The Journal of Immunology: 176 (3)

February 1, 2006; Volume 176,Issue 3

IN THIS ISSUE

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IN THIS ISSUE

J Immunol February 1, 2006, 176 (3) 1293-1294; DOI: https://doi.org/10.4049/jimmunol.176.3.1293

PILLARS OF IMMUNOLOGY

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In the Beginning Was Sm
George C. Tsokos

J Immunol February 1, 2006, 176 (3) 1295-1296; DOI: https://doi.org/10.4049/jimmunol.176.3.1295
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Pillars Article: Characteristics of a Soluble Nuclear Antigen Precipitating with Sera of Patients with Systemic Lupus Erythematosus. J. Immunol. 1966. 96: 464–471.
E. M. Tan and H. G. Kunkel

J Immunol February 1, 2006, 176 (3) 1297-1304;

BRIEF REVIEWS

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The Central Role of the Alternative Complement Pathway in Human Disease
Joshua M. Thurman and V. Michael Holers

J Immunol February 1, 2006, 176 (3) 1305-1310; DOI: https://doi.org/10.4049/jimmunol.176.3.1305

CUTTING EDGE

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Cutting Edge: Identification of E-Cadherin as a Ligand for the Murine Killer Cell Lectin-Like Receptor G1
Carsten Gründemann, Monika Bauer, Oliver Schweier, Nanette von Oppen, Ute Lässing, Philippe Saudan, Karl-Friedrich Becker, Klaus Karp, Thomas Hanke, Martin F. Bachmann and Hanspeter Pircher

J Immunol February 1, 2006, 176 (3) 1311-1315; DOI: https://doi.org/10.4049/jimmunol.176.3.1311
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Cutting Edge: Deficiency in the E3 Ubiquitin Ligase Cbl-b Results in a Multifunctional Defect in T Cell TGF-β Sensitivity In Vitro and In Vivo
Elizabeth A. Wohlfert, Leonid Gorelik, Robert Mittler, Richard A. Flavell and Robert B. Clark

J Immunol February 1, 2006, 176 (3) 1316-1320; DOI: https://doi.org/10.4049/jimmunol.176.3.1316
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Cutting Edge: A Novel Nonoxidative Phagosomal Mechanism Exerted by Cathepsin-D Controls Listeria monocytogenes Intracellular Growth
Elida del Cerro-Vadillo, Fidel Madrazo-Toca, Eugenio Carrasco-Marín, Lorena Fernandez-Prieto, Christian Beck, Francisco Leyva-Cobián, Paul Saftig and Carmen Alvarez-Dominguez

J Immunol February 1, 2006, 176 (3) 1321-1325; DOI: https://doi.org/10.4049/jimmunol.176.3.1321
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Cutting Edge: Prostaglandin D₂ Enhances Leukotriene C₄ Synthesis by Eosinophils during Allergic Inflammation: Synergistic In Vivo Role of Endogenous Eotaxin
Fabio P. Mesquita-Santos, Adriana Vieira-de-Abreu, Andrea S. Calheiros, Isabela H. Figueiredo, Hugo C. Castro-Faria-Neto, Peter F. Weller, Patrícia T. Bozza, Bruno L. Diaz and Christianne Bandeira-Melo

J Immunol February 1, 2006, 176 (3) 1326-1330; DOI: https://doi.org/10.4049/jimmunol.176.3.1326

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Soluble HLA-G Inhibits Cell Cycle Progression in Human Alloreactive T Lymphocytes
Rajia Bahri, Francois Hirsch, Adeline Josse, Nathalie Rouas-Freiss, Nicolas Bidere, Aime Vasquez, Edgardo D. Carosella, Bernard Charpentier and Antoine Durrbach

J Immunol February 1, 2006, 176 (3) 1331-1339; DOI: https://doi.org/10.4049/jimmunol.176.3.1331
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The Endoplasmic Reticulum Is a Key Component of the Plasma Cell Death Pathway
Nadège Pelletier, Montserrat Casamayor-Pallejà, Karelle De Luca, Paul Mondière, Frédéric Saltel, Pierre Jurdic, Chantal Bella, Laurent Genestier and Thierry Defrance

J Immunol February 1, 2006, 176 (3) 1340-1347; DOI: https://doi.org/10.4049/jimmunol.176.3.1340
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Direct Costimulatory Effect of TLR3 Ligand Poly(I:C) on Human γδ T Lymphocytes
Daniela Wesch, Susann Beetz, Hans-Heinrich Oberg, Matthias Marget, Kirsten Krengel and Dieter Kabelitz

