The Journal of Immunology: 184 (2)

January 15, 2010; Volume 184,Issue 2

IN THIS ISSUE

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IN THIS ISSUE
J Immunol January 15, 2010, 184 (2) 533-534; DOI: https://doi.org/10.4049/jimmunol.0990111

CUTTING EDGE

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Cutting Edge: Lymphatic Vessels, Not Blood Vessels, Primarily Mediate Immune Rejections After Transplantation
Tina Dietrich, Felix Bock, Don Yuen, Deniz Hos, Björn O. Bachmann, Grit Zahn, Stanley Wiegand, Lu Chen and Claus Cursiefen

J Immunol January 15, 2010, 184 (2) 535-539; DOI: https://doi.org/10.4049/jimmunol.0903180
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Cutting Edge: Sympathetic Nervous System Increases Proinflammatory Cytokines and Exacerbates Influenza A Virus Pathogenesis
Kristie M. Grebe, Kazuyo Takeda, Heather D. Hickman, Adam M. Bailey, Alan C. Embry, Jack R. Bennink and Jonathan W. Yewdell

J Immunol January 15, 2010, 184 (2) 540-544; DOI: https://doi.org/10.4049/jimmunol.0903395
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Cutting Edge: Vascular Endothelial Growth Factor-Mediated Signaling in Human CD45RO⁺ CD4⁺ T Cells Promotes Akt and ERK Activation and Costimulates IFN-γ Production
Aninda Basu, Andre Hoerning, Dipak Datta, Monika Edelbauer, Maria P. Stack, Katiana Calzadilla, Soumitro Pal and David M. Briscoe

J Immunol January 15, 2010, 184 (2) 545-549; DOI: https://doi.org/10.4049/jimmunol.0900397
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Cutting Edge: Plasmacytoid Dendritic Cells Induce IL-10 Production in T Cells via the Delta-Like-4/Notch Axis
Nadine Kassner, Manuela Krueger, Hideo Yagita, Andrzej Dzionek, Andreas Hutloff, Richard Kroczek, Alexander Scheffold and Sascha Rutz

J Immunol January 15, 2010, 184 (2) 550-554; DOI: https://doi.org/10.4049/jimmunol.0903152

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Stored Fas Ligand, a Mediator of Rapid CTL-Mediated Killing, Has a Lower Threshold for Response Than Degranulation or Newly Synthesized Fas Ligand
Jin-Shu He, Dong-Er Gong and Hanne L. Ostergaard

J Immunol January 15, 2010, 184 (2) 555-563; DOI: https://doi.org/10.4049/jimmunol.0902465
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Glycogen Synthase Kinase 3β Activation Is a Prerequisite Signal for Cytokine Production and Chemotaxis in Human Mast Cells
Madeleine Rådinger, Hye Sun Kuehn, Mi-Sun Kim, Dean D. Metcalfe and Alasdair M. Gilfillan

J Immunol January 15, 2010, 184 (2) 564-572; DOI: https://doi.org/10.4049/jimmunol.0902931
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Peptide-MHC Class II Complex Stability Governs CD4 T Cell Clonal Selection
Christina K. Baumgartner, Andrea Ferrante, Mika Nagaoka, Jack Gorski and Laurent P. Malherbe

J Immunol January 15, 2010, 184 (2) 573-581; DOI: https://doi.org/10.4049/jimmunol.0902107
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Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1α in Long-Lived Mclk1^+/− Mouse Mutants
Dantong Wang, Danielle Malo and Siegfried Hekimi

J Immunol January 15, 2010, 184 (2) 582-590; DOI: https://doi.org/10.4049/jimmunol.0902352
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Independent Regulation of Chemokine Responsiveness and Cytolytic Function versus CD8⁺ T Cell Expansion by Dendritic Cells
Payal B. Watchmaker, Erik Berk, Ravikumar Muthuswamy, Robbie B. Mailliard, Julie A. Urban, John M. Kirkwood and Pawel Kalinski

J Immunol January 15, 2010, 184 (2) 591-597; DOI: https://doi.org/10.4049/jimmunol.0902062
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Targeting Antigen to Diverse APCs Inactivates Memory CD8⁺ T Cells without Eliciting Tissue-Destructive Effector Function
Tony J. Kenna, Tanya Waldie, Alice McNally, Meagan Thomson, Hideo Yagita, Ranjeny Thomas and Raymond J. Steptoe

