The Journal of Immunology: 173 (11)

December 1, 2004; Volume 173,Issue 11

IN THIS ISSUE

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IN THIS ISSUE

J Immunol December 1, 2004, 173 (11) 6499-6500; DOI: https://doi.org/10.4049/jimmunol.173.11.6499

PILLARS OF IMMUNOLOGY

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Multiple Genes, One Polypeptide Chain
J. Donald Capra

J Immunol December 1, 2004, 173 (11) 6501-6502; DOI: https://doi.org/10.4049/jimmunol.173.11.6501
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Pillars Article: An Immunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA: V_H, D and J_H. Cell, 1980, 19: 981–992.
P. Early, H. Huang, M. Davis, K. Calame and L. Hood

J Immunol December 1, 2004, 173 (11) 6503-6514;

BRIEF REVIEWS

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The Fourth Way? Harnessing Aggressive Tendencies in the Thymus
Troy A. Baldwin, Kristin A. Hogquist and Stephen C. Jameson

J Immunol December 1, 2004, 173 (11) 6515-6520; DOI: https://doi.org/10.4049/jimmunol.173.11.6515

CUTTING EDGE

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Cutting Edge: Neutrophil Granulocyte Serves as a Vector for Leishmania Entry into Macrophages
Ger van Zandbergen, Matthias Klinger, Antje Mueller, Sonja Dannenberg, Andreas Gebert, Werner Solbach and Tamás Laskay

J Immunol December 1, 2004, 173 (11) 6521-6525; DOI: https://doi.org/10.4049/jimmunol.173.11.6521
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Cutting Edge: TGF-β Signaling Is Required for the In Vivo Expansion and Immunosuppressive Capacity of Regulatory CD4⁺CD25⁺ T Cells
Samuel Huber, Christoph Schramm, Hans A. Lehr, Amrit Mann, Steffen Schmitt, Christoph Becker, Martina Protschka, Peter R. Galle, Markus F. Neurath and Manfred Blessing

J Immunol December 1, 2004, 173 (11) 6526-6531; DOI: https://doi.org/10.4049/jimmunol.173.11.6526
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Cutting Edge: TCR Revision Occurs in Germinal Centers
Cristine J. Cooper, Gail L. Turk, Mingyi Sun, Andrew G. Farr and Pamela J. Fink

J Immunol December 1, 2004, 173 (11) 6532-6536; DOI: https://doi.org/10.4049/jimmunol.173.11.6532
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Cutting Edge: Transpresentation of IL-15 by Bone Marrow-Derived Cells Necessitates Expression of IL-15 and IL-15Rα by the Same Cells
Michelle M. Sandau, Kimberly S. Schluns, Leo Lefrancois and Stephen C. Jameson

J Immunol December 1, 2004, 173 (11) 6537-6541; DOI: https://doi.org/10.4049/jimmunol.173.11.6537
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Cutting Edge: A Critical Role for CD70 in CD8 T Cell Priming by CD40-Licensed APCs
Vadim Y. Taraban, Tania F. Rowley and Aymen Al-Shamkhani

J Immunol December 1, 2004, 173 (11) 6542-6546; DOI: https://doi.org/10.4049/jimmunol.173.11.6542

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Novel Insights on Human NK Cells’ Immunological Modalities Revealed by Gene Expression Profiling
Jacob Hanna, Pamela Bechtel, Yufeng Zhai, Fadi Youssef, Karen McLachlan and Ofer Mandelboim

J Immunol December 1, 2004, 173 (11) 6547-6563; DOI: https://doi.org/10.4049/jimmunol.173.11.6547
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The Solvent-Inaccessible Cys⁶⁷ Residue of HLA-B27 Contributes to T Cell Recognition of HLA-B27/Peptide Complexes
Heiner Appel, Wolfgang Kuon, Maren Kuhne, Martin Hülsmeyer, Simon Kollnberger, Stefanie Kuhlmann, Elisabeth Weiss, Martin Zeitz, Kai Wucherpfennig, Paul Bowness and Joachim Sieper

