The Journal of Immunology: 187 (6)

September 15, 2011; Volume 187,Issue 6

IN THIS ISSUE

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In This Issue
J Immunol September 15, 2011, 187 (6) 2839-2840; DOI: https://doi.org/10.4049/jimmunol.1190049

BRIEF REVIEWS

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The BTB-ZF Family of Transcription Factors: Key Regulators of Lineage Commitment and Effector Function Development in the Immune System
Aimee M. Beaulieu and Derek B. Sant'Angelo

J Immunol September 15, 2011, 187 (6) 2841-2847; DOI: https://doi.org/10.4049/jimmunol.1004006

CUTTING EDGE

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Cutting Edge: Crohn’s Disease-Associated Nod2 Mutation Limits Production of Proinflammatory Cytokines To Protect the Host from Enterococcus faecalis-Induced Lethality
Yun-Gi Kim, Michael H. Shaw, Neil Warner, Jong-Hwan Park, Felicia Chen, Yasunori Ogura and Gabriel Núñez

J Immunol September 15, 2011, 187 (6) 2849-2852; DOI: https://doi.org/10.4049/jimmunol.1001854

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Cytoplasmic Igα Serine/Threonines Fine-Tune Igα Tyrosine Phosphorylation and Limit Bone Marrow Plasma Cell Formation
Heide Christine Patterson, Manfred Kraus, Donghai Wang, Aliakbar Shahsafaei, Joel M. Henderson, Jane Seagal, Kevin L. Otipoby, To-Ha Thai and Klaus Rajewsky

J Immunol September 15, 2011, 187 (6) 2853-2858; DOI: https://doi.org/10.4049/jimmunol.1101143
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Development of Memory-Like Autoregulatory CD8⁺ T Cells Is CD4⁺ T Cell Dependent
Afshin Shameli, Xavier Clemente-Casares, Jinguo Wang and Pere Santamaria

J Immunol September 15, 2011, 187 (6) 2859-2866; DOI: https://doi.org/10.4049/jimmunol.1101117
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Long-Lived Plasma Cells from Human Small Intestine Biopsies Secrete Immunoglobulins for Many Weeks In Vitro
Luka Mesin, Roberto Di Niro, Keith M. Thompson, Knut E. A. Lundin and Ludvig M. Sollid

J Immunol September 15, 2011, 187 (6) 2867-2874; DOI: https://doi.org/10.4049/jimmunol.1003181
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Suppressor of Cytokine Signaling 2 Is a Feedback Inhibitor of TLR-Induced Activation in Human Monocyte-Derived Dendritic Cells
Gernot Posselt, Harald Schwarz, Albert Duschl and Jutta Horejs-Hoeck

J Immunol September 15, 2011, 187 (6) 2875-2884; DOI: https://doi.org/10.4049/jimmunol.1003348
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Heterogeneous and Tissue-Specific Regulation of Effector T Cell Responses by IFN-γ during Plasmodium berghei ANKA Infection
Ana Villegas-Mendez, J. Brian de Souza, Linda Murungi, Julius C. R. Hafalla, Tovah N. Shaw, Rachel Greig, Eleanor M. Riley and Kevin N. Couper

J Immunol September 15, 2011, 187 (6) 2885-2897; DOI: https://doi.org/10.4049/jimmunol.1100241
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NKT Cells Are Required for Complete Freund’s Adjuvant-Mediated Protection from Autoimmune Diabetes
I-Fang Lee, Peter van den Elzen, Rusung Tan and John J. Priatel

J Immunol September 15, 2011, 187 (6) 2898-2904; DOI: https://doi.org/10.4049/jimmunol.1002551
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CD204 Suppresses Large Heat Shock Protein-Facilitated Priming of Tumor Antigen gp100-Specific T Cells and Chaperone Vaccine Activity against Mouse Melanoma
Jie Qian, Huanfa Yi, Chunqing Guo, Xiaofei Yu, Daming Zuo, Xing Chen, John M. Kane III, Elizabeth A. Repasky, John R. Subjeck and Xiang-Yang Wang

