The Journal of Immunology: 176 (4)

February 15, 2006; Volume 176,Issue 4

EDITORIALS

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From Whence We Come (Happy Birthday to Us)
Robert R. Rich

J Immunol February 15, 2006, 176 (4) 2031-2032; DOI: https://doi.org/10.4049/jimmunol.176.4.2031
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90th Anniversary Article: Studies in Anaphylaxis. XIV. On the Relation between Precipitin and Sensitizin. J. Immunol. 1916. 1: 1–18.
Richard Weil

J Immunol February 15, 2006, 176 (4) 2033-2050; DOI: https://doi.org/10.4049/jimmunol.176.4.2033

IN THIS ISSUE

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IN THIS ISSUE

J Immunol February 15, 2006, 176 (4) 2051-2052; DOI: https://doi.org/10.4049/jimmunol.176.4.2051

BRIEF REVIEWS

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Experimental Models to Study Development and Function of the Human Immune System In Vivo
Nicolas Legrand, Kees Weijer and Hergen Spits

J Immunol February 15, 2006, 176 (4) 2053-2058; DOI: https://doi.org/10.4049/jimmunol.176.4.2053

CUTTING EDGE

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Cutting Edge: An Alternative Pathway of CD4⁺ T Cell Differentiation Is Induced Following Activation in the Absence of γ-Chain-Dependent Cytokine Signals
Shane R. Mayack and Leslie J. Berg

J Immunol February 15, 2006, 176 (4) 2059-2063; DOI: https://doi.org/10.4049/jimmunol.176.4.2059
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Cutting Edge: Influence of the TCR Vβ Domain on the Selection of Semi-Invariant NKT Cells by Endogenous Ligands
Jens Schümann, Marcin P. Mycko, Paolo Dellabona, Giulia Casorati and H. Robson MacDonald

J Immunol February 15, 2006, 176 (4) 2064-2068; DOI: https://doi.org/10.4049/jimmunol.176.4.2064
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Cutting Edge: Novel Human Dendritic Cell- and Monocyte-Attracting Chemokine-Like Protein Identified by Fold Recognition Methods
M. Teresa Pisabarro, Beatrice Leung, Mandy Kwong, Racquel Corpuz, Gretchen D. Frantz, Nancy Chiang, Richard Vandlen, Lauri J. Diehl, Nicholas Skelton, Hok Seon Kim, Dan Eaton and Kerstin N. Schmidt

J Immunol February 15, 2006, 176 (4) 2069-2073; DOI: https://doi.org/10.4049/jimmunol.176.4.2069
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Cutting Edge: Enhancement of Antibody Responses Through Direct Stimulation of B and T Cells by Type I IFN
Agnes Le Bon, Clare Thompson, Elisabeth Kamphuis, Vanessa Durand, Cornelia Rossmann, Ulrich Kalinke and David F. Tough

J Immunol February 15, 2006, 176 (4) 2074-2078; DOI: https://doi.org/10.4049/jimmunol.176.4.2074
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Cutting Edge: Gut Microenvironment Promotes Differentiation of a Unique Memory CD8 T Cell Population
David Masopust, Vaiva Vezys, E. John Wherry, Daniel L. Barber and Rafi Ahmed

J Immunol February 15, 2006, 176 (4) 2079-2083; DOI: https://doi.org/10.4049/jimmunol.176.4.2079

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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CD11b⁺/Gr-1⁺ Myeloid Suppressor Cells Cause T Cell Dysfunction after Traumatic Stress
Valeriya P. Makarenkova, Vishal Bansal, Benjamin M. Matta, Lori Ann Perez and Juan B. Ochoa

J Immunol February 15, 2006, 176 (4) 2085-2094; DOI: https://doi.org/10.4049/jimmunol.176.4.2085
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Accelerated Macrophage Apoptosis Induces Autoantibody Formation and Organ Damage in Systemic Lupus Erythematosus
Michael F. Denny, Parthapratim Chandaroy, Paul D. Killen, Roberto Caricchio, Emily E. Lewis, Bruce C. Richardson, Kyung-Dall Lee, Jerrie Gavalchin and Mariana J. Kaplan

J Immunol February 15, 2006, 176 (4) 2095-2104; DOI: https://doi.org/10.4049/jimmunol.176.4.2095
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LFA-1-Dependent HuR Nuclear Export and Cytokine mRNA Stabilization in T Cell Activation
Jin Gene Wang, Mark Collinge, Vinod Ramgolam, Oran Ayalon, Xinhao Cynthia Fan, Ruggero Pardi and Jeffrey R. Bender

