About the Cover
Cover image

On the cover: Biosensor-mediated tracking of RhoA activity during Toll receptor signaling as a tool for pathway elucidation. Basal RhoA GTPase activity in unstimulated lung epithelial cells is presented as CFP/FRET ratio image visualized by color-coding on a scale representing an increase of activity from purple to yellow and red. Manukyan, M., P. Nalbant, S. Luxen, K. M. Hahn, and U. G. Knaus. 2009. RhoA GTPase activation by TLR2 and TLR3 ligands: connecting via Src to NF-κB. J. Immunol. 182: 3522–3529.