The Journal of Immunology: 172 (7)

April 1, 2004; Volume 172,Issue 7

IN THIS ISSUE

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IN THIS ISSUE

J Immunol April 1, 2004, 172 (7) 3981-3982; DOI: https://doi.org/10.4049/jimmunol.172.7.3981

BRIEF REVIEWS

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IL-2, Regulatory T Cells, and Tolerance
Brad H. Nelson

J Immunol April 1, 2004, 172 (7) 3983-3988; DOI: https://doi.org/10.4049/jimmunol.172.7.3983

CUTTING EDGE

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Cutting Edge: Innate Immune System Discriminates between RNA Containing Bacterial versus Eukaryotic Structural Features That Prime for High-Level IL-12 Secretion by Dendritic Cells
Gary K. Koski, Katalin Karikó, Shuwen Xu, Drew Weissman, Peter A. Cohen and Brian J. Czerniecki

J Immunol April 1, 2004, 172 (7) 3989-3993; DOI: https://doi.org/10.4049/jimmunol.172.7.3989
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Cutting Edge: CD96 (Tactile) Promotes NK Cell-Target Cell Adhesion by Interacting with the Poliovirus Receptor (CD155)
Anja Fuchs, Marina Cella, Emanuele Giurisato, Andrey S. Shaw and Marco Colonna

J Immunol April 1, 2004, 172 (7) 3994-3998; DOI: https://doi.org/10.4049/jimmunol.172.7.3994

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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CCR7 Directs the Migration of Thymocytes into the Thymic Medulla
Joanne Kwan and Nigel Killeen

J Immunol April 1, 2004, 172 (7) 3999-4007; DOI: https://doi.org/10.4049/jimmunol.172.7.3999
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Siva-1 and an Alternative Splice Form Lacking the Death Domain, Siva-2, Similarly Induce Apoptosis in T Lymphocytes via a Caspase-Dependent Mitochondrial Pathway
Bénédicte Py, Christian Slomianny, Patrick Auberger, Patrice X. Petit and Serge Benichou

J Immunol April 1, 2004, 172 (7) 4008-4017; DOI: https://doi.org/10.4049/jimmunol.172.7.4008
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Antibody Targeting of the CC Chemokine Ligand 5 Results in Diminished Leukocyte Infiltration into the Central Nervous System and Reduced Neurologic Disease in a Viral Model of Multiple Sclerosis
William G. Glass, Michelle J. Hickey, Jenny L. Hardison, Michael T. Liu, Jerry E. Manning and Thomas E. Lane

J Immunol April 1, 2004, 172 (7) 4018-4025; DOI: https://doi.org/10.4049/jimmunol.172.7.4018
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Intralesional Injection of Adenovirus Encoding CC Chemokine Ligand 16 Inhibits Mammary Tumor Growth and Prevents Metastatic-Induced Death after Surgical Removal of the Treated Primary Tumor
Cristiana Guiducci, Emma Di Carlo, Mariella Parenza, Mary Hitt, Mirella Giovarelli, Piero Musiani and Mario P. Colombo

J Immunol April 1, 2004, 172 (7) 4026-4036; DOI: https://doi.org/10.4049/jimmunol.172.7.4026
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Establishment of Early Lymphoid Organ Infrastructure in Transplanted Tumors Mediated by Local Production of Lymphotoxin α and in the Combined Absence of Functional B and T Cells
Hye-Jung Kim, Thomas Kammertoens, Marko Janke, Oliver Schmetzer, Zhihai Qin, Claudia Berek and Thomas Blankenstein

J Immunol April 1, 2004, 172 (7) 4037-4047; DOI: https://doi.org/10.4049/jimmunol.172.7.4037
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Monomeric IgE Stimulates NFAT Translocation Into the Nucleus, a Rise in Cytosol Ca²⁺, Degranulation, and Membrane Ruffling in the Cultured Rat Basophilic Leukemia-2H3 Mast Cell Line
Vinita Pandey, Shoji Mihara, Amanda Fensome-Green, Stephen Bolsover and Shamshad Cockcroft

J Immunol April 1, 2004, 172 (7) 4048-4058; DOI: https://doi.org/10.4049/jimmunol.172.7.4048
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Proinflammatory Mediators and Genetic Background in Oncogene Mediated Tumor Progression
John P. Russell, Julie B. Engiles and Jay L. Rothstein