J Immunol February 1, 2006, 176 (3) 1348-1354; DOI: https://doi.org/10.4049/jimmunol.176.3.1348
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Flightless I Homolog Negatively Modulates the TLR Pathway
Tianyi Wang, Tsung-Hsien Chuang, Tapani Ronni, Sheng Gu, Yu-Chun Du, Hong Cai, Hui-Qiao Sun, Helen L. Yin and Xian Chen

J Immunol February 1, 2006, 176 (3) 1355-1362; DOI: https://doi.org/10.4049/jimmunol.176.3.1355
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Immunologic Control of Tumors by In Vivo Fcγ Receptor-Targeted Antigen Loading in Conjunction with Double-Stranded RNA-Mediated Immune Modulation
Adrian Bot, Dan Smith, Bill Phillips, Simona Bot, Constantin Bona and Habib Zaghouani

J Immunol February 1, 2006, 176 (3) 1363-1374; DOI: https://doi.org/10.4049/jimmunol.176.3.1363
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Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function
Cunren Liu, Shaohua Yu, Kurt Zinn, Jianhua Wang, Liming Zhang, Yujiang Jia, John C. Kappes, Stephen Barnes, Robert P. Kimberly, William E. Grizzle and Huang-Ge Zhang

J Immunol February 1, 2006, 176 (3) 1375-1385; DOI: https://doi.org/10.4049/jimmunol.176.3.1375
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Potentiation of Antigen-Stimulated Vγ9Vδ2 T Cell Cytokine Production by Immature Dendritic Cells (DC) and Reciprocal Effect on DC Maturation
Marie-Claire Devilder, Sophie Maillet, Isabelle Bouyge-Moreau, Emmanuel Donnadieu, Marc Bonneville and Emmanuel Scotet

J Immunol February 1, 2006, 176 (3) 1386-1393; DOI: https://doi.org/10.4049/jimmunol.176.3.1386
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Critical, but Conditional, Role of OX40 in Memory T Cell-Mediated Rejection
Minh Diem Vu, Michael R. Clarkson, Hideo Yagita, Laurence A. Turka, Mohamed H. Sayegh and Xian Chang Li

J Immunol February 1, 2006, 176 (3) 1394-1401; DOI: https://doi.org/10.4049/jimmunol.176.3.1394
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CD40 Expression by Microglial Cells Is Required for Their Completion of a Two-Step Activation Process during Central Nervous System Autoimmune Inflammation
Eugene D. Ponomarev, Leah P. Shriver and Bonnie N. Dittel

J Immunol February 1, 2006, 176 (3) 1402-1410; DOI: https://doi.org/10.4049/jimmunol.176.3.1402
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Soluble Form of T Cell Ig Mucin 3 Is an Inhibitory Molecule in T Cell-Mediated Immune Response
Hui Geng, Gui-Mei Zhang, Dong Li, Hui Zhang, Ye Yuan, Han-Gang Zhu, Han Xiao, Ling-Fei Han and Zuo-Hua Feng

J Immunol February 1, 2006, 176 (3) 1411-1420; DOI: https://doi.org/10.4049/jimmunol.176.3.1411
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A Cell-Type Specific CD1d Expression Program Modulates Invariant NKT Cell Development and Function
Michael I. Zimmer, Angela Colmone, Kyrie Felio, Honglin Xu, Averil Ma and Chyung-Ru Wang

J Immunol February 1, 2006, 176 (3) 1421-1430; DOI: https://doi.org/10.4049/jimmunol.176.3.1421
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Protein Expression of TNF-α in Psoriatic Skin Is Regulated at a Posttranscriptional Level by MAPK-Activated Protein Kinase 2
Claus Johansen, Anne Toftegaard Funding, Kristian Otkjaer, Knud Kragballe, Uffe Birk Jensen, Mogens Madsen, Lise Binderup, Tine Skak-Nielsen, Marianne Scheel Fjording and Lars Iversen

J Immunol February 1, 2006, 176 (3) 1431-1438; DOI: https://doi.org/10.4049/jimmunol.176.3.1431
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Human Naive CD8 T Cells Down-Regulate Expression of the WNT Pathway Transcription Factors Lymphoid Enhancer Binding Factor 1 and Transcription Factor 7 (T Cell Factor-1) following Antigen Encounter In Vitro and In Vivo
Tim Willinger, Tom Freeman, Mark Herbert, Hitoshi Hasegawa, Andrew J. McMichael and Margaret F. C. Callan

J Immunol February 1, 2006, 176 (3) 1439-1446; DOI: https://doi.org/10.4049/jimmunol.176.3.1439
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Tumor-Specific CD4⁺ T Cells Are Activated by “Cross-Dressed” Dendritic Cells Presenting Peptide-MHC Class II Complexes Acquired from Cell-Based Cancer Vaccines
Brian P. Dolan, Kenneth D. Gibbs Jr. and Suzanne Ostrand-Rosenberg

