The Journal of Immunology: 186 (3)

February 1, 2011; Volume 186,Issue 3

IN THIS ISSUE

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In This Issue
J Immunol February 1, 2011, 186 (3) 1295-1296; DOI: https://doi.org/10.4049/jimmunol.1090128

LETTERS TO THE EDITOR

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Comment on “Type 1 Diabetes in BioBreeding Rats Is Critically Linked to an Imbalance between Th17 and Regulatory T Cells and an Altered TCR Repertoire”
Jan-Luuk Hillebrands, Jan Rozing and Jeroen T. J. Visser

J Immunol February 1, 2011, 186 (3) 1297-1298; DOI: https://doi.org/10.4049/jimmunol.1090132
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Response to Comment on “Type 1 Diabetes in BioBreeding Rats Is Critically Linked to an Imbalance between Th17 and Regulatory T Cells and an Altered TCR Repertoire”
Jens van den Brandt and Holger M. Reichardt

J Immunol February 1, 2011, 186 (3) 1298-1299; DOI: https://doi.org/10.4049/jimmunol.1090133
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Comment on “Flagellin as an Adjuvant: Cellular Mechanisms and Potential”
Janardan P. Pandey

J Immunol February 1, 2011, 186 (3) 1299; DOI: https://doi.org/10.4049/jimmunol.1090134
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Response to Comment on “Flagellin as an Adjuvant: Cellular Mechanisms and Potential”
Steven B. Mizel and John T. Bates

J Immunol February 1, 2011, 186 (3) 1299; DOI: https://doi.org/10.4049/jimmunol.1090135

PILLARS OF IMMUNOLOGY

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Receptor Editing as a Mechanism of B Cell Tolerance
Selvakumar Sukumar and Mark S. Schlissel

J Immunol February 1, 2011, 186 (3) 1301-1302; DOI: https://doi.org/10.4049/jimmunol.1090129
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Pillars Article: Receptor Editing: An Approach by Autoreactive B Cells to Escape Tolerance. The Journal of Experimental Medicine. 1993. 177: 999–1008
Denise Gay, Thomas Saunders, Sally Camper and Martin Weigert

J Immunol February 1, 2011, 186 (3) 1303-1312;
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Pillars Article: Receptor Editing in Self-reactive Bone Marrow B Cells. The Journal of Experimental Medicine. 1993. 177: 1009–1020
Susan L. Tiegs, David M. Russell and David Nemazee

J Immunol February 1, 2011, 186 (3) 1313-1324;

BRIEF REVIEWS

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Recent Developments in Cancer Vaccines
Karolina Palucka, Hideki Ueno and Jacques Banchereau

J Immunol February 1, 2011, 186 (3) 1325-1331; DOI: https://doi.org/10.4049/jimmunol.0902539

CUTTING EDGE

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Cutting Edge: NLRC5-Dependent Activation of the Inflammasome
Beckley K. Davis, Reid A. Roberts, Max T. Huang, Stephen B. Willingham, Brian J. Conti, W. June Brickey, Brianne R. Barker, Mildred Kwan, Debra J. Taxman, Mary-Ann Accavitti-Loper, Joseph A. Duncan and Jenny P.-Y. Ting

J Immunol February 1, 2011, 186 (3) 1333-1337; DOI: https://doi.org/10.4049/jimmunol.1003111
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Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions
Nicole Joller, Jason P. Hafler, Boel Brynedal, Nasim Kassam, Silvia Spoerl, Steven D. Levin, Arlene H. Sharpe and Vijay K. Kuchroo

J Immunol February 1, 2011, 186 (3) 1338-1342; DOI: https://doi.org/10.4049/jimmunol.1003081

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Postselection Thymocyte Maturation and Emigration Are Independent of IL-7 and ERK5
Michael A. Weinreich, Stephen C. Jameson and Kristin A. Hogquist

J Immunol February 1, 2011, 186 (3) 1343-1347; DOI: https://doi.org/10.4049/jimmunol.1002238
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Diverse Endogenous Antigens for Mouse NKT Cells: Self-Antigens That Are Not Glycosphingolipids
Bo Pei, Anneliese O. Speak, Dawn Shepherd, Terry Butters, Vincenzo Cerundolo, Frances M. Platt and Mitchell Kronenberg

