On the cover: Odorant binding protein 1a is an important autoantigen in autoimmune dacryoadenitis. Spontaneous autoimmunity in Aire-deficient mice targets a number of different organs, including the lacrimal glands. Transfer of T lymphocytes from Aire-deficient mice stimulated with odorant binding protein 1a fusion protein results in lacrimal gland autoimmunity, as demonstrated by a massive lymphocytic infiltration into the lacrimal glands and destruction of normal tissue architecture (shown). DeVoss, J. J., N. LeClair, Y. Hou, N. Grewal, K. Johannes, W. Lu, T. Yang, C. Meagher, L. Fong, E. C. Strauss, and M. S. Anderson. 2010. An autoimmune response to odorant binding protein 1a is associated with dry eye in the Aire-deficient mouse. J. Immunol. 184: 4236–4246.