J Immunol September 15, 2011, 187 (6) 2905-2914; DOI: https://doi.org/10.4049/jimmunol.1100703
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Development of Autoimmune Diabetes in the Absence of Detectable IL-17A in a CD8-Driven Virally Induced Model
Tom L. Van Belle, Enric Esplugues, Jeanette Liao, Therese Juntti, Richard A. Flavell and Matthias G. von Herrath

J Immunol September 15, 2011, 187 (6) 2915-2922; DOI: https://doi.org/10.4049/jimmunol.1000180
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The Impact of Pre-Existing Memory on Differentiation of Newly Recruited Naive CD8 T Cells
Matthew D. Martin, Thomas C. Wirth, Peter Lauer, John T. Harty and Vladimir P. Badovinac

J Immunol September 15, 2011, 187 (6) 2923-2931; DOI: https://doi.org/10.4049/jimmunol.1100698
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HIV-Mediated Phosphatidylinositol 3-Kinase/Serine–Threonine Kinase Activation in APCs Leads to Programmed Death-1 Ligand Upregulation and Suppression of HIV-Specific CD8 T Cells
Karuppiah Muthumani, Devon J. Shedlock, Daniel K. Choo, Paolo Fagone, Omkar U. Kawalekar, Jonathan Goodman, Chaoran B. Bian, Aarti A. Ramanathan, Parikh Atman, Pablo Tebas, Michael A. Chattergoon, Andrew Y. Choo and David B. Weiner

J Immunol September 15, 2011, 187 (6) 2932-2943; DOI: https://doi.org/10.4049/jimmunol.1100594
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IL-10 Restricts Activation-Induced Death of NK Cells during Acute Murine Cytomegalovirus Infection
Maria A. Stacey, Morgan Marsden, Eddie C. Y. Wang, Gavin W. G. Wilkinson and Ian R. Humphreys

J Immunol September 15, 2011, 187 (6) 2944-2952; DOI: https://doi.org/10.4049/jimmunol.1101021
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TLR9 in Peritoneal B-1b Cells Is Essential for Production of Protective Self-Reactive IgM To Control Th17 Cells and Severe Autoimmunity
Alexander D. Stoehr, Carolin T. Schoen, Maria M. M. Mertes, Susanne Eiglmeier, Vivien Holecska, Alexandra K. Lorenz, Tim Schommartz, Anna-Lena Schoen, Constanze Hess, André Winkler, Hedda Wardemann and Marc Ehlers

J Immunol September 15, 2011, 187 (6) 2953-2965; DOI: https://doi.org/10.4049/jimmunol.1003340
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Ubiquitination of CD86 Is a Key Mechanism in Regulating Antigen Presentation by Dendritic Cells
Günther Baravalle, Hyesuk Park, Megan McSweeney, Mari Ohmura-Hoshino, Yohei Matsuki, Satoshi Ishido and Jeoung-Sook Shin

J Immunol September 15, 2011, 187 (6) 2966-2973; DOI: https://doi.org/10.4049/jimmunol.1101643
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Stem Cell Factor Consistently Improves Thymopoiesis after Experimental Transplantation of Murine or Human Hematopoietic Stem Cells in Immunodeficient Mice
Evert-Jan Wils, Elwin J. C. Rombouts, Irene van Mourik, Hergen Spits, Nicolas Legrand, Eric Braakman and Jan J. Cornelissen

J Immunol September 15, 2011, 187 (6) 2974-2981; DOI: https://doi.org/10.4049/jimmunol.1004209
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Miz-1 Is Required To Coordinate the Expression of TCRβ and p53 Effector Genes at the Pre-TCR “β-Selection” Checkpoint
Ingrid Saba, Christian Kosan, Lothar Vassen, Ludger Klein-Hitpass and Tarik Möröy