J Immunol February 1, 2011, 186 (3) 1348-1360; DOI: https://doi.org/10.4049/jimmunol.1001008
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Concurrent Allorecognition Has a Limited Impact on Posttransplant Vaccination
Teresa Manzo, Rodrigo Hess Michelini, Veronica Basso, Alessia Ricupito, Jian-Guo Chai, Elizabeth Simpson, Matteo Bellone and Anna Mondino

J Immunol February 1, 2011, 186 (3) 1361-1368; DOI: https://doi.org/10.4049/jimmunol.1002030
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Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages
Yin Xia, Virna Cortez-Retamozo, Vera Niederkofler, Rishard Salie, Shanzhuo Chen, Tarek A. Samad, Charles C. Hong, Silvia Arber, Jatin M. Vyas, Ralph Weissleder, Mikael J. Pittet and Herbert Y. Lin

J Immunol February 1, 2011, 186 (3) 1369-1376; DOI: https://doi.org/10.4049/jimmunol.1002047
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Langerin⁺ Dermal Dendritic Cells Are Critical for CD8⁺ T Cell Activation and IgH γ-1 Class Switching in Response to Gene Gun Vaccines
Angelika Stoecklinger, Tekalign D. Eticha, Mehrnaz Mesdaghi, Adrien Kissenpfennig, Bernard Malissen, Josef Thalhamer and Peter Hammerl

J Immunol February 1, 2011, 186 (3) 1377-1383; DOI: https://doi.org/10.4049/jimmunol.1002557
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Epigenetic Reduction in Invariant NKT Cells following In Utero Vitamin D Deficiency in Mice
Sanhong Yu and Margherita T. Cantorna

J Immunol February 1, 2011, 186 (3) 1384-1390; DOI: https://doi.org/10.4049/jimmunol.1002545
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Glycogen Synthase Kinase-3 Is an Early Determinant in the Differentiation of Pathogenic Th17 Cells
Eléonore Beurel, Wen-I Yeh, Suzanne M. Michalek, Laurie E. Harrington and Richard S. Jope

J Immunol February 1, 2011, 186 (3) 1391-1398; DOI: https://doi.org/10.4049/jimmunol.1003511
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A Unique Role of the Cholera Toxin A1-DD Adjuvant for Long-Term Plasma and Memory B Cell Development
Mats Bemark, Peter Bergqvist, Anneli Stensson, Anna Holmberg, Johan Mattsson and Nils Y. Lycke

J Immunol February 1, 2011, 186 (3) 1399-1410; DOI: https://doi.org/10.4049/jimmunol.1002881
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CCL20 and β-Defensin-2 Induce Arrest of Human Th17 Cells on Inflamed Endothelium In Vitro under Flow Conditions
Soufiane Ghannam, Cécile Dejou, Nathalie Pedretti, Jean-Philipe Giot, Karim Dorgham, Hassan Boukhaddaoui, Virginie Deleuze, François-Xavier Bernard, Christian Jorgensen, Hans Yssel and Jérôme Pène

J Immunol February 1, 2011, 186 (3) 1411-1420; DOI: https://doi.org/10.4049/jimmunol.1000597
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Functional Redundancy between Thymic CD8α⁺ and Sirpα⁺ Conventional Dendritic Cells in Presentation of Blood-Derived Lysozyme by MHC Class II Proteins
Danielle F. Atibalentja, Kenneth M. Murphy and Emil R. Unanue

J Immunol February 1, 2011, 186 (3) 1421-1431; DOI: https://doi.org/10.4049/jimmunol.1002587
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CD1d-Restricted IFN-γ–Secreting NKT Cells Promote Immune Complex-Induced Acute Lung Injury by Regulating Macrophage-Inflammatory Protein-1α Production and Activation of Macrophages and Dendritic Cells
Ji Hyung Kim and Doo Hyun Chung

J Immunol February 1, 2011, 186 (3) 1432-1441; DOI: https://doi.org/10.4049/jimmunol.1003140
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Transplantation Tolerance to a Single Noninherited MHC Class I Maternal Alloantigen Studied in a TCR-Transgenic Mouse Model
Yoshinobu Akiyama, Stéphane M. Caucheteux, Cécile Vernochet, Yoshiko Iwamoto, Katsunori Tanaka, Colette Kanellopoulos-Langevin and Gilles Benichou