J Immunol January 15, 2010, 184 (2) 598-606; DOI: https://doi.org/10.4049/jimmunol.0900032
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Antigen Specificity Determines the Pro- or Antitumoral Nature of CD8⁺ T Cells
Simone Cuff, Garry Dolton, R. James Matthews and Awen Gallimore

J Immunol January 15, 2010, 184 (2) 607-614; DOI: https://doi.org/10.4049/jimmunol.0804089
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Differential Regulation of IL-4Rα Expression by Antigen versus Cytokine Stimulation Characterizes Th2 Progression In Vivo
Georgia Perona-Wright, Katja Mohrs, Katrin D. Mayer and Markus Mohrs

J Immunol January 15, 2010, 184 (2) 615-623; DOI: https://doi.org/10.4049/jimmunol.0902408
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Mammalian Target of Rapamycin Inhibition and Alloantigen-Specific Regulatory T Cells Synergize To Promote Long-Term Graft Survival in Immunocompetent Recipients
Giorgio Raimondi, Tina L. Sumpter, Benjamin M. Matta, Mahesh Pillai, Natasha Corbitt, Yoram Vodovotz, Zhiliang Wang and Angus W. Thomson

J Immunol January 15, 2010, 184 (2) 624-636; DOI: https://doi.org/10.4049/jimmunol.0900936
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Cytohesin-1 Regulates the Arf6-Phospholipase D Signaling Axis in Human Neutrophils: Impact on Superoxide Anion Production and Secretion
Mohammed-Amine El Azreq, Valérie Garceau, Danielle Harbour, Christophe Pivot-Pajot and Sylvain G. Bourgoin

J Immunol January 15, 2010, 184 (2) 637-649; DOI: https://doi.org/10.4049/jimmunol.0901654
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Peptide-Specific, TCR-α–Driven, Coreceptor-Independent Negative Selection in TCR α-Chain Transgenic Mice
Anna L. Furmanski, Istvan Bartok, Jian-Guo Chai, Yogesh Singh, Cristina Ferreira, Diane Scott, Stephen J. Holland, Christophe Bourdeaux, Tessa Crompton and Julian Dyson

J Immunol January 15, 2010, 184 (2) 650-657; DOI: https://doi.org/10.4049/jimmunol.0902291
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Ins2 Deficiency Augments Spontaneous HLA-A*0201–Restricted T Cell Responses to Insulin
Irene Jarchum and Teresa P. DiLorenzo

J Immunol January 15, 2010, 184 (2) 658-665; DOI: https://doi.org/10.4049/jimmunol.0903414
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RasGRP1 Regulates Antigen-Induced Developmental Programming by Naive CD8 T Cells
John J. Priatel, Xiaoxi Chen, Yu-Hsuan Huang, Michael T. Chow, Lauren A. Zenewicz, Jason J. Coughlin, Hao Shen, James C. Stone, Rusung Tan and Hung Sia Teh

J Immunol January 15, 2010, 184 (2) 666-676; DOI: https://doi.org/10.4049/jimmunol.0803521
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Prostaglandin E₂ Inhibits IFN-α Secretion and Th1 Costimulation by Human Plasmacytoid Dendritic Cells via E-Prostanoid 2 and E-Prostanoid 4 Receptor Engagement
Dorit Fabricius, Marina Neubauer, Birgit Mandel, Catharina Schütz, Andreas Viardot, Angelika Vollmer, Bernd Jahrsdörfer and Klaus-Michael Debatin

J Immunol January 15, 2010, 184 (2) 677-684; DOI: https://doi.org/10.4049/jimmunol.0902028
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RNA Interference Screen in Primary Human T Cells Reveals FLT3 as a Modulator of IL-10 Levels
Anne L. Astier, Gaëlle Beriou, Thomas M. Eisenhaure, Stephen M. Anderton, David A. Hafler and Nir Hacohen

J Immunol January 15, 2010, 184 (2) 685-693; DOI: https://doi.org/10.4049/jimmunol.0902443
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Presenilin/γ-Secretase Cleaves CD46 in Response to Neisseria Infection
Nathan J. Weyand, Christine M. Calton, Dustin L. Higashi, Kristen J. Kanack and Magdalene So

