The Journal of Immunology: 177 (3)

August 1, 2006; Volume 177,Issue 3

PRESIDENTIAL ADDRESS

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Defining Yourself: Tolerance Development in the Immune System
Paul M. Allen

J Immunol August 1, 2006, 177 (3) 1369-1372; DOI: https://doi.org/10.4049/jimmunol.177.3.1369

IN THIS ISSUE

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IN THIS ISSUE

J Immunol August 1, 2006, 177 (3) 1373-1374; DOI: https://doi.org/10.4049/jimmunol.177.3.1373

LETTERS TO THE EDITOR

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Comment on “The Vast Majority of CLA⁺ T Cells Are Resident in Normal Skin”
Patrick Schaerli, Lisa M. Ebert and Bernhard Moser

J Immunol August 1, 2006, 177 (3) 1375-1376; DOI: https://doi.org/10.4049/jimmunol.177.3.1375
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Response to Comment on “The Vast Majority of CLA⁺ T Cells Are Resident in Normal Skin”
Rachael A. Clark and Thomas S. Kupper

J Immunol August 1, 2006, 177 (3) 1376-1377; DOI: https://doi.org/10.4049/jimmunol.177.3.1376
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Comment on “Mast Cell-Mediated Remodeling and Fibrinolytic Activity Protect against Fatal Glomerulonephritis”
Kathrin Hochegger, Alexander R. Rosenkranz, Frank Siebenhaar and Marcus Maurer

J Immunol August 1, 2006, 177 (3) 1377; DOI: https://doi.org/10.4049/jimmunol.177.3.1377
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Response to Comment on “Mast Cell-Mediated Remodeling and Fibrinolytic Activity Protect against Fatal Glomerulonephritis”
Yutaka Kanamaru, Lisa Scandiuzzi, Marie Essig, Renato C. Monteiro and Ulrich Blank

J Immunol August 1, 2006, 177 (3) 1377-1378; DOI: https://doi.org/10.4049/jimmunol.177.3.1377-a

PILLARS OF IMMUNOLOGY

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T Cells Stop to Smell the (Antigenic) Roses
Pamela J. Fink

J Immunol August 1, 2006, 177 (3) 1379-1380; DOI: https://doi.org/10.4049/jimmunol.177.3.1379
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Pillars Article: Antigen-Induced Selective Recruitment of Circulating Lymphocytes. Cell. Immunol. 1971. 2: 171–181.
Jonathan Sprent, Jacques F. A. P. Miller and Graham F. Mitchell

J Immunol August 1, 2006, 177 (3) 1381-1391;

BRIEF REVIEWS

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Novel Effector Molecules in Type 2 Inflammation: Lessons Drawn from Helminth Infection and Allergy
Meera G. Nair, Katherine J. Guild and David Artis

J Immunol August 1, 2006, 177 (3) 1393-1399; DOI: https://doi.org/10.4049/jimmunol.177.3.1393

CUTTING EDGE

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Cutting Edge: Lupus Susceptibility Interval Sle3/5 Confers Responsiveness to Prolactin in C57BL/6 Mice
Elena Peeva, Juana Gonzalez, Ruthmarie Hicks and Betty Diamond

J Immunol August 1, 2006, 177 (3) 1401-1405; DOI: https://doi.org/10.4049/jimmunol.177.3.1401
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Cutting Edge: Cognate CD4 Help Promotes Recruitment of Antigen-Specific CD8 T Cells around Dendritic Cells
Hélène Beuneu, Zacarias Garcia and Philippe Bousso

J Immunol August 1, 2006, 177 (3) 1406-1410; DOI: https://doi.org/10.4049/jimmunol.177.3.1406
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Cutting Edge: Central Memory T Cells Do Not Show Accelerated Proliferation or Tissue Infiltration in Response to Localized Herpes Simplex Virus-1 Infection
Angus T. Stock, Claerwen M. Jones, William R. Heath and Francis R. Carbone

J Immunol August 1, 2006, 177 (3) 1411-1415; DOI: https://doi.org/10.4049/jimmunol.177.3.1411
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Cutting Edge: IFN-γ Regulates the Induction and Expansion of IL-17-Producing CD4 T Cells during Mycobacterial Infection
Andrea Cruz, Shabaana A. Khader, Egidio Torrado, Alexandra Fraga, John E. Pearl, Jorge Pedrosa, Andrea M. Cooper and António G. Castro

J Immunol August 1, 2006, 177 (3) 1416-1420; DOI: https://doi.org/10.4049/jimmunol.177.3.1416
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Cutting Edge: Unique T Cells That Recognize Citrullinated Peptides Are a Feature of Protein Immunization
Jamie Ireland, Jeremy Herzog and Emil R. Unanue

J Immunol August 1, 2006, 177 (3) 1421-1425; DOI: https://doi.org/10.4049/jimmunol.177.3.1421