J Immunol February 15, 2006, 176 (4) 2105-2113; DOI: https://doi.org/10.4049/jimmunol.176.4.2105
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IL-3-Mediated TNF Production Is Necessary for Mast Cell Development
Harry V. Wright, Daniel Bailey, Mohit Kashyap, Christopher L. Kepley, Marina S. Drutskaya, Sergei A. Nedospasov and John J. Ryan

J Immunol February 15, 2006, 176 (4) 2114-2121; DOI: https://doi.org/10.4049/jimmunol.176.4.2114
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Role of MHC Class II on Memory B Cells in Post-Germinal Center B Cell Homeostasis and Memory Response
Michiko Shimoda, Tao Li, Jeanene P. S. Pihkala and Pandelakis A. Koni

J Immunol February 15, 2006, 176 (4) 2122-2133; DOI: https://doi.org/10.4049/jimmunol.176.4.2122
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Hyperthermia Enhances CTL Cross-Priming
Hongzhen Shi, Tinghua Cao, John E. Connolly, Laurence Monnet, Lynda Bennett, Sylvie Chapel, Claude Bagnis, Patrice Mannoni, Jean Davoust, A. Karolina Palucka and Jacques Banchereau

J Immunol February 15, 2006, 176 (4) 2134-2141; DOI: https://doi.org/10.4049/jimmunol.176.4.2134
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B Cell Tolerance Checkpoints That Restrict Pathways of Antigen-Driven Differentiation
Jacqueline William, Chad Euler, Nicole Primarolo and Mark J. Shlomchik

J Immunol February 15, 2006, 176 (4) 2142-2151; DOI: https://doi.org/10.4049/jimmunol.176.4.2142
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P2X₇ Receptors Regulate NKT Cells in Autoimmune Hepatitis
Hiroki Kawamura, Fred Aswad, Masahiro Minagawa, Sugantha Govindarajan and Gunther Dennert

J Immunol February 15, 2006, 176 (4) 2152-2160; DOI: https://doi.org/10.4049/jimmunol.176.4.2152
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A Major Lung CD103 (α_E)-β₇ Integrin-Positive Epithelial Dendritic Cell Population Expressing Langerin and Tight Junction Proteins
Sun-Sang J. Sung, Shu Man Fu, C. Edward Rose Jr., Felicia Gaskin, Shyr-Te Ju and Steven R. Beaty

J Immunol February 15, 2006, 176 (4) 2161-2172; DOI: https://doi.org/10.4049/jimmunol.176.4.2161
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Distinct Mechanisms Control Human Naive and Antigen-Experienced CD8⁺ T Lymphocyte Proliferation
Marco Migliaccio, Pedro Miguel Sousa Alves, Pedro Romero and Nathalie Rufer

J Immunol February 15, 2006, 176 (4) 2173-2182; DOI: https://doi.org/10.4049/jimmunol.176.4.2173
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NF-κB-Dependent Regulation of the Timing of Activation-Induced Cell Death of T Lymphocytes
Akanksha Mittal, Salvatore Papa, Guido Franzoso and Ranjan Sen

J Immunol February 15, 2006, 176 (4) 2183-2189; DOI: https://doi.org/10.4049/jimmunol.176.4.2183
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CD8 T Cells Specific for a Donor-Derived, Self-Restricted Transplant Antigen Are Nonpathogenic Bystanders after Vascularized Heart Transplantation in Mice
Anna Valujskikh, Qiwei Zhang and Peter S. Heeger

J Immunol February 15, 2006, 176 (4) 2190-2196; DOI: https://doi.org/10.4049/jimmunol.176.4.2190
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Expression and Regulation of the Orphan Receptor RDC1 and Its Putative Ligand in Human Dendritic and B Cells
Simona Infantino, Barbara Moepps and Marcus Thelen

J Immunol February 15, 2006, 176 (4) 2197-2207; DOI: https://doi.org/10.4049/jimmunol.176.4.2197
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Differential Role for Cyclic AMP Response Element Binding Protein-1 in Multiple Stages of B Cell Development, Differentiation, and Survival
Hui-Chen Chen, John C. Byrd and Natarajan Muthusamy

J Immunol February 15, 2006, 176 (4) 2208-2218; DOI: https://doi.org/10.4049/jimmunol.176.4.2208
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The JNK Are Important for Development and Survival of Macrophages
S. Roy Himes, David P. Sester, Timothy Ravasi, Stephen L. Cronau, Tedjo Sasmono and David A. Hume