J Immunol January 15, 2010, 184 (2) 694-701; DOI: https://doi.org/10.4049/jimmunol.0900522
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Gene Expression Analysis of Macrophages That Facilitate Tumor Invasion Supports a Role for Wnt-Signaling in Mediating Their Activity in Primary Mammary Tumors
Laureen S. Ojalvo, Charles A. Whittaker, John S. Condeelis and Jeffrey W. Pollard

J Immunol January 15, 2010, 184 (2) 702-712; DOI: https://doi.org/10.4049/jimmunol.0902360
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Pronounced Phenotype in Activated Regulatory T Cells during a Chronic Helminth Infection
Laura E. Layland, Jörg Mages, Christoph Loddenkemper, Achim Hoerauf, Hermann Wagner, Roland Lang and Clarissa U. Prazeres da Costa

J Immunol January 15, 2010, 184 (2) 713-724; DOI: https://doi.org/10.4049/jimmunol.0901435
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Antigen Aggregation Decides the Fate of the Allergic Immune Response
Nadja Zaborsky, Marietta Brunner, Michael Wallner, Martin Himly, Tanja Karl, Robert Schwarzenbacher, Fatima Ferreira and Gernot Achatz

J Immunol January 15, 2010, 184 (2) 725-735; DOI: https://doi.org/10.4049/jimmunol.0902080
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Nucleotide Oligomerization Binding Domain-Like Receptor Signaling Enhances Dendritic Cell-Mediated Cross-Priming In Vivo
Jumpei Asano, Hiroyuki Tada, Nobuyuki Onai, Taku Sato, Yasuo Horie, Yukari Fujimoto, Koichi Fukase, Akira Suzuki, Tak W. Mak and Toshiaki Ohteki

J Immunol January 15, 2010, 184 (2) 736-745; DOI: https://doi.org/10.4049/jimmunol.0900726
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Neuroprotective Activities of CEP-1347 in Models of NeuroAIDS
Dawn Eggert, Prasanta K. Dash, Santhi Gorantla, Huanyu Dou, Giovanni Schifitto, Sanjay B. Maggirwar, Stephen Dewhurst, Larisa Poluektova, Harris A. Gelbard and Howard E. Gendelman

J Immunol January 15, 2010, 184 (2) 746-756; DOI: https://doi.org/10.4049/jimmunol.0902962
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CTLA4Ig Alters the Course of Autoimmune Disease Development in Lyn^−/− Mice
Sarah A. Oracki, Evelyn Tsantikos, Cathy Quilici, Amanda Light, Thomas Schmidt, Andrew M. Lew, Joanne E. Martin, Ken G. Smith, Margaret L. Hibbs and David M. Tarlinton

J Immunol January 15, 2010, 184 (2) 757-763; DOI: https://doi.org/10.4049/jimmunol.0804349
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STAT3 Signaling in CD4⁺ T Cells Is Critical for the Pathogenesis of Chronic Sclerodermatous Graft-Versus-Host Disease in a Murine Model
Vedran Radojcic, Maria A. Pletneva, Hung-Rong Yen, Sanja Ivcevic, Angela Panoskaltsis-Mortari, Anita C. Gilliam, Charles G. Drake, Bruce R. Blazar and Leo Luznik

J Immunol January 15, 2010, 184 (2) 764-774; DOI: https://doi.org/10.4049/jimmunol.0903006
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Development of Murine Lupus Involves the Combined Genetic Contribution of the SLAM and FcγR Intervals within the Nba2 Autoimmune Susceptibility Locus
Trine N. Jørgensen, Jennifer Alfaro, Hilda L. Enriquez, Chao Jiang, William M. Loo, Stephanie Atencio, Melanie R. Gubbels Bupp, Christina M. Mailloux, Troy Metzger, Shannon Flannery, Stephen J. Rozzo, Brian L. Kotzin, Mario Rosemblatt, María Rosa Bono and Loren D. Erickson

J Immunol January 15, 2010, 184 (2) 775-786; DOI: https://doi.org/10.4049/jimmunol.0901322
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CD137 Promotes Proliferation and Survival of Human B Cells
Xiaoyu Zhang, Caroline J. Voskens, Michelle Sallin, Amudhan Maniar, Carolina L. Montes, Yue Zhang, Wei Lin, Guoyan Li, Erin Burch, Ming Tan, Ronna Hertzano, Andrei I. Chapoval, Koji Tamada, Brian R. Gastman, Dan H. Schulze and Scott E. Strome