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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EBV-Specific CD4⁺ T Cell Clones Exhibit Vigorous Allogeneic Responses
Elise Landais, Alexis Morice, Heather M. Long, Tracey A. Haigh, Béatrice Charreau, Marc Bonneville, Graham S. Taylor and Elisabeth Houssaint

J Immunol August 1, 2006, 177 (3) 1427-1433; DOI: https://doi.org/10.4049/jimmunol.177.3.1427
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Tripeptidyl Peptidase II Is the Major Peptidase Needed to Trim Long Antigenic Precursors, but Is Not Required for Most MHC Class I Antigen Presentation
Ian A. York, Nidhi Bhutani, Sophia Zendzian, Alfred L. Goldberg and Kenneth L. Rock

J Immunol August 1, 2006, 177 (3) 1434-1443; DOI: https://doi.org/10.4049/jimmunol.177.3.1434
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Reconstitution of Allogeneic Hemopoietic Stem Cells: The Essential Role of FcRγ and the TCR β-Chain-FCp33 Complex
Kendra N. Taylor, Vivek R. Shinde Patil and Yolonda L. Colson

J Immunol August 1, 2006, 177 (3) 1444-1450; DOI: https://doi.org/10.4049/jimmunol.177.3.1444
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Suppression of Disease in New Zealand Black/New Zealand White Lupus-Prone Mice by Adoptive Transfer of Ex Vivo Expanded Regulatory T Cells
Kenneth J. Scalapino, Qizhi Tang, Jeffrey A. Bluestone, Mark L. Bonyhadi and David I. Daikh

J Immunol August 1, 2006, 177 (3) 1451-1459; DOI: https://doi.org/10.4049/jimmunol.177.3.1451
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Dendritic Cells Can Turn CD4⁺ T Lymphocytes into Vascular Endothelial Growth Factor-Carrying Cells by Intercellular Neuropilin-1 Transfer
Sarah Bourbié-Vaudaine, Nicolas Blanchard, Claire Hivroz and Paul-Henri Roméo

J Immunol August 1, 2006, 177 (3) 1460-1469; DOI: https://doi.org/10.4049/jimmunol.177.3.1460
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RasGRP1 Transmits Prodifferentiation TCR Signaling That Is Crucial for CD4 T Cell Development
John J. Priatel, Xiaoxi Chen, Salim Dhanji, Ninan Abraham and Hung-Sia Teh

J Immunol August 1, 2006, 177 (3) 1470-1480; DOI: https://doi.org/10.4049/jimmunol.177.3.1470
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The Cytoplasmic Domain of Fas Ligand Costimulates TCR Signals
Mingyi Sun, Kristina T. Ames, Ivy Suzuki and Pamela J. Fink

J Immunol August 1, 2006, 177 (3) 1481-1491; DOI: https://doi.org/10.4049/jimmunol.177.3.1481
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Phosphorylation of Nonmuscle Myosin Heavy Chain IIA on Ser¹⁹¹⁷ Is Mediated by Protein Kinase CβII and Coincides with the Onset of Stimulated Degranulation of RBL-2H3 Mast Cells
Russell I. Ludowyke, Zehra Elgundi, Tanya Kranenburg, Justine R. Stehn, Carsten Schmitz-Peiffer, William E. Hughes and Trevor J. Biden

J Immunol August 1, 2006, 177 (3) 1492-1499; DOI: https://doi.org/10.4049/jimmunol.177.3.1492
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The Thymus Plays a Role in Oral Tolerance in Experimental Autoimmune Encephalomyelitis
Fei Song, Zhen Guan, Ingrid E. Gienapp, Todd Shawler, Jacqueline Benson and Caroline C. Whitacre

J Immunol August 1, 2006, 177 (3) 1500-1509; DOI: https://doi.org/10.4049/jimmunol.177.3.1500
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Involvement of NFAT1 in B Cell Self-Tolerance
Robert A. Barrington, Madhuri Borde, Anjana Rao and Michael C. Carroll

J Immunol August 1, 2006, 177 (3) 1510-1515; DOI: https://doi.org/10.4049/jimmunol.177.3.1510
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Delayed Expansion and Contraction of CD8⁺ T Cell Response during Infection with Virulent Salmonella typhimurium
Rachel A. Luu, Komal Gurnani, Renu Dudani, Rajagopal Kammara, Henk van Faassen, Jean-Claude Sirard, Lakshmi Krishnan and Subash Sad

J Immunol August 1, 2006, 177 (3) 1516-1525; DOI: https://doi.org/10.4049/jimmunol.177.3.1516
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Immunoediting of Cancers May Lead to Epithelial to Mesenchymal Transition
Keith L. Knutson, Hailing Lu, Brad Stone, Jennifer M. Reiman, Marshall D. Behrens, Christine M. Prosperi, Ekram A. Gad, Arianna Smorlesi and Mary L. Disis

