Skip to main content

Main menu

  • Home
  • Articles
    • Current Issue
    • Next in The JI
    • Archive
    • Brief Reviews
      • Neuroimmunology: To Sense and Protect
    • Pillars of Immunology
    • Translating Immunology
    • Most Read
    • Top Downloads
    • Annual Meeting Abstracts
  • COVID-19/SARS/MERS Articles
  • Info
    • About the Journal
    • For Authors
    • Journal Policies
    • Influence Statement
    • For Advertisers
  • Editors
  • Submit
    • Submit a Manuscript
    • Instructions for Authors
    • Journal Policies
  • Subscribe
    • Journal Subscriptions
    • Email Alerts
    • RSS Feeds
    • ImmunoCasts
  • More
    • Most Read
    • Most Cited
    • ImmunoCasts
    • AAI Disclaimer
    • Feedback
    • Help
    • Accessibility Statement
  • Other Publications
    • American Association of Immunologists
    • ImmunoHorizons

User menu

  • Subscribe
  • Log in

Search

  • Advanced search
The Journal of Immunology
  • Other Publications
    • American Association of Immunologists
    • ImmunoHorizons
  • Subscribe
  • Log in
The Journal of Immunology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Next in The JI
    • Archive
    • Brief Reviews
    • Pillars of Immunology
    • Translating Immunology
    • Most Read
    • Top Downloads
    • Annual Meeting Abstracts
  • COVID-19/SARS/MERS Articles
  • Info
    • About the Journal
    • For Authors
    • Journal Policies
    • Influence Statement
    • For Advertisers
  • Editors
  • Submit
    • Submit a Manuscript
    • Instructions for Authors
    • Journal Policies
  • Subscribe
    • Journal Subscriptions
    • Email Alerts
    • RSS Feeds
    • ImmunoCasts
  • More
    • Most Read
    • Most Cited
    • ImmunoCasts
    • AAI Disclaimer
    • Feedback
    • Help
    • Accessibility Statement
  • Follow The Journal of Immunology on Twitter
  • Follow The Journal of Immunology on RSS

2B4/CD48-Mediated Regulation of Lymphocyte Activation and Function

Erika Assarsson, Taku Kambayashi, Catrine M. Persson, Benedict J. Chambers and Hans-Gustaf Ljunggren
J Immunol August 15, 2005, 175 (4) 2045-2049; DOI: https://doi.org/10.4049/jimmunol.175.4.2045
Erika Assarsson
*Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden;
†Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, San Diego, CA 92122; and
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Taku Kambayashi
‡Department of Pathology, University of Pennsylvania, Philadelphia, PA 19104
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Catrine M. Persson
*Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Benedict J. Chambers
*Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hans-Gustaf Ljunggren
*Department of Medicine, Center for Infectious Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Article Figures & Data

Figures

  • FIGURE 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIGURE 1.

    Principles of 2B4-CD48 interactions. a, 2B4 acts as a stimulatory/costimulatory receptor upon interactions with CD48 on the neighboring cell. b, 2B4 acts as an inhibitory receptor upon interactions with CD48 on the neighboring cell. c, CD48 acts as a stimulatory/costimulatory receptor upon interacting with 2B4 on the neighboring cell. 2B4 (red, transmembrane), CD48 (green, GPI linked). +, Stimulation/costimulation; −, inhibition.

PreviousNext
Back to top

In this issue

The Journal of Immunology: 175 (4)
The Journal of Immunology
Vol. 175, Issue 4
15 Aug 2005
  • Table of Contents
  • About the Cover
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word about The Journal of Immunology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
2B4/CD48-Mediated Regulation of Lymphocyte Activation and Function
(Your Name) has forwarded a page to you from The Journal of Immunology
(Your Name) thought you would like to see this page from the The Journal of Immunology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
2B4/CD48-Mediated Regulation of Lymphocyte Activation and Function
Erika Assarsson, Taku Kambayashi, Catrine M. Persson, Benedict J. Chambers, Hans-Gustaf Ljunggren
The Journal of Immunology August 15, 2005, 175 (4) 2045-2049; DOI: 10.4049/jimmunol.175.4.2045

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
2B4/CD48-Mediated Regulation of Lymphocyte Activation and Function
Erika Assarsson, Taku Kambayashi, Catrine M. Persson, Benedict J. Chambers, Hans-Gustaf Ljunggren
The Journal of Immunology August 15, 2005, 175 (4) 2045-2049; DOI: 10.4049/jimmunol.175.4.2045
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like

Jump to section

  • Article
    • Abstract
    • Expression of 2B4 and its interaction with CD48
    • Activating and inhibitory functions of the 2B4 receptor
    • Signal transduction through 2B4
    • T cells costimulate each other through 2B4-CD48 interactions
    • NK cells costimulate each other through 2B4-CD48 interactions
    • NK cells costimulate T cells through 2B4-CD48 interactions
    • Conclusions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Coronavirus Receptors as Immune Modulators
  • Systems Approaches to Unravel T Cell Function and Therapeutic Potential in Autoimmune Disease
  • The Ugly Duckling Turned to Swan: A Change in Perception of Bystander-Activated Memory CD8 T Cells
Show more BRIEF REVIEWS

Similar Articles

Navigate

  • Home
  • Current Issue
  • Next in The JI
  • Archive
  • Brief Reviews
  • Pillars of Immunology
  • Translating Immunology

For Authors

  • Submit a Manuscript
  • Instructions for Authors
  • About the Journal
  • Journal Policies
  • Editors

General Information

  • Advertisers
  • Subscribers
  • Rights and Permissions
  • Accessibility Statement
  • Public Access
  • Privacy Policy
  • Disclaimer

Journal Services

  • Email Alerts
  • RSS Feeds
  • ImmunoCasts
  • Twitter

Copyright © 2021 by The American Association of Immunologists, Inc.

Print ISSN 0022-1767        Online ISSN 1550-6606