The Journal of Immunology: 177 (8)

October 15, 2006; Volume 177,Issue 8

IN THIS ISSUE

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IN THIS ISSUE

J Immunol October 15, 2006, 177 (8) 4943-4944; DOI: https://doi.org/10.4049/jimmunol.177.8.4943

BRIEF REVIEWS

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Autophagy: Eating for Good Health
Michele S. Swanson

J Immunol October 15, 2006, 177 (8) 4945-4951; DOI: https://doi.org/10.4049/jimmunol.177.8.4945

CUTTING EDGE

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Cutting Edge: Treatment of Complement Regulatory Protein Deficiency by Retroviral In Vivo Gene Therapy
Dirk Spitzer, Xiaobo Wu, Xiucui Ma, Lingfei Xu, Katherine P. Ponder and John P. Atkinson

J Immunol October 15, 2006, 177 (8) 4953-4956; DOI: https://doi.org/10.4049/jimmunol.177.8.4953
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Cutting Edge: Abortive Proliferation of CD46-Induced Tr1-Like Cells due to a Defective Akt/Survivin Signaling Pathway
Grégory Meiffren, Monique Flacher, Olga Azocar, Chantal Rabourdin-Combe and Mathias Faure

J Immunol October 15, 2006, 177 (8) 4957-4961; DOI: https://doi.org/10.4049/jimmunol.177.8.4957
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Cutting Edge: Hypoxia-Inducible Factor 1α and Its Activation-Inducible Short Isoform I.1 Negatively Regulate Functions of CD4⁺ and CD8⁺ T Lymphocytes
Dmitriy Lukashev, Boris Klebanov, Hidefumi Kojima, Alex Grinberg, Akiko Ohta, Ludmilla Berenfeld, Roland H. Wenger, Akio Ohta and Michail Sitkovsky

J Immunol October 15, 2006, 177 (8) 4962-4965; DOI: https://doi.org/10.4049/jimmunol.177.8.4962
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Cutting Edge: Inhibition of T Cell Activation by TIM-2
Jared E. Knickelbein, Anjali J. de Souza, Richard Tosti, Preeti Narayan and Lawrence P. Kane

J Immunol October 15, 2006, 177 (8) 4966-4970; DOI: https://doi.org/10.4049/jimmunol.177.8.4966

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Effect of Lipid Rafts on Cb2 Receptor Signaling and 2-Arachidonoyl-Glycerol Metabolism in Human Immune Cells
Monica Bari, Paola Spagnuolo, Filomena Fezza, Sergio Oddi, Nicoletta Pasquariello, Alessandro Finazzi-Agrò and Mauro Maccarrone

J Immunol October 15, 2006, 177 (8) 4971-4980; DOI: https://doi.org/10.4049/jimmunol.177.8.4971
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DAP12 Signaling Directly Augments Proproliferative Cytokine Stimulation of NK Cells during Viral Infections
Anthony R. French, Hanna Sjölin, Sungjin Kim, Rima Koka, Liping Yang, Deborah A. Young, Cristina Cerboni, Elena Tomasello, Averil Ma, Eric Vivier, Klas Kärre and Wayne M. Yokoyama

J Immunol October 15, 2006, 177 (8) 4981-4990; DOI: https://doi.org/10.4049/jimmunol.177.8.4981
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Role of Galectin-3 in Mast Cell Functions: Galectin-3-Deficient Mast Cells Exhibit Impaired Mediator Release and Defective JNK Expression
Huan-Yuan Chen, Bhavya B. Sharma, Lan Yu, Riaz Zuberi, I-Chun Weng, Yuko Kawakami, Toshiaki Kawakami, Daniel K. Hsu and Fu-Tong Liu

J Immunol October 15, 2006, 177 (8) 4991-4997; DOI: https://doi.org/10.4049/jimmunol.177.8.4991
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Differential Usage of Cellular Niches by Cytomegalovirus versus EBV- and Influenza Virus-Specific CD8⁺ T Cells
Ester M. M. van Leeuwen, Jasper J. Koning, Ester B. M. Remmerswaal, Debbie van Baarle, René A. W. van Lier and Ineke J. M. ten Berge

J Immunol October 15, 2006, 177 (8) 4998-5005; DOI: https://doi.org/10.4049/jimmunol.177.8.4998
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IFN-γ-Mediated Inhibition of Human IgE Synthesis by IL-21 Is Associated with a Polymorphism in the IL-21R Gene
Jérôme Pène, Laurence Guglielmi, Jean-François Gauchat, Nathalie Harrer, Maximilian Woisetschläger, Vera Boulay, Jean-Michel Fabre, Pascal Demoly and Hans Yssel

J Immunol October 15, 2006, 177 (8) 5006-5013; DOI: https://doi.org/10.4049/jimmunol.177.8.5006
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Peripheral T Cell Lymphopenia and Concomitant Enrichment in Naturally Arising Regulatory T Cells: The Case of the Pre-Tα Gene-Deleted Mouse
Nabil Bosco, Fabien Agenes, Antonius G. Rolink and Rhodri Ceredig

J Immunol October 15, 2006, 177 (8) 5014-5023; DOI: https://doi.org/10.4049/jimmunol.177.8.5014
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Vav1 Promotes T Cell Cycle Progression by Linking TCR/CD28 Costimulation to FOXO1 and p27^kip1 Expression
Céline Charvet, Ann Janette Canonigo, Stéphane Bécart, Ulrich Maurer, Ana V. Miletic, Wojciech Swat, Marcel Deckert and Amnon Altman