J Immunol December 1, 2004, 173 (11) 6564-6573; DOI: https://doi.org/10.4049/jimmunol.173.11.6564
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“Pruning” of Alloreactive CD4⁺ T Cells Using 5- (and 6-)Carboxyfluorescein Diacetate Succinimidyl Ester Prolongs Skin Allograft Survival
Debbie Watson, Geoff Yu Zhang, Mary Sartor and Stephen I. Alexander

J Immunol December 1, 2004, 173 (11) 6574-6582; DOI: https://doi.org/10.4049/jimmunol.173.11.6574
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Pax5-Deficient Mice Exhibit Early Onset Osteopenia with Increased Osteoclast Progenitors
Mark C. Horowitz, Yougen Xi, David L. Pflugh, David G. T. Hesslein, David G. Schatz, Joseph A. Lorenzo and Alfred L. M. Bothwell

J Immunol December 1, 2004, 173 (11) 6583-6591; DOI: https://doi.org/10.4049/jimmunol.173.11.6583
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Plasmacytoid Dendritic Cell Recruitment by Immobilized CXCR3 Ligands
Norbert Kohrgruber, Marion Gröger, Paul Meraner, Ernst Kriehuber, Peter Petzelbauer, Sabine Brandt, Georg Stingl, Antal Rot and Dieter Maurer

J Immunol December 1, 2004, 173 (11) 6592-6602; DOI: https://doi.org/10.4049/jimmunol.173.11.6592
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Early and Quantal (by Litter) Expression of Insulin Autoantibodies in the Nonobese Diabetic Mice Predict Early Diabetes Onset
Evie Melanitou, Devasenan Devendra, Edwin Liu, Dongmei Miao and George S. Eisenbarth

J Immunol December 1, 2004, 173 (11) 6603-6610; DOI: https://doi.org/10.4049/jimmunol.173.11.6603
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The Contraction Phase of Virus-Specific CD8⁺ T Cells Is Unaffected by a Pan-Caspase Inhibitor
Alexander K. Nussbaum and J. Lindsay Whitton

J Immunol December 1, 2004, 173 (11) 6611-6618; DOI: https://doi.org/10.4049/jimmunol.173.11.6611
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Cellular FLIP (Long Isoform) Overexpression in T Cells Drives Th2 Effector Responses and Promotes Immunoregulation in Experimental Autoimmune Encephalomyelitis
Vivian Tseveleki, Jan Bauer, Era Taoufik, Chengmai Ruan, Leondios Leondiadis, Sylva Haralambous, Hans Lassmann and Lesley Probert

J Immunol December 1, 2004, 173 (11) 6619-6626; DOI: https://doi.org/10.4049/jimmunol.173.11.6619
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Following Immunization Antigen Becomes Concentrated in a Limited Number of APCs Including B Cells
Craig A. Byersdorfer, Richard J. DiPaolo, Shirley J. Petzold and Emil R. Unanue

J Immunol December 1, 2004, 173 (11) 6627-6634; DOI: https://doi.org/10.4049/jimmunol.173.11.6627
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IL-12 Gene Therapy Is an Effective Therapeutic Strategy for Hepatocellular Carcinoma in Immunosuppressed Mice
Noboru Harada, Mitsuo Shimada, Shinji Okano, Taketoshi Suehiro, Yuji Soejima, Yukihiro Tomita and Yoshihiko Maehara

J Immunol December 1, 2004, 173 (11) 6635-6644; DOI: https://doi.org/10.4049/jimmunol.173.11.6635
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Role of CTLA-4 in the Activation of Single- and Double-Positive Thymocytes
Hyokjoon Kwon, Hee-Sook Jun, Lee-Yong Khil and Ji-Won Yoon

