The Journal of Immunology: 182 (8)

April 15, 2009; Volume 182,Issue 8

IN THIS ISSUE

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IN THIS ISSUE

J Immunol April 15, 2009, 182 (8) 4493-4494; DOI: https://doi.org/10.4049/jimmunol.0990021

LETTERS TO THE EDITOR

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Comment on “Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching”
Hideharu Sekine, Ricardo C. Ferreira, Qiang Pan-Hammarström, Lennart Hammarström, Gary S. Gilkeson and Timothy W. Behrens

J Immunol April 15, 2009, 182 (8) 4495-4496; DOI: https://doi.org/10.4049/jimmunol.0990026
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Response to Comment on “Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching”
Jeroen E. J. Guikema, Carol E. Schrader, Stephen P. Baker, Winfried Edelmann and Janet Stavnezer

J Immunol April 15, 2009, 182 (8) 4496-4497; DOI: https://doi.org/10.4049/jimmunol.0990027
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Comment on “Experimental Extracorporeal Photopheresis Inhibits the Sensitization and Effector Phases of Contact Hypersensitivity via Two Mechanisms: Generation of IL-10 and Induction of Regulatory T Cells”
Roberta Rizzo, Marina Stignani, Loredana Melchiorri and Olavio R. Baricordi

J Immunol April 15, 2009, 182 (8) 4497; DOI: https://doi.org/10.4049/jimmunol.0990025

BRIEF REVIEWS

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Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer
Suzanne Ostrand-Rosenberg and Pratima Sinha

J Immunol April 15, 2009, 182 (8) 4499-4506; DOI: https://doi.org/10.4049/jimmunol.0802740

CUTTING EDGE

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Cutting Edge: Lung Mucosal Th17-Mediated Responses Induce Polymeric Ig Receptor Expression by the Airway Epithelium and Elevate Secretory IgA Levels
Zeina Jaffar, Maria E. Ferrini, Lou A. Herritt and Kevan Roberts

J Immunol April 15, 2009, 182 (8) 4507-4511; DOI: https://doi.org/10.4049/jimmunol.0900237
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Cutting Edge: IL-2 Immune Complexes As a Therapy for Persistent Virus Infection
Michael J. Molloy, Weijun Zhang and Edward J. Usherwood

J Immunol April 15, 2009, 182 (8) 4512-4515; DOI: https://doi.org/10.4049/jimmunol.0804175
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Cutting Edge: A Critical Role of B and T Lymphocyte Attenuator in Peripheral T Cell Tolerance Induction
Xikui Liu, Maria Alexiou, Natalia Martin-Orozco, Yeonseok Chung, Roza I. Nurieva, Li Ma, Qiang Tian, George Kollias, Sijie Lu, Daniel Graf and Chen Dong

J Immunol April 15, 2009, 182 (8) 4516-4520; DOI: https://doi.org/10.4049/jimmunol.0803161

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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IL-22-Dependent Attenuation of T Cell-Dependent (ConA) Hepatitis in Herpes Virus Entry Mediator Deficiency
Christian Wahl, Ursula Maria Wegenka, Frank Leithäuser, Reinhold Schirmbeck and Jörg Reimann

J Immunol April 15, 2009, 182 (8) 4521-4528; DOI: https://doi.org/10.4049/jimmunol.0802810
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Early Hematopoietic Zinc Finger Protein Prevents Tumor Cell Recognition by Natural Killer Cells
Rosanna La Rocca, Mariateresa Fulciniti, Tadepally Lakshmikanth, Maria Mesuraca, Talib Hassan Ali, Valerio Mazzei, Nicola Amodio, Lucio Catalano, Bruno Rotoli, Ouathek Ouerfelli, Michele Grieco, Elio Gulletta, Heather M. Bond, Giovanni Morrone, Soldano Ferrone and Ennio Carbone

J Immunol April 15, 2009, 182 (8) 4529-4537; DOI: https://doi.org/10.4049/jimmunol.0802109
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Induction of Tumor Cell Apoptosis or Necrosis by Conditional Expression of Cell Death Proteins: Analysis of Cell Death Pathways and In Vitro Immune Stimulatory Potential
Christine Lohmann, Andreas Muschaweckh, Susanne Kirschnek, Luise Jennen, Hermann Wagner and Georg Häcker

J Immunol April 15, 2009, 182 (8) 4538-4546; DOI: https://doi.org/10.4049/jimmunol.0803989
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FcγRIIA and FcγRIIIB Mediate Nuclear Factor Activation through Separate Signaling Pathways in Human Neutrophils
Erick García-García, Georgina Nieto-Castañeda, Melissa Ruiz-Saldaña, Nancy Mora and Carlos Rosales

