The Journal of Immunology: 174 (6)

March 15, 2005; Volume 174,Issue 6

IN THIS ISSUE

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IN THIS ISSUE

J Immunol March 15, 2005, 174 (6) 3135-3136; DOI: https://doi.org/10.4049/jimmunol.174.6.3135

BRIEF REVIEWS

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Leptin in Immunology
Giuseppe Matarese, Stergios Moschos and Christos S. Mantzoros

J Immunol March 15, 2005, 174 (6) 3137-3142; DOI: https://doi.org/10.4049/jimmunol.174.6.3137

CUTTING EDGE

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Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients
Jan Andersson, Adriano Boasso, Jakob Nilsson, Rui Zhang, Norah J. Shire, Stefan Lindback, Gene M. Shearer and Claire A. Chougnet

J Immunol March 15, 2005, 174 (6) 3143-3147; DOI: https://doi.org/10.4049/jimmunol.174.6.3143
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Cutting Edge: IL-10-Independent STAT3 Activation by Toxoplasma gondii Mediates Suppression of IL-12 and TNF-α in Host Macrophages
Barbara A. Butcher, Leesun Kim, Athanasia D. Panopoulos, Stephanie S. Watowich, Peter J. Murray and Eric Y. Denkers

J Immunol March 15, 2005, 174 (6) 3148-3152; DOI: https://doi.org/10.4049/jimmunol.174.6.3148
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Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions
Brian Chung, Ala Aoukaty, Jan Dutz, Cox Terhorst and Rusung Tan

J Immunol March 15, 2005, 174 (6) 3153-3157; DOI: https://doi.org/10.4049/jimmunol.174.6.3153
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Cutting Edge: Recent Immune Status Determines the Source of Antigens That Drive Homeostatic T Cell Expansion
William C. Kieper, Amy Troy, J. Theodore Burghardt, Chris Ramsey, Joon Youb Lee, Han-Qing Jiang, Wolfgang Dummer, Hao Shen, John J. Cebra and Charles D. Surh

J Immunol March 15, 2005, 174 (6) 3158-3163; DOI: https://doi.org/10.4049/jimmunol.174.6.3158
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Cutting Edge: Stat5 Mediates the IL-7-Induced Accessibility of a Representative D-Distal V_H Gene
Michelle L. Stanton and Peter H. Brodeur

J Immunol March 15, 2005, 174 (6) 3164-3168; DOI: https://doi.org/10.4049/jimmunol.174.6.3164
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Cutting Edge: Novel Role of Lipoxygenases in the Inflammatory Response: Promotion of TNF mRNA Decay by 15-Hydroperoxyeicosatetraenoic Acid in a Monocytic Cell Line
Judith V. Ferrante and Antonio Ferrante

J Immunol March 15, 2005, 174 (6) 3169-3172; DOI: https://doi.org/10.4049/jimmunol.174.6.3169
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Cutting Edge: Spontaneously Ig-Secreting B-1 Cells Violate the Accepted Paradigm for Expression of Differentiation-Associated Transcription Factors
Joseph R. Tumang, Rubén Francés, Seung Geun Yeo and Thomas L. Rothstein

J Immunol March 15, 2005, 174 (6) 3173-3177; DOI: https://doi.org/10.4049/jimmunol.174.6.3173

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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The Mouse CD1d Cytoplasmic Tail Mediates CD1d Trafficking and Antigen Presentation by Adaptor Protein 3-Dependent and -Independent Mechanisms
Anna P. Lawton, Theodore I. Prigozy, Laurent Brossay, Bo Pei, Archana Khurana, Donald Martin, Tiancheng Zhu, Kira Späte, Megda Ozga, Stefan Höning, Oddmund Bakke and Mitchell Kronenberg

J Immunol March 15, 2005, 174 (6) 3179-3186; DOI: https://doi.org/10.4049/jimmunol.174.6.3179
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Rationally Engineered Therapeutic Proteins with Reduced Immunogenicity
Shabnam Tangri, Bianca R. Mothé, Julie Eisenbraun, John Sidney, Scott Southwood, Kristen Briggs, John Zinckgraf, Pamuk Bilsel, Mark Newman, Robert Chesnut, Cynthia LiCalsi and Alessandro Sette

J Immunol March 15, 2005, 174 (6) 3187-3196; DOI: https://doi.org/10.4049/jimmunol.174.6.3187
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CD4⁻ Plasmacytoid Dendritic Cells (pDCs) Migrate in Lymph Nodes by CpG Inoculation and Represent a Potent Functional Subset of pDCs
Guo-Xiang Yang, Zhe-Xiong Lian, Kentaro Kikuchi, Yong-Jun Liu, Aftab A. Ansari, Susumu Ikehara and M. Eric Gershwin