J Immunol December 1, 2004, 173 (11) 6645-6653; DOI: https://doi.org/10.4049/jimmunol.173.11.6645
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Tolerance Induction by Veto CTLs in the TCR Transgenic 2C Mouse Model. I. Relative Reactivity of Different Veto Cells
Shlomit Reich-Zeliger, Esther Bachar-Lustig, Judith Gan and Yair Reisner

J Immunol December 1, 2004, 173 (11) 6654-6659; DOI: https://doi.org/10.4049/jimmunol.173.11.6654
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Tolerance Induction by Veto CTLs in the TCR Transgenic 2C Mouse Model. II. Deletion of Effector Cells by Fas-Fas Ligand Apoptosis
Shlomit Reich-Zeliger, Judith Gan, Esther Bachar-Lustig and Yair Reisner

J Immunol December 1, 2004, 173 (11) 6660-6666; DOI: https://doi.org/10.4049/jimmunol.173.11.6660
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IFNβ Accelerates Autoimmune Type 1 Diabetes in Nonobese Diabetic Mice and Breaks the Tolerance to β Cells in Nondiabetes-Prone Mice
Aurora Alba, M. Carmen Puertas, Jorge Carrillo, Raquel Planas, Rosa Ampudia, Xavier Pastor, Fatima Bosch, Ricardo Pujol-Borrell, Joan Verdaguer and Marta Vives-Pi

J Immunol December 1, 2004, 173 (11) 6667-6675; DOI: https://doi.org/10.4049/jimmunol.173.11.6667
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Follicular Dendritic Cells Produce IL-15 That Enhances Germinal Center B Cell Proliferation in Membrane-Bound Form
Chan-Sik Park, Sun-Ok Yoon, Richard J. Armitage and Yong Sung Choi

J Immunol December 1, 2004, 173 (11) 6676-6683; DOI: https://doi.org/10.4049/jimmunol.173.11.6676
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Impact of CCR7 on Priming and Distribution of Antiviral Effector and Memory CTL
Tobias Junt, Elke Scandella, Reinhold Förster, Philippe Krebs, Stefan Krautwald, Martin Lipp, Hans Hengartner and Burkhard Ludewig

J Immunol December 1, 2004, 173 (11) 6684-6693; DOI: https://doi.org/10.4049/jimmunol.173.11.6684
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Shortening the Infectious Period Does Not Alter Expansion of CD8 T Cells but Diminishes Their Capacity to Differentiate into Memory Cells
Matthew A. Williams and Michael J. Bevan

J Immunol December 1, 2004, 173 (11) 6694-6702; DOI: https://doi.org/10.4049/jimmunol.173.11.6694
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Molecular Characterization of a Novel Immune Receptor Restricted to the Monocytic Lineage
Helena Aguilar, Damiana Álvarez-Errico, Andrés C. García-Montero, Alberto Orfao, Joan Sayós and Miguel López-Botet

J Immunol December 1, 2004, 173 (11) 6703-6711; DOI: https://doi.org/10.4049/jimmunol.173.11.6703
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IL-19 Induced Th2 Cytokines and Was Up-Regulated in Asthma Patients
Sheng-Chin Liao, Yung-Chih Cheng, Yo-Ching Wang, Chiung-Wen Wang, San-Ming Yang, Chun-Keung Yu, Chi-Chang Shieh, Kuo-Chen Cheng, Meng-Feng Lee, Shyh-Ren Chiang, Jiunn-Min Shieh and Ming-Shi Chang

J Immunol December 1, 2004, 173 (11) 6712-6718; DOI: https://doi.org/10.4049/jimmunol.173.11.6712
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Phenotypic and Functional Characterization of CD4 T Cells Expressing Killer Ig-Like Receptors
Jeroen van Bergen, Allan Thompson, Arno van der Slik, Tom H. M. Ottenhoff, Jacobijn Gussekloo and Frits Koning

