The Journal of Immunology: 179 (10)

November 15, 2007; Volume 179,Issue 10

IN THIS ISSUE

Open Access
IN THIS ISSUE

The Journal of Immunology November 15, 2007, 179 (10) 6377-6378; DOI: https://doi.org/10.4049/jimmunol.179.10.6377

CUTTING EDGE

Open Access
Cutting Edge: Identification of a Pre-Ligand Assembly Domain (PLAD) and Ligand Binding Site in the IL-17 Receptor
Jill M. Kramer, Walter Hanel, Fang Shen, Nilgun Isik, James P. Malone, Amarnath Maitra, Wade Sigurdson, David Swart, Joel Tocker, Tian Jin and Sarah L. Gaffen

The Journal of Immunology November 15, 2007, 179 (10) 6379-6383; DOI: https://doi.org/10.4049/jimmunol.179.10.6379
Open Access
Cutting Edge: Rac GTPases Sensitize Activated T Cells to Die via Fas
Madhu Ramaswamy, Celine Dumont, Anthony C. Cruz, Jagan R. Muppidi, Timothy S. Gomez, Daniel D. Billadeau, Victor L. J. Tybulewicz and Richard M. Siegel

The Journal of Immunology November 15, 2007, 179 (10) 6384-6388; DOI: https://doi.org/10.4049/jimmunol.179.10.6384

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

Open Access
Tolerance Induction in Presensitized Bone Marrow Recipients by Veto CTLs: Effective Deletion of Host Anti-Donor Memory Effector Cells
Shlomit Reich-Zeliger, Esther Bachar-Lustig, Avichai Bar-Ilan and Yair Reisner

The Journal of Immunology November 15, 2007, 179 (10) 6389-6394; DOI: https://doi.org/10.4049/jimmunol.179.10.6389
Open Access
Differentiation and Ig-Allele Switch in Cell Line WEHI-231
Freia J. X. Spillmann, Gabriele Beck-Engeser and Matthias Wabl

The Journal of Immunology November 15, 2007, 179 (10) 6395-6402; DOI: https://doi.org/10.4049/jimmunol.179.10.6395
Open Access
Age-Related Defects in Moesin/Ezrin Cytoskeletal Signals in Mouse CD4 T Cells
Gonzalo G. Garcia, Amir A. Sadighi Akha and Richard A. Miller

The Journal of Immunology November 15, 2007, 179 (10) 6403-6409; DOI: https://doi.org/10.4049/jimmunol.179.10.6403
Open Access
Temporal and Spatial Changes of Histone 3 K4 Dimethylation at the IFN-γ Gene during Th1 and Th2 Cell Differentiation
Heli K. Hamalainen-Laanaya, James J. Kobie, Chawnshang Chang and Wei-ping Zeng

The Journal of Immunology November 15, 2007, 179 (10) 6410-6415; DOI: https://doi.org/10.4049/jimmunol.179.10.6410
Open Access
The Activating Immunoreceptor NKG2D and Its Ligands Are Involved in Allograft Transplant Rejection
Jim Kim, Catherine K. Chang, Tracy Hayden, Feng-Chun Liu, Jonathan Benjamin, Jessica A. Hamerman, Lewis L. Lanier and Sang-Mo Kang

The Journal of Immunology November 15, 2007, 179 (10) 6416-6420; DOI: https://doi.org/10.4049/jimmunol.179.10.6416
Open Access
Augmentation of Antigen-Presenting and Th1-Promoting Functions of Dendritic Cells by WSX-1(IL-27R) Deficiency
Sen Wang, Yoshiyuki Miyazaki, Yukari Shinozaki and Hiroki Yoshida

The Journal of Immunology November 15, 2007, 179 (10) 6421-6428; DOI: https://doi.org/10.4049/jimmunol.179.10.6421
Open Access
Differences in Expression, Affinity, and Function of Soluble (s)IL-4Rα and sIL-13Rα2 Suggest Opposite Effects on Allergic Responses
Marat Khodoun, Christina Lewis, Jun-Qi Yang, Tatyana Orekov, Crystal Potter, Thomas Wynn, Margaret Mentink-Kane, Gurjit K. Khurana Hershey, Marsha Wills-Karp and Fred D. Finkelman

The Journal of Immunology November 15, 2007, 179 (10) 6429-6438; DOI: https://doi.org/10.4049/jimmunol.179.10.6429
Open Access
Preferential Migration of T Regulatory Cells Induced by IL-16
Caroline McFadden, Ross Morgan, Shilpa Rahangdale, Daniel Green, Hisato Yamasaki, David Center and William Cruikshank

The Journal of Immunology November 15, 2007, 179 (10) 6439-6445; DOI: https://doi.org/10.4049/jimmunol.179.10.6439
Open Access
IL-4 Suppresses Dendritic Cell Response to Type I Interferons
Uma Sriram, Chhanda Biswas, Edward M. Behrens, Joudy-Ann Dinnall, Debra K. Shivers, Marc Monestier, Yair Argon and Stefania Gallucci

The Journal of Immunology November 15, 2007, 179 (10) 6446-6455; DOI: https://doi.org/10.4049/jimmunol.179.10.6446
Open Access
The Requirement of Reversible Cysteine Sulfenic Acid Formation for T Cell Activation and Function
Ryan D. Michalek, Kimberly J. Nelson, Beth C. Holbrook, John S. Yi, Daya Stridiron, Larry W. Daniel, Jacquelyn S. Fetrow, S. Bruce King, Leslie B. Poole and Jason M. Grayson

The Journal of Immunology November 15, 2007, 179 (10) 6456-6467; DOI: https://doi.org/10.4049/jimmunol.179.10.6456
Open Access
Select Plant Tannins Induce IL-2Rα Up-Regulation and Augment Cell Division in γδ T Cells
Jeff Holderness, Larissa Jackiw, Emily Kimmel, Hannah Kerns, Miranda Radke, Jodi F. Hedges, Charles Petrie, Patrick McCurley, Pati M. Glee, Aiyappa Palecanda and Mark A. Jutila

The Journal of Immunology November 15, 2007, 179 (10) 6468-6478; DOI: https://doi.org/10.4049/jimmunol.179.10.6468
Open Access
Leflunomide Inhibits PDK1/Akt Pathway and Induces Apoptosis of Human Mast Cells
Norifumi Sawamukai, Kazuyoshi Saito, Kunihiro Yamaoka, Shingo Nakayamada, Chisei Ra and Yoshiya Tanaka

The Journal of Immunology November 15, 2007, 179 (10) 6479-6484; DOI: https://doi.org/10.4049/jimmunol.179.10.6479
Open Access
CCR7 Signaling Inhibits T Cell Proliferation
Ekkehard Ziegler, Martin Oberbarnscheidt, Silvia Bulfone-Paus, Reinhold Förster, Ulrich Kunzendorf and Stefan Krautwald

The Journal of Immunology November 15, 2007, 179 (10) 6485-6493; DOI: https://doi.org/10.4049/jimmunol.179.10.6485
Open Access
Memory CD8⁺ T Cells Require CD28 Costimulation
Annie B. Borowski, Alina C. Boesteanu, Yvonne M. Mueller, Caterina Carafides, David J. Topham, John D. Altman, Stephen R. Jennings and Peter D. Katsikis

The Journal of Immunology November 15, 2007, 179 (10) 6494-6503; DOI: https://doi.org/10.4049/jimmunol.179.10.6494
Open Access
Requirement for Both JAK-Mediated PI3K Signaling and ACT1/TRAF6/TAK1-Dependent NF-κB Activation by IL-17A in Enhancing Cytokine Expression in Human Airway Epithelial Cells
Fei Huang, Cheng-Yuan Kao, Shinichiro Wachi, Philip Thai, Jisu Ryu and Reen Wu

The Journal of Immunology November 15, 2007, 179 (10) 6504-6513; DOI: https://doi.org/10.4049/jimmunol.179.10.6504
Open Access
CD4⁺CD28^null T Cells in Autoimmune Disease: Pathogenic Features and Decreased Susceptibility to Immunoregulation
Marielle Thewissen, Veerle Somers, Niels Hellings, Judith Fraussen, Jan Damoiseaux and Piet Stinissen

The Journal of Immunology November 15, 2007, 179 (10) 6514-6523; DOI: https://doi.org/10.4049/jimmunol.179.10.6514
Open Access
The Lipopolysaccharide Adjuvant Effect on T Cells Relies on Nonoverlapping Contributions from the MyD88 Pathway and CD11c⁺ Cells
Jeremy P. McAleer, David J. Zammit, Leo Lefrançois, Robert J. Rossi and Anthony T. Vella

The Journal of Immunology November 15, 2007, 179 (10) 6524-6535; DOI: https://doi.org/10.4049/jimmunol.179.10.6524
Open Access
IL-1α and IL-1β Are Endogenous Mediators Linking Cell Injury to the Adaptive Alloimmune Response
Deepak A. Rao, Kevin J. Tracey and Jordan S. Pober

The Journal of Immunology November 15, 2007, 179 (10) 6536-6546; DOI: https://doi.org/10.4049/jimmunol.179.10.6536
Open Access
Naive and Memory T Cells Induce Different Types of Graft-versus-Host Disease
Suparna Dutt, Diane Tseng, Joerg Ermann, Tracy I. George, Yin Ping Liu, Corrine R. Davis, C. Garrison Fathman and Samuel Strober

The Journal of Immunology November 15, 2007, 179 (10) 6547-6554; DOI: https://doi.org/10.4049/jimmunol.179.10.6547
Open Access
Spontaneous Class Switch Recombination in B Cell Lymphopoiesis Generates Aberrant Switch Junctions and Is Increased after VDJ Rearrangement
Efrat Edry, Sergei B. Koralov, Klaus Rajewsky and Doron Melamed

The Journal of Immunology November 15, 2007, 179 (10) 6555-6560; DOI: https://doi.org/10.4049/jimmunol.179.10.6555
Open Access
Intrahepatic Lymphocyte Expression of Dipeptidyl Peptidase I-Processed Granzyme B and Perforin Induces Hepatocyte Expression of Serine Proteinase Inhibitor 6 (Serpinb9/SPI-6)
Heather W. Stout-Delgado, Yonas Getachew, Bonnie C. Miller and Dwain L. Thiele

The Journal of Immunology November 15, 2007, 179 (10) 6561-6567; DOI: https://doi.org/10.4049/jimmunol.179.10.6561
Open Access
The Bw Cells, a Novel B Cell Population Conserved in the Whole Genus Mus
Aude Thiriot, Anne-Marie Drapier, Paulo Vieira, Catherine Fitting, Jean-Marc Cavaillon, Pierre-André Cazenave and Dominique Rueff-Juy