J Immunol April 15, 2009, 182 (8) 4547-4556; DOI: https://doi.org/10.4049/jimmunol.0801468
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Costimulation of Dendritic Epidermal γδ T Cells by a New NKG2D Ligand Expressed Specifically in the Skin
Michael I. Whang, Nadia Guerra and David H. Raulet

J Immunol April 15, 2009, 182 (8) 4557-4564; DOI: https://doi.org/10.4049/jimmunol.0802439
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A Single-Chain H-2D^b Molecule Presenting an Influenza Virus Nucleoprotein Epitope Shows Enhanced Ability at Stimulating CD8⁺ T Cell Responses In Vivo
Michael J. Palmowski, Mathew Parker, Kaushik Choudhuri, Christopher Chiu, Margaret F. C. Callan, P. Anton van der Merwe, Vincenzo Cerundolo and Keith G. Gould

J Immunol April 15, 2009, 182 (8) 4565-4571; DOI: https://doi.org/10.4049/jimmunol.0803893
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NK Cell Responsiveness Is Tuned Commensurate with the Number of Inhibitory Receptors for Self-MHC Class I: The Rheostat Model
Nathalie T. Joncker, Nadine C. Fernandez, Emmanuel Treiner, Eric Vivier and David H. Raulet

J Immunol April 15, 2009, 182 (8) 4572-4580; DOI: https://doi.org/10.4049/jimmunol.0803900
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Thymic OX40 Expression Discriminates Cells Undergoing Strong Responses to Selection Ligands
Mark Klinger, Joong Kyu Kim, Stephen A. Chmura, Andrea Barczak, David J. Erle and Nigel Killeen

J Immunol April 15, 2009, 182 (8) 4581-4589; DOI: https://doi.org/10.4049/jimmunol.0900010
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Early Infection Termination Affects Number of CD8⁺ Memory T Cells and Protective Capacities in Listeria monocytogenes-Infected Mice upon Rechallenge
Kuo-En Tseng, Cheng-Yu Chung, Weng Siong H’ng and Shih-Lien Wang

J Immunol April 15, 2009, 182 (8) 4590-4600; DOI: https://doi.org/10.4049/jimmunol.0801125
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The Amino Acid Sequences Flanking an Antigenic Determinant Can Strongly Affect MHC Class I Cross-Presentation without Altering Direct Presentation
Xueying Ma, Amparo Serna, Ren-Huan Xu and Luis J. Sigal

J Immunol April 15, 2009, 182 (8) 4601-4607; DOI: https://doi.org/10.4049/jimmunol.0803806
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Rabbit Polyclonal Mouse Antithymocyte Globulin Administration Alters Dendritic Cell Profile and Function in NOD Mice to Suppress Diabetogenic Responses
Yanfei Huang, Matthew Parker, Changqing Xia, Ruihua Peng, Clive Wasserfall, Tracy Clarke, Lizhen Wu, Tayseer Chowdhry, Martha Campbell-Thompson, John Williams, Michael Clare-Salzler, Mark A. Atkinson and Karl L. Womer

J Immunol April 15, 2009, 182 (8) 4608-4615; DOI: https://doi.org/10.4049/jimmunol.0713269
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The A_2B Adenosine Receptor Impairs the Maturation and Immunogenicity of Dendritic Cells
Jeffrey M. Wilson, William G. Ross, Oma N. Agbai, Renea Frazier, Robert A. Figler, Jayson Rieger, Joel Linden and Peter B. Ernst

J Immunol April 15, 2009, 182 (8) 4616-4623; DOI: https://doi.org/10.4049/jimmunol.0801279
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Calcitriol Suppresses Antiretinal Autoimmunity through Inhibitory Effects on the Th17 Effector Response
Jun Tang, Ru Zhou, Dror Luger, Wei Zhu, Phyllis B. Silver, Rafael S. Grajewski, Shao-Bo Su, Chi-Chao Chan, Luciano Adorini and Rachel R. Caspi

J Immunol April 15, 2009, 182 (8) 4624-4632; DOI: https://doi.org/10.4049/jimmunol.0801543
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Activin A Promotes the TGF-β-Induced Conversion of CD4⁺CD25⁻ T Cells into Foxp3⁺ Induced Regulatory T Cells
Samuel Huber, Felix R. Stahl, Jörg Schrader, Stefan Lüth, Katrin Presser, Antonella Carambia, Richard A. Flavell, Sabine Werner, Manfred Blessing, Johannes Herkel and Christoph Schramm

