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The Journal of Immunology

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Table of Contents

December 1, 2011; Volume 187,Issue 11

IN MEMORIAM

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    A Remembrance of Baruj Benacerraf (AAI '57) 1920–2011
    Ronald N. Germain and Steven J. Burakoff
    J Immunol December 1, 2011, 187 (11) 5465-5469; DOI: https://doi.org/10.4049/jimmunol.1190069

IN THIS ISSUE

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    In This Issue
    J Immunol December 1, 2011, 187 (11) 5471-5472; DOI: https://doi.org/10.4049/jimmunol.1190070

LETTERS TO THE EDITOR

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    Comment on “The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility”
    Kenneth G. C. Smith, Lisa C. Willcocks and Paul A. Lyons
    J Immunol December 1, 2011, 187 (11) 5473; DOI: https://doi.org/10.4049/jimmunol.1190065
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    Response to Comment on “The Inhibiting Fc Receptor for IgG, FcγRIIB, Is a Modifier of Autoimmune Susceptibility”
    Sjef Verbeek, Peter Boross and Shozo Izui
    J Immunol December 1, 2011, 187 (11) 5473-5474; DOI: https://doi.org/10.4049/jimmunol.1190066

PILLARS OF IMMUNOLOGY

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    Cytokine Signaling: Birth of a Pathway
    John J. O'Shea, Massimo Gadina and Yuka Kanno
    J Immunol December 1, 2011, 187 (11) 5475-5478; DOI: https://doi.org/10.4049/jimmunol.1102913
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    Pillars Article: A Protein Tyrosine Kinase in the Interferon α/β Signaling Pathway. Cell. 1992. 70: 313–322
    Laura Velazquez, Marc Fellous, George R. Stark and Sandra Pellegrini
    J Immunol December 1, 2011, 187 (11) 5479-5488;
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    Pillars Article: Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor. Science. 1992. 257: 809–813
    Chris Schindler, Ke Shuai, Vincent R. Prezioso and James E. Darnell Jr.
    J Immunol December 1, 2011, 187 (11) 5489-5494;

CUTTING EDGE

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    Cutting Edge: Nicastrin and Related Components of γ-Secretase Generate a Peptide Epitope Facilitating Immune Recognition of Intracellular Mycobacteria, through MHC Class II-Dependent Priming of T Cells
    Christopher R. Singh, Pearl Bakhru, Arshad Khan, Qing Bo Li and Chinnaswamy Jagannath
    J Immunol December 1, 2011, 187 (11) 5495-5499; DOI: https://doi.org/10.4049/jimmunol.1100521
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    Cutting Edge: Calcium/Calmodulin-Dependent Protein Kinase Type IV Is Essential for Mesangial Cell Proliferation and Lupus Nephritis
    Kunihiro Ichinose, Thomas Rauen, Yuang-Taung Juang, Katalin Kis-Toth, Masayuki Mizui, Tomohiro Koga and George C. Tsokos
    J Immunol December 1, 2011, 187 (11) 5500-5504; DOI: https://doi.org/10.4049/jimmunol.1102357
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    Cutting Edge: Natural Helper Cells Derive from Lymphoid Progenitors
    Qi Yang, Steven A. Saenz, Daniel A. Zlotoff, David Artis and Avinash Bhandoola
    J Immunol December 1, 2011, 187 (11) 5505-5509; DOI: https://doi.org/10.4049/jimmunol.1102039
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    Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection
    John R. Teijaro, Damian Turner, Quynh Pham, E. John Wherry, Leo Lefrançois and Donna L. Farber
    J Immunol December 1, 2011, 187 (11) 5510-5514; DOI: https://doi.org/10.4049/jimmunol.1102243
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    Cutting Edge: A Role for Inside-Out Signaling in TCR Regulation of CD28 Ligand Binding
    Mariano Sanchez-Lockhart, Minsoo Kim and Jim Miller
    J Immunol December 1, 2011, 187 (11) 5515-5519; DOI: https://doi.org/10.4049/jimmunol.1102497