J Immunol October 15, 2006, 177 (8) 5024-5031; DOI: https://doi.org/10.4049/jimmunol.177.8.5024
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A Preferential Role for STAT5, not Constitutively Active STAT3, in Promoting Survival of a Human Lymphoid Tumor
Zsuzsanna S. Nagy, Hallgeir Rui, Stanislaw M. Stepkowski, James Karras and Robert A. Kirken

J Immunol October 15, 2006, 177 (8) 5032-5040; DOI: https://doi.org/10.4049/jimmunol.177.8.5032
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Evidence for a Role for Notch Signaling in the Cytokine-Dependent Survival of Activated T Cells
Geetha Bheeshmachar, Divya Purushotaman, Hadassah Sade, Vigneshkumar Gunasekharan, Annapoorni Rangarajan and Apurva Sarin

J Immunol October 15, 2006, 177 (8) 5041-5050; DOI: https://doi.org/10.4049/jimmunol.177.8.5041
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Identification of a Novel Human Granzyme B Inhibitor Secreted by Cultured Sertoli Cells
Simonetta Sipione, Katia C. Simmen, Sarah J. Lord, Bruce Motyka, Catherine Ewen, Irene Shostak, Gina R. Rayat, Jannette M. Dufour, Greg S. Korbutt, Ray V. Rajotte and R. Chris Bleackley

J Immunol October 15, 2006, 177 (8) 5051-5058; DOI: https://doi.org/10.4049/jimmunol.177.8.5051
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Involvement of the IκB Kinase (IKK)-Related Kinases Tank-Binding Kinase 1/IKKi and Cullin-Based Ubiquitin Ligases in IFN Regulatory Factor-3 Degradation
Annie Bibeau-Poirier, Simon-Pierre Gravel, Jean-François Clément, Sébastien Rolland, Geneviève Rodier, Philippe Coulombe, John Hiscott, Nathalie Grandvaux, Sylvain Meloche and Marc J. Servant

J Immunol October 15, 2006, 177 (8) 5059-5067; DOI: https://doi.org/10.4049/jimmunol.177.8.5059
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The Peroxisome Proliferator-Activated Receptor γ (PPARγ) Ligands 15-Deoxy-Δ^12,14-Prostaglandin J₂ and Ciglitazone Induce Human B Lymphocyte and B Cell Lymphoma Apoptosis by PPARγ-Independent Mechanisms
Denise M. Ray, Filiz Akbiyik and Richard P. Phipps

J Immunol October 15, 2006, 177 (8) 5068-5076; DOI: https://doi.org/10.4049/jimmunol.177.8.5068
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RANTES Modulates TLR4-Induced Cytokine Secretion in Human Peripheral Blood Monocytes
Shiva Shahrara, Christy C. Park, Vladislav Temkin, Jared W. Jarvis, Michael V. Volin and Richard M. Pope

J Immunol October 15, 2006, 177 (8) 5077-5087; DOI: https://doi.org/10.4049/jimmunol.177.8.5077
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Levels of Specific Peptide-HLA Class I Complex Predicts Tumor Cell Susceptibility to CTL Killing
Jon A. Weidanz, Tiffany Nguyen, Tito Woodburn, Francisca A. Neethling, Maurizio Chiriva-Internati, William H. Hildebrand and Joseph Lustgarten

J Immunol October 15, 2006, 177 (8) 5088-5097; DOI: https://doi.org/10.4049/jimmunol.177.8.5088
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H2-M3-Restricted T Cells Participate in the Priming of Antigen-Specific CD4⁺ T Cells
Michael T. Chow, Salim Dhanji, Jennifer Cross, Pauline Johnson and Hung-Sia Teh

J Immunol October 15, 2006, 177 (8) 5098-5104; DOI: https://doi.org/10.4049/jimmunol.177.8.5098
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A 20-Mb Region of Chromosome 4 Controls TNF-α-Mediated CD8⁺ T Cell Aggression Toward β Cells in Type 1 Diabetes
Giselle Chamberlain, Maja Wållberg, Dan Rainbow, Kara Hunter, Linda S. Wicker and E. Allison Green

J Immunol October 15, 2006, 177 (8) 5105-5114; DOI: https://doi.org/10.4049/jimmunol.177.8.5105
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Selective Availability of IL-2 Is a Major Determinant Controlling the Production of CD4⁺CD25⁺Foxp3⁺ T Regulatory Cells
Aixin Yu and Thomas R. Malek

J Immunol October 15, 2006, 177 (8) 5115-5121; DOI: https://doi.org/10.4049/jimmunol.177.8.5115
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The p110δ Isoform of Phosphoinositide 3-Kinase Controls Clonal Expansion and Differentiation of Th Cells
Klaus Okkenhaug, Daniel T. Patton, Antonio Bilancio, Fabien Garçon, Wendy C. Rowan and Bart Vanhaesebroeck

J Immunol October 15, 2006, 177 (8) 5122-5128; DOI: https://doi.org/10.4049/jimmunol.177.8.5122
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Tetraspanins CD9 and CD81 Modulate HIV-1-Induced Membrane Fusion
Mónica Gordón-Alonso, María Yañez-Mó, Olga Barreiro, Susana Álvarez, M. Ángeles Muñoz-Fernández, Agustín Valenzuela-Fernández and Francisco Sánchez-Madrid

