The Journal of Immunology: 174 (8)

April 15, 2005; Volume 174,Issue 8

IN THIS ISSUE

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IN THIS ISSUE

J Immunol April 15, 2005, 174 (8) 4449-4450; DOI: https://doi.org/10.4049/jimmunol.174.8.4449

LETTERS TO THE EDITOR

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Increased IgE but Reduced Th2-Type Inflammation in Vitamin D Receptor-Deficient Mice
Daniele D’Ambrosio

J Immunol April 15, 2005, 174 (8) 4451; DOI: https://doi.org/10.4049/jimmunol.174.8.4451

BRIEF REVIEWS

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TLR Signaling in the Gut in Health and Disease
Maria T. Abreu, Masayuki Fukata and Moshe Arditi

J Immunol April 15, 2005, 174 (8) 4453-4460; DOI: https://doi.org/10.4049/jimmunol.174.8.4453

CUTTING EDGE

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Cutting Edge: Death of a Dogma or Enforcing the Artificial: Monomeric IgE Binding May Initiate Mast Cell Response by Inducing Its Receptor Aggregation
Reinhard Schweitzer-Stenner and Israel Pecht

J Immunol April 15, 2005, 174 (8) 4461-4464; DOI: https://doi.org/10.4049/jimmunol.174.8.4461
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Cutting Edge: Type I IFNs Provide a Third Signal to CD8 T Cells to Stimulate Clonal Expansion and Differentiation
Julie M. Curtsinger, Javier O. Valenzuela, Pujya Agarwal, Debra Lins and Matthew F. Mescher

J Immunol April 15, 2005, 174 (8) 4465-4469; DOI: https://doi.org/10.4049/jimmunol.174.8.4465
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Cutting Edge: Fas Ligand (CD178) Cytoplasmic Tail Is a Positive Regulator of Fas Ligand-Mediated Cytotoxicity
Satoshi Jodo, Vyankatesh J. Pidiyar, Sheng Xiao, Akira Furusaki, Rahul Sharma, Takao Koike and Shyr-Te Ju

J Immunol April 15, 2005, 174 (8) 4470-4474; DOI: https://doi.org/10.4049/jimmunol.174.8.4470
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Cutting Edge: Itk Is Not Essential for CD28 Signaling in Naive T Cells
Cheng-Rui Li and Leslie J. Berg

J Immunol April 15, 2005, 174 (8) 4475-4479; DOI: https://doi.org/10.4049/jimmunol.174.8.4475
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Cutting Edge: NKG2D Is a Costimulatory Receptor for Human Naive CD8⁺ T Cells
Kerima Maasho, Jessica Opoku-Anane, Alina I. Marusina, John E. Coligan and Francisco Borrego

J Immunol April 15, 2005, 174 (8) 4480-4484; DOI: https://doi.org/10.4049/jimmunol.174.8.4480

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Generation of High-Affinity Antibody against T Cell-Dependent Antigen in the Ganp Gene-Transgenic Mouse
Nobuo Sakaguchi, Tetsuya Kimura, Shuzo Matsushita, Satoru Fujimura, Junji Shibata, Masatake Araki, Tamami Sakamoto, Chiemi Minoda and Kazuhiko Kuwahara

J Immunol April 15, 2005, 174 (8) 4485-4494; DOI: https://doi.org/10.4049/jimmunol.174.8.4485
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Regulation of Highly Cytokinergic IgE-Induced Mast Cell Adhesion by Src, Syk, Tec, and Protein Kinase C Family Kinases
Jiro Kitaura, Koji Eto, Tatsuya Kinoshita, Yuko Kawakami, Michael Leitges, Clifford A. Lowell and Toshiaki Kawakami

J Immunol April 15, 2005, 174 (8) 4495-4504; DOI: https://doi.org/10.4049/jimmunol.174.8.4495
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Antinuclear Antigen B Cells That Down-Regulate Surface B Cell Receptor during Development to Mature, Follicular Phenotype Do Not Display Features of Anergy In Vitro
Xiaohe Liu and Tim Manser

J Immunol April 15, 2005, 174 (8) 4505-4515; DOI: https://doi.org/10.4049/jimmunol.174.8.4505
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Active Tolerance Induction and Prevention of Autoimmune Diabetes by Immunogene Therapy Using Recombinant Adenoassociated Virus Expressing Glutamic Acid Decarboxylase 65 Peptide GAD_500–585
Gencheng Han, Yan Li, Jianan Wang, Renxi Wang, Guojiang Chen, Lun Song, Ruonan Xu, Ming Yu, Xiaobing Wu, Jiahua Qian and Beifen Shen

J Immunol April 15, 2005, 174 (8) 4516-4524; DOI: https://doi.org/10.4049/jimmunol.174.8.4516
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Treatment with Nonmitogenic Anti-CD3 Monoclonal Antibody Induces CD4⁺ T Cell Unresponsiveness and Functional Reversal of Established Experimental Autoimmune Encephalomyelitis
Adam P. Kohm, Julie S. Williams, Allison L. Bickford, Jeffrey S. McMahon, Lucienne Chatenoud, Jean-François Bach, Jeffrey A. Bluestone and Stephen D. Miller