The Journal of Immunology November 15, 2007, 179 (10) 6568-6578; DOI: https://doi.org/10.4049/jimmunol.179.10.6568
Open Access
Donor Bone Marrow Type II (Non-Vα14Jα18 CD1d-Restricted) NKT Cells Suppress Graft-Versus-Host Disease by Producing IFN-γ and IL-4
Ji Hyung Kim, Eun Young Choi and Doo Hyun Chung

The Journal of Immunology November 15, 2007, 179 (10) 6579-6587; DOI: https://doi.org/10.4049/jimmunol.179.10.6579
Open Access
Secretory Leukoprotease Inhibitor in Mucosal Lymph Node Dendritic Cells Regulates the Threshold for Mucosal Tolerance
Janneke N. Samsom, Arnold P. J. van der Marel, Lisette A. van Berkel, Joop M. L. M. van Helvoort, Ytje Simons-Oosterhuis, Wendy Jansen, Mascha Greuter, Rob L. H. Nelissen, Cees M. L. Meeuwisse, Edward E. S. Nieuwenhuis, Reina E. Mebius and Georg Kraal

The Journal of Immunology November 15, 2007, 179 (10) 6588-6595; DOI: https://doi.org/10.4049/jimmunol.179.10.6588
Open Access
A Proximal κB Site in the IL-23 p19 Promoter Is Responsible for RelA- and c-Rel-Dependent Transcription
Setsuko Mise-Omata, Etsushi Kuroda, Junko Niikura, Uki Yamashita, Yuichi Obata and Takahiro S. Doi

The Journal of Immunology November 15, 2007, 179 (10) 6596-6603; DOI: https://doi.org/10.4049/jimmunol.179.10.6596
Open Access
Molecular Mimics Can Induce Novel Self Peptide-Reactive CD4⁺ T Cell Clonotypes in Autoimmune Disease
Anne M. Ercolini and Stephen D. Miller

The Journal of Immunology November 15, 2007, 179 (10) 6604-6612; DOI: https://doi.org/10.4049/jimmunol.179.10.6604
Open Access
Nitric Oxide Mediates T Cell Cytokine Production and Signal Transduction in Histidine Decarboxylase Knockout Mice
Agnes Koncz, Maria Pasztoi, Mercedesz Mazan, Ferenc Fazakas, Edit Buzas, Andras Falus and Gyorgy Nagy

The Journal of Immunology November 15, 2007, 179 (10) 6613-6619; DOI: https://doi.org/10.4049/jimmunol.179.10.6613
Open Access
Type 1 IFN Mediates Cross-Talk between Innate and Adaptive Immunity That Abrogates Transplantation Tolerance
Thomas B. Thornley, Nancy E. Phillips, Britte C. Beaudette-Zlatanova, Thomas G. Markees, Kapil Bahl, Michael A. Brehm, Leonard D. Shultz, Evelyn A. Kurt-Jones, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini and Dale L. Greiner

The Journal of Immunology November 15, 2007, 179 (10) 6620-6629; DOI: https://doi.org/10.4049/jimmunol.179.10.6620
Open Access
Peripheral NK1.1⁻ NKT Cells Are Mature and Functionally Distinct from Their Thymic Counterparts
Finlay W. McNab, Daniel G. Pellicci, Kenneth Field, Gurdyal Besra, Mark J. Smyth, Dale I. Godfrey and Stuart P. Berzins

The Journal of Immunology November 15, 2007, 179 (10) 6630-6637; DOI: https://doi.org/10.4049/jimmunol.179.10.6630
Open Access
Increased Sequence Diversity Coverage Improves Detection of HIV-Specific T Cell Responses
Nicole Frahm, Daniel E. Kaufmann, Karina Yusim, Mark Muldoon, Can Kesmir, Caitlyn H. Linde, Will Fischer, Todd M. Allen, Bin Li, Ben H. McMahon, Kellie L. Faircloth, Hannah S. Hewitt, Elizabeth W. Mackey, Toshiyuki Miura, Ashok Khatri, Steven Wolinsky, Andrew McMichael, Robert K. Funkhouser, Bruce D. Walker, Christian Brander and Bette T. Korber

The Journal of Immunology November 15, 2007, 179 (10) 6638-6650; DOI: https://doi.org/10.4049/jimmunol.179.10.6638
Open Access
CD8 T Cell Help for Innate Antitumor Immunity
Anil Shanker, Grégory Verdeil, Michel Buferne, Else-Marit Inderberg-Suso, Denis Puthier, Florence Joly, Catherine Nguyen, Lee Leserman, Nathalie Auphan-Anezin and Anne-Marie Schmitt-Verhulst

The Journal of Immunology November 15, 2007, 179 (10) 6651-6662; DOI: https://doi.org/10.4049/jimmunol.179.10.6651
Open Access
Primary Development and Participation in a Foreign Antigen-Driven Immune Response of a Chromatin-Reactive B Cell Clonotype Are Not Influenced by TLR9 or Other MyD88-Dependent TLRs
Francis Coffey, Xiaohe Liu and Tim Manser

The Journal of Immunology November 15, 2007, 179 (10) 6663-6672; DOI: https://doi.org/10.4049/jimmunol.179.10.6663
Open Access
Dual Role of Melanoma Cell Adhesion Molecule (MCAM)/CD146 in Lymphocyte Endothelium Interaction: MCAM/CD146 Promotes Rolling via Microvilli Induction in Lymphocyte and Is an Endothelial Adhesion Receptor
Borhane Guezguez, Pascale Vigneron, Nathalie Lamerant, Claudine Kieda, Thierry Jaffredo and Dominique Dunon

The Journal of Immunology November 15, 2007, 179 (10) 6673-6685; DOI: https://doi.org/10.4049/jimmunol.179.10.6673
Open Access
Anti-CD40 Conditioning Enhances the T_CD8 Response to a Highly Tolerogenic Epitope and Subsequent Immunotherapy of Simian Virus 40 T Antigen-Induced Pancreatic Tumors
Pavel Otahal, Barbara B. Knowles, Satvir S. Tevethia and Todd D. Schell

The Journal of Immunology November 15, 2007, 179 (10) 6686-6695; DOI: https://doi.org/10.4049/jimmunol.179.10.6686
Open Access
Impact of CD40 Ligand, B Cells, and Mast Cells in Peanut-Induced Anaphylactic Responses
Jiangfeng Sun, Katherine Arias, David Alvarez, Ramzi Fattouh, Tina Walker, Susanna Goncharova, Bobae Kim, Susan Waserman, Jennifer Reed, Anthony J. Coyle and Manel Jordana

The Journal of Immunology November 15, 2007, 179 (10) 6696-6703; DOI: https://doi.org/10.4049/jimmunol.179.10.6696
Open Access
Strength of Stimulus and Clonal Competition Impact the Rate of Memory CD8 T Cell Differentiation
Surojit Sarkar, Volker Teichgräber, Vandana Kalia, Antonio Polley, David Masopust, Laurie E. Harrington, Rafi Ahmed and E. John Wherry

The Journal of Immunology November 15, 2007, 179 (10) 6704-6714; DOI: https://doi.org/10.4049/jimmunol.179.10.6704
Open Access
Cell Surface Colony-Stimulating Factor 1 Can Be Cleaved by TNF-α Converting Enzyme or Endocytosed in a Clathrin-Dependent Manner
Keisuke Horiuchi, Takeshi Miyamoto, Hironari Takaishi, Akihiro Hakozaki, Naoto Kosaki, Yoshiteru Miyauchi, Mitsuru Furukawa, Jiro Takito, Hironori Kaneko, Kenichiro Matsuzaki, Hideo Morioka, Carl P. Blobel and Yoshiaki Toyama

The Journal of Immunology November 15, 2007, 179 (10) 6715-6724; DOI: https://doi.org/10.4049/jimmunol.179.10.6715
Open Access
Duration of Antigen Expression In Vivo following DNA Immunization Modifies the Magnitude, Contraction, and Secondary Responses of CD8⁺ T Lymphocytes
Avi-Hai Hovav, Michael W. Panas, Shaila Rahman, Piya Sircar, Geoffrey Gillard, Mark J. Cayabyab and Norman L. Letvin

The Journal of Immunology November 15, 2007, 179 (10) 6725-6733; DOI: https://doi.org/10.4049/jimmunol.179.10.6725
Open Access
Dual Roles of IL-15 in Maintaining IL-7Rα^lowCCR7⁻ Memory CD8⁺ T Cells in Humans via Recovering the Phosphatidylinositol 3-Kinase/AKT Pathway
Hang-Rae Kim, Kyung-A Hwang and Insoo Kang

The Journal of Immunology November 15, 2007, 179 (10) 6734-6740; DOI: https://doi.org/10.4049/jimmunol.179.10.6734
Open Access
Shaping of the Autoreactive Regulatory T Cell Repertoire by Thymic Cortical Positive Selection
Julie Ribot, Geneviève Enault, Sylvie Pilipenko, Anne Huchenq, Maryline Calise, Denis Hudrisier, Paola Romagnoli and Joost P. M. van Meerwijk

The Journal of Immunology November 15, 2007, 179 (10) 6741-6748; DOI: https://doi.org/10.4049/jimmunol.179.10.6741
Open Access
Developmental Exposure to Noninherited Maternal Antigens Induces CD4⁺ T Regulatory Cells: Relevance to Mechanism of Heart Allograft Tolerance
Melanie L. Molitor-Dart, Joachim Andrassy, Jean Kwun, H. Ayhan Kayaoglu, Drew A. Roenneburg, Lynn D. Haynes, Jose R. Torrealba, Joseph L. Bobadilla, Hans W. Sollinger, Stuart J. Knechtle and William J. Burlingham

The Journal of Immunology November 15, 2007, 179 (10) 6749-6761; DOI: https://doi.org/10.4049/jimmunol.179.10.6749
Open Access
Induction of Robust Diabetes Resistance and Prevention of Recurrent Type 1 Diabetes Following Islet Transplantation by Gene Therapy
Chaorui Tian, Mohammed Javeed I. Ansari, Jesus Paez-Cortez, Jessamyn Bagley, Jonathan Godwin, Michela Donnarumma, Mohamed H. Sayegh and John Iacomini

The Journal of Immunology November 15, 2007, 179 (10) 6762-6769; DOI: https://doi.org/10.4049/jimmunol.179.10.6762
Open Access
Sulfated Glycosphingolipid as Mediator of Phagocytosis: SM4s Enhances Apoptotic Cell Clearance and Modulates Macrophage Activity
Zoran V. Popovic, Roger Sandhoff, Tjeerd P. Sijmonsma, Sylvia Kaden, Richard Jennemann, Eva Kiss, Edgar Tone, Frank Autschbach, Nick Platt, Ernst Malle and Hermann-Josef Gröne

