The Journal of Immunology: 180 (9)

May 1, 2008; Volume 180,Issue 9

IN THIS ISSUE

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IN THIS ISSUE

J Immunol May 1, 2008, 180 (9) 5759-5760; DOI: https://doi.org/10.4049/jimmunol.180.9.5759

LETTERS TO THE EDITOR

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Comment on “Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent”
Tania Maes, Ken R. Bracke, Guy F. Joos and Guy G. Brusselle

J Immunol May 1, 2008, 180 (9) 5761; DOI: https://doi.org/10.4049/jimmunol.180.9.5761
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Response to Comment on “Cigarette Smoke-Induced Pulmonary Inflammation Is TLR4/MyD88 and IL-1R1/MyD88 Signaling Dependent”
Emilie Doz, Bernhard Ryffel, Valérie F. J. Quesniaux and Isabelle Couillin

J Immunol May 1, 2008, 180 (9) 5761; DOI: https://doi.org/10.4049/jimmunol.180.9.5761-a

PILLARS OF IMMUNOLOGY

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Tracking and Trapping Somatic Mutations in Ig Genes
Marko Radic

J Immunol May 1, 2008, 180 (9) 5763-5764; DOI: https://doi.org/10.4049/jimmunol.180.9.5763
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Pillars Article: Generation of Antibody Diversity in the Immune Response of BALB/c Mice to Influenza Virus Hemagglutinin. Proc. Natl. Acad. Sci. USA 1984. 81: 3180–3184.
David McKean, Konrad Huppi, Michael Bell, Louis Staudt, Walter Gerhard and Martin Weigert

J Immunol May 1, 2008, 180 (9) 5765-5769;

BRIEF REVIEWS

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IL-10: The Master Regulator of Immunity to Infection
Kevin N. Couper, Daniel G. Blount and Eleanor M. Riley

J Immunol May 1, 2008, 180 (9) 5771-5777; DOI: https://doi.org/10.4049/jimmunol.180.9.5771

CUTTING EDGE

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Cutting Edge: Membrane Nanotubes In Vivo: A Feature of MHC Class II⁺ Cells in the Mouse Cornea
Holly R. Chinnery, Eric Pearlman and Paul G. McMenamin

J Immunol May 1, 2008, 180 (9) 5779-5783; DOI: https://doi.org/10.4049/jimmunol.180.9.5779
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Cutting Edge: Dendritic Cells Prime a High Avidity CTL Response Independent of the Level of Presented Antigen
Charles J. Kroger, Samuel Amoah and Martha A. Alexander-Miller

J Immunol May 1, 2008, 180 (9) 5784-5788; DOI: https://doi.org/10.4049/jimmunol.180.9.5784
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Cutting Edge: Enhanced IL-2 Signaling Can Convert Self-Specific T Cell Response from Tolerance to Autoimmunity
Jason Waithman, Thomas Gebhardt, Gayle M. Davey, William R. Heath and Francis R. Carbone

J Immunol May 1, 2008, 180 (9) 5789-5793; DOI: https://doi.org/10.4049/jimmunol.180.9.5789
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Cutting Edge: Foxp3-Mediated Induction of Pim 2 Allows Human T Regulatory Cells to Preferentially Expand in Rapamycin
Samik Basu, Tatiana Golovina, Tatiana Mikheeva, Carl H. June and James L. Riley

J Immunol May 1, 2008, 180 (9) 5794-5798; DOI: https://doi.org/10.4049/jimmunol.180.9.5794
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Cutting Edge: Overlapping Functions of TLR7 and TLR9 for Innate Defense against a Herpesvirus Infection
Nicolas Zucchini, Gilles Bessou, Stephanie Traub, Scott H. Robbins, Satoshi Uematsu, Shizuo Akira, Lena Alexopoulou and Marc Dalod

J Immunol May 1, 2008, 180 (9) 5799-5803; DOI: https://doi.org/10.4049/jimmunol.180.9.5799

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Lck-Dependent Tyrosine Phosphorylation of Diacylglycerol Kinase α Regulates Its Membrane Association in T Cells
Ernesto Merino, Antonia Ávila-Flores, Yasuhito Shirai, Ignacio Moraga, Naoaki Saito and Isabel Mérida

J Immunol May 1, 2008, 180 (9) 5805-5815; DOI: https://doi.org/10.4049/jimmunol.180.9.5805
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Virus-Like Display of a Neo-Self Antigen Reverses B Cell Anergy in a B Cell Receptor Transgenic Mouse Model
Bryce Chackerian, Marisa R. Durfee and John T. Schiller

