The Journal of Immunology: 175 (2)

July 15, 2005; Volume 175,Issue 2

IN THIS ISSUE

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IN THIS ISSUE

J Immunol July 15, 2005, 175 (2) 631-632; DOI: https://doi.org/10.4049/jimmunol.175.2.631

BRIEF REVIEW

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DNA Vaccines: Progress and Challenges
John J. Donnelly, Britta Wahren and Margaret A. Liu

J Immunol July 15, 2005, 175 (2) 633-639; DOI: https://doi.org/10.4049/jimmunol.175.2.633

CUTTING EDGE

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Cutting Edge: IL-12 Induces CD4⁺CD25⁻ T Cell Activation in the Presence of T Regulatory Cells
Irah L. King and Benjamin M. Segal

J Immunol July 15, 2005, 175 (2) 641-645; DOI: https://doi.org/10.4049/jimmunol.175.2.641

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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E2F1 and E2F2 Are Differentially Required for Homeostasis-Driven and Antigen-Induced T Cell Proliferation In Vivo
Deborah DeRyckere and James DeGregori

J Immunol July 15, 2005, 175 (2) 647-655; DOI: https://doi.org/10.4049/jimmunol.175.2.647
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Active Ca²⁺/Calmodulin-Dependent Protein Kinase IIγB Impairs Positive Selection of T Cells by Modulating TCR Signaling
Maureen A. McGargill, Leslie L. Sharp, Jack D. Bui, Stephen M. Hedrick and Sébastien Calbo

J Immunol July 15, 2005, 175 (2) 656-664; DOI: https://doi.org/10.4049/jimmunol.175.2.656
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Mechanisms of the Antitumor Responses and Host-versus-Graft Reactions Induced by Recipient Leukocyte Infusions in Mixed Chimeras Prepared with Nonmyeloablative Conditioning: A Critical Role for Recipient CD4⁺ T Cells and Recipient Leukocyte Infusion-Derived IFN-γ-Producing CD8⁺ T Cells
Marie-Therese Rubio, Toshiki I. Saito, Kristin Kattleman, Guiling Zhao, Jennifer Buchli and Megan Sykes

J Immunol July 15, 2005, 175 (2) 665-676; DOI: https://doi.org/10.4049/jimmunol.175.2.665
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Induction of a Regulatory Phenotype in Human CD4⁺ T Cells by Streptococcal M Protein
Jeffrey D. Price, Jessica Schaumburg, Charlotta Sandin, John P. Atkinson, Gunnar Lindahl and Claudia Kemper

J Immunol July 15, 2005, 175 (2) 677-684; DOI: https://doi.org/10.4049/jimmunol.175.2.677
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The Synthetic Peptide Trp-Lys-Tyr-Met-Val-D-Met Inhibits Human Monocyte-Derived Dendritic Cell Maturation via Formyl Peptide Receptor and Formyl Peptide Receptor-Like 2
Hyun Kyu Kang, Ha-Young Lee, Mi-Kyoung Kim, Kyoung Sun Park, Yeong Min Park, Jong-Young Kwak and Yoe-Sik Bae

J Immunol July 15, 2005, 175 (2) 685-692; DOI: https://doi.org/10.4049/jimmunol.175.2.685
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In Vivo Hydrodynamic Delivery of cDNA Encoding IL-2: Rapid, Sustained Redistribution, Activation of Mouse NK Cells, and Therapeutic Potential in the Absence of NKT Cells
John R. Ortaldo, Robin T. Winkler-Pickett, Earl W. Bere Jr, Morihiro Watanabe, William J. Murphy and Robert H. Wiltrout

J Immunol July 15, 2005, 175 (2) 693-699; DOI: https://doi.org/10.4049/jimmunol.175.2.693
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Inefficient Cross-Presentation Limits the CD8⁺ T Cell Response to a Subdominant Tumor Antigen Epitope
Pavel Otahal, Sandra C. Hutchinson, Lawrence M. Mylin, M. Judith Tevethia, Satvir S. Tevethia and Todd D. Schell

J Immunol July 15, 2005, 175 (2) 700-712; DOI: https://doi.org/10.4049/jimmunol.175.2.700
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The Type 1 Cysteinyl Leukotriene Receptor Triggers Calcium Influx and Chemotaxis in Mouse αβ- and γδ Effector T Cells
Immo Prinz, Claude Gregoire, Hans Mollenkopf, Enrique Aguado, Ying Wang, Marie Malissen, Stefan H.E. Kaufmann and Bernard Malissen