J Immunol February 15, 2006, 176 (4) 2219-2228; DOI: https://doi.org/10.4049/jimmunol.176.4.2219
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Developmental Alterations in Thymocyte Sensitivity Are Actively Regulated by MHC Class II Expression in the Thymic Medulla
Steven C. Eck, Peimin Zhu, Marion Pepper, Steven J. Bensinger, Bruce D. Freedman and Terri M. Laufer

J Immunol February 15, 2006, 176 (4) 2229-2237; DOI: https://doi.org/10.4049/jimmunol.176.4.2229
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Mast Cells Enhance T Cell Activation: Importance of Mast Cell Costimulatory Molecules and Secreted TNF
Susumu Nakae, Hajime Suto, Motoyasu Iikura, Maki Kakurai, Jonathon D. Sedgwick, Mindy Tsai and Stephen J. Galli

J Immunol February 15, 2006, 176 (4) 2238-2248; DOI: https://doi.org/10.4049/jimmunol.176.4.2238
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Re-evaluating the Generation of a “Proteasome-Independent” MHC Class I-Restricted CD8 T Cell Epitope
E. John Wherry, Tatiana N. Golovina, Susan E. Morrison, Gomathinayagam Sinnathamby, Michael J. McElhaugh, David C. Shockey and Laurence C. Eisenlohr

J Immunol February 15, 2006, 176 (4) 2249-2261; DOI: https://doi.org/10.4049/jimmunol.176.4.2249
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Temporal and Dose-Dependent Relationships between In Vivo B Cell Receptor-Targeted Proliferation and Deletion-Induced by a Microbial B Cell Toxin
Carl S. Goodyear, Fujimi Sugiyama and Gregg J. Silverman

J Immunol February 15, 2006, 176 (4) 2262-2271; DOI: https://doi.org/10.4049/jimmunol.176.4.2262
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Human Mast Cells Undergo TRAIL-Induced Apoptosis
Beata Berent-Maoz, Adrian M. Piliponsky, Isabelle Daigle, Hans-Uwe Simon and Francesca Levi-Schaffer

J Immunol February 15, 2006, 176 (4) 2272-2278; DOI: https://doi.org/10.4049/jimmunol.176.4.2272
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Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States
Lynda Chiodetti, Seeyoung Choi, Daniel L. Barber and Ronald H. Schwartz

J Immunol February 15, 2006, 176 (4) 2279-2291; DOI: https://doi.org/10.4049/jimmunol.176.4.2279
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Antigen Exposure during Enhanced CTLA-4 Expression Promotes Allograft Tolerance In Vivo
Paolo R. O. Salvalaggio, Geoffrey Camirand, Charlotte E. Ariyan, Songyan Deng, Linda Rogozinski, Giacomo P. Basadonna and David M. Rothstein

J Immunol February 15, 2006, 176 (4) 2292-2298; DOI: https://doi.org/10.4049/jimmunol.176.4.2292
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Thymocyte Negative Selection Is Mediated by Protein Kinase C- and Ca²⁺-Dependent Transcriptional Induction of Bim
Kirsten Canté-Barrett, Elena M. Gallo, Monte M. Winslow and Gerald R. Crabtree

J Immunol February 15, 2006, 176 (4) 2299-2306; DOI: https://doi.org/10.4049/jimmunol.176.4.2299
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CD4-Dependent Potentiation of a High Molecular Weight-Melanoma-Associated Antigen-Specific CTL Response Elicited in HLA-A2/K^b Transgenic Mice
Liaomin Peng, Eric Ko, Wei Luo, Xinhui Wang, Protul A. Shrikant and Soldano Ferrone

J Immunol February 15, 2006, 176 (4) 2307-2315; DOI: https://doi.org/10.4049/jimmunol.176.4.2307
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Effector and Memory CD8⁺ T Cells Can Be Generated in Response to Alloantigen Independently of CD4⁺ T Cell Help
Nick D. Jones, Manuela Carvalho-Gaspar, Shiqiao Luo, Matthew O. Brook, Laurent Martin and Kathryn J. Wood

J Immunol February 15, 2006, 176 (4) 2316-2323; DOI: https://doi.org/10.4049/jimmunol.176.4.2316
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Frequency of Natural Regulatory CD4⁺CD25⁺ T Lymphocytes Determines the Outcome of Tolerance across Fully Mismatched MHC Barrier through Linked Recognition of Self and Allogeneic Stimuli
Rita Fucs, Joszilene T. Jesus, Paulo H. N. Souza Junior, Larissa Franco, Mauricio Verícimo, Maria Bellio and Alberto Nobrega

