The Journal of Immunology: 172 (4)

February 15, 2004; Volume 172,Issue 4

IN THIS ISSUE

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IN THIS ISSUE

J Immunol February 15, 2004, 172 (4) 1989-1990; DOI: https://doi.org/10.4049/jimmunol.172.4.1989

CUTTING EDGE

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Cutting Edge: In Vitro-Generated Tolerogenic APC Induce CD8⁺ T Regulatory Cells That Can Suppress Ongoing Experimental Autoimmune Encephalomyelitis
Douglas E. Faunce, Ania Terajewicz and Joan Stein-Streilein

J Immunol February 15, 2004, 172 (4) 1991-1995; DOI: https://doi.org/10.4049/jimmunol.172.4.1991
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Cutting Edge: Conventional CD8α⁺ Dendritic Cells Are Generally Involved in Priming CTL Immunity to Viruses
Gabrielle T. Belz, Christopher M. Smith, Daniel Eichner, Ken Shortman, Guna Karupiah, Francis R. Carbone and William R. Heath

J Immunol February 15, 2004, 172 (4) 1996-2000; DOI: https://doi.org/10.4049/jimmunol.172.4.1996
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Cutting Edge: Toll-Like Receptor Signaling in Macrophages Induces Ligands for the NKG2D Receptor
Jessica A. Hamerman, Kouetsu Ogasawara and Lewis L. Lanier

J Immunol February 15, 2004, 172 (4) 2001-2005; DOI: https://doi.org/10.4049/jimmunol.172.4.2001
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Cutting Edge: IL-26 Signals through a Novel Receptor Complex Composed of IL-20 Receptor 1 and IL-10 Receptor 2
Faruk Sheikh, Vitaliy V. Baurin, Anita Lewis-Antes, Nital K. Shah, Sergey V. Smirnov, Shubha Anantha, Harold Dickensheets, Laure Dumoutier, Jean-Christophe Renauld, Alexander Zdanov, Raymond P. Donnelly and Sergei V. Kotenko

J Immunol February 15, 2004, 172 (4) 2006-2010; DOI: https://doi.org/10.4049/jimmunol.172.4.2006
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Cutting Edge: T Cells Trigger CD40-Dependent Platelet Activation and Granular RANTES Release: A Novel Pathway for Immune Response Amplification
Silvio Danese, Carol de la Motte, Brenda M. Rivera Reyes, Miquel Sans, Alan D. Levine and Claudio Fiocchi

J Immunol February 15, 2004, 172 (4) 2011-2015; DOI: https://doi.org/10.4049/jimmunol.172.4.2011
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Cutting Edge: Dendritic Cells Copulsed with Microbial and Helminth Antigens Undergo Modified Maturation, Segregate the Antigens to Distinct Intracellular Compartments, and Concurrently Induce Microbe-Specific Th1 and Helminth-Specific Th2 Responses
Laura Cervi, Andrew S. MacDonald, Colleen Kane, Florence Dzierszinski and Edward J. Pearce

J Immunol February 15, 2004, 172 (4) 2016-2020; DOI: https://doi.org/10.4049/jimmunol.172.4.2016

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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Visualizing the Site and Dynamics of IgG Salvage by the MHC Class I-Related Receptor, FcRn
Raimund J. Ober, Cruz Martinez, Carlos Vaccaro, Jinchun Zhou and E. Sally Ward

J Immunol February 15, 2004, 172 (4) 2021-2029; DOI: https://doi.org/10.4049/jimmunol.172.4.2021
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Visualization of Antigen Presentation by Actin-Mediated Targeting of Glycolipid-Enriched Membrane Domains to the Immune Synapse of B Cell APCs
Claire Gordy, Sudha Mishra and William Rodgers

J Immunol February 15, 2004, 172 (4) 2030-2038; DOI: https://doi.org/10.4049/jimmunol.172.4.2030
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Inhibitory Effect of Toll-Like Receptor 4 on Fusion between Phagosomes and Endosomes/Lysosomes in Macrophages
Akiko Shiratsuchi, Ikuko Watanabe, Osamu Takeuchi, Shizuo Akira and Yoshinobu Nakanishi

J Immunol February 15, 2004, 172 (4) 2039-2047; DOI: https://doi.org/10.4049/jimmunol.172.4.2039
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IL-21 Induces the Functional Maturation of Murine NK Cells
Jason Brady, Yoshihiro Hayakawa, Mark J. Smyth and Stephen L. Nutt

J Immunol February 15, 2004, 172 (4) 2048-2058; DOI: https://doi.org/10.4049/jimmunol.172.4.2048
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IL-4 Induces Differentiation and Expansion of Th2 Cytokine-Producing Eosinophils
Luqiu Chen, Kristy A. Grabowski, Jun-ping Xin, John Coleman, Zan Huang, Baltazar Espiritu, Serhan Alkan, H. Bill Xie, Yuechun Zhu, Fletcher A. White, John Clancy Jr and Hua Huang

