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Mammalian Target of Rapamycin Inhibition in Macrophages of Asymptomatic HIV+ Persons Reverses the Decrease in TLR-4–Mediated TNF-α Release through Prolongation of MAPK Pathway Activation

Xin Li, Xinbing Han, Juliana Llano, Medhavi Bole, Xiuqin Zhou, Katharine Swan, Asha Anandaiah, Benjamin Nelson, Naimish R. Patel, Peter S. Reinach, Henry Koziel and Souvenir D. Tachado
J Immunol December 1, 2011, 187 (11) 6052-6058; DOI: https://doi.org/10.4049/jimmunol.1101532
Xin Li
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Xinbing Han
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Juliana Llano
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Medhavi Bole
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Xiuqin Zhou
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Katharine Swan
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Asha Anandaiah
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Benjamin Nelson
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Naimish R. Patel
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Peter S. Reinach
†Department of Biological Sciences, State University of New York, College of Optometry, New York, NY 10036
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Henry Koziel
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Souvenir D. Tachado
*Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
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Article Information

vol. 187 no. 11 6052-6058
DOI 
https://doi.org/10.4049/jimmunol.1101532
PubMed 
22025552

Published By 
The American Association of Immunologists, Inc.
Print ISSN 
0022-1767
Online ISSN 
1550-6606
History 
  • Received May 25, 2011
  • Accepted September 23, 2011
  • Published online November 18, 2011.

Article Versions

  • Older version (October 24, 2011 - 12:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2011 by The American Association of Immunologists, Inc.

Author Information

  1. Xin Li*,
  2. Xinbing Han*,
  3. Juliana Llano*,
  4. Medhavi Bole*,
  5. Xiuqin Zhou*,
  6. Katharine Swan*,
  7. Asha Anandaiah*,
  8. Benjamin Nelson*,
  9. Naimish R. Patel*,
  10. Peter S. Reinach†,
  11. Henry Koziel* and
  12. Souvenir D. Tachado*
  1. *Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215; and
  2. †Department of Biological Sciences, State University of New York, College of Optometry, New York, NY 10036
  1. Address correspondence and reprint requests to Dr. Souvenir D. Tachado, Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Dana Building, Room 652, Boston, MA 02215. E-mail address: stachado{at}bidmc.harvard.edu
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Article usage

Article usage: October 2011 to July 2022

AbstractFullPdf
Oct 2011455064
Nov 20117122584
Dec 20114304652
Total 2011159771200
Jan 20121554233
Feb 20121014030
Mar 2012802116
Apr 2012492028
May 2012492530
Jun 2012391514
Jul 201238917
Aug 2012361220
Sep 2012311525
Oct 201247822
Nov 2012231326
Dec 201234828
Total 2012682228289
Jan 2013402242
Feb 2013392632
Mar 2013301839
Apr 2013431938
May 2013241131
Jun 2013281330
Jul 2013231518
Aug 201315724
Sep 2013201626
Oct 2013301939
Nov 2013221341
Dec 201381329
Total 2013322192389
Jan 2014301434
Feb 2014241869
Mar 2014191363
Apr 2014281130
May 20146934
Jun 2014131344
Jul 2014203435
Aug 2014102725
Sep 2014113732
Oct 2014211622
Nov 201414827
Dec 20149817
Total 2014205208432
Jan 201519423
Feb 201561021
Mar 201527836
Apr 20154523
May 201514427
Jun 20154422
Jul 20158415
Aug 201511521
Sep 201513925
Oct 201520821
Nov 201521627
Dec 20156715
Total 201515374276
Jan 201616730
Feb 20164420
Mar 20162415
Apr 201611120
May 20168216
Jun 201611231
Jul 201613320
Aug 201611512
Sep 201611415
Oct 201620212
Nov 201616417
Dec 20168916
Total 201613147224
Jan 20174610
Feb 20170198
Mar 201701210
Apr 20171102
May 20170133
Jun 2017242
Jul 20170211
Aug 20171139
Sep 20171127
Oct 20171185
Nov 20175911
Dec 20170145
Total 20171515173
Jan 20181179
Feb 20181135
Mar 20183198
Apr 20180178
May 20182244
Jun 20180135
Jul 20181223
Aug 20180413
Sep 20181222
Oct 20180287
Nov 20181409
Dec 20180234
Total 20181027967
Jan 201942011
Feb 201921311
Mar 20190204
Apr 20191399
May 20190215
Jun 201902415
Jul 201971911
Aug 201911712
Sep 20190319
Oct 20190382
Nov 20190122
Dec 201941413
Total 201919268104
Jan 202041311
Feb 20200159
Mar 20206736
Apr 20206695
May 20200212
Jun 202011818
Jul 2020192
Aug 20201103
Sep 20201112
Oct 20202123
Nov 20202138
Dec 20202105
Total 20202627474
Jan 2021069
Feb 202111012
Mar 2021246
Apr 20211389
May 20218366
Jun 20211413
Jul 202105816
Aug 20211455
Sep 202115227
Oct 202104822
Nov 202106113
Dec 20211452
Total 202116444130
Jan 202213111
Feb 202225414
Mar 20222623
Apr 20220505
May 202214717
Jun 20220608
Jul 20220615
Total 2022636563
Total318226012321

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The Journal of Immunology: 187 (11)
The Journal of Immunology
Vol. 187, Issue 11
1 Dec 2011
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Mammalian Target of Rapamycin Inhibition in Macrophages of Asymptomatic HIV+ Persons Reverses the Decrease in TLR-4–Mediated TNF-α Release through Prolongation of MAPK Pathway Activation
Xin Li, Xinbing Han, Juliana Llano, Medhavi Bole, Xiuqin Zhou, Katharine Swan, Asha Anandaiah, Benjamin Nelson, Naimish R. Patel, Peter S. Reinach, Henry Koziel, Souvenir D. Tachado
The Journal of Immunology December 1, 2011, 187 (11) 6052-6058; DOI: 10.4049/jimmunol.1101532

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Mammalian Target of Rapamycin Inhibition in Macrophages of Asymptomatic HIV+ Persons Reverses the Decrease in TLR-4–Mediated TNF-α Release through Prolongation of MAPK Pathway Activation
Xin Li, Xinbing Han, Juliana Llano, Medhavi Bole, Xiuqin Zhou, Katharine Swan, Asha Anandaiah, Benjamin Nelson, Naimish R. Patel, Peter S. Reinach, Henry Koziel, Souvenir D. Tachado
The Journal of Immunology December 1, 2011, 187 (11) 6052-6058; DOI: 10.4049/jimmunol.1101532
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