Table of Contents

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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  Limited Infiltration of Exogenous Dendritic Cells and Naive T Cells Restricts Immune Responses in Peripheral Lymph Nodes

  David W. Mullins and Victor H. Engelhard

  J Immunol April 15, 2006, 176 (8) 4535-4542; DOI: https://doi.org/10.4049/jimmunol.176.8.4535
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  Bruton’s Tyrosine Kinase and SLP-65 Regulate Pre-B Cell Differentiation and the Induction of Ig Light Chain Gene Rearrangement

  Rogier Kersseboom, Van B. T. Ta, A. J. Esther Zijlstra, Sabine Middendorp, Hassan Jumaa, Pieter Fokko van Loo and Rudolf W. Hendriks

  J Immunol April 15, 2006, 176 (8) 4543-4552; DOI: https://doi.org/10.4049/jimmunol.176.8.4543
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  Antigen Challenge Inhibits Thymic Emigration

  Adam P. Uldrich, Stuart P. Berzins, Mark A. Malin, Philippe Bouillet, Andreas Strasser, Mark J. Smyth, Richard L. Boyd and Dale I. Godfrey

  J Immunol April 15, 2006, 176 (8) 4553-4561; DOI: https://doi.org/10.4049/jimmunol.176.8.4553
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  DNA Methylation by DNA Methyltransferase 1 Is Critical for Effector CD8 T Cell Expansion

  Craig Chappell, Caroline Beard, John Altman, Rudolph Jaenisch and Joshy Jacob

  J Immunol April 15, 2006, 176 (8) 4562-4572; DOI: https://doi.org/10.4049/jimmunol.176.8.4562
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  Immune Complex-Loaded Dendritic Cells Are Superior to Soluble Immune Complexes as Antitumor Vaccine

  Danita H. Schuurhuis, Nadine van Montfoort, Andreea Ioan-Facsinay, Reshma Jiawan, Marcel Camps, Jan Nouta, Cornelis J. M. Melief, J. Sjef Verbeek and Ferry Ossendorp

  J Immunol April 15, 2006, 176 (8) 4573-4580; DOI: https://doi.org/10.4049/jimmunol.176.8.4573
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  Oral Nickel Tolerance: Fas Ligand-Expressing Invariant NK T Cells Promote Tolerance Induction by Eliciting Apoptotic Death of Antigen-Carrying, Effete B Cells

  Michael Nowak, Frank Kopp, Karin Roelofs-Haarhuis, Xianzhu Wu and Ernst Gleichmann

  J Immunol April 15, 2006, 176 (8) 4581-4589; DOI: https://doi.org/10.4049/jimmunol.176.8.4581
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  Targeted Disruption of CD38 Accelerates Autoimmune Diabetes in NOD/Lt Mice by Enhancing Autoimmunity in an ADP-Ribosyltransferase 2-Dependent Fashion

  Jing Chen, Yi-Guang Chen, Peter C. Reifsnyder, William H. Schott, Chul-Ho Lee, Melissa Osborne, Felix Scheuplein, Friedrich Haag, Friedrich Koch-Nolte, David V. Serreze and Edward H. Leiter

  J Immunol April 15, 2006, 176 (8) 4590-4599; DOI: https://doi.org/10.4049/jimmunol.176.8.4590
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  Insufficient APC Capacities of Dendritic Cells in Gene Gun-Mediated DNA Vaccination

  Henning Lauterbach, Anton Gruber, Christine Ried, Cedric Cheminay and Thomas Brocker

  J Immunol April 15, 2006, 176 (8) 4600-4607; DOI: https://doi.org/10.4049/jimmunol.176.8.4600
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  Intranasal Vaccination with Proinsulin DNA Induces Regulatory CD4⁺ T Cells That Prevent Experimental Autoimmune Diabetes

  Alison L. Every, David R. Kramer, Stuart I. Mannering, Andrew M. Lew and Leonard C. Harrison

  J Immunol April 15, 2006, 176 (8) 4608-4615; DOI: https://doi.org/10.4049/jimmunol.176.8.4608
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  Selective Requirement of p38α MAPK in Cytokine-Dependent, but Not Antigen Receptor-Dependent, Th1 Responses

  Lisa S. Berenson, Jianfei Yang, Barry P. Sleckman, Theresa L. Murphy and Kenneth M. Murphy

  J Immunol April 15, 2006, 176 (8) 4616-4621; DOI: https://doi.org/10.4049/jimmunol.176.8.4616
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  MHC Class II Expression Identifies Functionally Distinct Human Regulatory T Cells

  Clare Baecher-Allan, Elizabeth Wolf and David A. Hafler

  J Immunol April 15, 2006, 176 (8) 4622-4631; DOI: https://doi.org/10.4049/jimmunol.176.8.4622
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  Accelerated Memory Cell Homeostasis during T Cell Depletion and Approaches to Overcome It

  David C. Neujahr, Chuangqi Chen, Xiaolun Huang, James F. Markmann, Stephen Cobbold, Herman Waldmann, Mohamed H. Sayegh, Wayne W. Hancock and Laurence A. Turka