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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    Altered Differentiation, Diminished Pathogenicity, and Regulatory Activity of Myelin-Specific T Cells Expressing an Enhanced Affinity TCR
    Rajshekhar Alli, Phuong Nguyen and Terrence L. Geiger
    J Immunol December 1, 2011, 187 (11) 5521-5531; DOI: https://doi.org/10.4049/jimmunol.1102202
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    Different Expression Levels of the TAP Peptide Transporter Lead to Recognition of Different Antigenic Peptides by Tumor-Specific CTL
    Aurélie Durgeau, Faten El Hage, Isabelle Vergnon, Pierre Validire, Vincent de Montpréville, Benjamin Besse, Jean-Charles Soria, Thorbald van Hall and Fathia Mami-Chouaib
    J Immunol December 1, 2011, 187 (11) 5532-5539; DOI: https://doi.org/10.4049/jimmunol.1102060
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    Virally-Induced Upregulation of Heparan Sulfate on B Cells via the Action of Type I IFN
    Nadine Jarousse, Damian L. Trujillo, Sarah Wilcox-Adelman and Laurent Coscoy
    J Immunol December 1, 2011, 187 (11) 5540-5547; DOI: https://doi.org/10.4049/jimmunol.1003495
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    The Antiviral Immune Response in Mice Devoid of Immunoproteasome Activity
    Michael Basler, Ulrike Beck, Christopher J. Kirk and Marcus Groettrup
    J Immunol December 1, 2011, 187 (11) 5548-5557; DOI: https://doi.org/10.4049/jimmunol.1101064
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    Coordinated Regulation of Lymph Node Vascular–Stromal Growth First by CD11c+ Cells and Then by T and B Cells
    Susan Chyou, Fairouz Benahmed, Jingfeng Chen, Varsha Kumar, Sha Tian, Martin Lipp and Theresa T. Lu
    J Immunol December 1, 2011, 187 (11) 5558-5567; DOI: https://doi.org/10.4049/jimmunol.1101724
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    Quantifying Antigen-Specific CD4 T Cells during a Viral Infection: CD4 T Cell Responses Are Larger Than We Think
    Daniel S. McDermott and Steven M. Varga
    J Immunol December 1, 2011, 187 (11) 5568-5576; DOI: https://doi.org/10.4049/jimmunol.1102104
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    CD84 Negatively Regulates IgE High-Affinity Receptor Signaling in Human Mast Cells
    Damiana Álvarez-Errico, Irene Oliver-Vila, Erola Ainsua-Enrich, Alasdair M. Gilfillan, César Picado, Joan Sayós and Margarita Martín
    J Immunol December 1, 2011, 187 (11) 5577-5586; DOI: https://doi.org/10.4049/jimmunol.1101626
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    Glycogen Synthase Kinase-3β Is a Prosurvival Signal for the Maintenance of Human Mast Cell Homeostasis
    Madeleine Rådinger, Daniel Smrž, Dean D. Metcalfe and Alasdair M. Gilfillan
    J Immunol December 1, 2011, 187 (11) 5587-5595; DOI: https://doi.org/10.4049/jimmunol.1101257
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    Negative Selection by IgM Superantigen Defines a B Cell Central Tolerance Compartment and Reveals Mutations Allowing Escape
    Bao Hoa Duong, Takayuki Ota, Miyo Aoki-Ota, Anthony Byron Cooper, Djemel Ait-Azzouzene, José Luis Vela, Amanda Lee Gavin and David Nemazee
    J Immunol December 1, 2011, 187 (11) 5596-5605; DOI: https://doi.org/10.4049/jimmunol.1102479
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    B7-H1 Expressed by Activated CD8 T Cells Is Essential for Their Survival
    Vesna Pulko, Kimberley J. Harris, Xin Liu, Rachel M. Gibbons, Susan M. Harrington, Christopher J. Krco, Eugene D. Kwon and Haidong Dong
    J Immunol December 1, 2011, 187 (11) 5606-5614; DOI: https://doi.org/10.4049/jimmunol.1003976