The Journal of Immunology November 15, 2007, 179 (10) 6770-6782; DOI: https://doi.org/10.4049/jimmunol.179.10.6770
Open Access
Localization and Differential Expression of Activation-Induced Cytidine Deaminase in the Amphibian Xenopus upon Antigen Stimulation and during Early Development
Shauna Marr, Heidi Morales, Andrea Bottaro, Michelle Cooper, Martin Flajnik and Jacques Robert

The Journal of Immunology November 15, 2007, 179 (10) 6783-6789; DOI: https://doi.org/10.4049/jimmunol.179.10.6783
Open Access
IL-6 Contributes to the Expression of RAGs in Human Mature B Cells
Sophie Hillion, Maryvonne Dueymes, Pierre Youinou and Christophe Jamin

The Journal of Immunology November 15, 2007, 179 (10) 6790-6798; DOI: https://doi.org/10.4049/jimmunol.179.10.6790
Open Access
Developmental Stage-Dependent Collaboration between the TNF Receptor-Associated Factor 6 and Lymphotoxin Pathways for B Cell Follicle Organization in Secondary Lymphoid Organs
Junwen Qin, Hiroyasu Konno, Daisuke Ohshima, Hiromi Yanai, Hidehiko Motegi, Yusuke Shimo, Fumiko Hirota, Mitsuru Matsumoto, Satoshi Takaki, Jun-ichiro Inoue and Taishin Akiyama

The Journal of Immunology November 15, 2007, 179 (10) 6799-6807; DOI: https://doi.org/10.4049/jimmunol.179.10.6799
Open Access
Transcriptional Profiling of Antigen-Dependent Murine B Cell Differentiation and Memory Formation
Deepta Bhattacharya, Ming T. Cheah, Christopher B. Franco, Naoki Hosen, Christopher L. Pin, William C. Sha and Irving L. Weissman

The Journal of Immunology November 15, 2007, 179 (10) 6808-6819; DOI: https://doi.org/10.4049/jimmunol.179.10.6808
Open Access
PTEN Down-Regulates IL-17 Expression in a Murine Model of Toluene Diisocyanate-Induced Airway Disease
So Ri Kim, Kyung Sun Lee, Seoung Ju Park, Kyung Hoon Min, Ka Young Lee, Yeong Hun Choe, Young Rae Lee, Jong Suk Kim, Soo Jong Hong and Yong Chul Lee

The Journal of Immunology November 15, 2007, 179 (10) 6820-6829; DOI: https://doi.org/10.4049/jimmunol.179.10.6820
Open Access
Langerhans Cells Are Required for Efficient Presentation of Topically Applied Hapten to T Cells
Clare L. Bennett, Madelon Noordegraaf, Cerithsa A. E. Martina and Björn E. Clausen

The Journal of Immunology November 15, 2007, 179 (10) 6830-6835; DOI: https://doi.org/10.4049/jimmunol.179.10.6830
Open Access
Raf Signaling but not the ERK Effector SAP-1 Is Required for Regulatory T Cell Development
Jane E. Willoughby, Patrick S. Costello, Robert H. Nicolas, Nicholas J. Robinson, Gordon Stamp, Fiona Powrie and Richard Treisman

The Journal of Immunology November 15, 2007, 179 (10) 6836-6844; DOI: https://doi.org/10.4049/jimmunol.179.10.6836

MOLECULAR AND STRUCTURAL IMMUNOLOGY

Open Access
Early and Dynamic Polarization of T Cell Membrane Rafts and Constituents Prior to TCR Stop Signals
Jeffrey S. Van Komen, Sudha Mishra, Jennifer Byrum, Gurunadh R. Chichili, Jane C. Yaciuk, A. Darise Farris and William Rodgers

The Journal of Immunology November 15, 2007, 179 (10) 6845-6855; DOI: https://doi.org/10.4049/jimmunol.179.10.6845
Open Access
Distinctive Interactions at Multiple Site 2 Subsites by Allele-Specific Rat and Mouse Ly49 Determine Functional Binding and Class I MHC Specificity
Kerry J. Lavender, Heidi H. Chau and Kevin P. Kane

The Journal of Immunology November 15, 2007, 179 (10) 6856-6866; DOI: https://doi.org/10.4049/jimmunol.179.10.6856
Open Access
Spatiotemporal Mobilization of Toll/IL-1 Receptor Domain-Containing Adaptor Molecule-1 in Response to dsRNA
Kenji Funami, Miwa Sasai, Yusuke Ohba, Hiroyuki Oshiumi, Tsukasa Seya and Misako Matsumoto

The Journal of Immunology November 15, 2007, 179 (10) 6867-6872; DOI: https://doi.org/10.4049/jimmunol.179.10.6867
Open Access
JunB Is Required for IgE-Mediated Degranulation and Cytokine Release of Mast Cells
Björn Textor, Alexander H. Licht, Jan P. Tuckermann, Rolf Jessberger, Ehud Razin, Peter Angel, Marina Schorpp-Kistner and Bettina Hartenstein

The Journal of Immunology November 15, 2007, 179 (10) 6873-6880; DOI: https://doi.org/10.4049/jimmunol.179.10.6873
Open Access
Targeting IFN-α to B Cell Lymphoma by a Tumor-Specific Antibody Elicits Potent Antitumor Activities
Tzu-Hsuan Huang, Koteswara R. Chintalacharuvu and Sherie L. Morrison

The Journal of Immunology November 15, 2007, 179 (10) 6881-6888; DOI: https://doi.org/10.4049/jimmunol.179.10.6881

HOST DEFENSE

Open Access
Trans-Sialidase Recombinant Protein Mixed with CpG Motif-Containing Oligodeoxynucleotide Induces Protective Mucosal and Systemic Trypanosoma cruzi Immunity Involving CD8⁺ CTL and B Cell-Mediated Cross-Priming
Daniel F. Hoft, Christopher S. Eickhoff, Olivia K. Giddings, José R. C. Vasconcelos and Maurício M. Rodrigues

The Journal of Immunology November 15, 2007, 179 (10) 6889-6900; DOI: https://doi.org/10.4049/jimmunol.179.10.6889
Open Access
LIGHT Is Critical for IL-12 Production by Dendritic Cells, Optimal CD4⁺ Th1 Cell Response, and Resistance to Leishmania major
Guilian Xu, Dong Liu, Ifeoma Okwor, Yang Wang, Heinrich Korner, Sam K. P. Kung, Yang-Xin Fu and Jude E. Uzonna

The Journal of Immunology November 15, 2007, 179 (10) 6901-6909; DOI: https://doi.org/10.4049/jimmunol.179.10.6901
Open Access
CCAAT/Enhancer-Binding Protein β and δ Binding to CIITA Promoters Is Associated with the Inhibition of CIITA Expression in Response to Mycobacterium tuberculosis 19-kDa Lipoprotein
Meghan E. Pennini, Yi Liu, Jianqi Yang, Colleen M. Croniger, W. Henry Boom and Clifford V. Harding

The Journal of Immunology November 15, 2007, 179 (10) 6910-6918; DOI: https://doi.org/10.4049/jimmunol.179.10.6910
Open Access
Progression of Pulmonary Tuberculosis and Efficiency of Bacillus Calmette-Guérin Vaccination Are Genetically Controlled via a Common sst1-Mediated Mechanism of Innate Immunity
Bo-Shiun Yan, Alexander V. Pichugin, Ousman Jobe, Laura Helming, Evgeniy B. Eruslanov, José A. Gutiérrez-Pabello, Mauricio Rojas, Yuriy V. Shebzukhov, Lester Kobzik and Igor Kramnik

The Journal of Immunology November 15, 2007, 179 (10) 6919-6932; DOI: https://doi.org/10.4049/jimmunol.179.10.6919
Open Access
Inflammasome-Mediated Production of IL-1β Is Required for Neutrophil Recruitment against Staphylococcus aureus In Vivo
Lloyd S. Miller, Eric M. Pietras, Lawrence H. Uricchio, Kathleen Hirano, Shyam Rao, Heping Lin, Ryan M. O’Connell, Yoichiro Iwakura, Ambrose L. Cheung, Genhong Cheng and Robert L. Modlin

The Journal of Immunology November 15, 2007, 179 (10) 6933-6942; DOI: https://doi.org/10.4049/jimmunol.179.10.6933
Open Access
Noduler, A Novel Immune Up-Regulated Protein Mediates Nodulation Response in Insects
Archana S. Gandhe, Serene H. John and Javaregowda Nagaraju

The Journal of Immunology November 15, 2007, 179 (10) 6943-6951; DOI: https://doi.org/10.4049/jimmunol.179.10.6943
Open Access
The Aryl Hydrocarbon Receptor Is Required for Optimal Resistance to Listeria monocytogenes Infection in Mice
Lewis Zhichang Shi, Nancy G. Faith, Yumi Nakayama, Makulasiddappa Suresh, Howard Steinberg and Charles J. Czuprynski

The Journal of Immunology November 15, 2007, 179 (10) 6952-6962; DOI: https://doi.org/10.4049/jimmunol.179.10.6952
Open Access
Impaired Macrophage Function Underscores Susceptibility to Salmonella in Mice Lacking Irgm1 (LRG-47)
Stanley C. Henry, Xiaojou Daniell, Maanasa Indaram, John F. Whitesides, Gregory D. Sempowski, David Howell, Tim Oliver and Gregory A. Taylor

The Journal of Immunology November 15, 2007, 179 (10) 6963-6972; DOI: https://doi.org/10.4049/jimmunol.179.10.6963
Open Access
HIV Impairs TNF-α Mediated Macrophage Apoptotic Response to Mycobacterium tuberculosis
Naimish R. Patel, Jinping Zhu, Souvenir D. Tachado, Jianmin Zhang, Zhi Wan, Jussi Saukkonen and Henry Koziel

The Journal of Immunology November 15, 2007, 179 (10) 6973-6980; DOI: https://doi.org/10.4049/jimmunol.179.10.6973
Open Access
Altered Inflammatory Responses in TLR5-Deficient Mice Infected with Legionella pneumophila
Thomas R. Hawn, William R. Berrington, Ian A. Smith, Satoshi Uematsu, Shizuo Akira, Alan Aderem, Kelly D. Smith and Shawn J. Skerrett

The Journal of Immunology November 15, 2007, 179 (10) 6981-6987; DOI: https://doi.org/10.4049/jimmunol.179.10.6981

INFLAMMATION

Open Access
Differential Expression of Inflammatory and Fibrogenic Genes and Their Regulation by NF-κB Inhibition in a Mouse Model of Chronic Colitis
Feng Wu and Shukti Chakravarti