J Immunol February 1, 2006, 176 (3) 1447-1455; DOI: https://doi.org/10.4049/jimmunol.176.3.1447
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CXCR3/CXCR3 Ligand Biological Axis Impairs RENCA Tumor Growth by a Mechanism of Immunoangiostasis
Judong Pan, Marie D. Burdick, John A. Belperio, Ying Ying Xue, Craig Gerard, Sherven Sharma, Steven M. Dubinett and Robert M. Strieter

J Immunol February 1, 2006, 176 (3) 1456-1464; DOI: https://doi.org/10.4049/jimmunol.176.3.1456
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Protein Vaccines Induce Uncommitted IL-2-Secreting Human and Mouse CD4 T Cells, Whereas Infections Induce More IFN-γ-Secreting Cells
Anagha A. Divekar, Dietmar M. W. Zaiss, F. Eun-Hyung Lee, Dacheng Liu, David J. Topham, Alice J. A. M. Sijts and Tim R. Mosmann

J Immunol February 1, 2006, 176 (3) 1465-1473; DOI: https://doi.org/10.4049/jimmunol.176.3.1465
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Enhanced FTY720-Mediated Lymphocyte Homing Requires Gαi Signaling and Depends on β₂ and β₇ Integrin
Oliver Pabst, Heike Herbrand, Stefanie Willenzon, Tim Worbs, Angela Schippers, Werner Müller, Günter Bernhardt and Reinhold Förster

J Immunol February 1, 2006, 176 (3) 1474-1480; DOI: https://doi.org/10.4049/jimmunol.176.3.1474
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Splenic Dendritic Cells Induced by Oral Antigen Administration Are Important for the Transfer of Oral Tolerance in an Experimental Model of Asthma
Katsuya Nagatani, Makoto Dohi, Yasuo To, Ryoichi Tanaka, Katsuhide Okunishi, Kazuyuki Nakagome, Kayo Sagawa, Yudo Tanno, Yoshinori Komagata and Kazuhiko Yamamoto

J Immunol February 1, 2006, 176 (3) 1481-1489; DOI: https://doi.org/10.4049/jimmunol.176.3.1481
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IL-21 Down-Regulates NKG2D/DAP10 Expression on Human NK and CD8⁺ T Cells
Steven J. Burgess, Alina I. Marusina, Ishani Pathmanathan, Francisco Borrego and John E. Coligan

J Immunol February 1, 2006, 176 (3) 1490-1497; DOI: https://doi.org/10.4049/jimmunol.176.3.1490
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CD8 T Cells, Like CD4 T Cells, Are Triggered by Multivalent Engagement of TCRs by MHC-Peptide Ligands but Not by Monovalent Engagement
Jennifer D. Stone and Lawrence J. Stern

J Immunol February 1, 2006, 176 (3) 1498-1505; DOI: https://doi.org/10.4049/jimmunol.176.3.1498
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Expansion of Functionally Immature Transitional B Cells Is Associated with Human-Immunodeficient States Characterized by Impaired Humoral Immunity
Amanda K. Cuss, Danielle T. Avery, Jennifer L. Cannons, Li Jun Yu, Kim E. Nichols, Peter J. Shaw and Stuart G. Tangye

J Immunol February 1, 2006, 176 (3) 1506-1516; DOI: https://doi.org/10.4049/jimmunol.176.3.1506
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CD27 Dissects Mature NK Cells into Two Subsets with Distinct Responsiveness and Migratory Capacity
Yoshihiro Hayakawa and Mark J. Smyth

J Immunol February 1, 2006, 176 (3) 1517-1524; DOI: https://doi.org/10.4049/jimmunol.176.3.1517
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Therapeutic Vaccination of Active Arthritis with a Glycosylated Collagen Type II Peptide in Complex with MHC Class II Molecules
Balik Dzhambazov, Kutty Selva Nandakumar, Jan Kihlberg, Lars Fugger, Rikard Holmdahl and Mikael Vestberg

J Immunol February 1, 2006, 176 (3) 1525-1533; DOI: https://doi.org/10.4049/jimmunol.176.3.1525
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Pregnancy-Associated Exosomes and Their Modulation of T Cell Signaling
Douglas D. Taylor, Sibel Akyol and Cicek Gercel-Taylor

J Immunol February 1, 2006, 176 (3) 1534-1542; DOI: https://doi.org/10.4049/jimmunol.176.3.1534
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Human αβ and γδ Thymocyte Development: TCR Gene Rearrangements, Intracellular TCRβ Expression, and γδ Developmental Potential—Differences between Men and Mice
Michelle L. Joachims, Jennifer L. Chain, Scott W. Hooker, Christopher J. Knott-Craig and Linda F. Thompson