J Immunol May 1, 2008, 180 (9) 5816-5825; DOI: https://doi.org/10.4049/jimmunol.180.9.5816
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Danger Signaling through the Inflammasome Acts as a Master Switch between Tolerance and Sensitization
Hideki Watanabe, Samuel Gehrke, Emmanuel Contassot, Stéphanie Roques, Jürg Tschopp, Peter S. Friedmann, Lars E. French and Olivier Gaide

J Immunol May 1, 2008, 180 (9) 5826-5832; DOI: https://doi.org/10.4049/jimmunol.180.9.5826
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Conserved Mycobacterial Lipoglycoproteins Activate TLR2 but Also Require Glycosylation for MHC Class II-Restricted T Cell Activation
Peter A. Sieling, Preston J. Hill, Karen M. Dobos, Kerry Brookman, Andrew M. Kuhlman, Mario Fabri, Stephan R. Krutzik, Thomas H. Rea, Darragh G. Heaslip, John T. Belisle and Robert L. Modlin

J Immunol May 1, 2008, 180 (9) 5833-5842; DOI: https://doi.org/10.4049/jimmunol.180.9.5833
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Systemic Control of Plasmacytoid Dendritic Cells by CD8⁺ T Cells and Commensal Microbiota
Daisuke Fujiwara, Bo Wei, Laura L. Presley, Sarah Brewer, Michael McPherson, Michael A. Lewinski, James Borneman and Jonathan Braun

J Immunol May 1, 2008, 180 (9) 5843-5852; DOI: https://doi.org/10.4049/jimmunol.180.9.5843
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Pathogen Proliferation Governs the Magnitude but Compromises the Function of CD8 T Cells
Subash Sad, Renu Dudani, Komal Gurnani, Marsha Russell, Henk van Faassen, Brett Finlay and Lakshmi Krishnan

J Immunol May 1, 2008, 180 (9) 5853-5861; DOI: https://doi.org/10.4049/jimmunol.180.9.5853
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Differential Control of T Regulatory Cell Proliferation and Suppressive Activity by Mature Plasmacytoid versus Conventional Spleen Dendritic Cells
Asmahan Ouabed, Francois-Xavier Hubert, Dominique Chabannes, Laetitia Gautreau, Michèle Heslan and Régis Josien

J Immunol May 1, 2008, 180 (9) 5862-5870; DOI: https://doi.org/10.4049/jimmunol.180.9.5862
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Tumor-Induced Impairment of TCR Signaling Results in Compromised Functionality of Tumor-Infiltrating Regulatory T Cells
M. E. Christine Lutsiak, Yutaka Tagaya, Anthony J. Adams, Jeffrey Schlom and Helen Sabzevari

J Immunol May 1, 2008, 180 (9) 5871-5881; DOI: https://doi.org/10.4049/jimmunol.180.9.5871
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IFN-γ and IL-17 Production in Experimental Autoimmune Encephalomyelitis Depends on Local APC–T Cell Complement Production
Jinbo Liu, Feng Lin, Michael G. Strainic, Fengqi An, Robert H. Miller, Cengiz Z. Altuntas, Peter S. Heeger, Vincent K. Tuohy and M. Edward Medof

J Immunol May 1, 2008, 180 (9) 5882-5889; DOI: https://doi.org/10.4049/jimmunol.180.9.5882
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CD83 Expression in CD4⁺ T Cells Modulates Inflammation and Autoimmunity
Simone Reinwald, Carsten Wiethe, Astrid M. Westendorf, Minka Breloer, Michael Probst-Kepper, Bernhard Fleischer, Alexander Steinkasserer, Jan Buer and Wiebke Hansen

J Immunol May 1, 2008, 180 (9) 5890-5897; DOI: https://doi.org/10.4049/jimmunol.180.9.5890
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Deacetylase Activity Is Required for STAT5-Dependent GM-CSF Functional Activity in Macrophages and Differentiation to Dendritic Cells
Carlos Sebastián, Maria Serra, Andrée Yeramian, Neus Serrat, Jorge Lloberas and Antonio Celada

J Immunol May 1, 2008, 180 (9) 5898-5906; DOI: https://doi.org/10.4049/jimmunol.180.9.5898
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HIV-1-Specific T Cell Precursors with High Proliferative Capacity Correlate with Low Viremia and High CD4 Counts in Untreated Individuals
Sandra A. Calarota, Andrea Foli, Renato Maserati, Fausto Baldanti, Stefania Paolucci, Mary A. Young, Christos M. Tsoukas, Julianna Lisziewicz and Franco Lori