J Immunol September 15, 2011, 187 (6) 2982-2992; DOI: https://doi.org/10.4049/jimmunol.1101451
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Caveolin-1 Orchestrates TCR Synaptic Polarity, Signal Specificity, and Function in CD8 T Cells
Tamar Tomassian, Lisa A. Humphries, Scot D. Liu, Oscar Silva, David G. Brooks and M. Carrie Miceli

J Immunol September 15, 2011, 187 (6) 2993-3002; DOI: https://doi.org/10.4049/jimmunol.1101447
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Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF-β1–Dependent and –Independent Mechanisms
Su Mi, Zhe Li, Hong-Zhen Yang, Hong Liu, Jia-Ping Wang, Yong-Gang Ma, Xiao-Xing Wang, Han-Zhi Liu, Wei Sun and Zhuo-Wei Hu

J Immunol September 15, 2011, 187 (6) 3003-3014; DOI: https://doi.org/10.4049/jimmunol.1004081
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The Actin-Bundling Protein L-Plastin Is Essential for Marginal Zone B Cell Development
Elizabeth M. Todd, Lauren E. Deady and Sharon Celeste Morley

J Immunol September 15, 2011, 187 (6) 3015-3025; DOI: https://doi.org/10.4049/jimmunol.1101033
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EBI2 Guides Serial Movements of Activated B Cells and Ligand Activity Is Detectable in Lymphoid and Nonlymphoid Tissues
Lisa M. Kelly, João P. Pereira, Tangsheng Yi, Ying Xu and Jason G. Cyster

J Immunol September 15, 2011, 187 (6) 3026-3032; DOI: https://doi.org/10.4049/jimmunol.1101262
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CpG and Non-CpG Oligodeoxynucleotides Directly Costimulate Mouse and Human CD4⁺ T Cells through a TLR9- and MyD88-Independent Mechanism
Angela Landrigan, Michael T. Wong and Paul J. Utz

J Immunol September 15, 2011, 187 (6) 3033-3043; DOI: https://doi.org/10.4049/jimmunol.1003414
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Mucosa-Associated Epithelial Chemokine/CCL28 Expression in the Uterus Attracts CCR10⁺ IgA Plasma Cells following Mucosal Vaccination via Estrogen Control
Hye-Ran Cha, Hyun-Jeong Ko, Eun-Do Kim, Sun-Young Chang, Sang-Uk Seo, Nicolas Cuburu, Sangryeol Ryu, Sunghoon Kim and Mi-Na Kweon

J Immunol September 15, 2011, 187 (6) 3044-3052; DOI: https://doi.org/10.4049/jimmunol.1100402
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Myosin 1c Participates in B Cell Cytoskeleton Rearrangements, Is Recruited to the Immunologic Synapse, and Contributes to Antigen Presentation
José L. Maravillas-Montero, Peter G. Gillespie, Genaro Patiño-López, Stephen Shaw and Leopoldo Santos-Argumedo

J Immunol September 15, 2011, 187 (6) 3053-3063; DOI: https://doi.org/10.4049/jimmunol.1004018
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Posttranslational Modification of Gluten Shapes TCR Usage in Celiac Disease
Shuo-Wang Qiao, Melinda Ráki, Kristin S. Gunnarsen, Geir-Åge Løset, Knut E. A. Lundin, Inger Sandlie and Ludvig M. Sollid

J Immunol September 15, 2011, 187 (6) 3064-3071; DOI: https://doi.org/10.4049/jimmunol.1101526
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The Facultative Intracellular Pathogen Candida glabrata Subverts Macrophage Cytokine Production and Phagolysosome Maturation
Katja Seider, Sascha Brunke, Lydia Schild, Nadja Jablonowski, Duncan Wilson, Olivia Majer, Dagmar Barz, Albert Haas, Karl Kuchler, Martin Schaller and Bernhard Hube