J Immunol February 1, 2006, 176 (3) 1543-1552; DOI: https://doi.org/10.4049/jimmunol.176.3.1543
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Responsiveness of Naive CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation
Natallia Mikhalkevich, Brian Becknell, Michael A. Caligiuri, Michael D. Bates, Richard Harvey and Wei-ping Zheng

J Immunol February 1, 2006, 176 (3) 1553-1560; DOI: https://doi.org/10.4049/jimmunol.176.3.1553
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TLR Agonists Abrogate Costimulation Blockade-Induced Prolongation of Skin Allografts
Thomas B. Thornley, Michael A. Brehm, Thomas G. Markees, Leonard D. Shultz, John P. Mordes, Raymond M. Welsh, Aldo A. Rossini and Dale L. Greiner

J Immunol February 1, 2006, 176 (3) 1561-1570; DOI: https://doi.org/10.4049/jimmunol.176.3.1561
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Tec Kinases Itk and Rlk Are Required for CD8⁺ T Cell Responses to Virus Infection Independent of Their Role in CD4⁺ T Cell Help
Luana O. Atherly, Michael A. Brehm, Raymond M. Welsh and Leslie J. Berg

J Immunol February 1, 2006, 176 (3) 1571-1581; DOI: https://doi.org/10.4049/jimmunol.176.3.1571
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CD4⁺CD25⁺ T Regulatory Cells Suppress NK Cell-Mediated Immunotherapy of Cancer
Mark J. Smyth, Michele W. L. Teng, Jeremy Swann, Konstantinos Kyparissoudis, Dale I. Godfrey and Yoshihiro Hayakawa

J Immunol February 1, 2006, 176 (3) 1582-1587; DOI: https://doi.org/10.4049/jimmunol.176.3.1582
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Brain-Derived Heat Shock Protein 70-Peptide Complexes Induce NK Cell-Dependent Tolerance to Experimental Autoimmune Encephalomyelitis
Grazyna Galazka, Mariusz Stasiolek, Agata Walczak, Anna Jurewicz, Alicja Zylicz, Celia F. Brosnan, Cedric S. Raine and Krzysztof W. Selmaj

J Immunol February 1, 2006, 176 (3) 1588-1599; DOI: https://doi.org/10.4049/jimmunol.176.3.1588
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Respiratory Syncytial Virus G Protein and G Protein CX3C Motif Adversely Affect CX3CR1⁺ T Cell Responses
Jennifer Harcourt, Rene Alvarez, Les P. Jones, Christine Henderson, Larry J. Anderson and Ralph A. Tripp

J Immunol February 1, 2006, 176 (3) 1600-1608; DOI: https://doi.org/10.4049/jimmunol.176.3.1600
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CD4⁺CD25⁺ Regulatory T Cells Inhibit the Antigen-Dependent Expansion of Self-Reactive T Cells In Vivo
Tricia D. Zwar, Simon Read, Ian R. van Driel and Paul A. Gleeson

J Immunol February 1, 2006, 176 (3) 1609-1617; DOI: https://doi.org/10.4049/jimmunol.176.3.1609
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MR1-Restricted Vα19i Mucosal-Associated Invariant T Cells Are Innate T Cells in the Gut Lamina Propria That Provide a Rapid and Diverse Cytokine Response
Izumi Kawachi, Jorge Maldonado, Carey Strader and Susan Gilfillan

J Immunol February 1, 2006, 176 (3) 1618-1627; DOI: https://doi.org/10.4049/jimmunol.176.3.1618
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Cross-Positive Selection of Thymocytes Expressing a Single TCR by Multiple Major Histocompatibility Complex Molecules of Both Classes: Implications for CD4⁺ versus CD8⁺ Lineage Commitment
Koji Eshima, Harumi Suzuki and Nobukata Shinohara

J Immunol February 1, 2006, 176 (3) 1628-1636; DOI: https://doi.org/10.4049/jimmunol.176.3.1628
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Early Autoimmune Destruction of Islet Grafts Is Associated with a Restricted Repertoire of IGRP-Specific CD8⁺ T Cells in Diabetic Nonobese Diabetic Mice
Carmen P. Wong, Li Li, Jeffrey A. Frelinger and Roland Tisch

J Immunol February 1, 2006, 176 (3) 1637-1644; DOI: https://doi.org/10.4049/jimmunol.176.3.1637
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NKT Cells and IFN-γ Establish the Regulatory Environment for the Control of Diabetogenic T Cells in the Nonobese Diabetic Mouse
Judith A. Cain, Judith A. Smith, Jennifer K. Ondr, Bo Wang and Jonathan D. Katz

J Immunol February 1, 2006, 176 (3) 1645-1654; DOI: https://doi.org/10.4049/jimmunol.176.3.1645

