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The Journal of Immunology

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Table of Contents

May 15, 2004; Volume 172,Issue 10

IN THIS ISSUE

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    IN THIS ISSUE
    J Immunol May 15, 2004, 172 (10) 5811-5812; DOI: https://doi.org/10.4049/jimmunol.172.10.5811

LETTERS TO THE EDITOR

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    A. actinomycetemcomitans Cytolethal Distending Toxin
    Monica Thelestam and Teresa Frisan
    J Immunol May 15, 2004, 172 (10) 5813; DOI: https://doi.org/10.4049/jimmunol.172.10.5813
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    The Authors Respond
    Bruce J. Shenker and Donald Demuth
    J Immunol May 15, 2004, 172 (10) 5813-5814; DOI: https://doi.org/10.4049/jimmunol.172.10.5813-a

BRIEF REVIEWS

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    DNA Acrobats of the Ig Class Switch
    Clifford L. Wang and Matthias Wabl
    J Immunol May 15, 2004, 172 (10) 5815-5821; DOI: https://doi.org/10.4049/jimmunol.172.10.5815

CUTTING EDGE

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    Cutting Edge: The Natural Ligand for Glucocorticoid-Induced TNF Receptor-Related Protein Abrogates Regulatory T Cell Suppression
    Hong-bin Ji, Gongxian Liao, William A. Faubion, Ana C. Abadía-Molina, Cristina Cozzo, F. Stephen Laroux, Andrew Caton and Cox Terhorst
    J Immunol May 15, 2004, 172 (10) 5823-5827; DOI: https://doi.org/10.4049/jimmunol.172.10.5823
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    Cutting Edge: Extracellular Signal-Regulated Kinases 1/2 Function as Integrators of TCR Signal Strength
    Andrew E. Schade and Alan D. Levine
    J Immunol May 15, 2004, 172 (10) 5828-5832; DOI: https://doi.org/10.4049/jimmunol.172.10.5828
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    Cutting Edge: C3d Functions as a Molecular Adjuvant in the Absence of CD21/35 Expression
    Karen M. Haas, Franklin R. Toapanta, Julie A. Oliver, Jonathan C. Poe, John H. Weis, David R. Karp, Joseph F. Bower, Ted M. Ross and Thomas F. Tedder
    J Immunol May 15, 2004, 172 (10) 5833-5837; DOI: https://doi.org/10.4049/jimmunol.172.10.5833
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    Cutting Edge: TREM-Like Transcript-1, a Platelet Immunoreceptor Tyrosine-Based Inhibition Motif Encoding Costimulatory Immunoreceptor that Enhances, Rather than Inhibits, Calcium Signaling via SHP-2
    Alexander D. Barrow, Emmanuelle Astoul, Andres Floto, Gary Brooke, Ingrid A. M. Relou, Nicola S. Jennings, Kenneth G. C. Smith, Willem Ouwehand, Richard W. Farndale, Denis R. Alexander and John Trowsdale
    J Immunol May 15, 2004, 172 (10) 5838-5842; DOI: https://doi.org/10.4049/jimmunol.172.10.5838

