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Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells

Fabrice André, Nathalie Chaput, Nöel E. C. Schartz, Caroline Flament, Nathalie Aubert, Jacky Bernard, François Lemonnier, Graça Raposo, Bernard Escudier, Di-Hwei Hsu, Thomas Tursz, Sebastian Amigorena, Eric Angevin and Laurence Zitvogel
J Immunol February 15, 2004, 172 (4) 2126-2136; DOI: https://doi.org/10.4049/jimmunol.172.4.2126
Fabrice André
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Nathalie Chaput
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Nöel E. C. Schartz
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
¶Service de Dermatologie 2, AP-HP Saint Louis, Paris, France;
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Caroline Flament
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Nathalie Aubert
‡Centre Jean Godinot, Reims, France;
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Jacky Bernard
‡Centre Jean Godinot, Reims, France;
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François Lemonnier
§Unité d’Immunologie Cellulaire Antivirale, Institut Pasteur, Paris, France;
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Graça Raposo
†Unité Mixte de Recherche 144 Centre National de la Recherche Scientifique Institut Curie, Paris, France;
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Bernard Escudier
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Di-Hwei Hsu
#Anosys, Inc., Menlo Park, CA 94025.
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Thomas Tursz
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Sebastian Amigorena
∥Institut National de la Santé et de la Recherche Médicale Unité 520, Institut Curie, Paris, France; and
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Eric Angevin
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Laurence Zitvogel
*Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
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Article Information

vol. 172 no. 4 2126-2136
DOI 
https://doi.org/10.4049/jimmunol.172.4.2126
PubMed 
14764678

Published By 
The American Association of Immunologists, Inc.
Print ISSN 
0022-1767
Online ISSN 
1550-6606
History 
  • Received May 9, 2003
  • Accepted November 25, 2003
  • Published online February 5, 2004.

Copyright & Usage 
Copyright © 2004 by The American Association of Immunologists

Author Information

  1. Fabrice André2,*,
  2. Nathalie Chaput2,*,
  3. Nöel E. C. Schartz*,¶,
  4. Caroline Flament*,
  5. Nathalie Aubert‡,
  6. Jacky Bernard‡,
  7. François Lemonnier§,
  8. Graça Raposo†,
  9. Bernard Escudier*,
  10. Di-Hwei Hsu#,
  11. Thomas Tursz*,
  12. Sebastian Amigorena∥,
  13. Eric Angevin2,* and
  14. Laurence Zitvogel2,3,*
  1. *Unité d’Immunologie, ERM0208 Institut National de la Santé et de la Recherche Médicale, Department of Clinical Biology, Institut Gustave Roussy, Villejuif, France;
  2. †Unité Mixte de Recherche 144 Centre National de la Recherche Scientifique Institut Curie, Paris, France;
  3. ‡Centre Jean Godinot, Reims, France;
  4. §Unité d’Immunologie Cellulaire Antivirale, Institut Pasteur, Paris, France;
  5. ¶Service de Dermatologie 2, AP-HP Saint Louis, Paris, France;
  6. ∥Institut National de la Santé et de la Recherche Médicale Unité 520, Institut Curie, Paris, France; and
  7. #Anosys, Inc., Menlo Park, CA 94025.
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Article usage