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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The Nucleotide Targets of Somatic Mutation and the Role of Selection in Immunoglobulin Heavy Chains of a Teleost Fish
Feixue Yang, Geoffrey C. Waldbieser and Craig J. Lobb

J Immunol February 1, 2006, 176 (3) 1655-1667; DOI: https://doi.org/10.4049/jimmunol.176.3.1655
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Phosphatidylinositol 3-Kinase Functions as a Ras Effector in the Signaling Cascade That Regulates Dephosphorylation of the Actin-Remodeling Protein Cofilin after Costimulation of Untransformed Human T Lymphocytes
Guido H. Wabnitz, Gabriele Nebl, Martin Klemke, Andreas J. Schröder and Yvonne Samstag

J Immunol February 1, 2006, 176 (3) 1668-1674; DOI: https://doi.org/10.4049/jimmunol.176.3.1668
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Opioids Trigger α₅β₁ Integrin-Mediated Monocyte Adhesion
Oscar M. Pello, Béatrice Duthey, David García-Bernal, José Miguel Rodríguez-Frade, Jens V. Stein, Joaquín Teixido, Carlos Martínez-A. and Mario Mellado

J Immunol February 1, 2006, 176 (3) 1675-1685; DOI: https://doi.org/10.4049/jimmunol.176.3.1675
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Characterization of Functional Oligosaccharide Mimics of the Shigella flexneri Serotype 2a O-Antigen: Implications for the Development of a Chemically Defined Glycoconjugate Vaccine
Armelle Phalipon, Corina Costachel, Cyrille Grandjean, Audrey Thuizat, Catherine Guerreiro, Myriam Tanguy, Farida Nato, Brigitte Vulliez-Le Normand, Frédéric Bélot, Karen Wright, Véronique Marcel-Peyre, Philippe J. Sansonetti and Laurence A. Mulard

J Immunol February 1, 2006, 176 (3) 1686-1694; DOI: https://doi.org/10.4049/jimmunol.176.3.1686
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Glucocorticoids Engage Different Signal Transduction Pathways to Induce Apoptosis in Thymocytes and Mature T Cells
Dapeng Wang, Nora Müller, Kirsty G. McPherson and Holger M. Reichardt

J Immunol February 1, 2006, 176 (3) 1695-1702; DOI: https://doi.org/10.4049/jimmunol.176.3.1695

HOST DEFENSE

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Qa-1^b and CD94-NKG2a Interaction Regulate Cytolytic Activity of Herpes Simplex Virus-Specific Memory CD8⁺ T Cells in the Latently Infected Trigeminal Ganglia
Susmit Suvas, Ahmet Kursat Azkur and Barry T. Rouse

J Immunol February 1, 2006, 176 (3) 1703-1711; DOI: https://doi.org/10.4049/jimmunol.176.3.1703
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Immunity and Tolerance to Aspergillus Involve Functionally Distinct Regulatory T Cells and Tryptophan Catabolism
Claudia Montagnoli, Francesca Fallarino, Roberta Gaziano, Silvia Bozza, Silvia Bellocchio, Teresa Zelante, Wiswanath P. Kurup, Lucia Pitzurra, Paolo Puccetti and Luigina Romani

J Immunol February 1, 2006, 176 (3) 1712-1723; DOI: https://doi.org/10.4049/jimmunol.176.3.1712
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Experimental African Trypanosomiasis: A Subset of Pathogenic, IFN-γ-Producing, MHC Class II-Restricted CD4⁺ T Cells Mediates Early Mortality in Highly Susceptible Mice
Meiqing Shi, Guojian Wei, Wanling Pan and Henry Tabel

J Immunol February 1, 2006, 176 (3) 1724-1732; DOI: https://doi.org/10.4049/jimmunol.176.3.1724
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Respiratory Syncytial Virus Induces TLR3 Protein and Protein Kinase R, Leading to Increased Double-Stranded RNA Responsiveness in Airway Epithelial Cells
Dayna J. Groskreutz, Martha M. Monick, Linda S. Powers, Timur O. Yarovinsky, Dwight C. Look and Gary W. Hunninghake

J Immunol February 1, 2006, 176 (3) 1733-1740; DOI: https://doi.org/10.4049/jimmunol.176.3.1733
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DC-SIGN Is a Receptor for Human Herpesvirus 8 on Dendritic Cells and Macrophages
Giovanna Rappocciolo, Frank J. Jenkins, Heather R. Hensler, Paolo Piazza, Mariel Jais, Luann Borowski, Simon C. Watkins and Charles R. Rinaldo Jr

