pneumoniae Elicits Distinct Murine Polysaccharide-Specific IgG Responses In Vivo
    Swadhinya Arjunaraja, Lawrence C. Paoletti and Clifford M. Snapper
    J Immunol June 1, 2012, 188 (11) 5238-5246; DOI: https://doi.org/10.4049/jimmunol.1200132
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    Fyn Promotes Th17 Differentiation by Regulating the Kinetics of RORγt and Foxp3 Expression
    Aki Ueda, Liang Zhou and Paul L. Stein
    J Immunol June 1, 2012, 188 (11) 5247-5256; DOI: https://doi.org/10.4049/jimmunol.1102241
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    Chronic Spinal Cord Injury Impairs Primary Antibody Responses but Spares Existing Humoral Immunity in Mice
    Michael A. Oropallo, Katherine S. Held, Radhika Goenka, Sifat A. Ahmad, Patrick J. O’Neill, Oswald Steward, Thomas E. Lane and Michael P. Cancro
    J Immunol June 1, 2012, 188 (11) 5257-5266; DOI: https://doi.org/10.4049/jimmunol.1101934
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    PTPN22 Alters the Development of Regulatory T Cells in the Thymus
    Christian J. Maine, Emma E. Hamilton-Williams, Jocelyn Cheung, Stephanie M. Stanford, Nunzio Bottini, Linda S. Wicker and Linda A. Sherman
    J Immunol June 1, 2012, 188 (11) 5267-5275; DOI: https://doi.org/10.4049/jimmunol.1200150
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    1,25-Dihyroxyvitamin D3 Promotes FOXP3 Expression via Binding to Vitamin D Response Elements in Its Conserved Noncoding Sequence Region
    Seong Wook Kang, Sang Hyun Kim, Naeun Lee, Won-Woo Lee, Kyung-A Hwang, Min Sun Shin, Seung-Hyun Lee, Wan-Uk Kim and Insoo Kang
    J Immunol June 1, 2012, 188 (11) 5276-5282; DOI: https://doi.org/10.4049/jimmunol.1101211
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    Two Preferentially Expressed Proteins Protect Vascular Endothelial Cells from an Attack by Peptide-Specific CTL
    Daniela S. Thommen, Heiko Schuster, Mario Keller, Sarika Kapoor, Andreas O. Weinzierl, Cuddapah S. Chennakesava, Xueya Wang, Lucia Rohrer, Arnold von Eckardstein, Stefan Stevanovic and Barbara C. Biedermann
    J Immunol June 1, 2012, 188 (11) 5283-5292; DOI: https://doi.org/10.4049/jimmunol.1101506
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    Integrin CD11b Negatively Regulates TLR9-Triggered Dendritic Cell Cross-Priming by Upregulating microRNA-146a
    Yi Bai, Cheng Qian, Li Qian, Feng Ma, Jin Hou, Yongjian Chen, Qingqing Wang and Xuetao Cao
    J Immunol June 1, 2012, 188 (11) 5293-5302; DOI: https://doi.org/10.4049/jimmunol.1102371
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    Prostaglandin E2 Affects T Cell Responses through Modulation of CD46 Expression
    Karoline Kickler, Kathryn Maltby, Siobhán Ni Choileain, Jillian Stephen, Sheila Wright, David A. Hafler, Henry N. Jabbour and Anne L. Astier
    J Immunol June 1, 2012, 188 (11) 5303-5310; DOI: https://doi.org/10.4049/jimmunol.1103090
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    Tripartite Motif-Containing Protein 38 Negatively Regulates TLR3/4- and RIG-I–Mediated IFN-β Production and Antiviral Response by Targeting NAP1
    Wei Zhao, Lijuan Wang, Meng Zhang, Peng Wang, Chao Yuan, Jianni Qi, Hong Meng and Chengjiang Gao
    J Immunol June 1, 2012, 188 (11) 5311-5318; DOI: https://doi.org/10.4049/jimmunol.1103506
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    Dendritic Cells Activated by IFN-γ/STAT1 Express IL-31 Receptor and Release Proinflammatory Mediators upon IL-31 Treatment
    Jutta Horejs-Hoeck, Harald Schwarz, Sebastian Lamprecht, Elisabeth Maier, Stefan Hainzl, Maria Schmittner, Gernot Posselt, Angelika Stoecklinger, Thomas Hawranek and Albert Duschl