J Immunol April 1, 2004, 172 (7) 4059-4067; DOI: https://doi.org/10.4049/jimmunol.172.7.4059
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Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts
Jill E. Kolodsick, Galen B. Toews, Claudia Jakubzick, Cory Hogaboam, Thomas A. Moore, Andrew McKenzie, Carol A. Wilke, Cara J. Chrisman and Bethany B. Moore

J Immunol April 1, 2004, 172 (7) 4068-4076; DOI: https://doi.org/10.4049/jimmunol.172.7.4068
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Flt3 Ligand Preferentially Increases the Number of Functionally Active Myeloid Dendritic Cells in the Lungs of Mice
Barbara J. Masten, Gwyneth K. Olson, Donna F. Kusewitt and Mary F. Lipscomb

J Immunol April 1, 2004, 172 (7) 4077-4083; DOI: https://doi.org/10.4049/jimmunol.172.7.4077
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Mapping of Epitopes for Autoantibodies to the Type 1 Diabetes Autoantigen IA-2 by Peptide Phage Display and Molecular Modeling: Overlap of Antibody and T Cell Determinants
James A. Dromey, Sarah M. Weenink, Günther H. Peters, Josef Endl, Patrick J. Tighe, Ian Todd and Michael R. Christie

J Immunol April 1, 2004, 172 (7) 4084-4090; DOI: https://doi.org/10.4049/jimmunol.172.7.4084
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Src Homology 2 Domain-Containing Protein Tyrosine Phosphatase Substrate 1 Regulates the Migration of Langerhans Cells from the Epidermis to Draining Lymph Nodes
Atsushi Fukunaga, Hiroshi Nagai, Tetsuya Noguchi, Hideki Okazawa, Takashi Matozaki, Xijun Yu, Carl F. Lagenaur, Nakayuki Honma, Masamitsu Ichihashi, Masato Kasuga, Chikako Nishigori and Tatsuya Horikawa

J Immunol April 1, 2004, 172 (7) 4091-4099; DOI: https://doi.org/10.4049/jimmunol.172.7.4091
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Ligation of B7-1/B7-2 by Human CD4⁺ T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells
David H. Munn, Madhav D. Sharma and Andrew L. Mellor

J Immunol April 1, 2004, 172 (7) 4100-4110; DOI: https://doi.org/10.4049/jimmunol.172.7.4100
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Genome-Wide Analysis of Molecular Changes in IL-12-Induced Control of Mammary Carcinoma via IFN-γ-Independent Mechanisms
Xiaoyan Shi, Shanjin Cao, Maki Mitsuhashi, Zhaoying Xiang and Xiaojing Ma

J Immunol April 1, 2004, 172 (7) 4111-4122; DOI: https://doi.org/10.4049/jimmunol.172.7.4111
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CD4⁺CD25⁺ Regulatory T Cells Control the Severity of Viral Immunoinflammatory Lesions
Susmit Suvas, Ahmet Kursat Azkur, Bum Seok Kim, Uday Kumaraguru and Barry T. Rouse

J Immunol April 1, 2004, 172 (7) 4123-4132; DOI: https://doi.org/10.4049/jimmunol.172.7.4123
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Microarray Analysis of Lyn-Deficient B Cells Reveals Germinal Center-Associated Nuclear Protein and Other Genes Associated with the Lymphoid Germinal Center
Zeljka Korade Mirnics, Eva Caudell, YanHua Gao, Kazuhiko Kuwahara, Nobuo Sakaguchi, Tomohiro Kurosaki, Joan Burnside, Károly Mirnics and Seth J. Corey

J Immunol April 1, 2004, 172 (7) 4133-4141; DOI: https://doi.org/10.4049/jimmunol.172.7.4133
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Effect of Decreasing the Affinity of the Class II-Associated Invariant Chain Peptide on the MHC Class II Peptide Repertoire in the Presence or Absence of H-2M1
Karen Honey, Katherine Forbush, Peter E. Jensen and Alexander Y. Rudensky