J Immunol March 15, 2005, 174 (6) 3197-3203; DOI: https://doi.org/10.4049/jimmunol.174.6.3197
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Clustering of T Cell Ligands on Artificial APC Membranes Influences T Cell Activation and Protein Kinase C θ Translocation to the T Cell Plasma Membrane
Francesca Giannoni, Joellen Barnett, Kun Bi, Rodrigo Samodal, Paola Lanza, Patrizia Marchese, Rosario Billetta, Randi Vita, Mark R. Klein, Berent Prakken, William W. Kwok, Eli Sercarz, Amnon Altman and Salvatore Albani

J Immunol March 15, 2005, 174 (6) 3204-3211; DOI: https://doi.org/10.4049/jimmunol.174.6.3204
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Impaired Cytolytic Activity in Calreticulin-Deficient CTLs
Simonetta Sipione, Catherine Ewen, Irene Shostak, Marek Michalak and R. Chris Bleackley

J Immunol March 15, 2005, 174 (6) 3212-3219; DOI: https://doi.org/10.4049/jimmunol.174.6.3212
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Mannose-Binding Lectin-Deficient Mice Display Defective Apoptotic Cell Clearance but No Autoimmune Phenotype
Lynda M. Stuart, Kazue Takahashi, Lei Shi, John Savill and R. Alan B. Ezekowitz

J Immunol March 15, 2005, 174 (6) 3220-3226; DOI: https://doi.org/10.4049/jimmunol.174.6.3220
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Heat Shock Protein 60 Inhibits Th1-Mediated Hepatitis Model via Innate Regulation of Th1/Th2 Transcription Factors and Cytokines
Alexandra Zanin-Zhorov, Rafael Bruck, Guy Tal, Shirly Oren, Hussein Aeed, Rami Hershkoviz, Irun R. Cohen and Ofer Lider

J Immunol March 15, 2005, 174 (6) 3227-3236; DOI: https://doi.org/10.4049/jimmunol.174.6.3227
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Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF-β-Bearing Regulatory Cells
Claudia Di Giacinto, Mariarosaria Marinaro, Massimo Sanchez, Warren Strober and Monica Boirivant

J Immunol March 15, 2005, 174 (6) 3237-3246; DOI: https://doi.org/10.4049/jimmunol.174.6.3237
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Very Low-Dose Tolerance with Nucleosomal Peptides Controls Lupus and Induces Potent Regulatory T Cell Subsets
Hee-Kap Kang, Marissa A. Michaels, Beate R. Berner and Syamal K. Datta

J Immunol March 15, 2005, 174 (6) 3247-3255; DOI: https://doi.org/10.4049/jimmunol.174.6.3247
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Protein Conformation Significantly Influences Immune Responses to Prion Protein
Azadeh Khalili-Shirazi, Sonia Quaratino, Marco Londei, Linda Summers, Mourad Tayebi, Anthony R. Clarke, Simon H. Hawke, Graham S. Jackson and John Collinge

J Immunol March 15, 2005, 174 (6) 3256-3263; DOI: https://doi.org/10.4049/jimmunol.174.6.3256
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Coligation of the B Cell Receptor with Complement Receptor Type 2 (CR2/CD21) Using Its Natural Ligand C3dg: Activation without Engagement of an Inhibitory Signaling Pathway
Taras Lyubchenko, Joe Dal Porto, John C. Cambier and V. Michael Holers

J Immunol March 15, 2005, 174 (6) 3264-3272; DOI: https://doi.org/10.4049/jimmunol.174.6.3264
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Exacerbation of Granuloma Formation in IL-1 Receptor Antagonist-Deficient Mice with Impaired Dendritic Cell Maturation Associated with Th2 Cytokine Production
Hisashi Iizasa, Hiroyuki Yoneyama, Naofumi Mukaida, Yuki Katakoka, Makoto Naito, Nobuaki Yoshida, Emi Nakashima and Kouji Matsushima

J Immunol March 15, 2005, 174 (6) 3273-3280; DOI: https://doi.org/10.4049/jimmunol.174.6.3273
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Δ-9-Tetrahydrocannabinol Enhances Breast Cancer Growth and Metastasis by Suppression of the Antitumor Immune Response
Robert J. McKallip, Mitzi Nagarkatti and Prakash S. Nagarkatti

J Immunol March 15, 2005, 174 (6) 3281-3289; DOI: https://doi.org/10.4049/jimmunol.174.6.3281
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The Generation of CD25⁺CD4⁺ Regulatory T Cells That Prevent Allograft Rejection Does Not Compromise Immunity to a Viral Pathogen
Andrew Bushell, Emma Jones, Awen Gallimore and Kathryn Wood

J Immunol March 15, 2005, 174 (6) 3290-3297; DOI: https://doi.org/10.4049/jimmunol.174.6.3290
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CD38 Controls ADP-Ribosyltransferase-2-Catalyzed ADP-Ribosylation of T Cell Surface Proteins
Christian Krebs, Sahil Adriouch, Fenja Braasch, Wolfgang Koestner, Edward H. Leiter, Michel Seman, Frances E. Lund, Norman Oppenheimer, Friedrich Haag and Friedrich Koch-Nolte