J Immunol July 15, 2005, 175 (2) 713-719; DOI: https://doi.org/10.4049/jimmunol.175.2.713
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Systemic NKG2D Down-Regulation Impairs NK and CD8 T Cell Responses In Vivo
Katrin Wiemann, Hans-Willi Mittrücker, Ute Feger, Stefan A. Welte, Wayne M. Yokoyama, Thomas Spies, Hans-Georg Rammensee and Alexander Steinle

J Immunol July 15, 2005, 175 (2) 720-729; DOI: https://doi.org/10.4049/jimmunol.175.2.720
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Bordetella pertussis Adenylate Cyclase Toxin Modulates Innate and Adaptive Immune Responses: Distinct Roles for Acylation and Enzymatic Activity in Immunomodulation and Cell Death
Aoife P. Boyd, Pádraig J. Ross, Helen Conroy, Nicola Mahon, Ed C. Lavelle and Kingston H. G. Mills

J Immunol July 15, 2005, 175 (2) 730-738; DOI: https://doi.org/10.4049/jimmunol.175.2.730
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Phenotype and Homing of CD4 Tumor-Specific T Cells Is Modulated by Tumor Bulk
Fabio Benigni, Valérie S. Zimmermann, Stephanie Hugues, Stefano Caserta, Veronica Basso, Laura Rivino, Elizabeth Ingulli, Laurent Malherbe, Nicolas Glaichenhaus and Anna Mondino

J Immunol July 15, 2005, 175 (2) 739-748; DOI: https://doi.org/10.4049/jimmunol.175.2.739
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Phospholipase C-γ2 Is a Critical Signaling Mediator for Murine NK Cell Activating Receptors
Ilaria Tassi, Rachel Presti, Sungjin Kim, Wayne M. Yokoyama, Susan Gilfillan and Marco Colonna

J Immunol July 15, 2005, 175 (2) 749-754; DOI: https://doi.org/10.4049/jimmunol.175.2.749
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IL-21 Sustains CD28 Expression on IL-15-Activated Human Naive CD8⁺ T Cells
Nuno L. Alves, Fernando A. Arosa and René A. W. van Lier

J Immunol July 15, 2005, 175 (2) 755-762; DOI: https://doi.org/10.4049/jimmunol.175.2.755
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Expansion and Hyperactivity of CD1d-Restricted NKT Cells during the Progression of Systemic Lupus Erythematosus in (New Zealand Black × New Zealand White)F₁ Mice
Claire Forestier, Alberto Molano, Jin Seon Im, Yves Dutronc, Betty Diamond, Anne Davidson, Petr A. Illarionov, Gurdyal S. Besra and Steven A. Porcelli

J Immunol July 15, 2005, 175 (2) 763-770; DOI: https://doi.org/10.4049/jimmunol.175.2.763
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Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation
Sergio A. Quezada, Kathy Bennett, Bruce R. Blazar, Alexander Y. Rudensky, Shimon Sakaguchi and Randolph J. Noelle

J Immunol July 15, 2005, 175 (2) 771-779; DOI: https://doi.org/10.4049/jimmunol.175.2.771
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Mechanisms of Gene Therapy for Tolerance: B7 Signaling Is Required for Peptide-IgG Gene-Transferred Tolerance Induction
Mary T. Litzinger, Yan Su, Tie Chi Lei, Nadejda Soukhareva and David W. Scott

J Immunol July 15, 2005, 175 (2) 780-787; DOI: https://doi.org/10.4049/jimmunol.175.2.780
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IL-23 Compensates for the Absence of IL-12p70 and Is Essential for the IL-17 Response during Tuberculosis but Is Dispensable for Protection and Antigen-Specific IFN-γ Responses if IL-12p70 Is Available
Shabaana A. Khader, John E. Pearl, Kaori Sakamoto, Leigh Gilmartin, Guy K. Bell, Dawn M. Jelley-Gibbs, Nico Ghilardi, Fred deSauvage and Andrea M. Cooper

J Immunol July 15, 2005, 175 (2) 788-795; DOI: https://doi.org/10.4049/jimmunol.175.2.788
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Cross-Presentation of the Long-Lived Lymphocytic Choriomeningitis Virus Nucleoprotein Does Not Require Neosynthesis and Is Enhanced via Heat Shock Proteins
Sameh Basta, Ricarda Stoessel, Michael Basler, Maries van den Broek and Marcus Groettrup

J Immunol July 15, 2005, 175 (2) 796-805; DOI: https://doi.org/10.4049/jimmunol.175.2.796
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Nitric Oxide Inhibits IFN-α Production of Human Plasmacytoid Dendritic Cells Partly via a Guanosine 3′,5′-Cyclic Monophosphate-Dependent Pathway
Rimpei Morita, Takashi Uchiyama and Toshiyuki Hori