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    Human Th1 and Th17 Cells Exhibit Epigenetic Stability at Signature Cytokine and Transcription Factor Loci
    Carla J. Cohen, Sarah Q. Crome, Kate G. MacDonald, Elizabeth L. Dai, Dixie L. Mager and Megan K. Levings
    J Immunol December 1, 2011, 187 (11) 5615-5626; DOI: https://doi.org/10.4049/jimmunol.1101058
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    IL-1β and TGF-β Act Antagonistically in Induction and Differentially in Propagation of Human Proinflammatory Precursor CD4+ T Cells
    Katrin Hebel, Marion Rudolph, Bernhard Kosak, Hyun-Dong Chang, Jana Butzmann and Monika C. Brunner-Weinzierl
    J Immunol December 1, 2011, 187 (11) 5627-5635; DOI: https://doi.org/10.4049/jimmunol.1003998
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    Regulation of IFN-λ1 Promoter Activity (IFN-λ1/IL-29) in Human Airway Epithelial Cells
    Rachael Siegel, Joyce Eskdale and Grant Gallagher
    J Immunol December 1, 2011, 187 (11) 5636-5644; DOI: https://doi.org/10.4049/jimmunol.1003988
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    Cross-Talk Between TCR and CCR7 Signaling Sets a Temporal Threshold for Enhanced T Lymphocyte Migration
    Karin Schaeuble, Mark A. Hauser, Eva Singer, Marcus Groettrup and Daniel F. Legler
    J Immunol December 1, 2011, 187 (11) 5645-5652; DOI: https://doi.org/10.4049/jimmunol.1101850
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    Antimicrobial Peptides Inhibit Polyinosinic-Polycytidylic Acid-Induced Immune Responses
    Maroof Hasan, Catarina Ruksznis, Yan Wang and Cynthia Anne Leifer
    J Immunol December 1, 2011, 187 (11) 5653-5659; DOI: https://doi.org/10.4049/jimmunol.1102144
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    Pathogenic and Protective Functions of TNF in Neuroinflammation Are Defined by Its Expression in T Lymphocytes and Myeloid Cells
    Andrey A. Kruglov, Vicky Lampropoulou, Simon Fillatreau and Sergei A. Nedospasov
    J Immunol December 1, 2011, 187 (11) 5660-5670; DOI: https://doi.org/10.4049/jimmunol.1100663
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    Osteopontin Modulates the Generation of Memory CD8+ T Cells during Influenza Virus Infection
    Junko Morimoto, Kayoko Sato, Yosuke Nakayama, Chiemi Kimura, Kiichi Kajino, Yutaka Matsui, Tadaaki Miyazaki and Toshimitsu Uede
    J Immunol December 1, 2011, 187 (11) 5671-5683; DOI: https://doi.org/10.4049/jimmunol.1101825
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    Immune Regulation through Mitochondrion-Dependent Dendritic Cell Death Induced by T Regulatory Cells
    Min Chen, Kumar Felix and Jin Wang
    J Immunol December 1, 2011, 187 (11) 5684-5692; DOI: https://doi.org/10.4049/jimmunol.1101834
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    Proliferating Cell Nuclear Antigen Is a Novel Inhibitory Ligand for the Natural Cytotoxicity Receptor NKp44
    Benyamin Rosental, Michael Brusilovsky, Uzi Hadad, Dafna Oz, Michael Y. Appel, Fabian Afergan, Rami Yossef, Lior Ann Rosenberg, Amir Aharoni, Adelheid Cerwenka, Kerry S. Campbell, Alex Braiman and Angel Porgador
    J Immunol December 1, 2011, 187 (11) 5693-5702; DOI: https://doi.org/10.4049/jimmunol.1102267
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    A Critical Role for Macrophages in Promotion of Urethane-Induced Lung Carcinogenesis
    Rinat Zaynagetdinov, Taylor P. Sherrill, Vasiliy V. Polosukhin, Wei Han, Jamie A. Ausborn, Allyson G. McLoed, Frank B. McMahon, Linda A. Gleaves, Amber L. Degryse, Georgios T. Stathopoulos, Fiona E. Yull and Timothy S. Blackwell