J Immunol May 1, 2008, 180 (9) 5907-5915; DOI: https://doi.org/10.4049/jimmunol.180.9.5907
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Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II
Bitao Liang, Craig Workman, Janine Lee, Claude Chew, Benjamin M. Dale, Lucrezia Colonna, Marcella Flores, Nianyu Li, Edina Schweighoffer, Steven Greenberg, Victor Tybulewicz, Dario Vignali and Raphael Clynes

J Immunol May 1, 2008, 180 (9) 5916-5926; DOI: https://doi.org/10.4049/jimmunol.180.9.5916
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Disruption of Mutually Negative Regulatory Feedback Loop between Interferon-Inducible p202 Protein and the E2F Family of Transcription Factors in Lupus-Prone Mice
Ravichandran Panchanathan, Hong Xin and Divaker Choubey

J Immunol May 1, 2008, 180 (9) 5927-5934; DOI: https://doi.org/10.4049/jimmunol.180.9.5927
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IL-12 Signaling Drives CD8⁺ T Cell IFN-γ Production and Differentiation of KLRG1⁺ Effector Subpopulations during Toxoplasma gondii Infection
Douglas C. Wilson, Suzanne Matthews and George S. Yap

J Immunol May 1, 2008, 180 (9) 5935-5945; DOI: https://doi.org/10.4049/jimmunol.180.9.5935
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An Interaction between CD200 and Monoclonal Antibody Agonists to CD200R2 in Development of Dendritic Cells That Preferentially Induce Populations of CD4⁺CD25⁺ T Regulatory Cells
Reg Gorczynski, Ismat Khatri, Lydia Lee and Ivo Boudakov

J Immunol May 1, 2008, 180 (9) 5946-5955; DOI: https://doi.org/10.4049/jimmunol.180.9.5946
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Conversion of Tyrosine to the Inflammation-Associated Analog 3′-Nitrotyrosine at Either TCR- or MHC-Contact Positions Can Profoundly Affect Recognition of the MHC Class I-Restricted Epitope of Lymphocytic Choriomeningitis Virus Glycoprotein 33 by CD8 T Cells
Lani L. Hardy, Darin A. Wick and John R. Webb

J Immunol May 1, 2008, 180 (9) 5956-5962; DOI: https://doi.org/10.4049/jimmunol.180.9.5956
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Plasmacytoid Dendritic Cells Migrate in Afferent Skin Lymph
Florentia Pascale, Vanessa Contreras, Michel Bonneau, Alexandre Courbet, Stefan Chilmonczyk, Claudia Bevilacqua, Mathieu Eparaud, Violeta Niborski, Sabine Riffault, Anne-Marie Balazuc, Eliane Foulon, Laurence Guzylack-Piriou, Beatrice Riteau, Jayne Hope, Nicolas Bertho, Bernard Charley and Isabelle Schwartz-Cornil

J Immunol May 1, 2008, 180 (9) 5963-5972; DOI: https://doi.org/10.4049/jimmunol.180.9.5963
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Preferential Development of CD4 and CD8 T Regulatory Cells in RasGRP1-Deficient Mice
Xiaoxi Chen, John J. Priatel, Michael T. Chow and Hung-Sia Teh

J Immunol May 1, 2008, 180 (9) 5973-5982; DOI: https://doi.org/10.4049/jimmunol.180.9.5973
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SUMOylation Regulates the Transcriptional Activity of JunB in T Lymphocytes
Johan Garaude, Rosa Farrás, Guillaume Bossis, Seyma Charni, Marc Piechaczyk, Robert A. Hipskind and Martin Villalba

J Immunol May 1, 2008, 180 (9) 5983-5990; DOI: https://doi.org/10.4049/jimmunol.180.9.5983
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Prevention of Allograft Tolerance by Bacterial Infection with Listeria monocytogenes
Tongmin Wang, Luqiu Chen, Emily Ahmed, Lianli Ma, Dengping Yin, Ping Zhou, Jikun Shen, Honglin Xu, Chyung-Ru Wang, Maria-Luisa Alegre and Anita S. Chong