J Immunol February 15, 2006, 176 (4) 2324-2329; DOI: https://doi.org/10.4049/jimmunol.176.4.2324
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Ex Vivo Characterization of Allo-MHC-Restricted T Cells Specific for a Single MHC-Peptide Complex
Mikaël J. Pittet, Asma Gati, Frederic-Anne Le Gal, Gilles Bioley, Philippe Guillaume, Magda de Smedt, Jean Plum, Daniel E. Speiser, Jean-Charles Cerottini, Pierre-Yves Dietrich, Pedro Romero and Alfred Zippelius

J Immunol February 15, 2006, 176 (4) 2330-2336; DOI: https://doi.org/10.4049/jimmunol.176.4.2330
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Chemokine Receptor CXCR3 Desensitization by IL-16/CD4 Signaling Is Dependent on CCR5 and Intact Membrane Cholesterol
Shilpa Rahangdale, Roger Morgan, Claudia Heijens, Thomas C. Ryan, Hisato Yamasaki, Elizabeth Bentley, Elizabeth Sullivan, David M. Center and William W. Cruikshank

J Immunol February 15, 2006, 176 (4) 2337-2345; DOI: https://doi.org/10.4049/jimmunol.176.4.2337
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CCL5 Modulates Pneumococcal Immunity and Carriage
Ravichandran Palaniappan, Shailesh Singh, Udai P. Singh, Rajesh Singh, Edwin W. Ades, David E. Briles, Susan K. Hollingshead, Walter Royal III, Jacquelyn S. Sampson, Jonathan K. Stiles, Dennis D. Taub and James W. Lillard Jr.

J Immunol February 15, 2006, 176 (4) 2346-2356; DOI: https://doi.org/10.4049/jimmunol.176.4.2346
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Langerhans-Type Dendritic Cells Genetically Modified to Express Full-Length Antigen Optimally Stimulate CTLs in a CD4-Dependent Manner
Jianda Yuan, Jean-Baptiste Latouche, Joanna Hodges, Alan N. Houghton, Glenn Heller, Michel Sadelain, Isabelle Riviere and James W. Young

J Immunol February 15, 2006, 176 (4) 2357-2365; DOI: https://doi.org/10.4049/jimmunol.176.4.2357
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A Polymeric Bacterial Protein Activates Dendritic Cells via TLR4
Paula M. Berguer, Juliana Mundiñano, Isabel Piazzon and Fernando A. Goldbaum

J Immunol February 15, 2006, 176 (4) 2366-2372; DOI: https://doi.org/10.4049/jimmunol.176.4.2366

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Meningococcal Porin PorB Binds to TLR2 and Requires TLR1 for Signaling
Paola Massari, Alberto Visintin, Jay Gunawardana, Kristen A. Halmen, Carol A. King, Douglas T. Golenbock and Lee M. Wetzler

J Immunol February 15, 2006, 176 (4) 2373-2380; DOI: https://doi.org/10.4049/jimmunol.176.4.2373
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Position-Dependent Repression and Promotion of DQB1 Intron 3 Splicing by GGGG Motifs
Jana Královic̆ová and Igor Vor̆echovský

J Immunol February 15, 2006, 176 (4) 2381-2388; DOI: https://doi.org/10.4049/jimmunol.176.4.2381
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B Cell-Specific Deficiency for Smad2 In Vivo Leads to Defects in TGF-β-Directed IgA Switching and Changes in B Cell Fate
Jörg Klein, Wenjun Ju, Jörg Heyer, Britta Wittek, Torsten Haneke, Petra Knaus, Raju Kucherlapati, Erwin P. Böttinger, Lars Nitschke and Burkhard Kneitz

J Immunol February 15, 2006, 176 (4) 2389-2396; DOI: https://doi.org/10.4049/jimmunol.176.4.2389
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CD161 (Human NKR-P1A) Signaling in NK Cells Involves the Activation of Acid Sphingomyelinase
David Pozo, Mar Valés-Gómez, Nasim Mavaddat, Sharon C. Williamson, Susan E. Chisholm and Hugh Reyburn