    J Immunol June 1, 2012, 188 (11) 5319-5326; DOI: https://doi.org/10.4049/jimmunol.1101044
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    ATP Binding Cassette Transporter G1 Deletion Induces IL-17–Dependent Dysregulation of Pulmonary Adaptive Immunity
    David W. Draper, Kymberly M. Gowdy, Jennifer H. Madenspacher, Rhonda H. Wilson, Gregory S. Whitehead, Hideki Nakano, Arun R. Pandiri, Julie F. Foley, Alan T. Remaley, Donald N. Cook and Michael B. Fessler
    J Immunol June 1, 2012, 188 (11) 5327-5336; DOI: https://doi.org/10.4049/jimmunol.1101605
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    Protein Kinase C-θ Inhibits Inducible Regulatory T Cell Differentiation via an AKT-Foxo1/3a–Dependent Pathway
    Jian Ma, Yan Ding, Xianfeng Fang, Ruiqing Wang and Zuoming Sun
    J Immunol June 1, 2012, 188 (11) 5337-5347; DOI: https://doi.org/10.4049/jimmunol.1102979
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    IRF5 Risk Polymorphisms Contribute to Interindividual Variance in Pattern Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells
    Matija Hedl and Clara Abraham
    J Immunol June 1, 2012, 188 (11) 5348-5356; DOI: https://doi.org/10.4049/jimmunol.1103319
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    Polyinosinic-Polycytidylic Acid Limits Tumor Outgrowth in a Mouse Model of Metastatic Lung Cancer
    Giovanni Forte, Alessia Rega, Silvana Morello, Antonio Luciano, Claudio Arra, Aldo Pinto and Rosalinda Sorrentino
    J Immunol June 1, 2012, 188 (11) 5357-5364; DOI: https://doi.org/10.4049/jimmunol.1103811
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    Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release
    Padmini Jayaraman, Falguni Parikh, Esther Lopez-Rivera, Yared Hailemichael, Amelia Clark, Ge Ma, David Cannan, Marcel Ramacher, Masashi Kato, Willem W. Overwijk, Shu-Hsia Chen, Viktor Y. Umansky and Andrew G. Sikora
    J Immunol June 1, 2012, 188 (11) 5365-5376; DOI: https://doi.org/10.4049/jimmunol.1103553
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    Alternative Splicing Controlled by Heterogeneous Nuclear Ribonucleoprotein L Regulates Development, Proliferation, and Migration of Thymic Pre-T Cells
    Marie-Claude Gaudreau, Florian Heyd, Rachel Bastien, Brian Wilhelm and Tarik Möröy
    J Immunol June 1, 2012, 188 (11) 5377-5388; DOI: https://doi.org/10.4049/jimmunol.1103142
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    Long-Lived Bone Marrow Plasma Cells Are Induced Early in Response to T Cell-Independent or T Cell-Dependent Antigens
    Alexandra Bortnick, Irene Chernova, William J. Quinn III, Monica Mugnier, Michael P. Cancro and David Allman
    J Immunol June 1, 2012, 188 (11) 5389-5396; DOI: https://doi.org/10.4049/jimmunol.1102808
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    Dendritic Cell-Specific Ablation of the Protein Tyrosine Phosphatase Shp1 Promotes Th1 Cell Differentiation and Induces Autoimmunity
    Tetsuya Kaneko, Yasuyuki Saito, Takenori Kotani, Hideki Okazawa, Hiroko Iwamura, Miho Sato-Hashimoto, Yoshitake Kanazawa, Satoshi Takahashi, Keiju Hiromura, Shinya Kusakari, Yoriaki Kaneko, Yoji Murata, Hiroshi Ohnishi, Yoshihisa Nojima, Kenji Takagishi and Takashi Matozaki
    J Immunol June 1, 2012, 188 (11) 5397-5407; DOI: https://doi.org/10.4049/jimmunol.1103210
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    Runx1 Deficiency in CD4+ T Cells Causes Fatal Autoimmune Inflammatory Lung Disease Due to Spontaneous Hyperactivation of Cells