J Immunol January 15, 2010, 184 (2) 787-795; DOI: https://doi.org/10.4049/jimmunol.0901619
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IFN Regulatory Factor 5 Is Required for Disease Development in the FcγRIIB^−/−Yaa and FcγRIIB^−/− Mouse Models of Systemic Lupus Erythematosus
Christophe Richez, Kei Yasuda, Ramon G. Bonegio, Amanda A. Watkins, Tamar Aprahamian, Patricia Busto, Rocco J. Richards, Chih Long Liu, Regina Cheung, Paul J. Utz, Ann Marshak-Rothstein and Ian R. Rifkin

J Immunol January 15, 2010, 184 (2) 796-806; DOI: https://doi.org/10.4049/jimmunol.0901748
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PDCA Expression by B Lymphocytes Reveals Important Functional Attributes
Dass S. Vinay, Chang H. Kim, Kyung H. Chang and Byoung S. Kwon

J Immunol January 15, 2010, 184 (2) 807-815; DOI: https://doi.org/10.4049/jimmunol.0902528
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Neurons Preferentially Respond to Self-MHC Class I Allele Products Regardless of Peptide Presented
Nathalie Escande-Beillard, Lorraine Washburn, Dan Zekzer, Zhongqi-Phyllis Wu, Shoshy Eitan, Sonja Ivkovic, Yuxin Lu, Hoa Dang, Blake Middleton, Tina V. Bilousova, Yoshitaka Yoshimura, Christopher J. Evans, Sebastian Joyce, Jide Tian and Daniel L. Kaufman

J Immunol January 15, 2010, 184 (2) 816-823; DOI: https://doi.org/10.4049/jimmunol.0902159
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Hypochlorous Acid: A Natural Adjuvant That Facilitates Antigen Processing, Cross-Priming, and the Induction of Adaptive Immunity
Zofia M. Prokopowicz, Frederick Arce, Rafal Biedron, Cheryl L.-L. Chiang, Marta Ciszek, David R. Katz, Maria Nowakowska, Szczepan Zapotoczny, Janusz Marcinkiewicz and Benjamin M. Chain

J Immunol January 15, 2010, 184 (2) 824-835; DOI: https://doi.org/10.4049/jimmunol.0902606

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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The Anti-Inflammatory and Proresolving Mediator Resolvin E1 Protects Mice from Bacterial Pneumonia and Acute Lung Injury
Hiroyuki Seki, Koichi Fukunaga, Makoto Arita, Hiroyuki Arai, Hiroki Nakanishi, Ryo Taguchi, Taku Miyasho, Rina Takamiya, Koichiro Asano, Akitoshi Ishizaka, Junzo Takeda and Bruce D. Levy

J Immunol January 15, 2010, 184 (2) 836-843; DOI: https://doi.org/10.4049/jimmunol.0901809
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The Strength of B Cell Interaction with Antigen Determines the Degree of IgM Polymerization
Jianmin Ye, Erin S. Bromage and Stephen L. Kaattari

J Immunol January 15, 2010, 184 (2) 844-850; DOI: https://doi.org/10.4049/jimmunol.0902364
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Terminal Deoxynucleotidyl Transferase Is Required for an Optimal Response to the Polysaccharide α-1,3 Dextran
Tamer I. Mahmoud and John F. Kearney

J Immunol January 15, 2010, 184 (2) 851-858; DOI: https://doi.org/10.4049/jimmunol.0902791

IMMUNOGENETICS

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An NZW-Derived Interval on Chromosome 7 Moderates Sialadenitis, But Not Insulitis in Congenic Nonobese Diabetic Mice
Rachel A. Burt, Laura Watkins, Iris K. L. Tan, Nancy Wang, Fiona Quirk, Leanne Mackin, Phillip Morgan, Jian-Guo Zhang, Stuart P. Berzins, Grant Morahan and Thomas C. Brodnicki

J Immunol January 15, 2010, 184 (2) 859-868; DOI: https://doi.org/10.4049/jimmunol.0903149

HOST DEFENSE

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Naturally Occurring Altered Peptide Ligands Control Salmonella-Specific CD4⁺ T Cell Proliferation, IFN-γ Production, and Protective Potency
Tanner M. Johanns, James M. Ertelt, Joseph C. Lai, Jared H. Rowe, Ross A. Avant and Sing Sing Way