J Immunol October 15, 2006, 177 (8) 5129-5137; DOI: https://doi.org/10.4049/jimmunol.177.8.5129
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IL-10- and IL-12-Independent Down-Regulation of Allergic Sensitization by Stimulation of CD40 Signaling
Peter W. Hellings, Ahmad Kasran, Dominique Bullens, Lutgart Overbergh, Chantal Mathieu, Hubertine Heremans, Patrick Matthys, Louis Boon, Mark Jorissen and Jan L. Ceuppens

J Immunol October 15, 2006, 177 (8) 5138-5144; DOI: https://doi.org/10.4049/jimmunol.177.8.5138
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High Cytotoxic and Specific Migratory Potencies of Senescent CD8⁺CD57⁺ Cells in HIV-Infected and Uninfected Individuals
Yannick Le Priol, Denis Puthier, Cédric Lécureuil, Christophe Combadière, Patrice Debré, Catherine Nguyen and Béhazine Combadière

J Immunol October 15, 2006, 177 (8) 5145-5154; DOI: https://doi.org/10.4049/jimmunol.177.8.5145
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A Novel Mechanism for Complement Activation at the Surface of B Cells Following Antigen Binding
Anthony P. Manderson, Ben Quah, Marina Botto, Chris C. Goodnow, Mark J. Walport and Chris R. Parish

J Immunol October 15, 2006, 177 (8) 5155-5162; DOI: https://doi.org/10.4049/jimmunol.177.8.5155
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Autophagy Is Induced in CD4⁺ T Cells and Important for the Growth Factor-Withdrawal Cell Death
Changyou Li, Elizabeth Capan, Yani Zhao, Jianping Zhao, Donna Stolz, Simon C. Watkins, Shengkan Jin and Binfeng Lu

J Immunol October 15, 2006, 177 (8) 5163-5168; DOI: https://doi.org/10.4049/jimmunol.177.8.5163
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The Cyclin-Dependent Kinase Inhibitor p27^kip1 Is Required for Transplantation Tolerance Induced by Costimulatory Blockade
Emily A. Rowell, Liqing Wang, Wayne W. Hancock and Andrew D. Wells

J Immunol October 15, 2006, 177 (8) 5169-5176; DOI: https://doi.org/10.4049/jimmunol.177.8.5169
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The Src Homology 2 Domain-Containing Leukocyte Protein of 76-kDa Adaptor Links Integrin Ligation with p44/42 MAPK Phosphorylation and Podosome Distribution in Murine Dendritic Cells
Nancy A. Luckashenak, Rebecca L. Ryszkiewicz, Kimberley D. Ramsey and James L. Clements

J Immunol October 15, 2006, 177 (8) 5177-5185; DOI: https://doi.org/10.4049/jimmunol.177.8.5177
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Aspergillus fumigatus Generates an Enhanced Th2-Biased Immune Response in Mice with Defective Cystic Fibrosis Transmembrane Conductance Regulator
Jenna B. Allard, Matthew E. Poynter, Kieren A. Marr, Lauren Cohn, Mercedes Rincon and Laurie A. Whittaker

J Immunol October 15, 2006, 177 (8) 5186-5194; DOI: https://doi.org/10.4049/jimmunol.177.8.5186
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Distinct Characteristics of Murine STAT4 Activation in Response to IL-12 and IFN-α
Lisa S. Berenson, Maya Gavrieli, J. David Farrar, Theresa L. Murphy and Kenneth M. Murphy

J Immunol October 15, 2006, 177 (8) 5195-5203; DOI: https://doi.org/10.4049/jimmunol.177.8.5195
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Establishment of Lymphotoxin β Receptor Signaling-Dependent Cell Lines with Follicular Dendritic Cell Phenotypes from Mouse Lymph Nodes
Yumiko Nishikawa, Masaki Hikida, Masaki Magari, Naoki Kanayama, Masaharu Mori, Hiroshi Kitamura, Tomohiro Kurosaki and Hitoshi Ohmori

J Immunol October 15, 2006, 177 (8) 5204-5214; DOI: https://doi.org/10.4049/jimmunol.177.8.5204
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DOCK2 is Required for Chemokine-Promoted Human T Lymphocyte Adhesion Under Shear Stress Mediated by the Integrin α₄β₁
David García-Bernal, Elena Sotillo-Mallo, César Nombela-Arrieta, Rafael Samaniego, Yoshinori Fukui, Jens V. Stein and Joaquin Teixidó

J Immunol October 15, 2006, 177 (8) 5215-5225; DOI: https://doi.org/10.4049/jimmunol.177.8.5215
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Expression of CD1d Molecules by Human Schwann Cells and Potential Interactions with Immunoregulatory Invariant NK T Cells
Jin S. Im, Nikos Tapinos, Gue-Tae Chae, Petr A. Illarionov, Gurdyal S. Besra, George H. DeVries, Robert L. Modlin, Peter A. Sieling, Anura Rambukkana and Steven A. Porcelli

J Immunol October 15, 2006, 177 (8) 5226-5235; DOI: https://doi.org/10.4049/jimmunol.177.8.5226
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Kinetics of Human B Cell Behavior and Amplification of Proliferative Responses following Stimulation with IL-21
Kim L. Good, Vanessa L. Bryant and Stuart G. Tangye

J Immunol October 15, 2006, 177 (8) 5236-5247; DOI: https://doi.org/10.4049/jimmunol.177.8.5236
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Modulation of Airway Remodeling and Airway Inflammation by Peroxisome Proliferator-Activated Receptor γ in a Murine Model of Toluene Diisocyanate-Induced Asthma
Kyung Sun Lee, Seoung Ju Park, So Ri Kim, Kyung Hoon Min, Sun Mi Jin, Hern Ku Lee and Yong Chul Lee