J Immunol August 1, 2006, 177 (3) 1526-1533; DOI: https://doi.org/10.4049/jimmunol.177.3.1526
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Priming Protective CD8 T Cell Immunity by DNA Vaccines Encoding Chimeric, Stress Protein-Capturing Tumor-Associated Antigen
Reinhold Schirmbeck, Petra Riedl, Mark Kupferschmitt, Ursula Wegenka, Hansjörg Hauser, Jason Rice, Andrea Kröger and Jörg Reimann

J Immunol August 1, 2006, 177 (3) 1534-1542; DOI: https://doi.org/10.4049/jimmunol.177.3.1534
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Extracellular Targeting of Endoplasmic Reticulum Chaperone Glucose-Regulated Protein 170 Enhances Tumor Immunity to a Poorly Immunogenic Melanoma
Xiang-Yang Wang, Hilal Arnouk, Xing Chen, Latif Kazim, Elizabeth A. Repasky and John R. Subjeck

J Immunol August 1, 2006, 177 (3) 1543-1551; DOI: https://doi.org/10.4049/jimmunol.177.3.1543
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Pertussis Toxin Reduces the Number of Splenic Foxp3⁺ Regulatory T Cells
Cécile Cassan, Eliane Piaggio, Jacques P. Zappulla, Lennart T. Mars, Nicolas Couturier, Florence Bucciarelli, Sabine Desbois, Jan Bauer, Daniel Gonzalez-Dunia and Roland S. Liblau

J Immunol August 1, 2006, 177 (3) 1552-1560; DOI: https://doi.org/10.4049/jimmunol.177.3.1552
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Differential Polarization of Immune Responses by Plant 2S Seed Albumins, Ber e 1, and SFA8
Dorothy E. Kean, Helen S. Goodridge, Stephen McGuinness, Margaret M. Harnett, Marcos J. C. Alcocer and William Harnett

J Immunol August 1, 2006, 177 (3) 1561-1566; DOI: https://doi.org/10.4049/jimmunol.177.3.1561
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A Critical Role for Prostaglandin E₂ in Podosome Dissolution and Induction of High-Speed Migration during Dendritic Cell Maturation
Suzanne F. G. van Helden, Daniëlle J. E. B. Krooshoop, Karin C. M. Broers, Reinier A. P. Raymakers, Carl G. Figdor and Frank N. van Leeuwen

J Immunol August 1, 2006, 177 (3) 1567-1574; DOI: https://doi.org/10.4049/jimmunol.177.3.1567
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CXCL16 Influences the Nature and Specificity of CpG-Induced Immune Activation
Mayda Gursel, Ihsan Gursel, Howard S. Mostowski and Dennis M. Klinman

J Immunol August 1, 2006, 177 (3) 1575-1580; DOI: https://doi.org/10.4049/jimmunol.177.3.1575
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Kinetics of B Cell Receptor Signaling in Human B Cell Subsets Mapped by Phosphospecific Flow Cytometry
Jonathan M. Irish, Debra K. Czerwinski, Garry P. Nolan and Ronald Levy

J Immunol August 1, 2006, 177 (3) 1581-1589; DOI: https://doi.org/10.4049/jimmunol.177.3.1581
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CD8αα-Mediated Intraepithelial Lymphocyte Snatching of Thymic Leukemia MHC Class Ib Molecules In Vitro and In Vivo
Nathalie Pardigon, Kazuyo Takeda, Bertrand Saunier, Felicita Hornung, James Gibbs, Andrea Weisberg, Nikhat Contractor, Brian Kelsall, Jack R. Bennink and Jonathan W. Yewdell

J Immunol August 1, 2006, 177 (3) 1590-1598; DOI: https://doi.org/10.4049/jimmunol.177.3.1590
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Accumulation of Immunosuppressive CD11b⁺ Myeloid Cells Correlates with the Failure to Prevent Tumor Growth in the Anterior Chamber of the Eye
Kyle C. McKenna and Judith A. Kapp

J Immunol August 1, 2006, 177 (3) 1599-1608; DOI: https://doi.org/10.4049/jimmunol.177.3.1599
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Crucial Commitment of Proteolytic Activity of a Purified Recombinant Major House Dust Mite Allergen Der p1 to Sensitization toward IgE and IgG Responses
Yuko Kikuchi, Toshiro Takai, Takatoshi Kuhara, Mikiko Ota, Takeshi Kato, Hideki Hatanaka, Saori Ichikawa, Tomoko Tokura, Hisaya Akiba, Kouichi Mitsuishi, Shigaku Ikeda, Ko Okumura and Hideoki Ogawa

J Immunol August 1, 2006, 177 (3) 1609-1617; DOI: https://doi.org/10.4049/jimmunol.177.3.1609
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Visualization of IL-12/23p40 In Vivo Reveals Immunostimulatory Dendritic Cell Migrants that Promote Th1 Differentiation
R. Lee Reinhardt, Seokmann Hong, Suk-Jo Kang, Zhi-en Wang and Richard M. Locksley