J Immunol February 1, 2011, 186 (3) 1442-1449; DOI: https://doi.org/10.4049/jimmunol.1003023
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Runx1/Cbfβ2 Complexes Are Required for Lymphoid Tissue Inducer Cell Differentiation at Two Developmental Stages
Masashi Tachibana, Mari Tenno, Chieko Tezuka, Machiko Sugiyama, Hisahiro Yoshida and Ichiro Taniuchi

J Immunol February 1, 2011, 186 (3) 1450-1457; DOI: https://doi.org/10.4049/jimmunol.1000162
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IFN Regulatory Factor 8 Restricts the Size of the Marginal Zone and Follicular B Cell Pools
Jianxun Feng, Hongsheng Wang, Dong-Mi Shin, Marek Masiuk, Chen-Feng Qi and Herbert C. Morse III

J Immunol February 1, 2011, 186 (3) 1458-1466; DOI: https://doi.org/10.4049/jimmunol.1001950
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P-Rex1 and Vav1 Cooperate in the Regulation of Formyl-Methionyl-Leucyl-Phenylalanine–Dependent Neutrophil Responses
Campbell D. Lawson, Sarah Donald, Karen E. Anderson, Daniel T. Patton and Heidi C. E. Welch

J Immunol February 1, 2011, 186 (3) 1467-1476; DOI: https://doi.org/10.4049/jimmunol.1002738
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Plasmacytoid Dendritic Cell Dichotomy: Identification of IFN-α Producing Cells as a Phenotypically and Functionally Distinct Subset
Pia Björck, H. Xianne Leong and Edgar G. Engleman

J Immunol February 1, 2011, 186 (3) 1477-1485; DOI: https://doi.org/10.4049/jimmunol.1000454
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TNF Receptor-1 Is Required for the Formation of Splenic Compartments during Adult, but Not Embryonic Life
Novica M. Milićević, Karola Klaperski, Klaus Nohroudi, Živana Milićević, Katja Bieber, Babett Baraniec, Maike Blessenohl, Kathrin Kalies, Carl F. Ware and Jürgen Westermann

J Immunol February 1, 2011, 186 (3) 1486-1494; DOI: https://doi.org/10.4049/jimmunol.1000740
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IL-23–Mediated Psoriasis-Like Epidermal Hyperplasia Is Dependent on IL-17A
Heather L. Rizzo, Shinji Kagami, Kevin G. Phillips, Stephen E. Kurtz, Steven L. Jacques and Andrew Blauvelt

J Immunol February 1, 2011, 186 (3) 1495-1502; DOI: https://doi.org/10.4049/jimmunol.1001001
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CpG Promotes Cross-Presentation of Dead Cell-Associated Antigens by Pre-CD8α⁺ Dendritic Cells
Christelle de Brito, Martine Tomkowiak, Raffaella Ghittoni, Christophe Caux, Yann Leverrier and Jacqueline Marvel

J Immunol February 1, 2011, 186 (3) 1503-1511; DOI: https://doi.org/10.4049/jimmunol.1001022
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Invariant NKT Cells Inhibit Autoreactive B Cells in a Contact- and CD1d-Dependent Manner
Jun-Qi Yang, Xiangshu Wen, Peter J. Kim and Ram Raj Singh

J Immunol February 1, 2011, 186 (3) 1512-1520; DOI: https://doi.org/10.4049/jimmunol.1002373
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Lung Cancer-Derived Galectin-1 Mediates Dendritic Cell Anergy through Inhibitor of DNA Binding 3/IL-10 Signaling Pathway
Po-Lin Kuo, Jen-Yu Hung, Shau-Ku Huang, Shah-Hwa Chou, Da-En Cheng, Yuh-Jyh Jong, Chih-Hsing Hung, Chih-Jen Yang, Ying-Ming Tsai, Ya-Ling Hsu and Ming-Shyan Huang