J Immunol July 15, 2005, 175 (2) 806-812; DOI: https://doi.org/10.4049/jimmunol.175.2.806
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Cyclooxygenase 2 Inhibition Promotes IFN-γ-Dependent Enhancement of Antitumor Responses
Sherven Sharma, Li Zhu, Seok Chul Yang, Ling Zhang, Jeff Lin, Sven Hillinger, Brian Gardner, Karen Reckamp, Robert M. Strieter, Min Huang, Raj K. Batra and Steven M. Dubinett

J Immunol July 15, 2005, 175 (2) 813-819; DOI: https://doi.org/10.4049/jimmunol.175.2.813
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Dendritic Cell-Mediated Cross-Presentation of Antigens Derived from Colon Carcinoma Cells Exposed to a Highly Cytotoxic Multidrug Regimen with Gemcitabine, Oxaliplatin, 5-Fluorouracil, and Leucovorin, Elicits a Powerful Human Antigen-Specific CTL Response with Antitumor Activity in Vitro
Pierpaolo Correale, Maria Grazia Cusi, Maria Teresa Del Vecchio, Angelo Aquino, Salvatore Prete, Kwong Y. Tsang, Lucia Micheli, Cristina Nencini, Marco La Placa, Francesco Montagnani, Chiara Terrosi, Michele Caraglia, Vincenzo Formica, Giorgio Giorgi, Enzo Bonmassar and Guido Francini

J Immunol July 15, 2005, 175 (2) 820-828; DOI: https://doi.org/10.4049/jimmunol.175.2.820
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Orally Tolerized T Cells Can Form Conjugates with APCs but Are Defective in Immunological Synapse Formation
Wataru Ise, Kentaro Nakamura, Nobuko Shimizu, Hirofumi Goto, Kenichiro Fujimoto, Shuichi Kaminogawa and Satoshi Hachimura

J Immunol July 15, 2005, 175 (2) 829-838; DOI: https://doi.org/10.4049/jimmunol.175.2.829
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TLR4 and Toll-IL-1 Receptor Domain-Containing Adapter-Inducing IFN-β, but Not MyD88, Regulate Escherichia coli-Induced Dendritic Cell Maturation and Apoptosis In Vivo
Carl De Trez, Bernard Pajak, Maryse Brait, Nicolas Glaichenhaus, Jacques Urbain, Muriel Moser, Grégoire Lauvau and Eric Muraille

J Immunol July 15, 2005, 175 (2) 839-846; DOI: https://doi.org/10.4049/jimmunol.175.2.839
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Enhanced Antibacterial Potential in UBP43-Deficient Mice against Salmonella typhimurium Infection by Up-Regulating Type I IFN Signaling
Keun Il Kim, Oxana A. Malakhova, Kasper Hoebe, Ming Yan, Bruce Beutler and Dong-Er Zhang

J Immunol July 15, 2005, 175 (2) 847-854; DOI: https://doi.org/10.4049/jimmunol.175.2.847
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Antigen Presentation by an Immature Myeloid Dendritic Cell Line Does Not Cause CTL Deletion In Vivo, but Generates CD8⁺ Central Memory-Like T Cells That Can Be Rescued for Full Effector Function
Hélène Dumortier, Geertje J. D. van Mierlo, Deirdre Egan, Willem van Ewijk, René E. M. Toes, Rienk Offringa and Cornelis J. M. Melief

J Immunol July 15, 2005, 175 (2) 855-863; DOI: https://doi.org/10.4049/jimmunol.175.2.855
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T Cell Leukemia-1 Modulates TCR Signal Strength and IFN-γ Levels through Phosphatidylinositol 3-Kinase and Protein Kinase C Pathway Activation
Katrina K. Hoyer, Marco Herling, Ksenia Bagrintseva, David W. Dawson, Samuel W. French, Mathilde Renard, Jason G. Weinger, Dan Jones and Michael A. Teitell

J Immunol July 15, 2005, 175 (2) 864-873; DOI: https://doi.org/10.4049/jimmunol.175.2.864
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CCR2 and CCR6, but Not Endothelial Selectins, Mediate the Accumulation of Immature Dendritic Cells within the Lungs of Mice in Response to Particulate Antigen
John J. Osterholzer, Theresa Ames, Timothy Polak, Joanne Sonstein, Bethany B. Moore, Stephen W. Chensue, Galen B. Toews and Jeffrey L. Curtis

J Immunol July 15, 2005, 175 (2) 874-883; DOI: https://doi.org/10.4049/jimmunol.175.2.874
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Regulation of Follicular Dendritic Cell Networks by Activated T Cells: The Role of CD137 Signaling
Yonglian Sun, Sarah E. Blink, Jonathan H. Chen and Yang-Xin Fu