Article usage: January 2004 to March 2021

AbstractFullPdf
Jan 2004001
Feb 2004261253464
Mar 200433172138
Apr 20042310670
May 2004218558
Jun 2004217056
Jul 2004158359
Aug 2004167752
Sep 2004127341
Oct 2004166534
Nov 2004275637
Dec 2004237229
Total 200446811121039
Jan 2005296128
Feb 2005125437
Mar 2005137963
Apr 200575745
May 200526652
Jun 200565247
Jul 200555141
Aug 200574729
Sep 200555243
Oct 200575437
Nov 200586645
Dec 200584325
Total 2005109682492
Jan 200625032
Feb 200664725
Mar 200673736
Apr 200603526
May 2006173723
Jun 200632116
Jul 200633215
Aug 200643028
Sep 200653738
Oct 200623225
Nov 200683121
Dec 200621410
Total 200659403295
Jan 200773422
Feb 200723120
Mar 200783325
Apr 200733623
May 200743226
Jun 200782926
Jul 2007123712
Aug 200753122
Sep 200793820
Oct 200752922
Nov 200783838
Dec 2007364820
Total 2007107416276
Jan 2008182323
Feb 2008112712
Mar 2008151627
Apr 2008232732
May 2008192225
Jun 200893217
Jul 2008162622
Aug 2008211715
Sep 2008552918
Oct 200860259
Nov 2008111821
Dec 200871718
Total 2008265279239
Jan 2009141914
Feb 2009153429
Mar 2009272732
Apr 2009171912
May 2009102616
Jun 200991717
Jul 2009122224
Aug 200951213
Sep 20097127
Oct 2009352021
Nov 2009272023
Dec 2009361822
Total 2009214246230
Jan 2010102219
Feb 201072017
Mar 201072721
Apr 201082221
May 2010113522
Jun 201072612
Jul 2010102718
Aug 201091924
Sep 2010331720
Oct 2010111713
Nov 2010162414
Dec 2010123225
Total 2010141288226
Jan 201192218
Feb 201172415
Mar 2011182517
Apr 201182921
May 201193327
Jun 2011163925
Jul 201191633
Aug 2011171415
Sep 2011161513
Oct 2011222731
Nov 2011222321
Dec 2011142520
Total 2011167292256
Jan 2012132716
Feb 2012154033
Mar 2012144025
Apr 2012163120
May 2012192417
Jun 2012113320
Jul 2012193220
Aug 2012161818
Sep 2012121711
Oct 2012112922
Nov 2012222836
Dec 201291821
Total 2012177337259
Jan 2013141919
Feb 2013112217
Mar 2013113230
Apr 2013131140
May 2013212027
Jun 2013172326
Jul 201361819
Aug 201391410
Sep 2013112020
Oct 2013132219
Nov 2013202319
Dec 2013291317
Total 2013175237263
Jan 2014213131
Feb 2014121319
Mar 2014233937
Apr 2014192616
May 2014352125
Jun 2014261829
Jul 2014413726
Aug 2014102321
Sep 2014292537
Oct 2014192329
Nov 2014272227
Dec 201486548
Total 2014270343345
Jan 2015231734
Feb 2015204828
Mar 2015232356
Apr 2015161830
May 2015213236
Jun 2015141825
Jul 2015181929
Aug 2015162340
Sep 2015362628
Oct 2015152224
Nov 2015212734
Dec 2015172539
Total 2015240298403
Jan 2016264144
Feb 2016135042
Mar 201672828
Apr 2016103329
May 201693026
Jun 2016204129
Jul 201683233
Aug 2016112221
Sep 2016151716
Oct 201683327
Nov 2016192124
Dec 201671020
Total 2016153358339
Jan 201742718
Feb 201782219
Mar 2017142620
Apr 201762111
May 201794315
Jun 2017133125
Jul 201783416
Aug 201764129
Sep 2017125140
Oct 2017114025
Nov 2017135828
Dec 2017114319
Total 2017115437265
Jan 2018116439
Feb 201884422
Mar 201863017
Apr 2018103350
May 2018115841
Jun 201893932
Jul 201892719
Aug 201872124
Sep 2018156134
Oct 2018126846
Nov 2018105031
Dec 2018104331
Total 2018118538386
Jan 201954923
Feb 2019184236
Mar 201974144
Apr 201983137
May 201963219
Jun 2019174134
Jul 2019123631
Aug 20191211821
Sep 201976121
Oct 2019118925
Nov 2019132823
Dec 201953824
Total 2019121606338
Jan 2020104428
Feb 2020102921
Mar 202094123
Apr 202075726
May 2020124222
Jun 2020112218
Jul 202072113
Aug 202075330
Sep 202084626
Oct 2020145328
Nov 202083622
Dec 2020154830
Total 2020118492287
Jan 2021114226
Feb 202175029
Mar 2021123629
Total 20213012884
Total304774926022

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The Journal of Immunology: 172 (4)
The Journal of Immunology
Vol. 172, Issue 4
15 Feb 2004
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Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells
Fabrice André, Nathalie Chaput, Nöel E. C. Schartz, Caroline Flament, Nathalie Aubert, Jacky Bernard, François Lemonnier, Graça Raposo, Bernard Escudier, Di-Hwei Hsu, Thomas Tursz, Sebastian Amigorena, Eric Angevin, Laurence Zitvogel
The Journal of Immunology February 15, 2004, 172 (4) 2126-2136; DOI: 10.4049/jimmunol.172.4.2126

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Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells
Fabrice André, Nathalie Chaput, Nöel E. C. Schartz, Caroline Flament, Nathalie Aubert, Jacky Bernard, François Lemonnier, Graça Raposo, Bernard Escudier, Di-Hwei Hsu, Thomas Tursz, Sebastian Amigorena, Eric Angevin, Laurence Zitvogel
The Journal of Immunology February 15, 2004, 172 (4) 2126-2136; DOI: 10.4049/jimmunol.172.4.2126
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