J Immunol May 1, 2008, 180 (9) 5991-5999; DOI: https://doi.org/10.4049/jimmunol.180.9.5991
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Fungal Proteases Induce Th2 Polarization through Limited Dendritic Cell Maturation and Reduced Production of IL-12
Salah-Eddine Lamhamedi-Cherradi, Rachel Elizabeth Martin, Tomoki Ito, Farrah Kheradmand, David Brian Corry, Yong-Jun Liu and Matthew Moyle

J Immunol May 1, 2008, 180 (9) 6000-6009; DOI: https://doi.org/10.4049/jimmunol.180.9.6000
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Inorganic Arsenic Activates Reduced NADPH Oxidase in Human Primary Macrophages through a Rho Kinase/p38 Kinase Pathway
Anthony Lemarie, Emilie Bourdonnay, Claudie Morzadec, Olivier Fardel and Laurent Vernhet

J Immunol May 1, 2008, 180 (9) 6010-6017; DOI: https://doi.org/10.4049/jimmunol.180.9.6010
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Reovirus Activates Human Dendritic Cells to Promote Innate Antitumor Immunity
Fiona Errington, Lynette Steele, Robin Prestwich, Kevin J. Harrington, Hardev S. Pandha, Laura Vidal, Johann de Bono, Peter Selby, Matt Coffey, Richard Vile and Alan Melcher

J Immunol May 1, 2008, 180 (9) 6018-6026; DOI: https://doi.org/10.4049/jimmunol.180.9.6018
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Phospholipase D1 Plays a Key Role in TNF-α Signaling
Swaminathan Sethu, Grecia Mendez-Corao and Alirio J. Melendez

J Immunol May 1, 2008, 180 (9) 6027-6034; DOI: https://doi.org/10.4049/jimmunol.180.9.6027
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TLR6 Modulates First Trimester Trophoblast Responses to Peptidoglycan
Vikki M. Abrahams, Paulomi B. Aldo, Shaun P. Murphy, Irene Visintin, Kaori Koga, Gabriella Wilson, Roberto Romero, Surendra Sharma and Gil Mor

J Immunol May 1, 2008, 180 (9) 6035-6043; DOI: https://doi.org/10.4049/jimmunol.180.9.6035
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Protective Immunosurveillance and Therapeutic Antitumor Activity of γδ T Cells Demonstrated in a Mouse Model of Prostate Cancer
Zhiyong Liu, Isam-Eldin A. Eltoum, Ben Guo, Benjamin H. Beck, Gretchen A. Cloud and Richard D. Lopez

J Immunol May 1, 2008, 180 (9) 6044-6053; DOI: https://doi.org/10.4049/jimmunol.180.9.6044
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Characterization of IL-10-Secreting T Cells Derived from Regulatory CD4⁺CD25⁺ Cells by the TIRC7 Surface Marker
Abdelilah Wakkach, Séverine Augier, Jean-Philippe Breittmayer, Claudine Blin-Wakkach and Georges F. Carle

J Immunol May 1, 2008, 180 (9) 6054-6063; DOI: https://doi.org/10.4049/jimmunol.180.9.6054
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Suppression of Normal and Malignant Kit Signaling by a Bispecific Antibody Linking Kit with CD300a
Ido Bachelet, Ariel Munitz, Beata Berent-Maoz, David Mankuta and Francesca Levi-Schaffer

J Immunol May 1, 2008, 180 (9) 6064-6069; DOI: https://doi.org/10.4049/jimmunol.180.9.6064
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Loss of STAT3 in CD4⁺ T Cells Prevents Development of Experimental Autoimmune Diseases
Xuebin Liu, Yun Sang Lee, Cheng-Rong Yu and Charles E. Egwuagu

J Immunol May 1, 2008, 180 (9) 6070-6076; DOI: https://doi.org/10.4049/jimmunol.180.9.6070
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Long-Term Control of Alloreactive B Cell Responses by the Suppression of T Cell Help
Yijin Li, Lianli Ma, Dengping Yin, JiKun Shen and Anita S. Chong

J Immunol May 1, 2008, 180 (9) 6077-6084; DOI: https://doi.org/10.4049/jimmunol.180.9.6077
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Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Inhibits Proximal TCR Signaling by Targeting ZAP-70
Zhangguo Chen, Lanfen Chen, Shuo-Wang Qiao, Takashi Nagaishi and Richard S. Blumberg

J Immunol May 1, 2008, 180 (9) 6085-6093; DOI: https://doi.org/10.4049/jimmunol.180.9.6085