    J Immunol December 1, 2011, 187 (11) 5703-5711; DOI: https://doi.org/10.4049/jimmunol.1100558
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    Formation of B-1 B Cells from Neonatal B-1 Transitional Cells Exhibits NF-κB Redundancy
    Encarnacion Montecino-Rodriguez and Kenneth Dorshkind
    J Immunol December 1, 2011, 187 (11) 5712-5719; DOI: https://doi.org/10.4049/jimmunol.1102416
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    Cannabinoid Receptor 2 Is Critical for the Homing and Retention of Marginal Zone B Lineage Cells and for Efficient T-Independent Immune Responses
    Sreemanti Basu, Avijit Ray and Bonnie N. Dittel
    J Immunol December 1, 2011, 187 (11) 5720-5732; DOI: https://doi.org/10.4049/jimmunol.1102195
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    Affinity Thresholds for Naive CD8+ CTL Activation by Peptides and Engineered Influenza A Viruses
    Alice E. Denton, Robb Wesselingh, Stephanie Gras, Carole Guillonneau, Matthew R. Olson, Justine D. Mintern, Weiguang Zeng, David C. Jackson, Jamie Rossjohn, Philip D. Hodgkin, Peter C. Doherty and Stephen J. Turner
    J Immunol December 1, 2011, 187 (11) 5733-5744; DOI: https://doi.org/10.4049/jimmunol.1003937
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    Influence of Galectin-9/Tim-3 Interaction on Herpes Simplex Virus-1 Latency
    Pradeep B. J. Reddy, Sharvan Sehrawat, Amol Suryawanshi, Naveen K. Rajasagi, Sachin Mulik, Mitsuomi Hirashima and Barry T. Rouse
    J Immunol December 1, 2011, 187 (11) 5745-5755; DOI: https://doi.org/10.4049/jimmunol.1102105
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    Rapamycin Attenuates Airway Hyperreactivity, Goblet Cells, and IgE in Experimental Allergic Asthma
    Elizabeth M. Mushaben, Elizabeth L. Kramer, Eric B. Brandt, Gurjit K. Khurana Hershey and Timothy D. Le Cras
    J Immunol December 1, 2011, 187 (11) 5756-5763; DOI: https://doi.org/10.4049/jimmunol.1102133
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    IL-6 Promotes Cardiac Graft Rejection Mediated by CD4+ Cells
    Adam Jared Booth, Svetlana Grabauskiene, Sherri Chan Wood, Guanyi Lu, Bryna E. Burrell and D. Keith Bishop
    J Immunol December 1, 2011, 187 (11) 5764-5771; DOI: https://doi.org/10.4049/jimmunol.1100766
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    A p53 Defect Sensitizes Various Stages of B Cell Development to Lymphomagenesis in Mice Carrying an IgH 3′ Regulatory Region-Driven c-myc Transgene
    Rémi Fiancette, Pauline Rouaud, Christelle Vincent-Fabert, Brice Laffleur, Virginie Magnone, Michel Cogné and Yves Denizot
    J Immunol December 1, 2011, 187 (11) 5772-5782; DOI: https://doi.org/10.4049/jimmunol.1102059
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    PTEN Negatively Regulates Engulfment of Apoptotic Cells by Modulating Activation of Rac GTPase
    Subhanjan Mondal, Saurabh Ghosh-Roy, Fabien Loison, Yitang Li, Yonghui Jia, Chad Harris, David A. Williams and Hongbo R. Luo
    J Immunol December 1, 2011, 187 (11) 5783-5794; DOI: https://doi.org/10.4049/jimmunol.1100484
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    Lineage−Sca1+c-Kit−CD25+ Cells Are IL-33–Responsive Type 2 Innate Cells in the Mouse Bone Marrow
    Adipong Brickshawana, Virginia Smith Shapiro, Hirohito Kita and Larry R. Pease
    J Immunol December 1, 2011, 187 (11) 5795-5804; DOI: https://doi.org/10.4049/jimmunol.1102242
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    C5a Regulates NKT and NK Cell Functions in Sepsis
    Michael E. Fusakio, Javid P. Mohammed, Yves Laumonnier, Kasper Hoebe, Jörg Köhl and Jochen Mattner