J Immunol April 15, 2005, 174 (8) 4525-4534; DOI: https://doi.org/10.4049/jimmunol.174.8.4525
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Expression Profiling of Murine Double-Negative Regulatory T Cells Suggest Mechanisms for Prolonged Cardiac Allograft Survival
Boris P.-L. Lee, Elaine Mansfield, Szu-Chuan Hsieh, Tina Hernandez-Boussard, Wenhao Chen, Christopher W. Thomson, Megan S. Ford, Steven E. Bosinger, Sandy Der, Zhu-xu Zhang, Meixia Zhang, David J. Kelvin, Minnie M. Sarwal and Li Zhang

J Immunol April 15, 2005, 174 (8) 4535-4544; DOI: https://doi.org/10.4049/jimmunol.174.8.4535
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A Sexual Dimorphism in Intrathymic Sialylation Survey Is Revealed by the trans-Sialidase from Trypanosoma cruzi
Juan Mucci, Esteban Mocetti, María Susana Leguizamón and Oscar Campetella

J Immunol April 15, 2005, 174 (8) 4545-4550; DOI: https://doi.org/10.4049/jimmunol.174.8.4545
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Role for Glycogen Synthase Kinase-3 in NK Cell Cytotoxicity and X-Linked Lymphoproliferative Disease
Ala Aoukaty and Rusung Tan

J Immunol April 15, 2005, 174 (8) 4551-4558; DOI: https://doi.org/10.4049/jimmunol.174.8.4551
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Rapid Functional Exhaustion and Deletion of CTL following Immunization with Recombinant Adenovirus
Philippe Krebs, Elke Scandella, Bernhard Odermatt and Burkhard Ludewig

J Immunol April 15, 2005, 174 (8) 4559-4566; DOI: https://doi.org/10.4049/jimmunol.174.8.4559
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Altered Migration, Recruitment, and Somatic Hypermutation in the Early Response of Marginal Zone B Cells to T Cell-Dependent Antigen
Tri Giang Phan, Sandra Gardam, Antony Basten and Robert Brink

J Immunol April 15, 2005, 174 (8) 4567-4578; DOI: https://doi.org/10.4049/jimmunol.174.8.4567
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Suppressive Oligodeoxynucleotides Protect Mice from Lethal Endotoxic Shock
Hidekazu Shirota, Ihsan Gursel, Mayda Gursel and Dennis M. Klinman

J Immunol April 15, 2005, 174 (8) 4579-4583; DOI: https://doi.org/10.4049/jimmunol.174.8.4579
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Microtubule Disruption Suppresses Allergic Response through the Inhibition of Calcium Influx in the Mast Cell Degranulation Pathway
Tatsuya Oka, Masatoshi Hori and Hiroshi Ozaki

J Immunol April 15, 2005, 174 (8) 4584-4589; DOI: https://doi.org/10.4049/jimmunol.174.8.4584
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NK Cells Inhibit T Cell Proliferation via p21-Mediated Cell Cycle Arrest
Prachi P. Trivedi, Paul C. Roberts, Norbert A. Wolf and Robert H. Swanborg

J Immunol April 15, 2005, 174 (8) 4590-4597; DOI: https://doi.org/10.4049/jimmunol.174.8.4590
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Does the Frequency and Avidity Spectrum of the Neuroantigen-Specific T Cells in the Blood Mirror the Autoimmune Process in the Central Nervous System of Mice Undergoing Experimental Allergic Encephalomyelitis?
Harald H. Hofstetter, Oleg S. Targoni, Alexey Y. Karulin, Thomas G. Forsthuber, Magdalena Tary-Lehmann and Paul V. Lehmann

J Immunol April 15, 2005, 174 (8) 4598-4605; DOI: https://doi.org/10.4049/jimmunol.174.8.4598
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γδ T Cell Homeostasis Is Controlled by IL-7 and IL-15 Together with Subset-Specific Factors
Roberto Baccala, Deborah Witherden, Rosana Gonzalez-Quintial, Wolfgang Dummer, Charles D. Surh, Wendy L. Havran and Argyrios N. Theofilopoulos

J Immunol April 15, 2005, 174 (8) 4606-4612; DOI: https://doi.org/10.4049/jimmunol.174.8.4606
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Rac2 Regulates Neutrophil Chemotaxis, Superoxide Production, and Myeloid Colony Formation through Multiple Distinct Effector Pathways
Dirk Carstanjen, Akira Yamauchi, Annemart Koornneef, Heesuk Zang, Marie-Dominique Filippi, Chad Harris, Jason Towe, Simon Atkinson, Yi Zheng, Mary C. Dinauer and David A. Williams