J Immunol December 1, 2004, 173 (11) 6719-6726; DOI: https://doi.org/10.4049/jimmunol.173.11.6719
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Individual Nonobese Diabetic Mice Exhibit Unique Patterns of CD8⁺ T Cell Reactivity to Three Islet Antigens, Including the Newly Identified Widely Expressed Dystrophia Myotonica Kinase
Scott M. Lieberman, Toshiyuki Takaki, Bingye Han, Pere Santamaria, David V. Serreze and Teresa P. DiLorenzo

J Immunol December 1, 2004, 173 (11) 6727-6734; DOI: https://doi.org/10.4049/jimmunol.173.11.6727
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Mechanisms for Macrophage-Mediated HIV-1 Induction
Krishnakumar Devadas, Neil J. Hardegen, Larry M. Wahl, Indira K. Hewlett, Kathleen A. Clouse, Kenneth M. Yamada and Subhash Dhawan

J Immunol December 1, 2004, 173 (11) 6735-6744; DOI: https://doi.org/10.4049/jimmunol.173.11.6735
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Antiapoptotic Microenvironment of Acute Myeloid Leukemia
Dragana Milojković, Stephen Devereux, Nigel B. Westwood, Ghulam J. Mufti, N. Shaun B. Thomas and Andrea G. S. Buggins

J Immunol December 1, 2004, 173 (11) 6745-6752; DOI: https://doi.org/10.4049/jimmunol.173.11.6745
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Activation of Dendritic Cells That Cross-Present Tumor-Derived Antigen Licenses CD8⁺ CTL to Cause Tumor Eradication
Geertje J. D. van Mierlo, Zita F. H. M. Boonman, Hélène M. H. Dumortier, Annemieke Th. den Boer, Marieke F. Fransen, Jan Nouta, Ellen I. H. van der Voort, Rienk Offringa, René E. M. Toes and Cornelis J. M. Melief

J Immunol December 1, 2004, 173 (11) 6753-6759; DOI: https://doi.org/10.4049/jimmunol.173.11.6753
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Recruitment of Uterine NK Cells: Induction of CXC Chemokine Ligands 10 and 11 in Human Endometrium by Estradiol and Progesterone
Charles L. Sentman, Sarah K. Meadows, Charles R. Wira and Mikael Eriksson

J Immunol December 1, 2004, 173 (11) 6760-6766; DOI: https://doi.org/10.4049/jimmunol.173.11.6760
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Characterization of Tumor Reactivity of Human Vγ9Vδ2 γδ T Cells In Vitro and in SCID Mice In Vivo
Dieter Kabelitz, Daniela Wesch, Elke Pitters and Margot Zöller

J Immunol December 1, 2004, 173 (11) 6767-6776; DOI: https://doi.org/10.4049/jimmunol.173.11.6767
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Presence of Diabetes-Inhibiting, Glutamic Acid Decarboxylase-Specific, IL-10-Dependent, Regulatory T Cells in Naive Nonobese Diabetic Mice
Sylvaine You, Cyndi Chen, Wen-Hui Lee, Todd Brusko, Mark Atkinson and Chih-Pin Liu

J Immunol December 1, 2004, 173 (11) 6777-6785; DOI: https://doi.org/10.4049/jimmunol.173.11.6777
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Molecular Mechanisms of CD200 Inhibition of Mast Cell Activation
Shuli Zhang, Holly Cherwinski, Jonathon D. Sedgwick and Joseph H. Phillips

J Immunol December 1, 2004, 173 (11) 6786-6793; DOI: https://doi.org/10.4049/jimmunol.173.11.6786

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Antibody Repertoire Development in Fetal and Neonatal Pigs. VII. Characterization of the Preimmune κ Light Chain Repertoire
John E. Butler, Nancy Wertz, Jishan Sun, Huang Wang, Patrick Chardon, Francois Piumi and Kevin Wells

J Immunol December 1, 2004, 173 (11) 6794-6805; DOI: https://doi.org/10.4049/jimmunol.173.11.6794
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Biochemical Analysis of the Regulatory T Cell Protein Lymphocyte Activation Gene-3 (LAG-3; CD223)
Nianyu Li, Creg J. Workman, Stefani M. Martin and Dario A. A. Vignali