J Immunol April 15, 2009, 182 (8) 4633-4640; DOI: https://doi.org/10.4049/jimmunol.0803143
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Selective Requirement for c-Myc at an Early Stage of Vα14i NKT Cell Development
Marcin P. Mycko, Isabel Ferrero, Anne Wilson, Wei Jiang, Teresa Bianchi, Andreas Trumpp and H. Robson MacDonald

J Immunol April 15, 2009, 182 (8) 4641-4648; DOI: https://doi.org/10.4049/jimmunol.0803394
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A Positive Feedback Loop of IL-21 Signaling Provoked by Homeostatic CD4⁺CD25⁻ T Cell Expansion Is Essential for the Development of Arthritis in Autoimmune K/BxN Mice
Eunkyeong Jang, Sin-Hye Cho, Hyunjoo Park, Doo-Jin Paik, Jung Mogg Kim and Jeehee Youn

J Immunol April 15, 2009, 182 (8) 4649-4656; DOI: https://doi.org/10.4049/jimmunol.0804350
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Langerhans Cells Are Not Required for the CD8 T Cell Response to Epidermal Self-Antigens
Laura S. Bursch, Benjamin E. Rich and Kristin A. Hogquist

J Immunol April 15, 2009, 182 (8) 4657-4664; DOI: https://doi.org/10.4049/jimmunol.0803656
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Maintenance of Peripheral Tolerance through Controlled Tissue Homing of Antigen-Specific T Cells in K14-mOVA Mice
Teresa Bianchi, Laura B. Pincus, Marc-André Wurbel, Benjamin E. Rich, Thomas S. Kupper, Robert C. Fuhlbrigge and Marianne Boes

J Immunol April 15, 2009, 182 (8) 4665-4674; DOI: https://doi.org/10.4049/jimmunol.0803628
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Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells
Derese Getnet, Charles H. Maris, Edward L. Hipkiss, Joseph F. Grosso, Timothy J. Harris, Hung-Rong Yen, Tullia C. Bruno, Satoshi Wada, Adam Adler, Robert W. Georgantas, Chunfa Jie, Monica V. Goldberg, Drew M. Pardoll and Charles G. Drake

J Immunol April 15, 2009, 182 (8) 4675-4685; DOI: https://doi.org/10.4049/jimmunol.0803400
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Inducible MHC Class II Expression by Mast Cells Supports Effector and Regulatory T Cell Activation
Taku Kambayashi, Eric J. Allenspach, John T. Chang, Tao Zou, Jonathan E. Shoag, Steven L. Reiner, Andrew J. Caton and Gary A. Koretzky

J Immunol April 15, 2009, 182 (8) 4686-4695; DOI: https://doi.org/10.4049/jimmunol.0803180
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Inositol 1,4,5-Trisphosphate 3-Kinase B Is a Negative Regulator of BCR Signaling That Controls B Cell Selection and Tolerance Induction
Andrew T. Miller, Daniel R. Beisner, Daorong Liu and Michael P. Cooke

J Immunol April 15, 2009, 182 (8) 4696-4704; DOI: https://doi.org/10.4049/jimmunol.0802850
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Nerve Growth Factor and Neurotrophin-3 Mediate Survival of Pulmonary Plasma Cells during the Allergic Airway Inflammation
Melanie Abram, Michael Wegmann, Verena Fokuhl, Sanchaita Sonar, Elke Olga Luger, Sebastian Kerzel, Andreas Radbruch, Harald Renz and Michael Zemlin

J Immunol April 15, 2009, 182 (8) 4705-4712; DOI: https://doi.org/10.4049/jimmunol.0802814
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Superantigen- and TLR-Dependent Activation of Tonsillar B Cells after Receptor-Mediated Endocytosis
Johan Jendholm, Matthias Mörgelin, Maria Laura A. Perez Vidakovics, Michael Carlsson, Hakon Leffler, Lars-Olaf Cardell and Kristian Riesbeck

J Immunol April 15, 2009, 182 (8) 4713-4720; DOI: https://doi.org/10.4049/jimmunol.0803032
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The Generation of Influenza-Specific Humoral Responses Is Impaired in ST6Gal I-Deficient Mice
Junwei Zeng, Hye Mee Joo, Bheemreddy Rajini, Jens P. Wrammert, Mark Y. Sangster and Thandi M. Onami