J Immunol March 15, 2005, 174 (6) 3298-3305; DOI: https://doi.org/10.4049/jimmunol.174.6.3298
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Identification of Stimulating and Inhibitory Epitopes within the Heat Shock Protein 70 Molecule That Modulate Cytokine Production and Maturation of Dendritic Cells
Yufei Wang, Trevor Whittall, Edward McGowan, Justine Younson, Charles Kelly, Lesley A. Bergmeier, Mahavir Singh and Thomas Lehner

J Immunol March 15, 2005, 174 (6) 3306-3316; DOI: https://doi.org/10.4049/jimmunol.174.6.3306
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The Immunogenicity of Dendritic Cell-Based Vaccines Is Not Hampered by Doxorubicin and Melphalan Administration
Anna Casati, Valérie S. Zimmermann, Fabio Benigni, Maria T. S. Bertilaccio, Matteo Bellone and Anna Mondino

J Immunol March 15, 2005, 174 (6) 3317-3325; DOI: https://doi.org/10.4049/jimmunol.174.6.3317
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Nucleosome, the Main Autoantigen in Systemic Lupus Erythematosus, Induces Direct Dendritic Cell Activation via a MyD88-Independent Pathway: Consequences on Inflammation
Patrice Decker, Harpreet Singh-Jasuja, Sabine Haager, Ina Kötter and Hans-Georg Rammensee

J Immunol March 15, 2005, 174 (6) 3326-3334; DOI: https://doi.org/10.4049/jimmunol.174.6.3326
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Mechanisms That Limit the In Vitro Proliferative Potential of Human CD8⁺ T Lymphocytes
Marco Migliaccio, Kenneth Raj, Olivier Menzel and Nathalie Rufer

J Immunol March 15, 2005, 174 (6) 3335-3343; DOI: https://doi.org/10.4049/jimmunol.174.6.3335
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Regulatory T Cells Suppress CD8⁺ T Cell Responses Induced by Direct Priming and Cross-Priming and Moderate Immunodominance Disparities
S. M. Mansour Haeryfar, Richard J. DiPaolo, David C. Tscharke, Jack R. Bennink and Jonathan W. Yewdell

J Immunol March 15, 2005, 174 (6) 3344-3351; DOI: https://doi.org/10.4049/jimmunol.174.6.3344
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Amelioration of Established Experimental Autoimmune Encephalomyelitis by an MHC Anchor-Substituted Variant of Proteolipid Protein 139–151
Carrie D. Margot, Mandy L. Ford and Brian D. Evavold

J Immunol March 15, 2005, 174 (6) 3352-3358; DOI: https://doi.org/10.4049/jimmunol.174.6.3352
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Opposing Roles for the Cyclin-Dependent Kinase Inhibitor p27^kip1 in the Control of CD4⁺ T Cell Proliferation and Effector Function
Emily A. Rowell, Matthew C. Walsh and Andrew D. Wells

J Immunol March 15, 2005, 174 (6) 3359-3368; DOI: https://doi.org/10.4049/jimmunol.174.6.3359
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B Cell Receptor (BCR) Cross-Talk: CD40 Engagement Enhances BCR-Induced ERK Activation
Takuya Mizuno and Thomas L. Rothstein

J Immunol March 15, 2005, 174 (6) 3369-3376; DOI: https://doi.org/10.4049/jimmunol.174.6.3369
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B and T Lymphocyte Attenuator Exhibits Structural and Expression Polymorphisms and Is Highly Induced in Anergic CD4⁺ T Cells
Michelle A. Hurchla, John R. Sedy, Maya Gavrielli, Charles G. Drake, Theresa L. Murphy and Kenneth M. Murphy

J Immunol March 15, 2005, 174 (6) 3377-3385; DOI: https://doi.org/10.4049/jimmunol.174.6.3377
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γδ T Cell Function Varies with the Expressed WC1 Coreceptor
Aric N. Rogers, Denille G. VanBuren, Emmett E. Hedblom, Mulualem E. Tilahun, Janice C. Telfer and Cynthia L. Baldwin

J Immunol March 15, 2005, 174 (6) 3386-3393; DOI: https://doi.org/10.4049/jimmunol.174.6.3386
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Small Rho GTPases Regulate Antigen Presentation in Dendritic Cells
Galina V. Shurin, Irina L. Tourkova, Gurkamal S. Chatta, Gudula Schmidt, Sheng Wei, Julie Y. Djeu and Michael R. Shurin

J Immunol March 15, 2005, 174 (6) 3394-3400; DOI: https://doi.org/10.4049/jimmunol.174.6.3394
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The Role of Intercellular Adhesion Molecule-1/LFA-1 Interactions in the Generation of Tumor-Specific CD8⁺ T Cell Responses
S. Rhiannon Jenkinson, Neil A. Williams and David J. Morgan