J Immunol July 15, 2005, 175 (2) 884-890; DOI: https://doi.org/10.4049/jimmunol.175.2.884
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Dendritic Cell Aggresome-Like-Induced Structure Formation and Delayed Antigen Presentation Coincide in Influenza Virus-Infected Dendritic Cells
Sylvia Herter, Philipp Osterloh, Norbert Hilf, Gerd Rechtsteiner, Jörg Höhfeld, Hans-Georg Rammensee and Hansjörg Schild

J Immunol July 15, 2005, 175 (2) 891-898; DOI: https://doi.org/10.4049/jimmunol.175.2.891
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NKT Cells Are Critical for the Initiation of an Inflammatory Bowel Response against Toxoplasma gondii
Catherine Ronet, Sylvie Darche, Maria Leite de Moraes, Sachiko Miyake, Takashi Yamamura, Jacques A. Louis, Lloyd H. Kasper and Dominique Buzoni-Gatel

J Immunol July 15, 2005, 175 (2) 899-908; DOI: https://doi.org/10.4049/jimmunol.175.2.899
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In Vivo Assessment of the Relative Contributions of Deletion, Anergy, and Editing to B Cell Self-Tolerance
Keli L. Hippen, Brian R. Schram, Lina E. Tze, Kathryn A. Pape, Marc K. Jenkins and Timothy W. Behrens

J Immunol July 15, 2005, 175 (2) 909-916; DOI: https://doi.org/10.4049/jimmunol.175.2.909
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IL-4 Inhibits Bone-Resorbing Activity of Mature Osteoclasts by Affecting NF-κB and Ca²⁺ Signaling
Latha S. Mangashetti, Shruti M. Khapli and Mohan R. Wani

J Immunol July 15, 2005, 175 (2) 917-925; DOI: https://doi.org/10.4049/jimmunol.175.2.917
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Regulation of LFA-1 Activity through Cytoskeleton Remodeling and Signaling Components Modulates the Efficiency of HIV Type-1 Entry in Activated CD4⁺ T Lymphocytes
Mélanie R. Tardif and Michel J. Tremblay

J Immunol July 15, 2005, 175 (2) 926-935; DOI: https://doi.org/10.4049/jimmunol.175.2.926
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Genetic Dissection of the Murine Lupus Susceptibility Locus Sle2: Contributions to Increased Peritoneal B-1a Cells and Lupus Nephritis Map to Different Loci
Zhiwei Xu, Biyan Duan, Byron P. Croker, Edward K. Wakeland and Laurence Morel

J Immunol July 15, 2005, 175 (2) 936-943; DOI: https://doi.org/10.4049/jimmunol.175.2.936
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Failure of CD25⁺ T Cells from Lupus-Prone Mice to Suppress Lupus Glomerulonephritis and Sialoadenitis
Harini Bagavant and Kenneth S. K. Tung

J Immunol July 15, 2005, 175 (2) 944-950; DOI: https://doi.org/10.4049/jimmunol.175.2.944
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Restraint of B Cell Activation by Foxj1-Mediated Antagonism of NF-κB and IL-6
Ling Lin, Steven L. Brody and Stanford L. Peng

J Immunol July 15, 2005, 175 (2) 951-958; DOI: https://doi.org/10.4049/jimmunol.175.2.951
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Lipopolysaccharide Injection Induces Relapses of Experimental Autoimmune Encephalomyelitis in Nontransgenic Mice via Bystander Activation of Autoreactive CD4⁺ Cells
Axel Nogai, Volker Siffrin, Kerstin Bonhagen, Caspar F. Pfueller, Thordis Hohnstein, Rudolf Volkmer-Engert, Wolfgang Brück, Christine Stadelmann and Thomas Kamradt

J Immunol July 15, 2005, 175 (2) 959-966; DOI: https://doi.org/10.4049/jimmunol.175.2.959

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Calnexin and ERp57 Facilitate the Assembly of the Neonatal Fc Receptor for IgG with β₂-Microglobulin in the Endoplasmic Reticulum
Xiaoping Zhu, Junmin Peng, Daohong Chen, Xindong Liu, Lilin Ye, Hideki Iijima, Kumar Kadavil, Wayne I. Lencer and Richard S. Blumberg

J Immunol July 15, 2005, 175 (2) 967-976; DOI: https://doi.org/10.4049/jimmunol.175.2.967
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Crystal Structure of Mouse CD1d Bound to the Self Ligand Phosphatidylcholine: A Molecular Basis for NKT Cell Activation
Barbara Giabbai, Stèphane Sidobre, M. D. Max Crispin, Yovan Sanchez-Ruìz, Angela Bachi, Mitchell Kronenberg, Ian A. Wilson and Massimo Degano