    Won Fen Wong, Kazuyoshi Kohu, Akira Nakamura, Masahito Ebina, Toshiaki Kikuchi, Ryushi Tazawa, Keisuke Tanaka, Shunsuke Kon, Tomo Funaki, Akiko Sugahara-Tobinai, Chung Yeng Looi, Shota Endo, Ryo Funayama, Mineo Kurokawa, Sonoko Habu, Naoto Ishii, Manabu Fukumoto, Koh Nakata, Toshiyuki Takai and Masanobu Satake
    J Immunol June 1, 2012, 188 (11) 5408-5420; DOI: https://doi.org/10.4049/jimmunol.1102991
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    Stathmin Regulates Microtubule Dynamics and Microtubule Organizing Center Polarization in Activated T Cells
    Erin L. Filbert, Marie Le Borgne, Joseph Lin, John E. Heuser and Andrey S. Shaw
    J Immunol June 1, 2012, 188 (11) 5421-5427; DOI: https://doi.org/10.4049/jimmunol.1200242
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    Stem Cell Factor Programs the Mast Cell Activation Phenotype
    Tomonobu Ito, Daniel Smrž, Mi-Yeon Jung, Geethani Bandara, Avanti Desai, Šárka Smržová, Hye Sun Kuehn, Michael A. Beaven, Dean D. Metcalfe and Alasdair M. Gilfillan
    J Immunol June 1, 2012, 188 (11) 5428-5437; DOI: https://doi.org/10.4049/jimmunol.1103366
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    Human Th17 Cells Express High Levels of Enzymatically Active Dipeptidylpeptidase IV (CD26)
    Bertram Bengsch, Bianca Seigel, Tobias Flecken, Julia Wolanski, Hubert E. Blum and Robert Thimme
    J Immunol June 1, 2012, 188 (11) 5438-5447; DOI: https://doi.org/10.4049/jimmunol.1103801
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    Wnt5a Induces a Tolerogenic Phenotype of Macrophages in Sepsis and Breast Cancer Patients
    Caroline Bergenfelz, Catharina Medrek, Elin Ekström, Karin Jirström, Helena Janols, Marlene Wullt, Anders Bredberg and Karin Leandersson
    J Immunol June 1, 2012, 188 (11) 5448-5458; DOI: https://doi.org/10.4049/jimmunol.1103378
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    Kinetics and Activation Requirements of Contact-Dependent Immune Suppression by Human Regulatory T Cells
    Morten Hagness, Karen Henjum, Johannes Landskron, Kristoffer Watten Brudvik, Bjørn Atle Bjørnbeth, Aksel Foss, Kjetil Taskén and Einar Martin Aandahl
    J Immunol June 1, 2012, 188 (11) 5459-5466; DOI: https://doi.org/10.4049/jimmunol.1101367
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    Strong Impact of CD4+Foxp3+ Regulatory T Cells and Limited Effect of T Cell-Derived IL-10 on Pathogen Clearance during Plasmodium yoelii Infection
    Simone Abel, Nadja Lückheide, Astrid M. Westendorf, Robert Geffers, Axel Roers, Werner Müller, Tim Sparwasser, Kai Matuschewski, Jan Buer and Wiebke Hansen
    J Immunol June 1, 2012, 188 (11) 5467-5477; DOI: https://doi.org/10.4049/jimmunol.1102223
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    IL-10+CTLA-4+ Th2 Inhibitory Cells Form in a Foxp3-Independent, IL-2–Dependent Manner from Th2 Effectors during Chronic Inflammation
    John A. Altin, Chris C. Goodnow and Matthew C. Cook
    J Immunol June 1, 2012, 188 (11) 5478-5488; DOI: https://doi.org/10.4049/jimmunol.1102994
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    CD13 Regulates Dendritic Cell Cross-Presentation and T Cell Responses by Inhibiting Receptor-Mediated Antigen Uptake
    Mallika Ghosh, Beata McAuliffe, Jaganathan Subramani, Sreyashi Basu and Linda H. Shapiro
    J Immunol June 1, 2012, 188 (11) 5489-5499; DOI: https://doi.org/10.4049/jimmunol.1103490
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    MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN
    Yang Liu, Lihua Lai, Qingyun Chen, Yinjing Song, Sheng Xu, Feng Ma, Xiaojian Wang, Jianli Wang, Hai Yu, Xuetao Cao and Qingqing Wang
    J Immunol June 1, 2012, 188 (11) 5500-5510; DOI: https://doi.org/10.4049/jimmunol.1103505