J Immunol March 15, 2005, 174 (6) 3401-3407; DOI: https://doi.org/10.4049/jimmunol.174.6.3401
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Role of the Programmed Death-1 Pathway in Regulation of Alloimmune Responses In Vivo
Sigrid E. Sandner, Michael R. Clarkson, Alan D. Salama, Alberto Sanchez-Fueyo, Christoph Domenig, Antje Habicht, Nader Najafian, Hideo Yagita, Miyuki Azuma, Laurence A. Turka and Mohamed H. Sayegh

J Immunol March 15, 2005, 174 (6) 3408-3415; DOI: https://doi.org/10.4049/jimmunol.174.6.3408
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ICAM-1 Contributes to but Is Not Essential for Tumor Antigen Cross-Priming and CD8⁺ T Cell-Mediated Tumor Rejection In Vivo
Christian Blank, Ian Brown, Aalok K. Kacha, Mary A. Markiewicz and Thomas F. Gajewski

J Immunol March 15, 2005, 174 (6) 3416-3420; DOI: https://doi.org/10.4049/jimmunol.174.6.3416
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Quantitating Effector and Regulatory T Lymphocytes in Immune Responses by Limiting Dilution Analysis Modeling
Thierry Bonnefoix, Philippe Bonnefoix, Pascal Perron, Jian-Qing Mi, Wan Fai Ng, Robert Lechler, Jean-Claude Bensa, Jean-Yves Cahn and Dominique Leroux

J Immunol March 15, 2005, 174 (6) 3421-3431; DOI: https://doi.org/10.4049/jimmunol.174.6.3421
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Cross-Priming of T Cell Responses by Synthetic Microspheres Carrying a CD8⁺ T Cell Epitope Requires an Adjuvant Signal
Florence Boisgérault, Paloma Rueda, Cheng Ming Sun, Sandra Hervas-Stubbs, Marie Rojas and Claude Leclerc

J Immunol March 15, 2005, 174 (6) 3432-3439; DOI: https://doi.org/10.4049/jimmunol.174.6.3432
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A Role for Caspases in Controlling IL-4 Expression in T Cells
Sarita Sehra, Dipak Patel, Saritha Kusam, Zheng-Yu Wang, Cheong-Hee Chang and Alexander L. Dent

J Immunol March 15, 2005, 174 (6) 3440-3446; DOI: https://doi.org/10.4049/jimmunol.174.6.3440
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Transplantation Tolerance in NF-κB-Impaired Mice Is Not Due to Regulation but Is Prevented by Transgenic Expression of Bcl-x_L
Ping Zhou, Samuel J. Balin, Mona Mashayekhi, Kwang Woo Hwang, David A. Palucki and Maria-Luisa Alegre

J Immunol March 15, 2005, 174 (6) 3447-3453; DOI: https://doi.org/10.4049/jimmunol.174.6.3447
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VH1–46 Is the Dominant Immunoglobulin Heavy Chain Gene Segment in Rotavirus-Specific Memory B Cells Expressing the Intestinal Homing Receptor α₄β₇
Jörn-Hendrik Weitkamp, Nicole L. Kallewaard, Amber L. Bowen, Bonnie J. LaFleur, Harry B. Greenberg and James E. Crowe Jr

J Immunol March 15, 2005, 174 (6) 3454-3460; DOI: https://doi.org/10.4049/jimmunol.174.6.3454
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Cryptococcus neoformans Capsular Glucuronoxylomannan Induces Expression of Fas Ligand in Macrophages
Claudia Monari, Eva Pericolini, Giovanni Bistoni, Arturo Casadevall, Thomas R. Kozel and Anna Vecchiarelli

J Immunol March 15, 2005, 174 (6) 3461-3468; DOI: https://doi.org/10.4049/jimmunol.174.6.3461

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Solvent Accessibility of Native and Hydrolyzed Human Complement Protein 3 Analyzed by Hydrogen/Deuterium Exchange and Mass Spectrometry
Michael S. Winters, Daniel S. Spellman and John D. Lambris

J Immunol March 15, 2005, 174 (6) 3469-3474; DOI: https://doi.org/10.4049/jimmunol.174.6.3469
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Characterization of the Chicken C-Type Lectin-Like Receptors B-NK and B-lec Suggests That the NK Complex and the MHC Share a Common Ancestral Region
Sally L. Rogers, Thomas W. Göbel, Birgit C. Viertlboeck, Sarah Milne, Stephan Beck and Jim Kaufman

J Immunol March 15, 2005, 174 (6) 3475-3483; DOI: https://doi.org/10.4049/jimmunol.174.6.3475
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The Protooncogene c-Maf Is an Essential Transcription Factor for IL-10 Gene Expression in Macrophages
Shanjin Cao, Jianguo Liu, Lihua Song and Xiaojing Ma

