On the cover: Human monocyte-derived macrophages were infected with HIV and fixed for immunofluorescence 3 d postinfection. Colors: HIV-1 p24 Ag (green), phalloidin (red, staining F-actin), and Hoechst 33342 (blue, nuclear staining). Original magnification ×200. Lan, X., J. Xu, T. Kiyota, H. Peng, J. C. Zheng, and T. Ikezu. 2011. HIV-1 reduces Aβ-degrading enzymatic activities in primary human mononuclear phagocytes. J. Immunol. 186: 6925–6932.