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Antigen Receptor Editing in Anti-DNA Transitional B Cells Deficient for Surface IgM
Kerstin Kiefer, Pamela B. Nakajima, Jennifer Oshinsky, Steven H. Seeholzer, Marko Radic, Gayle C. Bosma and Melvin J. Bosma

J Immunol May 1, 2008, 180 (9) 6094-6106; DOI: https://doi.org/10.4049/jimmunol.180.9.6094
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Functional Activity of MD-2 Polymorphic Variant Is Significantly Different in Soluble and TLR4-Bound Forms: Decreased Endotoxin Binding by G56R MD-2 and Its Rescue by TLR4 Ectodomain
Jožica Vašl, Polonca Prohinar, Theresa L. Gioannini, Jerrold P. Weiss and Roman Jerala

J Immunol May 1, 2008, 180 (9) 6107-6115; DOI: https://doi.org/10.4049/jimmunol.180.9.6107
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Single and Dual Amino Acid Substitutions in TCR CDRs Can Enhance Antigen-Specific T Cell Functions
Paul F. Robbins, Yong F. Li, Mona El-Gamil, Yangbing Zhao, Jennifer A. Wargo, Zhili Zheng, Hui Xu, Richard A. Morgan, Steven A. Feldman, Laura A. Johnson, Alan D. Bennett, Steven M. Dunn, Tara M. Mahon, Bent K. Jakobsen and Steven A. Rosenberg

J Immunol May 1, 2008, 180 (9) 6116-6131; DOI: https://doi.org/10.4049/jimmunol.180.9.6116
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Mannose-Binding Lectin (MBL)-Associated Serine Protease (MASP)-1 Contributes to Activation of the Lectin Complement Pathway
Minoru Takahashi, Daisuke Iwaki, Kazuko Kanno, Yumi Ishida, Jie Xiong, Misao Matsushita, Yuichi Endo, Shigeto Miura, Naoto Ishii, Kazuo Sugamura and Teizo Fujita

J Immunol May 1, 2008, 180 (9) 6132-6138; DOI: https://doi.org/10.4049/jimmunol.180.9.6132

IMMUNOGENETICS

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Immunological and Genetic Evidence for a Crucial Role of IL-10 in Cutaneous Lesions in Humans Infected with Leishmania braziliensis
Adnene Salhi, Virmondes Rodrigues Jr., Ferrucio Santoro, Helia Dessein, Audrey Romano, Lucio Roberto Castellano, Mathieu Sertorio, Sima Rafati, Christophe Chevillard, Aluisio Prata, Alexandre Alcaïs, Laurent Argiro and Alain Dessein

J Immunol May 1, 2008, 180 (9) 6139-6148; DOI: https://doi.org/10.4049/jimmunol.180.9.6139

HOST DEFENSE

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Lipoproteins Are Critical TLR2 Activating Toxins in Group B Streptococcal Sepsis
Philipp Henneke, Shaynoor Dramsi, Giuseppe Mancuso, Kamila Chraibi, Elisabeth Pellegrini, Christian Theilacker, Johannes Hübner, Sandra Santos-Sierra, Giuseppe Teti, Douglas T. Golenbock, Claire Poyart and Patrick Trieu-Cuot

J Immunol May 1, 2008, 180 (9) 6149-6158; DOI: https://doi.org/10.4049/jimmunol.180.9.6149
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A DNA Vaccine Prime Followed by a Liposome-Encapsulated Protein Boost Confers Enhanced Mucosal Immune Responses and Protection
Kejian Yang, Barbara J. Whalen, Rebecca S. Tirabassi, Liisa K. Selin, Tatyana S. Levchenko, Vladimir P. Torchilin, Edward H. Kislauskis and Dennis L. Guberski

J Immunol May 1, 2008, 180 (9) 6159-6167; DOI: https://doi.org/10.4049/jimmunol.180.9.6159
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Alternatively Activated Myeloid Cells Limit Pathogenicity Associated with African Trypanosomiasis through the IL-10 Inducible Gene Selenoprotein P
Tom Bosschaerts, Martin Guilliams, Wim Noel, Michel Hérin, Raymond F. Burk, Kristina E. Hill, Lea Brys, Geert Raes, Gholamreza Hassanzadeh Ghassabeh, Patrick De Baetselier and Alain Beschin

J Immunol May 1, 2008, 180 (9) 6168-6175; DOI: https://doi.org/10.4049/jimmunol.180.9.6168
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Neisseria gonorrhoeae-Induced Human Defensins 5 and 6 Increase HIV Infectivity: Role in Enhanced Transmission
Mary E. Klotman, Aprille Rapista, Natalia Teleshova, Amanda Micsenyi, Gary A. Jarvis, Wuyuan Lu, Edith Porter and Theresa L. Chang