J Immunol April 15, 2009, 182 (8) 4721-4727; DOI: https://doi.org/10.4049/jimmunol.0802833
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Adaptive Immune Response in JAM-C-Deficient Mice: Normal Initiation but Reduced IgG Memory
Claudia Zimmerli, Boris P. L. Lee, Gaby Palmer, Cem Gabay, Ralf Adams, Michel Aurrand-Lions and Beat A. Imhof

J Immunol April 15, 2009, 182 (8) 4728-4736; DOI: https://doi.org/10.4049/jimmunol.0803892
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IL-9 Promotes IL-13-Dependent Paneth Cell Hyperplasia and Up-Regulation of Innate Immunity Mediators in Intestinal Mucosa
Valérie Steenwinckel, Jamila Louahed, Muriel M. Lemaire, Caroline Sommereyns, Guy Warnier, Andrew McKenzie, Frank Brombacher, Jacques Van Snick and Jean-Christophe Renauld

J Immunol April 15, 2009, 182 (8) 4737-4743; DOI: https://doi.org/10.4049/jimmunol.0801941
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Statins Impair CD1d-Mediated Antigen Presentation through the Inhibition of Prenylation
Masood A. Khan, Richard M. Gallo, Gourapura J. Renukaradhya, Wenjun Du, Jacquelyn Gervay-Hague and Randy R. Brutkiewicz

J Immunol April 15, 2009, 182 (8) 4744-4750; DOI: https://doi.org/10.4049/jimmunol.0804311
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Association of HIV-Specific and Total CD8⁺ T Memory Phenotypes in Subtype C HIV-1 Infection with Viral Set Point
Wendy A. Burgers, Catherine Riou, Mandla Mlotshwa, Pholo Maenetje, Debra de Assis Rosa, Jason Brenchley, Koleka Mlisana, Daniel C. Douek, Richard Koup, Mario Roederer, Guy de Bruyn, Salim Abdool Karim, Carolyn Williamson and Clive M. Gray and the CAPRISA 002 Acute Infection Study Team

J Immunol April 15, 2009, 182 (8) 4751-4761; DOI: https://doi.org/10.4049/jimmunol.0803801
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Drak2 Is Upstream of p70S6 Kinase: Its Implication in Cytokine-Induced Islet Apoptosis, Diabetes, and Islet Transplantation
Jianning Mao, Hongyu Luo, Bing Han, Richard Bertrand and Jiangping Wu

J Immunol April 15, 2009, 182 (8) 4762-4770; DOI: https://doi.org/10.4049/jimmunol.0802255
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CD30 Is Required for CCL21 Expression and CD4 T Cell Recruitment in the Absence of Lymphotoxin Signals
Vasileios Bekiaris, Fabrina Gaspal, Mi-Yeon Kim, David R. Withers, Fiona M. McConnell, Graham Anderson and Peter J. L. Lane

J Immunol April 15, 2009, 182 (8) 4771-4775; DOI: https://doi.org/10.4049/jimmunol.0803481

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Interaction of Bap31 and MHC Class I Molecules and Their Traffic Out of the Endoplasmic Reticulum
Fumiyoshi Abe, Nancy Van Prooyen, John J. Ladasky and Michael Edidin

J Immunol April 15, 2009, 182 (8) 4776-4783; DOI: https://doi.org/10.4049/jimmunol.0800242
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Natural Lipid Ligands Associated with Human CD1d Targeted to Different Subcellular Compartments
Weiming Yuan, Suk-Jo Kang, James E. Evans and Peter Cresswell

J Immunol April 15, 2009, 182 (8) 4784-4791; DOI: https://doi.org/10.4049/jimmunol.0803981
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Evolution of the Ikaros Gene Family: Implications for the Origins of Adaptive Immunity
Liza B. John, Simon Yoong and Alister C. Ward

J Immunol April 15, 2009, 182 (8) 4792-4799; DOI: https://doi.org/10.4049/jimmunol.0802372
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Brief Residence at the Plasma Membrane of the MHC Class I-Related Chain B Is Due to Clathrin-Mediated Cholesterol-Dependent Endocytosis and Shedding
Sonia Agüera-González, Philippe Boutet, Hugh T. Reyburn and Mar Valés-Gómez

J Immunol April 15, 2009, 182 (8) 4800-4808; DOI: https://doi.org/10.4049/jimmunol.0800713
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Steric Hindrance and Fast Dissociation Explain the Lack of Immunogenicity of the Minor Histocompatibility HA-1^Arg Null Allele
Eric Spierings, Stéphanie Gras, Jean-Baptiste Reiser, Bregje Mommaas, Mathilde Almekinders, Michel G. D. Kester, Anne Chouquet, Madalen Le Gorrec, Jan W. Drijfhout, Ferry Ossendorp, Dominique Housset and Els Goulmy