  J Immunol April 15, 2006, 176 (8) 4632-4639; DOI: https://doi.org/10.4049/jimmunol.176.8.4632
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  DOCK2 Is Required in T Cell Precursors for Development of Vα14 NK T Cells

  Yuya Kunisaki, Yoshihiko Tanaka, Terukazu Sanui, Ayumi Inayoshi, Mayuko Noda, Toshinori Nakayama, Michishige Harada, Masaru Taniguchi, Takehiko Sasazuki and Yoshinori Fukui

  J Immunol April 15, 2006, 176 (8) 4640-4645; DOI: https://doi.org/10.4049/jimmunol.176.8.4640
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  CD48 Stimulation by 2B4 (CD244)-Expressing Targets Activates Human NK Cells

  Birgitta Messmer, Philipp Eissmann, Sebastian Stark and Carsten Watzl

  J Immunol April 15, 2006, 176 (8) 4646-4650; DOI: https://doi.org/10.4049/jimmunol.176.8.4646
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  Dendritic Cell Differentiation and Immune Tolerance to Insulin-Related Peptides in Igf2-Deficient Mice

  Isabelle Hansenne, Chantal Renard-Charlet, Roland Greimers and Vincent Geenen

  J Immunol April 15, 2006, 176 (8) 4651-4657; DOI: https://doi.org/10.4049/jimmunol.176.8.4651
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  Conditioning of Langerhans Cells Induced by a Primary CD8 T Cell Response to Self-Antigen In Vivo

  Dita Mayerova, Liangchun Wang, Laura S. Bursch and Kristin A. Hogquist

  J Immunol April 15, 2006, 176 (8) 4658-4665; DOI: https://doi.org/10.4049/jimmunol.176.8.4658
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  NF-κB-Inducing Kinase Is Involved in the Activation of the CD28 Responsive Element through Phosphorylation of c-Rel and Regulation of Its Transactivating Activity

  Carmen Sánchez-Valdepeñas, Angel G. Martín, Parameswaran Ramakrishnan, David Wallach and Manuel Fresno

  J Immunol April 15, 2006, 176 (8) 4666-4674; DOI: https://doi.org/10.4049/jimmunol.176.8.4666
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  Nitric Oxide Protects Macrophages from Hydrogen Peroxide-Induced Apoptosis by Inducing the Formation of Catalase

  Yasuhiro Yoshioka, Tatsuya Kitao, Takashi Kishino, Akiko Yamamuro and Sadaaki Maeda

  J Immunol April 15, 2006, 176 (8) 4675-4681; DOI: https://doi.org/10.4049/jimmunol.176.8.4675
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  Direct Stimulation of T Cells by Type I IFN Enhances the CD8⁺ T Cell Response during Cross-Priming

  Agnes Le Bon, Vanessa Durand, Elisabeth Kamphuis, Clare Thompson, Silvia Bulfone-Paus, Cornelia Rossmann, Ulrich Kalinke and David F. Tough

  J Immunol April 15, 2006, 176 (8) 4682-4689; DOI: https://doi.org/10.4049/jimmunol.176.8.4682
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  Phospholipase Cγ2 Dosage Is Critical for B Cell Development in the Absence of Adaptor Protein BLNK

  Shengli Xu, Jianxin Huo, Weng-Keong Chew, Masaki Hikida, Tomohiro Kurosaki and Kong-Peng Lam

  J Immunol April 15, 2006, 176 (8) 4690-4698; DOI: https://doi.org/10.4049/jimmunol.176.8.4690
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  Motif Inference Reveals Optimal CTL Epitopes Presented by HLA Class I Alleles Highly Prevalent in Southern Africa

  Isobella Honeyborne, Almas Rathod, Rico Buchli, Dhanwanthie Ramduth, Eshia Moodley, Prinisha Rathnavalu, Senica Chetty, Cheryl Day, Christian Brander, William Hildebrand, Bruce D. Walker, Photini Kiepiela and Philip J. R. Goulder

  J Immunol April 15, 2006, 176 (8) 4699-4705; DOI: https://doi.org/10.4049/jimmunol.176.8.4699
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  Identification of Memory B Cells Using a Novel Transgenic Mouse Model

  Craig P. Chappell and Joshy Jacob

  J Immunol April 15, 2006, 176 (8) 4706-4715; DOI: https://doi.org/10.4049/jimmunol.176.8.4706
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  IFN-γ Acts on T Cells to Induce NK Cell Mobilization and Accumulation in Target Organs

  Ori Wald, Ido D. Weiss, Hanna Wald, Hadas Shoham, Yochay Bar-Shavit, Katia Beider, Eithan Galun, Lola Weiss, Liat Flaishon, Idit Shachar, Arnon Nagler, Bao Lu, Craig Gerard, Ji-Liang Gao, Eyal Mishani, Joshua Farber and Amnon Peled