J Immunol September 15, 2011, 187 (6) 3072-3086; DOI: https://doi.org/10.4049/jimmunol.1003730
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TRAIL/DR5 Plays a Critical Role in NK Cell-Mediated Negative Regulation of Dendritic Cell Cross-Priming of T Cells
Mitsuhiro Iyori, Tong Zhang, Haddon Pantel, Bethany A. Gagne and Charles L. Sentman

J Immunol September 15, 2011, 187 (6) 3087-3095; DOI: https://doi.org/10.4049/jimmunol.1003879
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Recognition and Killing of Human and Murine Pancreatic β Cells by the NK Receptor NKp46
Chamutal Gur, Jonatan Enk, Sameer A. Kassem, Yaron Suissa, Judith Magenheim, Miri Stolovich-Rain, Tomer Nir, Hagit Achdout, Benjamin Glaser, James Shapiro, Yaakov Naparstek, Angel Porgador, Yuval Dor and Ofer Mandelboim

J Immunol September 15, 2011, 187 (6) 3096-3103; DOI: https://doi.org/10.4049/jimmunol.1101269
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Aryl Hydrocarbon Receptor Is Critical for Homeostasis of Invariant γδ T Cells in the Murine Epidermis
Stephanie Kadow, Bettina Jux, Sonja P. Zahner, Britta Wingerath, Stefanie Chmill, Björn E. Clausen, Jan Hengstler and Charlotte Esser

J Immunol September 15, 2011, 187 (6) 3104-3110; DOI: https://doi.org/10.4049/jimmunol.1100912
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Hierarchical IL-5 Expression Defines a Subpopulation of Highly Differentiated Human Th2 Cells
Bhaskar Upadhyaya, Yuzhi Yin, Brenna J. Hill, Daniel C. Douek and Calman Prussin

J Immunol September 15, 2011, 187 (6) 3111-3120; DOI: https://doi.org/10.4049/jimmunol.1101283
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Functional Gap Junctions Accumulate at the Immunological Synapse and Contribute to T Cell Activation
Ariadna Mendoza-Naranjo, Gerben Bouma, Cristián Pereda, Marcos Ramírez, Kevin F. Webb, Andrés Tittarelli, Mercedes N. López, Alexis M. Kalergis, Adrian J. Thrasher, David L. Becker and Flavio Salazar-Onfray

J Immunol September 15, 2011, 187 (6) 3121-3132; DOI: https://doi.org/10.4049/jimmunol.1100378
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Development and Function of Innate Polyclonal TCRαβ⁺ CD8⁺ Thymocytes
Moutih Rafei, Marie-Pierre Hardy, Patrick Williams, Juan Ruiz Vanegas, Kathy-Ann Forner, Gaël Dulude, Nathalie Labrecque, Jacques Galipeau and Claude Perreault

J Immunol September 15, 2011, 187 (6) 3133-3144; DOI: https://doi.org/10.4049/jimmunol.1101097
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Multiple CD4⁺ T Cell Subsets Produce Immunomodulatory IL-10 During Respiratory Syncytial Virus Infection
Kayla A. Weiss, Allison F. Christiaansen, Ross B. Fulton, David K. Meyerholz and Steven M. Varga

J Immunol September 15, 2011, 187 (6) 3145-3154; DOI: https://doi.org/10.4049/jimmunol.1100764
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T Cell-Derived Act1 Is Necessary for IL-25–Mediated Th2 Responses and Allergic Airway Inflammation
Shadi Swaidani, Katarzyna Bulek, Zizhen Kang, Muhammet Fatih Gulen, Caini Liu, Weiguo Yin, Amina Abbadi, Mark Aronica and Xiaoxia Li

J Immunol September 15, 2011, 187 (6) 3155-3164; DOI: https://doi.org/10.4049/jimmunol.1002790
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Novel Highly Sensitive IL-10–β-Lactamase Reporter Mouse Reveals Cells of the Innate Immune System as a Substantial Source of IL-10 In Vivo
Hicham Bouabe, Yunying Liu, Markus Moser, Michael R. Bösl and Jürgen Heesemann