J Immunol October 15, 2006, 177 (8) 5248-5257; DOI: https://doi.org/10.4049/jimmunol.177.8.5248
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IL-4-Secreting NKT Cells Prevent Hypersensitivity Pneumonitis by Suppressing IFN-γ-Producing Neutrophils
Su Jin Hwang, Sanghee Kim, Weon Seo Park and Doo Hyun Chung

J Immunol October 15, 2006, 177 (8) 5258-5268; DOI: https://doi.org/10.4049/jimmunol.177.8.5258
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Innate Response to Focal Necrotic Injury Inside the Blood-Brain Barrier
Jiyun V. Kim and Michael L. Dustin

J Immunol October 15, 2006, 177 (8) 5269-5277; DOI: https://doi.org/10.4049/jimmunol.177.8.5269
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Dendritic Cells Expressing Transgenic Galectin-1 Delay Onset of Autoimmune Diabetes in Mice
Marcelo J. Perone, Suzanne Bertera, Zakaria S. Tawadrous, William J. Shufesky, Jon D. Piganelli, Linda G. Baum, Massimo Trucco and Adrian E. Morelli

J Immunol October 15, 2006, 177 (8) 5278-5289; DOI: https://doi.org/10.4049/jimmunol.177.8.5278
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CXCR5 Identifies a Subset of Vγ9Vδ2 T Cells which Secrete IL-4 and IL-10 and Help B Cells for Antibody Production
Nadia Caccamo, Luca Battistini, Marc Bonneville, Fabrizio Poccia, Jean Jacques Fournié, Serena Meraviglia, Giovanna Borsellino, Richard A. Kroczek, Carmela La Mendola, Emmanuel Scotet, Francesco Dieli and Alfredo Salerno

J Immunol October 15, 2006, 177 (8) 5290-5295; DOI: https://doi.org/10.4049/jimmunol.177.8.5290
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Suppression of Experimental Autoimmune Myasthenia Gravis by Granulocyte-Macrophage Colony-Stimulating Factor Is Associated with an Expansion of FoxP3⁺ Regulatory T Cells
Jian Rong Sheng, Liangcheng Li, Balaji B. Ganesh, Chenthamarakshan Vasu, Bellur S. Prabhakar and Matthew N. Meriggioli

J Immunol October 15, 2006, 177 (8) 5296-5306; DOI: https://doi.org/10.4049/jimmunol.177.8.5296
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Absence of Innate MyD88 Signaling Promotes Inducible Allograft Acceptance
Wendy E. Walker, Isam W. Nasr, Geoffrey Camirand, Bethany M. Tesar, Carmen J. Booth and Daniel R. Goldstein

J Immunol October 15, 2006, 177 (8) 5307-5316; DOI: https://doi.org/10.4049/jimmunol.177.8.5307
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SAP Is Required for Th Cell Function and for Immunity to Influenza
Cris Kamperschroer, John P. Dibble, Dana L. Meents, Pamela L. Schwartzberg and Susan L. Swain

J Immunol October 15, 2006, 177 (8) 5317-5327; DOI: https://doi.org/10.4049/jimmunol.177.8.5317

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Galectin-1 Binds Different CD43 Glycoforms to Cluster CD43 and Regulate T Cell Death
Joseph D. Hernandez, Julie T. Nguyen, Jiale He, Wei Wang, Blair Ardman, Jonathan M. Green, Minoru Fukuda and Linda G. Baum

J Immunol October 15, 2006, 177 (8) 5328-5336; DOI: https://doi.org/10.4049/jimmunol.177.8.5328
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ERK Signaling Is a Molecular Switch Integrating Opposing Inputs from B Cell Receptor and T Cell Cytokines to Control TLR4-Driven Plasma Cell Differentiation
Lixin Rui, James I. Healy, Julie Blasioli and Christopher C. Goodnow

J Immunol October 15, 2006, 177 (8) 5337-5346; DOI: https://doi.org/10.4049/jimmunol.177.8.5337
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A Single Polymorphism Disrupts the Killer Ig-Like Receptor 2DL2/2DL3 D1 Domain
Christopher J. VandenBussche, Sivanesan Dakshanamurthy, Phillip E. Posch and Carolyn Katovich Hurley

J Immunol October 15, 2006, 177 (8) 5347-5357; DOI: https://doi.org/10.4049/jimmunol.177.8.5347
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Stochastic Monoallelic Expression of IL-10 in T Cells
Dinis Pedro Calado, Tiago Paixão, Dan Holmberg and Matthias Haury

J Immunol October 15, 2006, 177 (8) 5358-5364; DOI: https://doi.org/10.4049/jimmunol.177.8.5358
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Differential and Nonredundant Roles of Phospholipase Cγ2 and Phospholipase Cγ1 in the Terminal Maturation of NK Cells
Jeyarani Regunathan, Yuhong Chen, Snjezana Kutlesa, Xuezhi Dai, Li Bai, Renren Wen, Demin Wang and Subramaniam Malarkannan

J Immunol October 15, 2006, 177 (8) 5365-5376; DOI: https://doi.org/10.4049/jimmunol.177.8.5365
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Two-Sided Roles of IL-27: Induction of Th1 Differentiation on Naive CD4⁺ T Cells versus Suppression of Proinflammatory Cytokine Production Including IL-23-Induced IL-17 on Activated CD4⁺ T Cells Partially Through STAT3-Dependent Mechanism
Takeru Yoshimura, Atsunobu Takeda, Shinjiro Hamano, Yoshiyuki Miyazaki, Ichiko Kinjyo, Tatsuro Ishibashi, Akihiko Yoshimura and Hiroki Yoshida