J Immunol February 15, 2004, 172 (4) 2059-2066; DOI: https://doi.org/10.4049/jimmunol.172.4.2059
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NF-κB-Inducing Kinase Establishes Self-Tolerance in a Thymic Stroma-Dependent Manner
Fumiko Kajiura, Shijie Sun, Takashi Nomura, Keisuke Izumi, Tomoo Ueno, Yoshimi Bando, Noriyuki Kuroda, Hongwei Han, Yi Li, Akemi Matsushima, Yousuke Takahama, Shimon Sakaguchi, Tasuku Mitani and Mitsuru Matsumoto

J Immunol February 15, 2004, 172 (4) 2067-2075; DOI: https://doi.org/10.4049/jimmunol.172.4.2067
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Mechanisms Governing B Cell Developmental Defects in Invariant Chain-Deficient Mice
Kamel Benlagha, Se-Ho Park, Rodolphe Guinamard, Claire Forestier, Lars Karlsson, Cheong-Hee Chang and Albert Bendelac

J Immunol February 15, 2004, 172 (4) 2076-2083; DOI: https://doi.org/10.4049/jimmunol.172.4.2076
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B Cell Receptor-Mediated Apoptosis of Human Lymphocytes Is Associated with a New Regulatory Pathway of Bim Isoform Expression
Shahul Mouhamad, Laurence Besnault, Marie Thérèse Auffredou, Corinne Leprince, Marie Françoise Bourgeade, Gérald Leca and Aimé Vazquez

J Immunol February 15, 2004, 172 (4) 2084-2091; DOI: https://doi.org/10.4049/jimmunol.172.4.2084
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Transgenic Expression of a Human Polyreactive Ig Expressed in Chronic Lymphocytic Leukemia Generates Memory-Type B Cells That Respond to Nonspecific Immune Activation
George F. Widhopf II, Diana C. Brinson, Thomas J. Kipps and Helen Tighe

J Immunol February 15, 2004, 172 (4) 2092-2099; DOI: https://doi.org/10.4049/jimmunol.172.4.2092
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Severely Impaired B Lymphocyte Proliferation, Survival, and Induction of the c-Myc:Cullin 1 Ubiquitin Ligase Pathway Resulting from CD22 Deficiency on the C57BL/6 Genetic Background
Jonathan C. Poe, Karen M. Haas, Junji Uchida, Youngkyun Lee, Manabu Fujimoto and Thomas F. Tedder

J Immunol February 15, 2004, 172 (4) 2100-2110; DOI: https://doi.org/10.4049/jimmunol.172.4.2100
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Distinct Expression Profiles of the Peripheral Cannabinoid Receptor in Lymphoid Tissues Depending on Receptor Activation Status
Nazik Rayman, King H. Lam, Jon D. Laman, Peter J. Simons, Bob Löwenberg, Pieter Sonneveld and Ruud Delwel

J Immunol February 15, 2004, 172 (4) 2111-2117; DOI: https://doi.org/10.4049/jimmunol.172.4.2111
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Complete Loss of Fas Ligand Gene Causes Massive Lymphoproliferation and Early Death, Indicating a Residual Activity of gld Allele
Saoussen Karray, Chantal Kress, Sylvain Cuvellier, Catherine Hue-Beauvais, Diane Damotte, Charles Babinet and Matthieu Lévi-Strauss

J Immunol February 15, 2004, 172 (4) 2118-2125; DOI: https://doi.org/10.4049/jimmunol.172.4.2118
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Exosomes as Potent Cell-Free Peptide-Based Vaccine. I. Dendritic Cell-Derived Exosomes Transfer Functional MHC Class I/Peptide Complexes to Dendritic Cells
Fabrice André, Nathalie Chaput, Nöel E. C. Schartz, Caroline Flament, Nathalie Aubert, Jacky Bernard, François Lemonnier, Graça Raposo, Bernard Escudier, Di-Hwei Hsu, Thomas Tursz, Sebastian Amigorena, Eric Angevin and Laurence Zitvogel

J Immunol February 15, 2004, 172 (4) 2126-2136; DOI: https://doi.org/10.4049/jimmunol.172.4.2126
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Exosomes as Potent Cell-Free Peptide-Based Vaccine. II. Exosomes in CpG Adjuvants Efficiently Prime Naive Tc1 Lymphocytes Leading to Tumor Rejection
Nathalie Chaput, Nöel E. C. Schartz, Fabrice André, Julien Taïeb, Sophie Novault, Pierre Bonnaventure, Nathalie Aubert, Jacky Bernard, François Lemonnier, Miriam Merad, Gosse Adema, Malcolm Adams, Maria Ferrantini, Antoine F. Carpentier, Bernard Escudier, Thomas Tursz, Eric Angevin and Laurence Zitvogel

J Immunol February 15, 2004, 172 (4) 2137-2146; DOI: https://doi.org/10.4049/jimmunol.172.4.2137
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Novel Regulatory Mechanisms of CD40-Induced Prostanoid Synthesis by IL-4 and IL-10 in Human Monocytes
Yasushi Inoue, Takeshi Otsuka, Hiroaki Niiro, Shuji Nagano, Yojirou Arinobu, Eiichi Ogami, Mitsuteru Akahoshi, Katsuhisa Miyake, Ichiro Ninomiya, Sakiko Shimizu, Hitoshi Nakashima and Mine Harada