J Immunol February 15, 2006, 176 (4) 2397-2406; DOI: https://doi.org/10.4049/jimmunol.176.4.2397
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Involvement of Protein Kinase Cε in the Negative Regulation of Akt Activation Stimulated by Granulocyte Colony-Stimulating Factor
Hong Liu, Yaling Qiu, Lei Xiao and Fan Dong

J Immunol February 15, 2006, 176 (4) 2407-2413; DOI: https://doi.org/10.4049/jimmunol.176.4.2407
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Endotoxin-Induced Down-Regulation of Elk-3 Facilitates Heme Oxygenase-1 Induction in Macrophages
Su Wol Chung, Yen-Hsu Chen, Shaw-Fang Yet, Matthew D. Layne and Mark A. Perrella

J Immunol February 15, 2006, 176 (4) 2414-2420; DOI: https://doi.org/10.4049/jimmunol.176.4.2414
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Scaffolding Adapter Grb2-Associated Binder 2 Requires Syk to Transmit Signals from FcεRI
Min Yu, Cliff A. Lowell, Benjamin G. Neel and Haihua Gu

J Immunol February 15, 2006, 176 (4) 2421-2429; DOI: https://doi.org/10.4049/jimmunol.176.4.2421
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Functional Hierarchy of the N-Terminal Tyrosines of SLP-76
Martha S. Jordan, Jeffrey Sadler, Jessica E. Austin, Lisa D. Finkelstein, Andrew L. Singer, Pamela L. Schwartzberg and Gary A. Koretzky

J Immunol February 15, 2006, 176 (4) 2430-2438; DOI: https://doi.org/10.4049/jimmunol.176.4.2430
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Regulation of IgH Gene Assembly: Role of the Intronic Enhancer and 5′D_Q52 Region in Targeting D_HJ_H Recombination
Roshi Afshar, Steven Pierce, Daniel J. Bolland, Anne Corcoran and Eugene M. Oltz

J Immunol February 15, 2006, 176 (4) 2439-2447; DOI: https://doi.org/10.4049/jimmunol.176.4.2439

IMMUNOGENETICS

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The Molecular Basis for Galα(1,3)Gal Expression in Animals with a Deletion of the α1,3Galactosyltransferase Gene
Julie Milland, Dale Christiansen, Brooke D. Lazarus, Simon G. Taylor, Pei Xiang Xing and Mauro S. Sandrin

J Immunol February 15, 2006, 176 (4) 2448-2454; DOI: https://doi.org/10.4049/jimmunol.176.4.2448

HOST DEFENSE

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Modulation of the TLR-Mediated Inflammatory Response by the Endogenous Human Host Defense Peptide LL-37
Neeloffer Mookherjee, Kelly L. Brown, Dawn M. E. Bowdish, Silvana Doria, Reza Falsafi, Karsten Hokamp, Fiona M. Roche, Ruixia Mu, Gregory H. Doho, Jelena Pistolic, Jon-Paul Powers, Jenny Bryan, Fiona S. L. Brinkman and Robert E. W. Hancock

J Immunol February 15, 2006, 176 (4) 2455-2464; DOI: https://doi.org/10.4049/jimmunol.176.4.2455
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Transepithelial Pathogen Uptake into the Small Intestinal Lamina Propria
Alexandra Vallon-Eberhard, Limor Landsman, Nir Yogev, Bernard Verrier and Steffen Jung

J Immunol February 15, 2006, 176 (4) 2465-2469; DOI: https://doi.org/10.4049/jimmunol.176.4.2465
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Cytolytic CD8⁺ T Cells Directed against a Cryptic Epitope Derived from a Retroviral Alternative Reading Frame Confer Disease Protection
On Ho and William R. Green

J Immunol February 15, 2006, 176 (4) 2470-2475; DOI: https://doi.org/10.4049/jimmunol.176.4.2470
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Activation of Invariant NKT Cells by the Helminth Parasite Schistosoma mansoni
Thierry Mallevaey, Jean Pierre Zanetta, Christelle Faveeuw, Josette Fontaine, Emmanuel Maes, Frances Platt, Monique Capron, Maria Leite- de-Moraes and François Trottein

J Immunol February 15, 2006, 176 (4) 2476-2485; DOI: https://doi.org/10.4049/jimmunol.176.4.2476
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OX40 Ligation of CD4⁺ T Cells Enhances Virus-Specific CD8⁺ T Cell Memory Responses Independently of IL-2 and CD4⁺ T Regulatory Cell Inhibition
Qigui Yu, Feng Yun Yue, Xiao X. Gu, Herbert Schwartz, Colin M. Kovacs and Mario A. Ostrowski