CELLULAR IMMUNOLOGY AND IMMUNE REGULATION

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    Shift from Systemic to Site-Specific Memory by Tumor-Targeted IL-2
    David Schrama, Rong Xiang, Andreas O. Eggert, Mads Hald Andersen, Lars Østergaard Pedersen, Eckhart Kämpgen, Ton N. Schumacher, Ralph R. Reisfeld and Jürgen C. Becker
    J Immunol May 15, 2004, 172 (10) 5843-5850; DOI: https://doi.org/10.4049/jimmunol.172.10.5843
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    Evolutionary Origins of Lymphocytes: Ensembles of T Cell and B Cell Transcriptional Regulators in a Cartilaginous Fish
    Michele K. Anderson, Rashmi Pant, Ann L. Miracle, Xiao Sun, Carl A. Luer, Catherine J. Walsh, Janice C. Telfer, Gary W. Litman and Ellen V. Rothenberg
    J Immunol May 15, 2004, 172 (10) 5851-5860; DOI: https://doi.org/10.4049/jimmunol.172.10.5851
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    CpG Motifs as Proinflammatory Factors Render Autochthonous Tumors Permissive for Infiltration and Destruction
    Natalio Garbi, Bernd Arnold, Siamon Gordon, Günter J. Hämmerling and Ruth Ganss
    J Immunol May 15, 2004, 172 (10) 5861-5869; DOI: https://doi.org/10.4049/jimmunol.172.10.5861
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    Differential Gene Expression Patterns by Oligonucleotide Microarray of Basal versus Lipopolysaccharide-Activated Monocytes from Cord Blood versus Adult Peripheral Blood
    Hong Jiang, Carmella Van de Ven, Prakash Satwani, Laxmi V. Baxi and Mitchell S. Cairo
    J Immunol May 15, 2004, 172 (10) 5870-5879; DOI: https://doi.org/10.4049/jimmunol.172.10.5870
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    CD28 Signals in the Immature Immunological Synapse
    Pietro G. Andres, Kimberly C. Howland, Douglas Dresnek, Samuel Edmondson, Abul K. Abbas and Matthew F. Krummel
    J Immunol May 15, 2004, 172 (10) 5880-5886; DOI: https://doi.org/10.4049/jimmunol.172.10.5880
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    CD4 Raft Association and Signaling Regulate Molecular Clustering at the Immunological Synapse Site
    Fran Balamuth, Jennifer L. Brogdon and Kim Bottomly
    J Immunol May 15, 2004, 172 (10) 5887-5892; DOI: https://doi.org/10.4049/jimmunol.172.10.5887
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    Depletion of CD8+ Cells Abolishes the Pregnancy Protective Effect of Progesterone Substitution with Dydrogesterone in Mice by Altering the Th1/Th2 Cytokine Profile
    Sandra M. Blois, Ricarda Joachim, Judith Kandil, Ricardo Margni, Mareike Tometten, Burghard F. Klapp and Petra C. Arck
    J Immunol May 15, 2004, 172 (10) 5893-5899; DOI: https://doi.org/10.4049/jimmunol.172.10.5893
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    Generation of Anergic and Regulatory T Cells following Prolonged Exposure to a Harmless Antigen
    Tse-Ching Chen, Stephen P. Cobbold, Paul J. Fairchild and Herman Waldmann
    J Immunol May 15, 2004, 172 (10) 5900-5907; DOI: https://doi.org/10.4049/jimmunol.172.10.5900
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    Up-Regulation of CD1d Expression Restores the Immunoregulatory Function of NKT Cells and Prevents Autoimmune Diabetes in Nonobese Diabetic Mice
    Marika Falcone, Federica Facciotti, Nadia Ghidoli, Paolo Monti, Stefano Olivieri, Luca Zaccagnino, Ezio Bonifacio, Giulia Casorati, Francesca Sanvito and Nora Sarvetnick
    J Immunol May 15, 2004, 172 (10) 5908-5916; DOI: https://doi.org/10.4049/jimmunol.172.10.5908
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    The Inducible Costimulator Plays the Major Costimulatory Role in Humoral Immune Responses in the Absence of CD28
    Woong-Kyung Suh, Anna Tafuri, Nancy N. Berg-Brown, Arda Shahinian, Suzanne Plyte, Gordon S. Duncan, Hitoshi Okada, Andrew Wakeham, Bernhard Odermatt, Pamela S. Ohashi and Tak W. Mak
    J Immunol May 15, 2004, 172 (10) 5917-5923; DOI: https://doi.org/10.4049/jimmunol.172.10.5917
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    Heart, but Not Skin, Allografts from Donors Lacking Flt3 Ligand Exhibit Markedly Prolonged Survival Time
    Zhiliang Wang, Antonino Castellaneta, An De Creus, William J. Shufesky, Adrian E. Morelli and Angus W. Thomson
    J Immunol May 15, 2004, 172 (10) 5924-5930; DOI: https://doi.org/10.4049/jimmunol.172.10.5924
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    An Inhibitory Ig Superfamily Protein Expressed by Lymphocytes and APCs Is Also an Early Marker of Thymocyte Positive Selection
    Peggy Han, Olivia D. Goularte, Kevin Rufner, Beverley Wilkinson and Jonathan Kaye
    J Immunol May 15, 2004, 172 (10) 5931-5939; DOI: https://doi.org/10.4049/jimmunol.172.10.5931
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    Curcumin (Diferuloylmethane) Inhibits Receptor Activator of NF-κB Ligand-Induced NF-κB Activation in Osteoclast Precursors and Suppresses Osteoclastogenesis