J Immunol April 15, 2005, 174 (8) 4613-4620; DOI: https://doi.org/10.4049/jimmunol.174.8.4613
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Inhibitory NK Receptor Ly49Q Is Expressed on Subsets of Dendritic Cells in a Cellular Maturation- and Cytokine Stimulation-Dependent Manner
Noriko Toyama-Sorimachi, Yoshiki Omatsu, Atsuko Onoda, Yusuke Tsujimura, Tomonori Iyoda, Akiko Kikuchi-Maki, Hiroyuki Sorimachi, Taeko Dohi, Shinsuke Taki, Kayo Inaba and Hajime Karasuyama

J Immunol April 15, 2005, 174 (8) 4621-4629; DOI: https://doi.org/10.4049/jimmunol.174.8.4621
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Suppressive Effect of IL-4 on IL-13-Induced Genes in Mouse Lung
Fred D. Finkelman, Mingyan Yang, Charles Perkins, Kathleen Schleifer, Alyssa Sproles, JoAnna Santeliz, Jonathan A. Bernstein, Marc E. Rothenberg, Suzanne C. Morris and Marsha Wills-Karp

J Immunol April 15, 2005, 174 (8) 4630-4638; DOI: https://doi.org/10.4049/jimmunol.174.8.4630
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Signals from CD28 Induce Stable Epigenetic Modification of the IL-2 Promoter
Rajan M. Thomas, Ling Gao and Andrew D. Wells

J Immunol April 15, 2005, 174 (8) 4639-4646; DOI: https://doi.org/10.4049/jimmunol.174.8.4639
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Translation from Cryptic Reading Frames of DNA Vaccines Generates an Extended Repertoire of Immunogenic, MHC Class I-Restricted Epitopes
Reinhold Schirmbeck, Petra Riedl, Nicolas Fissolo, Francois A. Lemonnier, Antonio Bertoletti and Jörg Reimann

J Immunol April 15, 2005, 174 (8) 4647-4656; DOI: https://doi.org/10.4049/jimmunol.174.8.4647
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Fetal Expression of Fas Ligand Is Necessary and Sufficient for Induction of CD8 T Cell Tolerance to the Fetal Antigen H-Y during Pregnancy
Melanie S. Vacchio and Richard J. Hodes

J Immunol April 15, 2005, 174 (8) 4657-4661; DOI: https://doi.org/10.4049/jimmunol.174.8.4657
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T Cell-Mediated Delay of Spontaneous Mammary Tumor Onset: Increased Efficacy with In Vivo versus In Vitro Activation
Leigh A. O’Mara, Lyse A. Norian, Darren Kreamalmeyer, J. Michael White and Paul M. Allen

J Immunol April 15, 2005, 174 (8) 4662-4669; DOI: https://doi.org/10.4049/jimmunol.174.8.4662
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Glucose Availability Regulates IFN-γ Production and p70S6 Kinase Activation in CD8⁺ Effector T Cells
Candace M. Cham and Thomas F. Gajewski

J Immunol April 15, 2005, 174 (8) 4670-4677; DOI: https://doi.org/10.4049/jimmunol.174.8.4670
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γδ T Cells Regulate the Extent and Duration of Inflammation in the Central Nervous System by a Fas Ligand-Dependent Mechanism
Eugene D. Ponomarev and Bonnie N. Dittel

J Immunol April 15, 2005, 174 (8) 4678-4687; DOI: https://doi.org/10.4049/jimmunol.174.8.4678
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IL-12-Independent LIGHT Signaling Enhances MHC Class II Disparate CD4⁺ T Cell Alloproliferation, IFN-γ Responses, and Intestinal Graft-versus-Host Disease
Geri R. Brown, Edward L. Lee, Jihad El-Hayek, Katherine Kintner and Cheryl Luck

J Immunol April 15, 2005, 174 (8) 4688-4695; DOI: https://doi.org/10.4049/jimmunol.174.8.4688
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Distinct Roles of Dendritic Cells and B Cells in Va14Ja18 Natural T Cell Activation In Vivo
Jelena S. Bezbradica, Aleksandar K. Stanic, Naoto Matsuki, Helene Bour-Jordan, Jeffrey A. Bluestone, James W. Thomas, Derya Unutmaz, Luc Van Kaer and Sebastian Joyce

J Immunol April 15, 2005, 174 (8) 4696-4705; DOI: https://doi.org/10.4049/jimmunol.174.8.4696
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Macrophage Colony-Stimulating Factor Drives Cord Blood Monocyte Differentiation into IL-10^highIL-12^absent Dendritic Cells with Tolerogenic Potential
Geling Li, Young-June Kim and Hal E. Broxmeyer

J Immunol April 15, 2005, 174 (8) 4706-4717; DOI: https://doi.org/10.4049/jimmunol.174.8.4706
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T Regulatory-1 Cells Induce IgG4 Production by B Cells: Role of IL-10
Judith S. Satoguina, Esther Weyand, John Larbi and Achim Hoerauf