J Immunol February 15, 2006, 176 (4) 2486-2495; DOI: https://doi.org/10.4049/jimmunol.176.4.2486
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Impaired Protection against Mycobacterium bovis Bacillus Calmette-Guérin Infection in IL-15-Deficient Mice
Kimika Saito, Toshiki Yajima, Shino Kumabe, Takehiko Doi, Hisakata Yamada, Subash Sad, Hao Shen and Yasunobu Yoshikai

J Immunol February 15, 2006, 176 (4) 2496-2504; DOI: https://doi.org/10.4049/jimmunol.176.4.2496
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Induction of Enhanced Immunity to Intestinal Nematodes Using IL-9-Producing Dendritic Cells
Melanie D. Leech and Richard K. Grencis

J Immunol February 15, 2006, 176 (4) 2505-2511; DOI: https://doi.org/10.4049/jimmunol.176.4.2505

INFLAMMATION

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Gliadin Stimulation of Murine Macrophage Inflammatory Gene Expression and Intestinal Permeability Are MyD88-Dependent: Role of the Innate Immune Response in Celiac Disease
Karen E. Thomas, Anna Sapone, Alessio Fasano and Stefanie N. Vogel

J Immunol February 15, 2006, 176 (4) 2512-2521; DOI: https://doi.org/10.4049/jimmunol.176.4.2512
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Proinflammatory Cytokine Production in Liver Regeneration Is Myd88-Dependent, but Independent of Cd14, Tlr2, and Tlr4
Jean S. Campbell, Kimberly J. Riehle, John T. Brooling, Renay L. Bauer, Claudia Mitchell and Nelson Fausto

J Immunol February 15, 2006, 176 (4) 2522-2528; DOI: https://doi.org/10.4049/jimmunol.176.4.2522
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Priming of Glomerular Mesangial Cells by Activated Macrophages Causes Blunted Responses to Proinflammatory Stimuli
Kunihiro Hayakawa, Yiman Meng, Nobuhiko Hiramatsu, Ayumi Kasai, Kozue Yamauchi, Jian Yao and Masanori Kitamura

J Immunol February 15, 2006, 176 (4) 2529-2537; DOI: https://doi.org/10.4049/jimmunol.176.4.2529
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Neutrophils Regulate Airway Responses in a Model of Fungal Allergic Airways Disease
Stacy J. Park, Maria T. Wiekowski, Sergio A. Lira and Borna Mehrad

J Immunol February 15, 2006, 176 (4) 2538-2545; DOI: https://doi.org/10.4049/jimmunol.176.4.2538
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Impaired GATA3-Dependent Chromatin Remodeling and Th2 Cell Differentiation Leading to Attenuated Allergic Airway Inflammation in Aging Mice
Akihiro Hasegawa, Takako Miki, Hiroyuki Hosokawa, Mohammad B. Hossain, Chiori Shimizu, Kahoko Hashimoto, Motoko Y. Kimura, Masakatsu Yamashita and Toshinori Nakayama

J Immunol February 15, 2006, 176 (4) 2546-2554; DOI: https://doi.org/10.4049/jimmunol.176.4.2546
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Involvement of Group VIA Calcium-Independent Phospholipase A₂ in Macrophage Engulfment of Hydrogen Peroxide-Treated U937 Cells
Rebeca Pérez, María A. Balboa and Jesús Balsinde

J Immunol February 15, 2006, 176 (4) 2555-2561; DOI: https://doi.org/10.4049/jimmunol.176.4.2555
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Deletion of CCR1 Attenuates Pathophysiologic Responses during Respiratory Syncytial Virus Infection
Allison L. Miller, Craig Gerard, Matthew Schaller, Achim D. Gruber, Allison A. Humbles and Nicholas W. Lukacs

J Immunol February 15, 2006, 176 (4) 2562-2567; DOI: https://doi.org/10.4049/jimmunol.176.4.2562
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Inhalation Tolerance Is Induced Selectively in Thoracic Lymph Nodes but Executed Pervasively at Distant Mucosal and Nonmucosal Tissues
David Alvarez, Filip K. Swirski, Teng-Chih Yang, Ramzi Fattouh, Ken Croitoru, Jonathan L. Bramson, Martin R. Stämpfli and Manel Jordana