J Immunol May 1, 2008, 180 (9) 6176-6185; DOI: https://doi.org/10.4049/jimmunol.180.9.6176
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Tick Saliva Inhibits Dendritic Cell Migration, Maturation, and Function while Promoting Development of Th2 Responses
Anna Skallová, Giandomenica Iezzi, Franziska Ampenberger, Manfred Kopf and Jan Kopecký

J Immunol May 1, 2008, 180 (9) 6186-6192; DOI: https://doi.org/10.4049/jimmunol.180.9.6186
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T Cell Response Mediated by Myeloid Cell-Derived IL-12 Is Responsible for Porphyromonas gingivalis-Induced Periodontitis in IL-10-Deficient Mice
Hajime Sasaki, Noriyuki Suzuki, Ralph Kent Jr., Nobuyuki Kawashima, Junji Takeda and Philip Stashenko

J Immunol May 1, 2008, 180 (9) 6193-6198; DOI: https://doi.org/10.4049/jimmunol.180.9.6193
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Inhibition of Yin Yang 1-Dependent Repressor Activity of DR5 Transcription and Expression by the Novel Proteasome Inhibitor NPI-0052 Contributes to its TRAIL-Enhanced Apoptosis in Cancer Cells
Stavroula Baritaki, Eriko Suzuki, Kazuo Umezawa, Demetrios A. Spandidos, James Berenson, Tracy R. Daniels, Manuel L. Penichet, Ali R. Jazirehi, Michael Palladino and Benjamin Bonavida

J Immunol May 1, 2008, 180 (9) 6199-6210; DOI: https://doi.org/10.4049/jimmunol.180.9.6199
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Leukotriene B₄ Induces Release of Antimicrobial Peptides in Lungs of Virally Infected Mice
Éric Gaudreault and Jean Gosselin

J Immunol May 1, 2008, 180 (9) 6211-6221; DOI: https://doi.org/10.4049/jimmunol.180.9.6211
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Bactericidal Action of a Complement-Independent Antibody against Relapsing Fever Borrelia Resides in Its Variable Region
Timothy J. LaRocca, Laura I. Katona, David G. Thanassi and Jorge L. Benach

J Immunol May 1, 2008, 180 (9) 6222-6228; DOI: https://doi.org/10.4049/jimmunol.180.9.6222
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Plasmacytoid Dendritic Cells Are Activated by Toxoplasma gondii to Present Antigen and Produce Cytokines
Marion Pepper, Florence Dzierszinski, Emma Wilson, Elia Tait, Qun Fang, Felix Yarovinsky, Terri M. Laufer, David Roos and Christopher A. Hunter

J Immunol May 1, 2008, 180 (9) 6229-6236; DOI: https://doi.org/10.4049/jimmunol.180.9.6229
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Chlamydia muridarum Evades Growth Restriction by the IFN-γ-Inducible Host Resistance Factor Irgb10
Jörn Coers, Isaac Bernstein-Hanley, David Grotsky, Iana Parvanova, Jonathan C. Howard, Gregory A. Taylor, William F. Dietrich and Michael N. Starnbach

J Immunol May 1, 2008, 180 (9) 6237-6245; DOI: https://doi.org/10.4049/jimmunol.180.9.6237
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Neutrophil-Toxin Interactions Promote Antigen Delivery and Mucosal Clearance of Streptococcus pneumoniae
Kathryn A. Matthias, Aoife M. Roche, Alistair J. Standish, Mikhail Shchepetov and Jeffrey N. Weiser

J Immunol May 1, 2008, 180 (9) 6246-6254; DOI: https://doi.org/10.4049/jimmunol.180.9.6246
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Pattern Recognition Molecule Mindin Promotes Intranasal Clearance of Influenza Viruses
Wei Jia, Hong Li and You-Wen He

J Immunol May 1, 2008, 180 (9) 6255-6261; DOI: https://doi.org/10.4049/jimmunol.180.9.6255