J Immunol September 15, 2011, 187 (6) 3165-3176; DOI: https://doi.org/10.4049/jimmunol.1101477
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Gαi2 and ZAP-70 Mediate RasGRP1 Membrane Localization and Activation of SDF-1–Induced T Cell Functions
Kimberly N. Kremer, Ashok Kumar and Karen E. Hedin

J Immunol September 15, 2011, 187 (6) 3177-3185; DOI: https://doi.org/10.4049/jimmunol.1100206
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Regulatory T Cells Selectively Control CD8⁺ T Cell Effector Pool Size via IL-2 Restriction
Wolfgang Kastenmuller, Georg Gasteiger, Naeha Subramanian, Tim Sparwasser, Dirk H. Busch, Yasmine Belkaid, Ingo Drexler and Ronald N. Germain

J Immunol September 15, 2011, 187 (6) 3186-3197; DOI: https://doi.org/10.4049/jimmunol.1101649

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Intra-Golgi Formation of IgM–Glycosaminoglycan Complexes Promotes Ig Deposition
Salar N. Khan, John V. Cox, Satoru K. Nishimoto, Ching Chen, Marvin J. Fritzler, Linda M. Hendershot, Martin Weigert and Marko Radic

J Immunol September 15, 2011, 187 (6) 3198-3207; DOI: https://doi.org/10.4049/jimmunol.1101336
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Structural Basis for FcγRIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes
Paul A. Ramsland, William Farrugia, Tessa M. Bradford, Caroline Tan Sardjono, Sandra Esparon, Halina M. Trist, Maree S. Powell, Peck Szee Tan, Angela C. Cendron, Bruce D. Wines, Andrew M. Scott and P. Mark Hogarth

J Immunol September 15, 2011, 187 (6) 3208-3217; DOI: https://doi.org/10.4049/jimmunol.1101467
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Nephrotic Syndrome and Subepithelial Deposits in a Mouse Model of Immune-Mediated Anti-Podocyte Glomerulonephritis
Catherine Meyer-Schwesinger, Silke Dehde, Philipp Klug, Jan U. Becker, Sabrina Mathey, Kazem Arefi, Stefan Balabanov, Simone Venz, Karl-Hans Endlich, Marcela Pekna, J. Engelbert Gessner, Friedrich Thaiss and Tobias N. Meyer

J Immunol September 15, 2011, 187 (6) 3218-3229; DOI: https://doi.org/10.4049/jimmunol.1003451
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Activation of TLR2 Enhances Tight Junction Barrier in Epidermal Keratinocytes
Takuo Yuki, Hiroyuki Yoshida, Yumiko Akazawa, Aya Komiya, Yoshinori Sugiyama and Shintaro Inoue

J Immunol September 15, 2011, 187 (6) 3230-3237; DOI: https://doi.org/10.4049/jimmunol.1100058
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Species-Specific Determinants in the IgG CH3 Domain Enable Fab-Arm Exchange by Affecting the Noncovalent CH3–CH3 Interaction Strength
Aran F. Labrijn, Theo Rispens, Joyce Meesters, Rebecca J. Rose, Tamara H. den Bleker, Stefan Loverix, Ewald T. J. van den Bremer, Joost Neijssen, Tom Vink, Ignace Lasters, Rob C. Aalberse, Albert J. R. Heck, Jan G. J. van de Winkel, Janine Schuurman and Paul W. H. I. Parren

J Immunol September 15, 2011, 187 (6) 3238-3246; DOI: https://doi.org/10.4049/jimmunol.1003336
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Separation of Mutational and Transcriptional Enhancers in Ig Genes
Naga Rama Kothapalli, Kaitlin M. Collura, Darrell D. Norton and Sebastian D. Fugmann