J Immunol February 1, 2006, 176 (3) 1741-1749; DOI: https://doi.org/10.4049/jimmunol.176.3.1741
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CD25⁺ Regulatory T Cell Depletion Augments Immunotherapy of Micrometastases by an IL-21-Secreting Cellular Vaccine
Alberto Comes, Ombretta Rosso, Anna Maria Orengo, Emma Di Carlo, Carlo Sorrentino, Raffaella Meazza, Tiziana Piazza, Barbara Valzasina, Patrizia Nanni, Mario P. Colombo and Silvano Ferrini

J Immunol February 1, 2006, 176 (3) 1750-1758; DOI: https://doi.org/10.4049/jimmunol.176.3.1750
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Immunological Characterization and Antibacterial Function of Persisting Granulocytes in Leukemic Patients Receiving Pulse Cytosine Arabinoside-Consolidation Chemotherapy on Days 1, 3, and 5
Maria-T. Krauth, Stefan Florian, Alexandra Böhm, Karoline Sonneck, Hermine Agis, Puchit Samorapoompichit, Alexander W. Hauswirth, Wolfgang R. Sperr and Peter Valent

J Immunol February 1, 2006, 176 (3) 1759-1768; DOI: https://doi.org/10.4049/jimmunol.176.3.1759
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Deficiency of Mannose-Binding Lectin Greatly Increases Susceptibility to Postburn Infection with Pseudomonas aeruginosa
Mette Møller-Kristensen, W. K. Eddie Ip, Lei Shi, Lakshmi D. Gowda, Michael R. Hamblin, Steffen Thiel, Jens Chr. Jensenius, R. Alan B. Ezekowitz and Kazue Takahashi

J Immunol February 1, 2006, 176 (3) 1769-1775; DOI: https://doi.org/10.4049/jimmunol.176.3.1769
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Bacillus anthracis Edema Toxin Acts as an Adjuvant for Mucosal Immune Responses to Nasally Administered Vaccine Antigens
Alexandra Duverger, Raymond J. Jackson, Frederick W. van Ginkel, Romy Fischer, Angela Tafaro, Stephen H. Leppla, Kohtaro Fujihashi, Hiroshi Kiyono, Jerry R. McGhee and Prosper N. Boyaka

J Immunol February 1, 2006, 176 (3) 1776-1783; DOI: https://doi.org/10.4049/jimmunol.176.3.1776
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Induction of Positive Cellular and Humoral Immune Responses by a Prime-Boost Vaccine Encoded with Simian Immunodeficiency Virus gag/pol
Kenji Someya, Yasushi Ami, Tadashi Nakasone, Yasuyuki Izumi, Kazuhiro Matsuo, Shigeo Horibata, Ke-Qin Xin, Hiroshi Yamamoto, Kenji Okuda, Naoki Yamamoto and Mitsuo Honda

J Immunol February 1, 2006, 176 (3) 1784-1795; DOI: https://doi.org/10.4049/jimmunol.176.3.1784
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Identification of Cross-Reactive Peptides Using Combinatorial Libraries Circumvents Tolerance against Her-2/neu-Immunodominant Epitope
Joseph Lustgarten, Ana L. Dominguez and Clemencia Pinilla

J Immunol February 1, 2006, 176 (3) 1796-1805; DOI: https://doi.org/10.4049/jimmunol.176.3.1796
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Human Macrophages Do Not Require Phagosome Acidification to Mediate Fungistatic/Fungicidal Activity against Histoplasma capsulatum
Simon L. Newman, Lisa Gootee, Jeremy Hilty and Randall E. Morris

J Immunol February 1, 2006, 176 (3) 1806-1813; DOI: https://doi.org/10.4049/jimmunol.176.3.1806
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Costimulation Requirements for Antiviral CD8⁺ T Cells Differ for Acute and Persistent Phases of Polyoma Virus Infection
Christopher C. Kemball, Eun D. Han Lee, Eva Szomolanyi-Tsuda, Thomas C. Pearson, Christian P. Larsen and Aron E. Lukacher

J Immunol February 1, 2006, 176 (3) 1814-1824; DOI: https://doi.org/10.4049/jimmunol.176.3.1814
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Inhibition of TCR Signaling by Herpes Simplex Virus
Derek D. Sloan, Jin-Young Han, Tracy K. Sandifer, Mary Stewart, Aaron J. Hinz, Miri Yoon, David C. Johnson, Patricia G. Spear and Keith R. Jerome

J Immunol February 1, 2006, 176 (3) 1825-1833; DOI: https://doi.org/10.4049/jimmunol.176.3.1825
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Mimicry of Apoptotic Cells by Exposing Phosphatidylserine Participates in the Establishment of Amastigotes of Leishmania (L) amazonensis in Mammalian Hosts
João L. M. Wanderley, Maria E. C. Moreira, Aline Benjamin, Adriana C. Bonomo and Marcello A. Barcinski