J Immunol August 1, 2006, 177 (3) 1618-1627; DOI: https://doi.org/10.4049/jimmunol.177.3.1618
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Intestinal Helminths Protect in a Murine Model of Asthma
Kunihiko Kitagaki, Thomas R. Businga, Doina Racila, David E. Elliott, Joel V. Weinstock and Joel N. Kline

J Immunol August 1, 2006, 177 (3) 1628-1635; DOI: https://doi.org/10.4049/jimmunol.177.3.1628
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Active ERK Contributes to Protein Translation by Preventing JNK-Dependent Inhibition of Protein Phosphatase 1
Martha M. Monick, Linda S. Powers, Thomas J. Gross, Dawn M. Flaherty, Christopher W. Barrett and Gary W. Hunninghake

J Immunol August 1, 2006, 177 (3) 1636-1645; DOI: https://doi.org/10.4049/jimmunol.177.3.1636
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Genetic Dissection of the Effects of Stimulatory and Inhibitory IgG Fc Receptors on Murine Lupus
Qingshun Lin, Yan Xiu, Yi Jiang, Hiromichi Tsurui, Kazuhiro Nakamura, Sanki Kodera, Mareki Ohtsuji, Naomi Ohtsuji, Wakana Shiroiwa, Kazuyuki Tsukamoto, Hirofumi Amano, Eri Amano, Katsuyuki Kinoshita, Katsuko Sudo, Hiroyuki Nishimura, Shozo Izui, Toshikazu Shirai and Sachiko Hirose

J Immunol August 1, 2006, 177 (3) 1646-1654; DOI: https://doi.org/10.4049/jimmunol.177.3.1646
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Anti-Mitochondrial Antibodies and Primary Biliary Cirrhosis in TGF-β Receptor II Dominant-Negative Mice
Sabine Oertelt, Zhe-Xiong Lian, Chun-Mei Cheng, Ya-Hui Chuang, Kerstien A. Padgett, Xiao-Song He, William M. Ridgway, Aftab A. Ansari, Ross L. Coppel, Ming O. Li, Richard A. Flavell, Mitchell Kronenberg, Ian R. Mackay and M. Eric Gershwin

J Immunol August 1, 2006, 177 (3) 1655-1660; DOI: https://doi.org/10.4049/jimmunol.177.3.1655
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Yeast β-Glucan Amplifies Phagocyte Killing of iC3b-Opsonized Tumor Cells via Complement Receptor 3-Syk-Phosphatidylinositol 3-Kinase Pathway
Bing Li, Daniel J. Allendorf, Richard Hansen, Jose Marroquin, Chuanlin Ding, Daniel E. Cramer and Jun Yan

J Immunol August 1, 2006, 177 (3) 1661-1669; DOI: https://doi.org/10.4049/jimmunol.177.3.1661
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New Generation Vaccine Induces Effective Melanoma-Specific CD8⁺ T Cells in the Circulation but Not in the Tumor Site
Victor Appay, Camilla Jandus, Verena Voelter, Severine Reynard, Sarah E. Coupland, Donata Rimoldi, Danielle Lienard, Philippe Guillaume, Arthur M. Krieg, Jean-Charles Cerottini, Pedro Romero, Serge Leyvraz, Nathalie Rufer and Daniel E. Speiser

J Immunol August 1, 2006, 177 (3) 1670-1678; DOI: https://doi.org/10.4049/jimmunol.177.3.1670
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Dendritic Cells Transduced with SOCS-3 Exhibit a Tolerogenic/DC2 Phenotype That Directs Type 2 Th Cell Differentiation In Vitro and In Vivo
Yonghai Li, Niansheng Chu, Abdolmohamad Rostami and Guang-Xian Zhang

J Immunol August 1, 2006, 177 (3) 1679-1688; DOI: https://doi.org/10.4049/jimmunol.177.3.1679
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Local Intrahepatic CD8⁺ T Cell Activation by a Non-Self- Antigen Results in Full Functional Differentiation
Sherry A. Wuensch, Robert H. Pierce and I. Nicholas Crispe

J Immunol August 1, 2006, 177 (3) 1689-1697; DOI: https://doi.org/10.4049/jimmunol.177.3.1689

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Autoimmunity as a Result of Escape from RNA Surveillance
Michael P. Bachmann, Holger Bartsch, Joanne K. Gross, Shannon M. Maier, Timothy F. Gross, Jennifer L. Workman, Judith A. James, A. Darise Farris, Bettina Jung, Claudia Franke, Karsten Conrad, Marc Schmitz, Cordula Büttner, Jill P. Buyon, Imre Semsei, John B. Harley and E. Peter Rieber

J Immunol August 1, 2006, 177 (3) 1698-1707; DOI: https://doi.org/10.4049/jimmunol.177.3.1698
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Specific Patterns of Cdc42 Activity Are Related to Distinct Elements of T Cell Polarization
Irina Tskvitaria-Fuller, Abhinav Seth, Neeta Mistry, Hua Gu, Michael K. Rosen and Christoph Wülfing