J Immunol February 15, 2004, 172 (4) 2147-2154; DOI: https://doi.org/10.4049/jimmunol.172.4.2147
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Reduced Ig Class Switch in Aged Mice Correlates with Decreased E47 and Activation-Induced Cytidine Deaminase
Daniela Frasca, Elaine Van der Put, Richard L. Riley and Bonnie B. Blomberg

J Immunol February 15, 2004, 172 (4) 2155-2162; DOI: https://doi.org/10.4049/jimmunol.172.4.2155
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Dependency of Direct Pathway CD4⁺ T Cells on CD40-CD154 Costimulation Is Determined by Nature and Microenvironment of Primary Contact with Alloantigen
Andre van Maurik, Barbara Fazekas de St. Groth, Kathryn J. Wood and Nick D. Jones

J Immunol February 15, 2004, 172 (4) 2163-2170; DOI: https://doi.org/10.4049/jimmunol.172.4.2163
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Disparate In Vitro and In Vivo Requirements for IL-2 During Antigen-Independent CD8 T Cell Expansion
Phillip Wong and Eric G. Pamer

J Immunol February 15, 2004, 172 (4) 2171-2176; DOI: https://doi.org/10.4049/jimmunol.172.4.2171
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A Novel Role for an Insect Apolipoprotein (Apolipophorin III) in β-1,3-Glucan Pattern Recognition and Cellular Encapsulation Reactions
Miranda M. A. Whitten, Ian F. Tew, Bok L. Lee and Norman A. Ratcliffe

J Immunol February 15, 2004, 172 (4) 2177-2185; DOI: https://doi.org/10.4049/jimmunol.172.4.2177
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Extremely Rapid and Intense Induction of Apoptosis in Human Eosinophils by Anti-CD30 Antibody Treatment In Vitro
Kenji Matsumoto, Maki Terakawa, Kenju Miura, Shuhei Fukuda, Toshiharu Nakajima and Hirohisa Saito

J Immunol February 15, 2004, 172 (4) 2186-2193; DOI: https://doi.org/10.4049/jimmunol.172.4.2186
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Resistance of Short Term Activated T Cells to CD95-Mediated Apoptosis Correlates with De Novo Protein Synthesis of c-FLIP_short
Ingo Schmitz, Heiko Weyd, Andreas Krueger, Sven Baumann, Stefanie C. Fas, Peter H. Krammer and Sabine Kirchhoff

J Immunol February 15, 2004, 172 (4) 2194-2200; DOI: https://doi.org/10.4049/jimmunol.172.4.2194
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IL-10-Conditioned Dendritic Cells, Decommissioned for Recruitment of Adaptive Immunity, Elicit Innate Inflammatory Gene Products in Response to Danger Signals
Kathleen F. Nolan, Victoria Strong, Dulce Soler, Paul J. Fairchild, Stephen P. Cobbold, Ruth Croxton, Jose-Angel Gonzalo, Ana Rubio, Meghan Wells and Herman Waldmann

J Immunol February 15, 2004, 172 (4) 2201-2209; DOI: https://doi.org/10.4049/jimmunol.172.4.2201
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The Cytoplasmic Domain of Igα Is Necessary and Sufficient to Support Efficient Early B Cell Development
Kelly A. Pike, Sandra Iacampo, Jennifer E. Friedmann and Michael J. H. Ratcliffe

J Immunol February 15, 2004, 172 (4) 2210-2218; DOI: https://doi.org/10.4049/jimmunol.172.4.2210
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HIV-Infected Langerhans Cells Preferentially Transmit Virus to Proliferating Autologous CD4⁺ Memory T Cells Located within Langerhans Cell-T Cell Clusters
Makoto Sugaya, Karin Loré, Richard A. Koup, Daniel C. Douek and Andrew Blauvelt

J Immunol February 15, 2004, 172 (4) 2219-2224; DOI: https://doi.org/10.4049/jimmunol.172.4.2219
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WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27
Stefan Pflanz, Linda Hibbert, Jeanine Mattson, Rency Rosales, Elena Vaisberg, J. Fernando Bazan, Joseph H. Phillips, Terrill K. McClanahan, Rene de Waal Malefyt and Robert A. Kastelein

J Immunol February 15, 2004, 172 (4) 2225-2231; DOI: https://doi.org/10.4049/jimmunol.172.4.2225
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Identification of New Antigenic Peptide Presented by HLA-Cw7 and Encoded by Several MAGE Genes Using Dendritic Cells Transduced with Lentiviruses
Karine Breckpot, Carlo Heirman, Catherine De Greef, Pierre van der Bruggen and Kris Thielemans

J Immunol February 15, 2004, 172 (4) 2232-2237; DOI: https://doi.org/10.4049/jimmunol.172.4.2232
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Antigen Nonspecific Suppression of T Cell Responses by Activated Stimulation-Refractory CD4⁺ T Cells
Christine T. Duthoit, Phuong Nguyen and Terrence L. Geiger