J Immunol December 1, 2004, 173 (11) 6806-6812; DOI: https://doi.org/10.4049/jimmunol.173.11.6806
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Transporter Associated with Antigen Processing Preselection of Peptides Binding to the MHC: A Bioinformatic Evaluation
Irini Doytchinova, Shelley Hemsley and Darren R. Flower

J Immunol December 1, 2004, 173 (11) 6813-6819; DOI: https://doi.org/10.4049/jimmunol.173.11.6813
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SHIP2 Is Recruited to the Cell Membrane upon Macrophage Colony-Stimulating Factor (M-CSF) Stimulation and Regulates M-CSF-Induced Signaling
Yijie Wang, Rosemary J. Keogh, Melissa G. Hunter, Christina A. Mitchell, Randall S. Frey, Kamran Javaid, Asrar B. Malik, Stéphane Schurmans, Susheela Tridandapani and Clay B. Marsh

J Immunol December 1, 2004, 173 (11) 6820-6830; DOI: https://doi.org/10.4049/jimmunol.173.11.6820
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The Glycosylation of Human Serum IgD and IgE and the Accessibility of Identified Oligomannose Structures for Interaction with Mannan-Binding Lectin
James N. Arnold, Catherine M. Radcliffe, Mark R. Wormald, Louise Royle, David J. Harvey, Max Crispin, Raymond A. Dwek, Robert B. Sim and Pauline M. Rudd

J Immunol December 1, 2004, 173 (11) 6831-6840; DOI: https://doi.org/10.4049/jimmunol.173.11.6831
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The Membrane-Proximal Immunoreceptor Tyrosine-Based Inhibitory Motif Is Critical for the Inhibitory Signaling Mediated by Siglecs-7 and -9, CD33-Related Siglecs Expressed on Human Monocytes and NK Cells
Tony Avril, Helen Floyd, Frederic Lopez, Eric Vivier and Paul R. Crocker

J Immunol December 1, 2004, 173 (11) 6841-6849; DOI: https://doi.org/10.4049/jimmunol.173.11.6841

HOST DEFENSE

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A Novel Adjuvant for Mucosal Immunity to HIV-1 gp120 in Nonhuman Primates
Naoto Yoshino, Fabien X.-S. Lü, Kohtaro Fujihashi, Yukari Hagiwara, Kosuke Kataoka, Ding Lu, Linda Hirst, Mitsuo Honda, Frederik W. van Ginkel, Yoshifumi Takeda, Christopher J. Miller, Hiroshi Kiyono and Jerry R. McGhee

J Immunol December 1, 2004, 173 (11) 6850-6857; DOI: https://doi.org/10.4049/jimmunol.173.11.6850
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Gene Expression Profiling of Host Response in Models of Acute HIV Infection
Steven E. Bosinger, Karoline A. Hosiawa, Mark J. Cameron, Desmond Persad, Longsi Ran, Luoling Xu, Mohamed R. Boulassel, Monique Parenteau, Jocelyn Fournier, Erling W. Rud and David J. Kelvin

J Immunol December 1, 2004, 173 (11) 6858-6863; DOI: https://doi.org/10.4049/jimmunol.173.11.6858
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RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Inhibits HIV-1 Transcription in Monocytes/Macrophages and Is Decreased in Brain Tissue from Patients with AIDS
Eileen S. Lee, Parisa Kalantari, Shigeki Tsutsui, Alicia Klatt, Janet Holden, Pamela H. Correll, Christopher Power and Andrew J. Henderson

J Immunol December 1, 2004, 173 (11) 6864-6872; DOI: https://doi.org/10.4049/jimmunol.173.11.6864
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Activation of Virus-Specific CD8⁺ T Cells by Lipopolysaccharide-Induced IL-12 and IL-18
Hans-Peter Raué, James D. Brien, Erika Hammarlund and Mark K. Slifka