J Immunol July 15, 2005, 175 (2) 977-984; DOI: https://doi.org/10.4049/jimmunol.175.2.977
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Effects of Bcl-2 Levels on Fas Signaling-Induced Caspase-3 Activation: Molecular Genetic Tests of Computational Model Predictions
Fei Hua, Melanie G. Cornejo, Michael H. Cardone, Cynthia L. Stokes and Douglas A. Lauffenburger

J Immunol July 15, 2005, 175 (2) 985-995; DOI: https://doi.org/10.4049/jimmunol.175.2.985
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Hierarchical Regulation of CTLA-4 Dimer-Based Lattice Formation and Its Biological Relevance for T Cell Inactivation
Peter J. Darlington, Mark G. Kirchhof, Gabriel Criado, Jitin Sondhi and Joaquín Madrenas

J Immunol July 15, 2005, 175 (2) 996-1004; DOI: https://doi.org/10.4049/jimmunol.175.2.996
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Mutational Analysis of the Human 2B4 (CD244)/CD48 Interaction: Lys⁶⁸ and Glu⁷⁰ in the V Domain of 2B4 Are Critical for CD48 Binding and Functional Activation of NK Cells
Stephen O. Mathew, Pappanaicken R. Kumaresan, Jae Kyung Lee, Van T. Huynh and Porunelloor A. Mathew

J Immunol July 15, 2005, 175 (2) 1005-1013; DOI: https://doi.org/10.4049/jimmunol.175.2.1005
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Critical Role of the Fifth Domain of E-Cadherin for Heterophilic Adhesion with α_Eβ₇, But Not for Homophilic Adhesion
Kiyono Shiraishi, Kensei Tsuzaka, Keiko Yoshimoto, Chika Kumazawa, Kyoko Nozaki, Tohru Abe, Kazuo Tsubota and Tsutomu Takeuchi

J Immunol July 15, 2005, 175 (2) 1014-1021; DOI: https://doi.org/10.4049/jimmunol.175.2.1014
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Transcriptional Regulation of CD1D1 by Ets Family Transcription Factors
Yanbiao Geng, Peter Laslo, Kevin Barton and Chyung-Ru Wang

J Immunol July 15, 2005, 175 (2) 1022-1029; DOI: https://doi.org/10.4049/jimmunol.175.2.1022
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X Box-Like Sequences in the MHC Class II Region Maintain Regulatory Function
Jorge A. Gomez, Parimal Majumder, Uma M. Nagarajan and Jeremy M. Boss

J Immunol July 15, 2005, 175 (2) 1030-1040; DOI: https://doi.org/10.4049/jimmunol.175.2.1030
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Identification of a Macrophage-Specific Chromatin Signature in the IL-10 Locus
Margarida Saraiva, Jillian R. Christensen, Alla V. Tsytsykova, Anne E. Goldfeld, Steven C. Ley, Dimitris Kioussis and Anne O′Garra

J Immunol July 15, 2005, 175 (2) 1041-1046; DOI: https://doi.org/10.4049/jimmunol.175.2.1041
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Hepatocytes Express Abundant Surface Class I MHC and Efficiently Use Transporter Associated with Antigen Processing, Tapasin, and Low Molecular Weight Polypeptide Proteasome Subunit Components of Antigen Processing and Presentation Pathway
Ming Chen, Piotr Tabaczewski, Steven M. Truscott, Luc Van Kaer and Iwona Stroynowski

J Immunol July 15, 2005, 175 (2) 1047-1055; DOI: https://doi.org/10.4049/jimmunol.175.2.1047
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A Critical Role for Sialylation in Cryoglobulin Activity of Murine IgG3 Monoclonal Antibodies
Yasuhiro Kuroda, Aki Kuroki, Shuichi Kikuchi, Takaaki Funase, Munehiro Nakata and Shozo Izui

J Immunol July 15, 2005, 175 (2) 1056-1061; DOI: https://doi.org/10.4049/jimmunol.175.2.1056

IMMUNOGENETICS

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Epistatic Suppression of Systemic Lupus Erythematosus: Fine Mapping of Sles1 to Less Than 1 Mb
Srividya Subramanian, Young-Sun Yim, Kui Liu, Katalin Tus, Xin J. Zhou and Edward K. Wakeland

J Immunol July 15, 2005, 175 (2) 1062-1072; DOI: https://doi.org/10.4049/jimmunol.175.2.1062
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Multiple Germline κ Light Chains Generate Anti-Insulin B Cells in Nonobese Diabetic Mice
Emily J. Woodward and James W. Thomas