J Immunol January 15, 2010, 184 (2) 869-876; DOI: https://doi.org/10.4049/jimmunol.0901804
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Mice with a Selective Impairment of IFN-γ Signaling in Macrophage Lineage Cells Demonstrate the Critical Role of IFN-γ–Activated Macrophages for the Control of Protozoan Parasitic Infections In Vivo
Jennifer E. Lykens, Catherine E. Terrell, Erin E. Zoller, Senad Divanovic, Aurelien Trompette, Christopher L. Karp, Julio Aliberti, Matthew J. Flick and Michael B. Jordan

J Immunol January 15, 2010, 184 (2) 877-885; DOI: https://doi.org/10.4049/jimmunol.0902346
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Regulatory B Cells Shape the Development of Th2 Immune Responses in BALB/c Mice Infected with Leishmania major Through IL-10 Production
Catherine Ronet, Yazmin Hauyon-La Torre, Mélanie Revaz-Breton, Béatris Mastelic, Fabienne Tacchini-Cottier, Jacques Louis and Pascal Launois

J Immunol January 15, 2010, 184 (2) 886-894; DOI: https://doi.org/10.4049/jimmunol.0901114
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Ectopic Activation of Mycobacterium tuberculosis-Specific CD4⁺ T Cells in Lungs of CCR7⁻^/⁻ Mice
Sofia Olmos, Sabriya Stukes and Joel D. Ernst

J Immunol January 15, 2010, 184 (2) 895-901; DOI: https://doi.org/10.4049/jimmunol.0901230
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DNAM-1/CD155 Interactions Promote Cytokine and NK Cell-Mediated Suppression of Poorly Immunogenic Melanoma Metastases
Christopher J. Chan, Daniel M. Andrews, Nicole M. McLaughlin, Hideo Yagita, Susan Gilfillan, Marco Colonna and Mark J. Smyth

J Immunol January 15, 2010, 184 (2) 902-911; DOI: https://doi.org/10.4049/jimmunol.0903225
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Factor H and Factor H-Related Protein 1 Bind to Human Neutrophils via Complement Receptor 3, Mediate Attachment to Candida albicans, and Enhance Neutrophil Antimicrobial Activity
Josephine Losse, Peter F. Zipfel and Mihály Józsi

J Immunol January 15, 2010, 184 (2) 912-921; DOI: https://doi.org/10.4049/jimmunol.0901702
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Listeria monocytogenes-Infected Human Peripheral Blood Mononuclear Cells Produce IL-1β, Depending on Listeriolysin O and NLRP3
Karolin Meixenberger, Florence Pache, Julia Eitel, Bernd Schmeck, Stefan Hippenstiel, Hortense Slevogt, Philippe N’Guessan, Martin Witzenrath, Mihai G. Netea, Trinad Chakraborty, Norbert Suttorp and Bastian Opitz

J Immunol January 15, 2010, 184 (2) 922-930; DOI: https://doi.org/10.4049/jimmunol.0901346
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Granzyme A- and B-Cluster Deficiency Delays Acute Lung Injury in Pneumovirus-Infected Mice
Reinout A. Bem, Job B. M. van Woensel, Rene Lutter, Joseph B. Domachowske, Jan Paul Medema, Helene F. Rosenberg and Albert P. Bos

J Immunol January 15, 2010, 184 (2) 931-938; DOI: https://doi.org/10.4049/jimmunol.0903029
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Immunostimulatory RNA Blocks Suppression by Regulatory T Cells
David Anz, Viktor H. Koelzer, Stefan Moder, Raffael Thaler, Tobias Schwerd, Katharina Lahl, Tim Sparwasser, Robert Besch, Hendrik Poeck, Veit Hornung, Gunther Hartmann, Simon Rothenfusser, Carole Bourquin and Stefan Endres

J Immunol January 15, 2010, 184 (2) 939-946; DOI: https://doi.org/10.4049/jimmunol.0901245
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IFN-γ–Dependent Activation of Macrophages during Experimental Infections by Mycobacterium ulcerans Is Impaired by the Toxin Mycolactone
Egídio Torrado, Alexandra G. Fraga, Elsa Logarinho, Teresa G. Martins, Jenny A. Carmona, José B. Gama, Maria A. Carvalho, Fernanda Proença, Antonio G. Castro and Jorge Pedrosa