J Immunol December 1, 2004, 173 (11) 6873-6881; DOI: https://doi.org/10.4049/jimmunol.173.11.6873
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TLR-Independent Induction of Dendritic Cell Maturation and Adaptive Immunity by Negative-Strand RNA Viruses
Carolina B. López, Bruno Moltedo, Lena Alexopoulou, Laura Bonifaz, Richard A. Flavell and Thomas M. Moran

J Immunol December 1, 2004, 173 (11) 6882-6889; DOI: https://doi.org/10.4049/jimmunol.173.11.6882
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Viral Activation of Macrophages through TLR-Dependent and -Independent Pathways
Lene Malmgaard, Jesper Melchjorsen, Andrew G. Bowie, Søren C. Mogensen and Søren R. Paludan

J Immunol December 1, 2004, 173 (11) 6890-6898; DOI: https://doi.org/10.4049/jimmunol.173.11.6890
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Interaction between Complement Regulators and Streptococcus pyogenes: Binding of C4b-Binding Protein and Factor H/Factor H-Like Protein 1 to M18 Strains Involves Two Different Cell Surface Molecules
David Pérez-Caballero, Isabel García-Laorden, Guadalupe Cortés, Michael R. Wessels, Santiago Rodríguez de Córdoba and Sebastián Albertí

J Immunol December 1, 2004, 173 (11) 6899-6904; DOI: https://doi.org/10.4049/jimmunol.173.11.6899
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Human CD8⁺ T Cells Recognize the 60-kDa Cysteine-Rich Outer Membrane Protein from Chlamydia trachomatis
Ana L. Gervassi, Kenneth H. Grabstein, Peter Probst, Bruce Hess, Mark R. Alderson and Steven P. Fling

J Immunol December 1, 2004, 173 (11) 6905-6913; DOI: https://doi.org/10.4049/jimmunol.173.11.6905

INFLAMMATION

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Nitric Oxide Inhibits IgE-Dependent Cytokine Production and Fos and Jun Activation in Mast Cells
Beverley J. Davis, Brian F. Flanagan, Alasdair M. Gilfillan, Dean D. Metcalfe and John W. Coleman

J Immunol December 1, 2004, 173 (11) 6914-6920; DOI: https://doi.org/10.4049/jimmunol.173.11.6914
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Platelet-Activating Factor and Kinin-Dependent Vascular Leakage as a Novel Functional Activity of the Soluble Terminal Complement Complex
Fleur Bossi, Fabio Fischetti, Valentina Pellis, Roberta Bulla, Elisabetta Ferrero, Tom Eirik Mollnes, Domenico Regoli and Francesco Tedesco

J Immunol December 1, 2004, 173 (11) 6921-6927; DOI: https://doi.org/10.4049/jimmunol.173.11.6921
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A Novel Mechanism for TNF-α Regulation by p38 MAPK: Involvement of NF-κB with Implications for Therapy in Rheumatoid Arthritis
Jamie Campbell, Cathleen J. Ciesielski, Abigail E. Hunt, Nicole J. Horwood, Jonathan T. Beech, Louise A. Hayes, Agnes Denys, Marc Feldmann, Fionula M. Brennan and Brian M. J. Foxwell

J Immunol December 1, 2004, 173 (11) 6928-6937; DOI: https://doi.org/10.4049/jimmunol.173.11.6928
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CCR1 and CC Chemokine Ligand 5 Interactions Exacerbate Innate Immune Responses during Sepsis
Traci L. Ness, Kristin J. Carpenter, Jillian L. Ewing, Craig J. Gerard, Cory M. Hogaboam and Steven L. Kunkel

J Immunol December 1, 2004, 173 (11) 6938-6948; DOI: https://doi.org/10.4049/jimmunol.173.11.6938
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Interaction of Soluble Form of Recombinant Extracellular TLR4 Domain with MD-2 Enables Lipopolysaccharide Binding and Attenuates TLR4-Mediated Signaling
Naoki Hyakushima, Hiroaki Mitsuzawa, Chiaki Nishitani, Hitomi Sano, Koji Kuronuma, Masanori Konishi, Tetsuo Himi, Kensuke Miyake and Yoshio Kuroki