J Immunol July 15, 2005, 175 (2) 1073-1079; DOI: https://doi.org/10.4049/jimmunol.175.2.1073
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Several Genes Contribute to the Production of Autoreactive B and T Cells in the Murine Lupus Susceptibility Locus Sle1c
Yifang Chen, Daniel Perry, Susan A. Boackle, Eric S. Sobel, Hector Molina, Byron P. Croker and Laurence Morel

J Immunol July 15, 2005, 175 (2) 1080-1089; DOI: https://doi.org/10.4049/jimmunol.175.2.1080

HOST DEFENSE

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Reduced Three-Dimensional Motility in Dehydrated Airway Mucus Prevents Neutrophil Capture and Killing Bacteria on Airway Epithelial Surfaces
Hirotoshi Matsui, Margrith W. Verghese, Mehmet Kesimer, Ute E. Schwab, Scott H. Randell, John K. Sheehan, Barbara R. Grubb and Richard C. Boucher

J Immunol July 15, 2005, 175 (2) 1090-1099; DOI: https://doi.org/10.4049/jimmunol.175.2.1090
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Critical Role for the Oligoadenylate Synthetase/RNase L Pathway in Response to IFN-β during Acute Ocular Herpes Simplex Virus Type 1 Infection
Bobbie Ann Austin, Cassandra James, Robert H. Silverman and Daniel J. J. Carr

J Immunol July 15, 2005, 175 (2) 1100-1106; DOI: https://doi.org/10.4049/jimmunol.175.2.1100
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Long-Term Control of Mycobacterium tuberculosis Infection Is Mediated by Dynamic Immune Responses
Vanja Lazarevic, Dawn Nolt and JoAnne L. Flynn

J Immunol July 15, 2005, 175 (2) 1107-1117; DOI: https://doi.org/10.4049/jimmunol.175.2.1107
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Lentivirus Infection Causes Neuroinflammation and Neuronal Injury in Dorsal Root Ganglia: Pathogenic Effects of STAT-1 and Inducible Nitric Oxide Synthase
Yu Zhu, Gareth Jones, Shigeki Tsutsui, Wycliffe Opii, Shuhong Liu, Claudia Silva, D. Allan Butterfield and Christopher Power

J Immunol July 15, 2005, 175 (2) 1118-1126; DOI: https://doi.org/10.4049/jimmunol.175.2.1118
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Developmentally Regulated Intestinal Expression of IFN-γ and Its Target Genes and the Age-Specific Response to Enteric Salmonella Infection
Sue J. Rhee, W. Allan Walker and Bobby J. Cherayil

J Immunol July 15, 2005, 175 (2) 1127-1136; DOI: https://doi.org/10.4049/jimmunol.175.2.1127
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Invariant Vα14⁺ NKT Cells Participate in the Early Response to Enteric Listeria monocytogenes Infection
Thomas Ranson, Søren Bregenholt, Agnes Lehuen, Olivier Gaillot, Maria C. Leite-de-Moraes, André Herbelin, Patrick Berche and James P. Di Santo

J Immunol July 15, 2005, 175 (2) 1137-1144; DOI: https://doi.org/10.4049/jimmunol.175.2.1137
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Human Rhinoviruses Inhibit the Accessory Function of Dendritic Cells by Inducing Sialoadhesin and B7-H1 Expression
Stefanie Kirchberger, Otto Majdic, Peter Steinberger, Stefan Blüml, Katharina Pfistershammer, Gerhard Zlabinger, Luiza Deszcz, Ernst Kuechler, Walter Knapp and Johannes Stöckl

J Immunol July 15, 2005, 175 (2) 1145-1152; DOI: https://doi.org/10.4049/jimmunol.175.2.1145
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Immunoproteasome-Deficient Mice Mount Largely Normal CD8⁺ T Cell Responses to Lymphocytic Choriomeningitis Virus Infection and DNA Vaccination
Alexander K. Nussbaum, Maria P. Rodriguez-Carreno, Nicola Benning, Jason Botten and J. Lindsay Whitton

J Immunol July 15, 2005, 175 (2) 1153-1160; DOI: https://doi.org/10.4049/jimmunol.175.2.1153
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18β-Glycyrrhetinic Acid Triggers Curative Th1 Response and Nitric Oxide Up-Regulation in Experimental Visceral Leishmaniasis Associated with the Activation of NF-κB
Anindita Ukil, Aruna Biswas, Tapasi Das and Pijush K. Das

J Immunol July 15, 2005, 175 (2) 1161-1169; DOI: https://doi.org/10.4049/jimmunol.175.2.1161
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Diminished Expression and Function of TLR in Lymphatic Filariasis: A Novel Mechanism of Immune Dysregulation
Subash Babu, Carla P. Blauvelt, V. Kumaraswami and Thomas B. Nutman