J Immunol February 15, 2006, 176 (4) 2568-2580; DOI: https://doi.org/10.4049/jimmunol.176.4.2568
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Epithelial CXCR3-B Regulates Chemokines Bioavailability in Normal, but Not in Sjögren’s Syndrome, Salivary Glands
Paolo Sfriso, Francesca Oliviero, Fiorella Calabrese, Marta Miorin, Monica Facco, Antonella Contri, Anna Cabrelle, Ilenia Baesso, Franco Cozzi, Marilisa Andretta, Marco Antonio Cassatella, Ugo Fiocco, Silvano Todesco, Yrjö T. Konttinen, Leonardo Punzi and Carlo Agostini

J Immunol February 15, 2006, 176 (4) 2581-2589; DOI: https://doi.org/10.4049/jimmunol.176.4.2581

CLINICAL IMMUNOLOGY

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Ceramide-Dependent Regulation of Human Epidermal Keratinocyte CD1d Expression during Terminal Differentiation
Rita Fishelevich, Alla Malanina, Irina Luzina, Sergei Atamas, Miriam J. Smyth, Steven A. Porcelli and Anthony A. Gaspari

J Immunol February 15, 2006, 176 (4) 2590-2599; DOI: https://doi.org/10.4049/jimmunol.176.4.2590
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The Shaving Reaction: Rituximab/CD20 Complexes Are Removed from Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Cells by THP-1 Monocytes
Paul V. Beum, Adam D. Kennedy, Michael E. Williams, Margaret A. Lindorfer and Ronald P. Taylor

J Immunol February 15, 2006, 176 (4) 2600-2609; DOI: https://doi.org/10.4049/jimmunol.176.4.2600
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Human NK Cells Positively Regulate γδ T Cells in Response to Mycobacterium tuberculosis
Ruijun Zhang, Xiaodong Zheng, Baiqing Li, Haiming Wei and Zhigang Tian

J Immunol February 15, 2006, 176 (4) 2610-2616; DOI: https://doi.org/10.4049/jimmunol.176.4.2610
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TNF-α Blockade Down-Regulates the CD40/CD40L Pathway in the Mucosal Microcirculation: A Novel Anti-Inflammatory Mechanism of Infliximab in Crohn’s Disease
Silvio Danese, Miquel Sans, Franco Scaldaferri, Alessandro Sgambato, Sergio Rutella, Achille Cittadini, Josep M. Piqué, Julian Panes, Jeffry A. Katz, Antonio Gasbarrini and Claudio Fiocchi

J Immunol February 15, 2006, 176 (4) 2617-2624; DOI: https://doi.org/10.4049/jimmunol.176.4.2617
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Persistent Cytomegalovirus-Specific Memory Responses in the Lung Allograft and Blood following Primary Infection in Lung Transplant Recipients
Oksana A. Shlobin, Erin E. West, Noah Lechtzin, Susan M. Miller, Marvin Borja, Jonathan B. Orens, Lesia K. Dropulic and John F. McDyer

J Immunol February 15, 2006, 176 (4) 2625-2634; DOI: https://doi.org/10.4049/jimmunol.176.4.2625
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Tolerance Induction by Transcutaneous Immunization through Ultraviolet-Irradiated Skin Is Transferable through CD4⁺CD25⁺ T Regulatory Cells and Is Dependent on Host-Derived IL-10
Mehran Ghoreishi and Jan P. Dutz

J Immunol February 15, 2006, 176 (4) 2635-2644; DOI: https://doi.org/10.4049/jimmunol.176.4.2635
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Longitudinal Studies of Clonally Expanded CD8 T Cells Reveal a Repertoire Shrinkage Predicting Mortality and an Increased Number of Dysfunctional Cytomegalovirus-Specific T Cells in the Very Elderly
Sine Reker Hadrup, Jan Strindhall, Tania Køllgaard, Tina Seremet, Boo Johansson, Graham Pawelec, Per thor Straten and Anders Wikby

J Immunol February 15, 2006, 176 (4) 2645-2653; DOI: https://doi.org/10.4049/jimmunol.176.4.2645
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B Cells Are Crucial for Determinant Spreading of T Cell Autoimmunity among β Cell Antigens in Diabetes-Prone Nonobese Diabetic Mice
Jide Tian, Dan Zekzer, Yuxin Lu, Hoa Dang and Daniel L. Kaufman