    Alok C. Bharti, Yasunari Takada and Bharat B. Aggarwal
    J Immunol May 15, 2004, 172 (10) 5940-5947; DOI: https://doi.org/10.4049/jimmunol.172.10.5940
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    Conversion of CTLA-4 from Inhibitor to Activator of T Cells with a Bispecific Tandem Single-Chain Fv Ligand
    Joaquín Madrenas, Luan A. Chau, Wendy A. Teft, Paul W. Wu, Jason Jussif, Marion Kasaian, Beatriz M. Carreno and Vincent Ling
    J Immunol May 15, 2004, 172 (10) 5948-5956; DOI: https://doi.org/10.4049/jimmunol.172.10.5948
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    IL-4 Confers NK Stimulatory Capacity to Murine Dendritic Cells: A Signaling Pathway Involving KARAP/DAP12-Triggering Receptor Expressed on Myeloid Cell 2 Molecules
    Magali Terme, Elena Tomasello, Koji Maruyama, Florent Crépineau, Nathalie Chaput, Caroline Flament, Jean-Pierre Marolleau, Eric Angevin, Erwin F. Wagner, Benoı̂t Salomon, François A. Lemonnier, Hiro Wakasugi, Marco Colonna, Eric Vivier and Laurence Zitvogel
    J Immunol May 15, 2004, 172 (10) 5957-5966; DOI: https://doi.org/10.4049/jimmunol.172.10.5957
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    Autoreactive T Cells in Healthy Individuals
    Nancy A. Danke, David M. Koelle, Cassian Yee, Sucheta Beheray and William W. Kwok
    J Immunol May 15, 2004, 172 (10) 5967-5972; DOI: https://doi.org/10.4049/jimmunol.172.10.5967
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    IL-2 Induces a Competitive Survival Advantage in T Lymphocytes
    Hans Dooms, Estelle Kahn, Birgit Knoechel and Abul K. Abbas
    J Immunol May 15, 2004, 172 (10) 5973-5979; DOI: https://doi.org/10.4049/jimmunol.172.10.5973
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    Adult Human Liver Contains CD8pos T Cells with Naive Phenotype, but Is Not a Site for Conventional αβ T Cell Development
    Lucy Golden-Mason, Daniel C. Douek, Richard A. Koup, Jacinta Kelly, John E. Hegarty and Cliona O’Farrelly
    J Immunol May 15, 2004, 172 (10) 5980-5985; DOI: https://doi.org/10.4049/jimmunol.172.10.5980
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    IL-10-Secreting Regulatory T Cells Do Not Express Foxp3 but Have Comparable Regulatory Function to Naturally Occurring CD4+CD25+ Regulatory T Cells
    Pedro L. Vieira, Jillian R. Christensen, Sophie Minaee, Emma J. O’Neill, Franck J. Barrat, André Boonstra, Thomas Barthlott, Brigitta Stockinger, David C. Wraith and Anne O’Garra
    J Immunol May 15, 2004, 172 (10) 5986-5993; DOI: https://doi.org/10.4049/jimmunol.172.10.5986
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    Thymic Expression of a Gastritogenic Epitope Results in Positive Selection of Self-Reactive Pathogenic T Cells
    Karen L. Laurie, Nicole L. La Gruta, Norbert Koch, Ian R. van Driel and Paul A. Gleeson
    J Immunol May 15, 2004, 172 (10) 5994-6002; DOI: https://doi.org/10.4049/jimmunol.172.10.5994
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    Induction of foxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants
    Stephen P. Cobbold, Raquel Castejon, Elizabeth Adams, Diana Zelenika, Luis Graca, Susan Humm and Herman Waldmann
    J Immunol May 15, 2004, 172 (10) 6003-6010; DOI: https://doi.org/10.4049/jimmunol.172.10.6003
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    The Serotoninergic Receptors of Human Dendritic Cells: Identification and Coupling to Cytokine Release
    Marco Idzko, Elisabeth Panther, Christian Stratz, Tobias Müller, Hannes Bayer, Gernot Zissel, Thorsten Dürk, Stephan Sorichter, Francesco Di Virgilio, Michael Geissler, Bernd Fiebich, Yared Herouy, Peter Elsner, Johannes Norgauer and Davide Ferrari
    J Immunol May 15, 2004, 172 (10) 6011-6019; DOI: https://doi.org/10.4049/jimmunol.172.10.6011
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    The Role of IL-5 for Mature B-1 Cells in Homeostatic Proliferation, Cell Survival, and Ig Production
    Byoung-gon Moon, Satoshi Takaki, Kensuke Miyake and Kiyoshi Takatsu
    J Immunol May 15, 2004, 172 (10) 6020-6029; DOI: https://doi.org/10.4049/jimmunol.172.10.6020
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    The Ability of Two Listeria monocytogenes Vaccines Targeting Human Papillomavirus-16 E7 to Induce an Antitumor Response Correlates with Myeloid Dendritic Cell Function
    Xiaohui Peng, S. Farzana Hussain and Yvonne Paterson
    J Immunol May 15, 2004, 172 (10) 6030-6038; DOI: https://doi.org/10.4049/jimmunol.172.10.6030
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    Stimulation by Soluble CD70 Promotes Strong Primary and Secondary CD8+ Cytotoxic T Cell Responses In Vivo
    Tania F. Rowley and Aymen Al-Shamkhani
    J Immunol May 15, 2004, 172 (10) 6039-6046; DOI: https://doi.org/10.4049/jimmunol.172.10.6039