J Immunol October 15, 2006, 177 (8) 5377-5385; DOI: https://doi.org/10.4049/jimmunol.177.8.5377
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Somatic Hypermutation and Class Switch Recombination in Msh6^−/−Ung^−/− Double-Knockout Mice
Hong Ming Shen, Atsushi Tanaka, Grazyna Bozek, Dan Nicolae and Ursula Storb

J Immunol October 15, 2006, 177 (8) 5386-5392; DOI: https://doi.org/10.4049/jimmunol.177.8.5386
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V(D)J Recombinase-Mediated Processing of Coding Junctions at Cryptic Recombination Signal Sequences in Peripheral T Cells during Human Development
Janet M. Murray, J. Patrick O’Neill, Terri Messier, Jami Rivers, Vernon E. Walker, Brien McGonagle, Lucy Trombley, Lindsay G. Cowell, Garnett Kelsoe, Fraser McBlane and Barry A. Finette

J Immunol October 15, 2006, 177 (8) 5393-5404; DOI: https://doi.org/10.4049/jimmunol.177.8.5393
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Transitional B Cell Fate Is Associated with Developmental Stage-Specific Regulation of Diacylglycerol and Calcium Signaling upon B Cell Receptor Engagement
Kristen L. Hoek, Pierre Antony, John Lowe, Nicholas Shinners, Bhaskarjyoti Sarmah, Susan R. Wente, Demin Wang, Rachel M. Gerstein and Wasif N. Khan

J Immunol October 15, 2006, 177 (8) 5405-5413; DOI: https://doi.org/10.4049/jimmunol.177.8.5405
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Induced Expression of Murine γ2a by CD40 Ligation Independently of IFN-γ
John T. Collins, Jian Shi, Bryna E. Burrell, D. Keith Bishop and Wesley A. Dunnick

J Immunol October 15, 2006, 177 (8) 5414-5419; DOI: https://doi.org/10.4049/jimmunol.177.8.5414
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Stage-Specific Expression of Two Neighboring Crlz1 and IgJ Genes during B Cell Development Is Regulated by Their Chromatin Accessibility and Histone Acetylation
Jung-Hyun Lim, Sun-Jung Cho, Sung-Kyun Park, Jiyoung Kim, Daeho Cho, Wang Jae Lee and Chang-Joong Kang

J Immunol October 15, 2006, 177 (8) 5420-5429; DOI: https://doi.org/10.4049/jimmunol.177.8.5420
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The DMα and DMβ Chain Cooperate in the Oxidation and Folding of HLA-DM
Marcel van Lith and Adam M. Benham

J Immunol October 15, 2006, 177 (8) 5430-5439; DOI: https://doi.org/10.4049/jimmunol.177.8.5430
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Processing of a Class I-Restricted Epitope from Tyrosinase Requires Peptide N-Glycanase and the Cooperative Action of Endoplasmic Reticulum Aminopeptidase 1 and Cytosolic Proteases
Michelle L. Altrich-VanLith, Marina Ostankovitch, Joy M. Polefrone, Claudio A. Mosse, Jeffrey Shabanowitz, Donald F. Hunt and Victor H. Engelhard

J Immunol October 15, 2006, 177 (8) 5440-5450; DOI: https://doi.org/10.4049/jimmunol.177.8.5440
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CDw78 Defines MHC Class II-Peptide Complexes That Require Ii Chain-Dependent Lysosomal Trafficking, Not Localization to a Specific Tetraspanin Membrane Microdomain
Neil J. Poloso, Lisa K. Denzin and Paul A. Roche

J Immunol October 15, 2006, 177 (8) 5451-5458; DOI: https://doi.org/10.4049/jimmunol.177.8.5451

IMMUNOGENETICS

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Antibody Repertoire Development in Fetal and Neonatal Piglets. XIII. Hybrid V_H Genes and the Preimmune Repertoire Revisited
John E. Butler, Patrick Weber and Nancy Wertz

J Immunol October 15, 2006, 177 (8) 5459-5470; DOI: https://doi.org/10.4049/jimmunol.177.8.5459
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Lectin Pathway of Bony Fish Complement: Identification of Two Homologs of the Mannose-Binding Lectin Associated with MASP2 in the Common Carp (Cyprinus carpio)
Miki Nakao, Takayuki Kajiya, Yuho Sato, Tomonori Somamoto, Yoko Kato-Unoki, Misao Matsushita, Munehiro Nakata, Teizo Fujita and Tomoki Yano

J Immunol October 15, 2006, 177 (8) 5471-5479; DOI: https://doi.org/10.4049/jimmunol.177.8.5471
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Antibody Repertoire Development in Fetal and Neonatal Piglets. XVII. IgG Subclass Transcription Revisited with Emphasis on New IgG3
John E. Butler and Nancy Wertz

J Immunol October 15, 2006, 177 (8) 5480-5489; DOI: https://doi.org/10.4049/jimmunol.177.8.5480

HOST DEFENSE

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Increased Human IgE Induced by Killing Schistosoma mansoni In Vivo Is Associated with Pretreatment Th2 Cytokine Responsiveness to Worm Antigens
Klaudia Walter, Anthony J. C. Fulford, Rowena McBeath, Sarah Joseph, Frances M. Jones, H. Curtis Kariuki, Joseph K. Mwatha, Gachuhi Kimani, Narcis B. Kabatereine, Birgitte J. Vennervald, John H. Ouma and David W. Dunne