J Immunol April 1, 2004, 172 (7) 4142-4150; DOI: https://doi.org/10.4049/jimmunol.172.7.4142
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Intestinal Intraepithelial Lymphocyte γδ-T Cell-Derived Keratinocyte Growth Factor Modulates Epithelial Growth in the Mouse
Hua Yang, Paul A. Antony, Barbara E. Wildhaber and Daniel H. Teitelbaum

J Immunol April 1, 2004, 172 (7) 4151-4158; DOI: https://doi.org/10.4049/jimmunol.172.7.4151
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Separation of the New Zealand Black Genetic Contribution to Lupus from New Zealand Black Determined Expansions of Marginal Zone B and B1a Cells
Stephanie Atencio, Hirofumi Amano, Shozo Izui and Brian L. Kotzin

J Immunol April 1, 2004, 172 (7) 4159-4166; DOI: https://doi.org/10.4049/jimmunol.172.7.4159
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Detection of Cell Surface Ligands for the γδ TCR Using Soluble TCRs
M. Kemal Aydintug, Christina L. Roark, Xiang Yin, J. M. Wands, Willi K. Born and Rebecca L. O’Brien

J Immunol April 1, 2004, 172 (7) 4167-4175; DOI: https://doi.org/10.4049/jimmunol.172.7.4167
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Virus-Induced Activation of Self-Specific TCRαβ CD8αα Intraepithelial Lymphocytes Does Not Abolish Their Self-Tolerance in the Intestine
Leslie Saurer, Inge Seibold, Silvia Rihs, Claudio Vallan, Tilman Dumrese and Christoph Mueller

J Immunol April 1, 2004, 172 (7) 4176-4183; DOI: https://doi.org/10.4049/jimmunol.172.7.4176
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CTLA-4⁺CD8⁺ T Cells That Encounter B7-2⁺ Iris Pigment Epithelial Cells Express Their Own B7-2 to Achieve Global Suppression of T Cell Activation
Sunao Sugita, Tat Fong Ng, Johannes Schwartzkopff and J. Wayne Streilein

J Immunol April 1, 2004, 172 (7) 4184-4194; DOI: https://doi.org/10.4049/jimmunol.172.7.4184
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Glucose-Regulated Protein 94/Glycoprotein 96 Elicits Bystander Activation of CD4⁺ T Cell Th1 Cytokine Production In Vivo
Julie C. Baker-LePain, Marcella Sarzotti and Christopher V. Nicchitta

J Immunol April 1, 2004, 172 (7) 4195-4203; DOI: https://doi.org/10.4049/jimmunol.172.7.4195
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Maintenance, Loss, and Resurgence of T Cell Responses During Acute, Protracted, and Chronic Viral Infections
Michael J. Fuller, Aaruni Khanolkar, Anne E. Tebo and Allan J. Zajac

J Immunol April 1, 2004, 172 (7) 4204-4214; DOI: https://doi.org/10.4049/jimmunol.172.7.4204
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CD4-Directed Peptide Vaccination Augments an Antitumor Response, but Efficacy Is Limited by the Number of CD8⁺ T Cell Precursors
Holly L. Hanson, Silvia S. Kang, Lyse A. Norian, Ken Matsui, Leigh A. O’Mara and Paul M. Allen

J Immunol April 1, 2004, 172 (7) 4215-4224; DOI: https://doi.org/10.4049/jimmunol.172.7.4215
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Monocyte Surface-Bound IL-15 Can Function as an Activating Receptor and Participate in Reverse Signaling
Graham G. Neely, Slava Epelman, Ling Ling Ma, Pina Colarusso, Christopher J. Howlett, Ernest K. Amankwah, Amanda C. McIntyre, Stephen M. Robbins and Christopher H. Mody

J Immunol April 1, 2004, 172 (7) 4225-4234; DOI: https://doi.org/10.4049/jimmunol.172.7.4225
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Thymocytes between the β-Selection and Positive Selection Checkpoints Are Nonresponsive to IL-7 as Assessed by STAT-5 Phosphorylation
C. Justin Van De Wiele, Julie H. Marino, Bryce W. Murray, Stephen S. Vo, Michael E. Whetsell and T. Kent Teague