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    The Role of the p38 Mitogen-Activated Protein Kinase, Extracellular Signal-Regulated Kinase, and Phosphoinositide-3-OH Kinase Signal Transduction Pathways in CD40 Ligand-Induced Dendritic Cell Activation and Expansion of Virus-Specific CD8+ T Cell Memory Responses
    Qigui Yu, Colin Kovacs, Feng Yun Yue and Mario A. Ostrowski
    J Immunol May 15, 2004, 172 (10) 6047-6056; DOI: https://doi.org/10.4049/jimmunol.172.10.6047
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    T Cells Associated with Tumor Regression Recognize Frameshifted Products of the CDKN2A Tumor Suppressor Gene Locus and a Mutated HLA Class I Gene Product
    Jianping Huang, Mona El-Gamil, Mark E. Dudley, Yong F. Li, Steven A. Rosenberg and Paul F. Robbins
    J Immunol May 15, 2004, 172 (10) 6057-6064; DOI: https://doi.org/10.4049/jimmunol.172.10.6057
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    Toll-Like Receptor Ligands Directly Promote Activated CD4+ T Cell Survival
    Andrew E. Gelman, Jidong Zhang, Yongwon Choi and Laurence A. Turka
    J Immunol May 15, 2004, 172 (10) 6065-6073; DOI: https://doi.org/10.4049/jimmunol.172.10.6065
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    The Tumoricidal Activity of Memory CD8+ T Cells Is Hampered by Persistent Systemic Antigen, but Full Functional Capacity Is Regained in an Antigen-Free Environment
    Annemieke Th. den Boer, Geertje J. D. van Mierlo, Marieke F. Fransen, Cornelis J. M. Melief, Rienk Offringa and René E. M. Toes
    J Immunol May 15, 2004, 172 (10) 6074-6079; DOI: https://doi.org/10.4049/jimmunol.172.10.6074
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    The Toll-Like Receptor-2/6 Agonist Macrophage-Activating Lipopeptide-2 Cooperates with IFN-γ to Reverse the Th2 Skew in an In Vitro Allergy Model
    Henning Weigt, Peter F. Muhlradt, Michael Larbig, Norbert Krug and Armin Braun
    J Immunol May 15, 2004, 172 (10) 6080-6086; DOI: https://doi.org/10.4049/jimmunol.172.10.6080
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    Glycoprotein 96 Can Chaperone Both MHC Class I- and Class II-Restricted Epitopes for In Vivo Presentation, but Selectively Primes CD8+ T Cell Effector Function
    Amy D. H. Doody, Joseph T. Kovalchin, Marianne A. Mihalyo, Adam T. Hagymasi, Charles G. Drake and Adam J. Adler
    J Immunol May 15, 2004, 172 (10) 6087-6092; DOI: https://doi.org/10.4049/jimmunol.172.10.6087
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    Restoration of NK T Cell Development in fyn-Mutant Mice by a TCR Reveals a Requirement for Fyn During Early NK T Cell Ontogeny
    Paul Gadue, Liqun Yin, Sumesh Jain and Paul L. Stein
    J Immunol May 15, 2004, 172 (10) 6093-6100; DOI: https://doi.org/10.4049/jimmunol.172.10.6093
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    IL-9-Induced Expansion of B-1b Cells Restores Numbers but Not Function of B-1 Lymphocytes in xid Mice
    Laurent Knoops, Jamila Louahed and Jean-Christophe Renauld
    J Immunol May 15, 2004, 172 (10) 6101-6106; DOI: https://doi.org/10.4049/jimmunol.172.10.6101
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    The Size and Phenotype of Virus-Specific T Cell Populations Is Determined by Repetitive Antigenic Stimulation and Environmental Cytokines
    Laila E. Gamadia, Ester M. M. van Leeuwen, Ester B. M. Remmerswaal, Si-La Yong, Sugianto Surachno, Pauline M. E. Wertheim-van Dillen, Ineke J. M. ten Berge and René A. W. van Lier
    J Immunol May 15, 2004, 172 (10) 6107-6114; DOI: https://doi.org/10.4049/jimmunol.172.10.6107
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    CD1d-Independent NKT Cells in β2-Microglobulin-Deficient Mice Have Hybrid Phenotype and Function of NK and T Cells
    Motoi Maeda, Ashleen Shadeo, Anna M. MacFadyen and Fumio Takei
    J Immunol May 15, 2004, 172 (10) 6115-6122; DOI: https://doi.org/10.4049/jimmunol.172.10.6115
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    Human CD4+CD25+ Regulatory T Cells Share Equally Complex and Comparable Repertoires with CD4+CD25− Counterparts
    Kimberly A. Kasow, Xiaohua Chen, James Knowles, David Wichlan, Rupert Handgretinger and Janice M. Riberdy
    J Immunol May 15, 2004, 172 (10) 6123-6128; DOI: https://doi.org/10.4049/jimmunol.172.10.6123
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    Loading of MHC Class I and II Presentation Pathways by Exogenous Antigens: A Quantitative In Vivo Comparison
    Tazio Storni and Martin F. Bachmann
    J Immunol May 15, 2004, 172 (10) 6129-6135; DOI: https://doi.org/10.4049/jimmunol.172.10.6129
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    IL-2 Secretion by CD4+ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition
    Dorothy K. Sojka, Denis Bruniquel, Ronald H. Schwartz and Nevil J. Singh
    J Immunol May 15, 2004, 172 (10) 6136-6143; DOI: https://doi.org/10.4049/jimmunol.172.10.6136