J Immunol April 15, 2005, 174 (8) 4718-4726; DOI: https://doi.org/10.4049/jimmunol.174.8.4718
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Tumor Vaccine Based on Cell Surface Expression of DcR3/TR6
Guixiu Shi, Jianning Mao, Guang Yu, Jun Zhang and Jiangping Wu

J Immunol April 15, 2005, 174 (8) 4727-4735; DOI: https://doi.org/10.4049/jimmunol.174.8.4727
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Pattern of Kvβ Subunit Expression in Macrophages Depends upon Proliferation and the Mode of Activation
Rubén Vicente, Artur Escalada, Concepció Soler, Maribel Grande, Antonio Celada, Michael M. Tamkun, Carles Solsona and Antonio Felipe

J Immunol April 15, 2005, 174 (8) 4736-4744; DOI: https://doi.org/10.4049/jimmunol.174.8.4736
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A Role for SATB1, a Nuclear Matrix Association Region-Binding Protein, in the Development of CD8SP Thymocytes and Peripheral T Lymphocytes
Hui Nie, Shanna D. Maika, Philip W. Tucker and Paul D. Gottlieb

J Immunol April 15, 2005, 174 (8) 4745-4752; DOI: https://doi.org/10.4049/jimmunol.174.8.4745
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Dysfunction of Simian Immunodeficiency Virus/Simian Human Immunodeficiency Virus-Induced IL-2 Expression by Central Memory CD4⁺ T Lymphocytes
Yue Sun, Jörn E. Schmitz, Paula M. Acierno, Sampa Santra, Ramu A. Subbramanian, Dan H. Barouch, Darci A. Gorgone, Michelle A. Lifton, Kristin R. Beaudry, Kelledy Manson, Valerie Philippon, Ling Xu, Holden T. Maecker, John R. Mascola, Dennis Panicali, Gary J. Nabel and Norman L. Letvin

J Immunol April 15, 2005, 174 (8) 4753-4760; DOI: https://doi.org/10.4049/jimmunol.174.8.4753
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IL-6 Increases Primed Cell Expansion and Survival
Irina Rochman, William E. Paul and S. Z. Ben-Sasson

J Immunol April 15, 2005, 174 (8) 4761-4767; DOI: https://doi.org/10.4049/jimmunol.174.8.4761

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Recognition of Human Cytomegalovirus by Human Primary Immunoglobulins Identifies an Innate Foundation to an Adaptive Immune Response
Gary R. McLean, Ole A. Olsen, Ian N. Watt, P. Rathanaswami, Kevin B. Leslie, John S. Babcook and John W. Schrader

J Immunol April 15, 2005, 174 (8) 4768-4778; DOI: https://doi.org/10.4049/jimmunol.174.8.4768
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HIV Type 1 Can Act as an APC upon Acquisition from the Host Cell of Peptide-Loaded HLA-DR and CD86 Molecules
Jocelyn Roy, Geneviève Martin, Jean-François Giguère, Dave Bélanger, Myriam Pétrin and Michel J. Tremblay

J Immunol April 15, 2005, 174 (8) 4779-4788; DOI: https://doi.org/10.4049/jimmunol.174.8.4779
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Functional Requirements for Signaling through the Stimulatory and Inhibitory Mouse NKR-P1 (CD161) NK Cell Receptors
Belma Ljutic, James R. Carlyle, Dominik Filipp, Rinako Nakagawa, Michael Julius and Juan Carlos Zúñiga-Pflücker

J Immunol April 15, 2005, 174 (8) 4789-4796; DOI: https://doi.org/10.4049/jimmunol.174.8.4789
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B Cell Hyperresponsiveness and Expansion of Mature Follicular B Cells but Not of Marginal Zone B Cells in NFATc2/c3 Double-Deficient Mice
Devapriya Nandini Samanta, Alois Palmetshofer, Dragan Marinkovic, Thomas Wirth, Edgar Serfling and Lars Nitschke

J Immunol April 15, 2005, 174 (8) 4797-4802; DOI: https://doi.org/10.4049/jimmunol.174.8.4797
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Exocytosis of CTLA-4 Is Dependent on Phospholipase D and ADP Ribosylation Factor-1 and Stimulated during Activation of Regulatory T Cells
Karen I. Mead, Yong Zheng, Claire N. Manzotti, Laura C. A. Perry, Michael K. P. Liu, Fiona Burke, Dale J. Powner, Michael J. O. Wakelam and David M. Sansom

J Immunol April 15, 2005, 174 (8) 4803-4811; DOI: https://doi.org/10.4049/jimmunol.174.8.4803
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Increased Immunogenicity of an Anchor-Modified Tumor-Associated Antigen Is Due to the Enhanced Stability of the Peptide/MHC Complex: Implications for Vaccine Design
Oleg Y. Borbulevych, Tiffany K. Baxter, Zhiya Yu, Nicholas P. Restifo and Brian M. Baker

J Immunol April 15, 2005, 174 (8) 4812-4820; DOI: https://doi.org/10.4049/jimmunol.174.8.4812