J Immunol April 15, 2009, 182 (8) 4809-4816; DOI: https://doi.org/10.4049/jimmunol.0803911
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Trimolecular Complex Formation of IgE, FcεRI, and a Recombinant Nonanaphylactic Single-Chain Antibody Fragment with High Affinity for IgE
Christian Lupinek, Kenneth H. Roux, Sylvia Laffer, Ingrid Rauter, Kavita Reginald, Michael Kneidinger, Katharina Blatt, Tanja Ball, Ines Pree, Beatrice Jahn-Schmid, Jean-Pierre Allam, Natalija Novak, Anja Drescher, Franz Kricek, Peter Valent, Hakan Englund and Rudolf Valenta

J Immunol April 15, 2009, 182 (8) 4817-4829; DOI: https://doi.org/10.4049/jimmunol.0800726
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N-Glycosylation Enhances Presentation of a MHC Class I-Restricted Epitope from Tyrosinase
Marina Ostankovitch, Michelle Altrich-VanLith, Valentina Robila and Victor H. Engelhard

J Immunol April 15, 2009, 182 (8) 4830-4835; DOI: https://doi.org/10.4049/jimmunol.0802902
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Thrombin Binding Predicts the Effects of Sequence Changes in a Human Monoclonal Antiphospholipid Antibody on Its In Vivo Biologic Actions
Ian Giles, Charis Pericleous, Xiaowei Liu, Jasmine Ehsanullah, Lindsey Clarke, Paul Brogan, Marvin Newton-West, Robert Swerlick, Anastasia Lambrianides, Pojen Chen, David Latchman, David Isenberg, Silvia Pierangeli and Anisur Rahman

J Immunol April 15, 2009, 182 (8) 4836-4843; DOI: https://doi.org/10.4049/jimmunol.0804241
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Critical and Multiple Roles for the CD3ε Intracytoplasmic Tail in Double Negative to Double Positive Thymocyte Differentiation
Jean-Francois Brodeur, Samantha Li, Maria da Silva Martins, Louise Larose and Vibhuti P. Dave

J Immunol April 15, 2009, 182 (8) 4844-4853; DOI: https://doi.org/10.4049/jimmunol.0803679

HOST DEFENSE

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Selective Transcriptional Down-Regulation of Human Rhinovirus-Induced Production of CXCL10 from Airway Epithelial Cells via the MEK1 Pathway
Raza S. Zaheer, Rommy Koetzler, Neil S. Holden, Shahina Wiehler and David Proud

J Immunol April 15, 2009, 182 (8) 4854-4864; DOI: https://doi.org/10.4049/jimmunol.0802401
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A Protective Role for Dengue Virus-Specific CD8⁺ T Cells
Lauren E. Yauch, Raphaël M. Zellweger, Maya F. Kotturi, Afrina Qutubuddin, John Sidney, Bjoern Peters, Tyler R. Prestwood, Alessandro Sette and Sujan Shresta

J Immunol April 15, 2009, 182 (8) 4865-4873; DOI: https://doi.org/10.4049/jimmunol.0801974
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Host-Derived Interleukin-1α Is Important in Determining the Immunogenicity of 3-Methylcholantrene Tumor Cells
Moshe Elkabets, Yakov Krelin, Shahar Dotan, Adelheid Cerwenka, Angel Porgador, Rachel G. Lichtenstein, Malka R. White, Margot Zoller, Yoichizo Iwakura, Charles A. Dinarello, Elena Voronov and Ron N. Apte

J Immunol April 15, 2009, 182 (8) 4874-4881; DOI: https://doi.org/10.4049/jimmunol.0803916
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Protective Response to Leishmania major in BALB/c Mice Requires Antigen Processing in the Absence of DM
Tirumalai Kamala and Navreet K. Nanda

J Immunol April 15, 2009, 182 (8) 4882-4890; DOI: https://doi.org/10.4049/jimmunol.0803956
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Group V Secretory Phospholipase A₂ Modulates Phagosome Maturation and Regulates the Innate Immune Response against Candida albicans
Barbara Balestrieri, Akiko Maekawa, Wei Xing, Michael H. Gelb, Howard R. Katz and Jonathan P. Arm