J Immunol February 15, 2006, 176 (4) 2654-2661; DOI: https://doi.org/10.4049/jimmunol.176.4.2654
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HIV-Specific Cytotoxic Cell Frequencies Measured Directly Ex Vivo by the Lysispot Assay Can Be Higher or Lower Than the Frequencies of IFN-γ-Secreting Cells: Anti-HIV Cytotoxicity Is Not Generally Impaired Relative to Other Chronic Virus Responses
Jennifer E. Snyder-Cappione, Anagha A. Divekar, Genny M. Maupin, Xia Jin, Lisa M. Demeter and Tim R. Mosmann

J Immunol February 15, 2006, 176 (4) 2662-2668; DOI: https://doi.org/10.4049/jimmunol.176.4.2662

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Constitutively active protein kinase B enhances Lck and Erk activities and influences thymocyte selection and activation.
S.-Y. Na, A. Patra, Y. Scheuring, A. Marx, M. Tolaini, D. Kioussis, B. Hemmings, T. Hünig and U. Bommhardt

J Immunol February 15, 2006, 176 (4) 2669; DOI: https://doi.org/10.4049/jimmunol.176.4.2669
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Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity
M. M. Wurfel, W. Y. Park, F. Radella, J. Ruzinski, A. Sandstrom, J. Strout, R. E. Bumgarner and T. R. Martin

J Immunol February 15, 2006, 176 (4) 2669; DOI: https://doi.org/10.4049/jimmunol.176.4.2669-a
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HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent
Y.-J. Jin, C. Y. Cai, X. Zhang, H.-T. Zhang, J. A. Hirst and S. J. Burakoff

J Immunol February 15, 2006, 176 (4) 2669; DOI: https://doi.org/10.4049/jimmunol.176.4.2669-b
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The Nef protein of HIV-1 induces loss of cell surface costimulatory molecules CD80 and CD86 in APCs
A. Chaudhry, S. R. Das, A. Hussain, S. Mayor, A. George, V. Bal, S. Jameel and S. Rath

J Immunol February 15, 2006, 176 (4) 2670; DOI: https://doi.org/10.4049/jimmunol.176.4.2670
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Defined blocks in terminal plasma cell differentiation of common variable immunodeficiency patients
N. Taubenheim, M. von Hornung, A. Durandy, K. Warnatz, L. Corcoran, H.-H. Peter and H. Eibel

J Immunol February 15, 2006, 176 (4) 2670; DOI: https://doi.org/10.4049/jimmunol.176.4.2670-a
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Granzyme B, a new player in activation-induced cell death, is down-regulated by vasoactive intestinal peptide in Th2 but not Th1 effectors
V. Sharma, M. Delgado and D. Ganea

J Immunol February 15, 2006, 176 (4) 2670; DOI: https://doi.org/10.4049/jimmunol.176.4.2670-b
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B7⁺ iris pigment epithelium induce CD8⁺ T regulatory cells; both suppress CTLA-4⁺ T cells
S. Sugita, T. F. Ng, P. J. Lucas, R. E. Gress and J. W. Streilein

J Immunol February 15, 2006, 176 (4) 2670; DOI: https://doi.org/10.4049/jimmunol.176.4.2670-c
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Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs
H. Matsue, J. Yao, K. Matsue, A. Nagasaka, H. Sugiyama, R. Aoki, M. Kitamura and S. Shimada

J Immunol February 15, 2006, 176 (4) 2670; DOI: https://doi.org/10.4049/jimmunol.176.4.2670-d
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Chemotactic responses of IL-4-, IL-10-, and IFN-γ-producing CD4⁺ T cells depend on tissue origin and microbial stimulus
G. F. Debes, M. E. Dahl, A. J. Mahiny, K. Bonhagen, D. J. Campbell, K. Siegmund, K. J. Erb, D. B. Lewis, T. Kamradt and A. Hamann

J Immunol February 15, 2006, 176 (4) 2671; DOI: https://doi.org/10.4049/jimmunol.176.4.2671
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Lipoteichoic acid-induced nitric oxide production depends on the activation of platelet-activating factor receptor and Jak2
S. H. Han, J. H. Kim, H. S. Seo, M. H. Martin, G.-H. Chung, S. M. Michalek and M. H. Nahm

J Immunol February 15, 2006, 176 (4) 2671; DOI: https://doi.org/10.4049/jimmunol.176.4.2671-a
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Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF-α production
Y. Fu, C. Xie, J. Chen, J. Zhu, H. Zhou, J. Thomas, X. J. Zhou and C. Mohan

J Immunol February 15, 2006, 176 (4) 2671; DOI: https://doi.org/10.4049/jimmunol.176.4.2671-b

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BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

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CLINICAL IMMUNOLOGY

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