The Journal of Immunology November 15, 2007, 179 (10) 6988-7000; DOI: https://doi.org/10.4049/jimmunol.179.10.6988
Open Access
Src Tyrosine Kinases Mediate Activations of NF-κB and Integrin Signal during Lipopolysaccharide-Induced Acute Lung Injury
Hui S. Lee, Changsuk Moon, Hye W. Lee, Eun-Mi Park, Min-Sun Cho and Jihee L. Kang

The Journal of Immunology November 15, 2007, 179 (10) 7001-7011; DOI: https://doi.org/10.4049/jimmunol.179.10.7001
Open Access
Resistin-Like Molecule β (RELMβ/FIZZ2) Is Highly Expressed in the Ileum of SAMP1/YitFc Mice and Is Associated with Initiation of Ileitis
Sean L. Barnes, Alda Vidrich, Mei-Lun Wang, Gary D. Wu, Fabio Cominelli, Jesus Rivera-Nieves, Giorgos Bamias and Steven M. Cohn

The Journal of Immunology November 15, 2007, 179 (10) 7012-7020; DOI: https://doi.org/10.4049/jimmunol.179.10.7012
Open Access
Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo
Hatice Hasturk, Alpdogan Kantarci, Emilie Goguet-Surmenian, Amanda Blackwood, Chris Andry, Charles N. Serhan and Thomas E. Van Dyke

The Journal of Immunology November 15, 2007, 179 (10) 7021-7029; DOI: https://doi.org/10.4049/jimmunol.179.10.7021
Open Access
Inhibition of NF-κB Activation Reduces the Tissue Effects of Transgenic IL-13
Svetlana P. Chapoval, Amal Al-Garawi, Jose M. Lora, Ian Strickland, Bing Ma, Patty J. Lee, Robert J. Homer, Sankar Ghosh, Anthony J. Coyle and Jack A. Elias

The Journal of Immunology November 15, 2007, 179 (10) 7030-7041; DOI: https://doi.org/10.4049/jimmunol.179.10.7030
Open Access
TNF Pretreatment Interferes with Mitochondrial Apoptosis in the Mouse Liver by A20-Mediated Down-Regulation of Bax
Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel and Gisa Tiegs

The Journal of Immunology November 15, 2007, 179 (10) 7042-7049; DOI: https://doi.org/10.4049/jimmunol.179.10.7042
Open Access
Resolution of Der p1-Induced Allergic Airway Inflammation Is Dependent on CD4⁺CD25⁺Foxp3⁺ Regulatory Cells
Melanie D. Leech, Robert A. Benson, Annick deVries, Paul M. Fitch and Sarah E. M. Howie

The Journal of Immunology November 15, 2007, 179 (10) 7050-7058; DOI: https://doi.org/10.4049/jimmunol.179.10.7050
Open Access
FcεRI- and Fcγ Receptor-Mediated Production of Reactive Oxygen Species by Mast Cells Is Lipoxygenase- and Cyclooxygenase-Dependent and NADPH Oxidase-Independent
Emily J. Swindle, John W. Coleman, Frank R. DeLeo and Dean D. Metcalfe

The Journal of Immunology November 15, 2007, 179 (10) 7059-7071; DOI: https://doi.org/10.4049/jimmunol.179.10.7059
Open Access
Catalytically Inactive Cyclooxygenase 2 and Absence of Prostaglandin E₂ Biosynthesis in Murine Peritoneal Macrophages following In Vivo Phagocytosis of Heat-Killed Mycobacterium bovis Bacillus Calmette-Guérin
Makiko Yamashita, Tsutomu Shinohara, Shoutaro Tsuji, Quentin N. Myrvik, Akihito Nishiyama, Ruth Ann Henriksen and Yoshimi Shibata

The Journal of Immunology November 15, 2007, 179 (10) 7072-7078; DOI: https://doi.org/10.4049/jimmunol.179.10.7072
Open Access
Involvement of Vitronectin in Lipopolysaccaride-Induced Acute Lung Injury
Yuko Tsuruta, Young-Jun Park, Gene P. Siegal, Gang Liu and Edward Abraham

The Journal of Immunology November 15, 2007, 179 (10) 7079-7086; DOI: https://doi.org/10.4049/jimmunol.179.10.7079
Open Access
Overexpression of Bcl_XL in B Cells Promotes Th1 Response and Exacerbates Collagen-Induced Arthritis
Biao Zheng, Ekaterina Marinova, Kirsten Switzer, Daniel Wansley, Hongxia He, Roy Bheekha-Escura, Timothy W. Behrens and Shuhua Han

The Journal of Immunology November 15, 2007, 179 (10) 7087-7092; DOI: https://doi.org/10.4049/jimmunol.179.10.7087
Open Access
Mast Cells and Basophils Are Selectively Activated In Vitro and In Vivo through CD200R3 in an IgE-Independent Manner
Toshiyuki Kojima, Kazushige Obata, Kaori Mukai, Shingo Sato, Toshiyuki Takai, Yoshiyuki Minegishi and Hajime Karasuyama

The Journal of Immunology November 15, 2007, 179 (10) 7093-7100; DOI: https://doi.org/10.4049/jimmunol.179.10.7093
Open Access
MAPK p38 Regulates Transcriptional Activity of NF-κB in Primary Human Astrocytes via Acetylation of p65
Ramendra N. Saha, Malabendu Jana and Kalipada Pahan

The Journal of Immunology November 15, 2007, 179 (10) 7101-7109; DOI: https://doi.org/10.4049/jimmunol.179.10.7101
Open Access
Induction of IRAK-M Is Associated with Lipopolysaccharide Tolerance in a Human Endotoxemia Model
Cornelis van ‘t Veer, Petra S. van den Pangaart, Marieke A. D. van Zoelen, Martijn de Kruif, Rakesh S. Birjmohun, Eric S. Stroes, Alex F. de Vos and Tom van der Poll

The Journal of Immunology November 15, 2007, 179 (10) 7110-7120; DOI: https://doi.org/10.4049/jimmunol.179.10.7110
Open Access
Apigenin Blocks Lipopolysaccharide-Induced Lethality In Vivo and Proinflammatory Cytokines Expression by Inactivating NF-κB through the Suppression of p65 Phosphorylation
Courtney Nicholas, Sanjay Batra, Melissa A. Vargo, Oliver H. Voss, Mikhail A. Gavrilin, Mark D. Wewers, Denis C. Guttridge, Erich Grotewold and Andrea I. Doseff

The Journal of Immunology November 15, 2007, 179 (10) 7121-7127; DOI: https://doi.org/10.4049/jimmunol.179.10.7121
Open Access
IL-17B and IL-17C Are Associated with TNF-α Production and Contribute to the Exacerbation of Inflammatory Arthritis
Yumi Yamaguchi, Keishi Fujio, Hirofumi Shoda, Akiko Okamoto, Nelson H. Tsuno, Koki Takahashi and Kazuhiko Yamamoto

The Journal of Immunology November 15, 2007, 179 (10) 7128-7136; DOI: https://doi.org/10.4049/jimmunol.179.10.7128

CLINICAL IMMUNOLOGY

Open Access
Extracellular Branched-Chain Amino Acids, Especially Valine, Regulate Maturation and Function of Monocyte-Derived Dendritic Cells
Eiji Kakazu, Noriatsu Kanno, Yoshiyuki Ueno and Tooru Shimosegawa

The Journal of Immunology November 15, 2007, 179 (10) 7137-7146; DOI: https://doi.org/10.4049/jimmunol.179.10.7137
Open Access
Jak2 Dampens the Induction by IL-1β of Prostaglandin Endoperoxide H Synthase 2 Expression in Human Orbital Fibroblasts: Evidence for Divergent Influence on the Prostaglandin E₂ Biosynthetic Pathway
Rui Han, Beiling Chen and Terry J. Smith

The Journal of Immunology November 15, 2007, 179 (10) 7147-7156; DOI: https://doi.org/10.4049/jimmunol.179.10.7147
Open Access
IL-21 Administration into the Nostril Alleviates Murine Allergic Rhinitis
Yayoi Hiromura, Tsunao Kishida, Hiroshi Nakano, Takemitsu Hama, Jiro Imanishi, Yasuo Hisa and Osam Mazda

The Journal of Immunology November 15, 2007, 179 (10) 7157-7165; DOI: https://doi.org/10.4049/jimmunol.179.10.7157
Open Access
Elevated Urinary VCAM-1, P-Selectin, Soluble TNF Receptor-1, and CXC Chemokine Ligand 16 in Multiple Murine Lupus Strains and Human Lupus Nephritis
Tianfu Wu, Chun Xie, Hong W. Wang, Xin J. Zhou, Noa Schwartz, Sergio Calixto, Meggan Mackay, Cynthia Aranow, Chaim Putterman and Chandra Mohan

The Journal of Immunology November 15, 2007, 179 (10) 7166-7175; DOI: https://doi.org/10.4049/jimmunol.179.10.7166
Open Access
IFN-γ Produced by Human Papilloma Virus-18 E6-Specific CD4⁺ T Cells Predicts the Clinical Outcome after Surgery in Patients with High-Grade Cervical Lesions
Samantha Seresini, Massimo Origoni, Flavia Lillo, Luigi Caputo, Anna Maria Paganoni, Simone Vantini, Renato Longhi, Gianluca Taccagni, Augusto Ferrari, Claudio Doglioni, Piercesare Secchi and Maria Pia Protti

The Journal of Immunology November 15, 2007, 179 (10) 7176-7183; DOI: https://doi.org/10.4049/jimmunol.179.10.7176

CORRECTIONS

Open Access
Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer.
M. J. Anderson, K. Shafer-Weaver, N. M. Greenberg and A. A. Hurwitz

The Journal of Immunology November 15, 2007, 179 (10) 7184; DOI: https://doi.org/10.4049/jimmunol.179.10.7184
Open Access
C57BL/6 mice genetically deficient in IL-12/IL-23 and IFN-γ are susceptible to experimental autoimmune myasthenia gravis, suggesting a pathogenic role of non-Th1 cells.
W. Wang, M. Milani, N. Ostlie, D. Okita, R. K. Agarwal, R. Caspi and B. M. Conti-Fine

The Journal of Immunology November 15, 2007, 179 (10) 7184; DOI: https://doi.org/10.4049/jimmunol.179.10.7184-a
Open Access
CCL19 and CXL13 synergistically regulate interaction between B cell acute lymphocytic leukemia CD23⁺CD25⁺ B cells and CD8⁺ T cells.
X. Wang, H. Yuling, J. Yanping, T. Xinti, Y. Yaofang, Y. Feng, X. Ruijin, W. Li, C. Lang and L. Jingyi

The Journal of Immunology November 15, 2007, 179 (10) 7184; DOI: https://doi.org/10.4049/jimmunol.179.10.7184-b
Open Access
Complement-dependent enhancement of CD8⁺ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice.
C. Fang, T. Miwa, H. Shen and W.-C. Song