J Immunol April 15, 2009, 182 (8) 4891-4898; DOI: https://doi.org/10.4049/jimmunol.0803776
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Differential Requirements for Protection against Mucosal Challenge with Francisella tularensis in the Presence versus Absence of Cholera Toxin B and Inactivated F. tularensis
Constantine Bitsaktsis, Deepak B. Rawool, Ying Li, Nitin V. Kurkure, Bibiana Iglesias and Edmund J. Gosselin

J Immunol April 15, 2009, 182 (8) 4899-4909; DOI: https://doi.org/10.4049/jimmunol.0803242
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The NF-κB RelA Subunit Confers Resistance to Leishmania major by Inducing Nitric Oxide Synthase 2 and Fas Expression but Not Th1 Differentiation
Setsuko Mise-Omata, Etsushi Kuroda, Tsutomu Sugiura, Uki Yamashita, Yuichi Obata and Takahiro S. Doi

J Immunol April 15, 2009, 182 (8) 4910-4916; DOI: https://doi.org/10.4049/jimmunol.0800967
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A Novel Hybrid Yeast-Human Network Analysis Reveals an Essential Role for FNBP1L in Antibacterial Autophagy
Alan Huett, Aylwin Ng, Zhifang Cao, Petric Kuballa, Masaaki Komatsu, Mark J. Daly, Daniel K. Podolsky and Ramnik J. Xavier

J Immunol April 15, 2009, 182 (8) 4917-4930; DOI: https://doi.org/10.4049/jimmunol.0803050
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Important Role for CC Chemokine Ligand 2-Dependent Lung Mononuclear Phagocyte Recruitment to Inhibit Sepsis in Mice Infected with Streptococcus pneumoniae
Christine Winter, Wiebke Herbold, Regina Maus, Florian Länger, David E. Briles, James C. Paton, Tobias Welte and Ulrich A. Maus

J Immunol April 15, 2009, 182 (8) 4931-4937; DOI: https://doi.org/10.4049/jimmunol.0804096
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Requisite Role for the Dectin-1 β-Glucan Receptor in Pulmonary Defense against Aspergillus fumigatus
Jessica L. Werner, Allison E. Metz, Dawn Horn, Trenton R. Schoeb, Matthew M. Hewitt, Lisa M. Schwiebert, Ines Faro-Trindade, Gordon D. Brown and Chad Steele

J Immunol April 15, 2009, 182 (8) 4938-4946; DOI: https://doi.org/10.4049/jimmunol.0804250
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Lipocalin 2 Is Required for Pulmonary Host Defense against Klebsiella Infection
Yvonne R. Chan, Jessica S. Liu, Derek A. Pociask, Mingquan Zheng, Timothy A. Mietzner, Thorsten Berger, Tak W. Mak, Matthew C. Clifton, Roland K. Strong, Prabir Ray and Jay K. Kolls

J Immunol April 15, 2009, 182 (8) 4947-4956; DOI: https://doi.org/10.4049/jimmunol.0803282

INFLAMMATION

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Contribution of Adenosine A2B Receptors to Inflammatory Parameters of Experimental Colitis
Julia-Stefanie Frick, Christopher F. MacManus, Melanie Scully, Louise E. Glover, Holger K. Eltzschig and Sean P. Colgan

J Immunol April 15, 2009, 182 (8) 4957-4964; DOI: https://doi.org/10.4049/jimmunol.0801324
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Heat Shock Protein 96 Is Elevated in Rheumatoid Arthritis and Activates Macrophages Primarily via TLR2 Signaling
Qi-Quan Huang, Rudina Sobkoviak, Angela R. Jockheck-Clark, Bo Shi, Arthur M. Mandelin II, Paul Peter Tak, G. Kennith Haines III, Christopher V. Nicchitta and Richard M. Pope

J Immunol April 15, 2009, 182 (8) 4965-4973; DOI: https://doi.org/10.4049/jimmunol.0801563
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Formyl Peptide Receptor-Like 2 Is Expressed and Functional in Plasmacytoid Dendritic Cells, Tissue-Specific Macrophage Subpopulations, and Eosinophils
Thalie Devosse, Aude Guillabert, Nicky D'Haene, Alix Berton, Patricia De Nadai, Sophie Noel, Maryse Brait, Jean-Denis Franssen, Silvano Sozzani, Isabelle Salmon and Marc Parmentier