J Immunol February 1, 2011, 186 (3) 1521-1530; DOI: https://doi.org/10.4049/jimmunol.1002940
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Restricted Microbiota and Absence of Cognate TCR Antigen Leads to an Unbalanced Generation of Th17 Cells
Matthias Lochner, Marion Bérard, Shinichiro Sawa, Siona Hauer, Valérie Gaboriau-Routhiau, Tahia Diana Fernandez, Johannes Snel, Philippe Bousso, Nadine Cerf-Bensussan and Gérard Eberl

J Immunol February 1, 2011, 186 (3) 1531-1537; DOI: https://doi.org/10.4049/jimmunol.1001723
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A Human NK Cell Activation/Inhibition Threshold Allows Small Changes in the Target Cell Surface Phenotype To Dramatically Alter Susceptibility to NK Cells
Tim D. Holmes, Yasser M. El-Sherbiny, Adam Davison, Sally L. Clough, G. Eric Blair and Graham P. Cook

J Immunol February 1, 2011, 186 (3) 1538-1545; DOI: https://doi.org/10.4049/jimmunol.1000951
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Foxp3⁺ Regulatory T Cells Control Humoral Autoimmunity by Suppressing the Development of Long-Lived Plasma Cells
Eunkyeong Jang, Wang Sik Cho, Mi-La Cho, Hyun-Joo Park, Hye-Joa Oh, Sang Mee Kang, Doo-Jin Paik and Jeehee Youn

J Immunol February 1, 2011, 186 (3) 1546-1553; DOI: https://doi.org/10.4049/jimmunol.1002942
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CD22 Is a Recycling Receptor That Can Shuttle Cargo between the Cell Surface and Endosomal Compartments of B Cells
Mary K. O’Reilly, Hua Tian and James C. Paulson

J Immunol February 1, 2011, 186 (3) 1554-1563; DOI: https://doi.org/10.4049/jimmunol.1003005

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Autophagy Regulates Endoplasmic Reticulum Homeostasis and Calcium Mobilization in T Lymphocytes
Wei Jia, Heather H. Pua, Qi-Jing Li and You-Wen He

J Immunol February 1, 2011, 186 (3) 1564-1574; DOI: https://doi.org/10.4049/jimmunol.1001822

IMMUNOGENETICS

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Although Divergent in Residues of the Peptide Binding Site, Conserved Chimpanzee Patr-AL and Polymorphic Human HLA-A*02 Have Overlapping Peptide-Binding Repertoires
Michael Gleimer, Angela R. Wahl, Heather D. Hickman, Laurent Abi-Rached, Paul J. Norman, Lisbeth A. Guethlein, John A. Hammond, Monia Draghi, Erin J. Adams, Sean Juo, Roxana Jalili, Baback Gharizadeh, Mostafa Ronaghi, K. Christopher Garcia, William H. Hildebrand and Peter Parham

J Immunol February 1, 2011, 186 (3) 1575-1588; DOI: https://doi.org/10.4049/jimmunol.1002990

HOST DEFENSE

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Persistence of Gut Mucosal Innate Immune Defenses by Enteric α-Defensin Expression in the Simian Immunodeficiency Virus Model of AIDS
Melinda M. Zaragoza, Sumathi Sankaran-Walters, Don R. Canfield, Jason K. S. Hung, Enrique Martinez, André J. Ouellette and Satya Dandekar

J Immunol February 1, 2011, 186 (3) 1589-1597; DOI: https://doi.org/10.4049/jimmunol.1002021
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CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1–Mediated Inhibition
Daniel L. Barber, Katrin D. Mayer-Barber, Carl G. Feng, Arlene H. Sharpe and Alan Sher

J Immunol February 1, 2011, 186 (3) 1598-1607; DOI: https://doi.org/10.4049/jimmunol.1003304
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TLR 2 and CD14 Mediate Innate Immunity and Lung Inflammation to Staphylococcal Panton–Valentine Leukocidin In Vivo
Ana Zivkovic, Omar Sharif, Karin Stich, Bianca Doninger, Mario Biaggio, Jacques Colinge, Martin Bilban, Ildiko Mesteri, Parastoo Hazemi, Rosa Lemmens-Gruber and Sylvia Knapp