IMMUNOGENETICS

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The Enlarged Population of Marginal Zone/CD1d^high B Lymphocytes in Nonobese Diabetic Mice Maps to Diabetes Susceptibility Region Idd11
Julia Rolf, Vinicius Motta, Nadia Duarte, Marie Lundholm, Emma Berntman, Marie-Louise Bergman, Lydia Sorokin, Susanna L. Cardell and Dan Holmberg

J Immunol April 15, 2005, 174 (8) 4821-4827; DOI: https://doi.org/10.4049/jimmunol.174.8.4821

HOST DEFENSE

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Intraepithelial Cell Neutralization of HIV-1 Replication by IgA
Yung T. Huang, Alison Wright, Xing Gao, Lesya Kulick, Huimin Yan and Michael E. Lamm

J Immunol April 15, 2005, 174 (8) 4828-4835; DOI: https://doi.org/10.4049/jimmunol.174.8.4828
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Polymorphonuclear Neutrophils Improve Replication of Chlamydia pneumoniae In Vivo upon MyD88-Dependent Attraction
Nuria Rodriguez, Falko Fend, Luise Jennen, Matthias Schiemann, Nina Wantia, Clarissa U. Prazeres da Costa, Susanne Dürr, Ulrich Heinzmann, Hermann Wagner and Thomas Miethke

J Immunol April 15, 2005, 174 (8) 4836-4844; DOI: https://doi.org/10.4049/jimmunol.174.8.4836
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Microbial Antigen Triggers Rapid Mobilization of TNF-α to the Surface of Mouse Neutrophils Transforming Them into Inducers of High-Level Dendritic Cell TNF-α Production
Soumaya Bennouna and Eric Y. Denkers

J Immunol April 15, 2005, 174 (8) 4845-4851; DOI: https://doi.org/10.4049/jimmunol.174.8.4845
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Transmembrane TNF Is Sufficient to Initiate Cell Migration and Granuloma Formation and Provide Acute, but Not Long-Term, Control of Mycobacterium tuberculosis Infection
Bernadette M. Saunders, Stephen Tran, Sigrid Ruuls, Jonathon D. Sedgwick, Helen Briscoe and Warwick J. Britton

J Immunol April 15, 2005, 174 (8) 4852-4859; DOI: https://doi.org/10.4049/jimmunol.174.8.4852
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Molecular Basis for the Potency of IL-10-Deficient Dendritic Cells as a Highly Efficient APC System for Activating Th1 Response
Qing He, Terri T. Moore, Francis O. Eko, Deborah Lyn, Godwin A. Ananaba, Amy Martin, Shailesh Singh, Lillard James, Jonathan Stiles, Carolyn M. Black and Joseph U. Igietseme

J Immunol April 15, 2005, 174 (8) 4860-4869; DOI: https://doi.org/10.4049/jimmunol.174.8.4860
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Differential Regulation of β-Defensin Expression in Human Skin by Microbial Stimuli
Ole E. Sørensen, Dharma R. Thapa, Adam Rosenthal, Lide Liu, Alice A. Roberts and Tomas Ganz

J Immunol April 15, 2005, 174 (8) 4870-4879; DOI: https://doi.org/10.4049/jimmunol.174.8.4870
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STAT1 Signaling Regulates Tumor-Associated Macrophage-Mediated T Cell Deletion
Sergei Kusmartsev and Dmitry I. Gabrilovich

J Immunol April 15, 2005, 174 (8) 4880-4891; DOI: https://doi.org/10.4049/jimmunol.174.8.4880
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Roles for CXC Chemokine Ligands 10 and 11 in Recruiting CD4⁺ T Cells to HIV-1-Infected Monocyte-Derived Macrophages, Dendritic Cells, and Lymph Nodes
John F. Foley, Cheng-Rong Yu, Rikki Solow, Maureen Yacobucci, Keith W. C. Peden and Joshua M. Farber

J Immunol April 15, 2005, 174 (8) 4892-4900; DOI: https://doi.org/10.4049/jimmunol.174.8.4892
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Cathelicidin Mediates Innate Intestinal Defense against Colonization with Epithelial Adherent Bacterial Pathogens
Mitsutoshi Iimura, Richard L. Gallo, Koji Hase, Yukiko Miyamoto, Lars Eckmann and Martin F. Kagnoff

J Immunol April 15, 2005, 174 (8) 4901-4907; DOI: https://doi.org/10.4049/jimmunol.174.8.4901
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Receptor-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Spike Protein Contains Multiple Conformation-Dependent Epitopes that Induce Highly Potent Neutralizing Antibodies
Yuxian He, Hong Lu, Pamela Siddiqui, Yusen Zhou and Shibo Jiang

J Immunol April 15, 2005, 174 (8) 4908-4915; DOI: https://doi.org/10.4049/jimmunol.174.8.4908
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Prevention of Relapse after Chemotherapy in a Chronic Intracellular Infection: Mechanisms in Experimental Visceral Leishmaniasis
Henry W. Murray