MOLECULAR AND STRUCTURAL IMMUNOLOGY

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    Transcriptional Activation of the SH2D2A Gene Is Dependent on a Cyclic Adenosine 5′-Monophosphate-Responsive Element in the Proximal SH2D2A Promoter
    Ke-Zheng Dai, Finn-Eirik Johansen, Kristin Melkevik Kolltveit, Hans-Christian Aasheim, Zlatko Dembic, Frode Vartdal and Anne Spurkland
    J Immunol May 15, 2004, 172 (10) 6144-6151; DOI: https://doi.org/10.4049/jimmunol.172.10.6144
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    Genetic Makeup of the DR Region in Rhesus Macaques: Gene Content, Transcripts, and Pseudogenes
    Nanine de Groot, Gaby G. Doxiadis, Natasja G. de Groot, Nel Otting, Corrine Heijmans, Annemiek J. M. Rouweler and Ronald E. Bontrop
    J Immunol May 15, 2004, 172 (10) 6152-6157; DOI: https://doi.org/10.4049/jimmunol.172.10.6152
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    IL-4-Induced GATA-3 Expression Is a Time-Restricted Instruction Switch for Th2 Cell Differentiation
    Noriyasu Seki, Mayumi Miyazaki, Wataru Suzuki, Katsuhiko Hayashi, Kazuhiko Arima, Elmarie Myburgh, Kenji Izuhara, Frank Brombacher and Masato Kubo
    J Immunol May 15, 2004, 172 (10) 6158-6166; DOI: https://doi.org/10.4049/jimmunol.172.10.6158
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    Fusion of Two Malaria Vaccine Candidate Antigens Enhances Product Yield, Immunogenicity, and Antibody-Mediated Inhibition of Parasite Growth In Vitro
    Weiqing Pan, Daqing Huang, Qingfeng Zhang, Li Qu, Dongmei Zhang, Xiaoli Zhang, Xiangyang Xue and Feng Qian
    J Immunol May 15, 2004, 172 (10) 6167-6174; DOI: https://doi.org/10.4049/jimmunol.172.10.6167
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    Structures of HLA-A*1101 Complexed with Immunodominant Nonamer and Decamer HIV-1 Epitopes Clearly Reveal the Presence of a Middle, Secondary Anchor Residue
    Lenong Li and Marlene Bouvier
    J Immunol May 15, 2004, 172 (10) 6175-6184; DOI: https://doi.org/10.4049/jimmunol.172.10.6175