J Immunol August 1, 2006, 177 (3) 1708-1720; DOI: https://doi.org/10.4049/jimmunol.177.3.1708
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Filamin A Is Required for T Cell Activation Mediated by Protein Kinase C-θ
Keitaro Hayashi and Amnon Altman

J Immunol August 1, 2006, 177 (3) 1721-1728; DOI: https://doi.org/10.4049/jimmunol.177.3.1721
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Arginine Residues Are Important in Determining the Binding of Human Monoclonal Antiphospholipid Antibodies to Clinically Relevant Antigens
Ian Giles, Nancy Lambrianides, Nisha Pattni, David Faulkes, David Latchman, Pojen Chen, Silvia Pierangeli, David Isenberg and Anisur Rahman

J Immunol August 1, 2006, 177 (3) 1729-1736; DOI: https://doi.org/10.4049/jimmunol.177.3.1729
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Degalactosylated and/or Denatured IgA, but Not Native IgA in Any Form, Bind to Mannose-Binding Lectin
Itaru Terai, Kunihiko Kobayashi, Jean-Pierre Vaerman and Naoki Mafune

J Immunol August 1, 2006, 177 (3) 1737-1745; DOI: https://doi.org/10.4049/jimmunol.177.3.1737

HOST DEFENSE

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Innate Inflammatory Signals Induced by Various Pathogens Differentially Dictate the IFN-I Dependence of CD8 T Cells for Clonal Expansion and Memory Formation
Lucas J. Thompson, Ganesh A. Kolumam, Sunil Thomas and Kaja Murali-Krishna

J Immunol August 1, 2006, 177 (3) 1746-1754; DOI: https://doi.org/10.4049/jimmunol.177.3.1746
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Mast Cells Have a Pivotal Role in TNF-Independent Lymph Node Hypertrophy and the Mobilization of Langerhans Cells in Response to Bacterial Peptidoglycan
Dunia M. Jawdat, Geoffrey Rowden and Jean S. Marshall

J Immunol August 1, 2006, 177 (3) 1755-1762; DOI: https://doi.org/10.4049/jimmunol.177.3.1755
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B Cells and CD4⁻CD8⁻ T Cells Are Key Regulators of the Severity of Reactivation Histoplasmosis
Holly L. Allen and George S. Deepe Jr.

J Immunol August 1, 2006, 177 (3) 1763-1771; DOI: https://doi.org/10.4049/jimmunol.177.3.1763
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A Protein Associated with Toll-Like Receptor 4 (PRAT4A) Regulates Cell Surface Expression of TLR4
Yasutaka Wakabayashi, Makiko Kobayashi, Sachiko Akashi-Takamura, Natsuko Tanimura, Kazunori Konno, Koichiro Takahashi, Takashi Ishii, Taketoshi Mizutani, Hideo Iba, Taku Kouro, Satoshi Takaki, Kiyoshi Takatsu, Yoshiya Oda, Yasushi Ishihama, Shin-ichiroh Saitoh and Kensuke Miyake

J Immunol August 1, 2006, 177 (3) 1772-1779; DOI: https://doi.org/10.4049/jimmunol.177.3.1772
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Phenotypical and Functional Analysis of Memory and Effector Human CD8 T Cells Specific for Mycobacterial Antigens
Nadia Caccamo, Serena Meraviglia, Carmela La Mendola, Giuliana Guggino, Francesco Dieli and Alfredo Salerno

J Immunol August 1, 2006, 177 (3) 1780-1785; DOI: https://doi.org/10.4049/jimmunol.177.3.1780
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T-bet Deficiency Facilitates Airway Colonization by Mycoplasma pulmonis in a Murine Model of Asthma
Chandra Shekhar Bakshi, Meenakshi Malik, Pauline M. Carrico and Timothy J. Sellati

J Immunol August 1, 2006, 177 (3) 1786-1795; DOI: https://doi.org/10.4049/jimmunol.177.3.1786
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Meso-Diaminopimelic Acid and Meso-Lanthionine, Amino Acids Specific to Bacterial Peptidoglycans, Activate Human Epithelial Cells through NOD1
Akiko Uehara, Yukari Fujimoto, Akiko Kawasaki, Shoichi Kusumoto, Koichi Fukase and Haruhiko Takada

J Immunol August 1, 2006, 177 (3) 1796-1804; DOI: https://doi.org/10.4049/jimmunol.177.3.1796
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Fine Discrimination in the Recognition of Individual Species of Phosphatidyl-myo-Inositol Mannosides from Mycobacterium tuberculosis by C-Type Lectin Pattern Recognition Receptors
Jordi B. Torrelles, Abul K. Azad and Larry S. Schlesinger