J Immunol February 1, 2006, 176 (3) 1834-1839; DOI: https://doi.org/10.4049/jimmunol.176.3.1834
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Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-γ Signaling
Stefan Zimmermann, Peter J. Murray, Klaus Heeg and Alexander H. Dalpke

J Immunol February 1, 2006, 176 (3) 1840-1847; DOI: https://doi.org/10.4049/jimmunol.176.3.1840

INFLAMMATION

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Anti-Inflammatory Actions of Neuroprotectin D1/Protectin D1 and Its Natural Stereoisomers: Assignments of Dihydroxy-Containing Docosatrienes
Charles N. Serhan, Katherine Gotlinger, Song Hong, Yan Lu, Jeffrey Siegelman, Tamara Baer, Rong Yang, Sean P. Colgan and Nicos A. Petasis

J Immunol February 1, 2006, 176 (3) 1848-1859; DOI: https://doi.org/10.4049/jimmunol.176.3.1848
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Fraktalkine Produced by Airway Smooth Muscle Cells Contributes to Mast Cell Recruitment in Asthma
Amr El-Shazly, Patrick Berger, Pierre-Olivier Girodet, Olga Ousova, Michael Fayon, Jean-Marc Vernejoux, Roger Marthan and J. Manuel Tunon-de-Lara

J Immunol February 1, 2006, 176 (3) 1860-1868; DOI: https://doi.org/10.4049/jimmunol.176.3.1860
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Corticotropin-Releasing Factor and the Urocortins Induce the Expression of TLR4 in Macrophages via Activation of the Transcription Factors PU.1 and AP-1
Christos Tsatsanis, Ariadne Androulidaki, Themis Alissafi, Ioannis Charalampopoulos, Erini Dermitzaki, Thierry Roger, Achille Gravanis and Andrew N. Margioris

J Immunol February 1, 2006, 176 (3) 1869-1877; DOI: https://doi.org/10.4049/jimmunol.176.3.1869
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Lipoxin A₄ Redistributes Myosin IIA and Cdc42 in Macrophages: Implications for Phagocytosis of Apoptotic Leukocytes
Keira Reville, John K. Crean, Sharon Vivers, Ian Dransfield and Catherine Godson

J Immunol February 1, 2006, 176 (3) 1878-1888; DOI: https://doi.org/10.4049/jimmunol.176.3.1878
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Proinflammatory Effects of Tweak/Fn14 Interactions in Glomerular Mesangial Cells
Sean Campbell, Linda C. Burkly, Hua-Xin Gao, Joan W. Berman, Lihe Su, Beth Browning, Timothy Zheng, Lena Schiffer, Jennifer S. Michaelson and Chaim Putterman

J Immunol February 1, 2006, 176 (3) 1889-1898; DOI: https://doi.org/10.4049/jimmunol.176.3.1889
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Essential Role of MAPK Phosphatase-1 in the Negative Control of Innate Immune Responses
Konstantin V. Salojin, Iris B. Owusu, Karen A. Millerchip, Mark Potter, Ken A. Platt and Tamas Oravecz

J Immunol February 1, 2006, 176 (3) 1899-1907; DOI: https://doi.org/10.4049/jimmunol.176.3.1899
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In Vitro and In Situ Expression of IL-23 by Keratinocytes in Healthy Skin and Psoriasis Lesions: Enhanced Expression in Psoriatic Skin
Gamze Piskin, Regien M. R. Sylva-Steenland, Jan D. Bos and Marcel B. M. Teunissen

J Immunol February 1, 2006, 176 (3) 1908-1915; DOI: https://doi.org/10.4049/jimmunol.176.3.1908
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Circulating Progenitor Epithelial Cells Traffic via CXCR4/CXCL12 in Response to Airway Injury
Brigitte N. Gomperts, John A. Belperio, P. Nagesh Rao, Scott H. Randell, Michael C. Fishbein, Marie D. Burdick and Robert M. Strieter

J Immunol February 1, 2006, 176 (3) 1916-1927; DOI: https://doi.org/10.4049/jimmunol.176.3.1916
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Suppression of Discoidin Domain Receptor 1 by RNA Interference Attenuates Lung Inflammation
Wataru Matsuyama, Masaki Watanabe, Yuko Shirahama, Ryuki Hirano, Hideo Mitsuyama, Ikkou Higashimoto, Mistuhiro Osame and Kimiyoshi Arimura

J Immunol February 1, 2006, 176 (3) 1928-1936; DOI: https://doi.org/10.4049/jimmunol.176.3.1928
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Deletion of TLR3 Alters the Pulmonary Immune Environment and Mucus Production during Respiratory Syncytial Virus Infection
Brian D. Rudd, Jetse J. Smit, Richard A. Flavell, Lena Alexopoulou, Matthew A. Schaller, Achim Gruber, Aaron A. Berlin and Nicholas W. Lukacs