J Immunol September 15, 2011, 187 (6) 3247-3255; DOI: https://doi.org/10.4049/jimmunol.1101568
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Antioxidant c-FLIP Inhibits Fas Ligand-Induced NF-κB Activation in a Phosphatidylinositol 3-Kinase/Akt-Dependent Manner
Anand Krishnan V. Iyer, Neelam Azad, Siera Talbot, Christian Stehlik, Bin Lu, Liying Wang and Yon Rojanasakul

J Immunol September 15, 2011, 187 (6) 3256-3266; DOI: https://doi.org/10.4049/jimmunol.1002915
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Recognition of Class I MHC by a Rat Ly49 NK Cell Receptor Is Dependent on the Identity of the P2 Anchor Amino Acid of Bound Peptide
Brian J. Ma and Kevin P. Kane

J Immunol September 15, 2011, 187 (6) 3267-3276; DOI: https://doi.org/10.4049/jimmunol.1002809
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Differential Regulation of Proximal and Distal Vβ Segments Upstream of a Functional VDJβ1 Rearrangement upon β-Selection
Brenna L. Brady and Craig H. Bassing

J Immunol September 15, 2011, 187 (6) 3277-3285; DOI: https://doi.org/10.4049/jimmunol.1101079

IMMUNOGENETICS

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The CD6 Multiple Sclerosis Susceptibility Allele Is Associated with Alterations in CD4⁺ T Cell Proliferation
David M. Kofler, Christopher A. Severson, Narine Mousissian, Philip L. De Jager and David A. Hafler

J Immunol September 15, 2011, 187 (6) 3286-3291; DOI: https://doi.org/10.4049/jimmunol.1100626
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Two-Step Binding of Transcription Factors Causes Sequential Chromatin Structural Changes at the Activated IL-2 Promoter
Satoru Ishihara and Ronald H. Schwartz

J Immunol September 15, 2011, 187 (6) 3292-3299; DOI: https://doi.org/10.4049/jimmunol.1003173

HOST DEFENSE

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Mutations in a Dominant Nef Epitope of Simian Immunodeficiency Virus Diminish TCR:Epitope Peptide Affinity but not Epitope Peptide:MHC Class I Binding
Evan M. Cale, Heidi S. Bazick, Tony A. Rianprakaisang, S. Munir Alam and Norman L. Letvin

J Immunol September 15, 2011, 187 (6) 3300-3313; DOI: https://doi.org/10.4049/jimmunol.1101080
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The Transport and Inactivation Kinetics of Bacterial Lipopolysaccharide Influence Its Immunological Potency In Vivo
Mingfang Lu and Robert S. Munford

J Immunol September 15, 2011, 187 (6) 3314-3320; DOI: https://doi.org/10.4049/jimmunol.1004087
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B Cells and TCR Avidity Determine Distinct Functions of CD4⁺ T Cells in Retroviral Infection
Mickaël J.-Y. Ploquin, Urszula Eksmond and George Kassiotis

J Immunol September 15, 2011, 187 (6) 3321-3330; DOI: https://doi.org/10.4049/jimmunol.1101006

INFLAMMATION

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NLRP3/Caspase-1–Independent IL-1β Production Mediates Diesel Exhaust Particle-Induced Pulmonary Inflammation
Sharen Provoost, Tania Maes, Nele S. Pauwels, Tom Vanden Berghe, Peter Vandenabeele, Bart N. Lambrecht, Guy F. Joos and Kurt G. Tournoy

J Immunol September 15, 2011, 187 (6) 3331-3337; DOI: https://doi.org/10.4049/jimmunol.1004062
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Autoreactive Memory CD4⁺ T Lymphocytes That Mediate Chronic Uveitis Reside in the Bone Marrow through STAT3-Dependent Mechanisms
Hyun-Mee Oh, Cheng-Rong Yu, YongJun Lee, Chi-Chao Chan, Arvydas Maminishkis and Charles E. Egwuagu