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Crystal Structure of Cell Adhesion Molecule Nectin-2/CD112 and Its Binding to Immune Receptor DNAM-1/CD226
    Jun Liu, Xiaomin Qian, Zhujun Chen, Xiang Xu, Feng Gao, Shuijun Zhang, Rongguang Zhang, Jianxun Qi, George F. Gao and Jinghua Yan
    J Immunol June 1, 2012, 188 (11) 5511-5520; DOI: https://doi.org/10.4049/jimmunol.1200324
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    CD40 Stimulates a “Feed-Forward” NF-κB–Driven Molecular Pathway That Regulates IFN-β Expression in Carcinoma Cells
    Aristides Moschonas, Marina Ioannou and Aristides G. Eliopoulos
    J Immunol June 1, 2012, 188 (11) 5521-5527; DOI: https://doi.org/10.4049/jimmunol.1200133
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    Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase ζ Activity
    Janssen Daly, Katarzyna Bebenek, Danielle L. Watt, Kathleen Richter, Chuancang Jiang, Ming-Lang Zhao, Madhumita Ray, W. Glenn McGregor, Thomas A. Kunkel and Marilyn Diaz
    J Immunol June 1, 2012, 188 (11) 5528-5537; DOI: https://doi.org/10.4049/jimmunol.1102629
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    Incorporation of Transmembrane Hydrophobic Mutations in the TCR Enhance Its Surface Expression and T Cell Functional Avidity
    Astar Haga-Friedman, Miryam Horovitz-Fried and Cyrille J. Cohen
    J Immunol June 1, 2012, 188 (11) 5538-5546; DOI: https://doi.org/10.4049/jimmunol.1103020
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    E2A and CBP/p300 Act in Synergy To Promote Chromatin Accessibility of the Immunoglobulin κ Locus
    Shuji Sakamoto, Kousho Wakae, Yuki Anzai, Kiyohito Murai, Nobuyuki Tamaki, Masaki Miyazaki, Kazuko Miyazaki, William J. Romanow, Tomokatsu Ikawa, Daisuke Kitamura, Itaru Yanagihara, Nagahiro Minato, Cornelis Murre and Yasutoshi Agata
    J Immunol June 1, 2012, 188 (11) 5547-5560; DOI: https://doi.org/10.4049/jimmunol.1002346