J Immunol October 15, 2006, 177 (8) 5490-5498; DOI: https://doi.org/10.4049/jimmunol.177.8.5490
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Critical Role of Prostaglandin E₂ Overproduction in Impaired Pulmonary Host Response following Bone Marrow Transplantation
Megan N. Ballinger, David M. Aronoff, Tracy R. McMillan, Kenneth R. Cooke, Krystyna Olkiewicz, Galen B. Toews, Marc Peters-Golden and Bethany B. Moore

J Immunol October 15, 2006, 177 (8) 5499-5508; DOI: https://doi.org/10.4049/jimmunol.177.8.5499
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In the Absence of Reactive Oxygen Species, T Cells Default to a Th1 Phenotype and Mediate Protection against Pulmonary Cryptococcus neoformans Infection
Robert J. Snelgrove, Lorna Edwards, Andrew E. Williams, Aaron J. Rae and Tracy Hussell

J Immunol October 15, 2006, 177 (8) 5509-5516; DOI: https://doi.org/10.4049/jimmunol.177.8.5509
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Mannose-Binding Lectin Augments the Uptake of Lipid A, Staphylococcus aureus, and Escherichia coli by Kupffer Cells through Increased Cell Surface Expression of Scavenger Receptor A
Kei Ono, Chiaki Nishitani, Hiroaki Mitsuzawa, Takeyuki Shimizu, Hitomi Sano, Hiroshi Suzuki, Tatsuhiko Kodama, Nobuhiro Fujii, Koichi Fukase, Koichi Hirata and Yoshio Kuroki

J Immunol October 15, 2006, 177 (8) 5517-5523; DOI: https://doi.org/10.4049/jimmunol.177.8.5517
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Mucosal Vaccine Targeting Improves Onset of Mucosal and Systemic Immunity to Botulinum Neurotoxin A
Massimo Maddaloni, Herman F. Staats, Dagmara Mierzejewska, Teri Hoyt, Amy Robinson, Gayle Callis, Shunji Kozaki, Hiroshi Kiyono, Jerry R. McGhee, Kohtaro Fujihashi and David W. Pascual

J Immunol October 15, 2006, 177 (8) 5524-5532; DOI: https://doi.org/10.4049/jimmunol.177.8.5524
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Release of LL-37 by Activated Human Vγ9Vδ2 T Cells: A Microbicidal Weapon against Brucella suis
Sherri Dudal, Chrystell Turriere, Stephanie Bessoles, Pascaline Fontes, Françoise Sanchez, Janny Liautard, Jean-Pierre Liautard and Virginie Lafont

J Immunol October 15, 2006, 177 (8) 5533-5539; DOI: https://doi.org/10.4049/jimmunol.177.8.5533
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Differential Modulation of Human Lactoferrin Activity against Both R5 and X4-HIV-1 Adsorption on Epithelial Cells and Dendritic Cells by Natural Antibodies
Héla Saidi, Jobin Eslaphazir, Cédric Carbonneil, Laetitia Carthagena, Mary Requena, Nadine Nassreddine and Laurent Belec

J Immunol October 15, 2006, 177 (8) 5540-5549; DOI: https://doi.org/10.4049/jimmunol.177.8.5540

INFLAMMATION

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Involvement of the Urokinase Kringle Domain in Lipopolysaccharide-Induced Acute Lung Injury
Xue-Qing Wang, Khalil Bdeir, Sergei Yarovoi, Douglas B. Cines, Wenfeng Fang and Edward Abraham

J Immunol October 15, 2006, 177 (8) 5550-5557; DOI: https://doi.org/10.4049/jimmunol.177.8.5550
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Retrovirus-Mediated Over-Expression of Decay-Accelerating Factor Rescues Crry-Deficient Erythrocytes from Acute Alternative Pathway Complement Attack
David D. Kim, Takashi Miwa and Wen-Chao Song

J Immunol October 15, 2006, 177 (8) 5558-5566; DOI: https://doi.org/10.4049/jimmunol.177.8.5558
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Membrane-Bound CC Chemokine Inhibitor 35K Provides Localized Inhibition of CC Chemokine Activity In Vitro and In Vivo
Christina A. Bursill, Jenna L. Cash, Keith M. Channon and David R. Greaves

J Immunol October 15, 2006, 177 (8) 5567-5573; DOI: https://doi.org/10.4049/jimmunol.177.8.5567
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IL-1β Regulates Blood-Brain Barrier Permeability via Reactivation of the Hypoxia-Angiogenesis Program
Azeb Tadesse Argaw, Yueting Zhang, Brian J. Snyder, Meng-Liang Zhao, Natalya Kopp, Sunhee C. Lee, Cedric S. Raine, Celia F. Brosnan and Gareth R. John

J Immunol October 15, 2006, 177 (8) 5574-5584; DOI: https://doi.org/10.4049/jimmunol.177.8.5574
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Serum Amyloid A Binding to Formyl Peptide Receptor-Like 1 Induces Synovial Hyperplasia and Angiogenesis
Mi-Sook Lee, Seung-Ah Yoo, Chul-Soo Cho, Pann-Ghill Suh, Wan-Uk Kim and Sung Ho Ryu