J Immunol April 15, 2009, 182 (8) 4974-4984; DOI: https://doi.org/10.4049/jimmunol.0803128
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Role of the Heparan Sulfate Proteoglycan Syndecan-1 (CD138) in Delayed-Type Hypersensitivity
Behzad Kharabi Masouleh, Gerdy B. Ten Dam, Martin K. Wild, Ruth Seelige, Johan van der Vlag, Angelique L. Rops, Frank G. Echtermeyer, Dietmar Vestweber, Toin H. van Kuppevelt, Ludwig Kiesel and Martin Götte

J Immunol April 15, 2009, 182 (8) 4985-4993; DOI: https://doi.org/10.4049/jimmunol.0800574
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MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression
Thomas X. Lu, Ariel Munitz and Marc E. Rothenberg

J Immunol April 15, 2009, 182 (8) 4994-5002; DOI: https://doi.org/10.4049/jimmunol.0803560
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IL-20 Is Regulated by Hypoxia-Inducible Factor and Up-Regulated after Experimental Ischemic Stroke
Wei-Yu Chen and Ming-Shi Chang

J Immunol April 15, 2009, 182 (8) 5003-5012; DOI: https://doi.org/10.4049/jimmunol.0803653
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Functional Blocking Monoclonal Antibodies against IL-12p40 Homodimer Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis
Susanta Mondal, Avik Roy and Kalipada Pahan

J Immunol April 15, 2009, 182 (8) 5013-5023; DOI: https://doi.org/10.4049/jimmunol.0801734
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The Pattern Recognition Receptor CD36 Is a Chondrocyte Hypertrophy Marker Associated with Suppression of Catabolic Responses and Promotion of Repair Responses to Inflammatory Stimuli
Denise L. Cecil, C. Thomas G. Appleton, Monika D. Polewski, John S. Mort, Ann Marie Schmidt, Alison Bendele, Frank Beier and Robert Terkeltaub

J Immunol April 15, 2009, 182 (8) 5024-5031; DOI: https://doi.org/10.4049/jimmunol.0803603
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The Atypical Chemokine Receptor D6 Contributes to the Development of Experimental Colitis
Yvonne Bordon, Chris A. H. Hansell, David P. Sester, Mairi Clarke, Allan McI. Mowat and Robert J. B. Nibbs

J Immunol April 15, 2009, 182 (8) 5032-5040; DOI: https://doi.org/10.4049/jimmunol.0802802
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A Novel and Critical Role for Tyrosine 663 in Platelet Endothelial Cell Adhesion Molecule-1 Trafficking and Transendothelial Migration
Bidisha Dasgupta, Eric Dufour, Zahra Mamdouh and William A. Muller

J Immunol April 15, 2009, 182 (8) 5041-5051; DOI: https://doi.org/10.4049/jimmunol.0803192
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P2X7 Receptor-Stimulated Secretion of MHC Class II-Containing Exosomes Requires the ASC/NLRP3 Inflammasome but Is Independent of Caspase-1
Yan Qu, Lakshmi Ramachandra, Susanne Mohr, Luigi Franchi, Clifford V. Harding, Gabriel Nunez and George R. Dubyak

J Immunol April 15, 2009, 182 (8) 5052-5062; DOI: https://doi.org/10.4049/jimmunol.0802968
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p53 Attenuates Lipopolysaccharide-Induced NF-κB Activation and Acute Lung Injury
Gang Liu, Young-Jun Park, Yuko Tsuruta, Emmanuel Lorne and Edward Abraham

J Immunol April 15, 2009, 182 (8) 5063-5071; DOI: https://doi.org/10.4049/jimmunol.0803526
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Mitocryptide-2: Purification, Identification, and Characterization of a Novel Cryptide That Activates Neutrophils
Hidehito Mukai, Tetsuo Seki, Hiroko Nakano, Yoshinori Hokari, Toshifumi Takao, Masanori Kawanami, Hiroyuki Tsukagoshi, Hirokazu Kimura, Yoshiaki Kiso, Yasutsugu Shimonishi, Yoshisuke Nishi and Eisuke Munekata

J Immunol April 15, 2009, 182 (8) 5072-5080; DOI: https://doi.org/10.4049/jimmunol.0802965
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Adaptor Proteins and Ras Synergistically Regulate IL-1-Induced ADAMTS-4 Expression in Human Chondrocytes
Rasheed Ahmad, Judith Sylvester, Mushtaq Ahmad and Muhammad Zafarullah

J Immunol April 15, 2009, 182 (8) 5081-5087; DOI: https://doi.org/10.4049/jimmunol.0803544
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Bruton’s Tyrosine Kinase Is Involved in miR-346-Related Regulation of IL-18 Release by Lipopolysaccharide-Activated Rheumatoid Fibroblast-Like Synoviocytes
Ghada Alsaleh, Guillaume Suffert, Noha Semaan, Tom Juncker, Laurent Frenzel, Jacques-Eric Gottenberg, Jean Sibilia, Sébastien Pfeffer and Dominique Wachsmann