J Immunol March 15, 2005, 174 (6) 3484-3492; DOI: https://doi.org/10.4049/jimmunol.174.6.3484
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Genes “Waiting” for Recruitment by the Adaptive Immune System: The Insights from Amphioxus
Cuiling Yu, Meiling Dong, Xiaokun Wu, Shengguo Li, Shengfeng Huang, Jing Su, Jianwen Wei, Yang Shen, Chunyan Mou, Xiaojin Xie, Jianghai Lin, Shaochun Yuan, Xuesong Yu, Yanhong Yu, Jingchun Du, Shicui Zhang, Xuanxian Peng, Mengqing Xiang and Anlong Xu

J Immunol March 15, 2005, 174 (6) 3493-3500; DOI: https://doi.org/10.4049/jimmunol.174.6.3493
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Molecular Basis for the High Affinity Interaction between the Thymic Leukemia Antigen and the CD8αα Molecule
Antoine Attinger, Lesley Devine, Yiran Wang-Zhu, Donald Martin, Jia-huai Wang, Ellis L. Reinherz, Mitchell Kronenberg, Hilde Cheroutre and Paula Kavathas

J Immunol March 15, 2005, 174 (6) 3501-3507; DOI: https://doi.org/10.4049/jimmunol.174.6.3501
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Lipid Rafts Associate with Intracellular B Cell Receptors and Exhibit a B Cell Stage-Specific Protein Composition
Dirk Mielenz, Christian Vettermann, Martin Hampel, Christiane Lang, Athanasia Avramidou, Michael Karas and Hans-Martin Jäck

J Immunol March 15, 2005, 174 (6) 3508-3517; DOI: https://doi.org/10.4049/jimmunol.174.6.3508
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A Splice Variant of the TCR ζ mRNA Lacking Exon 7 Leads to the Down-Regulation of TCR ζ, the TCR/CD3 Complex, and IL-2 Production in Systemic Lupus Erythematosus T Cells
Kensei Tsuzaka, Yumiko Setoyama, Keiko Yoshimoto, Kiyono Shiraishi, Katsuya Suzuki, Tohru Abe and Tsutomu Takeuchi

J Immunol March 15, 2005, 174 (6) 3518-3525; DOI: https://doi.org/10.4049/jimmunol.174.6.3518

IMMUNOGENETICS

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Functional Domains of Runx1 Are Differentially Required for CD4 Repression, TCRβ Expression, and CD4/8 Double-Negative to CD4/8 Double-Positive Transition in Thymocyte Development
Masahito Kawazu, Takashi Asai, Motoshi Ichikawa, Go Yamamoto, Toshiki Saito, Susumu Goyama, Kinuko Mitani, Kohei Miyazono, Shigeru Chiba, Seishi Ogawa, Mineo Kurokawa and Hisamaru Hirai

J Immunol March 15, 2005, 174 (6) 3526-3533; DOI: https://doi.org/10.4049/jimmunol.174.6.3526

HOST DEFENSE

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The IL-27 Receptor Chain WSX-1 Differentially Regulates Antibacterial Immunity and Survival during Experimental Tuberculosis
Christoph Hölscher, Alexandra Hölscher, Dominik Rückerl, Takayuki Yoshimoto, Hiroki Yoshida, Tak Mak, Christiaan Saris and Stefan Ehlers

J Immunol March 15, 2005, 174 (6) 3534-3544; DOI: https://doi.org/10.4049/jimmunol.174.6.3534
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Neisserial Porin-Induced Dendritic Cell Activation Is MyD88 and TLR2 Dependent
Theresa E. Singleton, Paola Massari and Lee M. Wetzler

J Immunol March 15, 2005, 174 (6) 3545-3550; DOI: https://doi.org/10.4049/jimmunol.174.6.3545
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Sphingosine Kinase 1 (SK1) Is Recruited to Nascent Phagosomes in Human Macrophages: Inhibition of SK1 Translocation by Mycobacterium tuberculosis
Christopher R. Thompson, Shankar S. Iyer, Natalie Melrose, Rebecca VanOosten, Korey Johnson, Stuart M. Pitson, Lina M. Obeid and David J. Kusner

J Immunol March 15, 2005, 174 (6) 3551-3561; DOI: https://doi.org/10.4049/jimmunol.174.6.3551
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Burkholderia cenocepacia Induces Neutrophil Necrosis in Chronic Granulomatous Disease
Johan Bylund, Paul A. Campsall, Rebecca C. Ma, Barbara-Ann D. Conway and David P. Speert

J Immunol March 15, 2005, 174 (6) 3562-3569; DOI: https://doi.org/10.4049/jimmunol.174.6.3562
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Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium tuberculosis on the Interaction between Mycobacteria and the Host Immune System
Laleh Majlessi, Priscille Brodin, Roland Brosch, Marie-Jésus Rojas, Huot Khun, Michel Huerre, Stewart T. Cole and Claude Leclerc

J Immunol March 15, 2005, 174 (6) 3570-3579; DOI: https://doi.org/10.4049/jimmunol.174.6.3570
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Reovirus Serotype 1/Strain Lang-Stimulated Activation of Antigen-Specific T Lymphocytes in Peyer’s Patches and Distal Gut-Mucosal Sites: Activation Status and Cytotoxic Mechanisms
Mantej S. Bharhani, Jasvir S. Grewal, Mark J. Pilgrim, Candace Enocksen, Richard Peppler, Lucille London and Steven D. London

