On the cover: Confocal image of a human U251 glioma cell stained with wheat germ agglutinin (green) and her2/neu (red); yellow staining indicates colocalization. The complex surface reveals microvilli, microridges, and filopodia. This topography suggests a novel way that glioma cells can invade surrounding tissue, while resisting the actions of various killer lymphocytes. Hoa, N., L. Ge, Y. Kuznetsov, A. McPherson, A. N. Cornforth, J. T. H. Pham, M. P. Myers, N. Ahmed, V. S. Salsman, L. S. Lamb, Jr., J. E. Bowersock , Y. Hu, Y.-H. Zhou, and M. R. Jadus. 2010. Glioma cells display complex cell surface topographies that resist the actions of cytolytic effector lymphocytes. J. Immunol. 185: 4793–4803.