The Journal of Immunology November 15, 2007, 179 (10) 7185; DOI: https://doi.org/10.4049/jimmunol.179.10.7185
Open Access
Cutting edge: a critical role of nitrogen oxide in preventing inflammation upon apoptotic cell clearance.
T. Shibata, K. Nagata and Y. Kobayashi

The Journal of Immunology November 15, 2007, 179 (10) 7185; DOI: https://doi.org/10.4049/jimmunol.179.10.7185-a
Open Access
Lymphotoxin αβ2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice.
G. Xu, D. Liu, Y. Fan, X. Yang, H. Korner, Y.-X. Fu and J. E. Uzonna

The Journal of Immunology November 15, 2007, 179 (10) 7185; DOI: https://doi.org/10.4049/jimmunol.179.10.7185-b

IN THIS ISSUE

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IN THIS ISSUE

J Immunol November 15, 2007, 179 (10) 6377-6378; DOI: https://doi.org/10.4049/jimmunol.179.10.6377

CUTTING EDGE

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Cutting Edge: Identification of a Pre-Ligand Assembly Domain (PLAD) and Ligand Binding Site in the IL-17 Receptor
Jill M. Kramer, Walter Hanel, Fang Shen, Nilgun Isik, James P. Malone, Amarnath Maitra, Wade Sigurdson, David Swart, Joel Tocker, Tian Jin and Sarah L. Gaffen

J Immunol November 15, 2007, 179 (10) 6379-6383; DOI: https://doi.org/10.4049/jimmunol.179.10.6379
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Cutting Edge: Rac GTPases Sensitize Activated T Cells to Die via Fas
Madhu Ramaswamy, Celine Dumont, Anthony C. Cruz, Jagan R. Muppidi, Timothy S. Gomez, Daniel D. Billadeau, Victor L. J. Tybulewicz and Richard M. Siegel

J Immunol November 15, 2007, 179 (10) 6384-6388; DOI: https://doi.org/10.4049/jimmunol.179.10.6384

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Tolerance Induction in Presensitized Bone Marrow Recipients by Veto CTLs: Effective Deletion of Host Anti-Donor Memory Effector Cells
Shlomit Reich-Zeliger, Esther Bachar-Lustig, Avichai Bar-Ilan and Yair Reisner

J Immunol November 15, 2007, 179 (10) 6389-6394; DOI: https://doi.org/10.4049/jimmunol.179.10.6389
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Differentiation and Ig-Allele Switch in Cell Line WEHI-231
Freia J. X. Spillmann, Gabriele Beck-Engeser and Matthias Wabl

J Immunol November 15, 2007, 179 (10) 6395-6402; DOI: https://doi.org/10.4049/jimmunol.179.10.6395
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Age-Related Defects in Moesin/Ezrin Cytoskeletal Signals in Mouse CD4 T Cells
Gonzalo G. Garcia, Amir A. Sadighi Akha and Richard A. Miller

J Immunol November 15, 2007, 179 (10) 6403-6409; DOI: https://doi.org/10.4049/jimmunol.179.10.6403
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Temporal and Spatial Changes of Histone 3 K4 Dimethylation at the IFN-γ Gene during Th1 and Th2 Cell Differentiation
Heli K. Hamalainen-Laanaya, James J. Kobie, Chawnshang Chang and Wei-ping Zeng

J Immunol November 15, 2007, 179 (10) 6410-6415; DOI: https://doi.org/10.4049/jimmunol.179.10.6410
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The Activating Immunoreceptor NKG2D and Its Ligands Are Involved in Allograft Transplant Rejection
Jim Kim, Catherine K. Chang, Tracy Hayden, Feng-Chun Liu, Jonathan Benjamin, Jessica A. Hamerman, Lewis L. Lanier and Sang-Mo Kang

J Immunol November 15, 2007, 179 (10) 6416-6420; DOI: https://doi.org/10.4049/jimmunol.179.10.6416
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Augmentation of Antigen-Presenting and Th1-Promoting Functions of Dendritic Cells by WSX-1(IL-27R) Deficiency
Sen Wang, Yoshiyuki Miyazaki, Yukari Shinozaki and Hiroki Yoshida

J Immunol November 15, 2007, 179 (10) 6421-6428; DOI: https://doi.org/10.4049/jimmunol.179.10.6421
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Differences in Expression, Affinity, and Function of Soluble (s)IL-4Rα and sIL-13Rα2 Suggest Opposite Effects on Allergic Responses
Marat Khodoun, Christina Lewis, Jun-Qi Yang, Tatyana Orekov, Crystal Potter, Thomas Wynn, Margaret Mentink-Kane, Gurjit K. Khurana Hershey, Marsha Wills-Karp and Fred D. Finkelman

J Immunol November 15, 2007, 179 (10) 6429-6438; DOI: https://doi.org/10.4049/jimmunol.179.10.6429
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Preferential Migration of T Regulatory Cells Induced by IL-16
Caroline McFadden, Ross Morgan, Shilpa Rahangdale, Daniel Green, Hisato Yamasaki, David Center and William Cruikshank

J Immunol November 15, 2007, 179 (10) 6439-6445; DOI: https://doi.org/10.4049/jimmunol.179.10.6439
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IL-4 Suppresses Dendritic Cell Response to Type I Interferons
Uma Sriram, Chhanda Biswas, Edward M. Behrens, Joudy-Ann Dinnall, Debra K. Shivers, Marc Monestier, Yair Argon and Stefania Gallucci

J Immunol November 15, 2007, 179 (10) 6446-6455; DOI: https://doi.org/10.4049/jimmunol.179.10.6446
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The Requirement of Reversible Cysteine Sulfenic Acid Formation for T Cell Activation and Function
Ryan D. Michalek, Kimberly J. Nelson, Beth C. Holbrook, John S. Yi, Daya Stridiron, Larry W. Daniel, Jacquelyn S. Fetrow, S. Bruce King, Leslie B. Poole and Jason M. Grayson

J Immunol November 15, 2007, 179 (10) 6456-6467; DOI: https://doi.org/10.4049/jimmunol.179.10.6456
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Select Plant Tannins Induce IL-2Rα Up-Regulation and Augment Cell Division in γδ T Cells
Jeff Holderness, Larissa Jackiw, Emily Kimmel, Hannah Kerns, Miranda Radke, Jodi F. Hedges, Charles Petrie, Patrick McCurley, Pati M. Glee, Aiyappa Palecanda and Mark A. Jutila

J Immunol November 15, 2007, 179 (10) 6468-6478; DOI: https://doi.org/10.4049/jimmunol.179.10.6468
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Leflunomide Inhibits PDK1/Akt Pathway and Induces Apoptosis of Human Mast Cells
Norifumi Sawamukai, Kazuyoshi Saito, Kunihiro Yamaoka, Shingo Nakayamada, Chisei Ra and Yoshiya Tanaka

J Immunol November 15, 2007, 179 (10) 6479-6484; DOI: https://doi.org/10.4049/jimmunol.179.10.6479
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CCR7 Signaling Inhibits T Cell Proliferation
Ekkehard Ziegler, Martin Oberbarnscheidt, Silvia Bulfone-Paus, Reinhold Förster, Ulrich Kunzendorf and Stefan Krautwald

J Immunol November 15, 2007, 179 (10) 6485-6493; DOI: https://doi.org/10.4049/jimmunol.179.10.6485
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Memory CD8⁺ T Cells Require CD28 Costimulation
Annie B. Borowski, Alina C. Boesteanu, Yvonne M. Mueller, Caterina Carafides, David J. Topham, John D. Altman, Stephen R. Jennings and Peter D. Katsikis

J Immunol November 15, 2007, 179 (10) 6494-6503; DOI: https://doi.org/10.4049/jimmunol.179.10.6494
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Requirement for Both JAK-Mediated PI3K Signaling and ACT1/TRAF6/TAK1-Dependent NF-κB Activation by IL-17A in Enhancing Cytokine Expression in Human Airway Epithelial Cells
Fei Huang, Cheng-Yuan Kao, Shinichiro Wachi, Philip Thai, Jisu Ryu and Reen Wu

J Immunol November 15, 2007, 179 (10) 6504-6513; DOI: https://doi.org/10.4049/jimmunol.179.10.6504
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CD4⁺CD28^null T Cells in Autoimmune Disease: Pathogenic Features and Decreased Susceptibility to Immunoregulation
Marielle Thewissen, Veerle Somers, Niels Hellings, Judith Fraussen, Jan Damoiseaux and Piet Stinissen

J Immunol November 15, 2007, 179 (10) 6514-6523; DOI: https://doi.org/10.4049/jimmunol.179.10.6514
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The Lipopolysaccharide Adjuvant Effect on T Cells Relies on Nonoverlapping Contributions from the MyD88 Pathway and CD11c⁺ Cells
Jeremy P. McAleer, David J. Zammit, Leo Lefrançois, Robert J. Rossi and Anthony T. Vella

J Immunol November 15, 2007, 179 (10) 6524-6535; DOI: https://doi.org/10.4049/jimmunol.179.10.6524
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IL-1α and IL-1β Are Endogenous Mediators Linking Cell Injury to the Adaptive Alloimmune Response
Deepak A. Rao, Kevin J. Tracey and Jordan S. Pober

J Immunol November 15, 2007, 179 (10) 6536-6546; DOI: https://doi.org/10.4049/jimmunol.179.10.6536
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Naive and Memory T Cells Induce Different Types of Graft-versus-Host Disease
Suparna Dutt, Diane Tseng, Joerg Ermann, Tracy I. George, Yin Ping Liu, Corrine R. Davis, C. Garrison Fathman and Samuel Strober

J Immunol November 15, 2007, 179 (10) 6547-6554; DOI: https://doi.org/10.4049/jimmunol.179.10.6547
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Spontaneous Class Switch Recombination in B Cell Lymphopoiesis Generates Aberrant Switch Junctions and Is Increased after VDJ Rearrangement
Efrat Edry, Sergei B. Koralov, Klaus Rajewsky and Doron Melamed

J Immunol November 15, 2007, 179 (10) 6555-6560; DOI: https://doi.org/10.4049/jimmunol.179.10.6555
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Intrahepatic Lymphocyte Expression of Dipeptidyl Peptidase I-Processed Granzyme B and Perforin Induces Hepatocyte Expression of Serine Proteinase Inhibitor 6 (Serpinb9/SPI-6)
Heather W. Stout-Delgado, Yonas Getachew, Bonnie C. Miller and Dwain L. Thiele

J Immunol November 15, 2007, 179 (10) 6561-6567; DOI: https://doi.org/10.4049/jimmunol.179.10.6561
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The Bw Cells, a Novel B Cell Population Conserved in the Whole Genus Mus
Aude Thiriot, Anne-Marie Drapier, Paulo Vieira, Catherine Fitting, Jean-Marc Cavaillon, Pierre-André Cazenave and Dominique Rueff-Juy