J Immunol July 15, 2005, 175 (2) 1170-1176; DOI: https://doi.org/10.4049/jimmunol.175.2.1170
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Priming Effect of Lipopolysaccharide on Acetyl-Coenzyme A:Lyso-Platelet-Activating Factor Acetyltransferase Is MyD88 and TRIF Independent
Hideo Shindou, Satoshi Ishii, Masahiro Yamamoto, Kiyoshi Takeda, Shizuo Akira and Takao Shimizu

J Immunol July 15, 2005, 175 (2) 1177-1183; DOI: https://doi.org/10.4049/jimmunol.175.2.1177
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Induction of Humoral and CD8⁺ T Cell Responses Are Required for Protection against Lethal Ebola Virus Infection
Kelly L. Warfield, Gene Olinger, Emily M. Deal, Dana L. Swenson, Michael Bailey, Diane L. Negley, Mary Kate Hart and Sina Bavari

J Immunol July 15, 2005, 175 (2) 1184-1191; DOI: https://doi.org/10.4049/jimmunol.175.2.1184

INFLAMMATION

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An Intact Phosphocholine Binding Site Is Necessary for Transgenic Rabbit C-Reactive Protein to Protect Mice against Challenge with Platelet-Activating Factor
Steven Black, Augusta Wilson and David Samols

J Immunol July 15, 2005, 175 (2) 1192-1196; DOI: https://doi.org/10.4049/jimmunol.175.2.1192
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Macrophages Induce Invasiveness of Epithelial Cancer Cells Via NF-κB and JNK
Thorsten Hagemann, Julia Wilson, Hagen Kulbe, Ningfeng Fiona Li, David A. Leinster, Kellie Charles, Florian Klemm, Tobias Pukrop, Claudia Binder and Frances R. Balkwill

J Immunol July 15, 2005, 175 (2) 1197-1205; DOI: https://doi.org/10.4049/jimmunol.175.2.1197
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Alterations in Nitric Oxide and Cytokine Production with Airway Inflammation in the Absence of IL-10
Bill T. Ameredes, Ruben Zamora, Jigme M. Sethi, He-Liang Liu, Lauryn K. Kohut, Amber L. Gligonic, Augustine M. K. Choi and William J. Calhoun

J Immunol July 15, 2005, 175 (2) 1206-1213; DOI: https://doi.org/10.4049/jimmunol.175.2.1206
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Influence of β₁ Integrin Intracytoplasmic Domains in the Regulation of VLA-4-Mediated Adhesion of Human T Cells to VCAM-1 under Flow Conditions
Maria Alessandra Rosenthal-Allieri, Michel Ticchioni, Jean Philippe Breittmayer, Yoji Shimizu and Alain Bernard

J Immunol July 15, 2005, 175 (2) 1214-1223; DOI: https://doi.org/10.4049/jimmunol.175.2.1214
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Anti-Vascular Endothelial Growth Factor Gene Therapy Attenuates Lung Injury and Fibrosis in Mice
Naoki Hamada, Kazuyoshi Kuwano, Mizuho Yamada, Naoki Hagimoto, Kenichi Hiasa, Kensuke Egashira, Nobutaka Nakashima, Takashige Maeyama, Michihiro Yoshimi and Yoichi Nakanishi

J Immunol July 15, 2005, 175 (2) 1224-1231; DOI: https://doi.org/10.4049/jimmunol.175.2.1224
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Elimination of Senescent Neutrophils by TNF-Related Apoptosis-Inducing Ligand
Julian J. Lum, Gary Bren, Rebecca McClure and Andrew D. Badley

J Immunol July 15, 2005, 175 (2) 1232-1238; DOI: https://doi.org/10.4049/jimmunol.175.2.1232
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CD93 Is Rapidly Shed from the Surface of Human Myeloid Cells and the Soluble Form Is Detected in Human Plasma
Suzanne S. Bohlson, Richard Silva, Maria I. Fonseca and Andrea J. Tenner

J Immunol July 15, 2005, 175 (2) 1239-1247; DOI: https://doi.org/10.4049/jimmunol.175.2.1239
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Mechanisms Underlying Resistance of Pancreatic Islets from ALR/Lt Mice to Cytokine-Induced Destruction
Clayton E. Mathews, Wilma L. Suarez-Pinzon, Jeffrey J. Baust, Ken Strynadka, Edward H. Leiter and Alex Rabinovitch