J Immunol January 15, 2010, 184 (2) 947-955; DOI: https://doi.org/10.4049/jimmunol.0902717
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Subversion of Innate Immune Responses by Brucella through the Targeted Degradation of the TLR Signaling Adapter, MAL
Dola Sengupta, Alicia Koblansky, Jennifer Gaines, Tim Brown, A. Phillip West, Dekai Zhang, Tak Nishikawa, Sung-Gyoo Park, R. Martin Roop II and Sankar Ghosh

J Immunol January 15, 2010, 184 (2) 956-964; DOI: https://doi.org/10.4049/jimmunol.0902008
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Vitamin D Decreases Respiratory Syncytial Virus Induction of NF-κB–Linked Chemokines and Cytokines in Airway Epithelium While Maintaining the Antiviral State
Sif Hansdottir, Martha M. Monick, Nina Lovan, Linda Powers, Alicia Gerke and Gary W. Hunninghake

J Immunol January 15, 2010, 184 (2) 965-974; DOI: https://doi.org/10.4049/jimmunol.0902840
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Surfactant Protein B Propeptide Contains a Saposin-Like Protein Domain with Antimicrobial Activity at Low pH
Li Yang, Jan Johansson, Ross Ridsdale, Hanna Willander, Michael Fitzen, Henry T. Akinbi and Timothy E. Weaver

J Immunol January 15, 2010, 184 (2) 975-983; DOI: https://doi.org/10.4049/jimmunol.0900650
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AIDS Progression Is Associated with the Emergence of IL-17–Producing Cells Early After Simian Immunodeficiency Virus Infection
Laure Campillo-Gimenez, Marie-Christine Cumont, Michèle Fay, Hassen Kared, Valérie Monceaux, Ousmane Diop, Michaela Müller-Trutwin, Bruno Hurtrel, Yves Lévy, John Zaunders, Michel Dy, Maria C. Leite-de-Moraes, Carole Elbim and Jérôme Estaquier

J Immunol January 15, 2010, 184 (2) 984-992; DOI: https://doi.org/10.4049/jimmunol.0902316

INFLAMMATION

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Crucial Role of Phospholipase Cε in Induction of Local Skin Inflammatory Reactions in the Elicitation Stage of Allergic Contact Hypersensitivity
Lizhi Hu, Hironori Edamatsu, Nobuyuki Takenaka, Shuzo Ikuta and Tohru Kataoka

J Immunol January 15, 2010, 184 (2) 993-1002; DOI: https://doi.org/10.4049/jimmunol.0901816
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Inhibition of Th2 Adaptive Immune Responses and Pulmonary Inflammation by Leukocyte Ig-Like Receptor B4 on Dendritic Cells
Rebecca G. Breslow, Jayanti J. Rao, Wei Xing, David I. Hong, Nora A. Barrett and Howard R. Katz

J Immunol January 15, 2010, 184 (2) 1003-1013; DOI: https://doi.org/10.4049/jimmunol.0900877
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Fos Proteins Suppress Dextran Sulfate Sodium-Induced Colitis through Inhibition of NF-κB
Yasunari Takada, Neelanjan Ray, Eiji Ikeda, Tomohiro Kawaguchi, Masayoshi Kuwahara, Erwin F. Wagner and Koichi Matsuo

J Immunol January 15, 2010, 184 (2) 1014-1021; DOI: https://doi.org/10.4049/jimmunol.0901196
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Peroxiredoxin 1 Stimulates Secretion of Proinflammatory Cytokines by Binding to TLR4
Jonah R. Riddell, Xiang-Yang Wang, Hans Minderman and Sandra O. Gollnick

J Immunol January 15, 2010, 184 (2) 1022-1030; DOI: https://doi.org/10.4049/jimmunol.0901945
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CD8 T Cell-Initiated Vascular Endothelial Growth Factor Expression Promotes Central Nervous System Vascular Permeability under Neuroinflammatory Conditions
Georgette L. Suidan, Jonathan W. Dickerson, Yi Chen, Jeremiah R. McDole, Pulak Tripathi, Istvan Pirko, Kim B. Seroogy and Aaron J. Johnson

J Immunol January 15, 2010, 184 (2) 1031-1040; DOI: https://doi.org/10.4049/jimmunol.0902773
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Heat Shock Transcription Factor 1 Inhibits Expression of IL-6 through Activating Transcription Factor 3
Ryosuke Takii, Sachiye Inouye, Mitsuaki Fujimoto, Tamami Nakamura, Toyohide Shinkawa, Ramachandran Prakasam, Ke Tan, Naoki Hayashida, Hitoshi Ichikawa, Tsonwin Hai and Akira Nakai