J Immunol December 1, 2004, 173 (11) 6949-6954; DOI: https://doi.org/10.4049/jimmunol.173.11.6949
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Prostaglandin E₂ Promotes the Survival of Bone Marrow-Derived Dendritic Cells
Evros Vassiliou, Vikas Sharma, Huie Jing, Farzad Sheibanie and Doina Ganea

J Immunol December 1, 2004, 173 (11) 6955-6964; DOI: https://doi.org/10.4049/jimmunol.173.11.6955
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RhoA/Rho-Associated Kinase Pathway Selectively Regulates Thrombin-Induced Intercellular Adhesion Molecule-1 Expression in Endothelial Cells via Activation of IκB Kinase β and Phosphorylation of RelA/p65
Khandaker N. Anwar, Fabeha Fazal, Asrar B. Malik and Arshad Rahman

J Immunol December 1, 2004, 173 (11) 6965-6972; DOI: https://doi.org/10.4049/jimmunol.173.11.6965
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Lipopolysaccharide Induces Matrix Metalloproteinase-9 Expression via a Mitochondrial Reactive Oxygen Species-p38 Kinase-Activator Protein-1 Pathway in Raw 264.7 Cells
Chang-Hoon Woo, Jae-Hyang Lim and Jae-Hong Kim

J Immunol December 1, 2004, 173 (11) 6973-6980; DOI: https://doi.org/10.4049/jimmunol.173.11.6973
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Immunity to the Extracellular Domain of Nogo-A Modulates Experimental Autoimmune Encephalomyelitis
Paulo Fontoura, Peggy P. Ho, Jason DeVoss, Binhai Zheng, Byung J. Lee, Brian A. Kidd, Hideki Garren, Raymond A. Sobel, William H. Robinson, Marc Tessier-Lavigne and Lawrence Steinman

J Immunol December 1, 2004, 173 (11) 6981-6992; DOI: https://doi.org/10.4049/jimmunol.173.11.6981
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Involvement of Eotaxin, Eosinophils, and Pancreatic Predisposition in Development of Type 1 Diabetes Mellitus in the BioBreeding Rat
Martin J. Hessner, Xujing Wang, Lisa Meyer, Rhonda Geoffrey, Shuang Jia, Jessica Fuller, Ake Lernmark and Soumitra Ghosh

J Immunol December 1, 2004, 173 (11) 6993-7002; DOI: https://doi.org/10.4049/jimmunol.173.11.6993
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NF-κB Activation in Airways Modulates Allergic Inflammation but Not Hyperresponsiveness
Matthew E. Poynter, Roy Cloots, Tiest van Woerkom, Kelly J. Butnor, Pamela Vacek, Douglas J. Taatjes, Charles G. Irvin and Yvonne M. W. Janssen-Heininger

J Immunol December 1, 2004, 173 (11) 7003-7009; DOI: https://doi.org/10.4049/jimmunol.173.11.7003

CLINICAL IMMUNOLOGY

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Inhibition of Fractalkine Ameliorates Murine Collagen-Induced Arthritis
Toshihiro Nanki, Yasuyo Urasaki, Toshio Imai, Miyuki Nishimura, Kenzo Muramoto, Tetsuo Kubota and Nobuyuki Miyasaka

J Immunol December 1, 2004, 173 (11) 7010-7016; DOI: https://doi.org/10.4049/jimmunol.173.11.7010
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CXC Chemokine Ligand 10 Neutralization Suppresses the Occurrence of Diabetes in Nonobese Diabetic Mice through Enhanced β Cell Proliferation without Affecting Insulitis
Jiro Morimoto, Hiroyuki Yoneyama, Akira Shimada, Toshikatsu Shigihara, Satoru Yamada, Yoichi Oikawa, Kouji Matsushima, Takao Saruta and Shosaku Narumi