J Immunol July 15, 2005, 175 (2) 1248-1256; DOI: https://doi.org/10.4049/jimmunol.175.2.1248
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A Non-Glycosaminoglycan-Binding Variant of CC Chemokine Ligand 7 (Monocyte Chemoattractant Protein-3) Antagonizes Chemokine-Mediated Inflammation
Simi Ali, Helen Robertson, Julie H. Wain, John D. Isaacs, Ghada Malik and John A. Kirby

J Immunol July 15, 2005, 175 (2) 1257-1266; DOI: https://doi.org/10.4049/jimmunol.175.2.1257
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P-Selectin Glycoprotein Ligand 1 Is Not Required for the Development of Experimental Autoimmune Encephalomyelitis in SJL and C57BL/6 Mice
Britta Engelhardt, Birgit Kempe, Stephanie Merfeld-Clauss, Melanie Laschinger, Bruce Furie, Martin K. Wild and Dietmar Vestweber

J Immunol July 15, 2005, 175 (2) 1267-1275; DOI: https://doi.org/10.4049/jimmunol.175.2.1267
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Mucosal B Cell Deficiency in IgA^−/− Mice Abrogates the Development of Allergic Lung Inflammation
Paul M. Arnaboldi, Melissa J. Behr and Dennis W. Metzger

J Immunol July 15, 2005, 175 (2) 1276-1285; DOI: https://doi.org/10.4049/jimmunol.175.2.1276

CLINICAL IMMUNOLOGY

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Hom s 4, an IgE-Reactive Autoantigen Belonging to a New Subfamily of Calcium-Binding Proteins, Can Induce Th Cell Type 1-Mediated Autoreactivity
Karl J. Aichberger, Irene Mittermann, Renate Reininger, Susanne Seiberler, Ines Swoboda, Susanne Spitzauer, Tamara Kopp, Georg Stingl, Wolfgang R. Sperr, Peter Valent, Andreas Repa, Barbara Bohle, Dietrich Kraft and Rudolf Valenta

J Immunol July 15, 2005, 175 (2) 1286-1294; DOI: https://doi.org/10.4049/jimmunol.175.2.1286
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Contribution of the Lymphotoxin β Receptor to Liver Regeneration
Robert A. Anders, Sumit K. Subudhi, Jing Wang, Klaus Pfeffer and Yang-Xin Fu

J Immunol July 15, 2005, 175 (2) 1295-1300; DOI: https://doi.org/10.4049/jimmunol.175.2.1295
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Targeting Positive Regulatory Domain I-Binding Factor 1 and X Box-Binding Protein 1 Transcription Factors by Multiple Myeloma-Reactive CTL
Carina Lotz, Sarah Abdel Mutallib, Nicole Oehlrich, Ulrike Liewer, Edite Antunes Ferreira, Marion Moos, Michael Hundemer, Sandra Schneider, Susanne Strand, Christoph Huber, Hartmut Goldschmidt and Matthias Theobald

J Immunol July 15, 2005, 175 (2) 1301-1309; DOI: https://doi.org/10.4049/jimmunol.175.2.1301
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IL-1β Induces IL-6 Expression in Human Orbital Fibroblasts: Identification of an Anatomic-Site Specific Phenotypic Attribute Relevant to Thyroid-Associated Ophthalmopathy
Beiling Chen, Shanli Tsui and Terry J. Smith

J Immunol July 15, 2005, 175 (2) 1310-1319; DOI: https://doi.org/10.4049/jimmunol.175.2.1310
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Host-Residual Invariant NK T Cells Attenuate Graft-versus-Host Immunity
Kyoko Haraguchi, Tsuyoshi Takahashi, Akihiko Matsumoto, Takashi Asai, Yoshinobu Kanda, Mineo Kurokawa, Seishi Ogawa, Hideaki Oda, Masaru Taniguchi, Hisamaru Hirai and Shigeru Chiba

J Immunol July 15, 2005, 175 (2) 1320-1328; DOI: https://doi.org/10.4049/jimmunol.175.2.1320
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Genotype-Proteotype Linkage in the Wiskott-Aldrich Syndrome
Maxim I. Lutskiy, Fred S. Rosen and Eileen Remold-O’Donnell

J Immunol July 15, 2005, 175 (2) 1329-1336; DOI: https://doi.org/10.4049/jimmunol.175.2.1329
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Genetic Dissection of Systemic Lupus Erythematosus Pathogenesis: Partial Functional Complementation between Sle1 and Sle3/5 Demonstrates Requirement for Intracellular Coexpression for Full Phenotypic Expression of Lupus
Masatoshi Wakui, Laurence Morel, Edward J. Butfiloski, Chunsun Kim and Eric S. Sobel

J Immunol July 15, 2005, 175 (2) 1337-1345; DOI: https://doi.org/10.4049/jimmunol.175.2.1337

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BRIEF REVIEW

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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