J Immunol January 15, 2010, 184 (2) 1041-1048; DOI: https://doi.org/10.4049/jimmunol.0902579
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Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures
Emeline Van Goethem, Renaud Poincloux, Fabienne Gauffre, Isabelle Maridonneau-Parini and Véronique Le Cabec

J Immunol January 15, 2010, 184 (2) 1049-1061; DOI: https://doi.org/10.4049/jimmunol.0902223
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Mycobacterium bovis Bacillus Calmette-Guérin Killed by Extended Freeze-Drying Targets Plasmacytoid Dendritic Cells To Regulate Lung Inflammation
Micheline Lagranderie, Mohammad Abolhassani, Jeroen A. J. Vanoirbeek, Carla Lima, Anne-Marie Balazuc, B. Boris Vargaftig and Gilles Marchal

J Immunol January 15, 2010, 184 (2) 1062-1070; DOI: https://doi.org/10.4049/jimmunol.0901822
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Signaling Role for Lysophosphatidylcholine Acyltransferase 3 in Receptor-Regulated Arachidonic Acid Reacylation Reactions in Human Monocytes
Gema Pérez-Chacón, Alma M. Astudillo, Violeta Ruipérez, María A. Balboa and Jesús Balsinde

J Immunol January 15, 2010, 184 (2) 1071-1078; DOI: https://doi.org/10.4049/jimmunol.0902257

CLINICAL IMMUNOLOGY

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Increased Plasma-Immune Cytokines throughout the High-Dose Melphalan-Induced Lymphodepletion in Patients with Multiple Myeloma: A Window for Adoptive Immunotherapy
Maud Condomines, Jean-Luc Veyrune, Marion Larroque, Philippe Quittet, Pascal Latry, Cécile Lugagne, Catherine Hertogh, Tarik Kanouni, Jean-François Rossi and Bernard Klein

J Immunol January 15, 2010, 184 (2) 1079-1084; DOI: https://doi.org/10.4049/jimmunol.0804159
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Differential Responses to Smith D Autoantigen by Mice with HLA-DR and HLA-DQ Transgenes: Dominant Responses by HLA-DR3 Transgenic Mice with Diversification of Autoantibodies to Small Nuclear Ribonucleoprotein, Double-Stranded DNA, and Nuclear Antigens
Chao Jiang, Umesh S. Deshmukh, Felicia Gaskin, Harini Bagavant, Julie Hanson, Chella S. David and Shu Man Fu

J Immunol January 15, 2010, 184 (2) 1085-1091; DOI: https://doi.org/10.4049/jimmunol.0902670
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Predominant Expression of CCL2 at the Tumor Site of Prostate Cancer Patients Directs a Selective Loss of Immunological Tolerance to CCL2 That Could Be Amplified in a Beneficial Manner
Liat Izhak, Gizi Wildbaum, Weinberg Uri, Yuval Shaked, Jennifer Alami, Daniel Dumont, Avi Stein and Nathan Karin

J Immunol January 15, 2010, 184 (2) 1092-1101; DOI: https://doi.org/10.4049/jimmunol.0902725
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CD56^highCD16⁻CD62L⁻ NK Cells Accumulate in Allergic Contact Dermatitis and Contribute to the Expression of Allergic Responses
Teresa Carbone, Francesca Nasorri, Davide Pennino, Kilian Eyerich, Stefanie Foerster, Loredana Cifaldi, Claudia Traidl-Hoffman, Heidrun Behrendt and Andrea Cavani

J Immunol January 15, 2010, 184 (2) 1102-1110; DOI: https://doi.org/10.4049/jimmunol.0902518
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CD40 Ligand-Induced Carcinoma Cell Death: A Balance between Activation of TNFR-Associated Factor (TRAF) 3-Dependent Death Signals and Suppression of TRAF6-Dependent Survival Signals
Taha Elmetwali, Lawrence S. Young and Daniel H. Palmer

J Immunol January 15, 2010, 184 (2) 1111-1120; DOI: https://doi.org/10.4049/jimmunol.0900528

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J Immunol January 15, 2010, 184 (2) 1121; DOI: https://doi.org/10.4049/jimmunol.0990112

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IN THIS ISSUE

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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