  J Immunol April 15, 2006, 176 (8) 4716-4729; DOI: https://doi.org/10.4049/jimmunol.176.8.4716
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  Adaptive Islet-Specific Regulatory CD4 T Cells Control Autoimmune Diabetes and Mediate the Disappearance of Pathogenic Th1 Cells In Vivo

  Sarah E. Weber, Judith Harbertson, Elana Godebu, Guthrie A. Mros, Ryan C. Padrick, Bryan D. Carson, Steven F. Ziegler and Linda M. Bradley

  J Immunol April 15, 2006, 176 (8) 4730-4739; DOI: https://doi.org/10.4049/jimmunol.176.8.4730
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  Early Growth Response Gene 1 Provides Negative Feedback to Inhibit Entry of Progenitor Cells into the Thymus

  Frederick J. Schnell, Allison L. Zoller, Seema R. Patel, Ifor R. Williams and Gilbert J. Kersh

  J Immunol April 15, 2006, 176 (8) 4740-4747; DOI: https://doi.org/10.4049/jimmunol.176.8.4740
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  Control of Autoimmune Myocarditis and Multiorgan Inflammation by Glucocorticoid-Induced TNF Receptor Family-Related Protein^high, Foxp3-Expressing CD25⁺ and CD25⁻ Regulatory T Cells

  Masahiro Ono, Jun Shimizu, Yoshiki Miyachi and Shimon Sakaguchi

  J Immunol April 15, 2006, 176 (8) 4748-4756; DOI: https://doi.org/10.4049/jimmunol.176.8.4748
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  Immunosensitization of Tumor Cells to Dendritic Cell-Activated Immune Responses with the Proteasome Inhibitor Bortezomib (PS-341, Velcade)

  Lana Y. Schumacher, Dan D. Vo, Hermes J. Garban, Begoña Comin-Anduix, Sharla K. Owens, Vivian B. Dissette, John A. Glaspy, William H. McBride, Benjamin Bonavida, James S. Economou and Antoni Ribas

  J Immunol April 15, 2006, 176 (8) 4757-4765; DOI: https://doi.org/10.4049/jimmunol.176.8.4757
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  Identification of Novel Th2-Associated Genes in T Memory Responses to Allergens

  Anthony Bosco, Kathy L. McKenna, Catherine J. Devitt, Martin J. Firth, Peter D. Sly and Patrick G. Holt

  J Immunol April 15, 2006, 176 (8) 4766-4777; DOI: https://doi.org/10.4049/jimmunol.176.8.4766
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  Engagement of CD28 Outside of the Immunological Synapse Results in Up-Regulation of IL-2 mRNA Stability but Not IL-2 Transcription

  Mariano Sanchez-Lockhart and Jim Miller

  J Immunol April 15, 2006, 176 (8) 4778-4784; DOI: https://doi.org/10.4049/jimmunol.176.8.4778
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  Selective Regulation of IL-10 Signaling and Function by Zymosan

  Zhimei Du, Erin Kelly, Ingrid Mecklenbräuker, Lucila Agle, Carmen Herrero, Paul Paik and Lionel B. Ivashkiv

  J Immunol April 15, 2006, 176 (8) 4785-4792; DOI: https://doi.org/10.4049/jimmunol.176.8.4785
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  Coordination of NF-κB and NFAT Antagonism by the Forkhead Transcription Factor Foxd1

  Ling Lin and Stanford L. Peng

  J Immunol April 15, 2006, 176 (8) 4793-4803; DOI: https://doi.org/10.4049/jimmunol.176.8.4793
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  IFN-γ Enhances Production of Nitric Oxide from Macrophages via a Mechanism That Depends on Nucleotide Oligomerization Domain-2

  Sabine Tötemeyer, Mark Sheppard, Adrian Lloyd, David Roper, Christopher Dowson, David Underhill, Peter Murray, Duncan Maskell and Clare Bryant

  J Immunol April 15, 2006, 176 (8) 4804-4810; DOI: https://doi.org/10.4049/jimmunol.176.8.4804
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  Differential T Cell-Mediated Regulation of CD23 (FcεRII) in B Cells and Follicular Dendritic Cells

  Selvakumar Sukumar, Daniel H. Conrad, Andras K. Szakal and John G. Tew

  J Immunol April 15, 2006, 176 (8) 4811-4817; DOI: https://doi.org/10.4049/jimmunol.176.8.4811
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  Wip1 Phosphatase-Deficient Mice Exhibit Defective T Cell Maturation Due To Sustained p53 Activation

  Marco L. Schito, Oleg N. Demidov, Shin’ichi Saito, Jonathan D. Ashwell and Ettore Appella

  J Immunol April 15, 2006, 176 (8) 4818-4825; DOI: https://doi.org/10.4049/jimmunol.176.8.4818
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  In Vivo Recognition of Ovalbumin Expressed by Transgenic Leishmania Is Determined by Its Subcellular Localization

  Sara Prickett, Peter M. Gray, Sara L. Colpitts, Phillip Scott, Paul M. Kaye and Deborah F. Smith

  J Immunol April 15, 2006, 176 (8) 4826-4833; DOI: https://doi.org/10.4049/jimmunol.176.8.4826