J Immunol August 1, 2006, 177 (3) 1805-1816; DOI: https://doi.org/10.4049/jimmunol.177.3.1805
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Alveolar Epithelial Cells Direct Monocyte Transepithelial Migration upon Influenza Virus Infection: Impact of Chemokines and Adhesion Molecules
Susanne Herold, Werner von Wulffen, Mirko Steinmueller, Stephan Pleschka, William A. Kuziel, Matthias Mack, Mrigank Srivastava, Werner Seeger, Ulrich A. Maus and Juergen Lohmeyer

J Immunol August 1, 2006, 177 (3) 1817-1824; DOI: https://doi.org/10.4049/jimmunol.177.3.1817
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γδ T Cells Facilitate Adaptive Immunity against West Nile Virus Infection in Mice
Tian Wang, Yunfei Gao, Eileen Scully, C. Todd Davis, John F. Anderson, Thomas Welte, Michel Ledizet, Raymond Koski, Joseph A. Madri, Alan Barrett, Zhinan Yin, Joseph Craft and Erol Fikrig

J Immunol August 1, 2006, 177 (3) 1825-1832; DOI: https://doi.org/10.4049/jimmunol.177.3.1825
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Allergic Airway Inflammation Inhibits Pulmonary Antibacterial Host Defense
Christoph Beisswenger, Kerstin Kandler, Christian Hess, Holger Garn, Kerstin Felgentreff, Michael Wegmann, Harald Renz, Claus Vogelmeier and Robert Bals

J Immunol August 1, 2006, 177 (3) 1833-1837; DOI: https://doi.org/10.4049/jimmunol.177.3.1833
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A Novel 40-kDa Protein Containing Six Repeats of an Epidermal Growth Factor-Like Domain Functions as a Pattern Recognition Protein for Lipopolysaccharide
Jin Sung Ju, Mi Hyang Cho, Lore Brade, Jung Hyun Kim, Ji Won Park, Nam-Chul Ha, Irene Söderhäll, Kenneth Söderhäll, Helmut Brade and Bok Luel Lee

J Immunol August 1, 2006, 177 (3) 1838-1845; DOI: https://doi.org/10.4049/jimmunol.177.3.1838
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CXCR3 and IFN Protein-10 in Pneumocystis Pneumonia
Florencia McAllister, Sanbao Ruan, Chad Steele, Mingquan Zheng, Laura McKinley, Lauren Ulrich, Luis Marrero, Judd E. Shellito and Jay K. Kolls

J Immunol August 1, 2006, 177 (3) 1846-1854; DOI: https://doi.org/10.4049/jimmunol.177.3.1846
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Both CXCR3 and CXCL10/IFN-Inducible Protein 10 Are Required for Resistance to Primary Infection by Dengue Virus
Ming-Fang Hsieh, Szu-Liang Lai, Jia-Perng Chen, Jui-Ming Sung, Yi-Ling Lin, Betty A. Wu-Hsieh, Craig Gerard, Andrew Luster and Fang Liao

J Immunol August 1, 2006, 177 (3) 1855-1863; DOI: https://doi.org/10.4049/jimmunol.177.3.1855
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Macrophages Acquire Neutrophil Granules for Antimicrobial Activity against Intracellular Pathogens
Belinda H. Tan, Christoph Meinken, Max Bastian, Heiko Bruns, Annaliza Legaspi, Maria Teresa Ochoa, Stephan R. Krutzik, Barry R. Bloom, Tomas Ganz, Robert L. Modlin and Steffen Stenger

J Immunol August 1, 2006, 177 (3) 1864-1871; DOI: https://doi.org/10.4049/jimmunol.177.3.1864

INFLAMMATION

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Complement Activation via Alternative Pathway Is Critical in the Development of Laser-Induced Choroidal Neovascularization: Role of Factor B and Factor H
Nalini S. Bora, Sankaranarayanan Kaliappan, Purushottam Jha, Qin Xu, Jeong-Hyeon Sohn, Dhara B. Dhaulakhandi, Henry J. Kaplan and Puran S. Bora

J Immunol August 1, 2006, 177 (3) 1872-1878; DOI: https://doi.org/10.4049/jimmunol.177.3.1872
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Membrane-Bound Prostaglandin E Synthase-1-Mediated Prostaglandin E₂ Production by Osteoblast Plays a Critical Role in Lipopolysaccharide-Induced Bone Loss Associated with Inflammation
Masaki Inada, Chiho Matsumoto, Satoshi Uematsu, Shizuo Akira and Chisato Miyaura

J Immunol August 1, 2006, 177 (3) 1879-1885; DOI: https://doi.org/10.4049/jimmunol.177.3.1879
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PKC-θ-Deficient Mice Are Protected from Th1-Dependent Antigen-Induced Arthritis
Aileen M. Healy, Elena Izmailova, Michael Fitzgerald, Russell Walker, Maureen Hattersley, Matthew Silva, Elizabeth Siebert, Jennifer Terkelsen, Dominic Picarella, Michael D. Pickard, Brett LeClair, Sudeep Chandra and Bruce Jaffee