J Immunol March 15, 2005, 174 (6) 3580-3589; DOI: https://doi.org/10.4049/jimmunol.174.6.3580
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A Novel Role of IL-15 in Early Activation of Memory CD8⁺ CTL after Reinfection
Toshiki Yajima, Hitoshi Nishimura, Subash Sad, Hao Shen, Hiroyuki Kuwano and Yasunobu Yoshikai

J Immunol March 15, 2005, 174 (6) 3590-3597; DOI: https://doi.org/10.4049/jimmunol.174.6.3590
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Mechanisms of the Natural Reactivity of Lymphocytes from Noninfected Individuals to Membrane-Associated Leishmania infantum Antigens
Atfa Sassi, Beya Larguèche-Darwaz, Alexis Collette, Adrien Six, Dhafer Laouini, Pierre André Cazenave and Koussay Dellagi

J Immunol March 15, 2005, 174 (6) 3598-3607; DOI: https://doi.org/10.4049/jimmunol.174.6.3598

INFLAMMATION

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Intracellular IL-1 Receptor Antagonist Type 1 Inhibits IL-1-Induced Cytokine Production in Keratinocytes through Binding to the Third Component of the COP9 Signalosome
Nirmal K. Banda, Carla Guthridge, Devon Sheppard, Kelly S. Cairns, Michele Muggli, Dawadschargal Bech-Otschir, Wolfgang Dubiel and William P. Arend

J Immunol March 15, 2005, 174 (6) 3608-3616; DOI: https://doi.org/10.4049/jimmunol.174.6.3608
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Involvement of BLT1 Endocytosis and Yes Kinase Activation in Leukotriene B₄-Induced Neutrophil Degranulation
Eric Gaudreault, Charles Thompson, Jana Stankova and Marek Rola-Pleszczynski

J Immunol March 15, 2005, 174 (6) 3617-3625; DOI: https://doi.org/10.4049/jimmunol.174.6.3617
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Stem Cell Factor Has a Suppressive Activity to IgE-Mediated Chemotaxis of Mast Cells
Junko Sawada, Shinya Shimizu, Takuya Tamatani, Shiro Kanegasaki, Hirohisa Saito, Akane Tanaka, Naotomo Kambe, Tatsutoshi Nakahata and Hiroshi Matsuda

J Immunol March 15, 2005, 174 (6) 3626-3632; DOI: https://doi.org/10.4049/jimmunol.174.6.3626
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Inhibition of Neutrophil Apoptosis by TLR Agonists in Whole Blood: Involvement of the Phosphoinositide 3-Kinase/Akt and NF-κB Signaling Pathways, Leading to Increased Levels of Mcl-1, A1, and Phosphorylated Bad
Stéphanie François, Jamel El Benna, Pham M. C. Dang, Eric Pedruzzi, Marie-Anne Gougerot-Pocidalo and Carole Elbim

J Immunol March 15, 2005, 174 (6) 3633-3642; DOI: https://doi.org/10.4049/jimmunol.174.6.3633
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Pyocyanin Production by Pseudomonas aeruginosa Induces Neutrophil Apoptosis and Impairs Neutrophil-Mediated Host Defenses In Vivo
Lucy Allen, David H. Dockrell, Theresa Pattery, Daniel G. Lee, Pierre Cornelis, Paul G. Hellewell and Moira K. B. Whyte

J Immunol March 15, 2005, 174 (6) 3643-3649; DOI: https://doi.org/10.4049/jimmunol.174.6.3643
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The Nuclear IκB Protein IκBNS Selectively Inhibits Lipopolysaccharide-Induced IL-6 Production in Macrophages of the Colonic Lamina Propria
Tomonori Hirotani, Pui Y. Lee, Hirotaka Kuwata, Masahiro Yamamoto, Makoto Matsumoto, Ichiro Kawase, Shizuo Akira and Kiyoshi Takeda

J Immunol March 15, 2005, 174 (6) 3650-3657; DOI: https://doi.org/10.4049/jimmunol.174.6.3650
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Helicobacter pylori Disrupts NADPH Oxidase Targeting in Human Neutrophils to Induce Extracellular Superoxide Release
Lee-Ann H. Allen, Benjamin R. Beecher, Jeffrey T. Lynch, Olga V. Rohner and Lara M. Wittine

J Immunol March 15, 2005, 174 (6) 3658-3667; DOI: https://doi.org/10.4049/jimmunol.174.6.3658
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Manifestations of Inflammatory Arthritis Are Critically Dependent on LFA-1
Gerald M. Watts, Frank J. M. Beurskens, Ines Martin-Padura, Christie M. Ballantyne, Lloyd B. Klickstein, Michael B. Brenner and David M. Lee