HOST DEFENSE

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    Lipopolysaccharide-Binding Protein Critically Regulates Lipopolysaccharide-Induced IFN-β Signaling Pathway in Human Monocytes
    Atsushi Kato, Takahisa Ogasawara, Toshiki Homma, Hirohisa Saito and Kenji Matsumoto
    J Immunol May 15, 2004, 172 (10) 6185-6194; DOI: https://doi.org/10.4049/jimmunol.172.10.6185
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    Lysine-Dependent Multipoint Binding of the Borrelia burgdorferi Virulence Factor Outer Surface Protein E to the C Terminus of Factor H
    Antti Alitalo, Taru Meri, Tong Chen, Hilkka Lankinen, Zhu-Zhu Cheng, T. Sakari Jokiranta, Ilkka J. T. Seppälä, Pekka Lahdenne, P. Scott Hefty, Darrin R. Akins and Seppo Meri
    J Immunol May 15, 2004, 172 (10) 6195-6201; DOI: https://doi.org/10.4049/jimmunol.172.10.6195
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    Toll-Like Receptor 4 Dependence of Innate and Adaptive Immunity to Salmonella: Importance of the Kupffer Cell Network
    Andrés Vazquez-Torres, Bruce A. Vallance, Molly A. Bergman, B. Brett Finlay, Brad T. Cookson, Jessica Jones-Carson and Ferric C. Fang
    J Immunol May 15, 2004, 172 (10) 6202-6208; DOI: https://doi.org/10.4049/jimmunol.172.10.6202
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    Induction of HIV Immunity in the Genital Tract After Intranasal Delivery of a MVA Vector: Enhanced Immunogenicity After DNA Prime-Modified Vaccinia Virus Ankara Boost Immunization Schedule
    M. Magdalena Gherardi, Eva Pérez-Jiménez, José Luis Nájera and Mariano Esteban
    J Immunol May 15, 2004, 172 (10) 6209-6220; DOI: https://doi.org/10.4049/jimmunol.172.10.6209
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    Immunological Characteristics Associated with the Protective Efficacy of Antibodies to Ricin
    Massimo Maddaloni, Corrie Cooke, Royce Wilkinson, Audrey V. Stout, Leta Eng and Seth H. Pincus
    J Immunol May 15, 2004, 172 (10) 6221-6228; DOI: https://doi.org/10.4049/jimmunol.172.10.6221
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    Filaria-Induced Immune Evasion: Suppression by the Infective Stage of Brugia malayi at the Earliest Host-Parasite Interface
    Roshanak Tolouei Semnani, Melissa Law, Joseph Kubofcik and Thomas B. Nutman
    J Immunol May 15, 2004, 172 (10) 6229-6238; DOI: https://doi.org/10.4049/jimmunol.172.10.6229
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    Visualizing the Viral Burden: Phenotypic and Functional Alterations of T Cells and APCs during Persistent Infection
    Dirk Homann, Dorian B. McGavern and Michael B. A. Oldstone
    J Immunol May 15, 2004, 172 (10) 6239-6250; DOI: https://doi.org/10.4049/jimmunol.172.10.6239
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    Mycobacterium tuberculosis-Induced CXCR4 and Chemokine Expression Leads to Preferential X4 HIV-1 Replication in Human Macrophages
    Yoshihiko Hoshino, Doris B. Tse, Gemma Rochford, Savita Prabhakar, Satomi Hoshino, Nishay Chitkara, Kenichi Kuwabara, Elbert Ching, Bindu Raju, Jeffrey A. Gold, William Borkowsky, William N. Rom, Richard Pine and Michael Weiden
    J Immunol May 15, 2004, 172 (10) 6251-6258; DOI: https://doi.org/10.4049/jimmunol.172.10.6251
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    IgA Class Switch Occurs in the Organized Nasopharynx- and Gut-Associated Lymphoid Tissue, but Not in the Diffuse Lamina Propria of Airways and Gut
    Takashi Shikina, Takachika Hiroi, Kohichi Iwatani, Myoung Ho Jang, Satoshi Fukuyama, Manabu Tamura, Takeshi Kubo, Hiromichi Ishikawa and Hiroshi Kiyono
    J Immunol May 15, 2004, 172 (10) 6259-6264; DOI: https://doi.org/10.4049/jimmunol.172.10.6259
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    Cellular and Humoral Immunity against Vaccinia Virus Infection of Mice
    Rong Xu, Aaron J. Johnson, Denny Liggitt and Michael J. Bevan
    J Immunol May 15, 2004, 172 (10) 6265-6271; DOI: https://doi.org/10.4049/jimmunol.172.10.6265
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    Mycobacterium tuberculosis Inhibits Macrophage Responses to IFN-γ through Myeloid Differentiation Factor 88-Dependent and -Independent Mechanisms
    Sarah M. Fortune, Alejandra Solache, Alejandra Jaeger, Preston J. Hill, John T. Belisle, Barry R. Bloom, Eric J. Rubin and Joel D. Ernst
    J Immunol May 15, 2004, 172 (10) 6272-6280; DOI: https://doi.org/10.4049/jimmunol.172.10.6272
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    Dendritic Cells (DC) Activated by CpG DNA Ex Vivo Are Potent Inducers of Host Resistance to an Intracellular Pathogen That Is Independent of IL-12 Derived from the Immunizing DC
    José R. Ramírez-Pineda, Anja Fröhlich, Christof Berberich and Heidrun Moll
    J Immunol May 15, 2004, 172 (10) 6281-6289; DOI: https://doi.org/10.4049/jimmunol.172.10.6281
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    Immunogenicity of Recombinant Adenovirus Serotype 35 Vaccine in the Presence of Pre-Existing Anti-Ad5 Immunity
    Dan H. Barouch, Maria G. Pau, Jerome H. H. V. Custers, Wouter Koudstaal, Stefan Kostense, Menzo J. E. Havenga, Diana M. Truitt, Shawn M. Sumida, Michael G. Kishko, Janelle C. Arthur, Birgit Korioth-Schmitz, Michael H. Newberg, Darci A. Gorgone, Michelle A. Lifton, Dennis L. Panicali, Gary J. Nabel, Norman L. Letvin and Jaap Goudsmit
    J Immunol May 15, 2004, 172 (10) 6290-6297; DOI: https://doi.org/10.4049/jimmunol.172.10.6290
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    Mouse Strain Susceptibility to Trypanosome Infection: An Arginase-Dependent Effect
    Sébastien Duleu, Philippe Vincendeau, Pierrette Courtois, Silla Semballa, Isabelle Lagroye, Sylvie Daulouède, Jean-Luc Boucher, Keith T. Wilson, Bernard Veyret and Alain P. Gobert
    J Immunol May 15, 2004, 172 (10) 6298-6303; DOI: https://doi.org/10.4049/jimmunol.172.10.6298
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    Dendritic Cells from Mice Neonatally Vaccinated with Modified Vaccinia Virus Ankara Transfer Resistance against Herpes Simplex Virus Type I to Naive One-Week-Old Mice
    Marco Franchini, Hanspeter Hefti, Sabine Vollstedt, Bettina Glanzmann, Matthias Riesen, Mathias Ackermann, Paul Chaplin, Ken Shortman and Mark Suter
    J Immunol May 15, 2004, 172 (10) 6304-6312; DOI: https://doi.org/10.4049/jimmunol.172.10.6304
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    Viral FLIP Impairs Survival of Activated T Cells and Generation of CD8+ T Cell Memory
    Zhengqi Wu, Margaret Roberts, Melissa Porter, Fabianne Walker, E. John Wherry, John Kelly, Massimo Gadina, Elisabeth M. Silva, George A. DosReis, Marcela F. Lopes, John O’Shea, Warren J. Leonard, Rafi Ahmed and Richard M. Siegel
    J Immunol May 15, 2004, 172 (10) 6313-6323; DOI: https://doi.org/10.4049/jimmunol.172.10.6313
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    Dual Role of TLR2 and Myeloid Differentiation Factor 88 in a Mouse Model of Invasive Group B Streptococcal Disease
    Giuseppe Mancuso, Angelina Midiri, Concetta Beninati, Carmelo Biondo, Roberta Galbo, Shizuo Akira, Philipp Henneke, Douglas Golenbock and Giuseppe Teti
    J Immunol May 15, 2004, 172 (10) 6324-6329; DOI: https://doi.org/10.4049/jimmunol.172.10.6324