J Immunol April 1, 2004, 172 (7) 4235-4244; DOI: https://doi.org/10.4049/jimmunol.172.7.4235
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IFN-γ Stimulates the Expression of a Novel Secretoglobin That Regulates Chemotactic Cell Migration and Invasion
Moonsuk S. Choi, Rabindranath Ray, Zhongjian Zhang and Anil B. Mukherjee

J Immunol April 1, 2004, 172 (7) 4245-4252; DOI: https://doi.org/10.4049/jimmunol.172.7.4245
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Plasmacytoid Dendritic Cells Regulate Th Cell Responses through OX40 Ligand and Type I IFNs
Tomoki Ito, Ryuichi Amakawa, Muneo Inaba, Toshiyuki Hori, Maiko Ota, Kengo Nakamura, Masashi Takebayashi, Michihiko Miyaji, Tomoo Yoshimura, Kayo Inaba and Shirou Fukuhara

J Immunol April 1, 2004, 172 (7) 4253-4259; DOI: https://doi.org/10.4049/jimmunol.172.7.4253
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Defining Th1 and Th2 Immune Responses in a Reciprocal Cytokine Environment In Vivo
Tanuja Chitnis, Alan D. Salama, Michael J. Grusby, Mohamed H. Sayegh and Samia J. Khoury

J Immunol April 1, 2004, 172 (7) 4260-4265; DOI: https://doi.org/10.4049/jimmunol.172.7.4260
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Enrichment of Lck in Lipid Rafts Regulates Colocalized Fyn Activation and the Initiation of Proximal Signals through TCRαβ
Dominik Filipp, Bernadine L. Leung, Jenny Zhang, André Veillette and Michael Julius

J Immunol April 1, 2004, 172 (7) 4266-4274; DOI: https://doi.org/10.4049/jimmunol.172.7.4266
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Smad3 Is Essential for TGF-β1 to Suppress IL-2 Production and TCR-Induced Proliferation, but Not IL-2-Induced Proliferation
Susan C. McKarns, Ronald H. Schwartz and Norbert E. Kaminski

J Immunol April 1, 2004, 172 (7) 4275-4284; DOI: https://doi.org/10.4049/jimmunol.172.7.4275
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Immune Regulation by Self-Reactive T Cells is Antigen Specific
Corinne Tanchot, Florence Vasseur, Christiane Pontoux, Corinne Garcia and Adelaida Sarukhan

J Immunol April 1, 2004, 172 (7) 4285-4291; DOI: https://doi.org/10.4049/jimmunol.172.7.4285
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TNF Receptor-Associated Factor 5 Limits the Induction of Th2 Immune Responses
Takanori So, Shahram Salek-Ardakani, Hiroyasu Nakano, Carl F. Ware and Michael Croft

J Immunol April 1, 2004, 172 (7) 4292-4297; DOI: https://doi.org/10.4049/jimmunol.172.7.4292
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Lupus IgG V_H4.34 Antibodies Bind to a 220-kDa Glycoform of CD45/B220 on the Surface of Human B Lymphocytes
Amedeo J. Cappione, Aimee E. Pugh-Bernard, Jennifer H. Anolik and Iñaki Sanz

J Immunol April 1, 2004, 172 (7) 4298-4307; DOI: https://doi.org/10.4049/jimmunol.172.7.4298
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Recombinogenic Phenotype of Human Activation-Induced Cytosine Deaminase
Vladimir P. Poltoratsky, Samuel H. Wilson, Thomas A. Kunkel and Youri I. Pavlov

J Immunol April 1, 2004, 172 (7) 4308-4313; DOI: https://doi.org/10.4049/jimmunol.172.7.4308

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Identifiying Human MHC Supertypes Using Bioinformatic Methods
Irini A. Doytchinova, Pingping Guan and Darren R. Flower

J Immunol April 1, 2004, 172 (7) 4314-4323; DOI: https://doi.org/10.4049/jimmunol.172.7.4314
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Depletion of Cellular Cholesterol and Lipid Rafts Increases Shedding of CD30
Bastian von Tresckow, Karl-Josef Kallen, Elke Pogge von Strandmann, Peter Borchmann, Hans Lange, Andreas Engert and Hinrich P. Hansen