    J Immunol December 1, 2011, 187 (11) 5805-5812; DOI: https://doi.org/10.4049/jimmunol.1100338
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    Peptidoglycan Recognition Protein Pglyrp2 Protects Mice from Psoriasis-like Skin Inflammation by Promoting Regulatory T Cells and Limiting Th17 Responses
    Shin Yong Park, Dipika Gupta, Risa Hurwich, Chang H. Kim and Roman Dziarski
    J Immunol December 1, 2011, 187 (11) 5813-5823; DOI: https://doi.org/10.4049/jimmunol.1101068
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    Paxillin Associates with the Microtubule Cytoskeleton and the Immunological Synapse of CTL through Its Leucine-Aspartic Acid Domains and Contributes to Microtubule Organizing Center Reorientation
    Leslie K. Robertson and Hanne L. Ostergaard
    J Immunol December 1, 2011, 187 (11) 5824-5833; DOI: https://doi.org/10.4049/jimmunol.1003690
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    Selective Upregulation of microRNA Expression in Peripheral Blood Leukocytes in IL-10−/− Mice Precedes Expression in the Colon
    Jeremy S. Schaefer, Dina Montufar-Solis, Nadarajah Vigneswaran and John R. Klein
    J Immunol December 1, 2011, 187 (11) 5834-5841; DOI: https://doi.org/10.4049/jimmunol.1100922
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    Uric Acid-Driven Th17 Differentiation Requires Inflammasome-Derived IL-1 and IL-18
    Cristina Conforti-Andreoni, Roberto Spreafico, Hong Liang Qian, Nicolas Riteau, Bernhard Ryffel, Paola Ricciardi-Castagnoli and Alessandra Mortellaro
    J Immunol December 1, 2011, 187 (11) 5842-5850; DOI: https://doi.org/10.4049/jimmunol.1101408
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    α9β1 Integrin-Mediated Signaling Serves as an Intrinsic Regulator of Pathogenic Th17 Cell Generation
    Masashi Kanayama, Junko Morimoto, Yutaka Matsui, Masahiro Ikesue, Keiko Danzaki, Daisuke Kurotaki, Koyu Ito, Toshimichi Yoshida and Toshimitsu Uede
    J Immunol December 1, 2011, 187 (11) 5851-5864; DOI: https://doi.org/10.4049/jimmunol.1101524
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    CpG Protects Human Monocytic Cells against HIV-Vpr–Induced Apoptosis by Cellular Inhibitor of Apoptosis-2 through the Calcium-Activated JNK Pathway in a TLR9-Independent Manner
    Mansi Saxena, Aurelia Busca, Sunita Pandey, Marko Kryworuchko and Ashok Kumar
    J Immunol December 1, 2011, 187 (11) 5865-5878; DOI: https://doi.org/10.4049/jimmunol.1100115
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    Microbiota Downregulates Dendritic Cell Expression of miR-10a, Which Targets IL-12/IL-23p40
    Xiaochang Xue, Ting Feng, Suxia Yao, Kyle J. Wolf, Chang-Gong Liu, Xiuping Liu, Charles O. Elson and Yingzi Cong
    J Immunol December 1, 2011, 187 (11) 5879-5886; DOI: https://doi.org/10.4049/jimmunol.1100535
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    Cofilin-Mediated F-Actin Severing Is Regulated by the Rap GTPase and Controls the Cytoskeletal Dynamics That Drive Lymphocyte Spreading and BCR Microcluster Formation
    Spencer A. Freeman, Victor Lei, May Dang-Lawson, Kensaku Mizuno, Calvin D. Roskelley and Michael R. Gold
    J Immunol December 1, 2011, 187 (11) 5887-5900; DOI: https://doi.org/10.4049/jimmunol.1102233
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    Pancreatic Islets Engineered with SA-FasL Protein Establish Robust Localized Tolerance by Inducing Regulatory T Cells in Mice
    Esma S. Yolcu, Hong Zhao, Laura Bandura-Morgan, Chantale Lacelle, Kyle B. Woodward, Nadir Askenasy and Haval Shirwan
    J Immunol December 1, 2011, 187 (11) 5901-5909; DOI: https://doi.org/10.4049/jimmunol.1003266