IMMUNOGENETICS

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    The Size of the Plasmacytoid Dendritic Cell Compartment Is a Multigenic Trait Dominated by a Locus on Mouse Chromosome 7
    Adam-Nicolas Pelletier, Fanny Guimont-Desrochers, Michelle P. Ashton, Thomas C. Brodnicki and Sylvie Lesage
    J Immunol June 1, 2012, 188 (11) 5561-5570; DOI: https://doi.org/10.4049/jimmunol.1102136
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    Essential Role of IL-4 and IL-4Rα Interaction in Adaptive Immunity of Zebrafish: Insight into the Origin of Th2-like Regulatory Mechanism in Ancient Vertebrates
    Lv-yun Zhu, Ping-ping Pan, Wei Fang, Jian-zhong Shao and Li-xin Xiang
    J Immunol June 1, 2012, 188 (11) 5571-5584; DOI: https://doi.org/10.4049/jimmunol.1102259

HOST DEFENSE

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    Soluble Trem-like Transcript-1 Regulates Leukocyte Activation and Controls Microbial Sepsis
    Marc Derive, Youcef Bouazza, Nacira Sennoun, Sandra Marchionni, Laura Quigley, Valance Washington, Frédéric Massin, Jean-Pierre Max, Jill Ford, Corentine Alauzet, Bruno Levy, Daniel W. McVicar and Sébastien Gibot
    J Immunol June 1, 2012, 188 (11) 5585-5592; DOI: https://doi.org/10.4049/jimmunol.1102674
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    Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPARγ and TR4 for Survival
    Sahil Mahajan, H. Kitdorlang Dkhar, Vemika Chandra, Sandeep Dave, Ravikanth Nanduri, Ashok Kumar Janmeja, Javed N. Agrewala and Pawan Gupta
    J Immunol June 1, 2012, 188 (11) 5593-5603; DOI: https://doi.org/10.4049/jimmunol.1103038
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    Mast Cell TLR2 Signaling Is Crucial for Effective Killing of Francisella tularensis
    Annette R. Rodriguez, Jieh-Juen Yu, M. Neal Guentzel, Christopher S. Navara, Karl E. Klose, Thomas G. Forsthuber, James P. Chambers, Michael T. Berton and Bernard P. Arulanandam
    J Immunol June 1, 2012, 188 (11) 5604-5611; DOI: https://doi.org/10.4049/jimmunol.1200039
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    Delays and Diversions Mark the Development of B Cell Responses to Borrelia burgdorferi Infection
    Christine J. Hastey, Rebecca A. Elsner, Stephen W. Barthold and Nicole Baumgarth
    J Immunol June 1, 2012, 188 (11) 5612-5622; DOI: https://doi.org/10.4049/jimmunol.1103735
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    NLRC4 Inflammasome-Mediated Production of IL-1β Modulates Mucosal Immunity in the Lung against Gram-Negative Bacterial Infection
    Shanshan Cai, Sanjay Batra, Nobuko Wakamatsu, Pal Pacher and Samithamby Jeyaseelan
    J Immunol June 1, 2012, 188 (11) 5623-5635; DOI: https://doi.org/10.4049/jimmunol.1200195
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    A Novel Th Cell Epitope of Candida albicans Mediates Protection from Fungal Infection
    Eva Bär, André Gladiator, Sonia Bastidas, Bernd Roschitzki, Hans Acha-Orbea, Annette Oxenius and Salomé LeibundGut-Landmann
    J Immunol June 1, 2012, 188 (11) 5636-5643; DOI: https://doi.org/10.4049/jimmunol.1200594
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    Dectin-1 Stimulation Induces Suppressor of Cytokine Signaling 1, Thereby Modulating TLR Signaling and T Cell Responses
    Mariel E. Eberle and Alexander H. Dalpke
    J Immunol June 1, 2012, 188 (11) 5644-5654; DOI: https://doi.org/10.4049/jimmunol.1103068
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    CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis
    Makoto Ishii, Koichiro Asano, Ho Namkoong, Sadatomo Tasaka, Kosuke Mizoguchi, Takahiro Asami, Hirofumi Kamata, Yoshifumi Kimizuka, Hiroshi Fujiwara, Yohei Funatsu, Shizuko Kagawa, Jun Miyata, Ken Ishii, Masataka Nakamura, Hiroyuki Hirai, Kinya Nagata, Steven L. Kunkel, Naoki Hasegawa and Tomoko Betsuyaku
    J Immunol June 1, 2012, 188 (11) 5655-5664; DOI: https://doi.org/10.4049/jimmunol.1102330