J Immunol December 1, 2004, 173 (11) 7017-7024; DOI: https://doi.org/10.4049/jimmunol.173.11.7017
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Combinations of Anti-LFA-1, Everolimus, Anti-CD40 Ligand, and Allogeneic Bone Marrow Induce Central Transplantation Tolerance through Hemopoietic Chimerism, Including Protection from Chronic Heart Allograft Rejection
Barbara Metzler, Patrick Gfeller, Marc Bigaud, Jianping Li, Grazyna Wieczorek, Christoph Heusser, Philip Lake and Andreas Katopodis

J Immunol December 1, 2004, 173 (11) 7025-7036; DOI: https://doi.org/10.4049/jimmunol.173.11.7025
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Tracking of Proinflammatory Collagen-Specific T Cells in Early and Late Collagen-Induced Arthritis in Humanized Mice
Pia Svendsen, Claus B. Andersen, Nick Willcox, Anthony J. Coyle, Rikard Holmdahl, Thomas Kamradt and Lars Fugger

J Immunol December 1, 2004, 173 (11) 7037-7045; DOI: https://doi.org/10.4049/jimmunol.173.11.7037
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A Novel HLA-A*3303-Restricted Minor Histocompatibility Antigen Encoded by an Unconventional Open Reading Frame of Human TMSB4Y Gene
Hiroki Torikai, Yoshiki Akatsuka, Mikinori Miyazaki, Edus H. Warren, Taku Oba, Kunio Tsujimura, Kazuo Motoyoshi, Yasuo Morishima, Yoshihisa Kodera, Kiyotaka Kuzushima and Toshitada Takahashi

J Immunol December 1, 2004, 173 (11) 7046-7054; DOI: https://doi.org/10.4049/jimmunol.173.11.7046
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Anti-Phospholipid Antibodies Restore Mesenteric Ischemia/Reperfusion-Induced Injury in Complement Receptor 2/Complement Receptor 1-Deficient Mice
Sherry D. Fleming, Ryan P. Egan, Chunyan Chai, Guillermina Girardi, V. Michael Holers, Jane Salmon, Marc Monestier and George C. Tsokos

J Immunol December 1, 2004, 173 (11) 7055-7061; DOI: https://doi.org/10.4049/jimmunol.173.11.7055
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Self-Reactive T Cell Receptor-Reactive CD8⁺ T Cells Inhibit T Cell Lymphoma Growth In Vivo
Marie Gonthier, Régine Llobera, Jacques Arnaud and Bent Rubin

J Immunol December 1, 2004, 173 (11) 7062-7069; DOI: https://doi.org/10.4049/jimmunol.173.11.7062
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TLR4 Contributes to Disease-Inducing Mechanisms Resulting in Central Nervous System Autoimmune Disease
Steven M. Kerfoot, Elizabeth M. Long, Michael J. Hickey, Graciela Andonegui, Benoit M. Lapointe, Renata C. O. Zanardo, Claudine Bonder, Will G. James, Stephen M. Robbins and Paul Kubes

J Immunol December 1, 2004, 173 (11) 7070-7077; DOI: https://doi.org/10.4049/jimmunol.173.11.7070
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Intranasal HIV-1-gp160-DNA/gp41 Peptide Prime-Boost Immunization Regimen in Mice Results in Long-Term HIV-1 Neutralizing Humoral Mucosal and Systemic Immunity
Claudia Devito, Bartek Zuber, Ulf Schröder, Reinhold Benthin, Kenji Okuda, Kristina Broliden, Britta Wahren and Jorma Hinkula

J Immunol December 1, 2004, 173 (11) 7078-7089; DOI: https://doi.org/10.4049/jimmunol.173.11.7078

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PILLARS OF IMMUNOLOGY

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

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CLINICAL IMMUNOLOGY

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