INFLAMMATION

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Identification of Pendrin as a Common Mediator for Mucus Production in Bronchial Asthma and Chronic Obstructive Pulmonary Disease
Isao Nakao, Sachiko Kanaji, Shoichiro Ohta, Hidetomo Matsushita, Kazuhiko Arima, Noriko Yuyama, Mutsuo Yamaya, Katsutoshi Nakayama, Hiroshi Kubo, Mika Watanabe, Hironori Sagara, Kumiya Sugiyama, Hiroyuki Tanaka, Shuji Toda, Hiroaki Hayashi, Hiromasa Inoue, Tomoaki Hoshino, Aya Shiraki, Makoto Inoue, Koichi Suzuki, Hisamichi Aizawa, Satoshi Okinami, Hiroichi Nagai, Mamoru Hasegawa, Takeshi Fukuda, Eric D. Green and Kenji Izuhara

J Immunol May 1, 2008, 180 (9) 6262-6269; DOI: https://doi.org/10.4049/jimmunol.180.9.6262
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Unique Expression of Suppressor of Cytokine Signaling 3 Is Essential for Classical Macrophage Activation in Rodents In Vitro and In Vivo
Yu Liu, Keith N. Stewart, Eileen Bishop, Carylyn J. Marek, David C. Kluth, Andrew J. Rees and Heather M. Wilson

J Immunol May 1, 2008, 180 (9) 6270-6278; DOI: https://doi.org/10.4049/jimmunol.180.9.6270
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Requirement for Vav Proteins in Post-Recruitment Neutrophil Cytotoxicity in IgG but Not Complement C3-Dependent Injury
Ahmad Utomo, Junichi Hirahashi, Divya Mekala, Kenichi Asano, Michael Glogauer, Xavier Cullere and Tanya N. Mayadas

J Immunol May 1, 2008, 180 (9) 6279-6287; DOI: https://doi.org/10.4049/jimmunol.180.9.6279
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CD73-Generated Adenosine Restricts Lymphocyte Migration into Draining Lymph Nodes
Masahide Takedachi, Dongfeng Qu, Yukihiko Ebisuno, Hiroyuki Oohara, Michelle L. Joachims, Stephanie T. McGee, Emiko Maeda, Rodger P. McEver, Toshiyuki Tanaka, Masayuki Miyasaka, Shinya Murakami, Thomas Krahn, Michael R. Blackburn and Linda F. Thompson

J Immunol May 1, 2008, 180 (9) 6288-6296; DOI: https://doi.org/10.4049/jimmunol.180.9.6288
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IL-10 and Natural Regulatory T Cells: Two Independent Anti-Inflammatory Mechanisms in Herpes Simplex Virus-Induced Ocular Immunopathology
Pranita P. Sarangi, Sharvan Sehrawat, Susmit Suvas and Barry T. Rouse

J Immunol May 1, 2008, 180 (9) 6297-6306; DOI: https://doi.org/10.4049/jimmunol.180.9.6297
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Generation of Anaphylatoxins by Human β-Tryptase from C3, C4, and C5
Yoshihiro Fukuoka, Han-Zhang Xia, Laura B. Sanchez-Muñoz, Anthony L. Dellinger, Luis Escribano and Lawrence B. Schwartz

J Immunol May 1, 2008, 180 (9) 6307-6316; DOI: https://doi.org/10.4049/jimmunol.180.9.6307
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TLR2-Mediated Activation of Neutrophils in Response to German Cockroach Frass
Kristen Page, Kristin M. Lierl, Valerie S. Hughes, Ping Zhou, John R. Ledford and Marsha Wills-Karp

J Immunol May 1, 2008, 180 (9) 6317-6324; DOI: https://doi.org/10.4049/jimmunol.180.9.6317
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IL-27 Activates Human Monocytes via STAT1 and Suppresses IL-10 Production but the Inflammatory Functions of IL-27 Are Abrogated by TLRs and p38
George D. Kalliolias and Lionel B. Ivashkiv

J Immunol May 1, 2008, 180 (9) 6325-6333; DOI: https://doi.org/10.4049/jimmunol.180.9.6325
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NK but Not CD1-Restricted NKT Cells Facilitate Systemic Inflammation during Polymicrobial Intra-Abdominal Sepsis
Anthony O. Etogo, Jesus Nunez, Cheng Y. Lin, Tracy E. Toliver-Kinsky and Edward R. Sherwood

J Immunol May 1, 2008, 180 (9) 6334-6345; DOI: https://doi.org/10.4049/jimmunol.180.9.6334
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Cytokine Secretion Depends on Galα(1,3)Gal Expression in a Pig-to-Human Whole Blood Model
Marit Sæthre, Mårten K. J. Schneider, John D. Lambris, Paola Magotti, Guttorm Haraldsen, Jörg D. Seebach and Tom E. Mollnes