J Immunol February 1, 2006, 176 (3) 1937-1942; DOI: https://doi.org/10.4049/jimmunol.176.3.1937
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Inhibition of Chronic Airway Inflammation and Remodeling by Galectin-3 Gene Therapy in a Murine Model
Esther López, Victoria del Pozo, Teresa Miguel, Beatriz Sastre, Carmen Seoane, Esther Civantos, Elena Llanes, M. Luisa Baeza, Pilar Palomino, Blanca Cárdaba, Soledad Gallardo, Félix Manzarbeitia, José M. Zubeldia and Carlos Lahoz

J Immunol February 1, 2006, 176 (3) 1943-1950; DOI: https://doi.org/10.4049/jimmunol.176.3.1943

CLINICAL IMMUNOLOGY

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Redundancy in Antigen-Presenting Function of the HLA-DR and -DQ Molecules in the Multiple Sclerosis-Associated HLA-DR2 Haplotype
Mireia Sospedra, Paolo A. Muraro, Irena Stefanová, Yingdong Zhao, Katherine Chung, Yili Li, Marc Giulianotti, Richard Simon, Roy Mariuzza, Clemencia Pinilla and Roland Martin

J Immunol February 1, 2006, 176 (3) 1951-1961; DOI: https://doi.org/10.4049/jimmunol.176.3.1951
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Effacing of the T Cell Compartment by Cardiac Transplantation in Infancy
Brenda M. Ogle, Lori J. West, David J. Driscoll, Scott E. Strome, Raymund R. Razonable, Carlos V. Paya, Marilia Cascalho and Jeffrey L. Platt

J Immunol February 1, 2006, 176 (3) 1962-1967; DOI: https://doi.org/10.4049/jimmunol.176.3.1962
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Identification of an Epitope within Human Integrin α₆ Subunit for the Binding of Autoantibody and Its Role in Basement Membrane Separation in Oral Pemphigoid
Khwaja Aftab Rashid, Joel N. H. Stern and A. Razzaque Ahmed

J Immunol February 1, 2006, 176 (3) 1968-1977; DOI: https://doi.org/10.4049/jimmunol.176.3.1968
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TLR9 Activation Is Defective in Common Variable Immune Deficiency
Charlotte Cunningham-Rundles, Lin Radigan, Adina K. Knight, Li Zhang, Laura Bauer and Atsushi Nakazawa

J Immunol February 1, 2006, 176 (3) 1978-1987; DOI: https://doi.org/10.4049/jimmunol.176.3.1978
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Allelic Variation in Key Peptide-Binding Pockets Discriminates between Closely Related Diabetes-Protective and Diabetes-Susceptible HLA-DQB1*06 Alleles
Ruth A. Ettinger, George K. Papadopoulos, Antonis K. Moustakas, Gerald T. Nepom and William W. Kwok

J Immunol February 1, 2006, 176 (3) 1988-1998; DOI: https://doi.org/10.4049/jimmunol.176.3.1988
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Predicting Tumor Outcome following Cancer Vaccination by Monitoring Quantitative and Qualitative CD8⁺ T Cell Parameters
Antonio Rosato, Alessia Zoso, Silvia Dalla Santa, Gabriella Milan, Paola Del Bianco, Gian Luca De Salvo and Paola Zanovello

J Immunol February 1, 2006, 176 (3) 1999-2006; DOI: https://doi.org/10.4049/jimmunol.176.3.1999
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Pretreatment Intracerebral and Peripheral Blood Immune Responses in Vietnamese Adults with Tuberculous Meningitis: Diagnostic Value and Relationship to Disease Severity and Outcome
Cameron P. Simmons, Guy E. Thwaites, Nguyen Than Ha Quyen, Estee Torok, Dang Minh Hoang, Tran Thi Hong Chau, Pham Phuong Mai, Nguyen Thi Ngoc Lan, Nguyen Huy Dung, Hoang Thi Quy, Nguyen Duc Bang, Tran Tinh Hien and Jeremy Farrar

J Immunol February 1, 2006, 176 (3) 2007-2014; DOI: https://doi.org/10.4049/jimmunol.176.3.2007
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Autoreactive T and B Cells from Bullous Pemphigoid (BP) Patients Recognize Epitopes Clustered in Distinct Regions of BP180 and BP230
Sybille Thoma-Uszynski, Wolfgang Uter, Susanne Schwietzke, Gerold Schuler, Luca Borradori and Michael Hertl

J Immunol February 1, 2006, 176 (3) 2015-2023; DOI: https://doi.org/10.4049/jimmunol.176.3.2015

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