On the cover: Genetic mapping of the polymorphism that determines expression level of IL2RA, the gene encoding the IL-2Rα subunit (CD25). The peak of association with IL2RA mRNA level coincides with one of the two peaks of diabetes association at IL2RA intron 1: the diabetes-predisposing allele directs lower levels of expression. Qu, H.-Q., D. J. Verlaan, B. Ge, Y. Lu, K. C. L. Lam, R. Grabs, E. Harmsen, T. J. Hudson, H. Hakonarson, T. Pastinen, and C. Polychronakos. 2009. A cis-acting regulatory variant in the IL2RA locus. J. Immunol 183: 5158–5162.