INFLAMMATION

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    Regulation of Cytosolic Phospholipase A2 Phosphorylation by Proteolytic Cleavage of Annexin A1 in Activated Mast Cells
    Joon Hyun Kwon, Jea Hwang Lee, Ki Soon Kim, Youn Wook Chung and Ick Young Kim
    J Immunol June 1, 2012, 188 (11) 5665-5673; DOI: https://doi.org/10.4049/jimmunol.1102306
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    Severe Impairment of Leukocyte Recruitment in ppGalNAcT-1–Deficient Mice
    Helena Block, Klaus Ley and Alexander Zarbock
    J Immunol June 1, 2012, 188 (11) 5674-5681; DOI: https://doi.org/10.4049/jimmunol.1200392
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    Complement Protein C1q Directs Macrophage Polarization and Limits Inflammasome Activity during the Uptake of Apoptotic Cells
    Marie E. Benoit, Elizabeth V. Clarke, Pedro Morgado, Deborah A. Fraser and Andrea J. Tenner
    J Immunol June 1, 2012, 188 (11) 5682-5693; DOI: https://doi.org/10.4049/jimmunol.1103760
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    Complement C3a-Induced IL-17 Plays a Critical Role in an IgE-Mediated Late-Phase Asthmatic Response and Airway Hyperresponsiveness via Neutrophilic Inflammation in Mice
    Nobuaki Mizutani, Hirofumi Goshima, Takeshi Nabe and Shin Yoshino
    J Immunol June 1, 2012, 188 (11) 5694-5705; DOI: https://doi.org/10.4049/jimmunol.1103176
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    TLR9 Provokes Inflammation in Response to Fetal DNA: Mechanism for Fetal Loss in Preterm Birth and Preeclampsia
    Andrea Scharfe-Nugent, Sinéad C. Corr, Susan B. Carpenter, Louise Keogh, Brendan Doyle, Cara Martin, Katherine A. Fitzgerald, Sean Daly, John J. O’Leary and Luke A. J. O’Neill
    J Immunol June 1, 2012, 188 (11) 5706-5712; DOI: https://doi.org/10.4049/jimmunol.1103454
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    A2A Adenosine Receptor Signaling in Lymphocytes and the Central Nervous System Regulates Inflammation during Experimental Autoimmune Encephalomyelitis
    Jeffrey H. Mills, Do-Geun Kim, Antje Krenz, Jiang-Fan Chen and Margaret S. Bynoe
    J Immunol June 1, 2012, 188 (11) 5713-5722; DOI: https://doi.org/10.4049/jimmunol.1200545
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    Ceramide Synthase 6 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis
    Susanne Schiffmann, Nerea Ferreiros, Kerstin Birod, Max Eberle, Yannick Schreiber, Waltraud Pfeilschifter, Ulf Ziemann, Sandra Pierre, Klaus Scholich, Sabine Grösch and Gerd Geisslinger
    J Immunol June 1, 2012, 188 (11) 5723-5733; DOI: https://doi.org/10.4049/jimmunol.1103109
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    Protective Role of Reactive Oxygen Species in Endotoxin-Induced Lung Inflammation through Modulation of IL-10 Expression
    Jing Deng, Xuerong Wang, Feng Qian, Stephen Vogel, Lei Xiao, Ravi Ranjan, Hyesuk Park, Manjula Karpurapu, Richard D. Ye, Gye Young Park and John W. Christman
    J Immunol June 1, 2012, 188 (11) 5734-5740; DOI: https://doi.org/10.4049/jimmunol.1101323
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    TRPV1 Deletion Enhances Local Inflammation and Accelerates the Onset of Systemic Inflammatory Response Syndrome
    Elizabeth S. Fernandes, Lihuan Liang, Sarah-Jane Smillie, Frank Kaiser, Robert Purcell, Damian W. Rivett, Saydul Alam, Sarah Howat, Helen Collins, Stephen J. Thompson, Julie E. Keeble, Yanira Riffo-Vasquez, Kenneth D. Bruce and Susan D. Brain
    J Immunol June 1, 2012, 188 (11) 5741-5751; DOI: https://doi.org/10.4049/jimmunol.1102147
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    Defining GM-CSF– and Macrophage-CSF–Dependent Macrophage Responses by In Vitro Models
    Derek C. Lacey, Adrian Achuthan, Andrew J. Fleetwood, Hang Dinh, John Roiniotis, Glen M. Scholz, Melody W. Chang, Sandra K. Beckman, Andrew D. Cook and John A. Hamilton
    J Immunol June 1, 2012, 188 (11) 5752-5765; DOI: https://doi.org/10.4049/jimmunol.1103426