J Immunol April 1, 2004, 172 (7) 4324-4331; DOI: https://doi.org/10.4049/jimmunol.172.7.4324
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TNF and Phorbol Esters Induce Lymphotoxin-β Expression through Distinct Pathways Involving Ets and NF-κB Family Members
Dominic C. Voon, Lily S. Subrata, Mahdad Karimi, Daniela Ulgiati and Lawrence J. Abraham

J Immunol April 1, 2004, 172 (7) 4332-4341; DOI: https://doi.org/10.4049/jimmunol.172.7.4332
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Characterization of Recombinant Mannan-Binding Lectin-Associated Serine Protease (MASP)-3 Suggests an Activation Mechanism Different from That of MASP-1 and MASP-2
Stéphanie Zundel, Sandor Cseh, Monique Lacroix, Mads R. Dahl, Misao Matsushita, Jean-Pierre Andrieu, Wilhelm J. Schwaeble, Jens C. Jensenius, Teizo Fujita, Gérard J. Arlaud and Nicole M. Thielens

J Immunol April 1, 2004, 172 (7) 4342-4350; DOI: https://doi.org/10.4049/jimmunol.172.7.4342
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Mutational Analyses of the Recombinant Globular Regions of Human C1q A, B, and C Chains Suggest an Essential Role for Arginine and Histidine Residues in the C1q-IgG Interaction
Mihaela S. Kojouharova, Mihaela G. Gadjeva, Ivanka G. Tsacheva, Aleksandra Zlatarova, Liubka T. Roumenina, Magdalena I. Tchorbadjieva, Boris P. Atanasov, Patrick Waters, Britta C. Urban, Robert B. Sim, Kenneth B. M. Reid and Uday Kishore

J Immunol April 1, 2004, 172 (7) 4351-4358; DOI: https://doi.org/10.4049/jimmunol.172.7.4351
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Localization of the Domains in Runx Transcription Factors Required for the Repression of CD4 in Thymocytes
Janice C. Telfer, Emmett E. Hedblom, Michele K. Anderson, Micheline N. Laurent and Ellen V. Rothenberg

J Immunol April 1, 2004, 172 (7) 4359-4370; DOI: https://doi.org/10.4049/jimmunol.172.7.4359
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Identification and Molecular Cloning of Functional Chicken IL-12
Winfried G. J. Degen, Nancy van Daal, Hanneke I. van Zuilekom, Joan Burnside and Virgil E. J. C. Schijns

J Immunol April 1, 2004, 172 (7) 4371-4380; DOI: https://doi.org/10.4049/jimmunol.172.7.4371
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Cloning, Expression, Cellular Distribution, and Role in Chemotaxis of a C5a Receptor in Rainbow Trout: The First Identification of a C5a Receptor in a Nonmammalian Species
Hani Boshra, Jun Li, Rodney Peters, John Hansen, Anjan Matlapudi and J. Oriol Sunyer

J Immunol April 1, 2004, 172 (7) 4381-4390; DOI: https://doi.org/10.4049/jimmunol.172.7.4381

HOST DEFENSE

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Signaling through Toll-Like Receptors Triggers HIV-1 Replication in Latently Infected Mast Cells
J. Bruce Sundstrom, Dawn M. Little, Francois Villinger, Jane E. Ellis and Aftab A. Ansari

J Immunol April 1, 2004, 172 (7) 4391-4401; DOI: https://doi.org/10.4049/jimmunol.172.7.4391
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Induction of a Rapid and Strong Antigen-Specific Intraepithelial Lymphocyte Response during Oral Encephalitozoon cuniculi Infection
Magali Moretto, Louis M. Weiss and Imtiaz A. Khan

J Immunol April 1, 2004, 172 (7) 4402-4409; DOI: https://doi.org/10.4049/jimmunol.172.7.4402
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Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response
Cord Sunderkötter, Tatjana Nikolic, Marilyn J. Dillon, Nico van Rooijen, Martin Stehling, Douglas A. Drevets and Pieter J. M. Leenen

J Immunol April 1, 2004, 172 (7) 4410-4417; DOI: https://doi.org/10.4049/jimmunol.172.7.4410
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The Ly-6C^high Monocyte Subpopulation Transports Listeria monocytogenes into the Brain during Systemic Infection of Mice
Douglas A. Drevets, Marilyn J. Dillon, Jennifer S. Schawang, Nico van Rooijen, Jan Ehrchen, Cord Sunderkötter and Pieter J. M. Leenen