INFLAMMATION

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    Augmentation of Chemotherapy-Induced Cytokine Production by Expression of the Platelet-Activating Factor Receptor in a Human Epithelial Carcinoma Cell Line
    Marc Darst, Mohammed Al-Hassani, Tao Li, Qiaofang Yi, John M. Travers, Davina A. Lewis and Jeffrey B. Travers
    J Immunol May 15, 2004, 172 (10) 6330-6335; DOI: https://doi.org/10.4049/jimmunol.172.10.6330
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    Transient and Selective NF-κB p65 Serine 536 Phosphorylation Induced by T Cell Costimulation Is Mediated by IκB Kinase β and Controls the Kinetics of p65 Nuclear Import
    Ivan Mattioli, Andrea Sebald, Cyril Bucher, Roch-Philippe Charles, Hiroyasu Nakano, Takahiro Doi, Michael Kracht and M. Lienhard Schmitz
    J Immunol May 15, 2004, 172 (10) 6336-6344; DOI: https://doi.org/10.4049/jimmunol.172.10.6336
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    Intracellular Bacterial Infection-Induced IFN-γ Is Critically but Not Solely Dependent on Toll-Like Receptor 4-Myeloid Differentiation Factor 88-IFN-αβ-STAT1 Signaling
    Antonio Gigliotti Rothfuchs, Christian Trumstedt, Hans Wigzell and Martin E. Rottenberg
    J Immunol May 15, 2004, 172 (10) 6345-6353; DOI: https://doi.org/10.4049/jimmunol.172.10.6345
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    Studies of Congenic Lines in the Brown Norway Rat Model of Th2-Mediated Immunopathological Disorders Show That the Aurothiopropanol Sulfonate-Induced Immunological Disorder (Aiid3) Locus on Chromosome 9 Plays a Major Role Compared to Aiid2 on Chromosome 10
    Magali Mas, Pierre Cavaillès, Céline Colacios, Jean-François Subra, Dominique Lagrange, Maryline Calise, Marie-Odile Christen, Philippe Druet, Lucette Pelletier, Dominique Gauguier and Gilbert J. Fournié
    J Immunol May 15, 2004, 172 (10) 6354-6361; DOI: https://doi.org/10.4049/jimmunol.172.10.6354
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    The Transmembrane CXC-Chemokine Ligand 16 Is Induced by IFN-γ and TNF-α and Shed by the Activity of the Disintegrin-Like Metalloproteinase ADAM10
    Soeren Abel, Christian Hundhausen, Rolf Mentlein, Alexander Schulte, Theo A. Berkhout, Neil Broadway, Dieter Hartmann, Radek Sedlacek, Sebastian Dietrich, Barbara Muetze, Bjoern Schuster, Karl-Josef Kallen, Paul Saftig, Stefan Rose-John and Andreas Ludwig
    J Immunol May 15, 2004, 172 (10) 6362-6372; DOI: https://doi.org/10.4049/jimmunol.172.10.6362
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    6-Phosphogluconate Dehydrogenase and Glucose-6-Phosphate Dehydrogenase Form a Supramolecular Complex in Human Neutrophils That Undergoes Retrograde Trafficking during Pregnancy
    Andrei L. Kindzelskii, Tatsuya Ueki, Hitoshi Michibata, Tinnakorn Chaiworapongsa, Roberto Romero and Howard R. Petty
    J Immunol May 15, 2004, 172 (10) 6373-6381; DOI: https://doi.org/10.4049/jimmunol.172.10.6373
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    Inactivation of C5a Anaphylatoxin by a Peptide That Is Complementary to a Region of C5a
    Emiko Fujita, Imre Farkas, William Campbell, Lajos Baranyi, Hidechika Okada and Noriko Okada
    J Immunol May 15, 2004, 172 (10) 6382-6387; DOI: https://doi.org/10.4049/jimmunol.172.10.6382
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    Ectopic CD40 Ligand Expression on B Cells Triggers Intestinal Inflammation
    Takahiro Kawamura, Takanori Kanai, Taeko Dohi, Koji Uraushihara, Teruji Totsuka, Ryoichi Iiyama, Chikara Taneda, Motomi Yamazaki, Tetsuya Nakamura, Tetsuya Higuchi, Yuichi Aiba, Takeshi Tsubata and Mamoru Watanabe
    J Immunol May 15, 2004, 172 (10) 6388-6397; DOI: https://doi.org/10.4049/jimmunol.172.10.6388
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    Mast Cells, FcεRI, and IL-13 Are Required for Development of Airway Hyperresponsiveness after Aerosolized Allergen Exposure in the Absence of Adjuvant
    Christian Taube, Xudong Wei, Christina H. Swasey, Anthony Joetham, Simona Zarini, Tricia Lively, Katsuyuki Takeda, Joan Loader, Nobuaki Miyahara, Taku Kodama, Lenny D. Shultz, Debra D. Donaldson, Eckard H. Hamelmann, Azzeddine Dakhama and Erwin W. Gelfand
    J Immunol May 15, 2004, 172 (10) 6398-6406; DOI: https://doi.org/10.4049/jimmunol.172.10.6398