J Immunol May 1, 2008, 180 (9) 6346-6353; DOI: https://doi.org/10.4049/jimmunol.180.9.6346

CLINICAL IMMUNOLOGY

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Use of Allograft Biopsies to Assess Thymopoiesis after Thymus Transplantation
M. Louise Markert, Jie Li, Blythe H. Devlin, Jeffrey C. Hoehner, Henry E. Rice, Michael A. Skinner, Yi-Ju Li and Laura P. Hale

J Immunol May 1, 2008, 180 (9) 6354-6364; DOI: https://doi.org/10.4049/jimmunol.180.9.6354
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An Inducible Caspase 9 Safety Switch Can Halt Cell Therapy-Induced Autoimmune Disease
Moniek A. de Witte, Annelies Jorritsma, Erwin Swart, Karin C. Straathof, Karin de Punder, John B. A. G. Haanen, Cliona M. Rooney and Ton N. M. Schumacher

J Immunol May 1, 2008, 180 (9) 6365-6373; DOI: https://doi.org/10.4049/jimmunol.180.9.6365
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Humoral Immune Responses against the Immature Laminin Receptor Protein Show Prognostic Significance in Patients with Chronic Lymphocytic Leukemia
Birte Friedrichs, Sandra Siegel, Marita Kloess, Adel Barsoum, Joseph Coggin Jr., James Rohrer, Ilja Jakob, Markus Tiemann, Klaus Heidorn, Christoph Schulte, Dieter Kabelitz, Jörg Steinmann, Norbert Schmitz and Matthias Zeis

J Immunol May 1, 2008, 180 (9) 6374-6384; DOI: https://doi.org/10.4049/jimmunol.180.9.6374
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A Novel Non-Synonymous Polymorphism (p.Arg240His) in C4b-Binding Protein Is Associated with Atypical Hemolytic Uremic Syndrome and Leads to Impaired Alternative Pathway Cofactor Activity
Anna M. Blom, Frida Bergström, Matthew Edey, Martha Diaz-Torres, David Kavanagh, Anne Lampe, Judith A. Goodship, Lisa Strain, Nadeem Moghal, Mary McHugh, Carol Inward, Charles Tomson, Véronique Frémeaux-Bacchi, Bruno O. Villoutreix and Timothy H. J. Goodship

J Immunol May 1, 2008, 180 (9) 6385-6391; DOI: https://doi.org/10.4049/jimmunol.180.9.6385
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Blocking NK Cell Inhibitory Self-Recognition Promotes Antibody-Dependent Cellular Cytotoxicity in a Model of Anti-Lymphoma Therapy
Liat Binyamin, R. Katherine Alpaugh, Tracey L. Hughes, Charles T. Lutz, Kerry S. Campbell and Louis M. Weiner

J Immunol May 1, 2008, 180 (9) 6392-6401; DOI: https://doi.org/10.4049/jimmunol.180.9.6392
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Correlation of Blood T Cell and Antibody Reactivity to Myelin Proteins with HLA Type and Lesion Localization in Multiple Sclerosis
Judith M. Greer, Peter A. Csurhes, Diane M. Muller and Michael P. Pender

J Immunol May 1, 2008, 180 (9) 6402-6410; DOI: https://doi.org/10.4049/jimmunol.180.9.6402
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Natural Naive CD4⁺CD25⁺CD127^low Regulatory T Cell (Treg) Development and Function Are Disturbed in Multiple Sclerosis Patients: Recovery of Memory Treg Homeostasis during Disease Progression
Koen Venken, Niels Hellings, Tom Broekmans, Karen Hensen, Jean-Luc Rummens and Piet Stinissen

J Immunol May 1, 2008, 180 (9) 6411-6420; DOI: https://doi.org/10.4049/jimmunol.180.9.6411
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Decreased Expression of the Fractalkine Receptor CX3CR1 on Circulating Monocytes as New Feature of Sepsis-Induced Immunosuppression
Alexandre Pachot, Marie-Angélique Cazalis, Fabienne Venet, Fanny Turrel, Caroline Faudot, Nicolas Voirin, Jennifer Diasparra, Naïck Bourgoin, Françoise Poitevin, Bruno Mougin, Alain Lepape and Guillaume Monneret

J Immunol May 1, 2008, 180 (9) 6421-6429; DOI: https://doi.org/10.4049/jimmunol.180.9.6421

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