J Immunol April 1, 2004, 172 (7) 4418-4424; DOI: https://doi.org/10.4049/jimmunol.172.7.4418
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Toll-Like Receptor 2 (TLR2)-Dependent-Positive and TLR2-Independent-Negative Regulation of Proinflammatory Cytokines by Mycobacterial Lipomannans
Valerie J. Quesniaux, Delphine M. Nicolle, David Torres, Laurent Kremer, Yann Guérardel, Jérôme Nigou, Germain Puzo, François Erard and Bernhard Ryffel

J Immunol April 1, 2004, 172 (7) 4425-4434; DOI: https://doi.org/10.4049/jimmunol.172.7.4425
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Preferential HLA Usage in the Influenza Virus-Specific CTL Response
Adrianus C. M. Boon, Gerrie de Mutsert, Ron A. M. Fouchier, Kees Sintnicolaas, Albert D. M. E. Osterhaus and Guus F. Rimmelzwaan

J Immunol April 1, 2004, 172 (7) 4435-4443; DOI: https://doi.org/10.4049/jimmunol.172.7.4435
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HIV-Specific CD8⁺ T Cells Exhibit Markedly Reduced Levels of Bcl-2 and Bcl-x_L
Constantinos Petrovas, Yvonne M. Mueller, Ioannis D. Dimitriou, Paul M. Bojczuk, Karam C. Mounzer, James Witek, John D. Altman and Peter D. Katsikis

J Immunol April 1, 2004, 172 (7) 4444-4453; DOI: https://doi.org/10.4049/jimmunol.172.7.4444
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Macrophage Interactions with Neutrophils Regulate Leishmania major Infection
Flávia L. Ribeiro-Gomes, Ana C. Otero, Nitza A. Gomes, Maria Carolina A. Moniz-de-Souza, Lea Cysne-Finkelstein, Andrea C. Arnholdt, Vera L. Calich, Sergio G. Coutinho, Marcela F. Lopes and George A. DosReis

J Immunol April 1, 2004, 172 (7) 4454-4462; DOI: https://doi.org/10.4049/jimmunol.172.7.4454
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Toll-Like Receptors Are Temporally Involved in Host Defense
David S. Weiss, Bärbel Raupach, Kiyoshi Takeda, Shizuo Akira and Arturo Zychlinsky

J Immunol April 1, 2004, 172 (7) 4463-4469; DOI: https://doi.org/10.4049/jimmunol.172.7.4463

INFLAMMATION

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CD14 Is an Acute-Phase Protein
Sylvette Bas, Benoit R. Gauthier, Ursula Spenato, Sybille Stingelin and Cem Gabay

J Immunol April 1, 2004, 172 (7) 4470-4479; DOI: https://doi.org/10.4049/jimmunol.172.7.4470
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Lysophosphatidic Acid Induces Chemotaxis, Oxygen Radical Production, CD11b Up-Regulation, Ca²⁺ Mobilization, and Actin Reorganization in Human Eosinophils via Pertussis Toxin-Sensitive G Proteins
Marco Idzko, Martin Laut, Elisabeth Panther, Stephan Sorichter, Thorsten Dürk, Joachim W. Fluhr, Yared Herouy, Maja Mockenhaupt, Daniel Myrtek, Peter Elsner and Johannes Norgauer

J Immunol April 1, 2004, 172 (7) 4480-4485; DOI: https://doi.org/10.4049/jimmunol.172.7.4480
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O-Methylated Catechins from Tea Leaves Inhibit Multiple Protein Kinases in Mast Cells
Mari Maeda-Yamamoto, Naoki Inagaki, Jiro Kitaura, Takao Chikumoto, Hiroharu Kawahara, Yuko Kawakami, Mitsuaki Sano, Toshio Miyase, Hirofumi Tachibana, Hiroichi Nagai and Toshiaki Kawakami

J Immunol April 1, 2004, 172 (7) 4486-4492; DOI: https://doi.org/10.4049/jimmunol.172.7.4486
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Neutrophil Elastase (NE)-Deficient Mice Demonstrate a Nonredundant Role for NE in Neutrophil Migration, Generation of Proinflammatory Mediators, and Phagocytosis in Response to Zymosan Particles In Vivo
Rebecca E. Young, Richard D. Thompson, Karen Y. Larbi, Mylinh La, Clare E. Roberts, Steven D. Shapiro, Mauro Perretti and Sussan Nourshargh