J Immunol February 1, 2011, 186 (3) 1608-1617; DOI: https://doi.org/10.4049/jimmunol.1001665
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RIG-I/MDA5/MAVS Are Required To Signal a Protective IFN Response in Rotavirus-Infected Intestinal Epithelium
Alexis H. Broquet, Yoshihiro Hirata, Christopher S. McAllister and Martin F. Kagnoff

J Immunol February 1, 2011, 186 (3) 1618-1626; DOI: https://doi.org/10.4049/jimmunol.1002862
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Mycobacterium tuberculosis Directs Immunofocusing of CD8⁺ T Cell Responses Despite Vaccination
Joshua S. Woodworth, Daniel Shin, Mattijs Volman, Cláudio Nunes-Alves, Sarah M. Fortune and Samuel M. Behar

J Immunol February 1, 2011, 186 (3) 1627-1637; DOI: https://doi.org/10.4049/jimmunol.1002911
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c-Maf–Dependent Growth of Mycobacterium tuberculosis in a CD14^hi Subpopulation of Monocyte-Derived Macrophages
Rohan Dhiman, Anuradha Bandaru, Peter F. Barnes, Sudipto Saha, Amy Tvinnereim, Ramesh C. Nayak, Padmaja Paidipally, Vijaya Lakshmi Valluri, L. Vijaya Mohan Rao and Ramakrishna Vankayalapati

J Immunol February 1, 2011, 186 (3) 1638-1645; DOI: https://doi.org/10.4049/jimmunol.1003146
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NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1
Nao Jounai, Kouji Kobiyama, Masaaki Shiina, Kazuhiro Ogata, Ken J. Ishii and Fumihiko Takeshita

J Immunol February 1, 2011, 186 (3) 1646-1655; DOI: https://doi.org/10.4049/jimmunol.1001654
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Pyk2 Is Required for Neutrophil Degranulation and Host Defense Responses to Bacterial Infection
Lynn A. Kamen, Joseph Schlessinger and Clifford A. Lowell

J Immunol February 1, 2011, 186 (3) 1656-1665; DOI: https://doi.org/10.4049/jimmunol.1002093
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Influenza A Inhibits Th17-Mediated Host Defense against Bacterial Pneumonia in Mice
Anupa Kudva, Erich V. Scheller, Keven M. Robinson, Chris R. Crowe, Sun Mi Choi, Samantha R. Slight, Shabaana A. Khader, Patricia J. Dubin, Richard I. Enelow, Jay K. Kolls and John F. Alcorn

J Immunol February 1, 2011, 186 (3) 1666-1674; DOI: https://doi.org/10.4049/jimmunol.1002194
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IL-17 Contributes to Cell-Mediated Defense against Pulmonary Yersinia pestis Infection
Jr-Shiuan Lin, Lawrence W. Kummer, Frank M. Szaba and Stephen T. Smiley

J Immunol February 1, 2011, 186 (3) 1675-1684; DOI: https://doi.org/10.4049/jimmunol.1003303
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A Novel Role for IFN-Stimulated Gene Factor 3^II in IFN-γ Signaling and Induction of Antiviral Activity in Human Cells
Angel N. Morrow, Hana Schmeisser, Takaya Tsuno and Kathryn C. Zoon

J Immunol February 1, 2011, 186 (3) 1685-1693; DOI: https://doi.org/10.4049/jimmunol.1001359
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EBV Lytic-Phase Protein BGLF5 Contributes to TLR9 Downregulation during Productive Infection
Michiel van Gent, Bryan D. Griffin, Eufemia G. Berkhoff, Daphne van Leeuwen, Ingrid G. J. Boer, Marlyse Buisson, Franca C. Hartgers, Wim P. Burmeister, Emmanuel J. Wiertz and Maaike E. Ressing

J Immunol February 1, 2011, 186 (3) 1694-1702; DOI: https://doi.org/10.4049/jimmunol.0903120
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T Cell-Intrinsic Factors Contribute to the Differential Ability of CD8⁺ T Cells To Rapidly Secrete IFN-γ in the Absence of Antigen
Elsa N. Bou Ghanem, Christina C. Nelson and Sarah E. F. D’Orazio

J Immunol February 1, 2011, 186 (3) 1703-1712; DOI: https://doi.org/10.4049/jimmunol.1001960
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Functional Consequences of Natural Sequence Variation of Murine Cytomegalovirus m157 for Ly49 Receptor Specificity and NK Cell Activation
Alexandra J. Corbett, Jerome D. Coudert, Catherine A. Forbes and Anthony A. Scalzo