J Immunol February 15, 2004, 172 (4) 2238-2246; DOI: https://doi.org/10.4049/jimmunol.172.4.2238
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The Impact of Thymic Antigen Diversity on the Size of the Selected T Cell Repertoire
Jose Faro, Santiago Velasco, África González-Fernández and Antonio Bandeira

J Immunol February 15, 2004, 172 (4) 2247-2255; DOI: https://doi.org/10.4049/jimmunol.172.4.2247
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Human Cytomegalovirus Proteins pp65 and Immediate Early Protein 1 Are Common Targets for CD8⁺ T Cell Responses in Children with Congenital or Postnatal Human Cytomegalovirus Infection
Laura Gibson, Giampiero Piccinini, Daniele Lilleri, Maria Grazia Revello, Zhongde Wang, Susan Markel, Don J. Diamond and Katherine Luzuriaga

J Immunol February 15, 2004, 172 (4) 2256-2264; DOI: https://doi.org/10.4049/jimmunol.172.4.2256
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NF-κB Controls Cell Fate Specification, Survival, and Molecular Differentiation of Immunoregulatory Natural T Lymphocytes
Aleksandar K. Stanic, Jelena S. Bezbradica, Jang-June Park, Naoto Matsuki, Ana L. Mora, Luc Van Kaer, Mark R. Boothby and Sebastian Joyce

J Immunol February 15, 2004, 172 (4) 2265-2273; DOI: https://doi.org/10.4049/jimmunol.172.4.2265
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Adjuvant Costimulation during Secondary Antigen Challenge Directs Qualitative Aspects of Oral Tolerance Induction, Particularly during the Neonatal Period
Iriani T. Tobagus, Wayne R. Thomas and Patrick G. Holt

J Immunol February 15, 2004, 172 (4) 2274-2285; DOI: https://doi.org/10.4049/jimmunol.172.4.2274
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CD4⁺ T Cells Regulate CD8⁺ T Cell-Mediated Cutaneous Immune Responses by Restricting Effector T Cell Development through a Fas Ligand-Dependent Mechanism
Anton V. Gorbachev and Robert L. Fairchild

J Immunol February 15, 2004, 172 (4) 2286-2295; DOI: https://doi.org/10.4049/jimmunol.172.4.2286
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Reduced Thymocyte Development in Sonic Hedgehog Knockout Embryos
Divya K. Shah, Ariadne L. Hager-Theodorides, Susan V. Outram, Susan E. Ross, Alberto Varas and Tessa Crompton

J Immunol February 15, 2004, 172 (4) 2296-2306; DOI: https://doi.org/10.4049/jimmunol.172.4.2296

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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Dendritic Cell Maturation Requires STAT1 and Is under Feedback Regulation by Suppressors of Cytokine Signaling
Sharon H. Jackson, Cheng-Rong Yu, Rashid M. Mahdi, Samuel Ebong and Charles E. Egwuagu

J Immunol February 15, 2004, 172 (4) 2307-2315; DOI: https://doi.org/10.4049/jimmunol.172.4.2307
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Caspase-3 Is a Component of Fas Death-Inducing Signaling Complex in Lipid Rafts and Its Activity Is Required for Complete Caspase-8 Activation during Fas-Mediated Cell Death
Salah M. Aouad, Luchino Y. Cohen, Ehsan Sharif-Askari, Elias K. Haddad, Antoine Alam and Rafick-Pierre Sekaly

J Immunol February 15, 2004, 172 (4) 2316-2323; DOI: https://doi.org/10.4049/jimmunol.172.4.2316
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The Impact of Self-Tolerance on the Polyclonal CD8⁺ T Cell Repertoire
Helmut W. H. G. Kessels, Karin E. de Visser, Felicia H. Tirion, Miriam Coccoris, Ada M. Kruisbeek and Ton N. M. Schumacher

J Immunol February 15, 2004, 172 (4) 2324-2331; DOI: https://doi.org/10.4049/jimmunol.172.4.2324
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Activation of Discoidin Domain Receptor 1 Isoform b with Collagen Up-Regulates Chemokine Production in Human Macrophages: Role of p38 Mitogen-Activated Protein Kinase and NF-κB
Wataru Matsuyama, Lihua Wang, William L. Farrar, Michel Faure and Teizo Yoshimura

J Immunol February 15, 2004, 172 (4) 2332-2340; DOI: https://doi.org/10.4049/jimmunol.172.4.2332
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Immunosuppressive Activity of Endovanilloids: N-Arachidonoyl-Dopamine Inhibits Activation of the NF-κB, NFAT, and Activator Protein 1 Signaling Pathways
Rocío Sancho, Antonio Macho, Laureano de La Vega, Marco A. Calzado, Bernd L. Fiebich, Giovanni Appendino and Eduardo Muñoz

J Immunol February 15, 2004, 172 (4) 2341-2351; DOI: https://doi.org/10.4049/jimmunol.172.4.2341
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Molecular Characterization of Human 4Ig-B7-H3, a Member of the B7 Family with Four Ig-Like Domains
Peter Steinberger, Otto Majdic, Sophia V. Derdak, Katharina Pfistershammer, Stefanie Kirchberger, Christoph Klauser, Gerhard Zlabinger, Winfried F. Pickl, Johannes Stöckl and Walter Knapp