J Immunol November 15, 2007, 179 (10) 6568-6578; DOI: https://doi.org/10.4049/jimmunol.179.10.6568
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Donor Bone Marrow Type II (Non-Vα14Jα18 CD1d-Restricted) NKT Cells Suppress Graft-Versus-Host Disease by Producing IFN-γ and IL-4
Ji Hyung Kim, Eun Young Choi and Doo Hyun Chung

J Immunol November 15, 2007, 179 (10) 6579-6587; DOI: https://doi.org/10.4049/jimmunol.179.10.6579
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Secretory Leukoprotease Inhibitor in Mucosal Lymph Node Dendritic Cells Regulates the Threshold for Mucosal Tolerance
Janneke N. Samsom, Arnold P. J. van der Marel, Lisette A. van Berkel, Joop M. L. M. van Helvoort, Ytje Simons-Oosterhuis, Wendy Jansen, Mascha Greuter, Rob L. H. Nelissen, Cees M. L. Meeuwisse, Edward E. S. Nieuwenhuis, Reina E. Mebius and Georg Kraal

J Immunol November 15, 2007, 179 (10) 6588-6595; DOI: https://doi.org/10.4049/jimmunol.179.10.6588
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A Proximal κB Site in the IL-23 p19 Promoter Is Responsible for RelA- and c-Rel-Dependent Transcription
Setsuko Mise-Omata, Etsushi Kuroda, Junko Niikura, Uki Yamashita, Yuichi Obata and Takahiro S. Doi

J Immunol November 15, 2007, 179 (10) 6596-6603; DOI: https://doi.org/10.4049/jimmunol.179.10.6596
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Molecular Mimics Can Induce Novel Self Peptide-Reactive CD4⁺ T Cell Clonotypes in Autoimmune Disease
Anne M. Ercolini and Stephen D. Miller

J Immunol November 15, 2007, 179 (10) 6604-6612; DOI: https://doi.org/10.4049/jimmunol.179.10.6604
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Nitric Oxide Mediates T Cell Cytokine Production and Signal Transduction in Histidine Decarboxylase Knockout Mice
Agnes Koncz, Maria Pasztoi, Mercedesz Mazan, Ferenc Fazakas, Edit Buzas, Andras Falus and Gyorgy Nagy

J Immunol November 15, 2007, 179 (10) 6613-6619; DOI: https://doi.org/10.4049/jimmunol.179.10.6613
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Type 1 IFN Mediates Cross-Talk between Innate and Adaptive Immunity That Abrogates Transplantation Tolerance
Thomas B. Thornley, Nancy E. Phillips, Britte C. Beaudette-Zlatanova, Thomas G. Markees, Kapil Bahl, Michael A. Brehm, Leonard D. Shultz, Evelyn A. Kurt-Jones, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini and Dale L. Greiner

J Immunol November 15, 2007, 179 (10) 6620-6629; DOI: https://doi.org/10.4049/jimmunol.179.10.6620
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Peripheral NK1.1⁻ NKT Cells Are Mature and Functionally Distinct from Their Thymic Counterparts
Finlay W. McNab, Daniel G. Pellicci, Kenneth Field, Gurdyal Besra, Mark J. Smyth, Dale I. Godfrey and Stuart P. Berzins

J Immunol November 15, 2007, 179 (10) 6630-6637; DOI: https://doi.org/10.4049/jimmunol.179.10.6630
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Increased Sequence Diversity Coverage Improves Detection of HIV-Specific T Cell Responses
Nicole Frahm, Daniel E. Kaufmann, Karina Yusim, Mark Muldoon, Can Kesmir, Caitlyn H. Linde, Will Fischer, Todd M. Allen, Bin Li, Ben H. McMahon, Kellie L. Faircloth, Hannah S. Hewitt, Elizabeth W. Mackey, Toshiyuki Miura, Ashok Khatri, Steven Wolinsky, Andrew McMichael, Robert K. Funkhouser, Bruce D. Walker, Christian Brander and Bette T. Korber

J Immunol November 15, 2007, 179 (10) 6638-6650; DOI: https://doi.org/10.4049/jimmunol.179.10.6638
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CD8 T Cell Help for Innate Antitumor Immunity
Anil Shanker, Grégory Verdeil, Michel Buferne, Else-Marit Inderberg-Suso, Denis Puthier, Florence Joly, Catherine Nguyen, Lee Leserman, Nathalie Auphan-Anezin and Anne-Marie Schmitt-Verhulst

J Immunol November 15, 2007, 179 (10) 6651-6662; DOI: https://doi.org/10.4049/jimmunol.179.10.6651
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Primary Development and Participation in a Foreign Antigen-Driven Immune Response of a Chromatin-Reactive B Cell Clonotype Are Not Influenced by TLR9 or Other MyD88-Dependent TLRs
Francis Coffey, Xiaohe Liu and Tim Manser

J Immunol November 15, 2007, 179 (10) 6663-6672; DOI: https://doi.org/10.4049/jimmunol.179.10.6663
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Dual Role of Melanoma Cell Adhesion Molecule (MCAM)/CD146 in Lymphocyte Endothelium Interaction: MCAM/CD146 Promotes Rolling via Microvilli Induction in Lymphocyte and Is an Endothelial Adhesion Receptor
Borhane Guezguez, Pascale Vigneron, Nathalie Lamerant, Claudine Kieda, Thierry Jaffredo and Dominique Dunon

J Immunol November 15, 2007, 179 (10) 6673-6685; DOI: https://doi.org/10.4049/jimmunol.179.10.6673
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Anti-CD40 Conditioning Enhances the T_CD8 Response to a Highly Tolerogenic Epitope and Subsequent Immunotherapy of Simian Virus 40 T Antigen-Induced Pancreatic Tumors
Pavel Otahal, Barbara B. Knowles, Satvir S. Tevethia and Todd D. Schell

J Immunol November 15, 2007, 179 (10) 6686-6695; DOI: https://doi.org/10.4049/jimmunol.179.10.6686
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Impact of CD40 Ligand, B Cells, and Mast Cells in Peanut-Induced Anaphylactic Responses
Jiangfeng Sun, Katherine Arias, David Alvarez, Ramzi Fattouh, Tina Walker, Susanna Goncharova, Bobae Kim, Susan Waserman, Jennifer Reed, Anthony J. Coyle and Manel Jordana

J Immunol November 15, 2007, 179 (10) 6696-6703; DOI: https://doi.org/10.4049/jimmunol.179.10.6696
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Strength of Stimulus and Clonal Competition Impact the Rate of Memory CD8 T Cell Differentiation
Surojit Sarkar, Volker Teichgräber, Vandana Kalia, Antonio Polley, David Masopust, Laurie E. Harrington, Rafi Ahmed and E. John Wherry

J Immunol November 15, 2007, 179 (10) 6704-6714; DOI: https://doi.org/10.4049/jimmunol.179.10.6704
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Cell Surface Colony-Stimulating Factor 1 Can Be Cleaved by TNF-α Converting Enzyme or Endocytosed in a Clathrin-Dependent Manner
Keisuke Horiuchi, Takeshi Miyamoto, Hironari Takaishi, Akihiro Hakozaki, Naoto Kosaki, Yoshiteru Miyauchi, Mitsuru Furukawa, Jiro Takito, Hironori Kaneko, Kenichiro Matsuzaki, Hideo Morioka, Carl P. Blobel and Yoshiaki Toyama

J Immunol November 15, 2007, 179 (10) 6715-6724; DOI: https://doi.org/10.4049/jimmunol.179.10.6715
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Duration of Antigen Expression In Vivo following DNA Immunization Modifies the Magnitude, Contraction, and Secondary Responses of CD8⁺ T Lymphocytes
Avi-Hai Hovav, Michael W. Panas, Shaila Rahman, Piya Sircar, Geoffrey Gillard, Mark J. Cayabyab and Norman L. Letvin

J Immunol November 15, 2007, 179 (10) 6725-6733; DOI: https://doi.org/10.4049/jimmunol.179.10.6725
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Dual Roles of IL-15 in Maintaining IL-7Rα^lowCCR7⁻ Memory CD8⁺ T Cells in Humans via Recovering the Phosphatidylinositol 3-Kinase/AKT Pathway
Hang-Rae Kim, Kyung-A Hwang and Insoo Kang

J Immunol November 15, 2007, 179 (10) 6734-6740; DOI: https://doi.org/10.4049/jimmunol.179.10.6734
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Shaping of the Autoreactive Regulatory T Cell Repertoire by Thymic Cortical Positive Selection
Julie Ribot, Geneviève Enault, Sylvie Pilipenko, Anne Huchenq, Maryline Calise, Denis Hudrisier, Paola Romagnoli and Joost P. M. van Meerwijk

J Immunol November 15, 2007, 179 (10) 6741-6748; DOI: https://doi.org/10.4049/jimmunol.179.10.6741
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Developmental Exposure to Noninherited Maternal Antigens Induces CD4⁺ T Regulatory Cells: Relevance to Mechanism of Heart Allograft Tolerance
Melanie L. Molitor-Dart, Joachim Andrassy, Jean Kwun, H. Ayhan Kayaoglu, Drew A. Roenneburg, Lynn D. Haynes, Jose R. Torrealba, Joseph L. Bobadilla, Hans W. Sollinger, Stuart J. Knechtle and William J. Burlingham

J Immunol November 15, 2007, 179 (10) 6749-6761; DOI: https://doi.org/10.4049/jimmunol.179.10.6749
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Induction of Robust Diabetes Resistance and Prevention of Recurrent Type 1 Diabetes Following Islet Transplantation by Gene Therapy
Chaorui Tian, Mohammed Javeed I. Ansari, Jesus Paez-Cortez, Jessamyn Bagley, Jonathan Godwin, Michela Donnarumma, Mohamed H. Sayegh and John Iacomini

J Immunol November 15, 2007, 179 (10) 6762-6769; DOI: https://doi.org/10.4049/jimmunol.179.10.6762
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Sulfated Glycosphingolipid as Mediator of Phagocytosis: SM4s Enhances Apoptotic Cell Clearance and Modulates Macrophage Activity
Zoran V. Popovic, Roger Sandhoff, Tjeerd P. Sijmonsma, Sylvia Kaden, Richard Jennemann, Eva Kiss, Edgar Tone, Frank Autschbach, Nick Platt, Ernst Malle and Hermann-Josef Gröne

J Immunol November 15, 2007, 179 (10) 6770-6782; DOI: https://doi.org/10.4049/jimmunol.179.10.6770
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Localization and Differential Expression of Activation-Induced Cytidine Deaminase in the Amphibian Xenopus upon Antigen Stimulation and during Early Development
Shauna Marr, Heidi Morales, Andrea Bottaro, Michelle Cooper, Martin Flajnik and Jacques Robert