J Immunol February 1, 2011, 186 (3) 1713-1722; DOI: https://doi.org/10.4049/jimmunol.1003308

INFLAMMATION

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Mechanistic Role of MicroRNA-146a in Endotoxin-Induced Differential Cross-Regulation of TLR Signaling
Md A. Nahid, Minoru Satoh and Edward K. L. Chan

J Immunol February 1, 2011, 186 (3) 1723-1734; DOI: https://doi.org/10.4049/jimmunol.1002311
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Controlling Herpes Simplex Virus-Induced Ocular Inflammatory Lesions with the Lipid-Derived Mediator Resolvin E1
Naveen K. Rajasagi, Pradeep B. J. Reddy, Amol Suryawanshi, Sachin Mulik, Per Gjorstrup and Barry T. Rouse

J Immunol February 1, 2011, 186 (3) 1735-1746; DOI: https://doi.org/10.4049/jimmunol.1003456
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IL-1α Modulates Neutrophil Recruitment in Chronic Inflammation Induced by Hydrocarbon Oil
Pui Y. Lee, Yutaro Kumagai, Yuan Xu, Yi Li, Tolga Barker, Chao Liu, Eric S. Sobel, Osamu Takeuchi, Shizuo Akira, Minoru Satoh and Westley H. Reeves

J Immunol February 1, 2011, 186 (3) 1747-1754; DOI: https://doi.org/10.4049/jimmunol.1001328
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CR2⁺ Marginal Zone B Cell Production of Pathogenic Natural Antibodies Is C3 Independent
Keith M. Woods, Michael R. Pope, Sara M. Hoffman and Sherry D. Fleming

J Immunol February 1, 2011, 186 (3) 1755-1762; DOI: https://doi.org/10.4049/jimmunol.1002059
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Identification of Endothelial Cell Junctional Proteins and Lymphocyte Receptors Involved in Transendothelial Migration of Human Effector Memory CD4⁺ T Cells
Thomas D. Manes and Jordan S. Pober

J Immunol February 1, 2011, 186 (3) 1763-1768; DOI: https://doi.org/10.4049/jimmunol.1002835
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A Virus-Like Particle-Based Anti-Nerve Growth Factor Vaccine Reduces Inflammatory Hyperalgesia: Potential Long-Term Therapy for Chronic Pain
Till A. Röhn, William T. Ralvenius, Jolly Paul, Petra Borter, Marcela Hernandez, Robert Witschi, Paula Grest, Hanns Ulrich Zeilhofer, Martin F. Bachmann and Gary T. Jennings

J Immunol February 1, 2011, 186 (3) 1769-1780; DOI: https://doi.org/10.4049/jimmunol.1000030
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Tumor-Associated a2 Vacuolar ATPase Acts As a Key Mediator of Cancer-Related Inflammation by Inducing Pro-Tumorigenic Properties in Monocytes
Christina Kwong, Alice Gilman-Sachs and Kenneth Beaman

J Immunol February 1, 2011, 186 (3) 1781-1789; DOI: https://doi.org/10.4049/jimmunol.1002998
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IFN-γ Attenuates Hypoxia-Inducible Factor (HIF) Activity in Intestinal Epithelial Cells through Transcriptional Repression of HIF-1β
Louise E. Glover, Karina Irizarry, Melanie Scully, Eric L. Campbell, Brittelle E. Bowers, Carol M. Aherne, Douglas J. Kominsky, Christopher F. MacManus and Sean P. Colgan

J Immunol February 1, 2011, 186 (3) 1790-1798; DOI: https://doi.org/10.4049/jimmunol.1001442
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Spontaneous Pregnancy Loss Mediated by Abnormal Maternal Inflammation in Rats Is Linked to Deficient Uteroplacental Perfusion
Stephen J. Renaud, Tiziana Cotechini, Jill S. Quirt, Shannyn K. Macdonald-Goodfellow, Maha Othman and Charles H. Graham