J Immunol August 1, 2006, 177 (3) 1886-1893; DOI: https://doi.org/10.4049/jimmunol.177.3.1886
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The Antiapoptotic Effect of Heme Oxygenase-1 in Endothelial Cells Involves the Degradation of p38α MAPK Isoform
Gabriela Silva, Andreia Cunha, Isabel Pombo Grégoire, Mark P. Seldon and Miguel P. Soares

J Immunol August 1, 2006, 177 (3) 1894-1903; DOI: https://doi.org/10.4049/jimmunol.177.3.1894
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Alternative Complement Pathway Activation Is Essential for Inflammation and Joint Destruction in the Passive Transfer Model of Collagen-Induced Arthritis
Nirmal K. Banda, Joshua M. Thurman, Damian Kraus, Allyson Wood, Michael C. Carroll, William P. Arend and V. Michael Holers

J Immunol August 1, 2006, 177 (3) 1904-1912; DOI: https://doi.org/10.4049/jimmunol.177.3.1904
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MAPKAP Kinase 2-Deficient Mice Are Resistant to Collagen-Induced Arthritis
Martin Hegen, Matthias Gaestel, Cheryl L. Nickerson-Nutter, Lih-Ling Lin and Jean-Baptiste Telliez

J Immunol August 1, 2006, 177 (3) 1913-1917; DOI: https://doi.org/10.4049/jimmunol.177.3.1913
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Role of 5-Lipoxygenase in IL-13-Induced Pulmonary Inflammation and Remodeling
Yun M. Shim, Zhou Zhu, Tao Zheng, Chun G. Lee, Robert J. Homer, Bing Ma and Jack A. Elias

J Immunol August 1, 2006, 177 (3) 1918-1924; DOI: https://doi.org/10.4049/jimmunol.177.3.1918
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TLR2 Stimulation of Intrinsic Renal Cells in the Induction of Immune-Mediated Glomerulonephritis
Heather J. Brown, Helen R. Lock, Steven H. Sacks and Michael G. Robson

J Immunol August 1, 2006, 177 (3) 1925-1931; DOI: https://doi.org/10.4049/jimmunol.177.3.1925
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Expression of CD44 and L-Selectin in the Innate Immune System Is Required for Severe Joint Inflammation in the Proteoglycan-Induced Murine Model of Rheumatoid Arthritis
Bara Sarraj, Katalin Ludányi, Tibor T. Glant, Alison Finnegan and Katalin Mikecz

J Immunol August 1, 2006, 177 (3) 1932-1940; DOI: https://doi.org/10.4049/jimmunol.177.3.1932
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Hypoxia Modifies the Transcriptome of Primary Human Monocytes: Modulation of Novel Immune-Related Genes and Identification Of CC-Chemokine Ligand 20 as a New Hypoxia-Inducible Gene
Maria Carla Bosco, Maura Puppo, Clara Santangelo, Luca Anfosso, Ulrich Pfeffer, Paolo Fardin, Florinda Battaglia and Luigi Varesio

J Immunol August 1, 2006, 177 (3) 1941-1955; DOI: https://doi.org/10.4049/jimmunol.177.3.1941
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The Adenosine System Selectively Inhibits TLR-Mediated TNF-α Production in the Human Newborn
Ofer Levy, Melissa Coughlin, Bruce N. Cronstein, Rene M. Roy, Avani Desai and Michael R. Wessels

J Immunol August 1, 2006, 177 (3) 1956-1966; DOI: https://doi.org/10.4049/jimmunol.177.3.1956
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Circulating Cytokine/Inhibitor Profiles Reshape the Understanding of the SIRS/CARS Continuum in Sepsis and Predict Mortality
Marcin F. Osuchowski, Kathy Welch, Javed Siddiqui and Daniel G. Remick

J Immunol August 1, 2006, 177 (3) 1967-1974; DOI: https://doi.org/10.4049/jimmunol.177.3.1967
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Monocyte/Macrophage-Derived Microparticles Up-Regulate Inflammatory Mediator Synthesis by Human Airway Epithelial Cells
Chiara Cerri, Daniele Chimenti, Ilaria Conti, Tommaso Neri, Pierluigi Paggiaro and Alessandro Celi

J Immunol August 1, 2006, 177 (3) 1975-1980; DOI: https://doi.org/10.4049/jimmunol.177.3.1975

CLINICAL IMMUNOLOGY

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Induction of Cytotoxic Granules in Human Memory CD8⁺ T Cell Subsets Requires Cell Cycle Progression
Yuru Meng, Helena Harlin, James P. O’Keefe and Thomas F. Gajewski

J Immunol August 1, 2006, 177 (3) 1981-1987; DOI: https://doi.org/10.4049/jimmunol.177.3.1981
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Autoimmune Targeted Disruption of the Pituitary-Ovarian Axis Causes Premature Ovarian Failure
Cengiz Z. Altuntas, Justin M. Johnson and Vincent K. Tuohy