J Immunol February 15, 2004, 172 (4) 2352-2359; DOI: https://doi.org/10.4049/jimmunol.172.4.2352
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Biases in Ig λ Light Chain Rearrangements in Human Intestinal Plasma Cells
Wen Su, Laurent Boursier, Archana Padala, Jeremy D. Sanderson and Jo Spencer

J Immunol February 15, 2004, 172 (4) 2360-2366; DOI: https://doi.org/10.4049/jimmunol.172.4.2360
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Conformation and Glycosylation of a Megalin Fragment Correlate with Nephritogenicity in Heymann Nephritis
Alfonso Tramontano and Sudesh P. Makker

J Immunol February 15, 2004, 172 (4) 2367-2373; DOI: https://doi.org/10.4049/jimmunol.172.4.2367
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FcεRIγ-ITAM Is Differentially Required for Mast Cell Function In Vivo
Daiju Sakurai, Sho Yamasaki, Kanako Arase, Seung Yong Park, Hisashi Arase, Akiyoshi Konno and Takashi Saito

J Immunol February 15, 2004, 172 (4) 2374-2381; DOI: https://doi.org/10.4049/jimmunol.172.4.2374
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The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid
Thil Batuwangala, Dawn Shepherd, Stephan D. Gadola, Kevin J. C. Gibson, Nathan R. Zaccai, Alan R. Fersht, Gurdyal S. Besra, Vincenzo Cerundolo and E. Yvonne Jones

J Immunol February 15, 2004, 172 (4) 2382-2388; DOI: https://doi.org/10.4049/jimmunol.172.4.2382
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Activation/Division of Lymphocytes Results in Increased Levels of Cytoplasmic Activation/Proliferation-Associated Protein-1: Prototype of a New Family of Proteins
Brock Grill, Gary M. Wilson, Kai-Xin Zhang, Bin Wang, Regis Doyonnas, Manfredo Quadroni and John W. Schrader

J Immunol February 15, 2004, 172 (4) 2389-2400; DOI: https://doi.org/10.4049/jimmunol.172.4.2389

HOST DEFENSE

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Antibody-Dependent Cellular Cytotoxicity via Humoral Immune Epitope of Nef Protein Expressed on Cell Surface
Takeshi Yamada, Nobukazu Watanabe, Tetsuya Nakamura and Aikichi Iwamoto

J Immunol February 15, 2004, 172 (4) 2401-2406; DOI: https://doi.org/10.4049/jimmunol.172.4.2401
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Macrophages, CD4⁺ or CD8⁺ Cells Are Each Sufficient for Protection against Chlamydia pneumoniae Infection through their Ability to Secrete IFN-γ
Antonio Gigliotti Rothfuchs, Maria Regina Kreuger, Hans Wigzell and Martin E. Rottenberg

J Immunol February 15, 2004, 172 (4) 2407-2415; DOI: https://doi.org/10.4049/jimmunol.172.4.2407
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Calcium and Its Role in the Nuclear Translocation and Activation of Cytosolic Phospholipase A₂ in Cells Rendered Sensitive to TNF-Induced Apoptosis by Cycloheximide
David W. Draper, Virginia G. Harris, Carolyn A. Culver and Scott M. Laster

J Immunol February 15, 2004, 172 (4) 2416-2423; DOI: https://doi.org/10.4049/jimmunol.172.4.2416
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Peripheral CD4 T Cells Rapidly Accumulate at the Host:Parasite Interface during an Inflammatory Th2 Memory Response
Motoko Morimoto, Masahiro Morimoto, Jeannette Whitmire, Shiyun Xiao, Robert M. Anthony, Hiroshi Mirakami, Robert A. Star, Joseph F. Urban Jr and William C. Gause

J Immunol February 15, 2004, 172 (4) 2424-2430; DOI: https://doi.org/10.4049/jimmunol.172.4.2424
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Haemophilus influenzae Type b-Outer Membrane Protein Complex Glycoconjugate Vaccine Induces Cytokine Production by Engaging Human Toll-Like Receptor 2 (TLR2) and Requires the Presence of TLR2 for Optimal Immunogenicity
Eicke Latz, Jennifer Franko, Douglas T. Golenbock and John R. Schreiber

J Immunol February 15, 2004, 172 (4) 2431-2438; DOI: https://doi.org/10.4049/jimmunol.172.4.2431
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Parasite Antigen-Driven Basophils Are a Major Source of IL-4 in Human Filarial Infections
Edward Mitre, Rebekah T. Taylor, Joseph Kubofcik and Thomas B. Nutman

J Immunol February 15, 2004, 172 (4) 2439-2445; DOI: https://doi.org/10.4049/jimmunol.172.4.2439
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The Zinc Finger Mutation C417R of I-κB Kinase γ Impairs Lipopolysaccharide- and TNF-Mediated NF-κB Activation through Inhibiting Phosphorylation of the I-κB Kinase β Activation Loop
Fan Yang, Junro Yamashita, Eric Tang, Hom-lay Wang, Kunliang Guan and Cun-Yu Wang