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Escape from CD8+ T Cell Response by Natural Variants of an Immunodominant Epitope from Theileria parva Is Predominantly Due to Loss of TCR Recognition
    Timothy K. Connelley, Niall D. MacHugh, Roger Pelle, William Weir and W. Ivan Morrison
    J Immunol December 1, 2011, 187 (11) 5910-5920; DOI: https://doi.org/10.4049/jimmunol.1102009
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    Structure-Based Selection of Small Molecules To Alter Allele-Specific MHC Class II Antigen Presentation
    Aaron W. Michels, David A. Ostrov, Li Zhang, Maki Nakayama, Masanori Fuse, Kristen McDaniel, Bart O. Roep, Peter A. Gottlieb, Mark A. Atkinson and George S. Eisenbarth
    J Immunol December 1, 2011, 187 (11) 5921-5930; DOI: https://doi.org/10.4049/jimmunol.1100746
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    TOX Is Required for Development of the CD4 T Cell Lineage Gene Program
    Parinaz Aliahmad, Asha Kadavallore, Brian de la Torre, Dietmar Kappes and Jonathan Kaye
    J Immunol December 1, 2011, 187 (11) 5931-5940; DOI: https://doi.org/10.4049/jimmunol.1101474
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    SAP-Mediated Inhibition of Diacylglycerol Kinase α Regulates TCR-Induced Diacylglycerol Signaling
    Gianluca Baldanzi, Andrea Pighini, Valentina Bettio, Elena Rainero, Sara Traini, Federica Chianale, Paolo E. Porporato, Nicoletta Filigheddu, Riccardo Mesturini, Shuping Song, Tamas Schweighoffer, Laura Patrussi, Cosima T. Baldari, Xiao-Ping Zhong, Wim J. van Blitterswijk, Fabiola Sinigaglia, Kim E. Nichols, Ignacio Rubio, Ornella Parolini and Andrea Graziani
    J Immunol December 1, 2011, 187 (11) 5941-5951; DOI: https://doi.org/10.4049/jimmunol.1002476
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    The Actin Regulatory Protein HS1 Is Required for Antigen Uptake and Presentation by Dendritic Cells
    Yanping Huang, Chhanda Biswas, Deborah A. Klos Dehring, Uma Sriram, Edward K. Williamson, Shuixing Li, Fiona Clarke, Stefania Gallucci, Yair Argon and Janis K. Burkhardt
    J Immunol December 1, 2011, 187 (11) 5952-5963; DOI: https://doi.org/10.4049/jimmunol.1100870
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    T Cell Factor 1 Regulates Thymocyte Survival via a RORγt-Dependent Pathway
    Ruiqing Wang, Huimin Xie, Zhaofeng Huang, Jian Ma, Xianfeng Fang, Yan Ding and Zuoming Sun
    J Immunol December 1, 2011, 187 (11) 5964-5973; DOI: https://doi.org/10.4049/jimmunol.1101205
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    c-Myb and GATA-3 Cooperatively Regulate IL-13 Expression via Conserved GATA-3 Response Element and Recruit Mixed Lineage Leukemia (MLL) for Histone Modification of the IL-13 Locus
    Teruhiko Kozuka, Mayumi Sugita, Susan Shetzline, Alan M. Gewirtz and Yuji Nakata
    J Immunol December 1, 2011, 187 (11) 5974-5982; DOI: https://doi.org/10.4049/jimmunol.1100550
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    EphB Receptors Trigger Akt Activation and Suppress Fas Receptor-Induced Apoptosis in Malignant T Lymphocytes
    Alison Maddigan, Luke Truitt, Ryan Arsenault, Tanya Freywald, Odette Allonby, Jonathan Dean, Aru Narendran, Jim Xiang, Andrew Weng, Scott Napper and Andrew Freywald
    J Immunol December 1, 2011, 187 (11) 5983-5994; DOI: https://doi.org/10.4049/jimmunol.1003482