J Immunol March 15, 2005, 174 (6) 3668-3675; DOI: https://doi.org/10.4049/jimmunol.174.6.3668
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Febrile-Range Hyperthermia Augments Neutrophil Accumulation and Enhances Lung Injury in Experimental Gram-Negative Bacterial Pneumonia
Penelope Rice, Erica Martin, Ju-Ren He, Mariah Frank, Louis DeTolla, Lisa Hester, Timothy O’Neill, Cheu Manka, Ivor Benjamin, Ashish Nagarsekar, Ishwar Singh and Jeffrey D. Hasday

J Immunol March 15, 2005, 174 (6) 3676-3685; DOI: https://doi.org/10.4049/jimmunol.174.6.3676
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The Human Herpes Virus 8-Encoded Chemokine Receptor Is Required for Angioproliferation in a Murine Model of Kaposi’s Sarcoma
Kristian K. Jensen, Denise J. Manfra, Marcos G. Grisotto, Andrea P. Martin, Galya Vassileva, Kevin Kelley, Thue W. Schwartz and Sergio A. Lira

J Immunol March 15, 2005, 174 (6) 3686-3694; DOI: https://doi.org/10.4049/jimmunol.174.6.3686
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IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes
Katia Boniface, François-Xavier Bernard, Martine Garcia, Austin L. Gurney, Jean-Claude Lecron and Franck Morel

J Immunol March 15, 2005, 174 (6) 3695-3702; DOI: https://doi.org/10.4049/jimmunol.174.6.3695
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Activation of the Prostaglandin D₂ Receptor DP2/CRTH2 Increases Allergic Inflammation in Mouse
Isabelle Spik, Céline Brénuchon, Véronique Angéli, Delphine Staumont, Sébastien Fleury, Monique Capron, François Trottein and David Dombrowicz

J Immunol March 15, 2005, 174 (6) 3703-3708; DOI: https://doi.org/10.4049/jimmunol.174.6.3703
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Unconjugated Bilirubin Inhibits VCAM-1-Mediated Transendothelial Leukocyte Migration
Pavitra Keshavan, Tracy L. Deem, Sandy J. Schwemberger, George F. Babcock, Joan M. Cook-Mills and Stephen D. Zucker

J Immunol March 15, 2005, 174 (6) 3709-3718; DOI: https://doi.org/10.4049/jimmunol.174.6.3709
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The Cytokine IL-1β Activates IFN Response Factor 3 in Human Fetal Astrocytes in Culture
Mark A. Rivieccio, Gareth R. John, Xianyuan Song, Hyeon-Sook Suh, Yongmei Zhao, Sunhee C. Lee and Celia F. Brosnan

J Immunol March 15, 2005, 174 (6) 3719-3726; DOI: https://doi.org/10.4049/jimmunol.174.6.3719
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Modulation of Phagocytosis of Apoptotic Neutrophils by Supernatant from Dexamethasone-Treated Macrophages and Annexin-Derived Peptide Ac_2–26
Paola Maderna, Simon Yona, Mauro Perretti and Catherine Godson

J Immunol March 15, 2005, 174 (6) 3727-3733; DOI: https://doi.org/10.4049/jimmunol.174.6.3727
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Indispensable Role of Stat5a in Stat6-Independent Th2 Cell Differentiation and Allergic Airway Inflammation
Hiroaki Takatori, Hiroshi Nakajima, Koichi Hirose, Shin-ichiro Kagami, Tomohiro Tamachi, Akira Suto, Kotaro Suzuki, Yasushi Saito and Itsuo Iwamoto

J Immunol March 15, 2005, 174 (6) 3734-3740; DOI: https://doi.org/10.4049/jimmunol.174.6.3734

CLINICAL IMMUNOLOGY

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Alloreactive T Cell Responses and Acute Rejection of Single Class II MHC-Disparate Heart Allografts Are under Strict Regulation by CD4⁺CD25⁺ T Cells
Soren Schenk, Danielle D. Kish, Chunshui He, Tarek El-Sawy, Eise Chiffoleau, Chuangqui Chen, Zihao Wu, Sigrid Sandner, Anton V. Gorbachev, Kiyotaka Fukamachi, Peter S. Heeger, Mohamed H. Sayegh, Laurence A. Turka and Robert L. Fairchild

J Immunol March 15, 2005, 174 (6) 3741-3748; DOI: https://doi.org/10.4049/jimmunol.174.6.3741
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B Cell Response to Surface IgM Cross-Linking Identifies Different Prognostic Groups of B-Chronic Lymphocytic Leukemia Patients
Steven Nédellec, Yves Renaudineau, Anne Bordron, Christian Berthou, Nina Porakishvili, Peter M. Lydyard, Jacques-Olivier Pers and Pierre Youinou

J Immunol March 15, 2005, 174 (6) 3749-3756; DOI: https://doi.org/10.4049/jimmunol.174.6.3749
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Differential Regulation of Granzyme and Perforin in Effector and Memory T Cells following Smallpox Immunization
Michael T. Rock, Sandra M. Yoder, Peter F. Wright, Thomas R. Talbot, Kathryn M. Edwards and James E. Crowe Jr