J Immunol April 15, 2005, 174 (8) 4916-4923; DOI: https://doi.org/10.4049/jimmunol.174.8.4916
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Removal of Regulatory T Cell Activity Reverses Hyporesponsiveness and Leads to Filarial Parasite Clearance In Vivo
Matthew D. Taylor, Laetitia LeGoff, Anjanette Harris, Eva Malone, Judith E. Allen and Rick M. Maizels

J Immunol April 15, 2005, 174 (8) 4924-4933; DOI: https://doi.org/10.4049/jimmunol.174.8.4924
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Anthrax Edema Toxin Cooperates with Lethal Toxin to Impair Cytokine Secretion during Infection of Dendritic Cells
Jean-Nicolas Tournier, Anne Quesnel-Hellmann, Jacques Mathieu, Cesare Montecucco, Wei-Jen Tang, Michèle Mock, Dominique R. Vidal and Pierre L. Goossens

J Immunol April 15, 2005, 174 (8) 4934-4941; DOI: https://doi.org/10.4049/jimmunol.174.8.4934
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Apoptosis Induced by the Toll-Like Receptor Adaptor TRIF Is Dependent on Its Receptor Interacting Protein Homotypic Interaction Motif
William J. Kaiser and Margaret K. Offermann

J Immunol April 15, 2005, 174 (8) 4942-4952; DOI: https://doi.org/10.4049/jimmunol.174.8.4942
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Surfactant Protein-D Regulates Soluble CD14 through Matrix Metalloproteinase-12
Albert P. Senft, Thomas R. Korfhagen, Jeffrey A. Whitsett, Steven D. Shapiro and Ann Marie LeVine

J Immunol April 15, 2005, 174 (8) 4953-4959; DOI: https://doi.org/10.4049/jimmunol.174.8.4953
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Activation-Induced Depletion of Protein Kinase Cα Provokes Desensitization of Monocytes/Macrophages in Sepsis
Andreas von Knethen, Anja Tautenhahn, Hartmut Link, Dirk Lindemann and Bernhard Brüne

J Immunol April 15, 2005, 174 (8) 4960-4965; DOI: https://doi.org/10.4049/jimmunol.174.8.4960
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Anthrax Lethal Toxin Blocks MAPK Kinase-Dependent IL-2 Production in CD4⁺ T Cells
Hui Fang, Ruth Cordoba-Rodriguez, Carla S. R. Lankford and David M. Frucht

J Immunol April 15, 2005, 174 (8) 4966-4971; DOI: https://doi.org/10.4049/jimmunol.174.8.4966
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Early Establishment of γ-Herpesvirus Latency: Implications for Immune Control
Emilio Flaño, Qingmei Jia, John Moore, David L. Woodland, Ren Sun and Marcia A. Blackman

J Immunol April 15, 2005, 174 (8) 4972-4978; DOI: https://doi.org/10.4049/jimmunol.174.8.4972

INFLAMMATION

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Leukotriene B4 Receptor-1 Is Essential for Allergen-Mediated Recruitment of CD8⁺ T Cells and Airway Hyperresponsiveness
Nobuaki Miyahara, Katsuyuki Takeda, Satoko Miyahara, Christian Taube, Anthony Joetham, Toshiyuki Koya, Shigeki Matsubara, Azzeddine Dakhama, Andrew M. Tager, Andrew D. Luster and Erwin W. Gelfand

J Immunol April 15, 2005, 174 (8) 4979-4984; DOI: https://doi.org/10.4049/jimmunol.174.8.4979
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Dominant Role for TL1A/DR3 Pathway in IL-12 plus IL-18-Induced IFN-γ Production by Peripheral Blood and Mucosal CCR9⁺ T Lymphocytes
Konstantinos A. Papadakis, Daocheng Zhu, John L. Prehn, Carol Landers, Armine Avanesyan, Gina Lafkas and Stephan R. Targan

J Immunol April 15, 2005, 174 (8) 4985-4990; DOI: https://doi.org/10.4049/jimmunol.174.8.4985
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IL-1β-Mediated Innate Immunity Is Amplified in the db/db Mouse Model of Type 2 Diabetes
Jason C. O’Connor, Ansuman Satpathy, Matthew E. Hartman, Emily M. Horvath, Keith W. Kelley, Robert Dantzer, Rodney W. Johnson and Gregory G. Freund

J Immunol April 15, 2005, 174 (8) 4991-4997; DOI: https://doi.org/10.4049/jimmunol.174.8.4991
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Composition of the Lectin Pathway of Complement in Gallus gallus: Absence of Mannan-Binding Lectin-Associated Serine Protease-1 in Birds
Nicholas J. Lynch, Saeed-ul-Hassan Khan, Cordula M. Stover, Sara M. Sandrini, Denise Marston, Julia S. Presanis and Wilhelm J. Schwaeble