J Immunol February 15, 2004, 172 (4) 2446-2452; DOI: https://doi.org/10.4049/jimmunol.172.4.2446
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Recognition of Homo- and Heterosubtypic Variants of Influenza A Viruses by Human CD8⁺ T Lymphocytes
Adrianus C. M. Boon, Gerrie de Mutsert, Debbie van Baarle, Derek J. Smith, Alan S. Lapedes, Ron A. M. Fouchier, Kees Sintnicolaas, Albert D. M. E. Osterhaus and Guus F. Rimmelzwaan

J Immunol February 15, 2004, 172 (4) 2453-2460; DOI: https://doi.org/10.4049/jimmunol.172.4.2453
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Protective Immunization against Group B Meningococci Using Anti-Idiotypic Mimics of the Capsular Polysaccharide
Concetta Beninati, Simona Arseni, Giuseppe Mancuso, Walter Magliani, Stefania Conti, Angelina Midiri, Carmelo Biondo, Luciano Polonelli and Giuseppe Teti

J Immunol February 15, 2004, 172 (4) 2461-2468; DOI: https://doi.org/10.4049/jimmunol.172.4.2461
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Cyclooxygenase-2-Mediated Prostaglandin E₂ Production in Mesenteric Lymph Nodes and in Cultured Macrophages and Dendritic Cells after Infection with Salmonella
Christal C. Bowman and Kenneth L. Bost

J Immunol February 15, 2004, 172 (4) 2469-2475; DOI: https://doi.org/10.4049/jimmunol.172.4.2469
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HIV-1-Specific Memory CD4⁺ T Cells Are Phenotypically Less Mature Than Cytomegalovirus-Specific Memory CD4⁺ T Cells
Feng Yun Yue, Colin M. Kovacs, Rowena C. Dimayuga, Paul Parks and Mario A. Ostrowski

J Immunol February 15, 2004, 172 (4) 2476-2486; DOI: https://doi.org/10.4049/jimmunol.172.4.2476
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Protective T Cell Immunity against Malaria Liver Stage after Vaccination with Live Sporozoites under Chloroquine Treatment
Elodie Belnoue, Fabio T. M. Costa, Tobias Frankenberg, Ana Margarida Vigário, Tatiana Voza, Nicolas Leroy, Mauricio M. Rodrigues, Irène Landau, Georges Snounou and Laurent Rénia

J Immunol February 15, 2004, 172 (4) 2487-2495; DOI: https://doi.org/10.4049/jimmunol.172.4.2487
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Liver Dendritic Cells Present Bacterial Antigens and Produce Cytokines upon Salmonella Encounter
Cecilia Johansson and Mary Jo Wick

J Immunol February 15, 2004, 172 (4) 2496-2503; DOI: https://doi.org/10.4049/jimmunol.172.4.2496

INFLAMMATION

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Suppression of Osteoprotegerin Expression by Prostaglandin E₂ Is Crucially Involved in Lipopolysaccharide-Induced Osteoclast Formation
Koji Suda, Nobuyuki Udagawa, Nobuaki Sato, Masamichi Takami, Kanami Itoh, Je-Tae Woo, Naoyuki Takahashi and Kazuo Nagai

J Immunol February 15, 2004, 172 (4) 2504-2510; DOI: https://doi.org/10.4049/jimmunol.172.4.2504
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TNF Receptor Signaling Contributes to Chemokine Secretion, Inflammation, and Respiratory Deficits during Pneumocystis Pneumonia
Terry W. Wright, Gloria S. Pryhuber, Patricia R. Chess, Zhengdong Wang, Robert H. Notter and Francis Gigliotti

J Immunol February 15, 2004, 172 (4) 2511-2521; DOI: https://doi.org/10.4049/jimmunol.172.4.2511
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Involvement of Reactive Oxygen Species in Toll-Like Receptor 4-Dependent Activation of NF-κB
Karim Asehnoune, Derek Strassheim, Sanchayita Mitra, Jae Yeol Kim and Edward Abraham

J Immunol February 15, 2004, 172 (4) 2522-2529; DOI: https://doi.org/10.4049/jimmunol.172.4.2522
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B7-DC Regulates Asthmatic Response by an IFN-γ-Dependent Mechanism
Koichiro Matsumoto, Hiromasa Inoue, Takako Nakano, Miyuki Tsuda, Yuki Yoshiura, Satoru Fukuyama, Fumihiko Tsushima, Tomoaki Hoshino, Hisamichi Aizawa, Hisaya Akiba, Drew Pardoll, Nobuyuki Hara, Hideo Yagita, Miyuki Azuma and Yoichi Nakanishi

J Immunol February 15, 2004, 172 (4) 2530-2541; DOI: https://doi.org/10.4049/jimmunol.172.4.2530
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Role of Bradykinin B₂ and B₁ Receptors in the Local, Remote, and Systemic Inflammatory Responses That Follow Intestinal Ischemia and Reperfusion Injury
Danielle G. Souza, Eliane S. L. Lomez, Vanessa Pinho, João Bosco Pesquero, Michael Bader, Jorge Luís Pesquero and Mauro M. Teixeira