J Immunol March 15, 2005, 174 (6) 3757-3764; DOI: https://doi.org/10.4049/jimmunol.174.6.3757
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Prolonged Lymphopenia, Lymphoid Depletion, and Hypoprolactinemia in Children with Nosocomial Sepsis and Multiple Organ Failure
Kate A. Felmet, Mark W. Hall, Robert S. B. Clark, Ronald Jaffe and Joseph A. Carcillo

J Immunol March 15, 2005, 174 (6) 3765-3772; DOI: https://doi.org/10.4049/jimmunol.174.6.3765
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CD1a and CD1c Activate Intrathyroidal T Cells during Graves’ Disease and Hashimoto’s Thyroiditis
Carme Roura-Mir, Marta Catálfamo, Tan-Yun Cheng, Ellen Marqusee, Gurdyal S. Besra, Dolores Jaraquemada and D. Branch Moody

J Immunol March 15, 2005, 174 (6) 3773-3780; DOI: https://doi.org/10.4049/jimmunol.174.6.3773
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Antigen-Specific B Cells Are Required as APCs and Autoantibody-Producing Cells for Induction of Severe Autoimmune Arthritis
Shannon K. O’Neill, Mark J. Shlomchik, Tibor T. Glant, Yanxia Cao, Paul D. Doodes and Alison Finnegan

J Immunol March 15, 2005, 174 (6) 3781-3788; DOI: https://doi.org/10.4049/jimmunol.174.6.3781
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IL-10-Dependent Suppression of Experimental Allergic Encephalomyelitis by Th2-Differentiated, Anti-TCR Redirected T Lymphocytes
Divya J. Mekala, Rajshekhar S. Alli and Terrence L. Geiger

J Immunol March 15, 2005, 174 (6) 3789-3797; DOI: https://doi.org/10.4049/jimmunol.174.6.3789
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Telomerase mRNA-Transfected Dendritic Cells Stimulate Antigen-Specific CD8⁺ and CD4⁺ T Cell Responses in Patients with Metastatic Prostate Cancer
Zhen Su, Jens Dannull, Benjamin K. Yang, Philipp Dahm, Doris Coleman, Donna Yancey, Sylvia Sichi, Donna Niedzwiecki, David Boczkowski, Eli Gilboa and Johannes Vieweg

J Immunol March 15, 2005, 174 (6) 3798-3807; DOI: https://doi.org/10.4049/jimmunol.174.6.3798
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Immunization with Lentiviral Vector-Transduced Dendritic Cells Induces Strong and Long-Lasting T Cell Responses and Therapeutic Immunity
Yukai He, Jiying Zhang, Zhibao Mi, Paul Robbins and Louis D. Falo Jr

J Immunol March 15, 2005, 174 (6) 3808-3817; DOI: https://doi.org/10.4049/jimmunol.174.6.3808

CORRECTIONS

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Mature Human Langerhans Cells Derived from CD34⁺ Hematopoietic Progenitors Stimulate Greater Cytolytic T Lymphocyte Activity in the Absence of Bioactive IL-12p70, by Either Single Peptide Presentation or Cross-Priming, Than Do Dermal-Interstitial or Monocyte-Derived Dendritic Cells.
Gundrun Ratzinger, Jan Baggers, Maria A. de Cos, Jianda Yuan, Tao Dao, John L. Reagan, Christian Münz, Glenn Heller and James W. Young

J Immunol March 15, 2005, 174 (6) 3818; DOI: https://doi.org/10.4049/jimmunol.174.6.3818
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Crucial Role of Inhibitor of DNA Binding/Differentiation in the Vascular Endothelial Growth Factor-Induced Activation and Angiogenic Processes of Human Endothelial Cells.
Daisuke Sakurai, Naoyuki Tsuchiya, Akihiro Yamaguchi, Yurai Okaji, Nelson H. Tsuno, Tetsuji Kobata, Koki Takahashi and Katsushi Tokunaga

J Immunol March 15, 2005, 174 (6) 3818; DOI: https://doi.org/10.4049/jimmunol.174.6.3818-a
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Fas Death Receptor Signaling Represses Monocyte Numbers and Macrophage Activation In Vivo.
Nathaniel J. Brown, Jack Hutcheson, Emily Bickel, John C. Scatizzi, Lee D. Albee, G. Kenneth Haines III, Joy Eslick, Kathleen Bradley, Elsa Taricone and Harris Perlman

J Immunol March 15, 2005, 174 (6) 3818; DOI: https://doi.org/10.4049/jimmunol.174.6.3818-b
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Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge.
Neil Taylor, Karen McConnachie, Claudia Calder, Rosemary Dawson, Andrew Dick, Jonathon D. Sedgwick and Janet Liversidge

J Immunol March 15, 2005, 174 (6) 3818; DOI: https://doi.org/10.4049/jimmunol.174.6.3818-c

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IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

IMMUNOGENETICS

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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