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The Journal of Immunology

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About the Cover

April 1, 2008; Volume 180,Issue 7

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On the cover: Integrin αLβ2 mediates leukocyte adhesion and migration on cells expressing the intercellular adhesion molecules (ICAMs). Transition of αLβ2 from a bent conformation (illustrated) to an extended conformation is a hallmark of αLβ2 activation and the opening of the αLβ2 headpiece could fine regulate the binding of αLβ2 to different ICAMs.Tang, X.-Y., Y.-F. Li, and S.-M. Tan. 2008. Intercellular adhesion molecule-3 binding of integrin αLβ2 requires both extension and opening of the integrin headpiece. J. Immunol. 180: 4793–4804.

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This Issue

The Journal of Immunology: 180 (7)
The Journal of Immunology
Vol. 180, Issue 7
1 Apr 2008
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  • IN THIS ISSUE
  • PILLARS OF IMMUNOLOGY
  • BRIEF REVIEWS
  • CUTTING EDGE
  • CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • HOST DEFENSE
  • INFLAMMATION
  • CLINICAL IMMUNOLOGY
  • Highlights
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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Print ISSN 0022-1767        Online ISSN 1550-6606