J Immunol April 15, 2005, 174 (8) 4998-5006; DOI: https://doi.org/10.4049/jimmunol.174.8.4998
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In Vivo Activity of Released Cell Wall Lipids of Mycobacterium bovis Bacillus Calmette-Guérin Is Due Principally to Trehalose Mycolates
Rachel E. Geisel, Kaori Sakamoto, David G. Russell and Elizabeth R. Rhoades

J Immunol April 15, 2005, 174 (8) 5007-5015; DOI: https://doi.org/10.4049/jimmunol.174.8.5007
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TLR2 Signaling in Chondrocytes Drives Calcium Pyrophosphate Dihydrate and Monosodium Urate Crystal-Induced Nitric Oxide Generation
Ru Liu-Bryan, Kenneth Pritzker, Gary S. Firestein and Robert Terkeltaub

J Immunol April 15, 2005, 174 (8) 5016-5023; DOI: https://doi.org/10.4049/jimmunol.174.8.5016
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Allergen Drives Class Switching to IgE in the Nasal Mucosa in Allergic Rhinitis
Pooja Takhar, Lyn Smurthwaite, Heather A. Coker, David J. Fear, Graham K. Banfield, Victoria A. Carr, Stephen R. Durham and Hannah J. Gould

J Immunol April 15, 2005, 174 (8) 5024-5032; DOI: https://doi.org/10.4049/jimmunol.174.8.5024
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Cyclooxygenase 2 Plays a Pivotal Role in the Resolution of Acute Lung Injury
Koichi Fukunaga, Payal Kohli, Caroline Bonnans, Laura E. Fredenburgh and Bruce D. Levy

J Immunol April 15, 2005, 174 (8) 5033-5039; DOI: https://doi.org/10.4049/jimmunol.174.8.5033
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A_2A Adenosine Receptors on Bone Marrow-Derived Cells Protect Liver from Ischemia-Reperfusion Injury
Yuan-Ji Day, Yuesheng Li, Jayson M. Rieger, Susan I. Ramos, Mark D. Okusa and Joel Linden

J Immunol April 15, 2005, 174 (8) 5040-5046; DOI: https://doi.org/10.4049/jimmunol.174.8.5040
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ERK1/2 Regulates Epidermal Chemokine Expression and Skin Inflammation
Saveria Pastore, Francesca Mascia, Feliciana Mariotti, Cristina Dattilo, Valentina Mariani and Giampiero Girolomoni

J Immunol April 15, 2005, 174 (8) 5047-5056; DOI: https://doi.org/10.4049/jimmunol.174.8.5047

CLINICAL IMMUNOLOGY

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Fibrin Deimination in Synovial Tissue Is Not Specific for Rheumatoid Arthritis but Commonly Occurs during Synovitides
Sabine Chapuy-Regaud, Mireille Sebbag, Dominique Baeten, Cyril Clavel, Céline Foulquier, Filip De Keyser and Guy Serre

J Immunol April 15, 2005, 174 (8) 5057-5064; DOI: https://doi.org/10.4049/jimmunol.174.8.5057
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Autoimmune Alterations Induced by the New Zealand Black Lbw2 Locus in BWF1 Mice
Maria K. Haraldsson, Nathanial G. dela Paz, Jason G. Kuan, Gary S. Gilkeson, Argyrios N. Theofilopoulos and Dwight H. Kono

J Immunol April 15, 2005, 174 (8) 5065-5073; DOI: https://doi.org/10.4049/jimmunol.174.8.5065
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Bone Marrow Clonogenic Capability, Cytokine Production, and Thymic Output in Patients with Common Variable Immunodeficiency
Antonella Isgrò, Marco Marziali, Ivano Mezzaroma, Giuseppe Luzi, Anna Maria Mazzone, Vanessa Guazzi, Grazia Andolfi, Barbara Cassani, Alessandro Aiuti and Fernando Aiuti

J Immunol April 15, 2005, 174 (8) 5074-5081; DOI: https://doi.org/10.4049/jimmunol.174.8.5074
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CCL1-CCR8 Interactions: An Axis Mediating the Recruitment of T Cells and Langerhans-Type Dendritic Cells to Sites of Atopic Skin Inflammation
Michael Gombert, Marie-Caroline Dieu-Nosjean, Franziska Winterberg, Erich Bünemann, Robert C. Kubitza, Ludivine Da Cunha, Anna Haahtela, Sari Lehtimäki, Anja Müller, Juliane Rieker, Stephan Meller, Andor Pivarcsi, Andrea Koreck, Wolf-Herman Fridman, Hans-Walter Zentgraf, Hermann Pavenstädt, Ali Amara, Christophe Caux, Lajos Kemeny, Harri Alenius, Antti Lauerma, Thomas Ruzicka, Albert Zlotnik and Bernhard Homey

J Immunol April 15, 2005, 174 (8) 5082-5091; DOI: https://doi.org/10.4049/jimmunol.174.8.5082
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CD4⁺ T Cell Responses to SSX-4 in Melanoma Patients
Maha Ayyoub, Andrea Merlo, Charles S. Hesdorffer, Donata Rimoldi, Daniel Speiser, Jean-Charles Cerottini, Yao-Tseng Chen, Lloyd J. Old, Stefan Stevanovic and Danila Valmori