J Immunol September 15, 2011, 187 (6) 3338-3346; DOI: https://doi.org/10.4049/jimmunol.1004019
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Cyclophilin A Is a Damage-Associated Molecular Pattern Molecule That Mediates Acetaminophen-Induced Liver Injury
James W. Dear, Kenneth J. Simpson, Melianthe P. J. Nicolai, James H. Catterson, Jonathan Street, Tineke Huizinga, Darren G. Craig, Kevin Dhaliwal, Sheila Webb, D. Nicholas Bateman and David J. Webb

J Immunol September 15, 2011, 187 (6) 3347-3352; DOI: https://doi.org/10.4049/jimmunol.1100165
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Membrane-Associated CD93 Regulates Leukocyte Migration and C1q-Hemolytic Activity during Murine Peritonitis
Mallary C. Greenlee-Wacker, Carlos Briseño, Manuel Galvan, Gabriela Moriel, Peter Velázquez and Suzanne S. Bohlson

J Immunol September 15, 2011, 187 (6) 3353-3361; DOI: https://doi.org/10.4049/jimmunol.1100803
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MicroRNA-21 Limits In Vivo Immune Response-Mediated Activation of the IL-12/IFN-γ Pathway, Th1 Polarization, and the Severity of Delayed-Type Hypersensitivity
Thomas X. Lu, Jochen Hartner, Eun-Jin Lim, Victoria Fabry, Melissa K. Mingler, Eric T. Cole, Stuart H. Orkin, Bruce J. Aronow and Marc E. Rothenberg

J Immunol September 15, 2011, 187 (6) 3362-3373; DOI: https://doi.org/10.4049/jimmunol.1101235
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MAPK Kinase 3 Specifically Regulates FcεRI-Mediated IL-4 Production by Mast Cells
Adam J. MacNeil, Yong Jun Yang and Tong-Jun Lin

J Immunol September 15, 2011, 187 (6) 3374-3382; DOI: https://doi.org/10.4049/jimmunol.1003126

CLINICAL IMMUNOLOGY

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Epidermal Growth Factor Receptor (EGFR) Antibody-Induced Antibody-Dependent Cellular Cytotoxicity Plays a Prominent Role in Inhibiting Tumorigenesis, Even of Tumor Cells Insensitive to EGFR Signaling Inhibition
Marije B. Overdijk, Sandra Verploegen, Jeroen H. van den Brakel, Jeroen J. Lammerts van Bueren, Tom Vink, Jan G. J. van de Winkel, Paul W. H. I. Parren and Wim K. Bleeker

J Immunol September 15, 2011, 187 (6) 3383-3390; DOI: https://doi.org/10.4049/jimmunol.1003926
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HIV-DNA Priming Alters T Cell Responses to HIV-Adenovirus Vaccine Even When Responses to DNA Are Undetectable
Stephen C. De Rosa, Evan P. Thomas, John Bui, Yunda Huang, Allan deCamp, Cecilia Morgan, Spyros A. Kalams, Georgia D. Tomaras, Rama Akondy, Rafi Ahmed, Chuen-Yen Lau, Barney S. Graham, Gary J. Nabel and M. Juliana McElrath

J Immunol September 15, 2011, 187 (6) 3391-3401; DOI: https://doi.org/10.4049/jimmunol.1101421
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IL-12p35 Subunit Contributes to Autoimmunity by Limiting IL-27–Driven Regulatory Responses
Rita Vasconcellos, Natalie A. Carter, Elizabeth C. Rosser and Claudia Mauri

J Immunol September 15, 2011, 187 (6) 3402-3412; DOI: https://doi.org/10.4049/jimmunol.1100224
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Activated Protein C Attenuates Systemic Lupus Erythematosus and Lupus Nephritis in MRL-Fas(lpr) Mice
Julia Lichtnekert, Khader Valli Rupanagudi, Onkar P. Kulkarni, Murthy Narayana Darisipudi, Ramanjaneyulu Allam and Hans-Joachim Anders