J Immunol April 1, 2004, 172 (7) 4493-4502; DOI: https://doi.org/10.4049/jimmunol.172.7.4493
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Immunization with Glucose-6-Phosphate Isomerase Induces T Cell-Dependent Peripheral Polyarthritis in Genetically Unaltered Mice
David Schubert, Bert Maier, Lars Morawietz, Veit Krenn and Thomas Kamradt

J Immunol April 1, 2004, 172 (7) 4503-4509; DOI: https://doi.org/10.4049/jimmunol.172.7.4503
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Deletion of the Mouse Meprin β Metalloprotease Gene Diminishes the Ability of Leukocytes to Disseminate through Extracellular Matrix
Jacqueline M. Crisman, Binzhi Zhang, Lourdes P. Norman and Judith S. Bond

J Immunol April 1, 2004, 172 (7) 4510-4519; DOI: https://doi.org/10.4049/jimmunol.172.7.4510
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Aerobic Exercise Attenuates Airway Inflammatory Responses in a Mouse Model of Atopic Asthma
Amy Pastva, Kim Estell, Trenton R. Schoeb, T. Prescott Atkinson and Lisa M. Schwiebert

J Immunol April 1, 2004, 172 (7) 4520-4526; DOI: https://doi.org/10.4049/jimmunol.172.7.4520
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IL-4-Dependent Th2 Collateral Priming to Inhaled Antigens Independent of Toll-Like Receptor 4 and Myeloid Differentiation Factor 88
Stephanie C. Eisenbarth, Alex Zhadkevich, Patricia Ranney, Christina A. Herrick and Kim Bottomly

J Immunol April 1, 2004, 172 (7) 4527-4534; DOI: https://doi.org/10.4049/jimmunol.172.7.4527
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Adenoviral Gene Delivery of Elafin and Secretory Leukocyte Protease Inhibitor Attenuates NF-κB-Dependent Inflammatory Responses of Human Endothelial Cells and Macrophages to Atherogenic Stimuli
Peter A. Henriksen, Mary Hitt, Zhou Xing, Jun Wang, Chris Haslett, Rudolph A. Riemersma, David J. Webb, Yuri V. Kotelevtsev and Jean-Michel Sallenave

J Immunol April 1, 2004, 172 (7) 4535-4544; DOI: https://doi.org/10.4049/jimmunol.172.7.4535
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Complex Role of the IL-4 Receptor α in a Murine Model of Airway Inflammation: Expression of the IL-4 Receptor α on Nonlymphoid Cells of Bone Marrow Origin Contributes to Severity of Inflammation
Ann E. Kelly-Welch, Marco E. F. Melo, Elizabeth Smith, Andrew Q. Ford, Christian Haudenschild, Nancy Noben-Trauth and Achsah D. Keegan

J Immunol April 1, 2004, 172 (7) 4545-4555; DOI: https://doi.org/10.4049/jimmunol.172.7.4545

CLINICAL IMMUNOLOGY

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Monomeric Recombinant TCR Ligand Reduces Relapse Rate and Severity of Experimental Autoimmune Encephalomyelitis in SJL/J Mice through Cytokine Switch
Jianya Huan, Sandhya Subramanian, Richard Jones, Cathleen Rich, Jason Link, Jeff Mooney, Dennis N. Bourdette, Arthur A. Vandenbark, Gregory G. Burrows and Halina Offner

J Immunol April 1, 2004, 172 (7) 4556-4566; DOI: https://doi.org/10.4049/jimmunol.172.7.4556
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A Self T Cell Epitope Induces Autoantibody Response: Mechanism for Production of Antibodies to Diverse Glomerular Basement Membrane Antigens
Jean Wu, Jon Arends, Jason Borillo, Cindy Zhou, Justin Merszei, John McMahon and Ya-Huan Lou

J Immunol April 1, 2004, 172 (7) 4567-4574; DOI: https://doi.org/10.4049/jimmunol.172.7.4567
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Multiepitope Trojan Antigen Peptide Vaccines for the Induction of Antitumor CTL and Th Immune Responses
Jun Lu, Yuichiro Higashimoto, Ettore Appella and Esteban Celis