J Immunol February 15, 2004, 172 (4) 2542-2548; DOI: https://doi.org/10.4049/jimmunol.172.4.2542
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Contribution of Antigen-Primed CD8⁺ T Cells to the Development of Airway Hyperresponsiveness and Inflammation Is Associated with IL-13
Nobuaki Miyahara, Katsuyuki Takeda, Taku Kodama, Anthony Joetham, Christian Taube, Jung-Won Park, Satoko Miyahara, Annette Balhorn, Azzeddine Dakhama and Erwin W. Gelfand

J Immunol February 15, 2004, 172 (4) 2549-2558; DOI: https://doi.org/10.4049/jimmunol.172.4.2549
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Microtubule-Associated Serine/Threonine Kinase-205 kDa and Fcγ Receptor Control IL-12 p40 Synthesis and NF-κB Activation
Hui Zhou, Huabao Xiong, Hongxing Li, Scott E. Plevy, Paul D. Walden, Massimo Sassaroli, Glenn D. Prestwich and Jay C. Unkeless

J Immunol February 15, 2004, 172 (4) 2559-2568; DOI: https://doi.org/10.4049/jimmunol.172.4.2559
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Inhibition of c-Jun NH₂-Terminal Kinase Activity Improves Ischemia/Reperfusion Injury in Rat Lungs
Makoto Ishii, Yukio Suzuki, Kei Takeshita, Naoki Miyao, Hiroyasu Kudo, Rika Hiraoka, Kazumi Nishio, Nagato Sato, Katsuhiko Naoki, Takuya Aoki and Kazuhiro Yamaguchi

J Immunol February 15, 2004, 172 (4) 2569-2577; DOI: https://doi.org/10.4049/jimmunol.172.4.2569
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Peptide-Mediated Inhibition of Neutrophil Transmigration by Blocking CD47 Interactions with Signal Regulatory Protein α
Yuan Liu, Miriam B. O’Connor, Kenneth J. Mandell, Ke Zen, Axel Ullrich, Hans-Jörg Bühring and Charles A. Parkos

J Immunol February 15, 2004, 172 (4) 2578-2585; DOI: https://doi.org/10.4049/jimmunol.172.4.2578
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Matrix Metalloproteinase-9 Deficiency Results in Enhanced Allergen-Induced Airway Inflammation
Sarah J. McMillan, Jennifer Kearley, J. Darren Campbell, Xing-Wu Zhu, Karen Y. Larbi, J. Michael Shipley, Robert M. Senior, Sussan Nourshargh and Clare M. Lloyd

J Immunol February 15, 2004, 172 (4) 2586-2594; DOI: https://doi.org/10.4049/jimmunol.172.4.2586
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Inflammatory Gene Profiles in Gastric Mucosa during Helicobacter pylori Infection in Humans
Sicheng Wen, Christian P. Felley, Hanifa Bouzourene, Mark Reimers, Pierre Michetti and Qiang Pan-Hammarström

J Immunol February 15, 2004, 172 (4) 2595-2606; DOI: https://doi.org/10.4049/jimmunol.172.4.2595
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Key Roles of CD4⁺ T Cells and IFN-γ in the Development of Abdominal Aortic Aneurysms in a Murine Model
Wanfen Xiong, Yong Zhao, Amy Prall, Timothy C. Greiner and B. Timothy Baxter

J Immunol February 15, 2004, 172 (4) 2607-2612; DOI: https://doi.org/10.4049/jimmunol.172.4.2607
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Inhibition of IL-10 Receptor Function in Alveolar Macrophages by Toll-Like Receptor Agonists
Stefan Fernandez, Purnima Jose, Margarita G. Avdiushko, Alan M. Kaplan and Donald A. Cohen

J Immunol February 15, 2004, 172 (4) 2613-2620; DOI: https://doi.org/10.4049/jimmunol.172.4.2613
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Construction of Hevein (Hev b 6.02) with Reduced Allergenicity for Immunotherapy of Latex Allergy by Comutation of Six Amino Acid Residues on the Conformational IgE Epitopes
Piia Karisola, Jari Mikkola, Nisse Kalkkinen, Kari J. Airenne, Olli H. Laitinen, Susanna Repo, Olli T. Pentikäinen, Timo Reunala, Kristiina Turjanmaa, Mark S. Johnson, Timo Palosuo, Markku S. Kulomaa and Harri Alenius

J Immunol February 15, 2004, 172 (4) 2621-2628; DOI: https://doi.org/10.4049/jimmunol.172.4.2621
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Role of Toll-Like Receptor 4 in Endotoxin-Induced Acute Renal Failure
Patrick N. Cunningham, Ying Wang, Rongqing Guo, Gang He and Richard J. Quigg

J Immunol February 15, 2004, 172 (4) 2629-2635; DOI: https://doi.org/10.4049/jimmunol.172.4.2629

CLINICAL IMMUNOLOGY

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Respective Roles of Decay-Accelerating Factor and CD59 in Circumventing Glomerular Injury in Acute Nephrotoxic Serum Nephritis
Feng Lin, David J. Salant, Howard Meyerson, Steven Emancipator, B. Paul Morgan and M. Edward Medof