J Immunol April 15, 2009, 182 (8) 5088-5097; DOI: https://doi.org/10.4049/jimmunol.0801613
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Acidic Mammalian Chitinase Regulates Epithelial Cell Apoptosis via a Chitinolytic-Independent Mechanism
Dominik Hartl, Chuan Hua He, Babara Koller, Carla A. Da Silva, Yasushi Kobayashi, Chun Geun Lee, Richard A. Flavell and Jack A. Elias

J Immunol April 15, 2009, 182 (8) 5098-5106; DOI: https://doi.org/10.4049/jimmunol.0803446
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Pathogenesis of Steroid-Resistant Airway Hyperresponsiveness: Interaction between IFN-γ and TLR4/MyD88 Pathways
Ming Yang, Rakesh K. Kumar and Paul S. Foster

J Immunol April 15, 2009, 182 (8) 5107-5115; DOI: https://doi.org/10.4049/jimmunol.0803468
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Induction of Airway Hyperreactivity by IL-25 Is Dependent on a Subset of Invariant NKT Cells Expressing IL-17RB
Philippe Stock, Vincent Lombardi, Viola Kohlrautz and Omid Akbari

J Immunol April 15, 2009, 182 (8) 5116-5122; DOI: https://doi.org/10.4049/jimmunol.0804213
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A Protective Role for C5a in the Development of Allergic Asthma Associated with Altered Levels of B7-H1 and B7-DC on Plasmacytoid Dendritic Cells
Xun Zhang, Ian P. Lewkowich, Gabriele Köhl, Jennifer R. Clark, Marsha Wills-Karp and Jörg Köhl

J Immunol April 15, 2009, 182 (8) 5123-5130; DOI: https://doi.org/10.4049/jimmunol.0804276

CLINICAL IMMUNOLOGY

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HLA-DQ8 (DQB1*0302)-Restricted Th17 Cells Exacerbate Experimental Autoimmune Encephalomyelitis in HLA-DR3-Transgenic Mice
Ashutosh Mangalam, David Luckey, Eati Basal, Megan Jackson, Michele Smart, Moses Rodriguez and Chella David

J Immunol April 15, 2009, 182 (8) 5131-5139; DOI: https://doi.org/10.4049/jimmunol.0803918
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Enrichment of Human CD4⁺ Vα24/Vβ11 Invariant NKT Cells in Intrahepatic Malignant Tumors
Gabriel Bricard, Valerie Cesson, Estelle Devevre, Hanifa Bouzourene, Catherine Barbey, Nathalie Rufer, Jin S. Im, Pedro M. Alves, Olivier Martinet, Nermin Halkic, Jean-Charles Cerottini, Pedro Romero, Steven A. Porcelli, H. Robson MacDonald and Daniel E. Speiser

J Immunol April 15, 2009, 182 (8) 5140-5151; DOI: https://doi.org/10.4049/jimmunol.0711086

CORRECTIONS

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Extracellular granzymes A and B in humans: Detection of native species during CTL responses in vitro and in vivo
E. H. A. Spaeny-Dekking, W. L. Hanna, A. M. Wolbink, P. C. Wever, A. J. Kummer, A. J. G. Swaak, J. M. Middeldorp, H. G. Huisman, C. J. Froelich and C. E. Hack

J Immunol April 15, 2009, 182 (8) 5152; DOI: https://doi.org/10.4049/jimmunol.0990024
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Linking C5 deficiency to an exonic splicing enhancer mutation
N. Pfarr, D. Prawitt, M. Kirschfink, C. Schroff, M. Knuf, P. Habermehl, W. Mannhardt, F. Zepp, W. Fairbrother, M. Loos, C. B. Burge and J. Pohlenz

J Immunol April 15, 2009, 182 (8) 5152; DOI: https://doi.org/10.4049/jimmunol.0990023
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ISCOMATRIX adjuvant induces efficient cross-presentation of tumor Ag by dendritic cells via rapid cytosolic Ag delivery and processing via tripeptidyl peptidase II
M. Schnurr, M. Orban, N. C. Robson, A. Shin, H. Braley, D. Airey, J. Cebon, E. Maraskovsky and S. Endres

J Immunol April 15, 2009, 182 (8) 5152; DOI: https://doi.org/10.4049/jimmunol.0990022

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CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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