J Immunol November 15, 2007, 179 (10) 6783-6789; DOI: https://doi.org/10.4049/jimmunol.179.10.6783
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IL-6 Contributes to the Expression of RAGs in Human Mature B Cells
Sophie Hillion, Maryvonne Dueymes, Pierre Youinou and Christophe Jamin

J Immunol November 15, 2007, 179 (10) 6790-6798; DOI: https://doi.org/10.4049/jimmunol.179.10.6790
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Developmental Stage-Dependent Collaboration between the TNF Receptor-Associated Factor 6 and Lymphotoxin Pathways for B Cell Follicle Organization in Secondary Lymphoid Organs
Junwen Qin, Hiroyasu Konno, Daisuke Ohshima, Hiromi Yanai, Hidehiko Motegi, Yusuke Shimo, Fumiko Hirota, Mitsuru Matsumoto, Satoshi Takaki, Jun-ichiro Inoue and Taishin Akiyama

J Immunol November 15, 2007, 179 (10) 6799-6807; DOI: https://doi.org/10.4049/jimmunol.179.10.6799
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Transcriptional Profiling of Antigen-Dependent Murine B Cell Differentiation and Memory Formation
Deepta Bhattacharya, Ming T. Cheah, Christopher B. Franco, Naoki Hosen, Christopher L. Pin, William C. Sha and Irving L. Weissman

J Immunol November 15, 2007, 179 (10) 6808-6819; DOI: https://doi.org/10.4049/jimmunol.179.10.6808
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PTEN Down-Regulates IL-17 Expression in a Murine Model of Toluene Diisocyanate-Induced Airway Disease
So Ri Kim, Kyung Sun Lee, Seoung Ju Park, Kyung Hoon Min, Ka Young Lee, Yeong Hun Choe, Young Rae Lee, Jong Suk Kim, Soo Jong Hong and Yong Chul Lee

J Immunol November 15, 2007, 179 (10) 6820-6829; DOI: https://doi.org/10.4049/jimmunol.179.10.6820
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Langerhans Cells Are Required for Efficient Presentation of Topically Applied Hapten to T Cells
Clare L. Bennett, Madelon Noordegraaf, Cerithsa A. E. Martina and Björn E. Clausen

J Immunol November 15, 2007, 179 (10) 6830-6835; DOI: https://doi.org/10.4049/jimmunol.179.10.6830
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Raf Signaling but not the ERK Effector SAP-1 Is Required for Regulatory T Cell Development
Jane E. Willoughby, Patrick S. Costello, Robert H. Nicolas, Nicholas J. Robinson, Gordon Stamp, Fiona Powrie and Richard Treisman

J Immunol November 15, 2007, 179 (10) 6836-6844; DOI: https://doi.org/10.4049/jimmunol.179.10.6836

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Early and Dynamic Polarization of T Cell Membrane Rafts and Constituents Prior to TCR Stop Signals
Jeffrey S. Van Komen, Sudha Mishra, Jennifer Byrum, Gurunadh R. Chichili, Jane C. Yaciuk, A. Darise Farris and William Rodgers

J Immunol November 15, 2007, 179 (10) 6845-6855; DOI: https://doi.org/10.4049/jimmunol.179.10.6845
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Distinctive Interactions at Multiple Site 2 Subsites by Allele-Specific Rat and Mouse Ly49 Determine Functional Binding and Class I MHC Specificity
Kerry J. Lavender, Heidi H. Chau and Kevin P. Kane

J Immunol November 15, 2007, 179 (10) 6856-6866; DOI: https://doi.org/10.4049/jimmunol.179.10.6856
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Spatiotemporal Mobilization of Toll/IL-1 Receptor Domain-Containing Adaptor Molecule-1 in Response to dsRNA
Kenji Funami, Miwa Sasai, Yusuke Ohba, Hiroyuki Oshiumi, Tsukasa Seya and Misako Matsumoto

J Immunol November 15, 2007, 179 (10) 6867-6872; DOI: https://doi.org/10.4049/jimmunol.179.10.6867
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JunB Is Required for IgE-Mediated Degranulation and Cytokine Release of Mast Cells
Björn Textor, Alexander H. Licht, Jan P. Tuckermann, Rolf Jessberger, Ehud Razin, Peter Angel, Marina Schorpp-Kistner and Bettina Hartenstein

J Immunol November 15, 2007, 179 (10) 6873-6880; DOI: https://doi.org/10.4049/jimmunol.179.10.6873
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Targeting IFN-α to B Cell Lymphoma by a Tumor-Specific Antibody Elicits Potent Antitumor Activities
Tzu-Hsuan Huang, Koteswara R. Chintalacharuvu and Sherie L. Morrison

J Immunol November 15, 2007, 179 (10) 6881-6888; DOI: https://doi.org/10.4049/jimmunol.179.10.6881

HOST DEFENSE

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Trans-Sialidase Recombinant Protein Mixed with CpG Motif-Containing Oligodeoxynucleotide Induces Protective Mucosal and Systemic Trypanosoma cruzi Immunity Involving CD8⁺ CTL and B Cell-Mediated Cross-Priming
Daniel F. Hoft, Christopher S. Eickhoff, Olivia K. Giddings, José R. C. Vasconcelos and Maurício M. Rodrigues

J Immunol November 15, 2007, 179 (10) 6889-6900; DOI: https://doi.org/10.4049/jimmunol.179.10.6889
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LIGHT Is Critical for IL-12 Production by Dendritic Cells, Optimal CD4⁺ Th1 Cell Response, and Resistance to Leishmania major
Guilian Xu, Dong Liu, Ifeoma Okwor, Yang Wang, Heinrich Korner, Sam K. P. Kung, Yang-Xin Fu and Jude E. Uzonna

J Immunol November 15, 2007, 179 (10) 6901-6909; DOI: https://doi.org/10.4049/jimmunol.179.10.6901
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CCAAT/Enhancer-Binding Protein β and δ Binding to CIITA Promoters Is Associated with the Inhibition of CIITA Expression in Response to Mycobacterium tuberculosis 19-kDa Lipoprotein
Meghan E. Pennini, Yi Liu, Jianqi Yang, Colleen M. Croniger, W. Henry Boom and Clifford V. Harding

J Immunol November 15, 2007, 179 (10) 6910-6918; DOI: https://doi.org/10.4049/jimmunol.179.10.6910
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Progression of Pulmonary Tuberculosis and Efficiency of Bacillus Calmette-Guérin Vaccination Are Genetically Controlled via a Common sst1-Mediated Mechanism of Innate Immunity
Bo-Shiun Yan, Alexander V. Pichugin, Ousman Jobe, Laura Helming, Evgeniy B. Eruslanov, José A. Gutiérrez-Pabello, Mauricio Rojas, Yuriy V. Shebzukhov, Lester Kobzik and Igor Kramnik

J Immunol November 15, 2007, 179 (10) 6919-6932; DOI: https://doi.org/10.4049/jimmunol.179.10.6919
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Inflammasome-Mediated Production of IL-1β Is Required for Neutrophil Recruitment against Staphylococcus aureus In Vivo
Lloyd S. Miller, Eric M. Pietras, Lawrence H. Uricchio, Kathleen Hirano, Shyam Rao, Heping Lin, Ryan M. O’Connell, Yoichiro Iwakura, Ambrose L. Cheung, Genhong Cheng and Robert L. Modlin

J Immunol November 15, 2007, 179 (10) 6933-6942; DOI: https://doi.org/10.4049/jimmunol.179.10.6933
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Noduler, A Novel Immune Up-Regulated Protein Mediates Nodulation Response in Insects
Archana S. Gandhe, Serene H. John and Javaregowda Nagaraju

J Immunol November 15, 2007, 179 (10) 6943-6951; DOI: https://doi.org/10.4049/jimmunol.179.10.6943
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The Aryl Hydrocarbon Receptor Is Required for Optimal Resistance to Listeria monocytogenes Infection in Mice
Lewis Zhichang Shi, Nancy G. Faith, Yumi Nakayama, Makulasiddappa Suresh, Howard Steinberg and Charles J. Czuprynski

J Immunol November 15, 2007, 179 (10) 6952-6962; DOI: https://doi.org/10.4049/jimmunol.179.10.6952
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Impaired Macrophage Function Underscores Susceptibility to Salmonella in Mice Lacking Irgm1 (LRG-47)
Stanley C. Henry, Xiaojou Daniell, Maanasa Indaram, John F. Whitesides, Gregory D. Sempowski, David Howell, Tim Oliver and Gregory A. Taylor

J Immunol November 15, 2007, 179 (10) 6963-6972; DOI: https://doi.org/10.4049/jimmunol.179.10.6963
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HIV Impairs TNF-α Mediated Macrophage Apoptotic Response to Mycobacterium tuberculosis
Naimish R. Patel, Jinping Zhu, Souvenir D. Tachado, Jianmin Zhang, Zhi Wan, Jussi Saukkonen and Henry Koziel

J Immunol November 15, 2007, 179 (10) 6973-6980; DOI: https://doi.org/10.4049/jimmunol.179.10.6973
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Altered Inflammatory Responses in TLR5-Deficient Mice Infected with Legionella pneumophila
Thomas R. Hawn, William R. Berrington, Ian A. Smith, Satoshi Uematsu, Shizuo Akira, Alan Aderem, Kelly D. Smith and Shawn J. Skerrett

J Immunol November 15, 2007, 179 (10) 6981-6987; DOI: https://doi.org/10.4049/jimmunol.179.10.6981

INFLAMMATION

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Differential Expression of Inflammatory and Fibrogenic Genes and Their Regulation by NF-κB Inhibition in a Mouse Model of Chronic Colitis
Feng Wu and Shukti Chakravarti

J Immunol November 15, 2007, 179 (10) 6988-7000; DOI: https://doi.org/10.4049/jimmunol.179.10.6988
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Src Tyrosine Kinases Mediate Activations of NF-κB and Integrin Signal during Lipopolysaccharide-Induced Acute Lung Injury
Hui S. Lee, Changsuk Moon, Hye W. Lee, Eun-Mi Park, Min-Sun Cho and Jihee L. Kang

J Immunol November 15, 2007, 179 (10) 7001-7011; DOI: https://doi.org/10.4049/jimmunol.179.10.7001
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Resistin-Like Molecule β (RELMβ/FIZZ2) Is Highly Expressed in the Ileum of SAMP1/YitFc Mice and Is Associated with Initiation of Ileitis
Sean L. Barnes, Alda Vidrich, Mei-Lun Wang, Gary D. Wu, Fabio Cominelli, Jesus Rivera-Nieves, Giorgos Bamias and Steven M. Cohn