IMMUNOGENETICS

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    A Comparative Analysis of Viral Peptides Presented by Contemporary Human and Chimpanzee MHC Class I Molecules
    Hanneke W. M. van Deutekom, Ilka Hoof, Ronald E. Bontrop and Can Keşmir
    J Immunol December 1, 2011, 187 (11) 5995-6001; DOI: https://doi.org/10.4049/jimmunol.1102236

HOST DEFENSE

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    Phagosomal Degradation Increases TLR Access to Bacterial Ligands and Enhances Macrophage Sensitivity to Bacteria
    Andrea J. Wolf, Andrea Arruda, Christopher N. Reyes, Amber T. Kaplan, Takahiro Shimada, Kenichi Shimada, Moshe Arditi, George Liu and David M. Underhill
    J Immunol December 1, 2011, 187 (11) 6002-6010; DOI: https://doi.org/10.4049/jimmunol.1100232
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    Lung CD103+ Dendritic Cells Efficiently Transport Influenza Virus to the Lymph Node and Load Viral Antigen onto MHC Class I for Presentation to CD8 T Cells
    Adrian W. S. Ho, Nayana Prabhu, Richard John Betts, Moyar Qing Ge, Xilei Dai, Paul Edward Hutchinson, Fei Chuin Lew, Kok Loon Wong, Brendon John Hanson, Paul A. Macary and David Michael Kemeny
    J Immunol December 1, 2011, 187 (11) 6011-6021; DOI: https://doi.org/10.4049/jimmunol.1100987
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    Recruited Macrophages Control Dissemination of Group A Streptococcus from Infected Soft Tissues
    Inbal Mishalian, Merav Ordan, Amnon Peled, Alexander Maly, Miriam B. Eichenbaum, Miriam Ravins, Tegest Aychek, Steffen Jung and Emanuel Hanski
    J Immunol December 1, 2011, 187 (11) 6022-6031; DOI: https://doi.org/10.4049/jimmunol.1101385
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    Characterization of a Human Cervical CD4+ T Cell Subset Coexpressing Multiple Markers of HIV Susceptibility
    Lyle R. McKinnon, Billy Nyanga, Duncan Chege, Preston Izulla, Makobu Kimani, Sanja Huibner, Lawrence Gelmon, Katharine E. Block, Claudia Cicala, A. Omu Anzala, James Arthos, Joshua Kimani and Rupert Kaul
    J Immunol December 1, 2011, 187 (11) 6032-6042; DOI: https://doi.org/10.4049/jimmunol.1101836

INFLAMMATION

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    Hck Tyrosine Kinase Regulates TLR4-Induced TNF and IL-6 Production via AP-1
    Maria J. Smolinska, Theresa H. Page, Ania M. Urbaniak, Brenda E. Mutch and Nicole J. Horwood
    J Immunol December 1, 2011, 187 (11) 6043-6051; DOI: https://doi.org/10.4049/jimmunol.1100967
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    Mammalian Target of Rapamycin Inhibition in Macrophages of Asymptomatic HIV+ Persons Reverses the Decrease in TLR-4–Mediated TNF-α Release through Prolongation of MAPK Pathway Activation
    Xin Li, Xinbing Han, Juliana Llano, Medhavi Bole, Xiuqin Zhou, Katharine Swan, Asha Anandaiah, Benjamin Nelson, Naimish R. Patel, Peter S. Reinach, Henry Koziel and Souvenir D. Tachado
    J Immunol December 1, 2011, 187 (11) 6052-6058; DOI: https://doi.org/10.4049/jimmunol.1101532
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    Eosinophils Regulate Dendritic Cells and Th2 Pulmonary Immune Responses following Allergen Provocation
    Elizabeth A. Jacobsen, Katie R. Zellner, Dana Colbert, Nancy A. Lee and James J. Lee
    J Immunol December 1, 2011, 187 (11) 6059-6068; DOI: https://doi.org/10.4049/jimmunol.1102299
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    Mapping the Transcriptional Machinery of the IL-8 Gene in Human Bronchial Epithelial Cells
    Valentino Bezzerri, Monica Borgatti, Alessia Finotti, Anna Tamanini, Roberto Gambari and Giulio Cabrini
    J Immunol December 1, 2011, 187 (11) 6069-6081; DOI: https://doi.org/10.4049/jimmunol.1100821
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    Attenuated Atherosclerotic Lesions in apoE-Fcγ–Chain-Deficient Hyperlipidemic Mouse Model Is Associated with Inhibition of Th17 Cells and Promotion of Regulatory T Cells
    Hang Pong Ng, Ramona L. Burris and Shanmugam Nagarajan
    J Immunol December 1, 2011, 187 (11) 6082-6093; DOI: https://doi.org/10.4049/jimmunol.1004133
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    Integrin αvβ5-Mediated TGF-β Activation by Airway Smooth Muscle Cells in Asthma
    Amanda L. Tatler, Alison E. John, Lisa Jolly, Anthony Habgood, Jo Porte, Chris Brightling, Alan J. Knox, Linhua Pang, Dean Sheppard, Xiaozhu Huang and Gisli Jenkins
    J Immunol December 1, 2011, 187 (11) 6094-6107; DOI: https://doi.org/10.4049/jimmunol.1003507
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    The Role for Decorin in Delayed-Type Hypersensitivity
    Daniela G. Seidler, Negia A. Mohamed, Carla Bocian, Anika Stadtmann, Sven Hermann, Klaus Schäfers, Michael Schäfers, Renato V. Iozzo, Alexander Zarbock and Martin Götte
    J Immunol December 1, 2011, 187 (11) 6108-6119; DOI: https://doi.org/10.4049/jimmunol.1100373
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    Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
    Sergey Ryzhov, Sergey V. Novitskiy, Anna E. Goldstein, Asel Biktasova, Michael R. Blackburn, Italo Biaggioni, Mikhail M. Dikov and Igor Feoktistov
    J Immunol December 1, 2011, 187 (11) 6120-6129; DOI: https://doi.org/10.4049/jimmunol.1101225