CLINICAL IMMUNOLOGY

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    Beyond HLA-A*0201: New HLA-Transgenic Nonobese Diabetic Mouse Models of Type 1 Diabetes Identify the Insulin C-Peptide as a Rich Source of CD8+ T Cell Epitopes
    Zoltan Antal, Jason C. Baker, Carla Smith, Irene Jarchum, Jeffrey Babad, Gayatri Mukherjee, Yang Yang, John Sidney, Alessandro Sette, Pere Santamaria and Teresa P. DiLorenzo
    J Immunol June 1, 2012, 188 (11) 5766-5775; DOI: https://doi.org/10.4049/jimmunol.1102930
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    Cyr61 Induces IL-6 Production by Fibroblast-like Synoviocytes Promoting Th17 Differentiation in Rheumatoid Arthritis
    Jinpiao Lin, Zhou Zhou, Rongfen Huo, Lianbo Xiao, Guilin Ouyang, Li Wang, Yue Sun, Baihua Shen, Dangsheng Li and Ningli Li
    J Immunol June 1, 2012, 188 (11) 5776-5784; DOI: https://doi.org/10.4049/jimmunol.1103201
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    Role of CD25+ Dendritic Cells in the Generation of Th17 Autoreactive T Cells in Autoimmune Experimental Uveitis
    Dongchun Liang, Aijun Zuo, Hui Shao, Willi K. Born, Rebecca L. O’Brien, Henry J. Kaplan and Deming Sun
    J Immunol June 1, 2012, 188 (11) 5785-5791; DOI: https://doi.org/10.4049/jimmunol.1200109
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    Antibodies to Pathogenic Epitopes on Type XVII Collagen Cause Skin Fragility in a Complement-Dependent and -Independent Manner
    Ken Natsuga, Wataru Nishie, Satoru Shinkuma, Hideyuki Ujiie, Machiko Nishimura, Daisuke Sawamura and Hiroshi Shimizu
    J Immunol June 1, 2012, 188 (11) 5792-5799; DOI: https://doi.org/10.4049/jimmunol.1003402

LETTERS OF RETRACTION

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    Retraction: CD226 Expression Deficiency Causes High Sensitivity to Apoptosis in NK T Cells from Patients with Systemic Lupus Erythematosus
    Deng Tao, Liu Shangwu, Liu Yan, Liu Junyan, Gong Feili, Jin Boquan and Tan Jinquan
    J Immunol June 1, 2012, 188 (11) 5800; DOI: https://doi.org/10.4049/jimmunol.1290020
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    Retraction: Vα24-Invariant NKT Cells from Patients with Allergic Asthma Express CCR9 at High Frequency and Induce Th2 Bias of CD3+ T Cells upon CD226 Engagement
    Yang Sen, Bi Yongyi, He Yuling, Xie Luokun, He Li, Xiong Jie, Deng Tao, Zhou Gang, Liu Junyan, Hu Chunsong, Zhang Xuejun, Jin Youxin, Gong Feili, Jin Boquan and Tan Jinquan
    J Immunol June 1, 2012, 188 (11) 5801; DOI: https://doi.org/10.4049/jimmunol.1290021

CORRECTIONS

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    Correction: TREM2 and β-catenin regulate bone homeostasis by controlling the rate of osteoclastogenesis
    Karel Otero, Masahiro Shinohara, Haibo Zhao, Marina Cella, Susan Gilfillan, Angela Colucci, Roberta Faccio, F. Patrick Ross, Steve L. Teitelbaum, Hiroshi Takayanagi and Marco Colonna
    J Immunol June 1, 2012, 188 (11) 5802; DOI: https://doi.org/10.4049/jimmunol.1290014
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The Journal of Immunology: 188 (11)
The Journal of Immunology
Vol. 188, Issue 11
1 Jun 2012
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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