J Immunol October 15, 2006, 177 (8) 5585-5594; DOI: https://doi.org/10.4049/jimmunol.177.8.5585
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Inhibition of Arginase I Activity by RNA Interference Attenuates IL-13-Induced Airways Hyperresponsiveness
Ming Yang, Danny Rangasamy, Klaus I. Matthaei, Ailsa J. Frew, Nives Zimmmermann, Suresh Mahalingam, Dianne C. Webb, David J. Tremethick, Philip J. Thompson, Simon P. Hogan, Marc E. Rothenberg, William B. Cowden and Paul S. Foster

J Immunol October 15, 2006, 177 (8) 5595-5603; DOI: https://doi.org/10.4049/jimmunol.177.8.5595
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Differential Pattern of Inflammatory Molecule Regulation in Intestinal Epithelial Cells Stimulated with IL-1
Sen Rong Yan, Robbie R. Joseph, Jun Wang and Andrew W. Stadnyk

J Immunol October 15, 2006, 177 (8) 5604-5611; DOI: https://doi.org/10.4049/jimmunol.177.8.5604
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Deguelin, an Akt Inhibitor, Suppresses IκBα Kinase Activation Leading to Suppression of NF-κB-Regulated Gene Expression, Potentiation of Apoptosis, and Inhibition of Cellular Invasion
Asha S. Nair, Shishir Shishodia, Kwang Seok Ahn, Ajaikumar B. Kunnumakkara, Gautam Sethi and Bharat B. Aggarwal

J Immunol October 15, 2006, 177 (8) 5612-5622; DOI: https://doi.org/10.4049/jimmunol.177.8.5612
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Type I IFN Modulates Host Defense and Late Hyperinflammation in Septic Peritonitis
Heike Weighardt, Simone Kaiser-Moore, Sylvia Schlautkötter, Tanja Rossmann-Bloeck, Ulrike Schleicher, Christian Bogdan and Bernhard Holzmann

J Immunol October 15, 2006, 177 (8) 5623-5630; DOI: https://doi.org/10.4049/jimmunol.177.8.5623

CLINICAL IMMUNOLOGY

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Induction of IL-10 Suppressors in Lung Transplant Patients by CD4⁺25⁺ Regulatory T Cells through CTLA-4 Signaling
Ankit Bharat, Ryan C. Fields, Elbert P. Trulock, G. Alexander Patterson and Thalachallour Mohanakumar

J Immunol October 15, 2006, 177 (8) 5631-5638; DOI: https://doi.org/10.4049/jimmunol.177.8.5631
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Reinstalling Antitumor Immunity by Inhibiting Tumor-Derived Immunosuppressive Molecule IDO through RNA Interference
Xiufen Zheng, James Koropatnick, Mu Li, Xusheng Zhang, Fengjun Ling, Xiubao Ren, Xishan Hao, Hongtao Sun, Costin Vladau, Jacob A. Franek, Biao Feng, Bradley L. Urquhart, Robert Zhong, David J. Freeman, Bertha Garcia and Wei-Ping Min

J Immunol October 15, 2006, 177 (8) 5639-5646; DOI: https://doi.org/10.4049/jimmunol.177.8.5639
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Bacillus Calmette Guerin Vaccination of Human Newborns Induces a Specific, Functional CD8⁺ T Cell Response
Rose Ann Murray, Nazma Mansoor, Ryhor Harbacheuski, Jorge Soler, Virginia Davids, Andreia Soares, Anthony Hawkridge, Gregory D. Hussey, Holden Maecker, Gilla Kaplan and Willem A. Hanekom

J Immunol October 15, 2006, 177 (8) 5647-5651; DOI: https://doi.org/10.4049/jimmunol.177.8.5647
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Triosephosphate Isomerase- and Glyceraldehyde-3-Phosphate Dehydrogenase-Reactive Autoantibodies in the Cerebrospinal Fluid of Patients with Multiple Sclerosis
Johanna Kolln, Hui-Min Ren, Reng-Rong Da, Yiping Zhang, Edzard Spillner, Michael Olek, Neal Hermanowicz, Lutz G. Hilgenberg, Martin A. Smith, Stanley van den Noort and Yufen Qin

J Immunol October 15, 2006, 177 (8) 5652-5658; DOI: https://doi.org/10.4049/jimmunol.177.8.5652
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Differential Expression of CD11c by Peripheral Blood NK Cells Reflects Temporal Activity of Multiple Sclerosis
Toshimasa Aranami, Sachiko Miyake and Takashi Yamamura

J Immunol October 15, 2006, 177 (8) 5659-5667; DOI: https://doi.org/10.4049/jimmunol.177.8.5659
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Human CD4⁺ T Cells Lyse Target Cells via Granzyme/Perforin upon Circumvention of MHC Class II Restriction by an Antibody-Like Immunoreceptor
Andreas Hombach, Heike Köhler, Gunter Rappl and Hinrich Abken

J Immunol October 15, 2006, 177 (8) 5668-5675; DOI: https://doi.org/10.4049/jimmunol.177.8.5668
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Development of Autoimmunity in IL-14α-Transgenic Mice
Long Shen, Chongjie Zhang, Tao Wang, Stephen Brooks, Richard J. Ford, Yen Chiu Lin-Lee, Amy Kasianowicz, Vijay Kumar, Lisa Martin, Ping Liang, John Cowell and Julian L. Ambrus Jr

J Immunol October 15, 2006, 177 (8) 5676-5686; DOI: https://doi.org/10.4049/jimmunol.177.8.5676
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Macrophage Migration Inhibitory Factor Deficiency Attenuates Macrophage Recruitment, Glomerulonephritis, and Lethality in MRL/lpr Mice
Alberta Y. Hoi, Michael J. Hickey, Pamela Hall, Jiro Yamana, Kim M. O’Sullivan, Leilani L. Santos, Will G. James, A. Richard Kitching and Eric F. Morand

