On the cover: Nonaka, M., B. Y. Ma, R. Murai, N. Nakamura, M. Baba, N. Kawasaki, K. Hodohara, S. Asano, and T. Kawasaki. 2008. Glycosylation-dependent interactions of C-type lectin DC-SIGN with colorectal tumor-associated Lewis glycans impair the function and differentiation of monocyte-derived dendritic cells. Immunohistochemistry of human moderately differentiated sigmoid colon adenocarcinoma. The deparaffinized cryosection was stained with anti-DC-SIGN (green) and anti-Lea glycan (red) mAbs. The association of DC-SIGN-expressing DCs with colon adenocarcinoma epithelia expressing Lea glycans in situ was visualized by confocal microscopy. J. Immunol. 180: 3347–3356.