J Immunol February 1, 2011, 186 (3) 1799-1808; DOI: https://doi.org/10.4049/jimmunol.1002679
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Senescent CD14⁺CD16⁺ Monocytes Exhibit Proinflammatory and Proatherosclerotic Activity
Ana Merino, Paula Buendia, Alejandro Martin-Malo, Pedro Aljama, Rafael Ramirez and Julia Carracedo

J Immunol February 1, 2011, 186 (3) 1809-1815; DOI: https://doi.org/10.4049/jimmunol.1001866
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Endothelial ICAM-1 Protein Induction Is Regulated by Cytosolic Phospholipase A₂α via Both NF-κB and CREB Transcription Factors
Nurit Hadad, Liron Tuval, Vered Elgazar-Carmom, Ron Levy and Rachel Levy

J Immunol February 1, 2011, 186 (3) 1816-1827; DOI: https://doi.org/10.4049/jimmunol.1000193

CLINICAL IMMUNOLOGY

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Provision of Continuous Maturation Signaling to Dendritic Cells by RIG-I–Stimulating Cytosolic RNA Synthesis of Sendai Virus
Shinji Okano, Yoshikazu Yonemitsu, Ken Shirabe, Yoshihiro Kakeji, Yoshihiko Maehara, Mamoru Harada, Yasunobu Yoshikai, Makoto Inoue, Mamoru Hasegawa and Katsuo Sueishi

J Immunol February 1, 2011, 186 (3) 1828-1839; DOI: https://doi.org/10.4049/jimmunol.0901641
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Daratumumab, a Novel Therapeutic Human CD38 Monoclonal Antibody, Induces Killing of Multiple Myeloma and Other Hematological Tumors
Michel de Weers, Yu-Tzu Tai, Michael S. van der Veer, Joost M. Bakker, Tom Vink, Daniëlle C. H. Jacobs, Lukas A. Oomen, Matthias Peipp, Thomas Valerius, Jerry W. Slootstra, Tuna Mutis, Wim K. Bleeker, Kenneth C. Anderson, Henk M. Lokhorst, Jan G. J. van de Winkel and Paul W. H. I. Parren

J Immunol February 1, 2011, 186 (3) 1840-1848; DOI: https://doi.org/10.4049/jimmunol.1003032
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In Situ B Cell-Mediated Immune Responses and Tubulointerstitial Inflammation in Human Lupus Nephritis
Anthony Chang, Scott G. Henderson, Daniel Brandt, Ni Liu, Riteesha Guttikonda, Christine Hsieh, Natasha Kaverina, Tammy O. Utset, Shane M. Meehan, Richard J. Quigg, Eric Meffre and Marcus R. Clark

J Immunol February 1, 2011, 186 (3) 1849-1860; DOI: https://doi.org/10.4049/jimmunol.1001983
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Gene Expression Patterns of Th2 Inflammation and Intercellular Communication in Asthmatic Airways
David F. Choy, Barmak Modrek, Alexander R. Abbas, Sarah Kummerfeld, Hilary F. Clark, Lawren C. Wu, Grazyna Fedorowicz, Zora Modrusan, John V. Fahy, Prescott G. Woodruff and Joseph R. Arron

J Immunol February 1, 2011, 186 (3) 1861-1869; DOI: https://doi.org/10.4049/jimmunol.1002568
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IL-1β Is Overexpressed and Aberrantly Regulated in Corticosteroid Nonresponders with Autoimmune Inner Ear Disease
Shresh Pathak, Elliot Goldofsky, Esther X. Vivas, Vincent R. Bonagura and Andrea Vambutas

J Immunol February 1, 2011, 186 (3) 1870-1879; DOI: https://doi.org/10.4049/jimmunol.1002275

CORRECTIONS

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Correction: An Inflammasome-Independent Role for Epithelial-Expressed Nlrp3 in Renal Ischemia-Reperfusion Injury
Alana A. Shigeoka, James L. Mueller, Amanpreet Kambo, John C. Mathison, Andrew J. King, Wesley F. Hall, Jean da Silva Correia, Richard J. Ulevitch, Hal M. Hoffman and Dianne B. McKay

J Immunol February 1, 2011, 186 (3) 1880; DOI: https://doi.org/10.4049/jimmunol.1090136

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IN THIS ISSUE

LETTERS TO THE EDITOR

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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