J Immunol November 15, 2007, 179 (10) 7012-7020; DOI: https://doi.org/10.4049/jimmunol.179.10.7012
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Resolvin E1 Regulates Inflammation at the Cellular and Tissue Level and Restores Tissue Homeostasis In Vivo
Hatice Hasturk, Alpdogan Kantarci, Emilie Goguet-Surmenian, Amanda Blackwood, Chris Andry, Charles N. Serhan and Thomas E. Van Dyke

J Immunol November 15, 2007, 179 (10) 7021-7029; DOI: https://doi.org/10.4049/jimmunol.179.10.7021
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Inhibition of NF-κB Activation Reduces the Tissue Effects of Transgenic IL-13
Svetlana P. Chapoval, Amal Al-Garawi, Jose M. Lora, Ian Strickland, Bing Ma, Patty J. Lee, Robert J. Homer, Sankar Ghosh, Anthony J. Coyle and Jack A. Elias

J Immunol November 15, 2007, 179 (10) 7030-7041; DOI: https://doi.org/10.4049/jimmunol.179.10.7030
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TNF Pretreatment Interferes with Mitochondrial Apoptosis in the Mouse Liver by A20-Mediated Down-Regulation of Bax
Gabriele Sass, Noula Dattu Shembade, Florian Haimerl, Nicolas Lamoureux, Said Hashemolhosseini, Andrea Tannapfel and Gisa Tiegs

J Immunol November 15, 2007, 179 (10) 7042-7049; DOI: https://doi.org/10.4049/jimmunol.179.10.7042
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Resolution of Der p1-Induced Allergic Airway Inflammation Is Dependent on CD4⁺CD25⁺Foxp3⁺ Regulatory Cells
Melanie D. Leech, Robert A. Benson, Annick deVries, Paul M. Fitch and Sarah E. M. Howie

J Immunol November 15, 2007, 179 (10) 7050-7058; DOI: https://doi.org/10.4049/jimmunol.179.10.7050
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FcεRI- and Fcγ Receptor-Mediated Production of Reactive Oxygen Species by Mast Cells Is Lipoxygenase- and Cyclooxygenase-Dependent and NADPH Oxidase-Independent
Emily J. Swindle, John W. Coleman, Frank R. DeLeo and Dean D. Metcalfe

J Immunol November 15, 2007, 179 (10) 7059-7071; DOI: https://doi.org/10.4049/jimmunol.179.10.7059
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Catalytically Inactive Cyclooxygenase 2 and Absence of Prostaglandin E₂ Biosynthesis in Murine Peritoneal Macrophages following In Vivo Phagocytosis of Heat-Killed Mycobacterium bovis Bacillus Calmette-Guérin
Makiko Yamashita, Tsutomu Shinohara, Shoutaro Tsuji, Quentin N. Myrvik, Akihito Nishiyama, Ruth Ann Henriksen and Yoshimi Shibata

J Immunol November 15, 2007, 179 (10) 7072-7078; DOI: https://doi.org/10.4049/jimmunol.179.10.7072
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Involvement of Vitronectin in Lipopolysaccaride-Induced Acute Lung Injury
Yuko Tsuruta, Young-Jun Park, Gene P. Siegal, Gang Liu and Edward Abraham

J Immunol November 15, 2007, 179 (10) 7079-7086; DOI: https://doi.org/10.4049/jimmunol.179.10.7079
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Overexpression of Bcl_XL in B Cells Promotes Th1 Response and Exacerbates Collagen-Induced Arthritis
Biao Zheng, Ekaterina Marinova, Kirsten Switzer, Daniel Wansley, Hongxia He, Roy Bheekha-Escura, Timothy W. Behrens and Shuhua Han

J Immunol November 15, 2007, 179 (10) 7087-7092; DOI: https://doi.org/10.4049/jimmunol.179.10.7087
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Mast Cells and Basophils Are Selectively Activated In Vitro and In Vivo through CD200R3 in an IgE-Independent Manner
Toshiyuki Kojima, Kazushige Obata, Kaori Mukai, Shingo Sato, Toshiyuki Takai, Yoshiyuki Minegishi and Hajime Karasuyama

J Immunol November 15, 2007, 179 (10) 7093-7100; DOI: https://doi.org/10.4049/jimmunol.179.10.7093
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MAPK p38 Regulates Transcriptional Activity of NF-κB in Primary Human Astrocytes via Acetylation of p65
Ramendra N. Saha, Malabendu Jana and Kalipada Pahan

J Immunol November 15, 2007, 179 (10) 7101-7109; DOI: https://doi.org/10.4049/jimmunol.179.10.7101
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Induction of IRAK-M Is Associated with Lipopolysaccharide Tolerance in a Human Endotoxemia Model
Cornelis van ‘t Veer, Petra S. van den Pangaart, Marieke A. D. van Zoelen, Martijn de Kruif, Rakesh S. Birjmohun, Eric S. Stroes, Alex F. de Vos and Tom van der Poll

J Immunol November 15, 2007, 179 (10) 7110-7120; DOI: https://doi.org/10.4049/jimmunol.179.10.7110
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Apigenin Blocks Lipopolysaccharide-Induced Lethality In Vivo and Proinflammatory Cytokines Expression by Inactivating NF-κB through the Suppression of p65 Phosphorylation
Courtney Nicholas, Sanjay Batra, Melissa A. Vargo, Oliver H. Voss, Mikhail A. Gavrilin, Mark D. Wewers, Denis C. Guttridge, Erich Grotewold and Andrea I. Doseff

J Immunol November 15, 2007, 179 (10) 7121-7127; DOI: https://doi.org/10.4049/jimmunol.179.10.7121
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IL-17B and IL-17C Are Associated with TNF-α Production and Contribute to the Exacerbation of Inflammatory Arthritis
Yumi Yamaguchi, Keishi Fujio, Hirofumi Shoda, Akiko Okamoto, Nelson H. Tsuno, Koki Takahashi and Kazuhiko Yamamoto

J Immunol November 15, 2007, 179 (10) 7128-7136; DOI: https://doi.org/10.4049/jimmunol.179.10.7128

CLINICAL IMMUNOLOGY

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Extracellular Branched-Chain Amino Acids, Especially Valine, Regulate Maturation and Function of Monocyte-Derived Dendritic Cells
Eiji Kakazu, Noriatsu Kanno, Yoshiyuki Ueno and Tooru Shimosegawa

J Immunol November 15, 2007, 179 (10) 7137-7146; DOI: https://doi.org/10.4049/jimmunol.179.10.7137
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Jak2 Dampens the Induction by IL-1β of Prostaglandin Endoperoxide H Synthase 2 Expression in Human Orbital Fibroblasts: Evidence for Divergent Influence on the Prostaglandin E₂ Biosynthetic Pathway
Rui Han, Beiling Chen and Terry J. Smith

J Immunol November 15, 2007, 179 (10) 7147-7156; DOI: https://doi.org/10.4049/jimmunol.179.10.7147
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IL-21 Administration into the Nostril Alleviates Murine Allergic Rhinitis
Yayoi Hiromura, Tsunao Kishida, Hiroshi Nakano, Takemitsu Hama, Jiro Imanishi, Yasuo Hisa and Osam Mazda

J Immunol November 15, 2007, 179 (10) 7157-7165; DOI: https://doi.org/10.4049/jimmunol.179.10.7157
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Elevated Urinary VCAM-1, P-Selectin, Soluble TNF Receptor-1, and CXC Chemokine Ligand 16 in Multiple Murine Lupus Strains and Human Lupus Nephritis
Tianfu Wu, Chun Xie, Hong W. Wang, Xin J. Zhou, Noa Schwartz, Sergio Calixto, Meggan Mackay, Cynthia Aranow, Chaim Putterman and Chandra Mohan

J Immunol November 15, 2007, 179 (10) 7166-7175; DOI: https://doi.org/10.4049/jimmunol.179.10.7166
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IFN-γ Produced by Human Papilloma Virus-18 E6-Specific CD4⁺ T Cells Predicts the Clinical Outcome after Surgery in Patients with High-Grade Cervical Lesions
Samantha Seresini, Massimo Origoni, Flavia Lillo, Luigi Caputo, Anna Maria Paganoni, Simone Vantini, Renato Longhi, Gianluca Taccagni, Augusto Ferrari, Claudio Doglioni, Piercesare Secchi and Maria Pia Protti

J Immunol November 15, 2007, 179 (10) 7176-7183; DOI: https://doi.org/10.4049/jimmunol.179.10.7176

CORRECTIONS

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Tolerization of tumor-specific T cells despite efficient initial priming in a primary murine model of prostate cancer.
M. J. Anderson, K. Shafer-Weaver, N. M. Greenberg and A. A. Hurwitz

J Immunol November 15, 2007, 179 (10) 7184; DOI: https://doi.org/10.4049/jimmunol.179.10.7184
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C57BL/6 mice genetically deficient in IL-12/IL-23 and IFN-γ are susceptible to experimental autoimmune myasthenia gravis, suggesting a pathogenic role of non-Th1 cells.
W. Wang, M. Milani, N. Ostlie, D. Okita, R. K. Agarwal, R. Caspi and B. M. Conti-Fine

J Immunol November 15, 2007, 179 (10) 7184; DOI: https://doi.org/10.4049/jimmunol.179.10.7184-a
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CCL19 and CXL13 synergistically regulate interaction between B cell acute lymphocytic leukemia CD23⁺CD25⁺ B cells and CD8⁺ T cells.
X. Wang, H. Yuling, J. Yanping, T. Xinti, Y. Yaofang, Y. Feng, X. Ruijin, W. Li, C. Lang and L. Jingyi

J Immunol November 15, 2007, 179 (10) 7184; DOI: https://doi.org/10.4049/jimmunol.179.10.7184-b
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Complement-dependent enhancement of CD8⁺ T cell immunity to lymphocytic choriomeningitis virus infection in decay-accelerating factor-deficient mice.
C. Fang, T. Miwa, H. Shen and W.-C. Song

J Immunol November 15, 2007, 179 (10) 7185; DOI: https://doi.org/10.4049/jimmunol.179.10.7185
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Cutting edge: a critical role of nitrogen oxide in preventing inflammation upon apoptotic cell clearance.
T. Shibata, K. Nagata and Y. Kobayashi

J Immunol November 15, 2007, 179 (10) 7185; DOI: https://doi.org/10.4049/jimmunol.179.10.7185-a
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Lymphotoxin αβ2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice.
G. Xu, D. Liu, Y. Fan, X. Yang, H. Korner, Y.-X. Fu and J. E. Uzonna

J Immunol November 15, 2007, 179 (10) 7185; DOI: https://doi.org/10.4049/jimmunol.179.10.7185-b

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Table of Contents

IN THIS ISSUE

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

IN THIS ISSUE

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

This Issue

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