J Immunol October 15, 2006, 177 (8) 5687-5696; DOI: https://doi.org/10.4049/jimmunol.177.8.5687
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Vector Prime/Protein Boost Vaccine That Overcomes Defects Acquired during Aging and Cancer
Yucheng Tang, Hakan Akbulut, Jonathan Maynard, Line Petersen, Xiangming Fang, Wei-Wei Zhang, Xiaoqin Xia, James Koziol, Phyllis-Jean Linton and Albert Deisseroth

J Immunol October 15, 2006, 177 (8) 5697-5707; DOI: https://doi.org/10.4049/jimmunol.177.8.5697
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Amelioration of Mercury-Induced Autoimmunity by 4-1BB
Dass S. Vinay, Jung D. Kim and Byoung S. Kwon

J Immunol October 15, 2006, 177 (8) 5708-5717; DOI: https://doi.org/10.4049/jimmunol.177.8.5708
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Reduced Frequency, Diversity, and Function of Human T Cell Leukemia Virus Type 1-Specific CD8⁺ T Cell in Adult T Cell Leukemia Patients
Tomohiro Kozako, Naomichi Arima, Shingo Toji, Izumi Masamoto, Masaki Akimoto, Heiichiro Hamada, Xiao-Fang Che, Hiroshi Fujiwara, Kakushi Matsushita, Masahito Tokunaga, Koichi Haraguchi, Kimiharu Uozumi, Susumu Suzuki, Toshiro Takezaki and Shunro Sonoda

J Immunol October 15, 2006, 177 (8) 5718-5726; DOI: https://doi.org/10.4049/jimmunol.177.8.5718
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Interaction of Vascular Endothelial Growth Factor 165 with Neuropilin-1 Protects Rheumatoid Synoviocytes from Apoptotic Death by Regulating Bcl-2 Expression and Bax Translocation
Wan-Uk Kim, Soon Suk Kang, Seung-Ah Yoo, Kyung-Hee Hong, Dong-Goo Bae, Mi-Sook Lee, Seung Woo Hong, Chi-Bom Chae and Chul-Soo Cho

J Immunol October 15, 2006, 177 (8) 5727-5735; DOI: https://doi.org/10.4049/jimmunol.177.8.5727
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Innate Immune Responses to Human Malaria: Heterogeneous Cytokine Responses to Blood-Stage Plasmodium falciparum Correlate with Parasitological and Clinical Outcomes
Michael Walther, John Woodruff, Fanny Edele, David Jeffries, Jon E. Tongren, Elizabeth King, Laura Andrews, Philip Bejon, Sarah C. Gilbert, Joseph B. De Souza, Robert Sinden, Adrian V. S. Hill and Eleanor M. Riley

J Immunol October 15, 2006, 177 (8) 5736-5745; DOI: https://doi.org/10.4049/jimmunol.177.8.5736

CORRECTIONS

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Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.
C. J. Cohen, Z. Zheng, R. Bray, Y. Zhao, L. A. Sherman, S. A. Rosenberg and R. A. Morgan

J Immunol October 15, 2006, 177 (8) 5746; DOI: https://doi.org/10.4049/jimmunol.177.8.5746
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Visualization of p53_264–272/HLA-A*0201 complexes naturally presented on tumor cell surface by a multimeric soluble single-chain T cell receptor.
X. Zhu, H. J. Belmont, S. Price-Schiavi, B. Liu, H.-i. Lee, M. Fernandez, R. L. Wong, J. Builes, P. R. Rhode and H. C. Wong

J Immunol October 15, 2006, 177 (8) 5747; DOI: https://doi.org/10.4049/jimmunol.177.8.5747
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Contribution of CD8⁺ T cells to control of Mycobacterium tuberculosis infection.
D. Sud, C. Bigbee, J. L. Flynn and D. E. Kirschner

J Immunol October 15, 2006, 177 (8) 5747; DOI: https://doi.org/10.4049/jimmunol.177.8.5747-a
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Functional regulatory T cells are collected in stem cell autografts by mobilization with high-dose cyclophosphamide and granulocyte colony-stimulating factor.
M. Condomines, P. Quittet, Z.-Y. Lu, L. Nadal, P. Latry, E. Lopez, M. Baudard, G. Requirand, C. Duperray, J.-F. Schved, J.-F. Rossi, K. Tarte and B. Klein

J Immunol October 15, 2006, 177 (8) 5748; DOI: https://doi.org/10.4049/jimmunol.177.8.5748
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Accumulation of immunosuppressive CD11b⁺ myeloid cells correlates with the failure to prevent tumor growth in the anterior chamber of the eye.
K. C. McKenna and J. A. Kapp

J Immunol October 15, 2006, 177 (8) 5748; DOI: https://doi.org/10.4049/jimmunol.177.8.5748-a
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DAP12 signaling regulates plasmacytoid dendritic cell homeostasis and down-modulates their function during viral infection.
H. Sjölin, S. H. Robbins, G. Bessou, Å. Hidmark, E. Tomasello, M. Johansson, H. Hall, F. Charifi, G. B. K. Hedestam, C. A. Biron, K. Kärre, P. Höglund, E. Vivier and M. Dalod

J Immunol October 15, 2006, 177 (8) 5748; DOI: https://doi.org/10.4049/jimmunol.177.8.5748-b

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BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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