J Immunol April 15, 2005, 174 (8) 5092-5099; DOI: https://doi.org/10.4049/jimmunol.174.8.5092
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Naive CD4⁺ T Cells from Lupus-Prone Fas-Intact MRL Mice Display TCR-Mediated Hyperproliferation Due to Intrinsic Threshold Defects in Activation
Christina E. Zielinski, Simon N. Jacob, Farida Bouzahzah, Barbara E. Ehrlich and Joe Craft

J Immunol April 15, 2005, 174 (8) 5100-5109; DOI: https://doi.org/10.4049/jimmunol.174.8.5100
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Accelerated Lymphocyte Death in Sepsis Occurs by both the Death Receptor and Mitochondrial Pathways
Richard S. Hotchkiss, Stephen B. Osmon, Katherine C. Chang, Tracey H. Wagner, Craig M. Coopersmith and Irene E. Karl

J Immunol April 15, 2005, 174 (8) 5110-5118; DOI: https://doi.org/10.4049/jimmunol.174.8.5110
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Coinfection with Schistosoma mansoni Is Associated with Decreased HIV-Specific Cytolysis and Increased IL-10 Production
Michael D. McElroy, Mohamed Elrefaei, Norman Jones, Francis Ssali, Peter Mugyenyi, Banson Barugahare and Huyen Cao

J Immunol April 15, 2005, 174 (8) 5119-5123; DOI: https://doi.org/10.4049/jimmunol.174.8.5119
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Neutrophils That Infiltrate the Central Nervous System Regulate T Cell Responses
Simone P. Zehntner, Cristina Brickman, Lyne Bourbonnière, Leah Remington, Maria Caruso and Trevor Owens

J Immunol April 15, 2005, 174 (8) 5124-5131; DOI: https://doi.org/10.4049/jimmunol.174.8.5124

CORRECTIONS

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The Expression and Functional Involvement of Laminin-Like Molecules in Non-MHC Restricted Cytotoxicity by Human Leu-19⁺/CD3⁻ Natural Killer Lymphocytes
Roderich E. Schwarz and John C. Hiserodt

J Immunol April 15, 2005, 174 (8) 5132; DOI: https://doi.org/10.4049/jimmunol.174.8.5132
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Differential Expression of the Inhibitory IgG Fc Receptor FcγRIIB on Germinal Center Cells: Implications for Selection of High-Affinity B Cells
Sambasiva P. Rao, Kalpit A. Vora and Tim Manser

J Immunol April 15, 2005, 174 (8) 5133; DOI: https://doi.org/10.4049/jimmunol.174.8.5133
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IL-2 Overcomes the Unresponsiveness but Fails to Reverse the Regulatory Function of Antigen-Induced T Regulatory Cells
Per O. Anderson, Anette Sundstedt, Zihni Yazici, Sophie Minaee, Richard Woolf, Kirsty Nicolson, Nathaniel Whitley, Li Li, Suling Li, David C. Wraith and Ping Wang

J Immunol April 15, 2005, 174 (8) 5133; DOI: https://doi.org/10.4049/jimmunol.174.8.5133-a
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The Wiskott-Aldrich Syndrome Protein Regulates Nuclear Translocation of NFAT2 and NF-κB (RelA) Independently of Its Role in Filamentous Actin Polymerization and Actin Cytoskeletal Rearrangement
Winifred Huang, Hans D. Ochs, Bo Dupont and Yatin M. Vyas

J Immunol April 15, 2005, 174 (8) 5134; DOI: https://doi.org/10.4049/jimmunol.174.8.5134
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Activated Human B Lymphocytes Express Cyclooxygenase-2 and Cyclooxygenase Inhibitors Attenuate Ab Production
Elizabeth P. Ryan, Stephen J. Pollack, Thomas I. Murant, Steven H. Bernstein, Raymond E. Felgar and Richard P. Phipps

J Immunol April 15, 2005, 174 (8) 5134; DOI: https://doi.org/10.4049/jimmunol.174.8.5134-a
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In This Issue
J Immunol April 15, 2005, 174 (8) 5135; DOI: https://doi.org/10.4049/jimmunol.174.8.5135
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Alloreactive T Cell Responses and Acute Rejection of Single Class II MHC-Disparate Heart Allografts Are under Strict Regulation by CD4⁺CD25⁺ T Cells.
Soren Schenk, Danielle D. Kish, Chunshui He, Tarek El-Sawy, Eise Chiffoleau, Chuangqui Chen, Zihao Wu, Sigrid Sandner, Anton V. Gorbachev, Kiyotaka Fukamachi, Peter S. Heeger, Mohamed H. Sayegh, Laurence A. Turka and Robert L. Fairchild

J Immunol April 15, 2005, 174 (8) 5135; DOI: https://doi.org/10.4049/jimmunol.174.8.5135-a

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IN THIS ISSUE

LETTERS TO THE EDITOR

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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