On the cover: Identification of high and low responders to LPS. LPS-induced production of seven different cytokines in whole blood of 102 individuals, ex vivo, is shown ranked from lowest (bottom) to highest (top) with each individual represented by one line. High responders (yellow lines) and low responders (red lines) are highlighted. Wurfel, M. M., W. Y. Park, F. Radella, J. Ruzinski, A. Sandstrom, J. Strout, R. E. Bumgarner, and T. R. Martin. 2005. Identification of high and low responders to lipopolysaccharide in normal subjects: an unbiased approach to identify modulators of innate immunity. J. Immunol. 175: 2570–2578.