CLINICAL IMMUNOLOGY

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    The Functional Profile of Primary Human Antiviral CD8+ T Cell Effector Activity Is Dictated by Cognate Peptide Concentration
    Michael R. Betts, David A. Price, Jason M. Brenchley, Karin Loré, F. Javier Guenaga, Anna Smed-Sorensen, David R. Ambrozak, Stephen A. Migueles, Mark Connors, Mario Roederer, Daniel C. Douek and Richard A. Koup
    J Immunol May 15, 2004, 172 (10) 6407-6417; DOI: https://doi.org/10.4049/jimmunol.172.10.6407
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    Attenuation of Experimental Autoimmune Encephalomyelitis and Nonimmune Demyelination by IFN-β plus Vitamin B12: Treatment to Modify Notch-1/Sonic Hedgehog Balance
    Fabrizio G. Mastronardi, Weixian Min, Huimin Wang, Shawn Winer, Michael Dosch, Joan M. Boggs and Mario A. Moscarello
    J Immunol May 15, 2004, 172 (10) 6418-6426; DOI: https://doi.org/10.4049/jimmunol.172.10.6418
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    Generation and Regulation of Human Th1-Biased Immune Responses In Vivo: A Critical Role for IL-4 and IL-10
    Alla Skapenko, Gerald U. Niedobitek, Joachim R. Kalden, Peter E. Lipsky and Hendrik Schulze-Koops
    J Immunol May 15, 2004, 172 (10) 6427-6434; DOI: https://doi.org/10.4049/jimmunol.172.10.6427
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    CD4+CD25bright Regulatory T Cells Actively Regulate Inflammation in the Joints of Patients with the Remitting Form of Juvenile Idiopathic Arthritis
    Ismé M. de Kleer, Lucy R. Wedderburn, Leonie S. Taams, Alka Patel, Hemlata Varsani, Mark Klein, Wilco de Jager, Gisela Pugayung, Francesca Giannoni, Ger Rijkers, Salvatore Albani, Wietse Kuis and Berent Prakken
    J Immunol May 15, 2004, 172 (10) 6435-6443; DOI: https://doi.org/10.4049/jimmunol.172.10.6435
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    Xenobiotic-Induced Loss of Tolerance in Rabbits to the Mitochondrial Autoantigen of Primary Biliary Cirrhosis Is Reversible
    Katsushi Amano, Patrick S. C. Leung, Qingchai Xu, Jan Marik, Chao Quan, Mark J. Kurth, Michael H. Nantz, Aftab A. Ansari, Kit S. Lam, Mikio Zeniya, Ross L. Coppel and M. Eric Gershwin
    J Immunol May 15, 2004, 172 (10) 6444-6452; DOI: https://doi.org/10.4049/jimmunol.172.10.6444
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    Antiviral Cytokines Induce Hepatic Expression of the Granzyme B Inhibitors, Proteinase Inhibitor 9 and Serine Proteinase Inhibitor 6
    Mahmoud B. Barrie, Heather W. Stout, Marwan S. Abougergi, Bonnie C. Miller and Dwain L. Thiele
    J Immunol May 15, 2004, 172 (10) 6453-6459; DOI: https://doi.org/10.4049/jimmunol.172.10.6453
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    Lack of Galactose-α-1,3-Galactose Expression on Porcine Endothelial Cells Prevents Complement-Induced Lysis but Not Direct Xenogeneic NK Cytotoxicity
    Bettina C. Baumann, Pietro Forte, Robert J. Hawley, Robert Rieben, Mårten K. J. Schneider and Jörg D. Seebach
    J Immunol May 15, 2004, 172 (10) 6460-6467; DOI: https://doi.org/10.4049/jimmunol.172.10.6460
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    Type I Regulatory T Cells Specific for Desmoglein 3 Are More Frequently Detected in Healthy Individuals than in Patients with Pemphigus Vulgaris
    Christian Veldman, Annette Höhne, Detlef Dieckmann, Gerold Schuler and Michael Hertl
    J Immunol May 15, 2004, 172 (10) 6468-6475; DOI: https://doi.org/10.4049/jimmunol.172.10.6468
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    IFN-α Priming Results in a Gain of Proinflammatory Function by IL-10: Implications for Systemic Lupus Erythematosus Pathogenesis
    M. Nusrat Sharif, Ioannis Tassiulas, Yang Hu, Ingrid Mecklenbräuker, Alexander Tarakhovsky and Lionel B. Ivashkiv
    J Immunol May 15, 2004, 172 (10) 6476-6481; DOI: https://doi.org/10.4049/jimmunol.172.10.6476
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    The Novel Cyclophilin-Binding Drug Sanglifehrin A Specifically Affects Antigen Uptake Receptor Expression and Endocytic Capacity of Human Dendritic Cells
    Andrea M. Woltman, Nicole Schlagwein, Sandra W. van der Kooij and Cees van Kooten
    J Immunol May 15, 2004, 172 (10) 6482-6489; DOI: https://doi.org/10.4049/jimmunol.172.10.6482
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    Molecular Characterization of Polygalacturonases as Grass Pollen-Specific Marker Allergens: Expulsion from Pollen via Submicronic Respirable Particles
    Ines Swoboda, Monika Grote, Petra Verdino, Walter Keller, Mohan B. Singh, Nicole De Weerd, Wolfgang R. Sperr, Peter Valent, Nadja Balic, Rudolf Reichelt, Roland Suck, Helmut Fiebig, Rudolf Valenta and Susanne Spitzauer
    J Immunol May 15, 2004, 172 (10) 6490-6500; DOI: https://doi.org/10.4049/jimmunol.172.10.6490
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The Journal of Immunology: 172 (10)
The Journal of Immunology
Vol. 172, Issue 10
15 May 2004
  • Table of Contents
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  • IN THIS ISSUE
  • LETTERS TO THE EDITOR
  • BRIEF REVIEWS
  • CUTTING EDGE
  • CELLULAR IMMUNOLOGY AND IMMUNE REGULATION
  • MOLECULAR AND STRUCTURAL IMMUNOLOGY
  • HOST DEFENSE
  • INFLAMMATION
  • CLINICAL IMMUNOLOGY
  • Highlights
  • Most Cited
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Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
Osteoclasts Derive Predominantly from Bone Marrow–Resident CX3CR1+ Precursor Cells in Homeostasis, whereas Circulating CX3CR1+ Cells Contribute to Osteoclast Development during Fracture Repair
Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α
Polysaccharide Capsules Equip the Human Symbiont Bacteroides thetaiotaomicron to Modulate Immune Responses to a Dominant Antigen in the Intestine
Natural and Induced Tolerogenic Dendritic Cells
Cutting Edge: IL-6–Driven Immune Dysregulation Is Strictly Dependent on IL-6R α-Chain Expression

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