J Immunol February 15, 2004, 172 (4) 2636-2642; DOI: https://doi.org/10.4049/jimmunol.172.4.2636
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TNF-α Coupled to Membrane of Apoptotic Cells Favors the Cross-Priming to Melanoma Antigens
Valérie S. Zimmermann, Attilio Bondanza, Antonella Monno, Patrizia Rovere-Querini, Angelo Corti and Angelo A. Manfredi

J Immunol February 15, 2004, 172 (4) 2643-2650; DOI: https://doi.org/10.4049/jimmunol.172.4.2643
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A Spontaneous Model for Autoimmune Myocarditis Using the Human MHC Molecule HLA-DQ8
Jacqueline A. Taylor, Evis Havari, Marcia F. McInerney, Roderick Bronson, Kai W. Wucherpfennig and Myra A. Lipes

J Immunol February 15, 2004, 172 (4) 2651-2658; DOI: https://doi.org/10.4049/jimmunol.172.4.2651
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In Vivo Evidence That Peptide Vaccination Can Induce HLA-DR-Restricted CD4⁺ T Cells Reactive to a Class I Tumor Peptide
Mamoru Harada, Rumi Gohara, Satoko Matsueda, Akira Muto, Tatsuya Oda, Yoshiko Iwamoto and Kyogo Itoh

J Immunol February 15, 2004, 172 (4) 2659-2667; DOI: https://doi.org/10.4049/jimmunol.172.4.2659
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Pulmonary Edema Fluid from Patients with Early Lung Injury Stimulates Fibroblast Proliferation through IL-1β-Induced IL-6 Expression
Mitchell A. Olman, Kimberly E. White, Lorraine B. Ware, Warren L. Simmons, Etty N. Benveniste, Sha Zhu, Jerome Pugin and Michael A. Matthay

J Immunol February 15, 2004, 172 (4) 2668-2677; DOI: https://doi.org/10.4049/jimmunol.172.4.2668
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CD40 Ligand Dysregulation in HIV Infection: HIV Glycoprotein 120 Inhibits Signaling Cascades Upstream of CD40 Ligand Transcription
Rui Zhang, Carl J. Fichtenbaum, David A. Hildeman, Jeffrey D. Lifson and Claire Chougnet

J Immunol February 15, 2004, 172 (4) 2678-2686; DOI: https://doi.org/10.4049/jimmunol.172.4.2678
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HIV-1 Does Not Provoke Alteration of Cytokine Gene Expression in Lymphoid Tissue after Acute Infection Ex Vivo
Annette Audigé, Erika Schlaepfer, Athos Bonanomi, Helene Joller, Marlyse C. Knuchel, Markus Weber, David Nadal and Roberto F. Speck

J Immunol February 15, 2004, 172 (4) 2687-2696; DOI: https://doi.org/10.4049/jimmunol.172.4.2687
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Breakdown of Tolerance to a Self-Peptide of Acetylcholine Receptor α-Subunit Induces Experimental Myasthenia Gravis in Rats
Fulvio Baggi, Andrea Annoni, Federica Ubiali, Monica Milani, Renato Longhi, Widmer Scaioli, Ferdinando Cornelio, Renato Mantegazza and Carlo Antozzi

J Immunol February 15, 2004, 172 (4) 2697-2703; DOI: https://doi.org/10.4049/jimmunol.172.4.2697

CORRECTIONS

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Molecular Cloning and Immunologic Characterization of a Novel cDNA Coding for Progesterone-Induced Blocking Factor
Beata Polgar, Gyula Kispal, Margit Lachmann, Gabriella Paar, Eszter Nagy, Peter Csere, Eva Miko, Laszlo Szereday, Peter Varga and Julia Szekeres-Bartho

J Immunol February 15, 2004, 172 (4) 2704; DOI: https://doi.org/10.4049/jimmunol.172.4.2704
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The Cationic Antimicrobial Peptide LL-37 Modulates Dendritic Cell Differentiation and Dendritic Cell-Induced T Cell Polarization
Donald J. Davidson, Andrew J. Currie, Gregor S. D. Reid, Dawn M. E. Bowdish, Kelly L. MacDonald, Rebecca C. Ma, Robert E. W. Hancock and David P. Speert

J Immunol February 15, 2004, 172 (4) 2704; DOI: https://doi.org/10.4049/jimmunol.172.4.2704-a
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Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands
Matthias Pierer, Janine Rethage, Reinhart Seibl, Roger Lauener, Fabia Brentano, Ulf Wagner, Holm Hantzschel, Beat A. Michel, Renate E. Gay, Steffen Gay and Diego Kyburz

J Immunol February 15, 2004, 172 (4) 2704; DOI: https://doi.org/10.4049/jimmunol.172.4.2704-b

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IN THIS ISSUE

CUTTING EDGE

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

MOLECULAR AND STRUCTURAL IMMUNOLOGY

HOST DEFENSE

INFLAMMATION

CLINICAL IMMUNOLOGY

CORRECTIONS

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