CLINICAL IMMUNOLOGY

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    Pilot Clinical Trial of Type 1 Dendritic Cells Loaded with Autologous Tumor Lysates Combined with GM-CSF, Pegylated IFN, and Cyclophosphamide for Metastatic Cancer Patients
    Carlos Alfaro, Jose L. Perez-Gracia, Natalia Suarez, Javier Rodriguez, Miguel Fernandez de Sanmamed, Bruno Sangro, Salvador Martin-Algarra, Alfonso Calvo, Miriam Redrado, Alice Agliano, Alvaro Gonzalez, Inmaculada Rodriguez, Elixabet Bolaños, Sandra Hervás-Stubbs, Javier Perez-Calvo, Alberto Benito, Ivan Peñuelas, Carmen Vigil, José Richter, Ivan Martinez-Forero and Ignacio Melero
    J Immunol December 1, 2011, 187 (11) 6130-6142; DOI: https://doi.org/10.4049/jimmunol.1102209
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    Inflammasome Activation of IL-18 Results in Endothelial Progenitor Cell Dysfunction in Systemic Lupus Erythematosus
    J. Michelle Kahlenberg, Seth G. Thacker, Celine C. Berthier, Clemens D. Cohen, Matthias Kretzler and Mariana J. Kaplan
    J Immunol December 1, 2011, 187 (11) 6143-6156; DOI: https://doi.org/10.4049/jimmunol.1101284

CORRECTIONS

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    Correction: Distinct Roles of IL-23 and IL-17 in the Development of Psoriasis-Like Lesions in a Mouse Model
    Kimiko Nakajima, Takashi Kanda, Mikiro Takaishi, Takeo Shiga, Ken Miyoshi, Hideki Nakajima, Reiko Kamijima, Masahito Tarutani, Jacqueline M. Benson, M. Merle Elloso, Lester L. Gutshall, Michael F. Naso, Yoichiro Iwakura, John DiGiovanni and Shigetoshi Sano
    J Immunol December 1, 2011, 187 (11) 6157-6158; DOI: https://doi.org/10.4049/jimmunol.1190071
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    Correction: Basophils Amplify Type 2 Immune Responses, but Do Not Serve a Protective Role, during Chronic Infection of Mice with the Filarial Nematode Litomosoides sigmodontis
    Marina N. Torrero, Marc P. Hübner, David Larson, Hajime Karasuyama and Edward Mitre
    J Immunol December 1, 2011, 187 (11) 6159; DOI: https://doi.org/10.4049/jimmunol.1190061
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    Correction: TNF Mediates the Sustained Activation of Nrf2 in Human Monocytes
    Stuart A. Rushworth, Suharsh Shah and David J. MacEwan
    J Immunol December 1, 2011, 187 (11) 6160; DOI: https://doi.org/10.4049/jimmunol.1190072
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The Journal of Immunology: 187 (11)
The Journal of Immunology
Vol. 187, Issue 11
1 Dec 2011
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  • IN MEMORIAM
  • IN THIS ISSUE
  • LETTERS TO THE EDITOR
  • PILLARS OF IMMUNOLOGY
  • CUTTING EDGE
  • CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • IMMUNOGENETICS
  • HOST DEFENSE
  • INFLAMMATION
  • CLINICAL IMMUNOLOGY
  • CORRECTIONS
  • Highlights
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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