J Immunol August 1, 2006, 177 (3) 1988-1996; DOI: https://doi.org/10.4049/jimmunol.177.3.1988
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Translationally Controlled Tumor Protein from Madurella mycetomatis, a Marker for Tumorous Mycetoma Progression
Wendy W. J. van de Sande, Dirk-Jan Janse, Vishal Hira, Heidy Goedhart, Ruurd van der Zee, Abdalla O. A. Ahmed, Alewijn Ott, Henri Verbrugh and Alex van Belkum

J Immunol August 1, 2006, 177 (3) 1997-2005; DOI: https://doi.org/10.4049/jimmunol.177.3.1997
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Complex T Cell Memory Repertoires Participate in Recall Responses at Extremes of Antigenic Load
Yuri N. Naumov, Elena N. Naumova, Shalyn C. Clute, Levi B. Watkin, Kalyani Kota, Jack Gorski and Liisa K. Selin

J Immunol August 1, 2006, 177 (3) 2006-2014; DOI: https://doi.org/10.4049/jimmunol.177.3.2006
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Reduced Peripheral and Mucosal Tropheryma whipplei-Specific Th1 Response in Patients with Whipple’s Disease
Verena Moos, Désirée Kunkel, Thomas Marth, Gerhard E. Feurle, Bernard LaScola, Ralf Ignatius, Martin Zeitz and Thomas Schneider

J Immunol August 1, 2006, 177 (3) 2015-2022; DOI: https://doi.org/10.4049/jimmunol.177.3.2015

LETTER OF RETRACTION

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Retraction: Elevated T Regulatory Cells in Long-Term Stable Transplant Tolerance in Rhesus Macaques Induced by Anti-CD3 Immunot oxin and Deoxyspergualin
Clement K. Asiedu, Karen J. Goodwin, Gansuvd Balgansuren, Stacie M. Jenkins, Stéphanie Le Bas-Bernardet, Uuganbayar Jargal, Judith M. Thomas and David M. Neville Jr.

J Immunol August 1, 2006, 177 (3) 2023; DOI: https://doi.org/10.4049/jimmunol.177.3.2023

CORRECTIONS

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Neonatally primed lymph node, but not splenic T cells, display a Gly-Gly motif within the TCR β-chain complementarity-determining region 3 that controls affinity and may affect lymphoid organ retention.
J. C. Caprio-Young, J. J. Bell, H.-H. Lee, J. Ellis, D. Nast, G. Sayler, B. Min and H. Zaghouani

J Immunol August 1, 2006, 177 (3) 2024; DOI: https://doi.org/10.4049/jimmunol.177.3.2024
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Chemoimmunotherapy of tumors: cyclophosphamide synergizes with exosome based vaccines.
J. Taieb, N. Chaput, N. Schartz, S. Roux, S. Novault, C. Ménard, F. Ghiringhelli, M. Terme, A. F. Carpentier, G. Darrasse-Jèse, F. Lemonnier and L. Zitvogel

J Immunol August 1, 2006, 177 (3) 2024; DOI: https://doi.org/10.4049/jimmunol.177.3.2024-a
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Monoclonal antibodies for Bacillus anthracis spore detection and functional analyses of spore germination and outgrowth.
M. K. Swiecki, M. W. Lisanby, F. Shu, C. L. Turnbough Jr. and J. F. Kearney

J Immunol August 1, 2006, 177 (3) 2024; DOI: https://doi.org/10.4049/jimmunol.177.3.2024-b
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Involvement of CCL18 in allergic asthma.
P. de Nadaï, A.-S. Charbonnier, C. Chenivesse, S. Sénéchal, C. Fournier, J. Gilet, H. Vorng, Y. Chang, P. Gosset, B. Wallaert, A.-B. Tonnel, P. Lassalle and A. Tsicopoulos

J Immunol August 1, 2006, 177 (3) 2025; DOI: https://doi.org/10.4049/jimmunol.177.3.2025
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A membrane form of TNFα presented by exosomes delays T cell activation-induced cell death.
H.-G. Zhang, C. Liu, K. Su, S. Yu, L. Zhang, S. Zhang, J. Wang, X. Cao, W. Grizzle and R. P. Kimberly

J Immunol August 1, 2006, 177 (3) 2025; DOI: https://doi.org/10.4049/jimmunol.177.3.2025-a
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IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production.
A. Vaknin-Dembinsky, K. Balashov and H. L. Weiner

J Immunol August 1, 2006, 177 (3) 2025; DOI: https://doi.org/10.4049/jimmunol.177.3.2025-b

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Table of Contents

PRESIDENTIAL ADDRESS

IN THIS ISSUE

LETTERS TO THE EDITOR

PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

LETTER OF RETRACTION

CORRECTIONS

This Issue

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