J Immunol September 15, 2011, 187 (6) 3413-3421; DOI: https://doi.org/10.4049/jimmunol.1101125
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Decreased AIRE Expression and Global Thymic Hypofunction in Down Syndrome
Flavia A. Lima, Carlos A. Moreira-Filho, Patrícia L. Ramos, Helena Brentani, Leandro de A. Lima, Magaly Arrais, Luiz C. Bento-de-Souza, Luciana Bento-de-Souza, Maria I. Duarte, Antonio Coutinho and Magda Carneiro-Sampaio

J Immunol September 15, 2011, 187 (6) 3422-3430; DOI: https://doi.org/10.4049/jimmunol.1003053
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Simvastatin Inhibits IFN Regulatory Factor 4 Expression and Th17 Cell Differentiation in CD4⁺ T Cells Derived from Patients with Multiple Sclerosis
Xin Zhang, Yazhong Tao, Luigi Troiani and Silva Markovic-Plese

J Immunol September 15, 2011, 187 (6) 3431-3437; DOI: https://doi.org/10.4049/jimmunol.1100580
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Loss of CD20 and Bound CD20 Antibody from Opsonized B Cells Occurs More Rapidly Because of Trogocytosis Mediated by Fc Receptor-Expressing Effector Cells Than Direct Internalization by the B Cells
Paul V. Beum, Elizabeth M. Peek, Margaret A. Lindorfer, Frank J. Beurskens, Patrick J. Engelberts, Paul W. H. I. Parren, Jan G. J. van de Winkel and Ronald P. Taylor

J Immunol September 15, 2011, 187 (6) 3438-3447; DOI: https://doi.org/10.4049/jimmunol.1101189

LETTERS OF RETRACTION

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Retraction: Stimulation of FcɣRI on Primary Sensory Neurons Increases Insulin-Like Growth Factor-I Production, Thereby Reducing Reperfusion-Induced Renal Injury in Mice
Naoaki Harada, Juan Zhao, Kenji Okajima, Hiroki Kurihara and Naomi Nakagata

J Immunol September 15, 2011, 187 (6) 3448; DOI: https://doi.org/10.4049/jimmunol.1190053

CORRECTIONS

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Correction: Salmonella Synthesizing 1-Monophosphorylated Lipopolysaccharide Exhibits Low Endotoxic Activity while Retaining Its Immunogenicity
Qingke Kong, David A. Six, Kenneth L. Roland, Qing Liu, Lillian Gu, C. Michael Reynolds, Xiaoyuan Wang, Christian R. H. Raetz and Roy Curtiss III

J Immunol September 15, 2011, 187 (6) 3449; DOI: https://doi.org/10.4049/jimmunol.1190051
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Correction: Slam Haplotypes Modulate the Response to Lipopolysaccharide In Vivo through Control of NKT Cell Number and Function
Idil Aktan, Alan Chant, Zachary D. Borg, David E. Damby, Paige C. Leenstra, Graham W. G. Lilley, Joseph Petty, Benjamin T. Suratt, Cory Teuscher, Edward K. Wakeland, Matthew E. Poynter and Jonathan E. Boyson

J Immunol September 15, 2011, 187 (6) 3450; DOI: https://doi.org/10.4049/jimmunol.1190052
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Correction: Th17 Cells Contribute to Viral Replication in Coxsackievirus B3-Induced Acute Viral Myocarditis
Jing Yuan, Miao Yu, Qiong-Wen Lin, Ai-Lin Cao, Xian Yu, Ji-Hua Dong, Jin-Ping Wang, Jing-Hui Zhang, Min Wang, He-Ping Guo, Xiang Cheng and Yu-Hua Liao

J Immunol September 15, 2011, 187 (6) 3451-3452; DOI: https://doi.org/10.4049/jimmunol.1190050

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IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

LETTERS OF RETRACTION

CORRECTIONS

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