J Immunol April 1, 2004, 172 (7) 4575-4582; DOI: https://doi.org/10.4049/jimmunol.172.7.4575
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Pregnancy-Specific Down-Regulation of NF-κB Expression in T Cells in Humans Is Essential for the Maintenance of the Cytokine Profile Required for Pregnancy Success
Sharon A. McCracken, Eileen Gallery and Jonathan M. Morris

J Immunol April 1, 2004, 172 (7) 4583-4591; DOI: https://doi.org/10.4049/jimmunol.172.7.4583
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Mycobacterium tuberculosis Resides in Nonacidified Vacuoles in Endocytically Competent Alveolar Macrophages from Patients with Tuberculosis and HIV Infection
Henry C. Mwandumba, David G. Russell, Mukanthu H. Nyirenda, Jennifer Anderson, Sarah A. White, Malcolm E. Molyneux and S. Bertel Squire

J Immunol April 1, 2004, 172 (7) 4592-4598; DOI: https://doi.org/10.4049/jimmunol.172.7.4592
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Treatment of Melanoma with 5-Fluorouracil or Dacarbazine In Vitro Sensitizes Cells to Antigen-Specific CTL Lysis through Perforin/Granzyme- and Fas-Mediated Pathways
Sixun Yang and Frank G. Haluska

J Immunol April 1, 2004, 172 (7) 4599-4608; DOI: https://doi.org/10.4049/jimmunol.172.7.4599
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New Loci from New Zealand Black and New Zealand White on Chromosomes 4 and 12 Contribute to Lupus-Like Disease in the Context of BALB/c
Robert J. Rigby, Stephen J. Rozzo, Joseph J. Boyle, Margarita Lewis, Brian L. Kotzin and Timothy J. Vyse

J Immunol April 1, 2004, 172 (7) 4609-4617; DOI: https://doi.org/10.4049/jimmunol.172.7.4609
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Angiogenesis-Inflammation Cross-Talk: Vascular Endothelial Growth Factor Is Secreted by Activated T Cells and Induces Th1 Polarization
Felix Mor, Francisco J. Quintana and Irun R. Cohen

J Immunol April 1, 2004, 172 (7) 4618-4623; DOI: https://doi.org/10.4049/jimmunol.172.7.4618
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Terminal Deoxynucleotidyltransferase Deficiency Decreases Autoimmune Disease in Diabetes-Prone Nonobese Diabetic Mice and Lupus-Prone MRL-Fas^lpr Mice
Ian F. Robey, Melissa Peterson, Marc S. Horwitz, Dwight H. Kono, Thomas Stratmann, Argyrios N. Theofilopoulos, Nora Sarvetnick, Luc Teyton and Ann J. Feeney

J Immunol April 1, 2004, 172 (7) 4624-4629; DOI: https://doi.org/10.4049/jimmunol.172.7.4624
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Recruitment of STAT3 for Production of IL-10 by Colon Carcinoma Cells Induced by Macrophage-Derived IL-6
Jean-Philippe Herbeuval, Eric Lelievre, Claude Lambert, Michel Dy and Christian Genin

J Immunol April 1, 2004, 172 (7) 4630-4636; DOI: https://doi.org/10.4049/jimmunol.172.7.4630
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Human Rhinovirus Infection Induces Airway Epithelial Cell Production of Human β-Defensin 2 Both In Vitro and In Vivo
David Proud, Scherer P. Sanders and Shahina Wiehler

J Immunol April 1, 2004, 172 (7) 4637-4645; DOI: https://doi.org/10.4049/jimmunol.172.7.4637

CORRECTIONS

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CORRECTIONS

J Immunol April 1, 2004, 172 (7) 4646; DOI: https://doi.org/10.4049/jimmunol.172.7.4646
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CORRECTIONS

J Immunol April 1, 2004, 172 (7) 4646; DOI: https://doi.org/10.4049/jimmunol.172.7.4646-a
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CORRECTIONS

J Immunol April 1, 2004, 172 (7) 4647; DOI: https://doi.org/10.4049/jimmunol.172.7.4647

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IN THIS ISSUE

BRIEF REVIEWS

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

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